Hub : Genes

Dmpk

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr1_87862554_87863196 0.1 0.06 2.4e-13 0.11 0.1 0.1 0.1 7.5e-12 9.8e-12 3.8e-11 1.6e-11
2 PL isoform ratio XM_063261333.1 0.02 0.03 6.7e-03 0.02 0.02 0.02 0.02 1.2e-03 5.3e-03 1.3e-03 5.7e-03
3 Brain isoform ratio XM_063261313.1 0.04 0.04 2.0e-04 0.03 0.02 0.02 0.02 1.1e-03 2.5e-03 3.7e-03 5.9e-03
4 Adipose isoform ratio NM_001415848.1 0.09 0.07 1.2e-09 0.08 0.08 0.08 0.08 1.5e-09 2.7e-09 2.4e-09 2.2e-09
5 Adipose intron excision ratio chr1_87862569_87863196 0.07 0.05 2.8e-08 0.06 0.07 0.06 0.06 1.4e-07 7.0e-08 9.7e-08 1.4e-07
6 PL intron excision ratio chr1_87862554_87863196 0.03 0.03 3.5e-04 0.02 0.03 0.02 0.02 5.5e-03 3.9e-04 3.5e-03 2.3e-03
7 NAcc intron excision ratio chr1_87862569_87863196 0.04 0.04 2.4e-05 0.02 0.02 0.02 0.02 1.2e-04 2.7e-04 5.1e-04 2.9e-04
8 Adipose isoform ratio NM_001415849.1 0.03 0.03 5.4e-04 0.02 0.02 0.02 0.02 1.2e-03 1.2e-03 5.0e-03 1.9e-03
9 Adipose mRNA stability Dmpk 0.12 0.08 5.5e-14 0.12 0.12 0.12 0.12 6.0e-13 1.7e-13 7.4e-13 4.5e-13
10 Adipose isoform ratio NM_001415847.1 0.03 0.02 1.8e-03 0.02 0.02 0.02 0.02 1.3e-03 1.0e-03 2.9e-03 2.0e-03
11 Adipose gene expression Dmpk 0.17 0.1 0.0e+00 0.17 0.17 0.17 0.17 1.8e-18 7.3e-19 3.0e-18 1.1e-18
12 pVTA intron excision ratio chr1_87862554_87863196 0.06 0.05 2.8e-04 0.03 0.03 0.02 0.03 3.9e-03 1.6e-03 5.0e-03 3.2e-03
13 Brain intron excision ratio chr1_87862554_87863196 0.14 0.1 9.8e-15 0.16 0.16 0.16 0.16 2.4e-14 1.6e-14 2.3e-14 2.2e-14
14 Adipose alternative polyA XM_063261309.1 0.04 0.06 2.0e-03 0.02 0.02 0.01 0.02 8.6e-04 1.3e-03 1.6e-02 1.0e-03
15 Adipose alternative polyA XM_063261309.1 0.05 0.07 1.9e-03 0.02 0.02 0.01 0.02 8.8e-04 1.9e-03 3.9e-02 1.3e-03
16 Adipose isoform ratio NM_001372064.1 0.06 0.05 3.1e-07 0.05 0.04 0.04 0.04 7.7e-06 1.0e-05 5.6e-05 1.9e-05
17 Brain intron excision ratio chr1_87862569_87863196 0.13 0.11 1.6e-09 0.07 0.07 0.06 0.07 2.7e-07 2.2e-07 2.8e-06 6.3e-07
18 PL intron excision ratio chr1_87862569_87863196 0.09 0.11 2.2e-05 0.02 0.03 0.02 0.03 4.6e-03 1.1e-04 9.6e-04 7.1e-04
19 NAcc intron excision ratio chr1_87862554_87863196 0.05 0.04 3.3e-09 0.07 0.05 0.06 0.06 2.8e-10 5.7e-08 7.0e-10 6.7e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.00.00.10.10.10.20.20.0-0.0-0.1-0.0-0.00.0-0.0-0.00.1-0.2-0.20.2-0.1-0.10.0
Area under the delay curve1.11.62.2-1.0-1.2-1.3-1.3-1.31.31.11.31.3-1.31.31.31.4-1.5-1.51.3-1.4-1.40.0
BMI with tail0.62.24.02.01.91.71.91.5-1.5-1.5-1.5-1.51.5-1.4-1.4-1.41.31.3-1.31.21.20.0
BMI without tail0.52.65.82.42.21.92.01.7-1.6-1.8-1.6-1.71.6-1.5-1.5-1.51.31.3-1.31.21.20.0
Body weight1.35.810.33.23.12.72.82.5-2.4-2.7-2.4-2.52.4-2.3-2.3-2.32.22.2-2.12.02.00.0
Weight adjusted by age0.00.00.20.10.40.40.40.1-0.1-0.5-0.1-0.10.1-0.1-0.1-0.1-0.0-0.0-0.1-0.0-0.00.0
Bone surface0.20.40.80.90.80.80.80.7-0.7-0.6-0.7-0.70.7-0.7-0.6-0.60.60.6-0.50.50.50.0
Bone volume0.10.30.50.70.70.70.70.6-0.6-0.6-0.6-0.60.5-0.6-0.5-0.50.40.4-0.40.40.40.0
Breakpoint value in progressive ratio session1.42.53.5-1.8-1.7-1.7-1.9-1.71.71.31.71.7-1.71.71.71.6-1.6-1.61.5-1.6-1.60.0
Number of licking bursts1.33.94.41.91.92.02.02.0-2.0-2.1-2.0-2.02.0-2.0-2.0-2.12.12.1-2.12.12.10.0
Context. condit. distance diff. score0.10.10.20.1-0.00.10.10.3-0.3-0.2-0.3-0.30.3-0.3-0.3-0.40.30.3-0.30.40.40.0
Locomotion velocity, session 10.10.10.3-0.6-0.4-0.2-0.2-0.30.30.20.30.3-0.30.30.20.2-0.3-0.30.3-0.1-0.10.0
Locomotion distance, session 10.00.00.0-0.2-0.10.00.00.0-0.10.0-0.00.00.1-0.1-0.1-0.10.10.1-0.10.10.20.0
Locomotion velocity, session 21.31.62.11.51.41.31.31.3-1.3-1.3-1.3-1.31.3-1.3-1.3-1.31.21.2-1.31.21.20.0
Locomotion distance, session 20.20.30.40.60.60.60.60.5-0.6-0.5-0.6-0.50.6-0.6-0.6-0.50.50.5-0.50.50.50.0
Locomotion velocity, session 30.20.30.50.70.60.50.50.5-0.5-0.5-0.5-0.50.5-0.5-0.5-0.50.50.5-0.50.40.40.0
Locomotion distance, session 30.70.81.0-0.7-0.8-1.0-1.0-0.90.91.00.90.9-0.90.90.91.0-0.9-0.90.9-1.0-1.00.0
Stereotopy head waving bouts, day 31.01.21.41.01.01.11.11.1-1.1-1.1-1.1-1.11.1-1.1-1.1-1.21.11.1-1.11.21.20.0
Stereotopy head waving duration, day 30.91.11.60.90.91.01.01.1-1.1-1.0-1.1-1.11.1-1.1-1.1-1.21.21.2-1.21.21.30.0
Locomotion velocity, session 70.20.20.5-0.5-0.7-0.6-0.6-0.50.50.50.50.5-0.50.50.50.5-0.4-0.40.4-0.4-0.40.0
Locomotion distance, session 70.00.00.10.3-0.10.00.00.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.10.20.2-0.20.10.10.0
Stereotopy head waving bouts, day 70.91.11.40.81.01.11.11.1-1.1-1.1-1.1-1.11.1-1.1-1.1-1.11.01.0-1.01.21.20.0
Stereotopy head waving duration, day 70.81.01.10.81.01.11.11.0-1.0-1.0-1.0-1.01.0-1.0-1.0-1.00.90.9-1.01.11.10.0
Locomotion velocity, session 80.00.00.1-0.1-0.3-0.2-0.2-0.10.10.20.10.1-0.10.10.10.0-0.0-0.00.00.00.00.0
Locomotion distance, session 80.00.00.00.0-0.1-0.1-0.10.0-0.00.1-0.0-0.00.0-0.1-0.0-0.0-0.0-0.00.00.00.00.0
Degree of sensitization distance0.50.50.70.70.50.70.70.7-0.7-0.7-0.7-0.70.8-0.7-0.8-0.80.80.8-0.80.80.80.0
Degree of sensitization stereotypy1.01.11.50.91.11.21.21.1-1.1-1.2-1.1-1.11.1-1.1-1.1-1.11.01.0-1.01.11.10.0
Conditioned locomotion0.00.00.1-0.3-0.2-0.2-0.2-0.20.20.20.20.2-0.20.20.20.2-0.2-0.20.2-0.2-0.20.0
Cocaine response after cond. corrected0.40.50.70.60.60.60.60.8-0.8-0.7-0.8-0.80.8-0.8-0.8-0.80.80.8-0.80.80.80.0
Cocaine response after cond. not corrected1.01.41.61.11.11.11.11.2-1.3-1.2-1.2-1.21.3-1.3-1.3-1.31.31.3-1.31.31.30.0
Cocaine response before conditioning1.61.92.41.51.41.51.51.4-1.4-1.5-1.4-1.41.4-1.4-1.4-1.41.31.3-1.31.31.30.0
Saline control response1.92.63.01.61.61.71.71.7-1.7-1.5-1.7-1.71.7-1.7-1.7-1.71.71.7-1.71.71.70.0
Bone: connectivity density0.00.10.20.10.00.10.0-0.20.20.10.20.2-0.20.20.20.3-0.4-0.40.4-0.4-0.40.0
Bone: cortical apparent density0.10.10.3-0.2-0.2-0.1-0.0-0.30.30.10.30.2-0.30.30.30.3-0.5-0.50.5-0.3-0.30.0
Bone: cortical area1.42.32.71.61.61.41.41.6-1.6-1.4-1.6-1.61.6-1.6-1.6-1.61.61.6-1.61.51.50.0
Bone: cortical porosity0.10.10.4-0.3-0.3-0.6-0.7-0.40.40.50.40.4-0.40.40.40.3-0.3-0.30.2-0.3-0.30.0
Bone: cortical porosity0.00.00.10.10.1-0.2-0.20.0-0.00.1-0.0-0.10.0-0.0-0.0-0.10.10.1-0.10.10.00.0
Bone: cortical thickness0.50.91.01.00.90.90.91.0-1.0-0.9-1.0-1.01.0-1.0-1.0-1.01.01.0-1.01.01.00.0
Bone: cortical thickness1.31.61.81.31.31.31.21.3-1.3-1.1-1.3-1.31.3-1.3-1.3-1.31.21.2-1.31.31.30.0
Bone: cortical tissue density0.10.20.4-0.3-0.3-0.2-0.1-0.40.40.20.40.4-0.40.40.40.4-0.6-0.60.6-0.5-0.50.0
Condit. Reinf. active minus inactive responses0.40.50.90.91.00.80.90.7-0.7-0.8-0.7-0.70.7-0.7-0.7-0.70.50.5-0.60.60.50.0
Condit. Reinf. active-inactive response ratio0.30.30.70.80.90.70.80.6-0.6-0.7-0.6-0.60.6-0.6-0.6-0.50.30.3-0.40.40.40.0
Condit. Reinf. active responses0.20.30.60.80.70.60.70.6-0.5-0.6-0.5-0.60.5-0.5-0.5-0.50.30.3-0.40.40.40.0
Condit. Reinf. inactive responses0.10.10.2-0.3-0.4-0.4-0.4-0.30.30.40.30.3-0.30.30.30.3-0.3-0.30.2-0.3-0.30.0
Incentive salience index mean0.30.40.90.91.00.80.80.6-0.6-0.8-0.6-0.70.6-0.6-0.6-0.50.40.4-0.40.40.40.0
Condit. Reinf. lever presses0.10.10.40.60.60.40.50.3-0.2-0.4-0.2-0.30.2-0.2-0.2-0.10.00.0-0.00.0-0.00.0
Condit. Reinf. active minus inactive responses0.00.10.10.10.10.10.20.3-0.3-0.3-0.2-0.20.3-0.2-0.3-0.30.20.2-0.30.30.30.0
Condit. Reinf. active-inactive response ratio0.20.30.50.30.20.40.40.6-0.6-0.5-0.6-0.50.6-0.6-0.6-0.60.60.6-0.70.70.70.0
Condit. Reinf. active responses0.10.10.2-0.4-0.3-0.4-0.3-0.30.30.20.30.3-0.30.30.30.3-0.4-0.40.3-0.3-0.30.0
Condit. Reinf. inactive responses0.50.80.9-0.8-0.7-0.9-0.8-0.90.90.90.90.9-0.90.90.90.9-1.0-1.00.9-0.9-0.90.0
Condit. Reinf. lever presses0.10.10.20.50.50.20.30.4-0.4-0.3-0.4-0.40.4-0.4-0.4-0.40.40.4-0.40.40.40.0
Condit. Reinf. lever reinforcers received0.10.10.2-0.4-0.4-0.5-0.4-0.40.40.30.40.4-0.30.40.30.3-0.4-0.40.3-0.3-0.30.0
Conditioned reinforcement - actives0.62.33.71.91.91.91.81.6-1.6-1.3-1.6-1.61.5-1.5-1.5-1.51.41.4-1.41.41.30.0
Conditioned reinforcement - inactives0.41.02.71.61.61.21.31.0-0.9-1.1-0.9-1.00.9-0.9-0.9-0.80.80.8-0.80.60.60.0
Conditioned locomotion1.82.74.11.41.52.01.91.7-1.7-1.6-1.7-1.61.7-1.7-1.7-1.71.71.7-1.71.81.80.0
Patch foraging indifference point 0 sec0.20.51.00.40.50.30.30.8-0.8-0.6-0.8-0.80.8-0.8-0.8-0.90.90.9-0.81.01.00.0
Patch foraging indifference point AUC2.15.07.22.62.52.72.72.2-2.2-2.5-2.2-2.22.2-2.2-2.2-2.22.22.2-2.12.02.00.0
Delay disc. indifference point, 0s delay0.91.11.6-0.7-0.7-0.9-0.9-1.11.10.81.11.0-1.11.11.11.1-1.2-1.21.2-1.2-1.30.0
Delay disc. indifference point, 16s delay0.81.11.5-0.6-0.9-1.0-1.0-1.01.01.11.01.0-1.01.01.11.1-1.2-1.21.2-1.2-1.20.0
Delay disc. indifference point, 2s delay2.73.14.1-1.3-1.4-1.5-1.5-1.81.81.61.81.8-1.91.91.91.9-2.0-2.01.8-2.0-2.00.0
Delay disc. indifference point, 24s delay0.00.00.1-0.0-0.3-0.2-0.20.1-0.10.1-0.1-0.10.2-0.2-0.2-0.20.00.0-0.20.20.20.0
Delay disc. indifference point, 4s delay0.00.00.10.10.20.10.10.0-0.0-0.3-0.0-0.0-0.00.00.00.0-0.1-0.1-0.1-0.0-0.00.0
Delay disc. indifference point, 8s delay1.01.71.9-1.3-1.4-1.3-1.3-1.41.41.21.41.4-1.41.41.41.4-1.3-1.31.3-1.4-1.40.0
Indifference point function ln k0.72.14.7-2.0-1.8-2.1-2.2-1.41.41.81.31.4-1.31.31.31.2-1.3-1.31.3-1.0-1.00.0
Indifference point function log k0.72.14.7-2.0-1.8-2.1-2.2-1.41.41.81.31.4-1.31.31.31.2-1.3-1.31.3-1.0-1.00.0
Patch foraging total patch changes 0 sec0.30.81.50.50.70.50.50.9-1.0-0.8-1.0-0.91.0-1.0-1.0-1.11.11.1-1.01.21.20.0
Patch foraging total patch changes 12 sec1.72.23.51.91.81.71.71.5-1.5-1.6-1.5-1.51.5-1.4-1.4-1.41.41.4-1.41.31.30.0
Patch foraging total patch changes 18 sec1.22.93.61.41.61.91.81.7-1.7-1.9-1.7-1.71.7-1.7-1.7-1.71.81.8-1.71.81.80.0
Patch foraging total patch changes 24 sec0.20.82.11.11.31.41.40.8-0.8-1.1-0.8-0.80.8-0.8-0.8-0.80.80.8-0.60.60.60.0
Patch foraging total patch changes 6 sec2.03.43.91.81.81.61.71.9-1.9-1.7-1.9-1.91.9-1.9-1.9-1.92.02.0-1.92.02.00.0
Patch foraging time to switch 0 sec1.24.55.2-2.1-2.1-1.9-1.9-2.22.22.02.22.2-2.22.22.22.2-2.3-2.32.2-2.3-2.30.0
Patch foraging water rate 0 sec1.45.46.22.32.52.12.12.4-2.4-2.2-2.4-2.42.4-2.4-2.4-2.42.42.4-2.42.52.50.0
Patch foraging water rate 12 sec0.00.20.30.30.50.30.20.4-0.5-0.3-0.5-0.40.5-0.5-0.5-0.40.40.4-0.40.50.50.0
Patch foraging water rate 18 sec0.10.10.40.40.60.30.20.4-0.4-0.1-0.4-0.40.4-0.4-0.4-0.40.40.4-0.40.40.40.0
Patch foraging water rate 24 sec0.40.60.90.40.70.50.50.8-0.8-0.7-0.8-0.70.8-0.8-0.8-0.80.80.8-0.90.90.90.0
Patch foraging water rate 6 sec0.60.91.51.01.21.01.01.0-1.0-0.9-1.0-0.91.0-1.0-1.0-0.90.90.9-0.90.90.90.0
Seeking ratio, delayed vs. immediate footshock1.62.22.8-1.7-1.5-1.5-1.6-1.51.51.41.51.5-1.51.51.51.5-1.5-1.51.6-1.5-1.50.0
Distance traveled before self-admin0.00.10.10.10.00.10.30.2-0.3-0.0-0.3-0.20.3-0.3-0.3-0.30.30.3-0.20.30.30.0
Distance traveled after self-admin0.10.20.6-0.5-0.5-0.6-0.5-0.50.50.80.50.5-0.50.50.50.5-0.4-0.40.4-0.4-0.40.0
Extensor digitorum longus weight1.87.49.43.02.93.12.82.8-2.8-2.9-2.8-2.82.7-2.8-2.7-2.72.82.8-2.72.62.60.0
Bone: elastic displacement0.70.91.2-0.8-0.8-0.8-0.9-1.01.00.61.00.9-1.01.01.01.0-1.1-1.11.0-1.0-1.00.0
Bone: elastic work0.00.10.20.50.40.30.20.2-0.2-0.3-0.2-0.30.2-0.2-0.2-0.20.10.1-0.10.10.10.0
Bone: endosteal estimation0.00.00.10.20.1-0.2-0.2-0.20.20.20.20.2-0.20.20.20.2-0.2-0.20.2-0.3-0.40.0
Bone: endosteal perimeter0.00.00.00.10.1-0.2-0.10.0-0.00.1-0.0-0.00.00.00.00.00.00.0-0.0-0.0-0.10.0
Epididymis fat weight0.10.60.9-0.5-0.4-0.6-0.6-0.80.80.70.80.7-0.80.80.80.8-0.9-0.90.9-0.9-0.90.0
Delta time in closed arm before/after self-admin0.30.30.9-0.8-0.9-0.9-0.8-0.50.40.70.40.5-0.40.40.40.4-0.4-0.40.4-0.2-0.20.0
Delta time in open arm before/after self-admin0.10.10.40.50.60.60.60.00.0-0.20.0-0.0-0.00.10.10.1-0.1-0.10.1-0.3-0.30.0
Diff in mean of infusions in LGA sessions0.81.51.9-1.4-1.3-1.1-1.0-1.31.30.91.31.3-1.31.31.31.3-1.2-1.21.2-1.2-1.20.0
Delay discount exponential model param0.91.21.60.81.01.11.11.1-1.1-0.9-1.1-1.11.1-1.1-1.1-1.11.31.3-1.11.21.20.0
Extinction: sum of active levers before priming0.00.00.1-0.2-0.2-0.3-0.3-0.20.20.00.20.2-0.20.20.20.2-0.1-0.1-0.0-0.2-0.20.0
Active lever presses in extinction session 60.10.10.50.60.70.30.20.4-0.3-0.5-0.3-0.40.3-0.3-0.3-0.30.30.3-0.40.20.20.0
Bone: final force0.40.61.01.00.90.80.80.8-0.8-0.8-0.8-0.80.8-0.8-0.8-0.80.80.8-0.80.70.70.0
Bone: final moment0.60.91.41.21.20.90.91.0-1.0-1.0-1.0-1.01.0-1.0-1.0-1.01.01.0-1.00.90.90.0
Food consumed during 24 hour testing period3.36.77.6-2.7-2.5-2.6-2.6-2.72.72.62.72.7-2.72.72.72.7-2.7-2.72.8-2.7-2.70.0
Glucose0.30.41.0-1.0-0.9-0.8-0.7-0.70.70.70.70.7-0.70.70.60.6-0.6-0.60.5-0.5-0.50.0
Heart weight1.93.03.81.61.51.71.71.8-1.8-1.5-1.8-1.81.8-1.8-1.8-1.81.91.9-1.91.91.90.0
Delay discount hyperbolic model param0.81.01.40.80.91.01.01.0-1.0-0.8-1.0-1.01.1-1.1-1.1-1.11.21.2-1.01.11.10.0
Intermittent access intake day 1-15 change0.00.10.20.50.40.40.40.4-0.4-0.4-0.4-0.40.4-0.4-0.4-0.40.40.4-0.40.40.40.0
Intermittent access intake escalation0.00.20.40.70.60.50.60.5-0.5-0.5-0.5-0.50.5-0.5-0.5-0.50.50.5-0.50.40.40.0
Intermittent access intake escalation 20.00.00.2-0.3-0.4-0.4-0.3-0.00.00.00.00.00.0-0.0-0.0-0.00.10.1-0.10.10.20.0
Intermitt. access day 1 inactive lever presses0.00.00.20.50.40.30.20.2-0.1-0.4-0.1-0.20.1-0.1-0.1-0.10.10.1-0.1-0.0-0.00.0
Intermitt. access day 15 inactive lever presses0.00.10.70.20.40.60.50.1-0.1-0.8-0.1-0.10.1-0.1-0.1-0.00.00.0-0.0-0.0-0.00.0
Intermitt. access escalation Index0.10.30.4-0.6-0.6-0.5-0.5-0.50.50.50.50.5-0.50.50.50.5-0.6-0.60.6-0.5-0.50.0
Intermittent access day 1 total infusions0.92.84.82.12.22.02.11.7-1.7-1.6-1.7-1.71.7-1.6-1.6-1.61.51.5-1.51.41.40.0
Intermittent access day 15 total infusions0.61.42.81.41.41.71.71.2-1.2-1.4-1.1-1.21.1-1.1-1.1-1.11.11.1-1.11.01.00.0
Intermittent access terminal intake (last 3 days)0.91.62.51.41.41.61.51.3-1.3-1.4-1.3-1.21.3-1.2-1.3-1.21.21.2-1.21.21.20.0
Intermittent access total infusions2.73.24.81.92.02.22.11.8-1.8-2.0-1.8-1.81.8-1.8-1.8-1.71.71.7-1.71.61.60.0
Intermittent access day 1 locomotion0.30.51.31.01.01.11.20.7-0.7-0.9-0.7-0.70.7-0.7-0.7-0.60.60.6-0.60.50.50.0
Intermittent access day 15 total locomotion0.10.30.80.60.70.70.90.5-0.5-0.6-0.5-0.50.5-0.5-0.5-0.50.50.5-0.50.40.40.0
Intermittent access total locomotion1.82.13.31.61.61.71.81.5-1.5-1.6-1.5-1.41.4-1.4-1.4-1.41.41.4-1.41.31.30.0
Intermittent access standard deviation0.00.20.3-0.5-0.6-0.4-0.4-0.50.50.20.50.5-0.50.50.50.4-0.4-0.40.4-0.4-0.40.0
Left kidney weight3.124.631.25.65.55.15.15.2-5.2-5.1-5.1-5.15.1-5.1-5.1-5.04.94.9-4.94.84.80.0
Right kidney weight3.222.126.65.25.04.84.84.9-4.9-4.9-4.9-4.84.9-4.8-4.9-4.84.74.7-4.74.74.70.0
Cocaine induced anxiety0.10.10.3-0.0-0.00.30.2-0.40.4-0.00.40.3-0.40.40.40.4-0.5-0.50.5-0.5-0.60.0
Post-drug Anxiety0.00.00.0-0.1-0.10.10.0-0.10.20.10.10.1-0.20.20.20.1-0.1-0.10.1-0.1-0.10.0
Baseline Anxiety0.10.21.0-1.0-1.0-0.8-0.8-0.20.20.60.20.2-0.10.10.10.00.10.1-0.10.20.30.0
Tail length0.31.83.82.01.81.41.41.4-1.3-1.6-1.3-1.41.3-1.3-1.3-1.21.11.1-1.21.11.10.0
Length with tail0.41.83.51.91.81.51.51.4-1.3-1.6-1.3-1.41.3-1.3-1.3-1.21.11.1-1.11.11.10.0
Length without tail0.21.11.91.21.41.31.31.1-1.1-1.3-1.1-1.01.1-1.0-1.1-1.00.90.9-0.90.90.90.0
Times rat made contact with spout0.10.10.2-0.4-0.3-0.4-0.4-0.20.20.30.20.2-0.20.20.20.2-0.2-0.20.2-0.1-0.10.0
Lifetime Intake2.73.35.22.12.12.32.21.8-1.8-2.0-1.8-1.81.8-1.8-1.8-1.81.71.7-1.71.61.60.0
Liver weight, left2.13.64.62.12.12.02.02.0-2.0-1.9-2.0-2.02.0-2.0-1.9-2.01.81.8-1.91.91.90.0
Liver weight, right1.42.54.32.12.01.81.91.7-1.6-1.7-1.6-1.71.6-1.6-1.6-1.51.31.3-1.31.41.30.0
Locomotor activity2.03.24.01.61.71.61.61.8-1.8-1.7-1.8-1.81.9-1.8-1.9-1.92.02.0-2.01.92.00.0
Locomotor testing distance0.82.12.41.41.51.51.51.5-1.5-1.3-1.5-1.41.5-1.5-1.5-1.51.61.6-1.61.41.40.0
Locomotor testing rearing2.38.69.93.13.13.13.13.0-3.0-3.0-3.0-3.03.0-3.0-3.0-3.03.03.0-3.02.92.90.0
Locomotion in novel chamber0.40.51.5-1.0-1.0-1.2-1.2-0.60.61.00.60.6-0.50.50.50.5-0.4-0.40.3-0.3-0.30.0
Locomotion in novel chamber post-restriction0.51.52.6-1.2-1.3-1.6-1.5-1.21.21.31.21.2-1.21.21.21.2-1.1-1.11.2-1.2-1.10.0
Fecal boli incidents, locomotor time 10.00.10.20.50.40.10.10.3-0.3-0.3-0.3-0.30.2-0.2-0.2-0.20.30.3-0.20.20.20.0
Change in fecal boli incidents, locomotor task0.60.60.9-0.6-0.9-0.7-0.8-0.80.80.70.80.8-0.80.80.80.9-0.9-0.90.9-0.9-0.90.0
Time >=10cm from walls, locomotor time 10.00.00.0-0.0-0.1-0.00.0-0.00.00.10.00.0-0.00.00.00.1-0.1-0.10.1-0.1-0.10.0
Bouts of movement, locomotor time 12.02.63.1-1.7-1.8-1.7-1.6-1.71.71.51.71.7-1.71.71.71.7-1.7-1.71.7-1.6-1.60.0
Total resting periods, locomotor time 12.83.23.7-1.8-1.9-1.8-1.7-1.91.91.61.91.9-1.91.91.91.9-1.9-1.91.9-1.9-1.90.0
Rest time, locomotor task time 10.10.20.4-0.4-0.6-0.5-0.4-0.50.50.30.50.5-0.50.50.50.5-0.4-0.40.5-0.5-0.50.0
Distance moved, locomotor task time 10.20.50.80.70.90.80.80.8-0.8-0.7-0.8-0.80.8-0.7-0.8-0.80.70.7-0.80.80.80.0
Vertical activity count, locomotor time 10.00.00.20.40.50.30.30.1-0.1-0.0-0.1-0.10.0-0.0-0.0-0.00.00.00.0-0.1-0.10.0
Time >=10cm from walls, locomotor time 20.00.10.2-0.2-0.1-0.3-0.2-0.20.20.40.20.2-0.20.20.30.2-0.2-0.20.2-0.3-0.30.0
Bouts of movement, locomotor time 22.27.49.9-3.1-3.0-2.8-2.7-2.82.82.72.82.8-2.82.82.82.7-2.8-2.82.7-2.6-2.60.0
Total resting periods, locomotor time 21.76.79.6-3.1-2.9-2.7-2.6-2.72.72.52.72.7-2.62.62.62.6-2.7-2.72.5-2.5-2.40.0
Rest time, locomotor task time 20.00.10.3-0.5-0.5-0.3-0.2-0.30.30.00.30.3-0.30.30.20.3-0.2-0.20.3-0.2-0.20.0
Distance moved, locomotor task time 20.71.01.51.11.20.91.01.0-1.0-0.9-1.0-1.01.0-1.0-1.0-1.00.90.9-1.01.00.90.0
Vertical activity count, locomotor time 20.00.00.20.40.3-0.00.0-0.10.10.20.10.1-0.20.20.20.2-0.2-0.20.2-0.3-0.40.0
Light reinforcement 10.00.10.20.50.40.50.50.4-0.4-0.2-0.4-0.40.4-0.4-0.4-0.30.40.4-0.30.30.30.0
Light reinforcement 20.10.31.11.11.10.80.80.5-0.4-0.7-0.4-0.50.4-0.4-0.4-0.30.40.4-0.30.10.10.0
Bone: marrow area0.00.00.10.20.1-0.2-0.2-0.10.10.20.10.1-0.10.10.10.2-0.1-0.10.1-0.3-0.30.0
Bone: maximum diameter2.04.14.82.22.11.92.02.1-2.1-2.0-2.1-2.12.1-2.1-2.1-2.12.12.1-2.12.02.00.0
Bone: maximum force0.10.30.50.70.60.50.40.6-0.6-0.5-0.6-0.60.6-0.6-0.6-0.50.50.5-0.50.50.50.0
Bone: maximum moment0.20.40.80.90.80.50.50.7-0.7-0.6-0.7-0.70.7-0.7-0.7-0.60.70.7-0.70.60.60.0
Mean time between licks in bursts0.00.10.1-0.1-0.1-0.2-0.2-0.20.20.10.20.2-0.20.20.20.3-0.3-0.30.3-0.3-0.30.0
Mean num. licks in bursts1.64.45.2-2.2-2.2-2.3-2.3-2.12.12.32.12.2-2.12.12.12.2-2.2-2.22.2-2.1-2.10.0
Cd content in liver0.10.10.5-0.7-0.5-0.2-0.2-0.40.30.20.30.4-0.30.30.30.3-0.3-0.30.3-0.2-0.20.0
Co content in liver1.11.31.5-1.2-1.1-1.0-1.0-1.21.21.01.21.2-1.21.21.21.2-1.2-1.21.2-1.2-1.20.0
Cu content in liver0.40.50.80.70.80.90.80.7-0.7-0.8-0.7-0.70.7-0.7-0.7-0.70.70.7-0.60.60.60.0
Fe content in liver4.75.86.92.02.22.52.52.5-2.5-2.5-2.5-2.42.5-2.5-2.5-2.52.52.5-2.52.62.60.0
K content in liver0.30.20.70.80.80.50.40.5-0.5-0.4-0.5-0.50.5-0.5-0.4-0.50.50.5-0.50.40.30.0
Mg content in liver0.60.61.11.11.00.80.80.9-0.8-0.8-0.8-0.90.8-0.8-0.8-0.80.80.8-0.80.70.70.0
Mn content in liver1.01.12.11.31.51.11.11.1-1.1-1.1-1.1-1.11.1-1.1-1.1-1.01.01.0-1.01.00.90.0
Na content in liver0.20.20.40.20.30.40.20.4-0.4-0.2-0.4-0.40.4-0.5-0.4-0.50.60.6-0.60.60.60.0
Rb content in liver0.00.10.10.10.30.10.10.3-0.3-0.1-0.3-0.30.3-0.3-0.3-0.20.30.3-0.20.30.30.0
Se content in liver4.04.76.32.22.52.22.22.2-2.2-2.2-2.2-2.22.2-2.2-2.2-2.22.22.2-2.22.22.20.0
Sr content in liver0.00.00.00.20.20.20.20.2-0.2-0.2-0.2-0.20.2-0.2-0.2-0.20.20.2-0.20.20.20.0
Zn content in liver0.81.01.61.31.21.11.01.0-1.0-1.0-1.0-1.01.0-1.0-1.0-1.01.01.0-1.00.90.90.0
Bone: minimum diameter0.20.30.50.70.60.50.50.6-0.6-0.4-0.6-0.60.6-0.6-0.6-0.60.60.6-0.60.50.50.0
Time in familiar zone, hab. session 10.10.10.20.20.20.20.20.4-0.4-0.2-0.4-0.40.4-0.4-0.4-0.40.50.5-0.50.50.50.0
Time in novel zone, hab. session 10.60.71.00.91.01.01.00.8-0.8-1.0-0.8-0.80.8-0.8-0.8-0.80.70.7-0.80.80.80.0
Total zone transitions, hab. session 10.10.10.20.20.20.40.40.4-0.4-0.3-0.4-0.40.4-0.4-0.4-0.40.40.4-0.40.40.50.0
Total locomotion distance, hab. session 10.30.50.6-0.7-0.6-0.7-0.7-0.70.70.80.70.7-0.70.70.70.7-0.8-0.80.7-0.7-0.70.0
Locomotion velocity, hab. session 11.11.61.9-1.2-1.2-1.2-1.2-1.31.31.31.31.3-1.31.31.31.3-1.4-1.41.3-1.3-1.30.0
Time in familiar zone, hab. session 20.30.30.60.60.60.70.70.6-0.6-0.8-0.6-0.60.6-0.6-0.6-0.60.50.5-0.50.60.60.0
Time in novel zone, hab. session 20.10.10.3-0.6-0.5-0.6-0.6-0.30.30.60.30.3-0.30.30.30.3-0.2-0.20.2-0.2-0.20.0
Total zone transitions, hab. session 20.50.60.80.60.70.80.80.8-0.8-0.7-0.8-0.80.8-0.8-0.8-0.80.80.8-0.80.90.90.0
Total locomotion distance, hab. session 20.50.60.7-0.8-0.7-0.7-0.7-0.80.80.80.80.8-0.80.80.80.8-0.8-0.80.8-0.8-0.80.0
Locomotion velocity, hab. session 20.30.40.5-0.6-0.5-0.6-0.6-0.60.60.70.60.6-0.60.60.70.6-0.7-0.70.7-0.7-0.70.0
Novel to familiar place preference ratio0.30.40.50.70.60.60.60.7-0.7-0.5-0.7-0.60.7-0.7-0.7-0.60.70.7-0.70.60.70.0
Novelty place preference0.30.30.50.60.50.50.50.6-0.6-0.5-0.6-0.60.7-0.7-0.7-0.60.70.7-0.70.60.60.0
Time in novel zone, NPP test0.40.50.60.60.60.50.50.7-0.7-0.5-0.7-0.70.8-0.8-0.8-0.70.80.8-0.80.70.80.0
Total zone transitions, NPP test0.10.10.20.30.20.20.20.4-0.4-0.1-0.4-0.30.4-0.4-0.4-0.40.40.4-0.40.40.40.0
Total locomotion distance, NPP test0.10.10.20.10.10.10.10.3-0.3-0.1-0.3-0.30.3-0.3-0.3-0.30.40.4-0.40.40.40.0
Locomotion velocity, NPP test0.00.10.10.10.10.10.10.2-0.2-0.0-0.2-0.20.3-0.3-0.3-0.30.30.3-0.30.30.30.0
Intraocular pressure0.00.10.5-0.7-0.5-0.5-0.4-0.20.20.20.20.2-0.10.20.10.1-0.1-0.10.10.10.10.0
Delta distance traveled before/after self-admin1.31.42.4-0.7-0.6-1.0-1.0-1.31.31.11.31.2-1.31.31.31.4-1.3-1.31.2-1.5-1.50.0
Delta ambulatory time before/after self-admin0.20.30.6-0.2-0.2-0.4-0.5-0.60.60.70.60.6-0.60.60.60.7-0.6-0.60.6-0.7-0.80.0
Parametrial fat weight0.10.20.30.60.50.40.40.4-0.4-0.3-0.4-0.40.4-0.4-0.4-0.40.40.4-0.40.30.30.0
Pavlov. Cond. lever latency0.50.71.0-0.9-1.0-1.0-1.0-0.80.80.90.80.9-0.80.80.80.8-0.7-0.70.7-0.8-0.80.0
Pavlov. Cond. magazine entry latency0.10.10.40.40.60.40.40.4-0.3-0.4-0.3-0.40.3-0.3-0.3-0.30.10.1-0.20.20.20.0
Pavlov. Cond. change in total contacts0.50.60.8-0.7-0.6-0.6-0.6-0.80.80.60.80.8-0.80.80.80.8-0.9-0.90.9-0.8-0.80.0
Pavlov. Cond. index score0.30.30.60.60.80.70.80.6-0.6-0.7-0.6-0.60.6-0.6-0.6-0.60.50.5-0.50.50.50.0
Pavlov. Cond. latency score0.10.10.30.30.50.50.50.3-0.3-0.4-0.3-0.30.3-0.3-0.3-0.30.20.2-0.20.20.20.0
Pavlov. Cond. lever contacts0.40.40.70.70.80.80.80.7-0.7-0.8-0.7-0.70.6-0.6-0.6-0.60.50.5-0.50.60.60.0
Pavlov. Cond. magazine entry number0.00.00.3-0.2-0.5-0.3-0.3-0.20.20.30.20.2-0.20.10.20.20.00.00.0-0.1-0.10.0
Pavlov. Cond. intertrial magazine entries0.10.10.10.20.10.30.30.2-0.2-0.3-0.2-0.20.2-0.2-0.2-0.20.40.4-0.40.30.30.0
Pavlov. Cond. lever-magazine prob. diff.0.30.40.60.60.80.70.80.6-0.6-0.7-0.6-0.60.6-0.6-0.6-0.60.50.5-0.50.60.60.0
Pavlov. Cond. response bias0.81.11.71.21.31.11.21.1-1.1-1.1-1.1-1.11.1-1.0-1.0-1.00.80.8-0.90.90.90.0
Pavlov. Cond. lever latency0.00.00.0-0.2-0.2-0.1-0.1-0.10.10.10.10.1-0.10.10.10.1-0.2-0.20.2-0.1-0.10.0
Pavlov. Cond. magazine entry latency0.00.00.00.1-0.00.10.20.1-0.1-0.2-0.1-0.00.1-0.0-0.1-0.00.00.0-0.0-0.0-0.00.0
Pavlov. Cond. change in total contacts0.10.30.5-0.7-0.6-0.7-0.7-0.60.60.70.60.6-0.60.60.50.5-0.5-0.50.5-0.5-0.50.0
Pavlov. Cond. index score0.00.00.1-0.1-0.1-0.2-0.2-0.20.20.20.20.2-0.20.20.20.2-0.2-0.20.2-0.2-0.20.0
Pavlov. Cond. latency score0.10.10.1-0.2-0.3-0.3-0.3-0.30.30.30.30.3-0.30.30.30.3-0.3-0.30.3-0.3-0.30.0
Pavlov. Cond. lever contacts0.10.10.20.40.40.20.30.3-0.3-0.3-0.3-0.30.3-0.3-0.3-0.30.30.3-0.30.30.20.0
Pavlov. Cond. magazine entry number0.30.40.50.60.60.60.50.6-0.7-0.6-0.7-0.70.7-0.7-0.7-0.70.60.6-0.60.70.70.0
Pavlov. Cond. intertrial magazine entries0.00.00.0-0.10.00.0-0.00.1-0.10.0-0.1-0.10.1-0.1-0.1-0.10.10.1-0.10.20.20.0
Pavlov. Cond. lever-magazine prob. diff.0.00.00.00.00.0-0.00.00.0-0.0-0.00.00.00.00.0-0.00.00.00.0-0.0-0.0-0.00.0
Pavlov. Cond. response bias0.00.00.0-0.00.0-0.1-0.0-0.00.10.10.10.1-0.10.10.10.1-0.0-0.00.0-0.1-0.10.0
Time in closed arm before self-admin0.61.01.80.81.01.31.31.0-1.0-1.2-1.0-0.91.0-1.0-1.0-1.01.01.0-1.00.91.00.0
Time in closed arm after self-admin0.91.12.1-1.3-1.5-1.1-1.0-1.01.01.21.01.1-1.01.01.01.0-1.0-1.01.0-0.8-0.80.0
Time in open arm before self-admin0.70.91.9-0.8-1.0-1.4-1.4-0.90.91.10.90.9-0.90.90.90.9-0.9-0.90.9-0.9-0.90.0
Time in open arm after self-admin0.00.10.20.20.2-0.0-0.2-0.20.2-0.00.20.2-0.20.20.30.3-0.2-0.20.1-0.4-0.40.0
Bone: periosteal estimation0.20.51.11.00.90.60.60.8-0.8-0.6-0.8-0.80.8-0.8-0.7-0.70.80.8-0.80.70.60.0
Bone: periosteal perimeter0.20.50.80.90.90.60.60.7-0.7-0.6-0.7-0.70.7-0.7-0.7-0.70.70.7-0.70.60.60.0
Bone: post-yield work0.61.01.4-0.8-0.9-1.0-0.9-1.01.01.01.01.0-1.01.01.01.1-1.1-1.11.1-1.2-1.20.0
Progressive ratio test 1 active lever presses2.03.55.42.32.32.12.11.9-1.9-2.0-1.9-1.91.9-1.9-1.9-1.81.81.8-1.81.71.60.0
Progressive ratio test 1 breakpoint1.93.25.62.42.22.02.11.9-1.8-1.9-1.8-1.91.8-1.8-1.8-1.71.71.7-1.71.61.50.0
Progressive ratio test 1 inactive lever presses0.82.13.31.81.71.61.81.5-1.5-1.6-1.5-1.51.4-1.4-1.4-1.41.41.4-1.41.31.20.0
Progressive ratio test 2 active lever presses2.23.14.92.12.22.22.11.8-1.8-1.8-1.8-1.81.7-1.7-1.7-1.71.71.7-1.71.61.50.0
Progressive ratio test 2 breakpoint2.73.55.42.22.32.32.21.9-1.9-2.0-1.9-1.91.8-1.8-1.8-1.81.71.7-1.71.61.60.0
Progressive ratio test 2 inactive lever presses0.20.61.91.31.41.31.20.7-0.6-0.9-0.7-0.70.6-0.6-0.6-0.50.50.5-0.50.30.20.0
Incentive Sensitization - Responses0.71.83.01.51.71.71.61.4-1.3-1.3-1.4-1.41.3-1.3-1.3-1.31.31.3-1.31.21.20.0
Incentive Sensitization - Breakpoint0.71.72.91.51.71.71.61.3-1.3-1.3-1.3-1.31.3-1.3-1.2-1.21.21.2-1.21.21.10.0
Sum of active levers in priming session hrs 5-60.30.30.5-0.7-0.5-0.7-0.7-0.50.50.60.50.5-0.50.50.50.5-0.4-0.40.4-0.4-0.40.0
Progressive ratio0.51.41.7-1.1-1.2-1.0-1.0-1.21.31.11.21.2-1.31.21.31.2-1.2-1.21.3-1.2-1.20.0
Food seeking constrained by brief footshock5.06.26.9-2.6-2.5-2.4-2.4-2.62.62.62.62.6-2.62.62.62.6-2.5-2.52.6-2.6-2.60.0
Seeking ratio, punishment vs. effort0.40.81.0-0.9-0.9-1.0-1.0-0.90.91.00.91.0-0.90.90.91.0-0.9-0.90.9-1.0-1.00.0
Retroperitoneal fat weight0.00.10.20.40.30.40.40.4-0.4-0.5-0.4-0.40.3-0.3-0.3-0.40.30.3-0.30.30.30.0
Reaction time number correct1.86.48.32.22.22.32.22.6-2.7-2.3-2.7-2.62.7-2.7-2.7-2.72.82.8-2.72.92.90.0
Reaction time mean minus median0.10.52.0-1.4-1.4-0.9-1.0-0.60.60.90.60.7-0.50.50.50.4-0.3-0.30.3-0.2-0.20.0
Reaction time mean minus median AUC0.00.10.4-0.7-0.6-0.2-0.20.1-0.20.1-0.1-0.10.2-0.2-0.2-0.30.40.4-0.40.50.50.0
Reaction time num false alarms3.86.58.72.92.92.82.92.6-2.6-2.8-2.6-2.62.6-2.6-2.5-2.52.52.5-2.42.32.30.0
Reaction time num false alarms AUC2.55.68.02.82.82.62.62.4-2.4-2.5-2.4-2.52.4-2.4-2.4-2.32.32.3-2.22.22.20.0
Reaction time trials correct on left1.86.48.32.22.22.32.22.6-2.7-2.3-2.7-2.62.7-2.7-2.7-2.72.82.8-2.72.92.90.0
Reaction time trials on left1.96.48.32.22.22.32.22.6-2.7-2.3-2.6-2.62.7-2.7-2.7-2.72.72.7-2.72.82.90.0
Reaction time mean1.02.23.6-1.8-1.9-1.6-1.7-1.51.51.61.51.5-1.51.51.51.5-1.4-1.41.3-1.4-1.30.0
Reaction time mean AUC0.71.73.0-1.6-1.7-1.5-1.5-1.31.31.51.31.3-1.31.31.31.3-1.2-1.21.1-1.2-1.20.0
Median of all reaction times1.52.33.0-1.6-1.7-1.6-1.6-1.61.61.61.61.6-1.51.61.51.6-1.5-1.51.5-1.6-1.60.0
Reaction time omissions0.00.00.00.10.10.00.00.0-0.0-0.1-0.0-0.00.0-0.0-0.00.0-0.1-0.1-0.0-0.1-0.10.0
Reaction time false alarm rate0.30.41.11.01.00.80.90.6-0.5-0.8-0.5-0.60.5-0.5-0.5-0.40.40.4-0.40.30.20.0
Reaction time premature initiation rate0.40.61.2-0.5-0.5-0.8-0.7-0.70.71.10.70.7-0.80.80.80.8-0.8-0.80.8-0.8-0.90.0
Reaction time premature initiations0.10.30.40.50.50.40.30.6-0.6-0.0-0.6-0.60.6-0.6-0.6-0.60.60.6-0.50.60.60.0
Std. dev. reaction times0.20.61.8-1.3-1.3-1.0-1.0-0.80.70.90.70.8-0.70.70.70.6-0.5-0.50.5-0.5-0.40.0
Reaction time trials completed1.96.48.32.22.22.32.22.6-2.7-2.3-2.6-2.62.7-2.7-2.7-2.72.72.7-2.72.82.90.0
Reaction time trials AUC2.27.89.92.52.52.62.52.9-2.9-2.6-2.9-2.93.0-3.0-3.0-3.03.03.0-3.03.13.10.0
Run reversals in cocaine runway, females0.20.20.3-0.3-0.5-0.4-0.4-0.50.50.50.50.5-0.50.50.50.6-0.5-0.50.5-0.6-0.60.0
Run reversals in cocaine runway, males0.40.40.50.60.70.60.60.7-0.7-0.7-0.7-0.70.7-0.7-0.7-0.70.70.7-0.70.70.70.0
Latency to leave start box in cocaine runway0.10.10.5-0.3-0.4-0.4-0.50.0-0.10.7-0.10.00.1-0.1-0.1-0.10.20.2-0.30.30.30.0
Latency to leave start box in cocaine runway, F0.40.51.00.30.10.20.10.7-0.70.3-0.7-0.60.7-0.8-0.8-0.80.90.9-1.01.01.00.0
Latency to leave start box in cocaine runway, M0.20.10.2-0.4-0.3-0.4-0.4-0.40.40.30.40.4-0.40.40.40.4-0.4-0.40.4-0.4-0.40.0
Std. dev. time between licks in bursts0.00.00.20.40.40.20.20.2-0.2-0.2-0.2-0.20.1-0.1-0.1-0.1-0.1-0.10.0-0.0-0.10.0
Total sessions with >9 infusions3.74.65.62.22.32.32.42.2-2.2-2.2-2.2-2.22.2-2.2-2.2-2.22.12.1-2.12.12.10.0
Short access day 1 total inactive lever presses0.71.44.12.01.81.71.71.1-1.0-1.3-1.1-1.11.0-1.0-0.9-0.90.80.8-0.80.60.50.0
Short access day 10 total inactive lever presses0.21.21.4-1.1-1.1-1.0-1.1-1.21.20.91.21.1-1.21.21.21.2-1.1-1.11.1-1.2-1.20.0
Short access day 1 total infusions1.42.73.61.81.91.91.81.7-1.7-1.6-1.7-1.71.7-1.7-1.7-1.71.61.6-1.61.61.60.0
Short access day 10 total infusions2.94.86.12.52.42.52.42.3-2.2-2.2-2.2-2.22.2-2.2-2.2-2.22.12.1-2.12.12.10.0
Short access total infusions2.23.24.52.12.12.12.11.8-1.8-1.9-1.8-1.81.8-1.8-1.8-1.71.71.7-1.71.61.60.0
Short access day 1 locomotion2.84.67.62.52.52.72.82.2-2.1-2.4-2.1-2.22.1-2.1-2.1-2.12.02.0-2.01.91.90.0
Short access day 10 total locomotion0.00.00.0-0.2-0.2-0.1-0.0-0.0-0.0-0.0-0.00.00.0-0.0-0.0-0.00.00.0-0.00.10.10.0
Short access total locomotion0.71.01.71.21.11.31.31.0-1.0-1.1-1.0-1.01.0-1.0-1.0-1.00.90.9-0.90.90.90.0
One hour access (0.3 mA shock)0.10.10.20.40.40.30.30.2-0.2-0.4-0.2-0.20.2-0.2-0.2-0.20.20.2-0.20.10.10.0
Compulsive drug intake0.10.10.30.10.0-0.0-0.30.3-0.4-0.2-0.4-0.30.4-0.4-0.4-0.40.50.5-0.50.50.50.0
One hour access (shock baseline)0.61.73.31.51.51.71.81.3-1.2-1.6-1.2-1.31.2-1.2-1.2-1.21.11.1-1.11.11.10.0
Social response proportion0.70.81.10.80.80.80.80.9-1.0-1.0-1.0-0.91.0-1.0-1.0-1.00.90.9-1.01.01.00.0
Social responses0.70.91.11.00.90.90.91.0-1.0-1.0-1.0-1.01.0-1.0-1.0-1.01.01.0-1.01.01.00.0
Social time2.84.46.1-1.7-1.8-2.4-2.4-2.12.12.52.12.1-2.12.12.22.2-2.2-2.22.1-2.2-2.20.0
Soleus weight0.10.40.60.80.70.70.60.6-0.6-0.6-0.6-0.60.6-0.6-0.6-0.60.60.6-0.60.50.50.0
Bone: stiffness0.71.21.51.21.11.11.11.1-1.1-1.0-1.1-1.11.1-1.1-1.1-1.11.21.2-1.21.11.10.0
Tibialis anterior weight3.211.113.73.73.63.63.53.4-3.4-3.4-3.4-3.43.4-3.4-3.4-3.33.43.4-3.43.23.20.0
Time to tail flick, vehicle, before self-admin2.42.93.51.81.91.61.71.8-1.8-1.6-1.8-1.81.8-1.8-1.8-1.81.81.8-1.81.81.80.0
Time to tail flick, vehicle, after self-admin0.00.10.3-0.5-0.6-0.5-0.6-0.00.00.40.00.10.0-0.0-0.0-0.10.10.1-0.00.30.30.0
Time to tail flick, test, before self-admin0.30.30.5-0.7-0.7-0.3-0.2-0.60.60.30.60.6-0.60.60.60.6-0.7-0.70.6-0.6-0.60.0
Time to tail flick, test, after self-admin0.10.20.50.3-0.0-0.2-0.1-0.30.30.70.30.3-0.40.40.40.4-0.5-0.50.6-0.5-0.50.0
Delta time to tail flick, vehicle, before/after SA0.30.31.0-0.8-0.9-0.9-1.0-0.40.40.60.40.4-0.40.40.40.3-0.4-0.40.4-0.2-0.20.0
Delta time to tail flick, test, before/after SA0.60.81.81.31.10.70.80.9-0.9-0.5-0.9-0.90.9-0.9-0.9-0.90.90.9-0.90.90.90.0
Tibia length0.20.61.51.11.00.91.20.9-0.8-0.9-0.8-0.80.8-0.7-0.8-0.70.60.6-0.60.60.60.0
Ambulatory time before self-admin0.00.00.2-0.3-0.3-0.3-0.1-0.10.10.40.10.1-0.10.10.10.1-0.1-0.10.1-0.0-0.00.0
Ambulatory time after self-admin0.40.61.5-0.8-0.8-0.9-0.8-0.80.81.20.80.8-0.80.70.70.7-0.7-0.70.6-0.7-0.70.0
Bone: tissue strength0.80.80.9-0.9-0.9-0.9-0.9-0.90.90.90.90.9-0.90.90.91.0-0.9-0.90.9-1.0-1.00.0
Total heroin consumption0.00.00.10.20.3-0.2-0.1-0.00.0-0.20.00.0-0.00.10.10.1-0.1-0.10.1-0.2-0.20.0
Bone: trabecular number0.00.10.2-0.1-0.10.00.0-0.20.20.10.20.2-0.20.20.20.3-0.5-0.50.4-0.3-0.40.0
Bone: trabecular spacing0.00.00.10.10.1-0.0-0.10.2-0.20.0-0.2-0.20.2-0.2-0.2-0.20.40.4-0.30.30.30.0
Bone: trabecular thickness1.21.72.11.41.41.41.51.4-1.4-1.4-1.3-1.31.4-1.3-1.4-1.31.21.2-1.21.31.30.0
Bone: trabecular tissue density0.20.40.50.50.60.50.60.7-0.7-0.5-0.7-0.70.7-0.6-0.7-0.70.60.6-0.70.70.70.0
Water consumed over 24 hours0.10.20.4-0.7-0.5-0.6-0.6-0.50.50.50.50.5-0.50.50.50.5-0.5-0.50.5-0.4-0.40.0
Number of responses in last shaping day2.43.14.71.51.51.81.91.8-1.8-2.2-1.8-1.81.8-1.8-1.8-1.81.81.8-1.81.91.90.0