Hub : Genes

Ddx5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio XM_039085631.1 0.06 0.03 2.0e-05 0.04 0.04 0.04 0.04 1.8e-04 1.0e-04 2.7e-04 2.4e-04
2 NAcc alternative polyA XM_008768313.3 0.03 0.02 1.3e-03 0.02 0.02 0.01 0.01 1.2e-03 1.5e-03 2.5e-02 8.1e-03
3 Brain isoform ratio NM_001007613.1 0.08 0.04 2.8e-07 0.06 0.06 0.06 0.07 1.4e-06 3.2e-06 7.2e-06 8.7e-07
4 NAcc alternative polyA NM_001007613.1 0.04 0.02 3.5e-04 0.03 0.02 0.02 0.02 2.9e-04 1.3e-03 4.7e-03 9.2e-04
5 NAcc isoform ratio NM_001007613.1 0.02 0.01 8.3e-03 0.01 0.01 0 0.01 4.2e-02 4.0e-02 1.5e-01 5.7e-02
6 Brain alternative polyA NM_001007613.1 0.06 0.03 6.6e-06 0.05 0.05 0.05 0.05 9.2e-06 1.9e-05 2.7e-05 1.1e-05
7 Brain alternative polyA XM_008768313.3 0.06 0.03 1.8e-06 0.06 0.06 0.06 0.06 1.5e-06 3.4e-06 6.9e-06 3.7e-06
8 PL alternative polyA XM_008768313.3 0.03 0.02 4.1e-03 0.02 0.02 0.01 0.01 2.5e-03 6.8e-03 8.9e-03 4.3e-02
9 Adipose mRNA stability Ddx5 0.06 0.03 1.4e-09 0.07 0.08 0.08 0.08 1.3e-08 8.3e-09 1.4e-09 2.0e-09
10 Adipose alternative polyA XM_008768313.3 0.06 0.03 1.5e-04 0.02 0.02 0.02 0.02 1.1e-03 1.3e-03 5.0e-03 1.1e-03
11 Adipose isoform ratio NM_001007613.1 0.06 0.03 6.2e-05 0.03 0.02 0.02 0.03 6.0e-04 2.0e-03 9.7e-04 2.4e-04
12 Adipose isoform ratio XM_008768313.3 0.03 0.02 2.3e-03 0.02 0.01 0 0.01 2.4e-03 2.8e-02 1.6e-01 7.0e-02
13 pVTA alternative polyA XM_008768313.3 0.08 0.05 6.1e-03 0.05 0.05 0.04 0.04 3.8e-03 3.6e-03 5.3e-03 8.2e-03
14 Adipose alternative polyA NM_001007613.1 0.06 0.04 8.6e-05 0.03 0.03 0.02 0.02 7.3e-04 6.0e-04 2.1e-03 1.0e-03
15 Liver isoform ratio XM_039085631.1 0.05 0.03 4.0e-04 0.03 0.03 0.03 0.03 9.2e-05 1.9e-04 1.7e-04 4.8e-04
16 Liver isoform ratio NM_001007613.1 0.04 0.03 1.4e-03 0.03 0.03 0.03 0.03 2.1e-04 2.2e-04 1.2e-04 4.9e-04
17 BLA mRNA stability Ddx5 0.05 0.03 4.6e-03 0.07 0.04 0.03 0.05 1.9e-04 3.3e-03 1.1e-02 1.2e-03
18 Adipose alternative TSS XM_008768313.3 0.03 0.02 5.1e-03 0 0.01 0 0 2.7e-01 7.6e-03 7.4e-02 1.1e-01
19 Liver alternative polyA NM_001007613.1 0.04 0.02 2.0e-03 0.01 0.03 0.02 0.02 1.2e-02 8.2e-04 1.1e-03 2.4e-03
20 Liver alternative polyA XM_008768313.3 0.05 0.03 8.7e-04 0.01 0.03 0.03 0.02 6.8e-03 5.6e-04 6.7e-04 1.2e-03
21 NAcc mRNA stability Ddx5 0.05 0.03 1.3e-05 0.04 0.04 0.03 0.04 2.5e-05 9.2e-06 1.5e-04 4.3e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.91.53.7-1.71.91.9-1.91.4-1.31.31.1-1.51.31.10.4-1.11.30.9-1.0-1.20.10.3-0.50.4
Area under the delay curve0.20.20.9-0.60.30.2-0.2-0.10.1-0.10.00.1-0.4-0.5-0.10.3-0.6-0.40.4-0.10.3-0.90.9-0.2
BMI with tail0.51.89.5-1.8-0.30.70.3-0.5-0.70.70.60.20.1-0.1-0.11.5-1.9-1.31.31.1-0.5-3.13.1-1.1
BMI without tail1.32.710.4-3.20.92.0-0.90.9-2.12.12.1-1.01.21.11.20.3-1.0-0.30.50.1-1.4-2.92.9-0.4
Body weight1.66.920.0-4.53.13.7-3.12.8-3.43.43.6-2.93.02.92.5-1.71.31.2-1.2-1.1-1.4-1.71.60.2
Weight adjusted by age1.01.11.80.9-1.2-1.11.2-1.11.2-1.2-1.11.2-1.3-1.3-0.70.9-1.2-1.11.11.00.5-0.80.9-0.7
Bone surface5.810.216.1-3.34.03.8-3.93.7-3.43.43.2-3.83.63.62.3-3.54.03.2-3.1-2.9-0.51.7-2.01.3
Bone volume4.27.112.0-3.13.53.4-3.43.1-2.92.92.8-3.23.02.91.9-2.73.02.5-2.4-2.5-0.50.9-1.21.0
Breakpoint value in progressive ratio session0.40.42.0-0.30.80.3-0.80.8-0.30.30.4-0.60.70.81.4-1.00.80.2-0.20.8-0.60.0-0.1-0.0
Number of licking bursts0.00.10.40.20.0-0.10.00.10.2-0.2-0.00.10.00.1-0.0-0.20.5-0.00.00.20.60.1-0.2-0.4
Context. condit. distance diff. score0.00.10.20.1-0.4-0.40.5-0.20.2-0.2-0.10.2-0.1-0.10.00.2-0.0-0.30.1-0.1-0.1-0.20.2-0.4
Locomotion velocity, session 10.80.82.7-1.31.61.4-1.61.0-1.01.00.8-1.10.90.90.6-0.70.80.5-0.5-0.1-0.0-0.1-0.00.2
Locomotion distance, session 10.30.41.6-1.30.60.9-0.60.3-0.90.90.7-0.40.40.4-0.20.20.1-0.20.2-0.10.5-1.11.0-0.6
Locomotion velocity, session 20.70.82.7-0.31.00.5-1.01.2-0.80.80.7-0.91.31.41.2-1.21.60.6-0.60.5-0.10.6-0.7-0.2
Locomotion distance, session 20.20.31.2-0.50.50.2-0.50.4-0.30.30.2-0.10.30.40.2-0.10.7-0.40.41.00.8-0.80.7-1.1
Locomotion velocity, session 31.01.23.80.1-0.3-0.70.3-0.70.8-0.8-0.70.8-0.6-0.6-0.81.0-0.4-1.51.41.91.4-1.61.5-1.9
Locomotion distance, session 30.10.10.8-0.20.40.0-0.30.2-0.10.10.3-0.10.30.3-0.0-0.10.7-0.20.10.50.9-0.30.1-0.9
Stereotopy head waving bouts, day 30.70.81.60.5-0.5-0.60.5-1.01.0-1.0-1.10.9-1.2-1.3-1.11.1-1.2-1.11.01.00.6-0.80.7-0.4
Stereotopy head waving duration, day 30.81.01.60.4-0.6-0.80.7-1.01.1-1.1-1.21.0-1.2-1.3-0.91.0-1.2-1.21.11.20.7-1.11.1-0.8
Locomotion velocity, session 70.10.10.40.5-0.4-0.30.3-0.40.2-0.2-0.30.2-0.1-0.2-0.60.4-0.0-0.2-0.00.20.40.4-0.4-0.1
Locomotion distance, session 70.00.00.2-0.0-0.4-0.10.4-0.0-0.30.30.20.10.00.10.3-0.0-0.00.1-0.1-0.3-0.2-0.20.3-0.0
Stereotopy head waving bouts, day 71.01.13.50.7-0.2-0.90.3-0.81.3-1.3-1.21.0-1.0-1.0-0.70.9-0.6-1.41.41.91.2-1.00.9-1.4
Stereotopy head waving duration, day 72.32.76.11.9-0.8-1.80.9-1.52.3-2.3-2.31.7-1.7-1.7-1.31.2-0.7-1.81.72.51.9-0.60.5-1.7
Locomotion velocity, session 81.01.22.1-0.61.21.0-1.31.3-1.01.01.1-1.31.41.40.9-1.31.51.1-1.3-0.7-0.51.1-1.20.7
Locomotion distance, session 80.10.10.3-0.40.30.1-0.20.4-0.30.30.5-0.30.50.50.5-0.30.6-0.1-0.00.0-0.0-0.30.3-0.5
Degree of sensitization distance0.30.31.2-0.5-0.00.50.00.4-0.70.70.5-0.40.20.20.6-0.5-0.10.7-0.7-1.1-1.10.3-0.21.1
Degree of sensitization stereotypy1.51.65.11.1-0.5-1.30.5-0.91.5-1.5-1.41.2-1.0-0.9-0.81.0-0.3-1.61.62.31.6-1.00.9-1.9
Conditioned locomotion0.30.31.9-0.40.30.3-0.40.5-0.50.50.6-0.40.30.31.1-0.6-0.30.4-0.4-0.4-1.4-0.10.20.8
Cocaine response after cond. corrected0.40.41.00.8-0.4-0.70.4-0.70.8-0.8-1.00.6-0.9-0.9-0.80.4-0.2-0.30.30.51.00.2-0.2-0.1
Cocaine response after cond. not corrected0.80.93.01.4-0.1-1.00.2-0.71.3-1.3-1.40.7-1.0-0.9-0.90.20.5-0.50.40.91.70.6-0.7-0.7
Cocaine response before conditioning0.30.41.70.50.3-0.5-0.2-0.10.8-0.8-0.70.3-0.2-0.1-0.30.10.7-0.70.60.81.2-0.20.1-1.3
Saline control response0.60.84.1-1.00.90.7-0.90.9-0.60.60.7-0.60.60.71.9-0.7-0.40.00.10.3-2.0-1.01.00.4
Bone: connectivity density1.82.84.9-1.92.22.2-2.21.9-1.81.81.5-2.01.81.71.0-1.72.01.6-1.6-1.5-0.20.8-0.90.8
Bone: cortical apparent density4.15.510.11.2-2.7-2.02.7-2.81.9-1.9-1.92.5-2.3-2.5-2.93.2-2.9-2.62.51.51.6-2.22.3-1.9
Bone: cortical area1.72.58.7-3.02.02.2-1.81.5-2.02.02.0-1.61.91.70.7-0.51.10.2-0.3-0.90.3-1.71.5-1.1
Bone: cortical porosity4.85.213.0-1.73.62.3-3.63.0-1.71.71.7-2.62.62.62.9-2.93.01.5-1.7-0.7-1.01.2-1.40.8
Bone: cortical porosity2.52.78.4-1.72.91.9-2.92.2-1.31.31.2-1.91.91.92.0-1.92.20.6-0.8-0.3-0.20.0-0.3-0.2
Bone: cortical thickness5.59.018.70.3-1.9-1.72.0-3.01.9-1.9-2.02.7-2.3-2.5-3.54.1-3.1-4.03.92.83.1-4.34.2-4.0
Bone: cortical thickness3.33.88.10.8-1.8-1.51.8-2.01.4-1.4-1.42.0-1.4-1.4-2.42.7-1.5-2.52.41.42.3-2.22.2-2.8
Bone: cortical tissue density3.95.29.51.3-2.7-2.02.7-2.81.9-1.9-1.92.5-2.3-2.5-2.83.1-2.8-2.52.41.41.4-2.02.1-1.7
Condit. Reinf. active minus inactive responses1.31.44.4-1.41.81.3-1.81.6-1.01.01.0-1.31.21.32.1-1.51.00.5-0.5-0.7-1.2-0.30.30.3
Condit. Reinf. active-inactive response ratio0.50.51.9-0.51.20.6-1.11.0-0.30.30.4-0.70.60.61.4-1.10.90.5-0.4-0.5-0.70.2-0.30.3
Condit. Reinf. active responses1.92.35.7-1.92.11.7-2.11.9-1.41.41.5-1.61.51.62.4-1.81.10.7-0.8-1.2-1.5-0.40.30.5
Condit. Reinf. inactive responses1.01.12.6-1.61.31.4-1.21.2-1.41.41.4-1.21.11.11.0-0.90.60.6-0.6-1.2-0.6-0.40.40.3
Incentive salience index mean1.31.64.7-1.32.21.4-2.11.7-0.90.91.0-1.41.31.41.9-1.61.30.5-0.6-0.5-0.8-0.1-0.00.2
Condit. Reinf. lever presses0.20.31.6-0.21.30.3-1.30.60.3-0.30.0-0.30.20.30.8-0.60.4-0.40.30.40.0-0.30.2-0.3
Condit. Reinf. active minus inactive responses3.84.711.1-2.93.32.5-3.12.8-2.12.12.1-2.42.32.42.7-2.52.81.1-1.1-0.9-0.2-0.60.3-0.5
Condit. Reinf. active-inactive response ratio1.92.06.1-1.32.51.6-2.41.9-1.01.00.9-1.61.31.31.9-2.01.90.9-0.9-0.5-0.30.4-0.60.3
Condit. Reinf. active responses4.36.010.9-3.33.32.8-3.13.1-2.72.72.7-2.72.72.83.2-2.72.51.4-1.4-1.6-1.3-0.60.40.1
Condit. Reinf. inactive responses2.02.46.0-2.41.31.7-1.11.6-2.12.12.3-1.51.81.92.0-1.00.70.6-0.6-1.3-1.5-1.31.3-0.1
Condit. Reinf. lever presses1.21.73.2-1.81.81.4-1.71.6-1.31.31.4-1.31.51.61.8-1.11.20.2-0.2-0.6-0.6-0.90.8-0.6
Condit. Reinf. lever reinforcers received3.65.19.2-3.03.02.6-2.82.8-2.52.52.6-2.52.52.62.9-2.52.31.4-1.4-1.6-1.2-0.50.40.2
Conditioned reinforcement - actives0.20.20.6-0.80.80.8-0.60.6-0.30.30.5-0.40.20.30.8-0.4-0.1-0.10.10.4-0.6-0.60.60.1
Conditioned reinforcement - inactives1.82.04.3-1.91.31.8-1.51.5-2.12.11.9-1.61.91.80.9-1.01.21.1-1.2-1.0-0.70.1-0.20.5
Conditioned locomotion1.72.14.4-2.11.82.0-1.81.7-1.71.71.7-1.61.51.41.4-1.30.70.8-0.9-1.2-1.3-0.30.20.9
Patch foraging indifference point 0 sec3.55.713.5-3.72.63.1-2.52.6-3.13.13.1-2.62.62.62.6-1.91.31.5-1.3-2.2-1.8-1.11.00.6
Patch foraging indifference point AUC1.31.52.9-1.71.11.4-1.01.4-1.51.51.7-1.51.61.51.1-1.10.90.9-1.0-0.9-1.10.0-0.10.6
Delay disc. indifference point, 0s delay0.60.61.10.8-1.1-0.91.0-0.90.8-0.8-0.70.9-1.0-1.1-1.00.7-0.8-0.60.60.30.6-0.30.3-0.3
Delay disc. indifference point, 16s delay0.40.42.3-0.80.20.3-0.2-0.20.1-0.1-0.00.2-0.5-0.60.20.4-1.0-0.70.70.2-0.1-1.51.5-0.3
Delay disc. indifference point, 2s delay0.40.51.6-1.21.00.9-0.80.7-0.70.70.8-0.80.40.30.1-0.60.60.5-0.5-1.30.5-0.20.10.2
Delay disc. indifference point, 24s delay1.21.24.7-2.21.31.5-1.20.9-1.21.21.3-0.90.70.51.0-0.3-0.40.0-0.0-0.7-0.8-1.61.60.1
Delay disc. indifference point, 4s delay0.70.71.40.8-0.6-0.90.6-0.91.1-1.1-1.00.9-1.1-1.1-1.00.7-0.5-0.90.90.61.2-0.30.3-0.7
Delay disc. indifference point, 8s delay0.50.51.3-0.1-0.2-0.20.3-0.70.5-0.5-0.50.6-0.9-1.0-0.60.8-1.1-0.80.80.30.5-1.11.1-0.4
Indifference point function ln k0.71.02.30.4-0.4-0.70.5-0.90.9-0.9-1.11.0-0.9-0.9-0.81.1-0.8-1.31.40.51.2-1.41.4-1.5
Indifference point function log k0.71.02.30.4-0.4-0.70.5-0.90.9-0.9-1.11.0-0.9-0.9-0.81.1-0.8-1.31.40.51.2-1.41.4-1.5
Patch foraging total patch changes 0 sec3.75.913.7-3.72.73.1-2.62.7-3.23.23.1-2.62.72.72.6-2.01.41.6-1.4-2.3-1.9-1.00.90.8
Patch foraging total patch changes 12 sec5.47.010.8-3.12.63.0-2.53.1-3.33.33.3-3.02.92.93.0-2.82.02.4-2.3-2.6-2.40.5-0.51.8
Patch foraging total patch changes 18 sec2.53.25.7-2.41.82.0-1.72.1-2.32.32.4-2.02.12.22.2-1.71.31.3-1.2-1.1-1.7-0.30.30.7
Patch foraging total patch changes 24 sec3.44.211.2-3.32.32.7-2.22.3-2.72.72.8-2.22.22.12.1-1.51.21.0-1.0-1.7-1.2-1.11.00.3
Patch foraging total patch changes 6 sec2.63.98.1-2.82.02.5-1.92.2-2.72.72.6-2.32.52.51.8-1.61.61.4-1.4-1.8-1.2-0.30.20.5
Patch foraging time to switch 0 sec0.30.41.71.3-0.5-0.80.4-0.40.7-0.7-0.70.5-0.6-0.5-0.20.1-0.20.0-0.00.9-0.11.1-1.00.6
Patch foraging water rate 0 sec1.52.56.5-2.51.62.2-1.61.5-2.22.22.1-1.71.81.71.1-0.80.61.0-0.9-1.8-1.1-0.70.70.5
Patch foraging water rate 12 sec0.91.44.20.2-0.8-0.70.9-1.20.7-0.7-0.81.1-0.8-0.9-1.71.6-0.6-1.31.40.72.1-1.51.4-2.0
Patch foraging water rate 18 sec0.40.62.7-0.60.50.2-0.4-0.30.1-0.1-0.20.2-0.2-0.2-0.60.60.2-0.80.90.21.6-1.41.2-1.6
Patch foraging water rate 24 sec0.10.21.3-0.00.40.0-0.3-0.10.2-0.2-0.40.2-0.3-0.2-0.30.20.2-0.30.40.41.1-0.60.5-0.9
Patch foraging water rate 6 sec0.40.51.9-0.40.10.0-0.0-0.60.2-0.2-0.30.4-0.5-0.5-0.80.9-0.6-0.80.90.41.1-1.41.3-1.1
Seeking ratio, delayed vs. immediate footshock0.10.10.6-0.40.10.2-0.1-0.0-0.10.10.3-0.0-0.0-0.00.60.3-0.8-0.30.30.1-0.8-0.60.70.2
Distance traveled before self-admin0.70.72.11.1-0.6-1.10.7-0.61.2-1.2-1.20.9-0.8-0.8-0.70.20.4-0.50.51.21.40.1-0.2-1.0
Distance traveled after self-admin0.30.41.20.8-0.3-0.80.3-0.10.8-0.8-0.80.5-0.2-0.10.2-0.20.8-0.40.41.01.00.0-0.1-1.1
Extensor digitorum longus weight1.24.617.22.2-3.3-2.13.1-2.71.7-1.7-1.62.1-2.4-2.6-1.72.5-4.1-0.91.0-0.0-1.8-0.00.41.7
Bone: elastic displacement2.02.24.30.9-0.7-1.10.7-1.51.6-1.6-1.51.4-1.4-1.5-1.91.7-0.9-2.11.81.72.0-1.31.2-1.9
Bone: elastic work0.20.30.7-0.80.70.8-0.80.0-0.30.30.4-0.30.40.2-0.70.50.0-0.60.3-0.00.8-0.70.5-0.7
Bone: endosteal estimation15.233.146.6-4.96.05.9-6.06.8-5.95.95.8-6.46.46.66.2-6.86.46.2-6.0-5.3-3.93.7-4.03.9
Bone: endosteal perimeter15.832.946.5-5.56.46.2-6.26.8-6.16.16.0-6.66.46.56.1-6.76.35.8-5.8-5.1-3.53.0-3.33.5
Epididymis fat weight0.82.04.1-1.91.01.9-1.11.1-1.91.91.9-1.51.21.11.1-0.7-0.31.4-1.3-1.2-2.00.00.01.8
Delta time in closed arm before/after self-admin0.40.31.30.10.70.3-0.90.5-0.20.20.1-0.50.40.4-0.1-0.61.10.6-0.6-0.50.61.0-1.10.2
Delta time in open arm before/after self-admin1.11.13.30.6-1.5-0.91.5-1.10.9-0.9-0.71.2-1.2-1.3-0.41.1-1.8-0.90.90.7-0.6-0.91.10.0
Diff in mean of infusions in LGA sessions1.01.22.30.9-1.2-1.11.2-1.21.0-1.0-1.21.2-1.0-1.0-0.91.2-1.2-1.21.21.50.5-0.80.9-0.9
Delay discount exponential model param0.10.10.60.8-0.6-0.50.5-0.20.2-0.2-0.30.20.10.2-0.10.10.30.1-0.10.5-0.10.7-0.6-0.1
Extinction: sum of active levers before priming0.10.10.7-0.4-0.10.10.30.2-0.20.20.4-0.10.1-0.00.6-0.2-0.4-0.20.1-0.2-0.8-0.50.60.2
Active lever presses in extinction session 61.21.22.8-1.21.11.2-0.81.3-1.21.21.4-1.21.31.31.7-1.20.70.7-0.8-0.6-1.40.1-0.10.8
Bone: final force1.11.84.6-2.21.51.7-1.41.3-1.71.71.6-1.41.71.60.2-0.71.80.7-0.7-1.51.0-0.50.3-0.9
Bone: final moment1.22.04.7-2.21.61.8-1.51.4-1.81.81.6-1.51.81.70.2-0.71.90.8-0.8-1.51.0-0.40.2-0.9
Food consumed during 24 hour testing period2.22.75.0-2.22.12.2-2.11.8-2.02.02.0-1.91.71.62.1-1.30.51.1-1.1-0.6-1.8-0.30.21.2
Glucose0.81.22.11.3-1.2-1.41.3-1.21.2-1.2-1.11.2-1.0-1.0-1.01.0-0.6-1.01.01.51.1-0.30.3-1.0
Heart weight0.50.72.5-0.2-0.1-0.30.3-0.50.5-0.5-0.30.7-0.8-0.8-0.20.7-0.8-1.21.20.30.6-1.61.6-1.1
Delay discount hyperbolic model param0.10.10.50.7-0.5-0.40.4-0.10.1-0.1-0.20.10.20.30.1-0.00.40.2-0.20.4-0.20.7-0.70.0
Intermittent access intake day 1-15 change1.11.13.90.50.40.3-0.60.7-0.30.30.4-0.80.60.60.7-1.10.81.4-1.4-1.3-1.22.0-1.91.7
Intermittent access intake escalation0.60.62.60.70.2-0.1-0.20.3-0.00.00.1-0.40.20.20.3-0.60.41.0-0.9-1.0-0.81.6-1.51.3
Intermittent access intake escalation 21.91.95.1-0.00.60.7-0.71.1-1.01.00.9-1.31.11.10.9-1.41.11.9-1.9-2.0-1.42.3-2.22.0
Intermitt. access day 1 inactive lever presses3.63.97.4-2.52.62.3-2.72.4-2.22.22.2-2.22.52.62.3-2.12.11.1-1.1-0.4-0.9-0.50.3-0.1
Intermitt. access day 15 inactive lever presses1.51.73.9-1.21.31.6-1.71.3-1.51.51.2-1.51.51.41.7-1.10.41.0-1.1-0.7-2.00.3-0.31.3
Intermitt. access escalation Index2.62.35.92.1-1.4-2.11.2-1.51.9-1.9-2.41.5-1.4-1.5-1.61.0-0.1-1.21.11.52.10.1-0.1-1.5
Intermittent access day 1 total infusions0.60.72.8-1.70.91.2-0.70.6-0.90.90.9-0.60.60.60.6-0.10.0-0.40.40.50.1-1.61.5-0.7
Intermittent access day 15 total infusions0.30.30.8-0.80.70.9-0.70.6-0.60.60.7-0.60.50.50.6-0.50.10.4-0.4-0.5-0.7-0.00.00.6
Intermittent access terminal intake (last 3 days)2.22.43.8-1.71.52.0-1.41.7-1.91.91.7-1.81.71.71.5-1.51.01.5-1.5-1.4-1.50.6-0.61.3
Intermittent access total infusions2.12.45.3-2.31.92.2-1.81.8-2.02.01.9-1.71.81.81.6-1.31.00.9-0.9-0.8-1.0-0.50.40.5
Intermittent access day 1 locomotion2.42.57.2-2.72.12.4-1.81.9-2.02.01.9-1.81.81.71.5-1.20.90.5-0.6-0.6-0.8-1.00.80.2
Intermittent access day 15 total locomotion4.75.18.7-2.92.93.0-2.72.7-2.62.62.7-2.72.62.52.3-2.21.81.7-1.6-1.9-1.50.3-0.41.3
Intermittent access total locomotion6.57.415.6-4.03.33.8-3.23.1-3.53.53.4-3.13.23.12.7-2.31.71.5-1.6-2.1-1.9-0.60.41.1
Intermittent access standard deviation1.11.22.3-1.41.11.5-1.01.2-1.41.41.5-1.21.21.21.1-0.80.40.8-0.8-1.1-1.30.2-0.21.0
Left kidney weight1.33.812.0-0.3-0.6-0.80.8-1.41.1-1.1-0.91.6-1.1-1.1-1.62.1-1.0-2.62.72.32.6-3.33.2-3.5
Right kidney weight0.71.87.2-0.50.4-0.1-0.3-0.70.8-0.8-0.40.8-0.6-0.6-1.11.3-0.2-1.71.81.52.4-2.42.2-2.7
Cocaine induced anxiety0.30.30.60.2-0.3-0.30.5-0.60.6-0.6-0.40.6-0.6-0.5-0.80.7-0.5-0.60.60.10.7-0.60.6-0.7
Post-drug Anxiety0.60.61.50.7-0.6-0.60.8-1.01.0-1.0-0.50.9-1.2-1.1-1.00.9-1.0-0.70.70.10.6-0.30.3-0.2
Baseline Anxiety0.91.02.00.9-1.0-1.01.0-1.21.1-1.1-0.91.1-1.4-1.4-1.11.1-1.2-0.90.90.90.7-0.40.5-0.4
Tail length1.75.28.7-2.92.82.9-2.82.7-2.72.72.9-2.62.32.42.5-2.31.71.9-1.8-1.8-1.60.2-0.31.4
Length with tail2.07.513.4-3.03.73.3-3.63.3-2.92.93.2-3.22.93.02.4-3.03.02.4-2.4-2.1-0.81.0-1.21.3
Length without tail0.71.63.5-0.61.81.2-1.71.4-0.80.81.0-1.41.21.10.6-1.61.91.4-1.5-1.00.21.4-1.60.7
Times rat made contact with spout0.80.91.9-0.91.31.2-1.41.1-1.01.00.8-1.11.01.00.9-1.01.00.9-0.9-0.5-0.50.5-0.60.6
Lifetime Intake2.32.77.0-2.61.92.3-1.71.8-2.12.12.1-1.71.91.91.8-1.20.90.6-0.6-0.5-1.0-1.11.00.1
Liver weight, left0.91.43.0-1.21.71.3-1.61.4-1.11.11.2-1.41.21.21.0-1.41.71.0-1.1-0.70.00.6-0.80.3
Liver weight, right0.30.53.1-0.7-0.20.20.3-0.6-0.10.10.10.3-0.3-0.4-1.51.0-0.1-0.50.40.31.8-1.00.8-1.2
Locomotor activity0.91.44.2-1.61.60.9-1.50.9-0.80.80.7-0.51.11.11.1-0.20.8-0.90.90.70.5-2.01.9-1.9
Locomotor testing distance1.11.85.1-1.81.81.1-1.81.2-0.90.90.8-0.81.21.22.1-0.60.4-0.90.90.6-0.7-2.32.2-1.4
Locomotor testing rearing0.81.24.9-0.71.50.9-1.61.5-0.80.80.9-1.01.41.62.2-1.31.00.3-0.20.0-1.4-0.10.10.0
Locomotion in novel chamber0.20.21.40.10.80.1-0.70.30.1-0.1-0.3-0.30.20.2-0.1-0.51.10.2-0.10.31.20.4-0.5-0.5
Locomotion in novel chamber post-restriction2.22.64.4-1.61.31.7-1.11.8-1.91.91.8-1.81.71.80.8-1.92.01.9-2.0-2.1-0.41.1-1.21.0
Fecal boli incidents, locomotor time 10.10.10.40.6-0.5-0.50.4-0.30.5-0.5-0.60.3-0.5-0.50.2-0.1-0.4-0.10.10.1-0.30.2-0.20.4
Change in fecal boli incidents, locomotor task0.20.20.9-0.3-0.60.10.6-0.5-0.20.20.30.3-0.2-0.3-0.50.8-0.9-0.20.2-0.6-0.1-0.50.60.1
Time >=10cm from walls, locomotor time 11.31.34.01.6-1.3-1.61.0-1.11.2-1.2-1.21.2-0.8-0.7-1.40.80.4-0.70.71.52.00.3-0.3-1.5
Bouts of movement, locomotor time 10.40.41.70.5-0.8-0.30.8-0.80.4-0.4-0.40.6-0.7-0.7-0.80.9-1.3-0.40.40.2-0.4-0.20.30.4
Total resting periods, locomotor time 10.30.41.50.5-0.9-0.30.9-0.80.3-0.3-0.30.5-0.7-0.7-1.00.9-1.2-0.20.2-0.0-0.40.10.00.6
Rest time, locomotor task time 10.30.41.11.0-0.8-0.70.8-0.70.7-0.7-0.70.6-0.7-0.7-0.40.3-0.7-0.00.00.1-0.20.6-0.50.6
Distance moved, locomotor task time 10.70.81.7-1.31.31.2-1.31.0-1.01.01.1-1.00.90.90.7-0.60.60.6-0.6-0.3-0.4-0.10.00.3
Vertical activity count, locomotor time 10.40.41.2-0.91.10.9-1.00.8-0.80.80.7-0.80.70.70.5-0.50.80.4-0.4-0.30.2-0.1-0.1-0.1
Time >=10cm from walls, locomotor time 20.40.42.01.00.1-0.4-0.30.00.4-0.4-0.4-0.00.10.2-0.2-0.31.00.4-0.50.70.61.4-1.40.1
Bouts of movement, locomotor time 20.50.62.00.5-1.3-0.61.1-0.90.6-0.6-0.40.8-0.8-0.8-0.60.9-1.4-0.50.50.6-0.6-0.50.60.1
Total resting periods, locomotor time 20.90.92.40.8-1.5-0.91.4-1.20.8-0.8-0.71.1-1.0-1.0-0.91.2-1.6-0.80.80.9-0.3-0.60.8-0.1
Rest time, locomotor task time 24.24.89.82.6-3.1-2.73.1-2.52.4-2.4-2.52.5-2.6-2.6-2.31.9-2.1-1.51.51.81.1-0.20.4-0.6
Distance moved, locomotor task time 21.01.22.5-0.81.61.2-1.51.2-1.11.11.0-1.31.31.30.9-1.01.20.9-1.0-0.4-0.50.8-0.90.6
Vertical activity count, locomotor time 22.73.05.0-1.82.22.0-2.22.1-1.91.91.8-2.02.12.12.1-1.71.51.4-1.3-1.2-1.50.5-0.61.0
Light reinforcement 10.81.48.1-1.30.00.30.1-0.3-0.20.20.30.3-0.3-0.50.40.9-1.8-1.61.50.7-0.6-2.82.8-0.9
Light reinforcement 20.40.62.7-1.30.30.6-0.20.0-0.50.50.7-0.20.0-0.20.40.4-1.3-0.70.5-0.0-0.8-1.71.7-0.0
Bone: marrow area14.932.445.7-4.85.95.8-5.96.7-5.85.85.7-6.46.36.56.1-6.86.46.2-5.9-5.3-3.83.8-4.03.9
Bone: maximum diameter4.58.212.5-3.53.53.4-3.33.4-3.33.33.3-3.43.43.42.6-3.03.32.5-2.4-2.5-0.80.4-0.70.6
Bone: maximum force1.93.410.0-3.22.02.5-1.91.8-2.52.52.4-1.92.12.00.9-1.01.61.0-0.9-2.00.3-1.21.0-0.6
Bone: maximum moment2.03.59.8-3.12.12.6-2.01.9-2.62.62.4-2.02.22.10.8-1.01.71.0-1.0-2.00.2-0.90.7-0.5
Mean time between licks in bursts0.10.10.4-0.60.00.50.00.2-0.60.60.5-0.30.30.2-0.1-0.1-0.00.4-0.4-0.3-0.2-0.10.10.3
Mean num. licks in bursts0.30.31.3-0.80.50.8-0.60.4-0.70.70.4-0.50.30.20.5-0.2-0.50.3-0.3-0.4-1.1-0.20.20.8
Cd content in liver2.32.55.52.4-2.1-2.12.1-1.82.0-2.0-2.01.8-2.0-1.9-1.51.3-1.3-0.80.7-0.00.60.7-0.60.1
Co content in liver0.40.42.01.4-0.5-0.90.5-0.41.0-1.0-0.90.4-0.3-0.4-0.1-0.0-0.0-0.1-0.10.3-0.31.1-1.10.4
Cu content in liver0.20.21.2-0.10.20.2-0.30.2-0.30.30.3-0.30.10.10.5-0.3-0.50.4-0.3-0.3-1.10.3-0.21.0
Fe content in liver0.20.30.80.3-0.8-0.70.8-0.30.3-0.3-0.20.6-0.3-0.1-0.10.4-0.2-0.60.70.30.3-0.70.7-0.9
K content in liver1.01.02.5-0.81.30.9-1.21.3-0.90.90.8-1.21.21.11.0-1.51.60.8-1.0-0.40.10.6-0.80.2
Mg content in liver0.40.41.40.20.10.1-0.10.4-0.30.30.3-0.60.50.40.3-0.80.50.7-0.9-0.6-0.51.2-1.20.9
Mn content in liver0.20.21.4-0.50.50.2-0.40.4-0.10.10.3-0.20.20.3-0.1-0.30.9-0.10.1-0.21.2-0.40.2-0.9
Na content in liver0.30.30.9-0.30.60.0-0.50.60.1-0.1-0.2-0.30.50.50.8-0.70.8-0.50.21.00.3-0.50.4-0.9
Rb content in liver1.31.63.61.8-1.7-1.91.8-1.41.3-1.3-1.41.4-1.1-1.0-1.51.1-0.3-0.90.90.41.60.1-0.1-1.2
Se content in liver1.31.62.61.0-1.1-1.41.2-1.31.4-1.4-1.31.4-1.4-1.4-0.91.1-1.1-1.51.41.61.1-1.11.1-1.3
Sr content in liver0.30.30.8-0.90.80.9-0.80.5-0.60.60.6-0.60.60.60.1-0.30.70.2-0.30.10.4-0.20.1-0.3
Zn content in liver0.20.21.2-0.50.60.2-0.50.00.1-0.1-0.2-0.2-0.0-0.2-0.20.00.3-0.50.30.81.1-0.80.6-0.9
Bone: minimum diameter11.621.630.5-5.45.55.5-5.55.5-5.35.35.2-5.55.35.24.7-4.94.44.2-4.2-4.1-2.91.3-1.62.5
Time in familiar zone, hab. session 11.41.32.9-0.50.60.8-0.71.1-1.11.11.1-1.10.90.91.3-1.30.61.4-1.3-1.7-1.51.2-1.11.7
Time in novel zone, hab. session 11.51.52.60.7-1.2-1.11.2-1.31.1-1.1-1.11.2-1.0-1.1-1.51.6-0.9-1.31.31.61.3-1.11.0-1.5
Total zone transitions, hab. session 10.40.51.6-1.31.01.0-1.00.6-0.90.90.8-0.50.60.70.20.00.3-0.10.20.10.3-1.11.0-0.7
Total locomotion distance, hab. session 11.01.54.5-2.11.71.9-1.71.1-1.61.61.4-1.11.31.30.5-0.30.80.2-0.1-0.00.3-1.21.1-0.7
Locomotion velocity, hab. session 11.31.84.8-2.22.02.1-2.11.4-1.71.71.6-1.41.31.40.8-0.71.00.5-0.4-0.30.1-0.90.8-0.3
Time in familiar zone, hab. session 21.71.83.2-0.81.11.0-1.11.6-1.21.21.4-1.41.51.61.8-1.71.51.3-1.4-1.3-1.31.0-1.11.0
Time in novel zone, hab. session 21.11.13.70.6-1.2-0.71.2-1.30.7-0.7-0.91.1-1.1-1.2-1.91.5-1.1-0.80.90.91.3-0.60.6-0.7
Total zone transitions, hab. session 20.20.20.6-0.70.60.4-0.60.4-0.50.50.4-0.30.50.60.3-0.10.3-0.10.20.80.1-0.70.6-0.6
Total locomotion distance, hab. session 20.60.82.7-1.61.01.4-1.00.8-1.41.41.3-0.90.90.90.5-0.20.10.4-0.3-0.3-0.5-0.80.80.1
Locomotion velocity, hab. session 20.60.82.7-1.61.01.4-1.00.7-1.31.31.3-0.90.80.80.4-0.20.10.4-0.3-0.2-0.4-0.80.80.1
Novel to familiar place preference ratio0.40.50.9-0.90.50.9-0.50.6-1.01.00.9-0.80.90.90.2-0.40.60.6-0.6-0.8-0.20.1-0.20.2
Novelty place preference0.20.20.5-0.60.30.6-0.30.4-0.70.70.6-0.60.70.70.1-0.20.50.4-0.4-0.5-0.10.1-0.1-0.0
Time in novel zone, NPP test0.20.20.5-0.50.20.5-0.20.3-0.60.60.5-0.50.70.6-0.0-0.10.60.3-0.3-0.30.20.0-0.1-0.3
Total zone transitions, NPP test0.60.94.5-1.30.70.6-0.60.1-0.40.40.40.00.00.1-0.10.5-0.2-1.01.00.90.9-2.12.0-1.5
Total locomotion distance, NPP test0.81.23.4-1.81.41.7-1.41.0-1.51.51.5-1.11.11.20.5-0.40.70.4-0.4-0.50.1-0.70.7-0.2
Locomotion velocity, NPP test0.60.93.6-1.91.01.4-1.00.6-1.31.31.3-0.70.60.60.30.1-0.2-0.10.2-0.1-0.1-1.51.5-0.3
Intraocular pressure0.60.83.8-1.20.20.7-0.20.0-0.40.40.70.0-0.2-0.10.70.4-1.5-0.60.61.0-1.3-1.82.00.1
Delta distance traveled before/after self-admin0.30.41.10.2-0.6-0.40.5-0.40.4-0.4-0.40.6-0.2-0.2-0.00.6-0.3-0.90.90.90.3-0.90.9-1.0
Delta ambulatory time before/after self-admin0.10.10.3-0.40.10.2-0.10.2-0.20.20.2-0.10.20.20.4-0.0-0.0-0.20.2-0.0-0.2-0.50.5-0.3
Parametrial fat weight1.12.13.5-1.31.71.9-1.81.2-1.31.31.5-1.71.10.90.5-1.20.91.8-1.8-1.8-0.71.3-1.41.8
Pavlov. Cond. lever latency1.11.45.11.6-2.3-1.42.2-1.50.7-0.7-0.91.2-1.2-1.3-1.41.1-1.30.00.0-0.3-0.10.9-0.60.8
Pavlov. Cond. magazine entry latency2.12.77.0-2.02.62.0-2.62.1-1.51.51.7-1.91.91.92.2-1.81.60.7-0.8-0.2-0.8-0.30.10.1
Pavlov. Cond. change in total contacts1.51.64.9-1.62.21.5-2.21.6-0.90.91.1-1.41.51.51.8-1.31.00.2-0.3-0.1-0.8-0.50.4-0.1
Pavlov. Cond. index score1.82.36.2-2.02.51.8-2.42.0-1.21.21.4-1.71.81.82.0-1.61.60.4-0.50.1-0.5-0.60.4-0.4
Pavlov. Cond. latency score1.51.95.4-1.82.31.6-2.31.8-1.11.11.2-1.51.61.61.8-1.41.50.2-0.30.3-0.3-0.80.5-0.6
Pavlov. Cond. lever contacts0.91.04.1-1.12.01.1-2.01.3-0.50.50.6-1.11.11.11.4-1.11.00.0-0.10.3-0.3-0.40.2-0.3
Pavlov. Cond. magazine entry number1.31.64.41.6-2.1-1.52.1-1.71.0-1.0-1.21.5-1.4-1.4-1.81.4-1.2-0.40.5-0.00.60.4-0.20.0
Pavlov. Cond. intertrial magazine entries0.91.13.4-1.90.71.1-0.60.9-1.41.41.3-0.80.70.71.2-0.4-0.40.2-0.0-1.1-1.2-1.51.60.1
Pavlov. Cond. lever-magazine prob. diff.1.51.95.3-1.92.31.6-2.31.8-1.11.11.3-1.51.61.61.8-1.41.40.3-0.30.2-0.3-0.70.5-0.5
Pavlov. Cond. response bias1.62.06.8-1.82.61.7-2.61.8-1.01.01.2-1.61.51.51.9-1.51.30.2-0.30.1-0.4-0.60.4-0.3
Pavlov. Cond. lever latency0.20.30.70.7-0.9-0.40.7-0.60.2-0.2-0.30.4-0.5-0.5-0.70.5-0.80.3-0.20.1-0.30.7-0.60.8
Pavlov. Cond. magazine entry latency1.82.13.71.9-1.5-1.91.6-1.41.8-1.8-1.81.6-1.4-1.3-1.61.1-0.2-1.21.11.61.90.0-0.0-1.5
Pavlov. Cond. change in total contacts0.30.41.3-0.50.90.4-0.80.9-0.30.30.4-0.50.60.71.1-1.01.10.1-0.2-0.3-0.1-0.0-0.0-0.3
Pavlov. Cond. index score0.20.21.20.30.2-0.4-0.00.10.5-0.5-0.40.2-0.10.00.1-0.10.7-0.50.50.50.9-0.30.2-1.1
Pavlov. Cond. latency score0.20.31.60.40.1-0.60.0-0.00.6-0.6-0.60.4-0.2-0.1-0.0-0.10.7-0.60.60.71.1-0.30.2-1.3
Pavlov. Cond. lever contacts0.20.20.6-0.80.70.4-0.60.6-0.30.30.4-0.30.40.40.6-0.30.5-0.20.2-0.10.1-0.80.7-0.7
Pavlov. Cond. magazine entry number2.53.15.3-2.11.62.2-1.71.8-2.22.22.2-2.01.81.71.8-1.40.41.6-1.6-1.9-2.30.3-0.31.9
Pavlov. Cond. intertrial magazine entries11.414.821.4-4.33.84.5-3.94.1-4.64.64.5-4.54.13.94.1-3.71.93.7-3.7-3.7-4.31.3-1.33.7
Pavlov. Cond. lever-magazine prob. diff.0.20.21.30.30.0-0.50.1-0.00.5-0.5-0.50.3-0.2-0.1-0.0-0.10.7-0.50.50.51.0-0.30.2-1.1
Pavlov. Cond. response bias0.10.10.6-0.30.20.0-0.10.2-0.00.00.10.00.10.20.1-0.10.5-0.30.2-0.00.6-0.50.4-0.8
Time in closed arm before self-admin1.01.12.80.7-0.8-0.90.9-0.90.8-0.8-0.81.1-0.6-0.5-1.01.2-0.4-1.31.31.61.4-1.00.9-1.7
Time in closed arm after self-admin0.40.42.40.90.0-0.5-0.0-0.10.4-0.4-0.60.10.20.2-0.8-0.01.20.1-0.20.61.51.0-1.1-0.7
Time in open arm before self-admin0.40.41.11.1-0.2-0.8-0.0-0.60.9-0.9-1.00.5-0.7-0.7-0.80.30.0-0.20.10.50.80.6-0.7-0.1
Time in open arm after self-admin0.30.31.50.1-0.5-0.20.6-0.30.3-0.3-0.20.3-0.7-0.70.20.2-1.2-0.10.1-0.1-1.1-0.30.40.8
Bone: periosteal estimation9.219.026.7-4.95.05.0-4.95.2-5.05.04.9-5.05.25.24.2-4.64.74.0-3.9-4.0-2.21.3-1.61.8
Bone: periosteal perimeter4.57.413.5-3.43.73.3-3.53.3-2.92.92.8-3.33.33.22.4-2.93.42.2-2.2-2.1-0.40.4-0.70.2
Bone: post-yield work2.93.95.6-1.92.12.1-2.12.3-2.22.22.1-2.32.42.41.7-2.12.42.1-2.0-2.1-0.81.1-1.21.0
Progressive ratio test 1 active lever presses3.23.38.5-2.92.42.5-2.22.2-2.22.22.2-2.02.12.12.2-1.61.30.6-0.6-0.2-0.8-1.21.1-0.2
Progressive ratio test 1 breakpoint3.84.010.2-3.22.62.7-2.32.3-2.42.42.5-2.12.22.22.6-1.71.20.6-0.6-0.1-1.2-1.51.3-0.0
Progressive ratio test 1 inactive lever presses3.63.99.8-3.12.22.5-2.22.3-2.62.62.2-2.12.52.52.4-1.71.50.5-0.5-0.1-0.9-1.51.3-0.5
Progressive ratio test 2 active lever presses3.43.77.5-2.72.62.7-2.22.3-2.22.22.3-2.22.02.02.2-1.91.21.2-1.2-1.1-1.4-0.40.21.0
Progressive ratio test 2 breakpoint3.94.48.0-2.72.82.8-2.62.5-2.42.42.4-2.52.22.22.4-2.21.51.4-1.5-1.4-1.6-0.0-0.11.2
Progressive ratio test 2 inactive lever presses3.54.09.3-3.02.32.8-2.22.2-2.72.72.5-2.32.22.12.1-1.61.01.2-1.2-1.4-1.6-0.70.60.9
Incentive Sensitization - Responses2.72.84.7-1.72.22.0-2.11.9-1.81.81.7-2.01.61.61.9-1.91.31.5-1.6-1.4-1.40.7-0.81.4
Incentive Sensitization - Breakpoint2.72.84.7-1.62.21.9-2.11.9-1.71.71.6-2.01.71.61.8-2.01.41.6-1.6-1.3-1.20.8-0.91.4
Sum of active levers in priming session hrs 5-61.11.11.81.0-0.9-1.31.0-0.91.4-1.4-1.31.1-1.1-1.1-0.10.7-1.1-1.31.30.90.1-1.01.1-0.9
Progressive ratio0.20.20.90.3-0.2-0.10.50.10.0-0.0-0.1-0.1-0.0-0.1-0.5-0.40.50.6-0.6-0.60.41.0-1.00.5
Food seeking constrained by brief footshock4.55.58.3-1.42.32.1-2.52.7-2.22.22.2-2.62.62.72.4-2.92.52.6-2.6-1.9-2.12.3-2.32.1
Seeking ratio, punishment vs. effort1.31.53.7-1.11.51.3-1.91.5-1.21.21.4-1.41.51.51.8-1.31.00.9-0.9-0.4-1.50.3-0.30.7
Retroperitoneal fat weight2.06.510.6-2.92.73.3-2.92.7-3.23.23.2-3.02.92.82.0-2.11.82.6-2.4-2.2-1.91.0-1.12.0
Reaction time number correct1.11.53.40.5-0.7-0.90.9-1.21.2-1.2-1.31.3-1.5-1.5-1.41.3-0.9-1.31.41.11.8-1.41.4-1.5
Reaction time mean minus median0.30.41.11.0-1.0-0.70.9-0.60.6-0.6-0.60.6-0.7-0.7-0.60.3-0.70.1-0.10.2-0.40.8-0.70.9
Reaction time mean minus median AUC0.91.12.71.1-1.6-1.31.6-1.21.0-1.0-1.21.2-1.1-1.2-1.41.1-0.9-0.80.80.70.8-0.20.2-0.5
Reaction time num false alarms2.22.95.7-2.42.41.9-2.22.2-1.81.82.0-1.92.12.12.1-1.81.90.6-0.7-0.7-0.4-0.70.5-0.3
Reaction time num false alarms AUC2.53.56.6-2.52.62.1-2.42.4-2.02.02.2-2.12.22.22.1-2.02.01.0-1.1-1.1-0.6-0.40.20.0
Reaction time trials correct on left1.11.53.40.5-0.7-0.90.9-1.21.2-1.2-1.31.3-1.5-1.5-1.41.3-0.9-1.31.41.11.8-1.41.4-1.5
Reaction time trials on left1.01.43.30.4-0.7-0.80.9-1.21.1-1.1-1.21.2-1.4-1.4-1.41.3-0.9-1.31.31.01.8-1.31.3-1.4
Reaction time mean0.50.72.11.5-1.4-1.31.3-0.80.9-0.9-0.90.9-0.8-0.7-1.00.5-0.3-0.20.30.50.40.7-0.6-0.0
Reaction time mean AUC0.81.13.21.8-1.6-1.61.6-1.01.2-1.2-1.11.2-1.0-0.9-1.00.6-0.4-0.30.40.70.40.8-0.7-0.1
Median of all reaction times0.40.61.81.4-1.3-1.21.2-0.80.8-0.8-0.70.9-0.7-0.6-0.90.5-0.1-0.20.30.50.60.6-0.5-0.3
Reaction time omissions0.20.31.1-0.0-0.50.20.40.1-0.50.50.5-0.20.10.2-0.4-0.1-0.10.8-0.8-0.8-0.40.9-0.81.1
Reaction time false alarm rate3.04.16.6-2.12.52.1-2.52.6-2.12.12.3-2.32.52.62.5-2.42.21.4-1.5-1.3-1.40.5-0.60.7
Reaction time premature initiation rate0.50.62.0-1.40.71.0-0.70.6-0.90.90.8-0.70.80.60.8-0.2-0.4-0.10.1-0.7-1.0-1.21.2-0.0
Reaction time premature initiations0.30.53.0-1.10.40.5-0.3-0.0-0.30.30.1-0.10.0-0.10.10.4-0.8-0.70.7-0.2-0.0-1.71.7-0.7
Std. dev. reaction times0.40.62.41.2-1.1-0.81.0-0.50.4-0.4-0.40.4-0.5-0.4-0.80.1-0.20.5-0.6-0.4-0.31.6-1.41.1
Reaction time trials completed1.01.43.30.4-0.7-0.80.9-1.21.1-1.1-1.21.2-1.4-1.4-1.41.3-0.9-1.31.31.01.8-1.31.3-1.4
Reaction time trials AUC0.91.33.10.4-0.7-0.80.9-1.21.0-1.0-1.21.2-1.4-1.4-1.41.2-0.8-1.21.20.91.8-1.21.2-1.3
Run reversals in cocaine runway, females0.50.52.00.8-0.8-0.30.3-0.90.4-0.4-0.80.5-0.7-0.7-0.90.9-1.4-0.10.1-0.0-0.50.5-0.31.0
Run reversals in cocaine runway, males0.10.10.20.3-0.3-0.40.2-0.40.4-0.4-0.40.3-0.4-0.5-0.50.4-0.3-0.30.3-0.20.4-0.10.1-0.2
Latency to leave start box in cocaine runway0.30.40.70.7-0.6-0.80.5-0.60.7-0.7-0.50.7-0.5-0.4-0.60.5-0.1-0.50.50.80.7-0.20.2-0.8
Latency to leave start box in cocaine runway, F1.11.23.40.7-0.8-1.20.7-0.91.1-1.1-1.01.1-0.8-0.7-1.11.0-0.2-1.31.31.61.5-1.01.0-1.8
Latency to leave start box in cocaine runway, M0.30.31.60.6-0.1-0.00.00.1-0.10.10.1-0.20.10.20.3-0.40.10.8-0.8-0.8-0.71.3-1.21.1
Std. dev. time between licks in bursts0.10.10.4-0.1-0.50.00.4-0.2-0.20.20.20.1-0.1-0.1-0.20.2-0.60.0-0.00.3-0.6-0.10.20.4
Total sessions with >9 infusions1.51.68.8-1.40.50.5-0.2-0.1-0.10.10.30.4-0.3-0.30.20.8-0.9-1.81.81.60.6-3.02.9-1.8
Short access day 1 total inactive lever presses1.01.12.6-1.61.31.3-1.51.1-1.41.41.2-1.11.31.30.7-0.60.90.2-0.20.00.1-0.70.6-0.5
Short access day 10 total inactive lever presses0.70.81.7-0.90.30.9-0.50.8-1.21.20.9-1.01.21.10.8-0.70.31.0-1.0-1.3-1.30.2-0.20.8
Short access day 1 total infusions1.61.89.1-2.00.91.0-0.80.5-0.80.80.9-0.20.50.50.90.3-0.5-1.41.41.40.1-3.02.9-1.7
Short access day 10 total infusions4.75.211.8-3.42.33.1-2.12.5-3.23.23.0-2.52.82.72.5-1.71.21.3-1.3-1.2-1.9-0.80.70.8
Short access total infusions2.22.56.8-2.61.72.0-1.41.7-1.91.91.9-1.41.91.92.0-1.00.7-0.10.10.3-0.9-1.81.7-0.7
Short access day 1 locomotion2.42.69.3-3.01.52.1-1.51.3-2.02.02.0-1.21.31.21.5-0.4-0.4-0.50.5-0.3-1.2-2.52.4-0.3
Short access day 10 total locomotion8.08.916.1-4.03.64.0-3.53.5-3.63.63.8-3.43.33.33.4-2.71.61.8-1.9-2.2-2.9-0.20.11.8
Short access total locomotion3.63.811.1-3.32.22.7-2.12.1-2.52.52.5-1.92.22.02.2-1.10.50.1-0.2-0.4-1.6-1.81.70.1
One hour access (0.3 mA shock)0.81.01.9-1.11.01.1-0.91.2-1.21.21.1-1.11.31.41.3-1.21.10.8-0.8-0.4-0.70.2-0.20.3
Compulsive drug intake0.80.93.31.1-0.5-1.10.5-0.91.1-1.1-1.50.9-0.7-0.7-1.10.70.3-0.50.50.71.80.1-0.1-1.2
One hour access (shock baseline)1.21.43.0-1.51.11.5-1.01.4-1.51.51.7-1.31.31.31.5-1.10.50.8-0.8-0.7-1.5-0.00.01.0
Social response proportion0.30.30.50.5-0.4-0.50.4-0.60.7-0.7-0.50.6-0.7-0.6-0.50.6-0.6-0.60.70.30.5-0.50.6-0.5
Social responses0.20.21.0-0.40.40.1-0.40.20.0-0.00.2-0.10.40.50.4-0.00.3-0.40.50.50.3-0.90.9-1.0
Social time0.10.20.60.80.0-0.3-0.1-0.10.5-0.5-0.70.1-0.3-0.30.4-0.3-0.20.2-0.10.0-0.30.6-0.50.6
Soleus weight0.20.52.8-0.80.70.2-0.60.10.2-0.2-0.10.0-0.0-0.10.50.2-0.2-0.80.90.80.4-1.71.5-1.3
Bone: stiffness1.32.04.5-2.11.41.6-1.21.6-1.91.91.8-1.41.71.71.0-1.11.80.9-0.8-1.50.4-0.50.4-0.6
Tibialis anterior weight0.20.65.3-0.70.00.6-0.10.1-0.60.60.6-0.50.40.10.70.2-1.50.2-0.3-0.4-2.3-0.30.41.4
Time to tail flick, vehicle, before self-admin0.40.41.60.80.0-0.5-0.1-0.10.4-0.4-0.50.0-0.2-0.2-0.7-0.30.90.6-0.6-0.91.11.2-1.30.1
Time to tail flick, vehicle, after self-admin0.30.41.7-0.80.50.7-0.30.5-0.60.60.7-0.60.20.20.4-0.60.00.7-0.7-1.3-0.60.1-0.10.8
Time to tail flick, test, before self-admin0.70.72.51.5-0.7-0.80.5-0.60.9-0.9-1.10.5-0.8-0.8-0.50.1-0.30.4-0.4-0.7-0.21.6-1.51.0
Time to tail flick, test, after self-admin0.30.30.50.3-0.2-0.5-0.0-0.60.5-0.5-0.50.5-0.7-0.7-0.50.6-0.7-0.60.60.10.4-0.60.6-0.4
Delta time to tail flick, vehicle, before/after SA1.81.83.9-1.51.01.7-0.91.3-1.71.71.6-1.41.31.21.4-1.10.21.3-1.3-1.5-2.00.4-0.31.6
Delta time to tail flick, test, before/after SA0.10.10.6-0.40.0-0.10.1-0.1-0.00.00.00.1-0.1-0.1-0.20.10.0-0.30.40.10.5-0.80.7-0.7
Tibia length0.41.24.9-1.21.00.5-0.9-0.10.1-0.1-0.10.2-0.3-0.3-0.90.70.3-1.31.20.92.2-2.01.8-2.2
Ambulatory time before self-admin0.40.41.60.7-0.1-0.70.2-0.20.8-0.8-0.80.5-0.4-0.4-0.4-0.00.6-0.30.31.21.30.2-0.3-0.8
Ambulatory time after self-admin0.10.20.80.10.0-0.2-0.00.20.2-0.2-0.20.10.10.20.4-0.30.7-0.30.30.80.6-0.30.2-0.9
Bone: tissue strength1.21.23.30.5-0.7-0.90.7-0.90.8-0.8-0.91.1-1.0-0.9-1.31.1-0.4-1.21.31.31.8-1.21.1-1.6
Total heroin consumption0.20.30.9-0.30.80.1-0.60.60.0-0.00.2-0.30.40.40.9-0.70.9-0.20.20.60.4-0.30.2-0.7
Bone: trabecular number1.52.45.2-2.12.32.2-2.21.8-1.71.71.5-1.81.61.51.0-1.51.71.2-1.2-1.30.10.1-0.30.3
Bone: trabecular spacing0.40.51.51.2-1.0-1.20.9-0.70.9-0.9-0.60.8-0.6-0.6-0.20.4-0.6-0.30.40.9-0.30.3-0.20.1
Bone: trabecular thickness1.61.94.6-2.12.12.1-2.11.5-1.61.61.4-1.71.31.20.7-1.10.81.0-1.1-1.6-0.50.0-0.20.9
Bone: trabecular tissue density1.31.83.9-0.2-1.1-0.61.3-1.40.6-0.6-0.51.3-1.3-1.3-2.01.8-1.2-1.41.40.71.8-2.02.0-1.7
Water consumed over 24 hours0.20.20.8-0.90.60.8-0.60.3-0.70.70.5-0.40.50.40.00.1-0.0-0.10.10.00.2-0.60.5-0.2
Number of responses in last shaping day0.40.41.2-1.10.80.8-0.70.6-0.40.40.5-0.30.40.50.8-0.20.0-0.40.40.5-0.2-1.11.0-0.5