Hub : Genes

Ddx42

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Ddx42 0.02 0.01 1.6e-03 0.02 0.02 0.02 0.02 3.2e-04 5.2e-04 6.3e-04 3.9e-04
2 BLA mRNA stability Ddx42 0.09 0.05 1.7e-04 0.09 0.04 0.05 0.06 3.0e-05 3.7e-03 1.7e-03 7.4e-04
3 Adipose gene expression Ddx42 0.12 0.05 7.5e-10 0.03 0.05 0.05 0.06 1.7e-04 3.5e-06 4.9e-06 7.2e-07
4 PL mRNA stability Ddx42 0.03 0.02 1.0e-03 0.03 0.02 0.01 0.02 4.1e-04 5.7e-03 9.4e-03 5.0e-03
5 RMTg mRNA stability Ddx42 0.23 0.1 1.9e-05 0.11 0.16 0.13 0.14 6.6e-04 6.5e-05 3.4e-04 1.9e-04
6 pVTA mRNA stability Ddx42 0.11 0.06 2.3e-04 0.03 0.04 0.05 0.04 4.2e-03 6.1e-04 1.0e-04 7.8e-04
7 NAcc mRNA stability Ddx42 0.02 0.02 6.5e-03 -0 0.01 0 0 7.1e-01 3.6e-02 2.4e-01 3.5e-01
8 Brain mRNA stability Ddx42 0.07 0.03 2.6e-05 0.01 0.05 0.04 0.04 1.4e-02 2.6e-05 1.4e-04 2.1e-04
9 Liver gene expression Ddx42 0.07 0.04 1.8e-04 0.04 0.04 0.04 0.03 4.4e-05 8.7e-05 7.2e-05 9.9e-05
10 Adipose mRNA stability Ddx42 0.13 0.05 5.4e-13 0.06 0.11 0.12 0.12 3.9e-07 1.3e-12 1.2e-13 4.8e-13
11 LHb mRNA stability Ddx42 0.55 0.12 8.3e-07 0.16 0.22 0.2 0.23 1.2e-04 6.8e-06 1.7e-05 4.2e-06
12 Liver mRNA stability Ddx42 0.05 0.03 1.4e-03 0.03 0.02 0.02 0.02 9.9e-05 6.4e-03 4.6e-03 1.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.22.27.81.6-0.7-2.8-0.90.1-0.9-0.5-1.42.70.7-1.61.3
Area under the delay curve0.20.40.70.5-0.5-0.8-0.4-0.9-0.40.8-0.80.80.2-0.4-0.3
BMI with tail1.03.57.71.9-2.2-0.6-2.40.2-1.72.82.5-1.2-1.71.8-1.6
BMI without tail1.15.711.73.4-3.2-2.0-3.20.5-2.93.22.5-0.3-1.81.9-0.9
Body weight1.88.020.94.6-3.7-3.1-4.01.5-2.54.32.30.3-1.61.1-0.0
Weight adjusted by age0.20.61.3-1.10.80.71.0-1.11.00.3-0.6-0.50.4-0.0-0.9
Bone surface2.75.318.43.6-2.0-4.3-2.31.6-0.71.1-0.93.00.4-1.32.6
Bone volume2.24.416.13.2-1.8-4.0-2.11.1-1.01.0-1.02.90.4-1.22.0
Breakpoint value in progressive ratio session0.30.51.4-0.4-0.30.2-0.71.2-0.7-0.60.7-0.3-1.11.10.1
Number of licking bursts0.00.10.2-0.3-0.1-0.10.0-0.10.40.2-0.40.00.0-0.50.0
Context. condit. distance diff. score0.40.52.8-0.4-0.41.20.1-0.2-0.20.40.8-1.7-0.40.7-0.6
Locomotion velocity, session 11.01.23.71.7-1.0-1.9-0.50.4-0.50.0-0.61.30.7-0.91.6
Locomotion distance, session 10.40.61.10.90.1-0.70.3-0.8-0.4-0.0-1.11.00.8-1.00.9
Locomotion velocity, session 20.40.42.50.4-0.1-0.6-0.31.6-0.5-0.80.40.1-0.50.50.8
Locomotion distance, session 20.20.31.20.00.30.40.5-0.0-0.5-0.5-0.5-0.40.3-0.51.1
Locomotion velocity, session 30.50.61.2-0.70.7-0.10.7-0.70.1-0.9-0.90.51.1-1.10.6
Locomotion distance, session 30.30.30.7-0.30.6-0.40.3-0.00.4-0.3-0.80.60.7-0.80.8
Stereotopy head waving bouts, day 30.50.61.6-0.50.3-0.60.5-0.9-0.0-1.0-1.11.21.0-1.00.3
Stereotopy head waving duration, day 30.30.31.3-0.80.10.10.4-1.1-0.3-0.3-0.80.40.5-0.4-0.7
Locomotion velocity, session 70.40.41.0-0.91.00.20.7-0.40.3-1.0-0.40.20.7-0.50.7
Locomotion distance, session 70.20.31.1-0.60.70.50.4-0.3-0.10.10.1-0.6-0.31.1-0.7
Stereotopy head waving bouts, day 70.80.92.2-0.80.70.00.9-0.50.4-1.5-1.10.61.1-1.31.1
Stereotopy head waving duration, day 71.31.54.4-1.61.30.91.4-0.50.5-2.1-1.30.11.1-1.71.0
Locomotion velocity, session 80.60.82.80.5-1.10.5-0.81.0-0.21.11.2-1.7-0.30.00.7
Locomotion distance, session 80.50.73.3-0.1-0.41.2-0.10.3-1.20.30.7-1.8-0.80.6-0.3
Degree of sensitization distance0.60.71.90.6-0.40.5-0.4-0.1-0.51.20.7-1.1-0.81.4-1.0
Degree of sensitization stereotypy1.01.13.4-1.00.90.71.2-0.30.6-1.8-0.9-0.01.1-1.21.4
Conditioned locomotion1.11.33.70.2-0.50.4-1.00.7-1.60.81.1-0.8-1.91.4-1.7
Cocaine response after cond. corrected0.81.24.8-0.60.6-0.71.0-1.12.20.4-1.51.11.2-1.00.2
Cocaine response after cond. not corrected1.62.47.2-0.80.9-1.21.4-0.72.7-0.7-2.01.81.9-1.71.5
Cocaine response before conditioning0.70.93.2-0.30.3-0.60.30.50.2-1.6-0.81.01.0-1.01.8
Saline control response3.34.510.00.7-1.90.2-2.02.1-2.31.13.0-1.7-3.23.1-1.9
Bone: connectivity density1.32.17.91.9-1.1-2.8-1.20.7-1.1-0.2-1.02.20.3-1.01.6
Bone: cortical apparent density2.13.37.9-2.12.51.72.1-2.8-0.1-2.1-1.90.21.6-1.6-0.7
Bone: cortical area1.32.07.71.7-0.5-2.8-0.7-0.4-0.10.1-1.22.71.0-1.41.1
Bone: cortical porosity4.24.617.82.5-1.7-4.2-1.83.11.10.40.52.9-0.00.02.3
Bone: cortical porosity3.13.413.72.4-1.3-3.7-1.72.10.80.70.12.60.3-0.52.1
Bone: cortical thickness5.59.116.1-2.13.5-0.23.1-4.01.8-3.3-3.83.13.7-3.70.8
Bone: cortical thickness3.13.89.1-1.72.80.02.2-2.00.9-3.0-2.21.82.0-1.81.0
Bone: cortical tissue density1.93.17.0-2.12.41.72.0-2.6-0.2-2.1-1.80.11.5-1.5-0.7
Condit. Reinf. active minus inactive responses1.82.13.71.5-1.9-1.5-1.81.9-1.40.81.30.5-1.61.6-0.1
Condit. Reinf. active-inactive response ratio0.70.82.00.8-1.1-0.9-1.11.4-0.70.30.90.4-1.01.00.2
Condit. Reinf. active responses2.43.15.31.9-2.3-1.5-2.32.0-2.21.31.60.0-2.11.9-0.5
Condit. Reinf. inactive responses0.81.13.21.4-1.3-0.7-1.40.5-1.81.20.4-0.3-1.00.7-0.3
Incentive salience index mean1.41.84.21.7-1.5-1.7-1.72.1-1.30.30.91.0-1.20.80.7
Condit. Reinf. lever presses0.40.72.21.0-0.1-0.6-0.81.5-1.0-0.70.30.6-0.3-0.31.3
Condit. Reinf. active minus inactive responses2.43.710.32.7-2.5-3.2-2.51.9-2.11.10.01.6-1.10.41.2
Condit. Reinf. active-inactive response ratio1.52.37.81.9-2.0-2.8-1.71.9-0.90.4-0.01.6-0.70.01.4
Condit. Reinf. active responses3.44.99.22.9-2.9-2.8-3.02.3-2.81.61.10.9-2.01.50.4
Condit. Reinf. inactive responses1.82.77.51.4-1.5-0.6-2.01.0-2.71.21.5-0.5-2.12.3-1.3
Condit. Reinf. lever presses1.11.63.21.7-1.4-1.5-1.61.8-1.60.30.90.6-1.10.70.7
Condit. Reinf. lever reinforcers received3.14.38.32.8-2.8-2.9-2.82.1-2.51.40.91.1-1.81.30.4
Conditioned reinforcement - actives0.20.71.71.2-1.1-0.1-0.60.4-0.91.31.0-0.7-0.60.6-0.4
Conditioned reinforcement - inactives0.30.82.41.6-1.4-1.3-0.90.7-0.40.80.80.4-0.10.10.7
Conditioned locomotion1.52.25.72.4-2.3-1.6-1.61.5-1.31.61.40.4-0.80.70.4
Patch foraging indifference point 0 sec1.74.710.02.6-3.1-2.0-2.91.3-3.22.01.4-0.6-2.41.6-0.9
Patch foraging indifference point AUC0.30.81.71.2-1.1-0.1-1.10.5-1.31.20.9-0.6-0.70.1-0.4
Delay disc. indifference point, 0s delay0.30.30.8-0.80.60.60.3-0.9-0.1-0.0-0.8-0.1-0.3-0.3-0.9
Delay disc. indifference point, 16s delay0.50.71.90.7-1.0-1.2-0.8-0.5-0.51.4-0.20.8-0.40.3-1.0
Delay disc. indifference point, 2s delay0.80.92.11.0-0.7-1.1-0.8-0.7-0.90.9-1.41.10.6-1.30.8
Delay disc. indifference point, 24s delay0.81.34.01.7-1.5-1.2-1.4-0.2-1.52.00.40.2-0.50.1-0.6
Delay disc. indifference point, 4s delay1.01.12.4-0.80.8-0.51.0-1.01.4-0.6-1.51.51.3-1.00.6
Delay disc. indifference point, 8s delay0.30.41.40.2-0.0-0.7-0.1-1.1-0.40.0-1.11.20.5-0.7-0.2
Indifference point function ln k0.20.61.6-0.80.6-0.70.4-1.0-0.0-1.1-1.30.90.5-0.5-0.4
Indifference point function log k0.20.61.6-0.80.6-0.70.4-1.0-0.0-1.1-1.30.90.5-0.5-0.4
Patch foraging total patch changes 0 sec1.64.710.22.7-3.2-2.2-2.91.3-3.02.11.3-0.4-2.31.6-0.8
Patch foraging total patch changes 12 sec4.05.410.92.7-2.9-0.5-2.82.2-3.32.42.2-1.6-2.82.0-0.7
Patch foraging total patch changes 18 sec1.22.85.91.9-2.4-1.4-2.11.6-1.71.61.7-0.6-2.01.7-0.5
Patch foraging total patch changes 24 sec0.82.86.42.5-2.5-2.0-2.30.9-2.51.40.60.7-1.10.40.3
Patch foraging total patch changes 6 sec1.22.14.01.9-2.0-1.7-2.01.2-1.91.31.00.2-1.50.7-0.2
Patch foraging time to switch 0 sec0.10.51.9-1.01.00.50.90.41.4-1.0-0.00.50.30.30.3
Patch foraging water rate 0 sec0.51.94.82.2-2.0-1.7-2.00.5-1.91.50.70.1-0.80.5-0.1
Patch foraging water rate 12 sec0.62.55.3-0.71.2-0.81.3-2.01.7-0.9-2.11.72.3-1.91.3
Patch foraging water rate 18 sec0.61.33.20.20.5-1.10.3-0.90.1-0.9-1.81.61.4-1.51.4
Patch foraging water rate 24 sec0.30.41.60.10.3-0.10.4-0.60.50.0-1.00.21.1-0.61.3
Patch foraging water rate 6 sec0.60.92.80.4-0.2-1.50.0-0.9-0.2-0.5-1.41.71.0-1.10.8
Seeking ratio, delayed vs. immediate footshock0.30.41.10.2-0.10.7-0.20.1-0.30.41.0-1.0-0.70.7-0.7
Distance traveled before self-admin0.51.13.0-1.30.9-0.51.0-0.81.7-0.5-1.51.31.1-0.90.4
Distance traveled after self-admin0.10.20.5-0.60.70.40.3-0.00.70.0-0.5-0.20.1-0.30.6
Extensor digitorum longus weight1.66.216.9-2.50.94.10.8-1.60.91.62.5-3.8-1.42.3-4.1
Bone: elastic displacement2.22.85.8-1.01.9-0.01.7-1.61.5-1.8-1.81.62.4-2.11.2
Bone: elastic work1.11.54.10.61.0-1.20.4-0.50.6-1.0-1.02.01.7-1.71.7
Bone: endosteal estimation6.916.933.75.8-5.6-4.9-5.35.5-2.34.13.10.5-3.43.01.6
Bone: endosteal perimeter7.117.437.66.1-5.8-4.9-5.64.8-2.25.22.90.8-3.12.31.4
Epididymis fat weight0.21.02.71.2-1.4-0.8-1.20.3-0.81.61.0-0.5-0.71.1-0.8
Delta time in closed arm before/after self-admin0.80.71.5-0.20.7-0.40.7-0.10.9-0.7-0.91.21.2-1.11.1
Delta time in open arm before/after self-admin1.72.06.2-0.3-0.61.4-0.6-0.1-1.70.81.2-2.5-1.71.6-2.2
Diff in mean of infusions in LGA sessions0.61.13.2-1.81.01.81.2-0.70.0-1.40.0-1.0-0.10.3-0.6
Delay discount exponential model param0.30.40.9-0.70.60.90.50.70.5-0.90.7-0.7-0.20.40.1
Extinction: sum of active levers before priming0.81.23.3-0.4-0.50.9-0.60.1-1.60.50.9-1.8-1.41.4-1.4
Active lever presses in extinction session 61.31.32.60.9-1.6-1.2-1.51.3-0.80.81.2-0.1-1.41.5-0.4
Bone: final force1.32.15.81.2-0.1-2.3-0.1-0.70.5-0.1-1.82.41.5-2.01.7
Bone: final moment1.52.47.01.2-0.1-2.5-0.1-0.60.6-0.3-1.92.61.6-2.01.9
Food consumed during 24 hour testing period1.63.25.72.4-2.2-0.7-2.41.4-1.92.32.1-1.3-1.31.6-0.1
Glucose0.91.43.6-1.51.50.91.6-1.41.9-0.3-1.0-0.21.2-0.9-0.3
Heart weight0.81.33.90.20.6-0.40.4-2.01.00.7-1.61.01.8-1.60.2
Delay discount hyperbolic model param0.30.40.8-0.70.60.90.50.70.4-0.90.8-0.8-0.30.5-0.1
Intermittent access intake day 1-15 change0.10.51.4-0.30.00.60.20.81.00.41.1-1.2-0.50.8-0.2
Intermittent access intake escalation0.10.61.70.2-0.50.2-0.31.00.70.91.3-1.2-0.81.0-0.2
Intermittent access intake escalation 20.50.82.10.4-0.50.1-0.51.30.70.91.5-1.0-0.91.1-0.1
Intermitt. access day 1 inactive lever presses0.22.75.02.1-2.2-2.0-2.22.2-1.50.71.60.3-1.61.40.2
Intermitt. access day 15 inactive lever presses0.42.34.51.4-2.1-2.0-1.31.7-0.80.21.70.7-1.82.0-1.0
Intermitt. access escalation Index0.61.94.5-2.11.51.31.7-1.62.1-0.7-1.5-0.11.1-0.8-0.2
Intermittent access day 1 total infusions0.20.71.81.4-1.2-0.9-0.90.3-1.20.60.00.10.1-0.31.0
Intermittent access day 15 total infusions0.61.54.31.7-1.8-0.5-1.40.8-0.72.11.4-1.1-0.60.70.0
Intermittent access terminal intake (last 3 days)1.32.35.42.3-2.2-0.8-1.71.4-1.12.31.7-1.1-1.00.90.2
Intermittent access total infusions1.72.05.52.3-2.1-0.7-1.61.0-1.72.01.1-1.0-0.50.20.7
Intermittent access day 1 locomotion1.42.67.82.8-2.2-2.1-2.01.4-1.51.20.90.9-0.1-0.21.7
Intermittent access day 15 total locomotion1.14.211.13.3-3.0-1.2-2.62.0-2.22.32.0-0.9-0.90.31.4
Intermittent access total locomotion4.25.115.43.9-3.2-2.1-2.72.2-2.72.01.8-0.1-0.80.31.8
Intermittent access standard deviation0.10.81.81.4-1.0-0.3-0.91.2-0.80.51.2-0.8-0.1-0.01.1
Left kidney weight0.32.25.90.01.1-0.80.9-1.70.5-0.8-2.31.71.9-2.41.5
Right kidney weight0.43.010.10.80.6-1.20.5-1.60.5-0.3-2.41.92.4-3.22.1
Cocaine induced anxiety0.71.93.6-0.41.0-0.71.0-1.01.3-1.3-1.61.91.9-1.81.7
Post-drug Anxiety1.92.25.0-0.41.1-0.51.0-1.21.5-1.1-1.61.72.2-2.11.9
Baseline Anxiety0.00.00.1-0.20.10.30.1-0.40.20.00.1-0.10.3-0.2-0.1
Tail length1.05.415.94.0-2.7-3.5-2.72.3-2.41.51.11.7-0.90.31.9
Length with tail1.04.315.43.9-2.3-2.7-2.61.8-1.42.70.60.9-0.3-0.71.9
Length without tail0.10.52.21.2-0.2-0.4-0.50.20.41.5-0.1-0.00.6-1.00.8
Times rat made contact with spout0.50.62.51.6-0.8-0.7-0.90.9-0.30.60.50.30.1-0.21.0
Lifetime Intake1.82.35.72.4-2.4-1.0-1.81.0-1.91.91.2-0.8-0.80.50.4
Liver weight, left2.03.49.33.1-1.8-2.4-2.22.4-1.20.90.31.4-0.1-0.82.6
Liver weight, right2.13.76.8-0.21.8-0.91.6-1.71.0-2.0-2.62.52.3-2.62.0
Locomotor activity0.40.61.60.9-1.2-0.2-0.60.8-1.3-0.00.7-1.0-0.50.40.8
Locomotor testing distance0.51.33.11.2-1.8-0.6-1.01.4-1.20.21.4-0.7-1.11.40.3
Locomotor testing rearing0.72.77.00.9-1.70.1-1.02.6-0.8-0.12.6-1.5-2.02.60.3
Locomotion in novel chamber1.82.57.10.31.2-0.71.2-0.22.2-0.3-1.41.82.2-2.12.7
Locomotion in novel chamber post-restriction0.41.13.81.2-1.7-1.5-1.2-0.0-0.41.9-0.60.60.0-0.80.6
Fecal boli incidents, locomotor time 10.20.42.1-0.6-0.30.0-0.00.10.61.00.3-0.4-0.90.7-1.5
Change in fecal boli incidents, locomotor task0.20.20.60.40.50.10.2-0.8-0.00.5-0.20.20.3-0.3-0.8
Time >=10cm from walls, locomotor time 11.82.24.4-1.92.11.61.8-1.22.0-1.1-1.4-0.31.5-0.90.7
Bouts of movement, locomotor time 10.10.10.3-0.40.60.20.1-0.5-0.1-0.60.10.2-0.00.2-0.6
Total resting periods, locomotor time 10.10.10.4-0.40.70.10.3-0.60.1-0.5-0.10.40.2-0.1-0.5
Rest time, locomotor task time 10.10.20.8-0.50.1-0.20.20.00.3-0.4-0.20.5-0.50.3-0.9
Distance moved, locomotor task time 10.10.41.61.1-0.2-0.4-0.40.3-0.40.50.40.20.8-0.31.3
Vertical activity count, locomotor time 10.10.51.70.90.0-0.7-0.20.10.10.3-0.30.91.0-0.51.3
Time >=10cm from walls, locomotor time 20.30.92.6-0.60.6-0.31.00.51.6-1.1-0.50.71.1-0.61.6
Bouts of movement, locomotor time 20.20.52.6-0.90.80.40.1-0.50.3-0.20.30.0-0.61.1-1.6
Total resting periods, locomotor time 20.20.72.7-1.21.20.50.3-0.70.5-0.40.10.1-0.41.0-1.6
Rest time, locomotor task time 21.32.26.9-2.61.81.51.0-1.91.4-0.6-1.2-0.3-0.0-0.0-2.2
Distance moved, locomotor task time 20.81.06.01.2-0.3-0.7-0.21.4-0.2-0.70.70.70.8-0.62.4
Vertical activity count, locomotor time 20.71.74.81.9-1.3-1.6-1.12.2-1.3-0.21.40.7-0.60.71.4
Light reinforcement 10.41.98.70.3-1.1-0.3-1.6-0.6-2.90.40.3-0.5-1.80.9-2.3
Light reinforcement 20.51.24.40.6-0.9-1.1-1.1-0.5-2.10.3-0.20.5-1.20.4-2.1
Bone: marrow area6.616.232.95.7-5.5-4.8-5.25.4-2.24.03.00.6-3.22.91.7
Bone: maximum diameter2.14.213.83.2-2.7-3.7-2.41.4-0.62.1-0.12.3-0.5-0.11.0
Bone: maximum force1.22.37.52.2-0.7-2.7-0.8-0.7-0.01.1-1.52.31.2-1.41.5
Bone: maximum moment1.32.58.22.2-0.7-2.9-0.7-0.60.00.8-1.52.51.3-1.51.6
Mean time between licks in bursts0.10.43.00.5-0.7-0.2-0.2-0.60.71.70.0-0.10.3-0.3-0.5
Mean num. licks in bursts0.10.31.21.1-0.4-0.3-0.70.4-0.80.50.8-0.0-0.20.7-0.1
Cd content in liver2.02.28.6-2.21.92.91.5-0.70.9-0.60.5-1.90.00.1-1.2
Co content in liver0.91.15.1-1.60.72.30.9-0.30.4-0.40.5-1.70.0-0.4-0.7
Cu content in liver0.30.40.90.4-0.5-0.5-0.90.9-0.80.30.70.4-0.90.6-0.2
Fe content in liver0.20.30.8-0.40.90.40.40.7-0.0-0.9-0.30.10.1-0.20.6
K content in liver0.20.21.10.4-0.40.1-0.60.4-1.10.4-0.3-0.3-0.5-0.30.0
Mg content in liver0.60.61.9-0.90.51.40.1-0.1-1.4-0.7-0.1-1.0-0.7-0.2-0.9
Mn content in liver0.80.92.9-0.40.4-0.10.4-0.6-1.2-1.4-1.70.60.6-1.41.1
Na content in liver0.50.62.50.1-0.70.2-1.01.1-1.60.00.5-0.7-1.20.3-0.2
Rb content in liver2.53.06.8-2.32.62.02.1-1.50.9-2.1-1.8-0.01.3-1.70.3
Se content in liver0.81.02.5-1.21.11.50.6-1.6-0.5-0.1-1.0-0.80.2-0.7-1.3
Sr content in liver0.40.41.20.7-0.9-1.1-0.90.3-0.20.60.20.60.0-0.40.3
Zn content in liver0.40.51.0-0.71.00.20.7-0.90.5-0.4-1.00.50.7-0.80.0
Bone: minimum diameter6.111.828.95.4-4.6-4.8-4.63.3-2.24.12.01.5-1.81.31.4
Time in familiar zone, hab. session 11.41.62.90.6-1.10.6-1.01.0-0.51.71.6-1.7-1.61.6-1.1
Time in novel zone, hab. session 11.51.63.4-1.11.3-0.61.3-1.21.0-1.8-1.41.81.5-1.20.5
Total zone transitions, hab. session 10.20.31.80.8-0.3-0.0-0.0-0.3-0.60.4-0.0-0.50.5-0.61.3
Total locomotion distance, hab. session 11.01.46.61.7-0.5-1.6-0.4-0.0-0.9-0.2-0.61.20.9-0.92.6
Locomotion velocity, hab. session 11.11.56.92.0-0.9-1.5-0.60.2-1.10.2-0.40.80.7-0.82.6
Time in familiar zone, hab. session 21.51.73.80.8-1.40.6-1.01.6-0.71.42.0-1.8-1.51.4-0.8
Time in novel zone, hab. session 22.22.45.8-0.71.2-1.11.2-1.80.9-1.5-2.42.41.8-1.51.0
Total zone transitions, hab. session 20.30.31.80.5-0.50.7-0.10.1-1.00.30.4-1.3-0.2-0.20.2
Total locomotion distance, hab. session 20.60.74.31.3-1.1-0.1-0.60.0-2.10.40.4-0.6-0.40.10.1
Locomotion velocity, hab. session 20.50.63.91.4-0.9-0.1-0.5-0.2-2.00.50.2-0.6-0.2-0.10.2
Novel to familiar place preference ratio0.20.21.00.4-0.1-0.9-0.5-0.1-0.10.5-0.21.00.3-0.20.1
Novelty place preference0.10.10.80.10.1-0.7-0.3-0.10.10.1-0.30.90.3-0.30.0
Time in novel zone, NPP test0.20.21.10.10.2-0.7-0.1-0.20.2-0.1-0.41.10.5-0.40.3
Total zone transitions, NPP test0.40.61.70.8-0.30.10.2-0.9-1.30.1-0.8-0.50.7-1.01.0
Total locomotion distance, NPP test0.81.14.31.8-0.9-1.1-0.3-0.0-1.5-0.1-0.50.30.6-0.62.1
Locomotion velocity, NPP test0.50.73.01.6-1.0-0.7-0.5-0.5-1.70.5-0.2-0.20.2-0.21.0
Intraocular pressure0.81.33.30.9-1.6-0.9-0.9-0.3-0.41.81.1-0.2-1.01.8-1.5
Delta distance traveled before/after self-admin0.30.31.2-0.10.31.1-0.30.3-0.8-0.40.6-1.1-0.60.30.2
Delta ambulatory time before/after self-admin0.20.30.90.30.10.7-0.40.4-0.90.20.6-0.9-0.70.5-0.1
Parametrial fat weight0.61.44.01.10.0-1.9-0.4-0.10.50.1-1.32.01.0-1.91.1
Pavlov. Cond. lever latency1.01.33.3-1.80.71.71.2-1.41.10.3-0.2-1.2-0.20.4-1.7
Pavlov. Cond. magazine entry latency2.12.75.92.4-1.9-2.3-2.22.1-2.10.40.81.2-0.90.01.0
Pavlov. Cond. change in total contacts1.71.84.41.6-1.2-1.8-1.72.1-1.8-0.21.01.0-0.90.50.7
Pavlov. Cond. index score1.72.14.92.2-1.5-2.0-2.01.9-1.90.20.71.2-0.60.01.0
Pavlov. Cond. latency score1.41.74.12.0-1.3-1.7-1.81.7-1.70.20.60.9-0.5-0.11.1
Pavlov. Cond. lever contacts1.31.63.81.9-0.9-1.7-1.42.0-1.1-0.20.61.2-0.2-0.11.6
Pavlov. Cond. magazine entry number1.62.04.5-1.91.61.91.9-1.92.1-0.1-0.8-1.11.0-0.3-0.4
Pavlov. Cond. intertrial magazine entries2.02.44.70.8-1.70.1-1.40.1-1.92.21.3-1.5-2.02.1-1.8
Pavlov. Cond. lever-magazine prob. diff.1.72.14.92.2-1.4-2.2-1.91.8-1.70.20.51.5-0.5-0.11.0
Pavlov. Cond. response bias2.63.38.52.7-1.5-2.9-2.12.2-1.9-0.20.22.2-0.4-0.41.7
Pavlov. Cond. lever latency0.20.20.6-0.80.60.60.6-0.60.6-0.2-0.1-0.30.4-0.0-0.3
Pavlov. Cond. magazine entry latency1.52.14.5-1.92.11.81.9-1.31.9-0.8-1.2-0.31.1-1.0-0.2
Pavlov. Cond. change in total contacts0.30.81.60.4-0.80.4-0.91.3-1.20.61.0-1.0-1.20.9-0.3
Pavlov. Cond. index score0.00.10.1-0.20.30.20.20.30.4-0.1-0.20.00.0-0.20.3
Pavlov. Cond. latency score0.10.20.6-0.30.60.20.50.10.7-0.4-0.60.30.4-0.60.5
Pavlov. Cond. lever contacts0.10.20.60.6-0.5-0.4-0.60.5-0.80.20.20.1-0.50.20.0
Pavlov. Cond. magazine entry number2.33.05.92.1-2.4-1.7-2.41.5-2.11.51.70.0-1.71.4-0.5
Pavlov. Cond. intertrial magazine entries5.311.523.44.5-4.8-3.7-4.73.2-3.43.63.10.3-3.02.3-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.30.50.30.30.10.5-0.2-0.40.10.2-0.40.3
Pavlov. Cond. response bias0.00.00.10.10.10.1-0.00.1-0.20.0-0.2-0.0-0.1-0.10.2
Time in closed arm before self-admin0.20.31.80.00.2-0.1-0.30.20.0-1.0-0.10.30.5-0.61.4
Time in closed arm after self-admin1.21.44.4-0.51.10.60.8-0.21.4-1.1-0.80.61.7-1.62.1
Time in open arm before self-admin1.92.36.3-1.11.3-0.21.9-1.12.5-0.7-1.71.61.9-1.81.1
Time in open arm after self-admin0.80.82.70.1-0.60.3-0.3-0.1-0.51.40.8-1.3-1.01.1-1.7
Bone: periosteal estimation3.99.225.14.8-3.9-5.0-3.93.2-1.62.71.02.3-1.40.81.7
Bone: periosteal perimeter2.14.113.33.1-2.2-3.6-2.41.5-0.22.1-0.12.30.1-0.71.9
Bone: post-yield work0.61.02.81.7-1.0-1.6-1.00.90.51.40.20.7-0.10.10.9
Progressive ratio test 1 active lever presses1.11.94.82.2-2.1-1.8-1.80.8-1.81.40.70.4-0.70.50.3
Progressive ratio test 1 breakpoint1.32.35.52.3-2.2-1.8-2.00.9-2.11.50.90.3-0.90.70.1
Progressive ratio test 1 inactive lever presses0.92.46.12.3-2.5-1.8-1.91.3-1.91.51.10.1-1.31.00.1
Progressive ratio test 2 active lever presses2.43.58.32.9-2.8-2.3-2.41.3-1.72.51.10.5-1.10.80.0
Progressive ratio test 2 breakpoint2.93.78.93.0-2.9-2.3-2.51.4-1.72.71.20.4-1.20.90.1
Progressive ratio test 2 inactive lever presses0.82.66.72.5-2.6-1.7-2.00.7-2.11.91.2-0.0-1.10.8-0.5
Incentive Sensitization - Responses0.72.05.72.2-2.1-1.6-1.91.1-0.62.40.80.3-0.90.70.0
Incentive Sensitization - Breakpoint0.92.05.72.2-2.1-1.6-1.81.2-0.52.40.90.2-0.80.60.2
Sum of active levers in priming session hrs 5-61.71.64.0-1.60.11.60.3-0.2-0.6-0.10.7-1.9-1.51.8-2.0
Progressive ratio0.10.21.00.3-0.5-0.0-0.8-0.3-0.21.0-0.4-0.10.1-0.30.1
Food seeking constrained by brief footshock2.93.67.62.1-2.6-0.5-2.22.8-1.11.62.4-1.8-2.01.70.5
Seeking ratio, punishment vs. effort0.61.43.71.2-1.3-0.7-0.81.9-0.70.41.8-0.8-1.41.5-0.0
Retroperitoneal fat weight0.31.34.42.1-1.4-1.4-1.50.7-1.21.00.70.4-0.40.20.6
Reaction time number correct0.31.24.0-0.30.9-0.10.7-2.00.80.1-1.90.61.4-1.40.5
Reaction time mean minus median0.00.20.6-0.60.50.20.70.00.8-0.50.10.2-0.00.3-0.3
Reaction time mean minus median AUC0.10.92.2-1.41.10.71.5-1.20.8-1.0-1.10.20.8-0.8-0.2
Reaction time num false alarms1.42.35.82.4-2.2-1.7-2.21.4-1.51.70.6-0.0-0.90.21.1
Reaction time num false alarms AUC1.22.66.82.6-2.3-1.8-2.41.4-1.81.70.60.1-0.90.01.2
Reaction time trials correct on left0.31.24.0-0.30.9-0.10.7-2.00.80.1-1.90.61.4-1.40.5
Reaction time trials on left0.41.24.1-0.20.8-0.20.7-2.00.80.1-2.00.71.4-1.50.5
Reaction time mean0.40.92.7-1.41.00.41.5-0.31.0-1.6-0.90.50.6-0.10.1
Reaction time mean AUC0.51.13.7-1.71.20.61.7-0.21.0-1.9-0.70.30.40.1-0.1
Median of all reaction times0.61.03.3-1.41.00.31.5-0.30.9-1.8-1.00.60.7-0.20.2
Reaction time omissions0.30.52.60.7-0.2-1.60.1-0.10.2-0.3-0.61.6-0.0-0.20.1
Reaction time false alarm rate2.02.75.32.3-2.2-1.5-2.32.3-1.61.21.5-0.2-1.30.90.9
Reaction time premature initiation rate0.71.22.31.0-1.5-0.9-1.40.4-1.50.80.90.3-1.30.9-1.1
Reaction time premature initiations0.20.61.40.9-1.1-0.8-1.1-0.6-1.21.0-0.00.3-0.70.0-0.9
Std. dev. reaction times0.10.31.0-0.80.80.31.0-0.00.8-1.0-0.30.40.20.0-0.1
Reaction time trials completed0.41.24.1-0.20.8-0.20.7-2.00.80.1-2.00.71.4-1.50.5
Reaction time trials AUC0.31.24.0-0.20.9-0.00.7-2.00.70.1-1.90.61.3-1.40.5
Run reversals in cocaine runway, females0.30.41.9-0.10.3-0.70.8-0.61.4-0.3-0.00.70.7-0.4-0.3
Run reversals in cocaine runway, males0.40.41.9-0.40.6-0.50.4-0.51.40.2-0.61.00.7-0.40.0
Latency to leave start box in cocaine runway0.20.20.6-0.70.60.10.7-0.40.8-0.4-0.30.40.4-0.1-0.1
Latency to leave start box in cocaine runway, F0.91.22.8-1.01.1-0.51.1-0.91.7-0.8-1.11.51.2-0.80.4
Latency to leave start box in cocaine runway, M0.70.61.70.0-0.50.9-0.40.9-0.8-0.01.0-1.3-1.10.9-0.6
Std. dev. time between licks in bursts0.10.10.4-0.10.10.4-0.0-0.1-0.20.40.6-0.6-0.20.5-0.6
Total sessions with >9 infusions0.20.30.90.7-0.8-0.2-0.3-0.4-1.00.60.4-0.4-0.10.2-0.3
Short access day 1 total inactive lever presses0.91.75.72.0-1.8-2.4-1.20.8-0.70.60.31.50.3-0.51.3
Short access day 10 total inactive lever presses0.10.52.20.3-0.8-0.8-0.4-0.0-0.40.30.60.1-0.80.9-1.5
Short access day 1 total infusions0.30.52.40.7-1.2-0.6-0.6-0.3-1.60.40.3-0.1-0.60.5-0.7
Short access day 10 total infusions1.32.25.62.2-2.4-1.4-1.71.2-1.91.41.4-0.5-1.11.00.1
Short access total infusions0.81.13.11.4-1.8-1.2-1.20.6-1.50.70.8-0.1-0.90.8-0.1
Short access day 1 locomotion1.01.63.21.7-1.8-1.6-1.20.0-1.71.50.90.5-0.81.0-1.1
Short access day 10 total locomotion1.25.010.63.3-3.1-1.9-2.92.7-2.41.62.6-0.3-1.61.21.1
Short access total locomotion1.42.15.42.3-2.2-1.6-1.81.2-1.81.31.60.2-0.80.80.3
One hour access (0.3 mA shock)0.60.71.71.0-1.1-0.9-0.90.8-0.31.30.7-0.1-0.91.0-0.4
Compulsive drug intake1.01.53.1-1.01.1-0.31.0-1.21.7-0.7-1.81.41.4-1.60.7
One hour access (shock baseline)0.61.72.51.5-1.5-0.3-1.21.3-1.41.51.6-1.2-1.31.4-0.4
Social response proportion0.30.31.5-0.20.80.50.5-0.71.20.7-0.2-0.30.60.00.1
Social responses0.10.10.60.10.10.4-0.10.2-0.20.40.5-0.7-0.30.40.3
Social time0.20.43.0-0.1-0.1-0.60.20.31.70.70.20.50.10.6-0.1
Soleus weight0.10.20.50.6-0.3-0.6-0.5-0.00.20.70.10.6-0.1-0.2-0.1
Bone: stiffness0.30.61.61.3-0.4-0.7-0.4-0.5-0.31.1-1.00.20.6-0.90.9
Tibialis anterior weight0.93.18.70.1-0.71.5-1.40.6-1.12.02.9-2.3-2.02.1-2.3
Time to tail flick, vehicle, before self-admin1.72.15.5-0.40.7-1.11.3-0.61.9-0.2-2.02.41.6-1.81.3
Time to tail flick, vehicle, after self-admin0.20.41.10.0-0.5-0.8-0.2-0.9-0.10.7-1.00.80.3-0.7-0.6
Time to tail flick, test, before self-admin0.30.30.7-0.60.20.60.30.80.8-0.60.7-0.5-0.30.60.2
Time to tail flick, test, after self-admin0.00.00.1-0.0-0.3-0.2-0.30.1-0.3-0.1-0.10.0-0.20.1-0.2
Delta time to tail flick, vehicle, before/after SA1.51.63.51.1-1.6-0.5-1.90.9-1.71.01.3-1.0-1.51.2-1.0
Delta time to tail flick, test, before/after SA0.10.10.50.1-0.1-0.0-0.2-0.5-0.60.3-0.7-0.20.2-0.60.1
Tibia length1.02.77.91.00.9-0.90.5-1.60.4-0.2-2.31.62.2-2.82.5
Ambulatory time before self-admin0.30.82.1-0.80.6-0.50.4-0.51.5-0.3-1.31.11.0-1.00.9
Ambulatory time after self-admin0.00.10.2-0.30.5-0.1-0.10.10.3-0.1-0.40.20.0-0.20.5
Bone: tissue strength1.61.73.3-0.71.50.91.6-1.81.0-0.6-1.80.41.8-1.51.0
Total heroin consumption0.30.31.40.2-0.5-0.8-0.31.1-0.3-0.5-0.20.5-0.20.21.2
Bone: trabecular number1.42.610.02.1-1.2-3.2-1.30.5-1.3-0.1-1.22.70.4-1.31.4
Bone: trabecular spacing1.01.55.9-1.10.12.30.40.30.50.61.4-2.4-0.71.3-1.0
Bone: trabecular thickness2.13.012.92.1-1.0-3.6-1.40.2-0.40.4-1.13.20.7-1.21.1
Bone: trabecular tissue density1.93.28.7-0.21.6-0.41.5-2.90.7-0.6-2.91.52.6-2.40.7
Water consumed over 24 hours0.10.31.20.90.1-0.4-0.2-0.0-0.3-0.1-0.20.50.8-0.41.1
Number of responses in last shaping day0.40.52.70.3-0.4-1.50.2-0.00.5-0.2-0.31.60.4-0.10.2