Hub : Genes

Ddx42

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Ddx42 0.02 0.01 7.7e-03 0.02 0.01 0.01 0.01 3.3e-03 3.9e-02 1.5e-02 1.8e-02
2 Adipose gene expression Ddx42 0.12 0.05 4.2e-10 0.04 0.06 0.06 0.06 6.0e-05 4.6e-07 4.3e-07 1.1e-07
3 PL mRNA stability Ddx42 0.02 0.01 2.7e-03 0.01 0.02 0 0.01 1.2e-02 6.1e-03 1.3e-01 4.2e-02
4 RMTg mRNA stability Ddx42 0.22 0.09 2.9e-05 0.15 0.15 0.15 0.14 8.4e-05 8.5e-05 9.1e-05 1.0e-04
5 LHb mRNA stability Ddx42 0.53 0.13 2.6e-05 0.04 0.17 0.12 0.14 3.2e-02 9.1e-05 7.2e-04 3.2e-04
6 Liver gene expression Ddx42 0.07 0.04 1.1e-04 0.04 0.04 0.02 0.03 3.9e-05 6.5e-05 1.3e-03 1.2e-04
7 Adipose mRNA stability Ddx42 0.12 0.05 1.3e-12 0.05 0.11 0.12 0.11 1.2e-06 3.5e-12 2.0e-13 1.8e-12
8 Brain mRNA stability Ddx42 0.07 0.03 1.7e-05 0.01 0.05 0.02 0.03 1.7e-02 1.1e-05 6.9e-03 6.7e-04
9 BLA mRNA stability Ddx42 0.1 0.05 4.0e-05 0.12 0.05 0.06 0.08 5.3e-07 1.5e-03 3.9e-04 3.3e-05
10 Liver mRNA stability Ddx42 0.05 0.03 1.9e-03 0.03 0.02 0.02 0.02 1.0e-04 5.8e-03 1.6e-03 1.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density2.23.710.62.1-3.30.7-0.5-2.13.10.9-1.5-0.52.1
Area under the delay curve0.20.20.60.4-0.70.50.1-0.40.70.4-0.7-0.2-0.2
BMI with tail0.51.64.00.50.31.42.01.8-1.1-0.11.20.9-1.8
BMI without tail1.32.77.42.1-1.02.71.12.5-1.0-1.21.60.2-1.5
Body weight0.93.813.23.6-1.93.5-0.52.3-0.5-0.51.5-1.10.2
Weight adjusted by age0.40.51.8-1.21.0-0.30.40.2-0.7-0.1-0.20.0-1.3
Bone surface4.17.221.93.9-4.72.0-2.0-1.43.50.6-1.0-1.63.1
Bone volume3.56.019.03.5-4.41.9-1.6-1.43.30.5-1.0-1.42.5
Breakpoint value in progressive ratio session0.80.93.10.3-0.10.6-0.81.0-1.2-1.81.2-0.8-0.3
Number of licking bursts0.10.10.2-0.1-0.0-0.20.0-0.40.20.4-0.40.30.3
Context. condit. distance diff. score0.60.82.2-0.61.4-0.10.61.1-1.5-0.40.80.6-0.6
Locomotion velocity, session 11.31.43.51.7-1.80.6-0.3-0.71.30.7-0.5-0.61.9
Locomotion distance, session 10.60.81.41.0-0.80.20.9-0.61.01.0-1.10.41.2
Locomotion velocity, session 20.20.30.80.4-0.7-0.2-0.70.00.6-0.60.2-0.10.9
Locomotion distance, session 20.20.31.40.40.3-0.40.7-0.00.00.4-0.50.61.2
Locomotion velocity, session 30.81.02.3-0.6-0.0-0.91.5-1.00.81.0-1.01.50.5
Locomotion distance, session 30.50.50.9-0.1-0.5-0.40.5-0.90.90.8-0.80.71.0
Stereotopy head waving bouts, day 30.50.51.7-0.3-0.4-0.50.8-1.31.00.6-1.00.40.0
Stereotopy head waving duration, day 30.20.20.6-0.50.3-0.40.8-0.6-0.10.3-0.60.5-0.5
Locomotion velocity, session 70.30.30.6-0.40.3-0.70.5-0.70.40.8-0.40.50.6
Locomotion distance, session 70.10.20.6-0.10.50.10.30.8-0.4-0.50.20.3-0.6
Stereotopy head waving bouts, day 70.70.81.6-0.6-0.0-1.11.0-1.20.80.7-1.11.30.8
Stereotopy head waving duration, day 71.41.74.2-1.61.1-2.10.9-1.60.11.0-1.31.50.9
Locomotion velocity, session 80.70.81.60.80.60.6-1.01.0-1.2-0.11.3-0.80.9
Locomotion distance, session 80.40.61.8-0.11.2-0.00.41.1-1.4-0.70.60.3-0.2
Degree of sensitization distance1.01.02.70.70.71.0-0.61.7-1.3-1.01.0-0.8-1.0
Degree of sensitization stereotypy1.21.43.5-1.10.7-1.71.3-1.00.30.9-0.91.91.2
Conditioned locomotion1.21.43.90.40.11.1-1.01.5-1.0-2.01.2-0.9-1.5
Cocaine response after cond. corrected0.70.81.9-0.3-0.6-0.50.3-1.31.41.4-1.30.20.5
Cocaine response after cond. not corrected2.12.35.1-0.6-0.9-1.30.5-2.32.21.9-1.90.71.5
Cocaine response before conditioning0.70.91.9-0.5-0.5-1.10.5-1.41.10.7-1.01.01.1
Saline control response2.53.37.90.70.11.6-1.12.7-1.7-2.82.5-1.0-1.9
Bone: connectivity density2.23.510.42.4-3.20.9-0.9-1.62.80.5-1.2-0.72.2
Bone: cortical apparent density2.43.18.0-2.31.7-1.92.8-1.5-0.11.1-1.62.2-1.0
Bone: cortical area1.72.69.51.9-3.11.20.7-1.02.60.5-1.10.51.0
Bone: cortical porosity4.34.716.52.8-4.11.7-2.2-0.32.8-0.60.8-1.32.2
Bone: cortical porosity2.83.011.32.3-3.41.3-1.1-0.72.60.20.1-0.41.9
Bone: cortical thickness5.28.620.6-1.8-0.6-2.24.5-3.52.93.0-3.43.90.5
Bone: cortical thickness4.65.411.2-1.7-0.3-2.33.3-2.62.32.2-2.53.21.0
Bone: cortical tissue density2.22.97.1-2.21.7-1.82.7-1.3-0.21.0-1.52.0-1.0
Condit. Reinf. active minus inactive responses1.31.42.71.5-1.51.5-1.11.30.2-1.61.2-0.80.0
Condit. Reinf. active-inactive response ratio0.50.61.20.9-1.00.7-0.80.80.1-1.10.8-0.40.3
Condit. Reinf. active responses1.72.14.01.9-1.41.9-1.51.5-0.1-2.01.4-1.2-0.3
Condit. Reinf. inactive responses0.50.62.01.4-0.71.3-0.70.5-0.0-0.70.2-0.9-0.2
Incentive salience index mean1.01.23.11.7-1.81.1-1.20.50.7-1.10.7-0.80.8
Condit. Reinf. lever presses0.20.31.10.7-0.60.1-0.7-0.30.5-0.30.2-0.21.1
Condit. Reinf. active minus inactive responses2.32.89.92.8-3.11.7-1.10.11.7-0.7-0.4-0.61.7
Condit. Reinf. active-inactive response ratio2.22.37.62.1-2.81.1-1.4-0.41.8-0.3-0.2-0.81.8
Condit. Reinf. active responses2.33.27.82.8-2.82.4-1.51.30.8-1.90.7-1.30.2
Condit. Reinf. inactive responses1.61.95.11.2-0.61.7-0.42.0-0.8-2.31.2-0.7-1.6
Condit. Reinf. lever presses0.60.82.21.4-1.51.0-0.40.70.6-1.00.6-0.10.6
Condit. Reinf. lever reinforcers received2.02.97.92.6-2.82.3-1.41.01.0-1.70.5-1.30.2
Conditioned reinforcement - actives0.60.61.41.1-0.11.1-0.51.0-1.2-0.40.9-0.3-0.1
Conditioned reinforcement - inactives0.60.72.71.6-1.11.2-0.30.50.4-0.00.5-0.10.6
Conditioned locomotion1.31.64.92.2-1.61.9-1.20.90.2-0.50.9-1.20.4
Patch foraging indifference point 0 sec2.03.38.83.0-1.92.8-1.02.0-0.1-2.11.2-1.3-0.2
Patch foraging indifference point AUC1.01.11.81.0-0.11.3-0.81.3-1.0-1.21.2-1.3-0.8
Delay disc. indifference point, 0s delay0.30.30.9-1.00.5-0.50.1-0.70.00.1-0.90.0-0.9
Delay disc. indifference point, 16s delay0.50.51.40.5-1.21.00.30.00.9-0.3-0.4-0.0-1.0
Delay disc. indifference point, 2s delay0.80.82.11.0-1.10.7-0.4-0.91.00.9-1.4-0.70.7
Delay disc. indifference point, 24s delay1.11.03.81.7-1.11.9-0.01.00.0-0.60.4-0.7-0.7
Delay disc. indifference point, 4s delay1.11.22.4-0.8-0.4-0.90.5-1.51.61.5-1.50.60.6
Delay disc. indifference point, 8s delay0.50.51.50.0-0.6-0.00.5-0.91.10.7-1.20.0-0.2
Indifference point function ln k0.81.22.3-0.4-0.8-0.61.2-1.41.50.7-1.41.50.2
Indifference point function log k0.81.22.3-0.4-0.8-0.61.2-1.41.50.7-1.41.50.2
Patch foraging total patch changes 0 sec2.23.59.53.1-2.22.9-1.12.00.1-2.01.1-1.4-0.2
Patch foraging total patch changes 12 sec3.84.97.82.6-0.62.7-2.32.8-1.7-2.72.1-2.6-0.5
Patch foraging total patch changes 18 sec1.72.24.11.8-1.12.0-1.12.0-0.4-1.91.6-1.3-0.4
Patch foraging total patch changes 24 sec1.51.96.42.5-1.92.2-0.61.10.3-1.20.4-1.00.1
Patch foraging total patch changes 6 sec1.11.64.22.0-1.51.9-0.81.20.2-1.40.8-1.00.0
Patch foraging time to switch 0 sec0.10.20.6-0.60.5-0.8-0.5-0.3-0.10.20.20.00.5
Patch foraging water rate 0 sec0.81.34.52.1-1.81.9-0.00.80.8-0.50.5-0.60.4
Patch foraging water rate 12 sec2.33.66.2-0.7-0.8-1.22.4-2.02.32.5-2.32.21.2
Patch foraging water rate 18 sec1.92.54.20.3-1.2-0.71.7-1.82.01.7-2.11.61.8
Patch foraging water rate 24 sec0.60.92.70.3-0.4-0.40.7-0.70.81.4-1.10.81.7
Patch foraging water rate 6 sec1.31.94.80.3-1.6-0.21.2-1.72.21.4-1.81.11.1
Seeking ratio, delayed vs. immediate footshock0.50.61.40.30.40.50.01.2-1.0-0.81.10.1-0.8
Distance traveled before self-admin0.70.81.3-1.1-0.2-0.80.2-1.10.81.1-1.10.90.7
Distance traveled after self-admin0.20.20.7-0.90.4-0.60.0-0.1-0.10.2-0.20.90.4
Extensor digitorum longus weight1.87.016.5-2.43.80.30.32.7-3.9-1.42.8-0.7-4.1
Bone: elastic displacement2.63.05.7-0.90.1-1.72.1-2.21.42.4-1.81.91.6
Bone: elastic work1.51.93.80.7-1.4-0.31.0-1.81.91.8-1.10.81.9
Bone: endosteal estimation7.215.633.35.8-4.84.8-5.32.90.9-3.22.9-4.41.6
Bone: endosteal perimeter7.716.036.86.1-4.95.2-5.12.80.9-2.92.7-4.41.5
Epididymis fat weight0.81.95.31.9-1.32.3-1.11.3-0.0-0.81.3-1.7-1.0
Delta time in closed arm before/after self-admin0.80.83.60.3-0.3-0.6-0.2-1.01.01.1-0.70.21.9
Delta time in open arm before/after self-admin1.61.66.4-0.91.20.30.21.1-1.8-1.30.80.1-2.5
Diff in mean of infusions in LGA sessions0.50.61.4-1.11.1-0.71.20.1-0.70.10.20.7-0.4
Delay discount exponential model param0.30.30.7-0.70.8-0.70.20.3-0.7-0.40.60.4-0.1
Extinction: sum of active levers before priming1.51.53.60.10.60.9-0.41.5-1.7-1.91.2-0.6-1.6
Active lever presses in extinction session 61.51.42.71.2-1.51.5-1.31.10.3-1.71.3-1.0-0.4
Bone: final force1.62.66.61.5-2.40.40.7-1.62.61.3-1.80.51.7
Bone: final moment1.82.97.31.5-2.60.40.7-1.82.71.4-1.80.51.9
Food consumed during 24 hour testing period2.22.75.52.3-0.72.4-1.22.1-1.1-1.32.0-1.6-0.1
Glucose0.50.82.5-1.61.0-1.10.8-0.6-0.20.8-0.61.1-0.4
Heart weight0.10.20.80.0-0.00.40.80.30.00.4-0.30.9-0.4
Delay discount hyperbolic model param0.30.30.6-0.60.8-0.60.10.4-0.7-0.50.80.4-0.0
Intermittent access intake day 1-15 change0.70.72.40.10.00.4-1.50.9-0.4-0.91.4-1.00.1
Intermittent access intake escalation0.40.41.2-0.10.30.0-1.10.6-0.4-0.41.1-0.60.2
Intermittent access intake escalation 20.80.83.10.6-0.30.6-1.70.7-0.2-0.71.3-1.20.4
Intermitt. access day 1 inactive lever presses2.02.26.72.2-2.61.7-1.00.61.7-1.20.4-0.80.7
Intermitt. access day 15 inactive lever presses2.22.46.91.6-2.61.7-1.20.62.0-1.61.1-1.2-0.7
Intermitt. access escalation Index2.32.03.9-2.01.8-1.91.0-1.1-0.61.4-1.41.50.5
Intermittent access day 1 total infusions0.40.51.71.3-1.01.20.50.40.20.3-0.10.10.2
Intermittent access day 15 total infusions0.50.61.21.0-0.11.1-0.51.1-0.9-0.11.0-0.30.0
Intermittent access terminal intake (last 3 days)1.41.63.71.9-1.01.9-1.31.4-0.6-0.71.4-1.00.0
Intermittent access total infusions1.31.45.02.2-1.21.9-0.71.2-0.5-0.41.0-0.60.5
Intermittent access day 1 locomotion1.81.97.22.7-1.92.1-0.50.80.20.10.7-0.91.1
Intermittent access day 15 total locomotion2.72.910.03.2-1.42.4-1.51.5-0.8-0.41.5-1.41.4
Intermittent access total locomotion3.74.215.43.9-2.53.0-1.31.6-0.0-0.61.6-1.51.4
Intermittent access standard deviation0.90.92.41.5-1.31.3-0.70.80.6-0.41.2-0.60.6
Left kidney weight1.33.510.2-0.7-0.1-1.03.2-1.41.22.3-2.33.00.9
Right kidney weight1.23.36.50.2-0.5-0.92.4-1.81.52.5-2.32.22.1
Cocaine induced anxiety1.21.44.7-0.1-1.4-0.31.0-1.42.21.1-1.30.80.6
Post-drug Anxiety1.31.45.4-0.4-1.3-0.40.8-1.62.31.2-1.30.40.4
Baseline Anxiety0.40.40.8-0.90.5-0.80.6-0.80.30.9-0.80.50.0
Tail length1.13.39.93.1-2.12.6-1.91.30.2-1.11.1-1.80.8
Length with tail1.03.711.13.3-2.32.3-2.40.30.80.10.3-2.12.1
Length without tail0.61.33.51.2-0.90.2-1.5-1.11.11.1-0.6-1.21.9
Times rat made contact with spout0.50.61.81.4-0.80.8-0.70.30.10.20.4-0.71.2
Lifetime Intake1.41.65.42.3-1.52.1-0.41.3-0.2-0.81.0-0.30.1
Liver weight, left0.30.41.31.1-0.70.6-0.9-0.30.10.0-0.3-0.90.8
Liver weight, right1.62.76.70.1-0.7-0.71.8-2.22.02.3-2.61.11.0
Locomotor activity0.50.91.91.10.10.31.31.0-0.9-0.40.51.41.1
Locomotor testing distance1.01.64.41.5-0.51.20.52.1-1.2-1.71.60.60.1
Locomotor testing rearing1.52.36.61.20.20.9-0.62.6-1.9-2.02.5-0.10.4
Locomotion in novel chamber0.91.24.50.3-0.3-0.6-0.0-1.00.81.9-1.00.12.1
Locomotion in novel chamber post-restriction1.01.22.31.5-1.51.5-1.5-0.10.40.0-0.3-1.40.5
Fecal boli incidents, locomotor time 10.50.52.0-0.60.30.4-0.50.5-0.6-1.00.4-0.9-1.4
Change in fecal boli incidents, locomotor task0.20.10.70.0-0.10.10.5-0.10.40.4-0.30.2-0.8
Time >=10cm from walls, locomotor time 12.12.14.2-1.81.4-2.01.3-1.2-0.01.6-1.41.70.8
Bouts of movement, locomotor time 10.10.10.2-0.50.1-0.20.4-0.20.3-0.00.10.2-0.5
Total resting periods, locomotor time 10.10.10.4-0.5-0.0-0.30.4-0.40.60.2-0.10.0-0.4
Rest time, locomotor task time 10.30.41.0-0.8-0.2-0.4-0.4-0.70.7-0.5-0.4-0.5-1.0
Distance moved, locomotor task time 10.60.62.31.5-0.50.8-0.10.50.10.80.4-0.11.4
Vertical activity count, locomotor time 10.70.72.41.2-0.90.30.2-0.30.91.2-0.30.31.5
Time >=10cm from walls, locomotor time 20.70.82.7-0.5-0.4-1.0-0.1-1.11.01.0-0.40.41.6
Bouts of movement, locomotor time 20.50.63.2-0.90.20.10.30.4-0.0-1.00.50.2-1.8
Total resting periods, locomotor time 20.60.63.2-1.20.4-0.30.50.20.0-0.90.20.4-1.8
Rest time, locomotor task time 21.92.18.0-2.81.5-1.51.0-1.0-0.1-0.1-1.20.8-2.1
Distance moved, locomotor task time 21.01.16.41.5-0.80.2-0.5-0.00.61.00.6-0.02.5
Vertical activity count, locomotor time 21.61.75.02.2-1.81.3-1.20.80.6-0.71.4-0.81.5
Light reinforcement 10.61.25.50.3-0.51.20.70.9-0.2-1.70.30.1-2.4
Light reinforcement 20.81.03.80.5-1.41.10.00.00.9-1.4-0.1-0.6-1.9
Bone: marrow area7.015.232.55.7-4.74.7-5.22.80.9-3.12.9-4.31.7
Bone: maximum diameter2.44.416.03.2-4.02.5-1.6-0.12.3-0.7-0.2-1.41.0
Bone: maximum force1.52.58.02.3-2.81.50.4-0.72.20.8-1.20.01.3
Bone: maximum moment1.62.78.82.3-3.01.40.3-0.92.40.8-1.2-0.01.5
Mean time between licks in bursts0.10.20.60.2-0.00.8-0.30.5-0.40.10.2-0.6-0.6
Mean num. licks in bursts0.40.40.90.8-0.40.9-0.40.8-0.3-0.50.8-0.8-0.2
Cd content in liver1.51.66.8-1.92.6-1.60.60.1-1.40.6-0.00.2-0.5
Co content in liver1.11.24.0-1.12.0-0.7-0.30.9-1.9-0.61.3-0.2-0.5
Cu content in liver0.40.51.20.2-0.60.7-0.90.30.1-1.10.6-0.9-0.8
Fe content in liver0.30.30.9-0.90.7-0.60.60.1-0.4-0.4-0.20.6-0.6
K content in liver0.30.31.30.7-0.30.5-1.2-0.2-0.1-0.4-0.2-0.90.3
Mg content in liver0.50.61.3-0.20.70.1-1.2-0.0-0.8-1.00.3-1.1-0.9
Mn content in liver0.70.72.80.2-0.4-0.50.3-1.40.80.7-1.70.30.9
Na content in liver0.20.21.1-0.20.10.1-0.60.2-0.5-1.00.1-0.1-0.5
Rb content in liver1.72.14.9-2.22.0-2.21.0-1.2-0.60.9-1.41.2-0.1
Se content in liver0.81.03.0-1.51.7-1.00.8-0.2-1.10.2-0.70.6-1.1
Sr content in liver0.80.71.70.9-1.30.30.3-0.71.20.8-0.60.31.0
Zn content in liver0.40.51.70.2-0.4-0.10.6-1.20.40.7-1.30.20.2
Bone: minimum diameter6.111.429.85.5-4.84.7-3.61.91.4-2.02.0-3.31.2
Time in familiar zone, hab. session 12.12.03.60.70.61.2-1.71.9-1.5-1.51.7-1.6-0.9
Time in novel zone, hab. session 12.12.03.6-1.2-0.5-1.31.9-1.71.61.4-1.51.80.5
Total zone transitions, hab. session 10.30.41.31.20.10.40.80.5-0.20.70.10.41.1
Total locomotion distance, hab. session 11.41.95.92.1-1.60.60.9-0.61.61.2-0.70.52.4
Locomotion velocity, hab. session 11.31.85.92.4-1.60.80.4-0.31.31.0-0.50.12.4
Time in familiar zone, hab. session 22.12.14.70.80.71.1-1.42.2-1.9-1.82.0-1.2-0.5
Time in novel zone, hab. session 23.03.06.3-0.7-1.2-1.11.5-2.52.52.1-2.41.20.8
Total zone transitions, hab. session 20.20.31.00.50.80.10.40.8-1.0-0.10.50.30.5
Total locomotion distance, hab. session 20.30.41.91.4-0.10.80.30.7-0.3-0.30.3-0.20.4
Locomotion velocity, hab. session 20.30.32.01.4-0.10.80.30.6-0.2-0.10.1-0.20.5
Novel to familiar place preference ratio0.20.20.90.5-0.90.6-0.2-0.20.60.1-0.1-0.1-0.2
Novelty place preference0.10.10.50.2-0.70.3-0.0-0.30.60.2-0.20.1-0.1
Time in novel zone, NPP test0.20.20.60.1-0.70.00.2-0.50.70.4-0.40.40.1
Total zone transitions, NPP test0.40.61.80.90.10.11.3-0.10.00.9-0.80.81.1
Total locomotion distance, NPP test0.81.23.91.9-1.10.50.5-0.31.00.9-0.60.12.0
Locomotion velocity, NPP test0.40.63.01.7-0.70.90.60.30.50.5-0.3-0.00.9
Intraocular pressure1.11.53.61.0-0.71.90.21.7-0.4-1.41.2-0.5-1.8
Delta distance traveled before/after self-admin0.30.41.3-0.50.7-0.60.80.3-0.4-0.40.21.1-0.2
Delta ambulatory time before/after self-admin0.10.10.40.10.2-0.00.10.4-0.2-0.60.20.2-0.2
Parametrial fat weight1.22.46.02.1-2.41.3-1.1-1.22.10.8-0.6-1.41.2
Pavlov. Cond. lever latency1.11.44.4-1.92.1-0.70.30.5-1.5-0.00.0-0.1-1.9
Pavlov. Cond. magazine entry latency1.51.95.52.2-2.41.5-1.30.31.2-1.10.6-0.91.1
Pavlov. Cond. change in total contacts1.21.33.91.7-2.01.1-1.00.21.0-1.10.9-0.60.8
Pavlov. Cond. index score1.21.55.02.0-2.21.3-0.90.11.2-0.80.5-0.51.2
Pavlov. Cond. latency score0.91.23.61.8-1.91.1-0.70.11.0-0.60.5-0.21.2
Pavlov. Cond. lever contacts0.80.92.61.5-1.60.7-0.7-0.10.9-0.30.6-0.31.4
Pavlov. Cond. magazine entry number1.21.45.0-1.72.2-1.21.00.0-1.31.1-0.40.7-0.7
Pavlov. Cond. intertrial magazine entries1.72.14.91.00.31.9-0.52.2-1.6-1.71.2-0.9-1.9
Pavlov. Cond. lever-magazine prob. diff.1.21.55.31.9-2.31.2-0.8-0.11.4-0.60.3-0.31.1
Pavlov. Cond. response bias1.92.38.42.1-2.91.1-1.0-0.62.1-0.60.0-0.61.5
Pavlov. Cond. lever latency0.10.10.2-0.40.4-0.20.0-0.2-0.10.30.1-0.2-0.5
Pavlov. Cond. magazine entry latency1.71.94.2-2.01.8-2.01.1-1.0-0.61.3-1.21.50.2
Pavlov. Cond. change in total contacts0.30.51.50.40.50.3-0.61.0-1.2-0.90.6-0.4-0.0
Pavlov. Cond. index score0.10.20.5-0.40.3-0.60.3-0.2-0.20.2-0.40.70.5
Pavlov. Cond. latency score0.30.30.9-0.50.2-0.80.4-0.40.00.4-0.60.90.7
Pavlov. Cond. lever contacts0.10.10.30.5-0.40.30.10.30.1-0.3-0.00.20.4
Pavlov. Cond. magazine entry number2.32.85.52.2-1.82.3-1.61.40.3-1.71.6-2.0-0.7
Pavlov. Cond. intertrial magazine entries8.811.522.84.3-3.64.8-3.72.70.5-3.53.0-4.1-1.2
Pavlov. Cond. lever-magazine prob. diff.0.20.20.6-0.50.4-0.70.4-0.3-0.20.4-0.60.80.5
Pavlov. Cond. response bias0.10.10.2-0.00.1-0.20.3-0.1-0.10.2-0.50.50.4
Time in closed arm before self-admin1.31.53.5-1.00.5-1.51.6-1.00.41.2-0.91.91.3
Time in closed arm after self-admin1.81.97.0-0.71.1-1.80.5-1.3-0.11.8-1.00.72.7
Time in open arm before self-admin0.50.61.8-0.60.1-0.80.2-0.90.81.3-0.60.31.0
Time in open arm after self-admin1.11.24.9-0.0-0.01.2-0.61.2-0.8-1.21.1-0.8-2.2
Bone: periosteal estimation4.49.126.94.8-5.23.7-2.90.92.5-1.60.9-2.51.7
Bone: periosteal perimeter2.64.415.93.2-4.02.2-1.4-0.42.50.0-0.3-1.11.9
Bone: post-yield work1.11.44.02.0-1.61.5-1.30.70.5-0.30.7-1.21.0
Progressive ratio test 1 active lever presses1.71.87.12.7-1.82.2-0.51.1-0.1-0.80.6-0.60.5
Progressive ratio test 1 breakpoint2.52.68.22.9-1.92.6-0.71.6-0.3-1.51.1-0.9-0.1
Progressive ratio test 1 inactive lever presses1.71.95.72.4-1.62.2-0.41.5-0.3-1.50.8-0.1-0.2
Progressive ratio test 2 active lever presses2.52.68.62.9-2.12.6-1.41.10.1-0.90.9-1.40.3
Progressive ratio test 2 breakpoint2.93.29.33.1-2.42.7-1.71.20.1-1.11.2-1.60.4
Progressive ratio test 2 inactive lever presses2.22.68.52.9-1.92.7-1.01.4-0.1-1.01.1-1.1-0.3
Incentive Sensitization - Responses1.81.84.52.1-1.52.0-1.71.0-0.2-0.90.9-1.50.2
Incentive Sensitization - Breakpoint1.61.74.22.1-1.41.8-1.70.8-0.2-0.70.8-1.50.4
Sum of active levers in priming session hrs 5-61.51.54.0-1.11.4-0.10.41.0-2.0-1.60.8-0.0-1.7
Progressive ratio0.10.10.40.10.3-0.1-0.4-0.5-0.10.6-0.6-0.30.3
Food seeking constrained by brief footshock2.83.47.32.1-0.31.7-2.72.1-1.5-1.82.4-2.00.4
Seeking ratio, punishment vs. effort1.01.33.11.1-0.61.1-1.11.5-0.5-1.51.8-0.9-0.1
Retroperitoneal fat weight0.93.011.23.4-1.62.3-1.51.40.1-0.41.4-1.81.4
Reaction time number correct1.11.64.0-0.50.0-0.71.5-1.30.82.0-2.01.40.7
Reaction time mean minus median0.10.20.5-0.70.4-0.4-0.4-0.10.1-0.10.2-0.4-0.5
Reaction time mean minus median AUC0.60.71.9-1.40.9-1.10.7-0.90.20.7-1.00.6-0.3
Reaction time num false alarms1.01.34.42.1-1.61.7-0.80.90.2-0.80.6-0.40.8
Reaction time num false alarms AUC1.21.65.52.4-1.91.8-1.10.70.4-0.70.5-0.80.9
Reaction time trials correct on left1.11.64.0-0.50.0-0.71.5-1.30.82.0-2.01.40.7
Reaction time trials on left1.11.64.1-0.4-0.1-0.71.5-1.30.92.0-2.01.30.7
Reaction time mean0.40.61.8-1.30.6-1.30.1-0.90.50.2-0.70.40.1
Reaction time mean AUC0.50.72.8-1.70.9-1.50.1-0.80.40.0-0.50.5-0.1
Median of all reaction times0.50.72.0-1.30.6-1.40.2-0.90.60.3-0.80.60.2
Reaction time omissions0.50.73.40.2-1.30.1-0.4-0.91.80.3-0.8-0.6-0.1
Reaction time false alarm rate1.52.14.62.1-1.51.8-1.71.2-0.0-1.51.4-1.20.6
Reaction time premature initiation rate0.70.91.91.0-1.21.40.00.9-0.1-1.40.8-0.5-1.3
Reaction time premature initiations0.30.41.00.7-1.01.00.70.20.1-0.3-0.20.1-0.9
Std. dev. reaction times0.20.30.8-0.90.4-0.7-0.7-0.60.50.1-0.1-0.5-0.2
Reaction time trials completed1.11.64.1-0.4-0.1-0.71.5-1.30.92.0-2.01.30.7
Reaction time trials AUC1.11.64.2-0.40.1-0.71.5-1.30.82.0-2.01.30.7
Run reversals in cocaine runway, females0.40.42.1-0.1-0.6-0.00.4-0.61.50.80.1-0.2-0.0
Run reversals in cocaine runway, males0.30.31.2-0.4-0.6-0.20.3-0.71.10.5-0.60.00.1
Latency to leave start box in cocaine runway0.30.30.8-0.90.1-0.70.6-0.50.40.5-0.50.5-0.0
Latency to leave start box in cocaine runway, F1.11.21.9-1.2-0.2-1.11.2-1.11.21.3-1.21.40.6
Latency to leave start box in cocaine runway, M0.40.41.0-0.10.60.0-0.70.4-1.0-0.60.7-0.8-0.5
Std. dev. time between licks in bursts0.20.30.7-0.10.20.4-0.10.7-0.4-0.70.6-0.3-0.8
Total sessions with >9 infusions0.50.62.40.8-0.20.61.50.4-0.40.2-0.31.3-0.3
Short access day 1 total inactive lever presses0.80.82.21.3-1.50.60.3-0.21.20.5-0.30.71.4
Short access day 10 total inactive lever presses1.01.12.70.6-0.91.2-0.71.00.5-1.71.0-0.9-1.5
Short access day 1 total infusions0.80.91.41.2-0.51.21.21.1-0.7-0.90.31.1-0.7
Short access day 10 total infusions2.83.18.12.8-2.22.8-0.81.80.2-1.71.7-0.9-0.3
Short access total infusions1.41.64.12.0-1.51.90.21.5-0.2-1.51.10.3-0.2
Short access day 1 locomotion1.92.06.02.3-1.62.50.11.6-0.2-1.21.1-0.5-0.9
Short access day 10 total locomotion5.86.516.74.1-2.43.7-2.12.6-0.6-1.92.8-2.40.7
Short access total locomotion2.72.88.12.8-1.62.6-0.42.0-0.6-1.31.8-0.70.2
One hour access (0.3 mA shock)0.50.61.11.0-0.51.1-0.71.0-0.6-1.00.9-0.6-0.1
Compulsive drug intake1.81.83.4-1.00.0-1.51.1-1.81.31.8-1.81.11.1
One hour access (shock baseline)1.51.73.31.4-0.21.6-1.11.8-1.3-1.41.8-0.9-0.4
Social response proportion0.10.10.3-0.40.4-0.10.40.1-0.10.5-0.10.3-0.3
Social responses0.10.20.40.10.20.20.50.6-0.6-0.20.30.60.0
Social time0.10.10.40.0-0.60.4-0.60.20.3-0.20.4-0.4-0.3
Soleus weight0.10.20.90.4-0.90.50.60.00.50.2-0.10.70.1
Bone: stiffness0.30.42.01.4-0.80.90.00.20.20.1-0.7-0.10.6
Tibialis anterior weight1.13.68.40.31.01.7-0.72.5-2.3-1.92.9-1.5-2.4
Time to tail flick, vehicle, before self-admin1.71.74.6-0.4-1.1-0.6-0.5-1.92.11.7-1.7-0.41.0
Time to tail flick, vehicle, after self-admin0.70.81.50.6-1.11.2-1.00.20.2-0.8-0.1-1.2-1.2
Time to tail flick, test, before self-admin0.30.30.7-0.90.8-0.7-0.6-0.2-0.30.40.3-0.40.2
Time to tail flick, test, after self-admin0.30.30.8-0.4-0.4-0.20.1-0.70.90.4-0.80.1-0.2
Delta time to tail flick, vehicle, before/after SA2.22.14.81.5-0.71.8-1.31.5-0.9-2.21.5-1.4-1.3
Delta time to tail flick, test, before/after SA0.10.10.5-0.0-0.10.00.3-0.30.20.0-0.70.2-0.3
Tibia length1.13.26.70.9-1.0-0.51.7-1.91.92.6-2.41.32.3
Ambulatory time before self-admin0.50.61.1-0.7-0.2-0.60.2-0.80.51.0-0.81.01.0
Ambulatory time after self-admin0.10.10.5-0.3-0.4-0.20.0-0.20.6-0.0-0.20.70.4
Bone: tissue strength1.31.32.7-0.70.8-1.11.4-1.00.11.6-1.61.30.7
Total heroin consumption0.20.20.70.3-0.90.0-0.2-0.30.6-0.2-0.30.10.7
Bone: trabecular number2.23.511.02.4-3.31.0-0.7-1.62.80.5-1.4-0.62.0
Bone: trabecular spacing1.72.16.5-1.32.5-0.4-0.11.6-2.6-0.81.5-0.1-1.1
Bone: trabecular thickness3.54.114.92.4-3.91.5-0.9-1.63.30.5-1.0-1.01.4
Bone: trabecular tissue density1.62.36.5-0.5-0.3-0.82.2-1.71.41.9-2.61.50.1
Water consumed over 24 hours0.30.41.10.8-0.50.20.5-0.30.50.8-0.30.31.0
Number of responses in last shaping day0.60.62.91.0-1.70.90.10.11.2-0.10.10.30.4