Ddx39b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA intron excision ratio chr20_3588267_3589585 0.2 0.12 6.3e-04 -0 -0 0.02 -0 7.0e-01 5.7e-01 2.0e-02 4.3e-01
2 PL gene expression Ddx39b 0.31 0.08 0.0e+00 0.33 0.42 0.42 0.42 2.5e-37 4.6e-49 5.8e-49 7.1e-49
3 IC gene expression Ddx39b 0.23 0.09 1.8e-09 0.22 0.21 0.23 0.25 9.5e-10 3.3e-09 3.0e-10 6.0e-11
4 BLA gene expression Ddx39b 0.33 0.1 0.0e+00 0.14 0.27 0.25 0.26 4.5e-08 1.1e-14 2.3e-13 6.8e-14
5 Adipose mRNA stability Ddx39b 0.19 0.09 0.0e+00 0.17 0.16 0.16 0.16 1.9e-18 1.0e-17 5.9e-17 1.2e-17
6 Brain gene expression Ddx39b 0.66 0.09 0.0e+00 0.55 0.65 0.68 0.68 9.4e-61 3.6e-80 4.9e-85 5.7e-86
7 LHb gene expression Ddx39b 0.45 0.15 6.9e-08 0.16 0.27 0.25 0.25 1.3e-04 3.4e-07 1.3e-06 1.1e-06
8 Brain intron excision ratio chr20_3588267_3589585 0.17 0.09 2.0e-05 0 0.02 0.01 0.01 2.7e-01 9.8e-03 1.6e-02 8.6e-02
9 Eye mRNA stability Ddx39b 0.69 0.14 1.4e-05 0.31 0.24 0.27 0.32 1.3e-05 1.4e-04 5.0e-05 8.6e-06
10 Liver gene expression Ddx39b 0.39 0.1 0.0e+00 0.32 0.32 0.33 0.33 4.7e-36 1.2e-35 7.9e-38 1.0e-37
11 NAcc intron excision ratio chr20_3588267_3589585 0.02 0.02 1.9e-03 0.01 0.01 0.01 0.01 6.1e-03 2.4e-03 4.2e-03 7.6e-03
12 IL gene expression Ddx39b 0.51 0.13 1.1e-10 0.4 0.37 0.4 0.35 1.2e-10 6.7e-10 8.5e-11 3.0e-09
13 IC mRNA stability Ddx39b 0.22 0.1 3.4e-07 0.18 0.18 0.14 0.17 4.5e-08 5.5e-08 1.6e-06 7.9e-08
14 NAcc gene expression Ddx39b 0.34 0.09 0.0e+00 0.39 0.43 0.42 0.43 2.1e-62 1.1e-70 2.5e-70 3.2e-71
15 pVTA gene expression Ddx39b 0.46 0.12 0.0e+00 0.37 0.42 0.41 0.42 2.4e-31 3.9e-36 1.3e-35 1.5e-36
16 pVTA alternative TSS XM_063278929.1 0.03 0.02 6.9e-03 0 0.01 0 -0 1.3e-01 7.5e-02 2.3e-01 4.0e-01
17 NAcc mRNA stability Ddx39b 0.18 0.07 0.0e+00 0.17 0.18 0.19 0.18 2.1e-24 5.3e-27 5.6e-28 7.8e-27
18 BLA mRNA stability Ddx39b 0.28 0.13 2.2e-06 0.07 0.1 0.07 0.07 8.7e-05 1.0e-05 1.6e-04 1.0e-04
19 RMTg gene expression Ddx39b 0.33 0.13 3.9e-07 0.24 0.25 0.18 0.27 5.0e-07 2.9e-07 1.3e-05 8.4e-08
20 pVTA mRNA stability Ddx39b 0.34 0.11 0.0e+00 0.18 0.22 0.23 0.24 4.1e-14 6.7e-18 9.0e-19 4.3e-19
21 Adipose gene expression Ddx39b 0.38 0.1 0.0e+00 0.52 0.5 0.51 0.51 1.8e-66 1.2e-63 1.2e-64 3.8e-66
22 Liver alternative TSS NM_133300.3 0.07 0.03 1.4e-10 0.1 0.08 0.09 0.09 5.6e-11 4.9e-09 1.8e-10 2.6e-10
23 Liver alternative TSS XM_063278929.1 0.07 0.03 1.9e-10 0.1 0.07 0.09 0.09 8.1e-11 1.1e-08 3.1e-10 5.2e-10
24 PL intron excision ratio chr20_3588267_3589585 0.03 0.02 1.9e-03 0 0.02 0.01 0.01 1.1e-01 2.5e-03 5.6e-02 5.5e-02
25 OFC gene expression Ddx39b 0.36 0.13 1.6e-07 0.3 0.24 0.18 0.28 6.2e-08 2.1e-06 5.1e-05 2.6e-07
26 Eye gene expression Ddx39b 0.49 0.15 1.4e-04 0.28 0.24 0.25 0.28 3.0e-05 1.3e-04 8.8e-05 3.8e-05
27 PL mRNA stability Ddx39b 0.2 0.1 1.2e-13 0.12 0.12 0.14 0.12 1.6e-13 1.5e-13 8.3e-15 5.1e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density0.30.63.50.3-0.7-0.4-0.8-0.8-0.1-0.4-0.21.9-0.2-0.7-0.2-1.80.10.10.9-1.51.10.40.5-0.60.6-0.60.9-0.50.4-0.4
Area under the delay curve0.10.10.80.00.20.20.30.90.10.20.2-0.40.20.6-0.40.70.20.1-0.50.5-0.30.2-0.20.0-0.00.0-0.00.10.4-0.0
BMI with tail1.55.28.72.6-2.4-2.5-2.32.9-2.5-2.3-1.91.52.5-2.82.3-1.3-2.5-2.5-1.4-2.42.0-2.81.62.6-2.62.6-2.72.40.3-1.2
BMI without tail1.57.812.82.7-2.6-3.1-2.53.6-3.1-2.7-2.60.93.3-2.53.1-0.7-3.2-3.1-3.2-2.12.2-3.32.33.2-3.23.2-3.33.31.6-1.9
Body weight1.46.323.10.9-1.5-2.7-1.54.8-2.2-1.9-1.0-0.43.1-1.92.41.1-2.8-2.8-2.3-1.11.5-3.61.13.5-3.53.5-4.23.4-0.30.2
Weight adjusted by age0.41.25.10.5-0.3-1.1-0.21.2-0.8-0.7-0.5-1.21.3-0.71.11.2-1.0-1.2-1.30.3-0.3-1.7-0.31.5-1.51.5-2.31.4-0.70.3
Bone surface0.10.10.4-0.60.40.40.30.00.40.40.6-0.5-0.50.3-0.40.50.40.20.50.3-0.20.2-0.5-0.20.2-0.2-0.0-0.0-0.60.5
Bone volume0.10.20.70.2-0.5-0.6-0.50.3-0.3-0.3-0.10.50.3-0.50.1-0.5-0.3-0.30.1-0.80.7-0.30.20.3-0.30.3-0.20.40.1-0.5
Breakpoint value in progressive ratio session0.20.30.6-0.60.60.40.6-0.80.50.60.4-0.1-0.70.7-0.40.30.60.50.30.3-0.50.8-0.4-0.60.6-0.60.8-0.70.2-0.1
Number of licking bursts1.03.05.8-1.71.82.41.9-1.21.91.91.7-2.1-1.91.8-1.71.61.91.71.42.3-2.01.6-1.8-1.41.4-1.41.2-1.6-1.31.4
Context. condit. distance diff. score6.27.612.4-2.92.92.72.8-3.53.02.92.9-1.6-3.22.4-3.01.72.92.93.32.0-2.72.7-2.8-2.82.8-2.82.6-2.9-2.81.7
Locomotion velocity, session 10.70.81.6-0.91.10.71.1-0.90.91.00.9-0.6-0.51.3-0.70.60.91.10.50.9-1.01.1-0.7-1.01.0-1.01.0-0.6-0.10.9
Locomotion distance, session 10.30.41.10.2-0.10.2-0.1-0.10.20.20.31.0-0.30.1-0.5-1.10.50.50.8-0.60.20.80.1-1.01.0-1.01.0-0.8-0.1-0.2
Locomotion velocity, session 20.70.81.4-0.91.00.71.0-0.21.01.11.1-0.7-0.61.2-1.10.51.01.20.80.7-0.81.2-0.9-1.01.0-1.01.1-0.7-0.40.1
Locomotion distance, session 20.81.12.9-0.70.70.70.7-0.51.00.91.20.3-0.80.7-1.2-0.41.11.21.70.0-0.51.2-0.9-1.61.6-1.61.3-1.4-1.21.2
Locomotion velocity, session 30.60.71.80.9-0.9-1.2-0.80.5-1.0-0.8-1.00.81.0-0.60.8-0.8-0.8-0.7-1.1-0.90.8-0.51.00.5-0.50.5-0.30.71.4-1.3
Locomotion distance, session 30.70.82.7-0.60.30.20.3-1.00.50.50.50.8-0.70.5-1.0-0.80.80.91.0-0.30.01.2-0.2-1.51.5-1.51.5-1.60.1-0.5
Stereotopy head waving bouts, day 30.50.63.0-0.80.90.70.90.60.50.70.7-1.5-0.00.9-0.21.70.40.3-0.21.4-1.00.0-0.6-0.30.3-0.3-0.5-0.1-0.51.0
Stereotopy head waving duration, day 30.30.41.80.00.30.20.30.7-0.20.0-0.2-1.10.60.30.71.3-0.3-0.4-1.11.1-0.6-0.50.10.3-0.30.3-0.90.60.40.7
Locomotion velocity, session 72.62.97.5-1.41.01.30.9-2.11.51.21.50.7-1.60.9-2.0-0.91.81.72.6-0.2-0.51.9-1.3-2.72.7-2.72.3-2.4-1.20.4
Locomotion distance, session 72.43.08.2-1.00.81.30.8-1.71.51.21.41.0-1.51.1-2.2-1.11.91.92.3-0.3-0.32.3-0.9-2.82.8-2.82.7-2.9-0.6-0.2
Stereotopy head waving bouts, day 70.30.32.9-0.10.10.20.11.7-0.2-0.0-0.1-0.40.80.70.20.5-0.1-0.0-1.20.40.30.10.70.1-0.10.1-0.10.41.2-0.4
Stereotopy head waving duration, day 70.30.43.00.0-0.1-0.1-0.11.7-0.4-0.2-0.2-0.30.80.30.50.5-0.4-0.3-1.20.20.4-0.30.80.4-0.40.4-0.50.71.0-0.3
Locomotion velocity, session 86.17.310.4-3.23.12.93.1-1.52.83.03.0-2.9-2.53.0-2.62.82.72.62.13.1-3.02.4-2.9-2.62.6-2.61.7-2.5-2.32.5
Locomotion distance, session 85.88.516.2-2.92.82.62.7-2.93.13.03.3-1.1-3.12.3-3.41.13.13.14.01.6-2.53.0-3.0-3.43.4-3.42.8-3.3-3.42.3
Degree of sensitization distance1.11.22.3-0.91.21.51.2-0.81.31.21.1-1.2-1.11.0-1.11.11.11.11.11.2-1.30.9-1.3-0.70.7-0.70.6-0.6-1.31.2
Degree of sensitization stereotypy0.20.21.5-0.10.10.30.01.2-0.00.10.0-0.00.30.7-0.1-0.00.20.3-0.70.10.40.50.6-0.10.1-0.10.40.11.1-0.6
Conditioned locomotion0.20.31.1-0.20.30.10.30.30.20.20.4-0.8-0.0-0.10.00.9-0.0-0.10.30.4-0.5-0.4-0.60.6-0.60.6-0.80.3-1.00.8
Cocaine response after cond. corrected0.60.93.5-0.50.60.80.6-0.81.10.91.1-0.3-1.40.2-1.30.10.90.91.90.2-0.80.7-1.3-1.01.0-1.00.6-1.1-1.70.8
Cocaine response after cond. not corrected0.60.92.1-0.91.00.81.0-0.31.01.11.1-1.4-1.10.7-1.01.30.80.81.01.0-1.20.4-1.3-0.40.4-0.40.1-0.4-1.41.0
Cocaine response before conditioning1.11.44.6-0.20.2-0.70.21.4-0.7-0.3-0.5-1.61.20.41.31.8-0.9-0.8-2.11.1-0.3-1.00.51.8-1.81.8-1.51.81.00.1
Saline control response5.88.111.62.8-2.8-3.3-2.81.9-3.1-3.1-3.21.83.3-2.63.3-1.5-3.1-3.0-3.4-2.22.7-2.83.13.0-3.03.0-2.63.03.0-2.1
Bone: connectivity density0.30.53.0-0.2-0.10.4-0.2-1.70.30.00.21.1-0.8-0.5-0.3-1.10.40.31.4-0.70.40.4-0.1-0.70.7-0.70.8-0.6-0.60.9
Bone: cortical apparent density1.72.64.01.9-1.9-1.9-1.91.1-1.8-1.8-1.71.61.6-2.01.6-1.5-1.8-1.7-1.2-1.81.7-1.61.71.4-1.41.4-1.31.41.1-1.3
Bone: cortical area0.10.22.4-0.40.2-0.20.21.5-0.00.30.4-0.40.10.3-0.20.50.00.0-0.10.1-0.1-0.0-0.0-0.20.2-0.2-0.30.1-0.3-0.6
Bone: cortical porosity0.40.42.90.40.1-0.20.20.9-0.4-0.1-0.5-0.40.90.90.20.3-0.1-0.0-1.70.4-0.00.30.50.2-0.20.20.20.41.7-1.2
Bone: cortical porosity0.30.41.7-0.30.60.50.70.60.20.40.1-1.10.41.3-0.10.90.30.3-1.21.0-0.50.6-0.1-0.10.1-0.10.40.11.1-0.5
Bone: cortical thickness1.52.68.61.8-1.9-2.0-1.82.9-1.7-1.5-1.31.81.9-1.41.1-1.6-1.4-1.3-1.2-2.02.0-1.01.90.8-0.80.8-0.91.01.4-2.1
Bone: cortical thickness2.73.34.92.2-2.2-2.0-2.21.9-2.1-2.0-1.92.11.7-2.01.8-1.9-1.8-1.8-1.5-2.22.1-1.52.21.1-1.11.1-1.21.51.4-1.4
Bone: cortical tissue density1.52.43.71.8-1.8-1.8-1.80.9-1.7-1.7-1.71.51.6-1.91.6-1.3-1.7-1.7-1.1-1.71.6-1.61.61.4-1.41.4-1.31.31.1-1.2
Condit. Reinf. active minus inactive responses0.20.21.2-0.20.40.40.3-1.10.20.30.10.3-0.30.7-0.3-0.40.60.6-0.1-0.0-0.20.80.1-0.40.4-0.41.1-0.50.50.4
Condit. Reinf. active-inactive response ratio0.50.51.20.8-0.7-0.5-0.70.3-0.9-0.7-0.90.50.7-0.40.8-0.7-0.5-0.6-1.1-0.70.7-0.41.00.7-0.70.7-0.20.61.1-0.1
Condit. Reinf. active responses0.20.31.9-0.20.2-0.00.1-1.40.10.10.00.9-0.20.3-0.2-0.90.50.50.3-0.40.10.70.1-0.50.5-0.51.1-0.50.40.5
Condit. Reinf. inactive responses0.50.63.2-0.1-0.3-0.5-0.4-1.40.2-0.10.01.8-0.2-0.3-0.4-1.60.30.41.0-1.00.70.70.3-0.90.9-0.91.2-0.80.5-0.1
Incentive salience index mean2.22.84.1-1.81.81.71.7-1.91.71.81.8-0.6-1.71.8-1.90.52.02.01.81.1-1.42.0-1.5-1.71.7-1.72.0-1.8-1.21.6
Condit. Reinf. lever presses4.87.112.2-3.02.72.52.6-2.73.02.83.1-1.3-3.02.3-3.01.32.92.93.51.9-2.42.6-2.9-2.72.7-2.72.4-2.8-2.72.4
Condit. Reinf. active minus inactive responses0.30.51.60.2-0.1-0.0-0.10.6-0.4-0.3-0.5-0.70.70.00.70.7-0.4-0.6-1.30.6-0.1-0.70.21.2-1.21.2-0.90.80.6-0.1
Condit. Reinf. active-inactive response ratio0.30.52.7-0.30.40.60.51.00.10.20.1-1.60.30.50.21.5-0.0-0.2-0.91.2-0.7-0.5-0.50.9-0.90.9-0.90.5-0.0-0.5
Condit. Reinf. active responses0.20.30.80.3-0.2-0.2-0.2-0.6-0.5-0.4-0.7-0.00.4-0.20.80.1-0.4-0.5-0.90.20.1-0.50.50.8-0.80.8-0.50.60.70.3
Condit. Reinf. inactive responses0.50.72.10.6-0.7-0.9-0.8-1.4-0.8-0.8-1.01.40.3-0.91.0-1.0-0.7-0.7-0.4-0.80.8-0.51.20.5-0.50.5-0.10.60.80.9
Condit. Reinf. lever presses0.10.11.40.10.10.30.0-1.2-0.1-0.1-0.40.20.10.20.4-0.30.10.0-0.40.10.00.20.40.2-0.20.20.40.30.70.6
Condit. Reinf. lever reinforcers received0.10.20.70.10.00.0-0.0-0.8-0.3-0.2-0.5-0.20.20.10.60.2-0.2-0.3-0.80.4-0.1-0.20.40.6-0.60.6-0.20.40.70.6
Conditioned reinforcement - actives0.10.42.00.3-0.7-0.6-0.71.4-0.6-0.7-0.40.40.8-0.5-0.3-0.8-0.6-0.6-0.6-0.80.9-0.60.20.2-0.20.2-0.50.40.4-1.0
Conditioned reinforcement - inactives0.20.61.50.8-0.8-0.7-0.71.2-0.8-0.9-0.70.31.0-0.50.1-0.6-0.7-0.8-1.0-0.70.7-0.70.30.8-0.80.8-0.60.80.9-1.1
Conditioned locomotion0.10.10.9-0.60.00.30.00.20.1-0.10.1-0.40.0-0.0-0.90.1-0.1-0.1-0.10.20.1-0.3-0.40.1-0.10.1-0.30.2-0.10.1
Patch foraging indifference point 0 sec1.85.17.32.6-2.3-2.7-2.21.2-2.4-2.5-2.71.72.5-2.22.7-1.3-2.5-2.4-2.5-1.51.8-2.32.22.6-2.62.6-2.02.52.2-0.8
Patch foraging indifference point AUC0.10.10.8-0.10.20.20.20.90.20.20.1-0.60.20.6-0.20.50.10.3-0.60.4-0.00.20.10.3-0.30.30.00.20.6-0.5
Delay disc. indifference point, 0s delay0.80.81.4-0.81.01.01.00.21.01.01.2-0.8-0.91.0-1.21.01.00.90.81.0-1.00.7-1.2-0.80.8-0.80.4-0.8-0.91.0
Delay disc. indifference point, 16s delay0.50.71.91.4-0.9-0.9-0.81.3-0.9-0.8-0.80.61.0-0.50.5-0.4-0.7-0.6-1.0-0.70.8-0.40.80.7-0.70.7-0.30.81.1-1.2
Delay disc. indifference point, 2s delay0.60.62.7-0.60.90.71.01.10.60.70.6-1.1-0.01.2-0.51.60.60.4-0.51.4-1.30.4-0.8-0.10.1-0.1-0.2-0.1-0.21.1
Delay disc. indifference point, 24s delay0.30.51.71.1-0.5-0.6-0.30.8-0.7-0.6-0.8-0.31.0-0.10.70.2-0.6-0.5-1.3-0.10.1-0.50.51.0-1.01.0-0.61.01.1-0.6
Delay disc. indifference point, 4s delay0.20.31.0-0.20.2-0.00.20.7-0.1-0.0-0.0-0.80.40.40.10.8-0.2-0.3-1.00.6-0.1-0.3-0.10.7-0.70.7-0.70.70.80.2
Delay disc. indifference point, 8s delay0.10.20.4-0.30.30.30.30.40.30.30.4-0.3-0.20.6-0.70.50.30.40.00.4-0.30.5-0.3-0.50.5-0.50.4-0.50.2-0.3
Indifference point function ln k0.41.11.7-1.11.21.01.2-0.71.11.21.1-0.8-1.01.3-1.11.01.21.10.71.3-1.21.2-0.9-1.11.1-1.11.0-1.0-0.61.0
Indifference point function log k0.41.11.7-1.11.21.01.2-0.71.11.21.1-0.8-1.01.3-1.11.01.21.10.71.3-1.21.2-0.9-1.11.1-1.11.0-1.0-0.61.0
Patch foraging total patch changes 0 sec1.95.67.82.8-2.4-2.8-2.31.5-2.5-2.6-2.81.72.7-2.32.7-1.4-2.6-2.5-2.6-1.61.9-2.42.32.7-2.72.7-2.12.62.4-0.9
Patch foraging total patch changes 12 sec2.33.15.22.3-1.9-1.9-1.81.5-1.8-1.9-2.11.22.0-1.62.0-1.1-1.9-1.7-2.1-1.21.5-1.61.91.8-1.81.8-1.51.92.0-0.8
Patch foraging total patch changes 18 sec2.15.07.32.6-2.7-2.3-2.71.0-2.3-2.5-2.52.52.1-2.72.3-2.4-2.3-2.2-1.6-2.42.6-2.12.51.9-1.91.9-1.41.92.0-1.8
Patch foraging total patch changes 24 sec0.82.86.42.3-2.1-1.9-2.00.6-1.6-1.9-1.92.51.5-1.91.5-2.3-1.5-1.3-1.0-2.22.0-1.11.91.1-1.11.1-0.41.21.8-1.9
Patch foraging total patch changes 6 sec2.94.98.42.9-2.4-2.6-2.21.4-2.3-2.4-2.61.82.6-2.22.5-1.6-2.4-2.1-2.3-1.81.8-2.12.22.5-2.52.5-1.82.32.1-0.8
Patch foraging time to switch 0 sec0.31.13.41.4-1.3-1.2-1.20.0-1.1-1.1-0.91.30.6-1.81.1-1.2-1.0-1.10.3-1.60.9-1.30.70.6-0.60.6-1.00.6-0.60.6
Patch foraging water rate 0 sec0.00.21.70.4-0.3-0.2-0.11.3-0.2-0.2-0.2-0.10.4-0.10.20.2-0.2-0.3-0.50.2-0.0-0.40.00.4-0.40.4-0.60.60.1-0.2
Patch foraging water rate 12 sec0.10.43.30.6-0.8-0.4-0.80.3-0.5-0.6-0.60.90.1-0.60.1-1.1-0.3-0.4-0.3-1.01.0-0.10.8-0.20.2-0.20.2-0.10.7-1.8
Patch foraging water rate 18 sec0.10.20.60.2-0.5-0.4-0.60.3-0.6-0.6-0.50.40.4-0.50.4-0.3-0.6-0.8-0.6-0.50.8-0.50.60.0-0.00.0-0.60.50.4-0.6
Patch foraging water rate 24 sec0.30.54.10.3-0.7-0.7-0.72.0-0.5-0.6-0.30.60.5-0.40.1-0.5-0.5-0.7-0.6-0.81.0-0.50.70.3-0.30.3-0.50.40.6-1.0
Patch foraging water rate 6 sec0.20.21.60.5-0.6-0.5-0.60.6-0.4-0.4-0.50.60.1-0.40.1-0.6-0.3-0.4-0.3-0.40.5-0.20.5-0.20.2-0.2-0.1-0.00.5-1.3
Seeking ratio, delayed vs. immediate footshock0.40.52.50.2-0.4-0.9-0.50.1-0.6-0.5-0.9-0.10.5-0.20.9-0.1-0.8-0.6-1.4-0.10.7-0.51.20.7-0.70.7-0.50.71.6-1.0
Distance traveled before self-admin0.10.31.8-1.30.50.90.3-0.30.50.40.8-0.6-0.4-0.0-0.90.40.20.20.90.4-0.2-0.1-0.70.2-0.20.2-0.30.1-0.50.4
Distance traveled after self-admin0.30.51.4-0.3-0.1-0.1-0.20.6-0.4-0.3-0.3-0.60.7-0.30.40.6-0.7-0.6-0.80.20.1-0.80.31.2-1.21.2-1.21.20.8-0.3
Extensor digitorum longus weight0.10.51.4-0.90.90.20.9-0.40.70.70.8-1.1-0.60.5-0.51.20.40.40.60.7-1.00.1-1.10.1-0.10.1-0.20.0-1.00.9
Bone: elastic displacement0.60.72.50.8-0.9-0.8-0.91.0-0.8-0.9-0.91.11.3-0.40.7-1.0-0.7-0.6-1.0-0.81.0-0.41.00.4-0.40.4-0.10.51.6-1.2
Bone: elastic work0.30.43.80.5-0.5-0.5-0.51.9-0.5-0.5-0.30.31.3-0.20.5-0.2-0.5-0.5-0.8-0.40.6-0.50.40.5-0.50.5-0.60.60.7-0.4
Bone: endosteal estimation1.22.914.0-2.01.91.41.90.11.01.31.3-3.7-0.91.4-0.23.70.50.2-0.32.9-2.2-0.5-1.90.5-0.50.5-1.40.7-1.92.2
Bone: endosteal perimeter1.94.610.8-2.92.72.42.6-1.52.12.32.2-3.3-2.22.1-1.53.31.61.51.43.0-2.81.0-2.5-1.01.0-1.00.2-1.0-2.52.0
Epididymis fat weight5.527.746.56.8-6.4-6.2-6.24.0-5.8-5.8-5.65.75.3-6.35.2-5.6-5.5-5.4-3.7-6.25.6-5.15.14.5-4.54.5-3.94.43.5-3.2
Delta time in closed arm before/after self-admin0.30.20.80.8-0.2-0.4-0.10.8-0.2-0.2-0.1-0.20.1-0.40.50.3-0.3-0.4-0.20.0-0.3-0.7-0.30.7-0.70.7-0.90.6-0.80.6
Delta time in open arm before/after self-admin0.40.51.9-0.4-0.5-0.3-0.70.3-0.8-0.8-0.60.80.9-0.5-0.0-0.7-0.7-0.7-0.8-0.61.1-0.60.80.6-0.60.6-0.30.71.4-0.7
Diff in mean of infusions in LGA sessions1.32.46.0-1.00.91.51.0-2.01.41.41.20.2-2.40.8-1.8-0.21.61.52.20.4-1.01.8-1.3-2.22.2-2.22.0-2.2-0.9-0.1
Delay discount exponential model param0.10.10.9-0.1-0.2-0.1-0.3-1.0-0.1-0.1-0.10.4-0.3-0.60.3-0.7-0.1-0.10.7-0.50.3-0.20.1-0.10.1-0.10.1-0.2-0.60.1
Extinction: sum of active levers before priming0.71.12.4-0.31.10.91.2-0.81.21.21.0-1.1-1.21.0-0.71.01.21.11.01.2-1.61.1-1.5-0.90.9-0.90.8-0.9-0.70.6
Active lever presses in extinction session 60.50.51.51.0-0.7-0.6-0.60.1-0.8-0.8-0.81.20.8-0.60.6-0.7-0.6-0.6-0.6-1.00.5-0.50.50.7-0.70.7-0.20.60.7-0.4
Bone: final force1.52.411.61.3-1.5-1.7-1.53.4-1.5-1.4-0.90.61.8-1.51.3-0.5-1.7-1.7-1.2-1.31.4-1.81.11.6-1.61.6-2.11.80.2-0.4
Bone: final moment1.42.210.01.2-1.4-1.7-1.43.2-1.5-1.4-0.90.61.8-1.41.3-0.4-1.6-1.7-1.3-1.31.4-1.81.01.6-1.61.6-2.01.70.4-0.5
Food consumed during 24 hour testing period0.20.41.9-0.90.6-0.10.60.50.50.60.9-0.8-0.30.2-0.51.10.10.20.80.5-0.6-0.2-0.9-0.10.1-0.1-0.6-0.2-1.40.8
Glucose5.48.514.2-3.13.52.73.6-2.62.93.23.1-3.4-2.83.2-2.73.52.62.72.23.6-3.82.3-3.4-2.42.4-2.41.6-2.3-2.82.6
Heart weight0.71.23.91.0-0.4-0.7-0.21.9-0.9-0.6-0.9-1.01.3-0.21.31.1-0.9-1.0-2.00.9-0.4-1.30.41.4-1.41.4-1.71.30.60.3
Delay discount hyperbolic model param0.10.21.1-0.1-0.2-0.1-0.3-1.0-0.1-0.2-0.10.5-0.3-0.70.2-0.8-0.1-0.10.8-0.60.4-0.20.1-0.20.2-0.20.1-0.2-0.7-0.0
Intermittent access intake day 1-15 change0.00.10.9-0.1-0.1-0.2-0.3-0.0-0.2-0.1-0.20.80.0-0.10.2-0.4-0.2-0.0-0.2-0.30.50.01.0-0.10.1-0.10.10.00.60.0
Intermittent access intake escalation0.20.93.40.4-0.8-1.0-1.00.3-1.0-0.9-1.01.50.8-0.60.8-1.2-0.9-0.7-1.0-1.11.4-0.51.90.5-0.50.5-0.10.61.5-0.8
Intermittent access intake escalation 20.10.10.6-0.80.40.10.2-0.40.20.30.30.3-0.10.50.1-0.10.20.3-0.10.10.20.40.5-0.20.2-0.20.5-0.20.5-0.0
Intermitt. access day 1 inactive lever presses0.22.14.0-1.11.61.61.70.41.61.71.7-1.9-1.51.4-1.21.81.41.21.31.5-1.91.0-1.9-1.21.2-1.20.3-1.1-2.01.4
Intermitt. access day 15 inactive lever presses0.00.21.80.4-0.1-0.4-0.11.4-0.3-0.2-0.0-0.00.6-0.10.60.3-0.4-0.5-0.5-0.20.0-0.60.00.7-0.70.7-0.90.6-0.1-0.4
Intermitt. access escalation Index0.92.74.9-1.81.41.91.4-1.81.81.71.5-0.1-2.11.3-2.20.31.81.82.10.9-1.31.8-1.3-1.91.9-1.91.9-2.0-0.90.9
Intermittent access day 1 total infusions0.10.21.2-0.1-0.1-0.2-0.1-0.2-0.0-0.1-0.00.80.20.1-1.1-0.70.20.20.2-0.60.30.4-0.3-0.50.5-0.50.7-0.50.3-1.1
Intermittent access day 15 total infusions0.30.72.40.2-0.8-0.9-0.90.2-0.8-0.9-0.81.60.8-0.5-0.1-1.2-0.6-0.6-0.8-1.21.3-0.21.10.2-0.20.20.20.21.2-1.4
Intermittent access terminal intake (last 3 days)0.40.71.90.6-0.8-1.0-0.80.6-0.9-0.9-1.01.01.0-0.50.2-0.7-0.7-0.7-1.2-0.91.0-0.51.00.6-0.60.6-0.20.61.2-1.4
Intermittent access total infusions0.40.52.5-0.0-0.7-0.7-0.70.2-0.7-0.8-0.70.90.8-0.4-0.4-0.8-0.5-0.5-0.8-0.91.0-0.30.60.3-0.30.3-0.00.31.0-1.6
Intermittent access day 1 locomotion0.10.20.7-0.4-0.5-0.1-0.6-0.6-0.4-0.6-0.30.80.1-0.6-0.5-0.8-0.4-0.50.0-0.80.8-0.50.30.1-0.10.1-0.10.2-0.1-0.7
Intermittent access day 15 total locomotion0.10.41.0-0.5-0.5-0.2-0.70.6-0.6-0.7-0.30.40.8-0.7-0.3-0.4-0.8-0.9-0.6-0.51.0-1.00.80.6-0.60.6-0.90.80.0-0.6
Intermittent access total locomotion0.50.62.1-0.5-0.7-0.5-1.00.4-0.8-1.0-0.60.60.9-0.7-0.2-0.8-0.9-1.0-0.7-0.91.4-1.00.80.6-0.60.6-0.70.70.6-1.2
Intermittent access standard deviation0.63.24.51.8-1.8-2.0-1.81.9-2.1-1.9-1.81.01.9-1.81.7-0.7-2.1-2.1-2.1-1.41.6-2.11.81.9-1.91.9-2.01.80.9-1.3
Left kidney weight1.18.620.61.9-2.3-3.2-2.44.5-3.0-2.6-2.10.53.5-2.53.10.1-3.4-3.4-3.1-1.92.3-3.82.03.8-3.83.8-4.23.81.0-1.1
Right kidney weight1.07.117.61.3-2.0-3.1-2.14.2-2.6-2.3-1.50.33.2-2.42.80.3-3.0-3.1-2.5-1.72.1-3.61.73.6-3.63.6-4.13.60.5-0.5
Cocaine induced anxiety0.30.92.5-1.31.01.30.9-1.11.10.90.9-0.5-1.60.6-1.30.70.80.91.10.8-0.90.7-1.0-0.80.8-0.80.5-0.7-1.01.1
Post-drug Anxiety0.10.10.6-0.20.30.30.3-0.60.20.2-0.0-0.6-0.60.00.10.50.10.10.10.8-0.6-0.1-0.50.1-0.10.1-0.20.1-0.00.6
Baseline Anxiety0.30.42.51.6-0.6-0.8-0.30.0-0.7-0.5-0.9-0.20.7-0.51.60.0-0.4-0.5-0.70.3-0.3-0.50.30.5-0.50.5-0.50.50.7-0.2
Tail length0.42.010.3-1.51.0-0.30.92.1-0.10.30.4-2.71.01.00.73.2-0.6-0.7-2.01.8-0.8-1.2-0.41.4-1.41.4-2.21.60.01.3
Length with tail0.72.912.7-2.01.1-0.70.92.8-0.00.30.9-2.91.30.70.73.6-0.8-0.9-1.61.8-0.8-1.7-0.91.9-1.91.9-2.92.0-0.91.9
Length without tail0.42.39.1-0.90.3-0.80.32.9-0.2-0.00.8-1.81.0-0.50.52.3-0.9-1.1-0.30.7-0.5-2.0-1.11.8-1.81.8-3.01.8-2.22.3
Times rat made contact with spout1.41.66.81.1-1.2-1.2-1.3-0.0-1.2-1.1-1.42.11.3-0.70.9-2.1-0.8-0.6-1.0-1.51.60.11.90.3-0.30.30.70.52.6-1.4
Lifetime Intake0.30.41.9-0.1-0.6-0.6-0.60.4-0.7-0.8-0.60.80.8-0.3-0.5-0.6-0.6-0.6-0.8-0.70.9-0.40.50.4-0.40.4-0.10.40.8-1.4
Liver weight, left1.01.76.5-1.81.60.81.6-0.51.01.31.4-2.2-1.21.0-0.72.60.60.60.71.5-1.7-0.1-1.60.2-0.20.2-0.70.1-2.22.2
Liver weight, right1.32.37.8-2.02.01.01.90.51.41.61.9-2.5-0.61.7-1.02.81.01.00.62.0-1.90.4-1.9-0.00.0-0.0-0.4-0.1-2.02.4
Locomotor activity0.30.52.4-1.50.70.30.6-0.20.10.20.2-1.40.20.70.31.5-0.2-0.2-0.91.2-0.3-0.2-0.20.6-0.60.6-0.60.80.50.7
Locomotor testing distance0.10.31.4-0.90.60.30.5-0.30.20.30.2-1.1-0.20.40.11.2-0.1-0.1-0.31.0-0.6-0.2-0.60.1-0.10.1-0.50.4-0.21.0
Locomotor testing rearing0.10.31.2-0.50.2-0.20.10.2-0.1-0.10.1-0.90.2-0.20.41.0-0.5-0.5-0.30.5-0.2-0.7-0.40.4-0.40.4-1.00.9-0.41.1
Locomotion in novel chamber0.10.10.7-0.0-0.2-0.2-0.20.8-0.1-0.2-0.00.30.1-0.10.0-0.3-0.2-0.1-0.2-0.20.5-0.20.50.2-0.20.2-0.20.20.5-0.6
Locomotion in novel chamber post-restriction0.41.32.50.9-1.1-1.3-1.11.4-1.2-1.2-1.20.41.5-1.31.50.0-1.3-1.4-1.2-0.40.8-1.60.91.1-1.11.1-1.61.20.7-0.6
Fecal boli incidents, locomotor time 10.10.20.50.2-0.4-0.6-0.4-0.7-0.4-0.5-0.50.60.5-0.70.7-0.7-0.4-0.5-0.0-0.20.2-0.6-0.10.3-0.30.3-0.40.30.40.2
Change in fecal boli incidents, locomotor task1.21.34.1-0.51.11.21.30.91.11.31.1-1.9-0.91.1-1.22.01.01.00.61.5-1.70.6-1.3-0.70.7-0.7-0.0-0.7-1.50.9
Time >=10cm from walls, locomotor time 10.50.62.8-0.50.50.20.60.70.30.40.5-1.1-0.3-0.10.01.5-0.1-0.30.40.8-1.0-0.6-1.00.6-0.60.6-1.20.6-1.71.2
Bouts of movement, locomotor time 10.50.61.6-1.00.70.80.5-1.30.80.80.8-0.2-0.50.7-0.8-0.20.91.00.90.3-0.21.1-0.2-1.01.0-1.01.1-0.9-0.30.7
Total resting periods, locomotor time 10.50.61.3-1.10.80.80.6-1.10.80.80.9-0.3-0.50.7-0.8-0.00.80.90.90.4-0.31.0-0.3-0.80.8-0.81.0-0.7-0.31.1
Rest time, locomotor task time 10.10.21.6-1.00.60.20.5-0.10.30.30.4-0.40.30.50.10.60.20.2-0.10.7-0.30.1-0.30.1-0.10.1-0.00.1-0.21.3
Distance moved, locomotor task time 10.10.20.80.8-0.5-0.3-0.40.9-0.4-0.3-0.30.20.4-0.40.10.0-0.4-0.4-0.3-0.40.3-0.40.40.5-0.50.5-0.50.50.2-0.9
Vertical activity count, locomotor time 10.10.62.00.7-0.9-0.6-0.90.8-0.7-0.8-0.70.70.4-0.90.6-0.5-0.8-0.9-0.5-0.80.8-0.90.90.6-0.60.6-0.80.60.2-1.4
Time >=10cm from walls, locomotor time 20.20.52.4-0.30.50.20.70.20.30.30.2-1.4-0.40.00.21.6-0.0-0.20.00.9-1.3-0.6-1.00.2-0.20.2-1.10.3-1.21.0
Bouts of movement, locomotor time 20.00.10.9-0.90.50.10.30.20.20.30.3-0.20.00.7-0.00.30.20.2-0.50.20.20.40.40.0-0.00.00.30.10.30.4
Total resting periods, locomotor time 20.10.41.9-1.41.00.50.8-0.10.60.70.7-0.5-0.21.2-0.40.70.60.7-0.30.8-0.20.80.1-0.20.2-0.20.6-0.10.20.8
Rest time, locomotor task time 21.52.56.2-2.51.91.71.7-1.21.81.72.0-1.4-1.21.4-1.41.31.51.51.81.6-1.41.2-1.5-1.21.2-1.20.8-1.1-1.92.0
Distance moved, locomotor task time 21.21.53.01.7-1.5-1.3-1.31.5-1.3-1.4-1.21.11.1-1.51.1-0.7-1.4-1.5-0.9-1.41.0-1.50.81.2-1.21.2-1.31.20.3-0.9
Vertical activity count, locomotor time 20.30.81.61.3-1.0-0.9-0.90.5-0.9-1.0-1.10.50.5-1.21.0-0.4-1.0-1.2-0.8-0.70.4-1.20.40.9-0.90.9-1.10.9-0.1-0.9
Light reinforcement 10.00.20.90.6-0.6-0.5-0.50.5-0.3-0.3-0.20.6-0.2-0.90.3-0.3-0.4-0.40.5-0.20.2-0.60.30.3-0.30.3-0.60.4-0.60.5
Light reinforcement 20.10.21.5-0.80.30.00.20.40.20.30.7-0.2-0.4-0.1-0.30.4-0.0-0.00.80.1-0.2-0.2-0.60.0-0.00.0-0.50.1-1.21.0
Bone: marrow area1.12.713.5-1.91.81.21.80.20.91.21.1-3.6-0.81.2-0.03.70.30.0-0.42.8-2.1-0.7-1.70.7-0.70.7-1.60.8-1.82.2
Bone: maximum diameter1.83.56.6-2.62.32.22.3-0.22.02.22.3-2.5-1.82.2-1.82.41.91.81.42.2-2.21.5-2.1-1.21.2-1.20.8-1.2-1.90.8
Bone: maximum force0.71.48.70.7-1.0-1.3-0.93.0-1.1-0.9-0.50.31.5-1.00.9-0.1-1.2-1.3-0.9-0.91.0-1.40.71.3-1.31.3-1.71.4-0.1-0.2
Bone: maximum moment0.61.27.20.6-0.9-1.3-0.82.7-1.0-0.8-0.40.21.4-0.90.90.0-1.2-1.2-0.9-0.80.9-1.40.51.2-1.21.2-1.61.3-0.1-0.3
Mean time between licks in bursts0.63.86.1-2.52.42.02.3-1.52.22.22.2-2.0-1.92.2-1.92.22.12.01.62.1-2.11.8-2.1-1.71.7-1.71.3-1.6-1.61.4
Mean num. licks in bursts1.84.98.82.1-2.3-3.0-2.41.1-2.4-2.4-2.32.92.5-2.12.2-2.5-2.3-2.0-1.9-2.92.7-1.52.71.5-1.51.5-0.91.82.6-2.0
Cd content in liver0.40.51.50.8-0.9-0.9-0.90.1-0.6-0.8-0.51.20.7-1.20.6-1.2-0.6-0.70.3-1.20.8-0.80.20.2-0.20.2-0.50.4-0.30.1
Co content in liver1.72.03.92.0-1.6-1.6-1.41.4-1.6-1.5-1.50.81.8-1.71.8-0.9-1.5-1.6-1.1-1.21.0-1.81.01.2-1.21.2-1.71.50.4-0.2
Cu content in liver0.81.04.21.1-1.1-0.8-1.1-0.7-0.8-0.8-1.12.10.5-0.70.3-2.0-0.4-0.3-0.4-1.41.30.31.3-0.20.2-0.20.9-0.21.7-1.0
Fe content in liver1.72.13.51.5-1.5-1.7-1.51.3-1.4-1.5-1.31.21.4-1.61.3-1.1-1.5-1.5-1.1-1.51.5-1.41.11.9-1.91.9-1.21.60.9-1.3
K content in liver0.40.41.00.00.30.40.40.10.60.70.70.2-0.60.5-0.8-0.10.70.91.00.1-0.31.0-0.3-0.70.7-0.70.9-0.8-0.5-0.0
Mg content in liver3.23.55.3-1.62.01.92.1-1.22.02.32.1-1.6-2.22.0-2.01.52.12.22.21.8-2.22.0-2.0-1.41.4-1.41.7-1.7-1.81.3
Mn content in liver4.95.58.2-2.52.62.32.6-2.32.42.62.5-2.4-2.72.1-2.22.32.22.22.42.6-2.91.7-2.8-1.91.9-1.91.3-1.9-2.72.7
Na content in liver0.20.21.00.5-0.40.0-0.41.0-0.1-0.1-0.20.6-0.20.1-0.4-0.70.10.2-0.3-0.30.60.50.7-0.20.2-0.20.5-0.30.8-0.6
Rb content in liver0.30.41.40.10.20.20.2-1.00.60.30.40.2-0.9-0.1-0.5-0.10.30.51.00.1-0.40.3-0.6-0.90.9-0.90.3-0.7-1.21.1
Se content in liver3.94.68.9-2.72.72.22.7-1.32.22.62.4-2.4-1.83.0-2.12.22.32.31.42.5-2.52.4-2.1-1.41.4-1.41.9-1.5-0.92.0
Sr content in liver0.20.21.1-0.20.10.20.10.2-0.0-0.10.1-0.80.3-0.00.40.6-0.1-0.3-0.20.5-0.2-0.7-0.30.6-0.60.6-0.70.5-0.51.0
Zn content in liver0.20.31.4-0.30.50.10.6-0.20.30.50.6-0.4-0.30.4-0.20.60.40.30.50.5-0.70.2-0.6-0.40.4-0.40.1-0.4-0.91.2
Bone: minimum diameter1.42.76.9-2.22.01.62.0-0.51.61.71.8-2.4-1.61.5-1.12.61.21.11.12.3-2.10.6-1.9-1.11.1-1.1-0.1-0.8-2.12.0
Time in familiar zone, hab. session 11.61.86.81.2-1.4-1.0-1.5-0.6-1.2-1.4-1.52.60.9-1.11.0-2.5-0.8-0.8-0.7-1.81.8-0.12.0-0.20.2-0.20.7-0.22.1-1.6
Time in novel zone, hab. session 10.80.94.4-0.71.00.51.00.30.60.80.8-2.1-0.50.6-0.22.10.20.20.01.4-1.4-0.3-1.20.5-0.50.5-0.90.5-1.51.3
Total zone transitions, hab. session 10.40.51.4-0.20.50.60.5-1.00.70.70.50.2-0.90.5-0.6-0.00.70.80.90.2-0.60.9-0.1-1.21.2-1.20.9-1.0-0.70.3
Total locomotion distance, hab. session 10.40.62.0-0.20.30.60.4-0.70.60.60.50.4-0.80.3-0.7-0.20.60.71.00.1-0.40.8-0.1-1.41.4-1.40.8-1.2-0.90.2
Locomotion velocity, hab. session 10.20.31.30.10.20.40.3-0.30.40.50.40.3-0.60.3-0.5-0.10.50.60.60.1-0.40.7-0.0-1.11.1-1.10.6-0.9-0.70.0
Time in familiar zone, hab. session 20.70.82.30.8-1.0-1.0-1.10.1-1.0-0.9-1.11.30.7-1.00.9-1.2-0.9-0.8-0.6-1.11.2-0.51.50.6-0.60.6-0.10.61.0-0.4
Time in novel zone, hab. session 20.10.10.30.10.1-0.00.20.2-0.0-0.1-0.0-0.50.20.10.10.5-0.1-0.2-0.40.3-0.3-0.3-0.40.2-0.20.2-0.40.3-0.0-0.3
Total zone transitions, hab. session 20.20.31.2-0.00.00.70.0-0.00.50.40.40.2-0.8-0.1-0.5-0.30.40.40.90.1-0.20.3-0.2-0.90.9-0.90.3-0.7-0.81.1
Total locomotion distance, hab. session 20.91.13.2-0.40.31.10.3-0.91.00.80.80.6-1.40.1-1.1-0.51.01.01.80.1-0.41.0-0.5-1.71.7-1.71.1-1.6-1.41.4
Locomotion velocity, hab. session 21.41.94.3-0.70.71.50.7-1.01.41.21.20.3-1.70.6-1.5-0.31.41.42.10.4-0.71.4-0.8-2.12.1-2.11.4-2.0-1.61.6
Novel to familiar place preference ratio0.00.10.30.30.00.20.10.20.30.10.1-0.00.10.3-0.4-0.10.30.4-0.10.2-0.10.5-0.1-0.00.0-0.00.4-0.30.2-0.6
Novelty place preference0.10.10.30.30.10.30.20.40.30.20.1-0.20.20.4-0.30.10.30.3-0.20.3-0.20.4-0.10.0-0.00.00.3-0.20.3-0.5
Time in novel zone, NPP test0.10.10.20.30.10.30.10.50.20.1-0.0-0.30.20.4-0.20.20.20.2-0.40.4-0.10.3-0.00.2-0.20.20.2-0.00.4-0.5
Total zone transitions, NPP test0.91.32.9-0.70.71.10.7-1.31.10.91.00.3-1.40.6-1.2-0.31.11.11.70.2-0.61.2-0.8-1.71.7-1.71.3-1.6-1.31.3
Total locomotion distance, NPP test0.60.93.2-0.10.20.60.3-0.90.80.60.80.7-1.00.0-1.0-0.70.80.81.8-0.3-0.30.8-0.7-1.51.5-1.50.9-1.5-1.60.8
Locomotion velocity, NPP test1.01.55.0-0.30.40.70.4-1.21.00.81.10.8-1.30.1-1.3-0.81.11.12.2-0.2-0.51.1-0.9-1.81.8-1.81.3-1.9-1.70.9
Intraocular pressure0.30.62.10.2-0.8-0.6-1.0-0.9-0.5-0.9-0.71.50.1-1.10.3-1.3-0.6-0.60.1-1.31.3-0.50.80.2-0.20.2-0.00.00.4-0.9
Delta distance traveled before/after self-admin1.01.14.71.1-0.6-1.0-0.51.5-1.1-0.9-1.2-0.21.4-0.21.20.3-1.1-1.0-2.2-0.10.4-0.91.01.2-1.21.2-1.11.31.5-1.0
Delta ambulatory time before/after self-admin0.30.52.70.6-0.2-0.5-0.21.3-0.6-0.4-0.7-0.50.90.10.90.5-0.6-0.6-1.60.20.0-0.50.70.8-0.80.8-0.80.91.0-0.6
Parametrial fat weight1.22.95.71.0-1.9-1.9-2.11.9-1.8-1.9-1.11.51.6-2.41.5-1.3-2.1-2.2-0.6-2.22.4-2.31.21.3-1.31.3-2.11.6-0.2-0.8
Pavlov. Cond. lever latency6.07.610.83.3-3.1-2.7-3.01.8-3.2-3.1-3.22.22.6-3.33.2-1.9-3.2-3.2-2.5-2.52.6-3.02.92.9-2.92.9-2.72.61.7-1.2
Pavlov. Cond. magazine entry latency2.93.76.6-2.52.32.22.2-2.12.12.11.8-1.5-2.02.6-2.01.52.22.21.22.0-1.82.3-1.6-1.61.6-1.62.2-1.8-0.30.5
Pavlov. Cond. change in total contacts1.81.94.1-2.01.71.51.6-0.21.51.61.6-1.5-1.12.0-1.61.31.51.50.71.5-1.21.6-1.3-1.21.2-1.21.3-1.2-0.20.3
Pavlov. Cond. index score5.77.211.1-3.33.12.83.0-2.33.13.02.9-2.1-2.83.3-3.02.03.03.12.32.6-2.53.0-2.6-2.62.6-2.62.7-2.6-1.41.1
Pavlov. Cond. latency score6.17.811.7-3.43.22.93.1-2.03.23.13.1-2.3-2.83.4-3.22.13.23.22.42.7-2.63.2-2.7-2.72.7-2.72.8-2.7-1.51.1
Pavlov. Cond. lever contacts6.27.410.6-3.33.02.73.0-1.63.23.03.2-2.2-2.73.0-3.12.03.03.12.72.5-2.62.7-3.0-2.82.8-2.82.3-2.5-2.21.5
Pavlov. Cond. magazine entry number1.92.55.12.0-1.9-1.8-1.82.3-1.7-1.7-1.41.21.7-2.01.5-1.2-1.8-1.8-1.0-1.71.6-1.91.31.2-1.21.2-1.81.40.3-0.8
Pavlov. Cond. intertrial magazine entries1.92.34.71.8-1.8-2.2-1.80.1-1.7-1.7-1.62.11.4-2.01.4-2.1-1.5-1.6-0.7-2.11.7-1.31.30.9-0.90.9-0.80.91.1-1.1
Pavlov. Cond. lever-magazine prob. diff.5.56.810.4-3.23.02.72.9-2.42.92.92.8-1.9-2.73.1-3.01.93.03.02.22.5-2.43.0-2.5-2.62.6-2.62.7-2.5-1.31.0
Pavlov. Cond. response bias3.94.98.0-2.82.62.32.5-2.42.52.42.3-1.6-2.32.6-2.41.62.52.51.92.2-2.12.4-2.1-2.12.1-2.12.3-2.1-1.11.0
Pavlov. Cond. lever latency0.40.61.4-0.80.80.40.80.60.80.91.1-1.0-0.90.6-0.91.10.60.60.90.8-0.90.3-1.0-0.60.6-0.6-0.0-0.9-1.20.2
Pavlov. Cond. magazine entry latency0.20.20.8-0.50.50.90.50.10.60.50.6-0.6-0.20.7-0.50.30.60.50.30.4-0.30.4-0.6-0.50.5-0.50.3-0.4-0.40.5
Pavlov. Cond. change in total contacts0.10.41.40.7-0.50.1-0.60.3-0.6-0.7-0.80.10.7-0.20.6-0.5-0.4-0.6-1.2-0.30.6-0.40.70.5-0.50.5-0.30.71.0-0.5
Pavlov. Cond. index score0.00.10.30.1-0.00.3-0.1-0.4-0.1-0.2-0.20.00.30.20.2-0.20.0-0.1-0.5-0.00.20.10.20.0-0.00.00.10.30.50.2
Pavlov. Cond. latency score0.10.10.50.4-0.20.1-0.3-0.1-0.3-0.4-0.40.10.6-0.00.5-0.3-0.2-0.3-0.7-0.20.4-0.20.40.2-0.20.2-0.10.50.60.2
Pavlov. Cond. lever contacts0.40.61.10.8-0.7-0.3-0.8-0.4-0.8-0.8-1.00.80.8-0.50.8-1.0-0.6-0.7-0.9-0.80.9-0.40.90.7-0.70.7-0.11.01.0-0.4
Pavlov. Cond. magazine entry number0.00.00.20.2-0.0-0.5-0.0-0.2-0.2-0.0-0.20.2-0.1-0.10.20.1-0.2-0.0-0.10.1-0.2-0.10.30.3-0.30.3-0.00.10.2-0.3
Pavlov. Cond. intertrial magazine entries0.71.53.7-1.51.51.01.4-1.91.31.51.2-0.9-1.41.4-1.11.11.41.51.01.4-1.31.4-0.8-0.60.6-0.61.3-1.0-0.51.3
Pavlov. Cond. lever-magazine prob. diff.0.00.10.20.1-0.10.3-0.1-0.5-0.1-0.2-0.30.10.40.10.3-0.3-0.0-0.1-0.5-0.10.30.00.30.0-0.00.00.10.30.50.3
Pavlov. Cond. response bias0.10.10.5-0.10.10.6-0.0-0.70.1-0.1-0.10.20.00.2-0.1-0.40.20.1-0.1-0.20.30.30.1-0.10.1-0.10.50.20.40.0
Time in closed arm before self-admin0.10.10.40.30.30.30.4-0.30.20.30.1-0.5-0.20.2-0.10.60.10.1-0.00.6-0.70.1-0.5-0.20.2-0.2-0.1-0.1-0.30.5
Time in closed arm after self-admin0.10.21.61.1-0.3-0.4-0.11.3-0.2-0.1-0.10.20.2-0.20.20.0-0.2-0.3-0.20.0-0.2-0.2-0.30.2-0.20.2-0.40.2-0.30.4
Time in open arm before self-admin0.40.51.1-1.00.80.60.7-1.00.70.60.5-0.4-0.61.0-0.60.30.70.80.20.5-0.40.9-0.2-0.70.7-0.71.0-0.70.1-0.8
Time in open arm after self-admin0.20.21.5-1.00.20.4-0.0-0.8-0.2-0.3-0.3-0.20.20.2-0.40.0-0.2-0.1-0.70.00.3-0.10.30.3-0.30.30.10.41.1-1.2
Bone: periosteal estimation0.51.26.6-1.31.10.61.11.00.40.70.8-2.4-0.30.80.02.60.1-0.1-0.51.8-1.3-0.6-0.90.4-0.40.4-1.30.7-1.10.9
Bone: periosteal perimeter0.81.54.3-1.81.61.31.50.11.11.41.4-2.1-1.01.4-0.92.10.90.90.51.8-1.50.6-1.4-0.80.8-0.80.0-0.6-1.30.7
Bone: post-yield work0.91.54.4-1.71.51.11.4-1.31.11.21.3-1.7-1.40.9-0.81.90.80.71.11.5-1.60.3-1.5-0.50.5-0.5-0.1-0.5-2.11.5
Progressive ratio test 1 active lever presses0.00.10.20.3-0.3-0.2-0.20.3-0.3-0.3-0.30.30.1-0.2-0.5-0.1-0.2-0.2-0.3-0.40.0-0.2-0.1-0.00.0-0.0-0.20.1-0.1-0.2
Progressive ratio test 1 breakpoint0.00.00.20.4-0.3-0.2-0.20.3-0.3-0.3-0.20.30.1-0.1-0.4-0.0-0.2-0.2-0.3-0.3-0.0-0.2-0.1-0.00.0-0.0-0.20.2-0.2-0.2
Progressive ratio test 1 inactive lever presses0.20.62.11.4-1.1-0.7-1.00.6-0.8-0.8-0.70.90.4-1.10.3-1.2-0.7-0.8-0.1-1.30.8-0.70.40.0-0.00.0-0.40.3-0.0-0.7
Progressive ratio test 2 active lever presses0.10.20.90.1-0.3-0.1-0.3-0.3-0.2-0.2-0.20.8-0.1-0.1-0.6-0.90.00.10.1-0.70.50.30.3-0.40.4-0.40.6-0.40.3-1.0
Progressive ratio test 2 breakpoint0.20.21.30.1-0.4-0.2-0.5-0.2-0.3-0.3-0.30.9-0.0-0.2-0.6-1.0-0.10.0-0.0-0.80.70.20.4-0.40.4-0.40.6-0.40.4-1.1
Progressive ratio test 2 inactive lever presses0.10.31.2-0.70.60.50.60.40.50.50.7-0.2-0.20.7-1.10.40.60.50.40.3-0.60.4-0.9-0.60.6-0.60.3-0.5-0.5-0.3
Incentive Sensitization - Responses0.10.31.2-0.40.20.40.2-0.80.30.30.10.4-0.40.5-0.5-0.60.50.60.3-0.00.10.80.1-0.60.6-0.61.1-0.90.4-0.6
Incentive Sensitization - Breakpoint0.10.31.1-0.30.10.30.0-0.80.20.20.10.6-0.30.3-0.5-0.70.40.50.4-0.20.30.70.3-0.60.6-0.61.1-0.90.4-0.8
Sum of active levers in priming session hrs 5-60.10.10.5-0.00.40.10.5-0.70.20.20.0-0.20.30.50.40.70.30.2-0.20.7-0.60.3-0.20.1-0.10.10.20.10.30.5
Progressive ratio1.64.68.31.6-2.0-2.2-2.12.9-2.2-2.1-2.00.82.4-2.02.2-0.6-2.4-2.4-2.5-1.12.0-2.62.22.6-2.62.6-2.72.61.4-0.2
Food seeking constrained by brief footshock0.30.41.30.2-0.5-0.5-0.6-0.1-0.5-0.7-0.70.30.6-0.40.3-0.7-0.6-0.4-0.8-0.40.7-0.40.50.9-0.90.9-0.20.91.1-0.4
Seeking ratio, punishment vs. effort1.32.85.9-1.11.61.81.7-2.41.81.71.4-0.9-1.91.8-1.80.51.91.91.61.1-1.72.1-1.8-1.81.8-1.82.2-1.8-0.80.0
Retroperitoneal fat weight0.10.61.80.2-0.8-1.0-0.91.3-0.7-0.7-0.11.01.1-0.90.4-0.8-0.8-0.80.1-1.21.2-0.90.30.4-0.40.4-0.70.3-0.30.1
Reaction time number correct1.03.55.22.3-2.1-2.0-2.01.4-2.2-2.1-2.21.41.5-2.12.1-1.3-2.1-2.2-1.8-1.61.7-2.01.81.8-1.81.8-1.81.61.3-2.0
Reaction time mean minus median0.63.712.3-3.52.31.61.9-1.82.12.02.4-1.0-1.72.1-2.41.31.92.02.01.0-1.02.0-1.7-2.02.0-2.01.8-1.9-1.31.0
Reaction time mean minus median AUC0.53.18.8-3.02.01.51.8-1.62.01.82.3-0.9-1.51.9-2.20.91.91.92.00.7-1.01.9-1.8-1.81.8-1.81.8-1.8-1.30.8
Reaction time num false alarms0.50.81.5-0.81.01.21.00.41.01.11.0-1.0-0.81.2-1.01.01.01.00.51.2-0.91.1-0.6-0.70.7-0.70.7-0.7-0.20.5
Reaction time num false alarms AUC0.40.92.2-0.81.01.31.10.61.01.21.0-1.3-0.81.4-0.91.21.01.00.31.5-1.11.1-0.6-0.60.6-0.60.7-0.6-0.00.4
Reaction time trials correct on left1.03.55.22.3-2.1-2.0-2.01.4-2.2-2.1-2.21.41.5-2.12.1-1.3-2.1-2.2-1.8-1.61.7-2.01.81.8-1.81.8-1.81.61.3-2.0
Reaction time trials on left1.03.34.92.2-2.0-1.9-2.01.4-2.1-2.1-2.11.31.5-2.12.1-1.2-2.0-2.1-1.8-1.51.6-2.01.81.8-1.81.8-1.81.61.2-1.9
Reaction time mean2.55.610.7-3.32.62.52.4-2.22.62.52.9-1.9-2.32.2-2.71.62.42.22.81.6-1.92.1-2.8-2.32.3-2.31.7-2.2-2.62.3
Reaction time mean AUC2.15.210.8-3.32.52.32.3-2.22.52.32.8-1.7-2.12.1-2.61.52.32.12.71.5-1.82.0-2.7-2.22.2-2.21.7-2.0-2.42.2
Median of all reaction times2.64.16.9-2.52.12.22.0-1.92.22.02.4-1.8-2.01.7-2.11.42.01.82.41.5-1.81.5-2.6-1.91.9-1.91.2-1.8-2.52.4
Reaction time omissions2.03.37.9-2.82.01.91.9-1.52.01.92.3-1.5-1.71.7-2.11.51.71.72.11.3-1.41.6-2.1-1.81.8-1.81.3-1.7-1.71.5
Reaction time false alarm rate2.73.76.6-2.02.22.32.2-0.32.22.32.1-2.1-1.62.6-2.11.92.12.21.22.3-2.02.2-1.6-1.61.6-1.61.6-1.5-0.81.6
Reaction time premature initiation rate0.20.43.00.5-0.4-0.5-0.31.7-0.4-0.4-0.2-0.30.7-0.50.60.2-0.5-0.7-0.50.10.1-0.9-0.10.6-0.60.6-1.10.8-0.30.3
Reaction time premature initiations0.82.45.91.8-1.6-1.6-1.42.4-1.6-1.6-1.40.41.6-1.71.8-0.5-1.7-1.9-1.5-0.81.0-2.11.01.7-1.71.7-2.11.70.5-0.9
Std. dev. reaction times1.55.113.0-3.62.72.32.5-1.82.52.52.8-1.9-1.82.6-2.61.92.32.32.11.7-1.72.3-2.3-2.22.2-2.21.9-2.0-1.61.4
Reaction time trials completed1.03.34.92.2-2.0-1.9-2.01.4-2.1-2.1-2.11.31.5-2.12.1-1.2-2.0-2.1-1.8-1.51.6-2.01.81.8-1.81.8-1.81.61.2-1.9
Reaction time trials AUC0.93.24.72.2-2.0-1.9-1.91.3-2.1-2.0-2.11.31.4-2.12.0-1.3-2.0-2.1-1.7-1.51.6-2.01.71.7-1.71.7-1.71.51.1-1.9
Run reversals in cocaine runway, females0.60.71.41.2-1.0-0.7-1.00.4-1.0-1.1-1.00.91.0-1.10.8-0.7-0.9-0.9-0.6-0.90.9-0.80.80.5-0.50.5-0.60.50.2-0.3
Run reversals in cocaine runway, males0.91.05.1-2.31.21.01.00.21.11.11.5-0.8-0.41.2-1.20.61.00.90.90.8-0.40.8-0.8-0.90.9-0.90.6-0.9-0.60.0
Latency to leave start box in cocaine runway1.31.83.0-0.61.21.11.40.41.51.51.5-0.8-1.41.3-1.30.81.61.41.51.0-1.61.5-1.7-1.61.6-1.61.0-1.7-1.60.6
Latency to leave start box in cocaine runway, F1.01.32.2-0.61.01.01.1-0.11.31.21.2-0.6-1.31.0-1.10.41.31.21.30.8-1.21.3-1.5-1.41.4-1.41.0-1.4-1.40.2
Latency to leave start box in cocaine runway, M0.40.41.3-0.00.50.20.61.10.60.70.8-0.3-0.20.6-0.40.70.60.60.60.3-0.70.5-0.7-0.60.6-0.60.1-0.7-0.80.6
Std. dev. time between licks in bursts2.34.39.4-2.22.52.32.6-1.12.32.32.2-3.1-1.82.3-1.72.82.11.91.42.9-2.71.5-2.6-0.70.7-0.70.8-1.0-1.82.2
Total sessions with >9 infusions0.20.30.9-0.1-0.5-0.4-0.50.5-0.6-0.6-0.60.50.9-0.1-0.4-0.2-0.5-0.5-1.0-0.40.6-0.30.60.5-0.50.5-0.20.50.9-0.9
Short access day 1 total inactive lever presses0.30.72.2-1.50.90.80.91.00.80.71.1-1.1-0.01.1-1.20.90.70.50.20.9-0.60.4-1.5-0.50.5-0.5-0.0-0.3-0.6-0.3
Short access day 10 total inactive lever presses0.10.81.9-0.70.71.00.7-0.41.01.01.10.2-1.20.6-1.3-0.11.00.91.40.2-0.61.0-0.7-1.21.2-1.20.9-1.3-0.9-0.3
Short access day 1 total infusions0.00.10.7-0.20.10.10.2-0.20.0-0.0-0.00.40.20.3-0.80.10.10.0-0.20.1-0.30.2-0.1-0.10.1-0.10.2-0.1-0.00.6
Short access day 10 total infusions0.20.31.00.1-0.6-0.5-0.60.2-0.5-0.6-0.40.70.6-0.3-0.5-0.7-0.4-0.3-0.4-0.80.9-0.20.40.1-0.10.10.10.20.6-1.0
Short access total infusions0.10.20.5-0.1-0.4-0.4-0.30.5-0.4-0.5-0.30.70.6-0.1-0.7-0.3-0.3-0.4-0.6-0.50.5-0.20.10.2-0.20.2-0.10.20.5-0.6
Short access day 1 locomotion0.61.03.2-0.80.70.90.7-1.61.00.90.8-0.2-1.30.7-1.80.11.01.21.20.4-0.71.2-0.7-1.31.3-1.31.3-1.2-0.50.2
Short access day 10 total locomotion0.10.52.9-0.40.50.60.6-0.10.20.30.1-1.7-0.30.2-0.41.7-0.1-0.1-0.51.2-1.0-0.5-0.50.7-0.70.7-1.00.6-0.40.9
Short access total locomotion0.20.31.3-0.60.50.80.5-0.50.40.40.4-1.0-0.70.3-1.11.00.20.20.20.8-0.8-0.0-0.7-0.10.1-0.1-0.2-0.0-0.80.8
One hour access (0.3 mA shock)1.21.44.1-0.90.70.70.6-1.21.01.00.90.5-1.40.8-1.4-0.41.31.31.40.1-0.21.6-0.3-2.02.0-2.01.8-1.9-0.50.1
Compulsive drug intake4.26.210.0-2.02.32.52.4-2.22.72.82.5-1.5-3.11.9-2.31.42.72.73.22.3-2.62.5-2.1-3.03.0-3.02.1-2.9-2.52.4
One hour access (shock baseline)0.61.64.40.4-1.3-1.5-1.40.8-1.3-1.5-1.11.71.5-0.90.8-1.6-1.1-1.2-1.2-1.82.1-0.81.40.7-0.70.7-0.20.71.5-2.0
Social response proportion0.30.41.8-0.20.50.10.6-0.10.10.20.0-1.40.00.30.21.2-0.0-0.1-0.41.1-1.1-0.3-1.00.6-0.60.6-0.80.4-0.61.3
Social responses0.20.31.30.10.30.00.40.5-0.10.1-0.2-1.10.20.30.30.9-0.1-0.2-0.81.0-0.8-0.2-0.60.6-0.60.6-0.60.50.10.5
Social time3.35.310.2-3.22.62.62.5-0.92.72.62.8-2.3-2.22.4-2.62.22.52.42.32.4-2.12.2-2.5-2.02.0-2.01.5-2.0-2.11.5
Soleus weight2.98.620.1-3.23.53.53.6-0.93.13.33.3-4.5-2.92.9-2.34.42.52.42.24.0-3.91.5-3.7-1.01.0-1.00.5-1.3-3.73.0
Bone: stiffness0.40.82.00.8-1.1-1.2-1.11.4-1.0-0.9-0.70.90.8-1.20.7-0.6-1.0-1.0-0.4-1.21.1-1.00.90.6-0.60.6-1.00.80.0-0.7
Tibialis anterior weight0.41.52.81.5-1.5-1.7-1.41.0-1.3-1.2-1.31.51.3-1.31.0-1.4-1.1-1.1-0.9-1.51.3-0.91.21.0-1.01.0-0.71.01.3-0.3
Time to tail flick, vehicle, before self-admin0.50.62.6-1.10.50.60.3-1.00.80.81.00.4-0.60.3-0.9-0.40.80.91.6-0.00.11.0-0.2-0.90.9-0.91.2-1.0-0.2-0.3
Time to tail flick, vehicle, after self-admin0.51.12.1-1.51.11.21.1-1.01.11.11.1-0.6-0.91.1-1.30.71.11.11.01.0-0.91.2-0.9-1.21.2-1.21.0-1.2-0.00.8
Time to tail flick, test, before self-admin0.10.20.6-0.2-0.2-0.3-0.4-0.1-0.2-0.2-0.30.7-0.1-0.1-0.0-0.7-0.2-0.1-0.2-0.50.80.20.7-0.30.3-0.30.5-0.30.3-0.7
Time to tail flick, test, after self-admin0.50.52.1-1.00.40.10.2-0.90.50.30.50.90.10.7-0.2-1.00.60.70.5-0.50.61.00.1-0.70.7-0.71.4-0.71.0-0.8
Delta time to tail flick, vehicle, before/after SA0.10.10.20.0-0.10.1-0.00.1-0.1-0.2-0.20.50.10.2-0.3-0.40.10.0-0.3-0.30.10.20.0-0.30.3-0.30.4-0.30.40.0
Delta time to tail flick, test, before/after SA0.10.10.50.4-0.2-0.2-0.2-0.4-0.0-0.10.00.70.3-0.30.3-0.70.10.10.6-0.60.30.1-0.1-0.10.1-0.10.4-0.10.3-0.1
Tibia length0.51.58.0-1.31.0-0.11.11.10.20.70.9-2.4-0.00.50.22.8-0.3-0.4-0.31.7-1.4-1.2-1.20.6-0.60.6-1.90.8-1.71.9
Ambulatory time before self-admin0.00.11.1-1.00.30.60.1-0.10.30.20.50.0-0.10.1-0.8-0.10.20.20.50.10.10.1-0.30.1-0.10.10.00.00.1-0.1
Ambulatory time after self-admin0.30.51.3-0.3-0.0-0.0-0.11.0-0.4-0.3-0.3-0.21.0-0.10.40.4-0.6-0.6-1.00.30.1-0.70.41.1-1.11.1-1.01.11.1-0.1
Bone: tissue strength0.50.64.40.3-0.5-0.9-0.42.1-0.5-0.40.10.11.3-0.40.2-0.1-0.6-0.6-0.3-0.70.5-0.7-0.01.1-1.11.1-0.90.6-0.1-0.1
Total heroin consumption0.10.10.3-0.60.50.30.5-0.10.30.40.4-0.2-0.20.5-0.20.30.40.30.20.2-0.30.4-0.0-0.20.2-0.20.2-0.20.1-0.0
Bone: trabecular number0.50.95.00.3-0.8-0.2-0.9-0.7-0.1-0.5-0.22.2-0.1-0.8-0.3-2.20.10.11.1-1.71.40.50.7-1.01.0-1.01.1-0.80.4-0.5
Bone: trabecular spacing0.60.94.3-0.30.5-0.20.61.6-0.10.20.2-2.10.50.50.42.0-0.4-0.4-1.11.2-0.9-0.8-0.61.1-1.11.1-1.40.9-0.5-0.6
Bone: trabecular thickness0.40.63.20.4-0.7-0.6-0.9-0.8-0.3-0.5-0.31.8-0.0-0.90.0-1.7-0.1-0.20.8-1.61.20.10.6-0.20.2-0.20.6-0.00.1-0.5
Bone: trabecular tissue density0.10.32.30.3-0.1-0.0-0.11.5-0.2-0.2-0.3-0.30.50.40.20.4-0.2-0.2-1.20.30.3-0.10.50.3-0.30.3-0.30.40.9-0.8
Water consumed over 24 hours0.20.40.9-0.50.70.50.80.10.60.80.7-0.8-0.20.7-0.50.80.60.70.50.8-0.90.6-0.7-0.30.3-0.30.3-0.1-0.40.5
Number of responses in last shaping day0.91.25.3-0.51.20.81.50.50.91.10.7-2.1-0.61.4-0.92.30.90.8-0.31.9-2.10.7-1.3-0.20.2-0.2-0.1-0.3-0.50.8