Hub : Genes

D430041D05Rikl

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression D430041D05Rikl 0.44 0.2 1.2e-08 0.28 0.24 0.19 0.27 2.1e-07 1.9e-06 2.7e-05 3.1e-07
2 Brain mRNA stability D430041D05Rikl 0.09 0.07 1.7e-10 0.11 0.09 0.11 0.11 1.1e-10 4.6e-09 2.3e-10 1.2e-10
3 Brain isoform ratio NM_001419547.1 0.15 0.12 7.6e-13 0.12 0.14 0.14 0.13 2.4e-11 3.2e-13 1.0e-12 7.3e-12
4 Brain isoform ratio XM_039106456.2 0.06 0.04 1.9e-07 0.06 0.08 0.06 0.06 7.0e-06 4.3e-08 3.8e-06 2.3e-06
5 Brain isoform ratio XM_017592182.3 0.05 0.04 2.1e-05 0.04 0.05 0.04 0.04 4.7e-05 9.8e-06 7.3e-05 1.0e-04
6 NAcc gene expression D430041D05Rikl 0.17 0.12 0.0e+00 0.16 0.17 0.17 0.16 2.6e-23 9.2e-25 2.0e-24 2.9e-24
7 NAcc isoform ratio XM_039106456.2 0.01 0.01 9.3e-03 0 0 0 0 6.2e-02 4.4e-02 5.1e-02 6.6e-02
8 Brain gene expression D430041D05Rikl 0.09 0.05 6.3e-13 0.13 0.14 0.14 0.12 6.1e-12 7.3e-13 1.5e-12 5.0e-11
9 PL isoform ratio NM_001419547.1 0.03 0.03 1.1e-03 0.01 0.01 0.01 0 8.0e-03 1.0e-02 1.6e-02 3.4e-01
10 Brain isoform ratio XM_039106457.2 0.03 0.03 1.5e-03 0.02 0.02 0.01 0.01 2.3e-03 8.7e-03 1.7e-02 1.3e-02
11 pVTA isoform ratio NM_001419547.1 0.04 0.04 5.5e-03 0.03 0.01 0.02 0.01 3.9e-03 8.2e-02 1.5e-02 1.9e-02
12 pVTA mRNA stability D430041D05Rikl 0.18 0.08 1.2e-09 0.12 0.11 0.11 0.12 1.4e-09 4.2e-09 2.2e-09 1.4e-09
13 IC isoform ratio XM_017592182.3 0.11 0.08 3.6e-04 0.09 0.09 0.07 0.1 1.3e-04 9.2e-05 6.3e-04 5.5e-05
14 IC mRNA stability D430041D05Rikl 0.1 0.1 4.6e-03 0.04 0.05 0.03 0.04 6.1e-03 5.4e-03 1.8e-02 1.3e-02
15 IC isoform ratio NM_001419547.1 0.25 0.16 2.7e-08 0.2 0.16 0.19 0.15 1.3e-08 2.2e-07 1.7e-08 6.8e-07
16 pVTA isoform ratio XM_039106456.2 0.03 0.03 7.2e-03 0.02 0.02 0.01 0.02 6.7e-03 1.6e-02 6.1e-02 1.1e-02
17 NAcc mRNA stability D430041D05Rikl 0.09 0.07 6.0e-14 0.1 0.08 0.11 0.09 2.0e-14 4.6e-12 1.0e-15 7.6e-14
18 IC isoform ratio XM_039106456.2 0.31 0.32 1.2e-03 0.03 0.06 0.03 0.08 1.4e-02 1.7e-03 2.3e-02 3.2e-04
19 PL mRNA stability D430041D05Rikl 0.23 0.13 4.6e-10 0.07 0.08 0.08 0.02 1.9e-08 4.4e-09 1.0e-08 9.8e-04
20 BLA mRNA stability D430041D05Rikl 0.08 0.06 5.6e-04 0.04 0.01 0.04 0.05 2.2e-03 1.1e-01 3.1e-03 1.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.30.61.51.21.0-1.00.9-0.9-0.60.8-0.8-0.8-0.5-0.70.8-0.60.6-0.50.70.70.30.60.0
Area under the delay curve0.20.20.4-0.1-0.60.4-0.40.40.5-0.50.50.40.50.4-0.40.5-0.50.5-0.5-0.5-0.3-0.40.0
BMI with tail0.10.30.90.20.10.4-0.50.40.4-0.50.50.91.00.9-0.70.4-0.70.5-0.3-0.7-0.5-0.90.0
BMI without tail0.20.71.90.70.7-0.80.9-0.8-1.00.9-0.9-1.4-0.7-0.80.9-0.90.9-0.81.00.90.80.80.0
Body weight0.62.55.42.02.3-1.61.6-1.6-1.81.5-1.6-1.8-1.4-1.41.5-1.61.5-1.61.61.41.51.10.0
Weight adjusted by age1.72.54.3-0.4-1.01.4-1.51.51.4-1.61.52.11.72.0-2.01.6-1.81.8-1.4-1.8-1.6-2.10.0
Bone surface0.20.41.10.90.9-0.80.7-0.7-0.50.6-0.6-1.0-0.6-0.70.9-0.20.5-0.20.30.50.10.70.0
Bone volume0.61.11.81.31.2-1.31.2-1.2-0.91.1-1.0-1.2-0.9-1.21.2-0.71.0-0.70.81.00.61.10.0
Breakpoint value in progressive ratio session0.50.61.1-1.1-0.60.9-0.90.90.8-0.90.80.60.81.0-0.90.3-0.80.7-0.2-0.7-0.9-0.80.0
Number of licking bursts0.00.10.10.30.3-0.30.3-0.3-0.20.3-0.2-0.0-0.2-0.10.3-0.10.2-0.00.30.10.10.40.0
Context. condit. distance diff. score4.04.86.52.52.3-2.32.3-2.3-2.42.3-2.4-1.8-2.3-2.01.9-2.32.2-2.52.22.22.41.90.0
Locomotion velocity, session 10.40.52.2-1.3-1.50.9-0.60.70.6-0.60.60.60.20.2-0.40.8-0.20.4-1.0-0.6-0.50.10.0
Locomotion distance, session 10.20.30.5-0.4-0.70.4-0.40.40.6-0.50.50.50.70.4-0.30.6-0.50.6-0.5-0.5-0.6-0.40.0
Locomotion velocity, session 20.00.00.10.1-0.2-0.0-0.10.00.2-0.10.1-0.00.1-0.00.0-0.1-0.10.30.10.0-0.2-0.10.0
Locomotion distance, session 20.10.10.20.1-0.1-0.30.3-0.3-0.20.4-0.3-0.5-0.1-0.30.4-0.30.4-0.20.30.30.40.50.0
Locomotion velocity, session 30.30.31.00.60.10.2-0.30.30.6-0.50.50.40.60.3-0.30.9-0.70.8-1.0-0.6-0.8-0.60.0
Locomotion distance, session 30.00.00.10.3-0.2-0.20.1-0.10.10.00.00.1-0.1-0.20.10.3-0.10.2-0.30.1-0.2-0.00.0
Stereotopy head waving bouts, day 30.50.61.7-0.2-0.20.7-0.70.80.8-0.80.90.60.90.6-0.51.1-0.80.8-1.3-0.9-0.8-0.60.0
Stereotopy head waving duration, day 30.20.20.70.70.8-0.40.4-0.4-0.40.4-0.3-0.5-0.2-0.40.5-0.10.4-0.4-0.00.20.50.40.0
Locomotion velocity, session 70.20.20.50.60.4-0.40.4-0.4-0.50.4-0.50.0-0.4-0.20.2-0.50.4-0.60.70.50.70.10.0
Locomotion distance, session 70.10.10.4-0.4-0.50.2-0.30.20.1-0.20.10.50.30.5-0.6-0.0-0.2-0.00.1-0.10.1-0.60.0
Stereotopy head waving bouts, day 70.20.20.90.10.00.3-0.40.40.5-0.50.60.20.30.2-0.10.9-0.50.7-0.9-0.6-0.8-0.20.0
Stereotopy head waving duration, day 70.10.10.50.10.10.2-0.20.30.3-0.30.4-0.10.1-0.10.20.7-0.20.4-0.7-0.3-0.50.00.0
Locomotion velocity, session 80.60.71.20.60.3-0.70.8-0.8-0.90.8-0.9-0.7-1.1-1.10.8-0.81.0-1.00.70.91.10.90.0
Locomotion distance, session 82.94.24.92.21.8-2.22.2-2.2-2.12.2-2.2-2.0-2.0-2.02.0-2.22.1-2.12.12.12.12.00.0
Degree of sensitization distance0.20.20.7-0.6-0.10.10.1-0.1-0.40.3-0.4-0.1-0.20.1-0.2-0.70.5-0.80.80.30.80.20.0
Degree of sensitization stereotypy0.30.31.0-0.3-0.20.5-0.50.60.7-0.60.70.20.40.3-0.10.9-0.50.8-1.0-0.6-0.8-0.20.0
Conditioned locomotion5.86.610.8-2.9-2.62.8-2.72.82.7-2.72.82.22.32.2-2.13.0-2.52.6-3.3-2.7-2.7-2.10.0
Cocaine response after cond. corrected2.83.45.4-2.3-1.71.9-2.02.02.0-1.91.91.62.01.9-1.81.9-1.91.8-1.7-1.8-1.9-1.80.0
Cocaine response after cond. not corrected0.60.71.6-1.3-0.50.9-0.90.90.9-0.90.90.61.00.8-0.70.8-0.80.8-0.7-0.8-0.9-0.80.0
Cocaine response before conditioning5.97.08.12.92.7-2.82.8-2.8-2.72.8-2.7-2.6-2.6-2.72.8-2.72.7-2.62.72.72.62.70.0
Saline control response0.30.41.20.40.2-0.50.6-0.5-0.40.6-0.4-1.1-0.7-1.11.1-0.20.7-0.50.10.60.41.00.0
Bone: connectivity density0.30.51.51.20.9-1.00.8-0.8-0.60.7-0.7-0.9-0.5-0.60.8-0.40.6-0.40.60.60.30.50.0
Bone: cortical apparent density0.20.20.50.20.5-0.40.4-0.4-0.60.5-0.5-0.2-0.5-0.10.1-0.70.5-0.70.70.40.60.20.0
Bone: cortical area0.91.42.41.11.2-1.11.2-1.1-1.31.2-1.2-1.3-1.6-1.31.1-1.11.2-1.21.11.31.11.10.0
Bone: cortical porosity0.20.20.4-0.5-0.50.4-0.50.40.6-0.40.40.60.40.5-0.50.4-0.50.6-0.4-0.4-0.5-0.40.0
Bone: cortical porosity0.10.10.2-0.2-0.40.2-0.30.30.3-0.30.30.50.10.3-0.40.2-0.30.4-0.1-0.2-0.3-0.30.0
Bone: cortical thickness0.20.30.70.40.5-0.50.5-0.5-0.60.5-0.5-0.7-0.9-0.80.6-0.50.6-0.50.40.70.40.60.0
Bone: cortical thickness2.22.53.7-1.3-1.21.6-1.71.61.6-1.71.61.71.61.7-1.71.6-1.71.9-1.5-1.6-1.9-1.80.0
Bone: cortical tissue density0.10.20.50.20.5-0.40.4-0.4-0.60.4-0.5-0.2-0.5-0.10.1-0.60.5-0.70.70.40.60.20.0
Condit. Reinf. active minus inactive responses1.41.63.31.81.7-1.51.4-1.4-1.31.3-1.3-1.0-1.2-1.01.1-1.31.2-1.11.31.21.11.10.0
Condit. Reinf. active-inactive response ratio3.94.28.72.92.9-2.42.2-2.3-2.22.1-2.2-1.6-1.8-1.61.6-2.21.8-1.92.21.91.91.50.0
Condit. Reinf. active responses0.30.40.60.80.6-0.70.7-0.7-0.60.7-0.7-0.5-0.6-0.60.6-0.50.7-0.40.60.60.50.70.0
Condit. Reinf. inactive responses0.70.82.4-1.5-1.51.1-1.01.01.0-0.91.00.60.80.6-0.51.1-0.60.9-1.0-0.7-0.9-0.30.0
Incentive salience index mean1.31.62.41.61.4-1.41.4-1.4-1.31.3-1.3-1.1-1.2-1.21.2-1.21.3-1.11.21.31.11.30.0
Condit. Reinf. lever presses0.71.01.90.80.7-1.01.1-1.0-1.11.1-1.0-0.9-0.9-1.31.3-0.81.2-1.00.91.11.01.40.0
Condit. Reinf. active minus inactive responses1.51.92.71.51.6-1.51.5-1.5-1.51.5-1.5-1.4-1.4-1.01.2-1.51.4-1.41.51.31.31.30.0
Condit. Reinf. active-inactive response ratio4.65.36.22.22.4-2.42.4-2.4-2.52.4-2.5-2.3-2.4-2.12.3-2.52.4-2.32.42.32.32.20.0
Condit. Reinf. active responses0.71.02.01.41.4-1.11.1-1.1-1.11.1-1.1-1.0-1.0-0.60.8-1.01.0-0.91.20.80.80.90.0
Condit. Reinf. inactive responses0.30.40.80.0-0.20.5-0.60.60.7-0.60.70.70.70.8-0.70.8-0.70.9-0.6-0.8-0.8-0.70.0
Condit. Reinf. lever presses1.01.42.71.61.5-1.31.3-1.3-1.31.3-1.3-0.8-1.2-0.60.8-1.41.2-1.31.51.01.21.00.0
Condit. Reinf. lever reinforcers received0.70.92.21.51.4-1.11.0-1.1-1.01.0-1.1-0.8-0.9-0.50.7-1.00.9-0.91.10.70.80.80.0
Conditioned reinforcement - actives3.66.29.92.82.2-2.62.6-2.6-2.72.6-2.5-3.2-2.7-2.72.8-2.22.6-2.32.22.42.22.60.0
Conditioned reinforcement - inactives4.97.210.93.32.4-3.13.0-3.0-2.82.8-2.8-2.8-2.4-2.82.8-2.52.6-2.72.52.72.62.40.0
Conditioned locomotion1.01.35.52.31.8-1.51.3-1.3-1.11.1-1.1-1.1-0.7-0.70.8-0.90.7-0.90.90.70.80.50.0
Patch foraging indifference point 0 sec1.01.83.0-0.1-0.50.9-1.11.11.5-1.31.41.01.71.6-1.41.7-1.61.5-1.6-1.7-1.5-1.70.0
Patch foraging indifference point AUC0.40.61.5-1.2-0.81.0-0.91.00.7-0.90.90.60.60.5-0.50.6-0.80.8-0.7-0.6-0.9-0.70.0
Delay disc. indifference point, 0s delay0.10.10.50.4-0.2-0.40.3-0.3-0.20.3-0.3-0.3-0.2-0.20.2-0.60.2-0.30.70.40.50.00.0
Delay disc. indifference point, 16s delay0.91.01.8-0.5-0.81.0-1.11.11.0-1.11.11.11.11.0-1.11.1-1.20.9-1.1-1.1-0.7-1.30.0
Delay disc. indifference point, 2s delay0.10.10.40.2-0.00.2-0.20.20.1-0.20.20.60.20.2-0.40.1-0.30.2-0.1-0.2-0.2-0.40.0
Delay disc. indifference point, 24s delay0.40.51.5-0.5-0.70.7-0.70.70.7-0.70.80.40.60.6-0.51.1-0.60.8-1.2-0.9-0.7-0.40.0
Delay disc. indifference point, 4s delay0.30.30.7-0.4-0.90.6-0.60.60.6-0.60.60.40.60.5-0.50.6-0.60.7-0.5-0.5-0.5-0.40.0
Delay disc. indifference point, 8s delay0.00.00.20.2-0.1-0.20.2-0.20.00.2-0.1-0.3-0.1-0.20.3-0.30.2-0.20.30.20.40.30.0
Indifference point function ln k0.50.91.81.30.9-1.11.1-1.1-0.91.0-1.0-1.0-0.7-0.70.8-0.90.9-1.20.90.91.20.80.0
Indifference point function log k0.50.91.81.30.9-1.11.1-1.1-0.91.0-1.0-1.0-0.7-0.70.8-0.90.9-1.20.90.91.20.80.0
Patch foraging total patch changes 0 sec0.91.72.8-0.0-0.50.8-1.11.01.4-1.21.30.91.71.5-1.31.6-1.61.5-1.6-1.7-1.4-1.60.0
Patch foraging total patch changes 12 sec0.00.00.20.20.3-0.00.00.00.0-0.00.10.00.1-0.20.20.1-0.10.30.0-0.0-0.4-0.00.0
Patch foraging total patch changes 18 sec0.71.01.8-0.30.00.8-1.01.01.1-1.11.10.41.10.9-0.71.2-1.21.3-1.3-1.3-1.4-1.20.0
Patch foraging total patch changes 24 sec1.22.13.3-0.4-0.31.2-1.41.41.5-1.51.61.31.81.6-1.41.6-1.81.7-1.7-1.8-1.7-1.80.0
Patch foraging total patch changes 6 sec0.61.01.9-0.5-0.60.7-0.90.91.2-1.11.10.71.20.9-0.81.0-1.31.3-0.9-1.1-1.3-1.40.0
Patch foraging time to switch 0 sec0.00.10.60.60.7-0.40.2-0.2-0.10.1-0.10.20.10.2-0.2-0.1-0.20.20.40.0-0.2-0.30.0
Patch foraging water rate 0 sec0.00.00.1-0.10.00.1-0.20.20.3-0.20.2-0.20.30.3-0.20.1-0.30.0-0.2-0.2-0.1-0.30.0
Patch foraging water rate 12 sec0.00.00.10.10.10.1-0.10.1-0.0-0.10.0-0.10.00.2-0.2-0.2-0.0-0.20.0-0.00.2-0.20.0
Patch foraging water rate 18 sec0.50.81.60.70.8-0.81.0-0.9-1.11.0-1.0-1.1-1.0-0.91.0-0.71.2-0.90.70.90.91.30.0
Patch foraging water rate 24 sec0.20.31.20.30.4-0.30.4-0.4-0.70.5-0.6-0.4-0.5-0.30.2-0.60.6-1.10.60.51.10.30.0
Patch foraging water rate 6 sec0.00.00.30.1-0.20.1-0.10.00.1-0.00.0-0.20.10.1-0.10.1-0.0-0.4-0.2-0.00.5-0.10.0
Seeking ratio, delayed vs. immediate footshock0.30.40.90.30.5-0.60.6-0.6-0.60.6-0.7-0.1-0.6-0.50.3-0.90.5-1.00.70.60.90.30.0
Distance traveled before self-admin0.00.10.50.60.7-0.10.1-0.1-0.20.0-0.1-0.10.00.1-0.2-0.00.0-0.2-0.10.00.0-0.10.0
Distance traveled after self-admin0.40.51.11.01.1-0.60.6-0.6-1.00.6-0.7-0.9-0.9-0.80.6-0.60.7-0.60.60.70.40.60.0
Extensor digitorum longus weight0.10.51.0-0.8-0.60.6-0.80.70.8-0.80.80.21.00.5-0.50.9-0.80.9-0.8-0.6-1.0-0.80.0
Bone: elastic displacement0.50.51.0-0.6-0.60.8-0.80.80.7-0.80.70.90.50.9-1.00.6-0.80.7-0.6-0.7-0.9-0.90.0
Bone: elastic work0.50.61.40.10.00.6-0.70.70.5-0.70.61.20.71.0-1.10.7-0.90.8-0.8-0.8-1.0-1.20.0
Bone: endosteal estimation0.10.30.5-0.2-0.30.5-0.60.50.5-0.60.60.70.40.6-0.60.6-0.60.5-0.6-0.6-0.6-0.70.0
Bone: endosteal perimeter0.20.41.00.60.4-0.70.7-0.7-0.60.7-0.7-0.6-1.0-0.70.8-0.50.7-0.60.40.60.50.80.0
Epididymis fat weight1.23.95.72.32.4-2.12.1-2.1-2.12.1-2.1-2.1-2.0-1.92.0-1.92.0-1.72.12.01.81.90.0
Delta time in closed arm before/after self-admin0.30.30.7-0.4-0.50.6-0.50.60.4-0.50.50.40.60.3-0.40.8-0.40.5-0.8-0.6-0.6-0.50.0
Delta time in open arm before/after self-admin0.10.10.7-0.3-0.20.3-0.30.30.5-0.30.40.80.20.2-0.20.5-0.20.3-0.5-0.3-0.20.20.0
Diff in mean of infusions in LGA sessions0.40.51.6-0.4-0.10.7-0.80.80.6-0.80.70.80.60.8-0.90.5-0.81.1-0.2-0.6-1.3-0.90.0
Delay discount exponential model param0.30.30.40.20.6-0.50.5-0.6-0.60.6-0.6-0.4-0.6-0.50.5-0.60.6-0.60.60.60.40.40.0
Extinction: sum of active levers before priming0.00.00.2-0.20.10.2-0.20.2-0.0-0.20.1-0.00.20.3-0.3-0.2-0.1-0.30.1-0.10.0-0.40.0
Active lever presses in extinction session 60.10.10.40.30.5-0.40.3-0.3-0.30.2-0.3-0.3-0.20.1-0.1-0.60.1-0.20.60.20.1-0.10.0
Bone: final force0.20.40.70.60.5-0.50.6-0.6-0.80.6-0.7-0.3-0.9-0.60.4-0.70.7-0.90.60.60.80.40.0
Bone: final moment0.10.20.50.50.4-0.40.4-0.4-0.70.4-0.5-0.1-0.7-0.30.1-0.60.4-0.70.50.40.60.10.0
Food consumed during 24 hour testing period6.08.210.91.92.2-2.83.0-2.9-3.03.0-3.0-3.1-3.1-3.23.2-2.73.2-3.02.83.12.93.30.0
Glucose3.04.76.21.92.1-2.12.2-2.2-2.32.3-2.3-2.3-2.2-2.12.1-2.42.3-2.52.32.32.42.20.0
Heart weight0.40.71.4-0.8-0.90.8-0.70.80.7-0.80.71.20.71.0-1.10.8-0.70.6-0.8-1.0-0.7-0.80.0
Delay discount hyperbolic model param0.30.40.60.30.7-0.60.6-0.6-0.70.6-0.7-0.6-0.6-0.60.6-0.70.6-0.60.70.60.50.50.0
Intermittent access intake day 1-15 change0.20.41.41.20.9-0.90.8-0.8-0.70.7-0.7-0.3-0.6-0.40.5-0.60.5-0.60.50.50.50.40.0
Intermittent access intake escalation0.40.81.91.41.1-1.21.0-1.1-0.90.9-0.9-0.6-0.8-0.50.7-0.80.7-0.80.80.70.80.60.0
Intermittent access intake escalation 21.31.51.91.20.9-1.41.4-1.4-1.31.4-1.4-1.2-1.3-1.01.2-1.21.4-1.31.21.21.31.40.0
Intermitt. access day 1 inactive lever presses0.52.04.11.61.8-1.61.3-1.5-1.51.3-1.5-0.8-0.9-1.10.7-1.90.9-1.91.91.62.0-0.00.0
Intermitt. access day 15 inactive lever presses0.61.22.41.31.5-1.21.1-1.2-1.21.1-1.2-0.8-0.9-1.00.9-1.30.9-1.11.21.11.20.70.0
Intermitt. access escalation Index0.20.21.2-0.9-0.80.3-0.10.20.10.00.1-0.6-0.5-0.60.60.40.40.3-0.40.1-0.41.10.0
Intermittent access day 1 total infusions2.33.76.22.02.1-2.22.0-2.0-1.81.9-1.8-2.5-1.7-2.32.4-1.81.8-1.91.72.01.71.80.0
Intermittent access day 15 total infusions2.43.55.62.42.1-2.22.1-2.1-1.82.0-1.9-2.0-1.9-2.02.2-1.61.8-1.61.51.81.51.90.0
Intermittent access terminal intake (last 3 days)2.53.35.41.91.7-2.02.0-1.9-1.81.9-1.8-2.3-1.9-2.12.3-1.51.9-1.61.31.71.52.20.0
Intermittent access total infusions3.44.16.62.11.7-2.22.1-2.1-1.92.1-1.9-2.6-2.0-2.42.6-1.82.0-1.81.62.01.72.20.0
Intermittent access day 1 locomotion1.11.43.21.81.3-1.61.3-1.4-1.01.2-1.1-1.4-0.8-1.21.4-1.20.9-1.11.21.21.00.80.0
Intermittent access day 15 total locomotion0.10.11.11.10.4-0.50.3-0.30.00.2-0.1-0.20.2-0.20.40.1-0.00.3-0.3-0.0-0.30.10.0
Intermittent access total locomotion0.70.94.02.01.1-1.41.1-1.2-0.70.9-0.9-0.9-0.4-0.70.8-0.90.5-0.70.80.70.60.40.0
Intermittent access standard deviation1.53.14.51.71.8-1.91.9-1.9-1.81.9-1.8-2.1-1.9-1.71.9-1.61.9-1.81.51.71.71.90.0
Left kidney weight1.15.27.72.02.5-2.22.3-2.3-2.62.3-2.4-2.8-2.5-2.32.2-2.12.4-2.41.92.32.42.20.0
Right kidney weight1.46.69.12.73.0-2.62.7-2.7-2.92.7-2.7-2.7-2.7-2.52.4-2.62.6-2.72.52.52.72.20.0
Cocaine induced anxiety0.00.00.30.5-0.2-0.00.1-0.1-0.30.1-0.20.2-0.10.0-0.2-0.30.0-0.00.40.1-0.0-0.30.0
Post-drug Anxiety0.50.61.3-0.4-0.50.7-0.80.80.6-0.80.71.00.80.9-0.90.4-0.90.9-0.2-0.6-0.9-1.10.0
Baseline Anxiety1.41.63.3-1.8-1.01.2-1.31.31.6-1.31.40.71.21.1-0.91.3-1.21.6-1.2-1.2-1.5-0.80.0
Tail length1.34.911.41.21.9-2.02.1-2.1-2.32.2-2.2-3.4-2.5-2.62.5-2.22.4-2.12.12.42.12.40.0
Length with tail1.77.612.12.73.5-2.82.7-2.7-2.92.7-2.8-3.4-2.7-3.02.9-2.72.7-2.72.62.82.72.40.0
Length without tail0.92.89.32.33.0-1.91.7-1.7-1.61.6-1.7-1.4-1.4-1.31.4-1.71.3-1.61.71.51.61.00.0
Times rat made contact with spout0.20.20.40.60.6-0.60.5-0.5-0.40.5-0.5-0.4-0.5-0.50.5-0.50.4-0.30.50.50.40.30.0
Lifetime Intake3.54.37.02.01.6-2.22.2-2.1-1.92.1-2.0-2.6-2.1-2.52.7-1.92.1-1.91.82.11.82.30.0
Liver weight, left2.23.65.02.12.2-1.91.9-2.0-2.11.9-2.0-1.7-2.0-1.71.6-2.11.8-2.12.21.92.21.50.0
Liver weight, right1.93.34.61.61.9-1.71.8-1.9-2.21.9-2.0-1.7-1.9-1.81.5-2.01.9-2.11.92.02.11.50.0
Locomotor activity0.00.00.1-0.1-0.10.0-0.00.10.2-0.10.10.20.20.2-0.20.2-0.00.1-0.3-0.2-0.10.10.0
Locomotor testing distance1.32.44.12.02.0-1.81.6-1.7-1.51.6-1.6-1.2-1.3-1.41.3-1.61.4-1.61.61.51.71.20.0
Locomotor testing rearing0.20.51.41.01.2-0.70.7-0.8-0.80.7-0.8-0.1-0.3-0.40.5-0.70.7-1.00.60.51.00.40.0
Locomotion in novel chamber0.30.40.70.70.5-0.80.7-0.7-0.50.7-0.6-0.8-0.5-0.50.7-0.60.6-0.50.80.70.40.80.0
Locomotion in novel chamber post-restriction0.40.71.3-1.1-1.10.9-0.90.90.9-0.90.90.80.90.6-0.70.6-0.90.8-0.6-0.7-0.9-0.90.0
Fecal boli incidents, locomotor time 12.63.85.3-2.1-2.02.3-2.22.21.9-2.22.11.82.01.7-1.91.8-2.01.8-1.8-1.8-1.8-2.10.0
Change in fecal boli incidents, locomotor task1.71.63.01.50.9-1.61.5-1.5-1.11.4-1.3-1.7-1.3-1.31.6-1.01.4-0.91.01.10.71.70.0
Time >=10cm from walls, locomotor time 10.10.10.7-0.8-0.60.3-0.20.20.1-0.10.10.1-0.1-0.20.20.10.2-0.0-0.10.10.10.30.0
Bouts of movement, locomotor time 10.00.00.10.20.3-0.1-0.10.0-0.0-0.00.0-0.10.0-0.20.2-0.1-0.10.00.10.10.2-0.20.0
Total resting periods, locomotor time 10.00.00.10.10.30.00.0-0.0-0.20.0-0.1-0.3-0.2-0.30.3-0.10.1-0.20.10.20.40.00.0
Rest time, locomotor task time 10.40.53.0-1.7-1.41.2-0.70.90.3-0.50.6-0.2-0.2-0.10.10.80.10.3-1.0-0.4-0.30.60.0
Distance moved, locomotor task time 11.01.52.41.41.3-1.61.4-1.5-1.21.3-1.4-0.9-1.1-1.01.0-1.41.1-1.11.51.21.11.00.0
Vertical activity count, locomotor time 10.10.10.50.50.4-0.60.3-0.40.00.2-0.30.4-0.10.1-0.1-0.6-0.1-0.20.70.30.1-0.30.0
Time >=10cm from walls, locomotor time 24.05.98.51.62.0-2.32.5-2.4-2.42.5-2.5-2.6-2.6-2.72.7-2.52.7-2.62.52.62.42.90.0
Bouts of movement, locomotor time 20.20.41.81.31.2-0.50.2-0.4-0.40.1-0.30.40.10.2-0.5-0.7-0.3-0.40.80.20.5-1.10.0
Total resting periods, locomotor time 20.20.41.91.41.2-0.60.3-0.5-0.50.2-0.40.30.00.1-0.3-0.8-0.2-0.30.90.40.5-0.90.0
Rest time, locomotor task time 22.02.53.8-1.9-1.91.8-1.71.71.6-1.61.71.31.41.3-1.31.9-1.41.7-1.9-1.6-1.4-1.20.0
Distance moved, locomotor task time 25.36.38.51.82.3-2.52.6-2.6-2.52.6-2.6-2.7-2.7-2.52.5-2.92.7-2.72.92.62.42.80.0
Vertical activity count, locomotor time 22.53.55.61.72.3-2.01.9-1.9-1.81.9-1.9-1.5-2.0-1.61.5-2.31.7-2.22.41.91.81.50.0
Light reinforcement 10.20.51.00.50.7-0.40.6-0.6-0.90.7-0.7-0.8-1.0-0.80.7-0.41.0-1.00.20.51.00.90.0
Light reinforcement 20.30.41.7-0.7-0.60.10.3-0.2-0.60.5-0.5-0.3-1.0-0.90.6-0.31.0-0.50.10.70.51.30.0
Bone: marrow area0.10.30.5-0.3-0.30.5-0.60.60.6-0.60.60.70.40.6-0.60.7-0.70.6-0.7-0.6-0.7-0.70.0
Bone: maximum diameter0.50.91.90.70.6-0.80.9-0.9-1.01.0-1.0-1.1-1.4-1.00.9-0.81.1-1.00.81.00.91.10.0
Bone: maximum force0.20.31.01.00.7-0.60.7-0.6-0.80.6-0.6-0.6-0.7-0.50.4-0.60.5-0.50.40.50.40.40.0
Bone: maximum moment0.10.10.70.80.5-0.30.3-0.3-0.50.3-0.3-0.3-0.4-0.10.0-0.30.2-0.20.20.20.1-0.10.0
Mean time between licks in bursts0.71.72.8-0.9-0.81.1-1.31.21.3-1.31.31.31.71.4-1.31.2-1.51.5-1.2-1.3-1.4-1.60.0
Mean num. licks in bursts0.10.10.20.20.3-0.20.2-0.2-0.20.2-0.3-0.5-0.3-0.40.2-0.40.2-0.40.10.40.40.10.0
Cd content in liver4.04.56.71.11.5-1.92.1-2.1-2.22.2-2.2-2.1-2.0-2.32.1-2.32.4-2.52.42.42.62.40.0
Co content in liver0.81.01.5-1.1-0.81.0-1.11.01.1-1.01.01.01.11.0-1.10.7-1.11.1-0.8-0.9-1.2-1.10.0
Cu content in liver0.50.61.7-1.3-0.81.0-0.90.90.9-0.90.80.70.70.9-1.00.4-0.80.8-0.4-0.7-0.6-0.80.0
Fe content in liver0.10.10.2-0.20.40.1-0.20.10.2-0.20.10.30.20.4-0.4-0.3-0.30.20.2-0.1-0.1-0.40.0
K content in liver3.02.95.8-0.8-1.21.5-1.71.61.7-1.81.71.91.82.0-2.11.5-2.01.9-1.4-1.7-1.6-2.40.0
Mg content in liver0.30.41.1-0.2-0.40.6-0.70.60.5-0.70.60.70.60.7-0.80.3-0.80.7-0.2-0.5-0.3-1.00.0
Mn content in liver0.50.61.5-0.7-1.21.0-0.80.90.6-0.80.80.80.60.7-0.90.7-0.70.6-0.7-0.7-0.5-0.80.0
Na content in liver1.01.02.11.31.5-1.11.0-1.0-1.10.9-1.0-0.9-1.2-1.00.8-1.10.8-0.81.31.20.90.40.0
Rb content in liver0.80.91.4-1.1-0.91.1-1.11.10.9-1.00.90.90.81.0-1.20.6-1.01.0-0.6-0.8-0.8-1.10.0
Se content in liver5.05.96.8-2.5-2.42.5-2.52.52.6-2.52.52.52.62.6-2.52.4-2.52.5-2.4-2.6-2.5-2.40.0
Sr content in liver0.10.10.3-0.0-0.00.1-0.20.20.3-0.30.20.50.30.3-0.30.2-0.40.30.0-0.2-0.4-0.50.0
Zn content in liver0.30.40.7-0.30.2-0.40.5-0.5-0.60.6-0.6-0.7-0.7-0.60.5-0.70.8-0.80.70.60.80.80.0
Bone: minimum diameter1.42.63.91.51.6-1.71.6-1.6-1.71.6-1.6-1.9-2.0-1.91.8-1.71.6-1.51.51.81.41.50.0
Time in familiar zone, hab. session 10.50.50.9-0.9-1.00.8-0.80.80.8-0.80.80.50.80.4-0.60.7-0.70.7-0.8-0.6-0.6-0.60.0
Time in novel zone, hab. session 11.01.01.81.21.3-1.11.1-1.1-1.11.1-1.1-0.7-1.1-0.60.8-1.11.0-1.11.10.80.90.90.0
Total zone transitions, hab. session 11.01.33.21.81.3-1.41.3-1.3-1.11.3-1.2-1.1-1.1-1.01.2-1.01.1-0.91.11.01.01.10.0
Total locomotion distance, hab. session 10.10.10.50.70.2-0.30.1-0.10.3-0.00.1-0.30.40.20.10.2-0.30.4-0.2-0.3-0.3-0.20.0
Locomotion velocity, hab. session 10.10.20.50.60.1-0.2-0.10.00.5-0.20.3-0.00.70.5-0.20.3-0.50.6-0.3-0.5-0.5-0.40.0
Time in familiar zone, hab. session 20.30.30.8-0.6-0.80.5-0.50.50.6-0.50.50.50.60.5-0.40.5-0.40.5-0.9-0.5-0.5-0.30.0
Time in novel zone, hab. session 20.70.71.30.50.8-0.60.7-0.7-1.00.8-0.8-0.8-1.1-0.90.8-0.80.9-1.01.10.81.00.80.0
Total zone transitions, hab. session 21.11.42.30.90.8-1.11.2-1.2-1.21.2-1.2-1.2-1.5-1.41.5-0.81.3-1.10.91.21.21.50.0
Total locomotion distance, hab. session 20.30.30.8-0.7-0.90.6-0.60.60.7-0.60.70.40.40.3-0.20.9-0.50.6-0.8-0.6-0.5-0.30.0
Locomotion velocity, hab. session 20.30.40.9-0.6-0.80.6-0.60.60.8-0.60.70.50.60.4-0.30.9-0.60.7-0.8-0.6-0.6-0.50.0
Novel to familiar place preference ratio0.80.92.61.61.6-1.31.1-1.2-1.01.0-1.1-0.3-0.4-0.60.6-1.00.7-0.91.10.80.90.30.0
Novelty place preference1.01.13.01.71.7-1.41.2-1.3-1.11.1-1.2-0.4-0.5-0.60.6-1.10.7-0.91.20.91.00.30.0
Time in novel zone, NPP test0.80.92.41.61.5-1.21.1-1.1-1.01.0-1.1-0.3-0.4-0.50.5-1.00.7-0.91.10.81.00.30.0
Total zone transitions, NPP test1.11.62.8-1.4-1.71.3-1.31.31.5-1.31.41.11.21.2-1.11.4-1.21.5-1.3-1.2-1.5-0.90.0
Total locomotion distance, NPP test1.72.43.9-1.8-2.01.6-1.61.61.9-1.61.71.21.51.4-1.21.6-1.61.7-1.6-1.5-1.7-1.20.0
Locomotion velocity, NPP test1.52.13.5-1.6-1.91.4-1.51.51.8-1.51.61.11.51.3-1.11.5-1.51.7-1.4-1.4-1.6-1.20.0
Intraocular pressure0.30.40.9-0.8-0.90.7-0.50.60.6-0.50.60.70.50.5-0.50.9-0.30.5-0.9-0.8-0.5-0.10.0
Delta distance traveled before/after self-admin0.10.20.40.00.1-0.20.3-0.2-0.60.3-0.3-0.6-0.6-0.60.6-0.30.4-0.10.30.40.10.50.0
Delta ambulatory time before/after self-admin0.40.50.90.40.5-0.50.6-0.6-0.90.7-0.7-0.8-0.9-0.80.8-0.70.8-0.50.80.80.50.70.0
Parametrial fat weight0.00.10.2-0.20.3-0.10.1-0.1-0.00.2-0.1-0.3-0.1-0.20.4-0.30.2-0.30.20.10.20.40.0
Pavlov. Cond. lever latency0.81.01.9-0.9-1.01.0-1.01.01.0-1.01.01.11.01.4-1.20.9-1.00.7-1.0-1.2-0.8-1.10.0
Pavlov. Cond. magazine entry latency1.52.03.01.51.5-1.31.4-1.3-1.61.4-1.4-1.3-1.5-1.71.4-1.41.5-1.41.31.51.41.40.0
Pavlov. Cond. change in total contacts0.00.00.10.20.20.2-0.20.20.0-0.20.20.40.2-0.1-0.20.3-0.20.4-0.3-0.1-0.2-0.20.0
Pavlov. Cond. index score0.60.71.60.90.8-0.80.8-0.8-1.00.8-0.8-0.8-0.9-1.31.0-0.80.9-0.70.81.10.70.90.0
Pavlov. Cond. latency score0.60.81.60.90.9-0.80.9-0.8-1.00.9-0.9-0.9-0.9-1.31.0-0.90.9-0.70.91.10.81.00.0
Pavlov. Cond. lever contacts0.81.02.01.00.9-1.01.0-1.0-1.11.0-1.0-1.0-1.0-1.41.1-0.91.0-0.81.01.20.91.10.0
Pavlov. Cond. magazine entry number1.82.33.2-1.7-1.71.4-1.51.51.8-1.51.61.31.71.8-1.51.5-1.61.5-1.4-1.7-1.5-1.50.0
Pavlov. Cond. intertrial magazine entries0.10.10.50.1-0.20.0-0.20.10.5-0.30.30.60.40.6-0.50.2-0.50.3-0.1-0.4-0.2-0.70.0
Pavlov. Cond. lever-magazine prob. diff.0.40.61.50.80.7-0.70.7-0.7-0.80.7-0.7-0.7-0.8-1.20.9-0.60.8-0.50.60.90.60.90.0
Pavlov. Cond. response bias1.61.93.31.41.4-1.31.4-1.3-1.51.4-1.4-1.3-1.5-1.81.5-1.31.4-1.31.31.61.31.40.0
Pavlov. Cond. lever latency1.62.23.3-1.7-1.51.6-1.61.61.5-1.61.61.01.41.0-1.21.8-1.51.8-1.8-1.4-1.6-1.40.0
Pavlov. Cond. magazine entry latency0.50.61.41.00.9-0.90.9-0.9-0.80.9-0.9-0.6-0.6-0.30.5-1.20.7-0.91.00.60.80.60.0
Pavlov. Cond. change in total contacts0.61.01.70.80.7-1.01.0-1.0-1.01.1-1.0-1.0-1.0-0.81.0-1.11.1-1.31.10.91.11.10.0
Pavlov. Cond. index score1.62.13.51.61.6-1.61.6-1.6-1.51.6-1.6-1.1-1.3-1.01.2-1.91.4-1.71.81.31.51.30.0
Pavlov. Cond. latency score1.72.23.21.61.5-1.61.6-1.6-1.51.6-1.6-1.3-1.4-1.11.4-1.81.5-1.61.71.41.51.50.0
Pavlov. Cond. lever contacts2.23.14.42.01.8-1.91.9-1.9-1.81.9-1.9-1.3-1.7-1.31.5-2.11.8-2.02.11.61.91.70.0
Pavlov. Cond. magazine entry number0.70.81.7-1.1-0.91.0-1.01.01.0-1.01.00.60.80.5-0.61.3-0.91.1-1.2-0.8-1.0-0.70.0
Pavlov. Cond. intertrial magazine entries0.00.00.20.30.10.1-0.20.10.1-0.10.10.40.10.1-0.20.0-0.20.20.10.0-0.1-0.40.0
Pavlov. Cond. lever-magazine prob. diff.1.51.93.21.61.5-1.51.5-1.5-1.41.5-1.5-1.0-1.3-0.91.1-1.81.4-1.61.81.31.41.30.0
Pavlov. Cond. response bias2.33.15.22.01.9-1.81.9-1.9-1.81.9-1.9-1.2-1.6-1.21.3-2.31.8-2.12.21.61.91.50.0
Time in closed arm before self-admin3.95.08.42.82.9-2.52.4-2.4-2.32.3-2.3-1.8-2.4-2.02.0-2.42.1-2.22.42.12.41.80.0
Time in closed arm after self-admin1.11.24.22.02.0-1.21.2-1.2-1.31.0-1.0-0.8-1.1-1.01.0-0.70.9-0.90.70.71.00.60.0
Time in open arm before self-admin5.35.87.5-2.7-2.62.4-2.52.52.6-2.52.52.02.62.5-2.42.2-2.52.4-2.2-2.4-2.7-2.40.0
Time in open arm after self-admin4.65.07.6-2.6-2.82.3-2.32.32.6-2.32.32.42.32.1-2.12.3-2.12.2-2.3-2.1-2.3-1.70.0
Bone: periosteal estimation0.00.00.20.30.3-0.10.1-0.1-0.20.1-0.1-0.2-0.5-0.20.1-0.00.1-0.10.00.20.00.10.0
Bone: periosteal perimeter1.11.93.41.10.9-1.31.4-1.3-1.41.4-1.3-1.6-1.8-1.71.7-1.21.6-1.31.11.51.01.80.0
Bone: post-yield work0.10.10.3-0.2-0.50.3-0.20.20.2-0.20.3-0.10.40.2-0.10.6-0.10.3-0.6-0.4-0.30.00.0
Progressive ratio test 1 active lever presses2.93.66.11.51.2-1.81.9-1.9-1.91.9-1.8-2.4-2.1-2.52.4-1.62.1-1.81.52.01.62.30.0
Progressive ratio test 1 breakpoint3.13.86.71.51.2-1.92.0-1.9-2.02.0-1.9-2.5-2.2-2.62.5-1.62.2-1.91.52.11.72.40.0
Progressive ratio test 1 inactive lever presses1.31.93.51.81.1-1.51.5-1.4-1.51.4-1.4-1.4-1.4-1.91.5-1.11.3-1.31.11.51.21.10.0
Progressive ratio test 2 active lever presses5.56.48.32.92.4-2.72.7-2.7-2.62.6-2.6-2.7-2.6-2.82.8-2.42.6-2.52.32.52.42.60.0
Progressive ratio test 2 breakpoint5.76.58.42.92.4-2.72.7-2.7-2.62.7-2.6-2.8-2.7-2.82.9-2.42.6-2.52.32.52.42.70.0
Progressive ratio test 2 inactive lever presses3.55.69.03.02.6-2.62.5-2.5-2.52.4-2.4-2.3-2.3-2.42.3-2.42.2-2.42.42.42.41.90.0
Incentive Sensitization - Responses3.34.65.52.42.3-2.32.3-2.3-2.12.2-2.2-2.2-2.1-2.12.2-2.32.1-2.32.32.12.22.00.0
Incentive Sensitization - Breakpoint3.24.15.52.32.2-2.22.1-2.2-2.02.1-2.1-2.0-1.9-1.92.1-2.12.0-2.22.11.92.11.90.0
Sum of active levers in priming session hrs 5-60.70.62.0-1.4-1.01.1-1.01.00.7-0.80.80.80.60.7-0.90.3-0.60.7-0.2-0.5-0.8-0.50.0
Progressive ratio0.50.81.31.00.6-0.80.9-0.9-1.10.9-0.9-0.6-1.2-1.00.7-0.91.0-1.10.91.00.90.80.0
Food seeking constrained by brief footshock0.40.40.90.20.5-0.60.7-0.7-0.60.7-0.7-0.9-0.6-0.80.8-0.60.7-0.70.60.60.90.80.0
Seeking ratio, punishment vs. effort0.40.51.0-0.7-0.50.6-0.70.70.9-0.70.80.40.90.7-0.51.0-0.71.0-1.0-0.9-0.8-0.50.0
Retroperitoneal fat weight11.549.185.69.38.7-7.97.6-7.7-7.47.3-7.4-6.5-6.6-6.36.5-7.16.5-6.87.06.77.05.50.0
Reaction time number correct0.00.00.2-0.3-0.20.2-0.10.10.1-0.00.1-0.30.0-0.40.30.30.1-0.2-0.30.10.30.20.0
Reaction time mean minus median0.10.10.5-0.4-0.2-0.10.3-0.2-0.40.4-0.4-0.2-0.6-0.30.3-0.30.6-0.20.30.30.30.70.0
Reaction time mean minus median AUC0.10.20.5-0.3-0.1-0.20.4-0.3-0.50.5-0.5-0.4-0.7-0.40.4-0.40.6-0.30.40.40.40.70.0
Reaction time num false alarms2.02.94.3-2.0-2.11.8-1.71.81.7-1.71.81.21.91.4-1.51.8-1.61.8-2.0-1.7-1.8-1.40.0
Reaction time num false alarms AUC2.23.55.5-2.2-2.32.0-1.92.01.9-1.92.01.52.01.6-1.61.9-1.71.9-2.1-1.8-1.9-1.50.0
Reaction time trials correct on left0.00.00.2-0.3-0.20.2-0.10.10.1-0.00.1-0.30.0-0.40.30.30.1-0.2-0.30.10.30.20.0
Reaction time trials on left0.00.00.1-0.4-0.20.2-0.20.20.1-0.10.1-0.20.1-0.30.20.30.0-0.2-0.40.00.30.10.0
Reaction time mean0.60.91.90.40.6-0.90.9-1.0-1.01.0-1.1-0.7-1.1-0.90.8-1.31.0-1.01.41.11.01.00.0
Reaction time mean AUC0.91.42.90.60.8-1.21.2-1.2-1.21.3-1.3-1.0-1.4-1.11.0-1.51.3-1.21.71.41.31.20.0
Median of all reaction times1.01.43.10.70.9-1.21.2-1.2-1.21.2-1.3-0.9-1.3-1.11.0-1.61.2-1.31.81.41.41.10.0
Reaction time omissions0.40.61.4-0.5-0.30.8-0.80.80.6-0.80.71.10.91.1-1.00.8-0.90.7-0.8-0.9-0.6-1.20.0
Reaction time false alarm rate2.94.15.1-2.0-2.22.1-2.02.12.1-2.12.11.92.22.1-2.01.9-2.02.2-2.1-2.1-2.3-1.90.0
Reaction time premature initiation rate0.00.00.3-0.2-0.60.3-0.10.2-0.1-0.10.1-0.3-0.2-0.2-0.00.20.10.2-0.4-0.1-0.20.20.0
Reaction time premature initiations0.10.10.5-0.5-0.70.4-0.20.3-0.0-0.20.2-0.4-0.2-0.40.10.40.10.0-0.6-0.00.00.20.0
Std. dev. reaction times0.10.20.4-0.00.1-0.30.4-0.4-0.50.5-0.5-0.2-0.6-0.40.3-0.70.6-0.40.70.50.50.50.0
Reaction time trials completed0.00.00.1-0.4-0.20.2-0.20.20.1-0.10.1-0.20.1-0.30.20.30.0-0.2-0.40.00.30.10.0
Reaction time trials AUC0.00.10.3-0.2-0.10.00.0-0.0-0.10.1-0.0-0.4-0.1-0.50.40.20.2-0.3-0.20.20.40.30.0
Run reversals in cocaine runway, females1.11.12.21.31.5-1.21.1-1.2-1.11.0-1.2-0.5-0.8-1.00.9-1.20.8-1.11.31.11.20.30.0
Run reversals in cocaine runway, males2.02.06.5-0.2-0.21.1-1.31.21.1-1.41.22.01.81.9-2.00.6-1.81.2-0.5-1.4-1.3-2.50.0
Latency to leave start box in cocaine runway0.80.91.7-1.1-0.81.0-0.90.91.0-0.90.91.30.91.0-1.10.9-0.91.0-0.9-1.0-0.9-0.80.0
Latency to leave start box in cocaine runway, F0.40.51.1-0.9-0.80.7-0.60.60.8-0.60.61.10.60.8-0.90.6-0.50.7-0.6-0.7-0.6-0.40.0
Latency to leave start box in cocaine runway, M0.20.20.4-0.30.00.4-0.50.40.4-0.50.40.50.40.4-0.50.4-0.50.5-0.3-0.4-0.4-0.70.0
Std. dev. time between licks in bursts0.10.10.50.30.30.0-0.10.1-0.0-0.20.10.70.30.4-0.50.0-0.40.2-0.1-0.2-0.2-0.70.0
Total sessions with >9 infusions1.72.03.91.30.9-1.41.5-1.4-1.31.4-1.3-2.0-1.4-1.91.9-1.21.5-1.21.11.41.11.80.0
Short access day 1 total inactive lever presses0.70.91.41.00.3-1.21.1-1.1-0.91.0-1.0-1.1-0.7-1.01.0-1.00.9-1.01.21.01.00.80.0
Short access day 10 total inactive lever presses0.20.51.60.60.8-0.60.6-0.7-0.80.7-0.80.3-0.5-0.0-0.2-0.90.5-1.11.00.61.3-0.00.0
Short access day 1 total infusions4.05.38.62.01.6-2.32.3-2.3-2.32.3-2.3-2.9-2.3-2.82.7-2.32.4-2.42.32.42.32.40.0
Short access day 10 total infusions1.62.03.81.61.2-1.51.5-1.5-1.31.5-1.3-1.8-1.4-1.82.0-1.11.5-1.21.01.41.01.80.0
Short access total infusions3.03.86.51.61.3-1.92.0-1.9-1.82.0-1.9-2.5-2.0-2.52.5-1.82.1-1.91.72.01.82.40.0
Short access day 1 locomotion1.01.32.61.11.0-1.21.3-1.2-1.11.2-1.1-1.6-1.1-1.31.4-0.91.3-0.81.00.90.71.60.0
Short access day 10 total locomotion1.22.23.61.91.4-1.71.7-1.7-1.51.6-1.6-1.3-1.5-1.31.4-1.41.5-1.41.41.41.51.50.0
Short access total locomotion1.51.82.51.51.1-1.51.5-1.5-1.31.4-1.3-1.4-1.3-1.51.5-1.31.4-1.21.21.31.21.60.0
One hour access (0.3 mA shock)3.43.95.62.41.9-2.22.2-2.1-2.12.1-2.1-1.8-2.0-2.12.1-2.02.0-1.82.02.01.92.00.0
Compulsive drug intake3.54.25.8-1.7-2.22.1-2.12.12.2-2.12.12.42.12.2-2.41.8-2.22.0-1.7-2.0-1.9-2.40.0
One hour access (shock baseline)5.17.810.52.82.7-2.93.0-2.9-2.92.9-2.8-2.9-2.9-3.23.2-2.63.0-2.52.52.82.43.20.0
Social response proportion2.32.64.0-1.7-1.91.8-1.81.71.7-1.71.61.91.61.9-2.01.2-1.71.1-1.3-1.6-1.0-2.00.0
Social responses0.20.20.8-0.4-0.70.10.2-0.2-0.40.3-0.3-0.3-0.6-0.40.2-0.40.7-0.80.20.40.90.80.0
Social time2.43.37.2-2.5-2.72.0-1.91.92.1-1.81.91.61.81.8-1.71.8-1.61.6-1.8-1.7-1.6-1.20.0
Soleus weight1.13.26.6-0.9-0.41.4-1.71.61.8-1.81.72.02.32.3-2.21.7-2.21.9-1.4-1.9-1.8-2.60.0
Bone: stiffness0.71.11.61.21.0-1.01.2-1.1-1.31.1-1.2-0.9-1.1-1.00.9-1.21.2-1.21.01.01.21.00.0
Tibialis anterior weight1.86.07.6-2.2-1.92.6-2.62.62.5-2.62.52.22.82.6-2.62.5-2.62.4-2.4-2.5-2.5-2.70.0
Time to tail flick, vehicle, before self-admin0.70.71.90.40.4-0.80.9-0.9-0.80.9-0.9-0.9-1.0-0.80.9-0.81.0-0.60.90.80.71.40.0
Time to tail flick, vehicle, after self-admin2.93.86.02.22.0-2.22.1-2.1-1.92.0-1.9-2.5-1.8-2.02.2-1.82.0-1.41.92.01.62.20.0
Time to tail flick, test, before self-admin1.51.53.01.11.7-1.31.3-1.3-1.31.3-1.3-1.3-1.3-1.21.3-1.11.3-1.11.21.21.11.40.0
Time to tail flick, test, after self-admin2.72.83.51.21.7-1.71.8-1.8-1.51.8-1.7-1.9-1.5-1.61.6-1.91.8-1.81.81.61.81.90.0
Delta time to tail flick, vehicle, before/after SA0.40.41.51.21.1-0.80.6-0.7-0.50.6-0.6-0.7-0.2-0.40.5-0.70.3-0.40.70.50.40.10.0
Delta time to tail flick, test, before/after SA0.10.10.5-0.4-0.70.2-0.20.20.4-0.20.3-0.10.30.10.00.1-0.10.1-0.2-0.3-0.00.10.0
Tibia length0.00.10.4-0.60.10.1-0.00.1-0.30.1-0.1-0.5-0.6-0.50.1-0.40.2-0.10.30.40.20.20.0
Ambulatory time before self-admin0.00.00.40.50.70.0-0.00.0-0.1-0.0-0.0-0.20.0-0.0-0.10.1-0.00.1-0.2-0.0-0.2-0.10.0
Ambulatory time after self-admin1.31.62.91.21.3-1.01.2-1.1-1.71.2-1.3-1.4-1.7-1.51.2-1.01.5-1.01.01.40.81.40.0
Bone: tissue strength0.40.40.8-0.6-0.90.7-0.60.60.6-0.60.60.60.50.8-0.70.6-0.50.5-0.7-0.7-0.4-0.50.0
Total heroin consumption0.30.30.7-0.8-0.40.6-0.60.60.5-0.60.50.80.60.8-0.80.0-0.60.40.0-0.5-0.6-0.70.0
Bone: trabecular number0.30.51.41.20.9-0.90.8-0.8-0.70.8-0.7-0.8-0.5-0.60.8-0.50.6-0.50.60.60.40.60.0
Bone: trabecular spacing0.10.20.4-0.1-0.1-0.10.3-0.3-0.40.4-0.3-0.3-0.6-0.50.4-0.30.5-0.60.30.40.60.60.0
Bone: trabecular thickness0.40.50.90.80.9-0.90.8-0.8-0.70.8-0.8-0.8-0.5-0.80.7-0.80.7-0.60.70.80.50.60.0
Bone: trabecular tissue density0.60.92.4-0.9-0.50.9-0.90.90.9-0.90.81.61.11.1-1.30.3-1.00.9-0.4-0.8-0.8-1.30.0
Water consumed over 24 hours0.91.11.61.31.3-1.11.1-1.1-1.21.1-1.1-0.9-1.1-1.11.0-1.11.0-1.11.01.11.10.90.0
Number of responses in last shaping day4.54.96.22.51.8-2.42.4-2.3-2.42.3-2.3-2.4-2.3-2.52.3-2.12.2-2.22.22.32.22.10.0