Hub : Genes

Cxcl6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	PL	gene expression	Cxcl6	0.03	0.02	1.3e-03	0.02	0.03	0.03	0.01	2.6e-03	3.1e-04	6.9e-04	1.3e-02
2	Brain	gene expression	Cxcl6	0.06	0.03	4.5e-05	0.03	0.05	0.05	0.02	7.0e-04	3.1e-05	2.2e-05	6.7e-03
3	pVTA	gene expression	Cxcl6	0.11	0.06	1.4e-04	0.14	0.1	0.12	0.07	1.3e-06	3.4e-05	7.1e-06	7.5e-04
4	Liver	gene expression	Cxcl6	0.04	0.03	3.6e-03	0.02	0.01	0.01	0.01	3.4e-03	7.9e-03	3.3e-02	3.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	1.2	2.1	3.2	1.7	-0.2	-1.4	-1.8
Area under the delay curve	0.7	0.8	1.8	-0.5	0.3	1.0	1.4
BMI with tail	1.0	3.1	6.9	2.6	1.2	-1.7	-1.1
BMI without tail	0.2	0.5	0.7	0.8	0.3	-0.6	-0.8
Body weight	0.5	2.1	4.1	0.6	2.0	-1.0	-1.7
Weight adjusted by age	0.7	0.8	2.0	0.5	-0.6	-0.9	-1.4
Bone surface	1.4	2.4	5.1	1.3	0.4	-1.6	-2.3
Bone volume	1.2	2.0	3.4	1.5	0.2	-1.6	-1.8
Breakpoint value in progressive ratio session	0.2	0.2	0.6	0.2	0.5	-0.7	0.4
Number of licking bursts	0.1	0.1	0.2	-0.5	-0.3	0.2	-0.0
Context. condit. distance diff. score	0.8	1.0	2.6	0.5	1.6	0.6	0.9
Locomotion velocity, session 1	0.5	0.6	1.3	0.9	1.1	-0.2	0.5
Locomotion distance, session 1	0.6	0.7	1.9	0.6	1.4	0.2	0.8
Locomotion velocity, session 2	0.8	1.0	2.3	1.1	1.5	-0.4	-0.3
Locomotion distance, session 2	0.8	1.2	2.6	-0.1	1.2	0.7	1.6
Locomotion velocity, session 3	0.1	0.1	0.5	0.3	0.7	0.2	-0.0
Locomotion distance, session 3	0.6	0.6	1.2	1.1	1.0	-0.5	0.1
Stereotopy head waving bouts, day 3	0.2	0.3	0.9	-0.3	0.1	0.4	0.9
Stereotopy head waving duration, day 3	0.4	0.5	0.8	-0.8	-0.6	0.9	0.5
Locomotion velocity, session 7	0.3	0.3	0.5	-0.4	-0.1	0.6	0.7
Locomotion distance, session 7	0.3	0.4	1.1	-0.3	-1.0	0.3	0.4
Stereotopy head waving bouts, day 7	1.0	1.2	2.7	1.0	1.7	-0.9	-0.1
Stereotopy head waving duration, day 7	0.4	0.5	1.7	0.3	1.3	-0.2	0.4
Locomotion velocity, session 8	0.5	0.6	1.0	0.7	0.5	0.8	1.0
Locomotion distance, session 8	0.9	1.3	2.5	0.9	1.6	0.6	1.3
Degree of sensitization distance	0.8	0.8	1.7	-1.1	-1.3	0.7	0.1
Degree of sensitization stereotypy	0.8	0.8	2.7	0.6	1.6	-0.5	0.2
Conditioned locomotion	1.4	1.7	4.0	-1.2	-2.0	1.1	0.4
Cocaine response after cond. corrected	0.4	0.4	1.2	-0.7	-1.1	0.2	0.1
Cocaine response after cond. not corrected	0.5	0.6	1.0	0.3	-0.9	-0.6	-1.0
Cocaine response before conditioning	2.3	2.7	5.0	1.8	0.4	-1.6	-2.2
Saline control response	0.2	0.3	0.6	0.8	0.3	-0.8	-0.2
Bone: connectivity density	0.9	1.3	2.9	1.2	-0.5	-0.8	-1.7
Bone: cortical apparent density	0.2	0.3	0.6	0.5	0.3	-0.3	0.8
Bone: cortical area	0.8	1.2	2.3	1.3	-0.2	-1.5	-1.0
Bone: cortical porosity	0.6	0.6	1.8	-0.7	-1.3	0.3	0.3
Bone: cortical porosity	0.4	0.5	1.6	-0.5	-1.3	0.2	0.0
Bone: cortical thickness	1.4	2.3	4.6	2.1	-0.5	-2.0	-0.8
Bone: cortical thickness	0.8	1.0	2.1	1.0	-0.6	-1.5	-0.6
Bone: cortical tissue density	0.2	0.3	0.6	0.5	0.4	-0.3	0.8
Condit. Reinf. active minus inactive responses	0.4	0.4	1.5	0.1	1.2	-0.1	0.2
Condit. Reinf. active-inactive response ratio	0.6	0.6	1.5	-0.1	1.2	-0.1	0.9
Condit. Reinf. active responses	0.4	0.4	1.5	0.3	1.2	-0.2	0.3
Condit. Reinf. inactive responses	0.3	0.3	0.5	0.7	0.5	-0.4	-0.7
Incentive salience index mean	0.1	0.1	0.3	0.1	0.5	0.2	0.3
Condit. Reinf. lever presses	0.0	0.1	0.1	0.3	-0.3	-0.1	-0.1
Condit. Reinf. active minus inactive responses	1.1	1.3	3.1	1.2	1.8	-0.9	-0.3
Condit. Reinf. active-inactive response ratio	1.4	1.5	2.9	0.8	0.7	-1.3	-1.7
Condit. Reinf. active responses	1.1	1.5	5.2	0.8	2.3	-0.5	0.2
Condit. Reinf. inactive responses	0.6	0.7	1.4	-0.0	1.1	0.5	1.2
Condit. Reinf. lever presses	0.3	0.4	0.6	-0.8	0.6	0.6	-0.7
Condit. Reinf. lever reinforcers received	1.0	1.4	5.0	0.7	2.2	-0.4	0.3
Conditioned reinforcement - actives	0.6	0.6	2.0	-0.4	0.0	0.4	1.4
Conditioned reinforcement - inactives	0.8	0.9	2.0	-0.3	-1.4	-0.6	-1.2
Conditioned locomotion	1.0	1.1	3.1	-1.7	-0.8	0.8	0.4
Patch foraging indifference point 0 sec	0.1	0.1	0.3	0.2	0.6	0.3	0.0
Patch foraging indifference point AUC	1.8	2.0	5.0	-1.3	-2.2	1.0	-0.7
Delay disc. indifference point, 0s delay	0.4	0.5	1.1	0.4	1.1	-0.3	0.7
Delay disc. indifference point, 16s delay	0.8	0.8	2.3	-0.1	0.6	0.8	1.5
Delay disc. indifference point, 2s delay	0.7	0.7	1.0	-1.0	0.4	1.0	0.9
Delay disc. indifference point, 24s delay	1.4	1.4	2.3	-1.3	-0.4	1.5	1.2
Delay disc. indifference point, 4s delay	1.6	1.6	4.3	-0.6	-0.1	1.4	2.1
Delay disc. indifference point, 8s delay	0.2	0.2	0.8	0.2	-0.3	0.1	0.9
Indifference point function ln k	1.6	2.2	5.3	1.4	2.3	-1.1	0.7
Indifference point function log k	1.6	2.2	5.3	1.4	2.3	-1.1	0.7
Patch foraging total patch changes 0 sec	0.0	0.1	0.2	0.1	0.1	0.5	0.3
Patch foraging total patch changes 12 sec	1.2	1.6	2.1	-0.9	-1.1	1.5	1.5
Patch foraging total patch changes 18 sec	0.1	0.1	0.2	0.1	0.5	-0.4	-0.2
Patch foraging total patch changes 24 sec	0.6	0.8	1.4	-0.8	-0.2	0.9	1.2
Patch foraging total patch changes 6 sec	1.1	1.7	2.6	-1.1	-1.6	1.6	0.6
Patch foraging time to switch 0 sec	0.4	0.6	1.4	1.2	0.7	-0.8	-0.0
Patch foraging water rate 0 sec	0.6	1.0	1.9	-1.3	-1.4	0.8	-0.1
Patch foraging water rate 12 sec	0.6	0.9	1.4	-1.0	-1.2	0.9	0.5
Patch foraging water rate 18 sec	0.5	0.7	2.6	-0.3	1.6	0.1	0.2
Patch foraging water rate 24 sec	0.1	0.1	0.2	-0.3	0.4	-0.4	0.1
Patch foraging water rate 6 sec	1.0	1.5	2.6	-1.6	-0.1	1.4	1.3
Seeking ratio, delayed vs. immediate footshock	1.0	1.2	2.4	-1.1	-0.1	1.1	1.6
Distance traveled before self-admin	1.5	1.6	3.7	-1.9	-0.2	1.0	1.3
Distance traveled after self-admin	3.0	3.4	7.9	-2.0	0.3	1.2	2.8
Extensor digitorum longus weight	3.8	14.8	30.4	5.5	1.1	-4.3	-3.1
Bone: elastic displacement	1.9	2.2	4.1	2.0	0.2	-1.8	-1.2
Bone: elastic work	2.2	2.9	4.8	2.2	-0.3	-2.2	-1.4
Bone: endosteal estimation	0.1	0.3	1.0	-1.0	0.5	0.1	0.2
Bone: endosteal perimeter	0.2	0.4	1.2	-0.4	0.4	-0.3	-1.1
Epididymis fat weight	0.5	1.2	3.3	-0.9	-0.1	0.7	1.8
Delta time in closed arm before/after self-admin	0.1	0.1	0.2	0.1	0.4	0.3	-0.2
Delta time in open arm before/after self-admin	1.7	1.7	2.2	-1.4	-1.5	1.3	0.9
Diff in mean of infusions in LGA sessions	1.4	1.6	3.6	0.8	1.9	-1.3	-0.7
Delay discount exponential model param	0.9	0.9	1.9	0.7	-0.0	-1.2	-1.4
Extinction: sum of active levers before priming	1.5	1.5	3.0	-1.6	-0.2	1.7	0.6
Active lever presses in extinction session 6	1.1	1.0	3.6	-0.6	1.9	-0.2	-0.3
Bone: final force	0.1	0.1	0.4	-0.1	0.0	-0.6	-0.3
Bone: final moment	0.1	0.1	0.2	-0.3	0.1	-0.5	-0.1
Food consumed during 24 hour testing period	0.1	0.1	0.3	0.3	-0.6	-0.1	-0.4
Glucose	1.4	2.0	4.4	-0.8	2.1	0.6	1.7
Heart weight	0.2	0.2	0.9	-0.2	-0.2	0.0	-0.9
Delay discount hyperbolic model param	1.1	1.1	2.2	0.8	0.0	-1.3	-1.5
Intermittent access intake day 1-15 change	0.5	0.5	1.0	0.7	1.0	-0.5	0.4
Intermittent access intake escalation	0.4	0.4	1.0	0.4	1.0	-0.3	0.6
Intermittent access intake escalation 2	0.2	0.2	0.6	-0.8	0.0	0.3	0.3
Intermitt. access day 1 inactive lever presses	0.5	0.6	1.9	1.4	-0.5	-0.4	0.0
Intermitt. access day 15 inactive lever presses	1.3	1.5	3.5	0.4	-1.0	-1.1	-1.9
Intermitt. access escalation Index	2.1	1.9	4.3	0.7	2.1	-1.6	-0.1
Intermittent access day 1 total infusions	1.0	1.2	2.7	-1.6	-0.2	1.4	-0.1
Intermittent access day 15 total infusions	0.7	0.8	1.6	-1.3	-0.0	1.2	0.4
Intermittent access terminal intake (last 3 days)	1.6	1.8	4.3	-2.1	-0.3	1.6	0.5
Intermittent access total infusions	1.3	1.4	3.3	-1.8	-0.4	1.5	0.2
Intermittent access day 1 locomotion	0.4	0.4	0.9	-0.9	0.3	0.9	-0.1
Intermittent access day 15 total locomotion	2.8	3.1	5.8	-1.9	-0.3	2.4	1.7
Intermittent access total locomotion	1.5	1.7	2.5	-1.5	0.7	1.6	1.2
Intermittent access standard deviation	0.5	0.5	0.9	-0.5	-0.9	1.0	0.1
Left kidney weight	0.6	1.6	2.4	-1.6	-0.6	1.3	-1.4
Right kidney weight	0.8	2.3	4.6	-2.1	-1.1	1.5	-1.0
Cocaine induced anxiety	0.9	1.0	3.1	0.9	-0.2	-1.8	-0.5
Post-drug Anxiety	0.1	0.1	0.2	0.0	0.3	-0.4	0.4
Baseline Anxiety	2.6	2.7	6.6	-1.1	0.7	1.6	2.6
Tail length	0.3	0.8	2.9	-1.7	0.4	0.5	-0.1
Length with tail	0.6	2.4	6.7	-2.6	1.0	1.4	-0.1
Length without tail	0.6	1.3	2.5	-1.6	0.7	1.3	0.6
Times rat made contact with spout	2.1	2.4	7.1	-1.1	-2.7	0.9	-0.7
Lifetime Intake	1.1	1.3	3.2	-1.8	-0.6	1.3	-0.0
Liver weight, left	0.9	1.5	3.5	-1.2	-0.5	0.9	1.9
Liver weight, right	1.9	3.1	5.8	-2.0	-0.8	1.5	2.4
Locomotor activity	0.2	0.3	0.3	-0.6	-0.6	0.6	-0.1
Locomotor testing distance	0.1	0.1	0.3	-0.1	-0.1	0.5	0.4
Locomotor testing rearing	0.1	0.2	0.4	0.4	0.7	0.1	-0.0
Locomotion in novel chamber	0.4	0.5	1.0	-0.5	-0.1	1.0	1.0
Locomotion in novel chamber post-restriction	0.9	1.1	2.8	-0.9	-0.7	1.7	-0.4
Fecal boli incidents, locomotor time 1	1.4	1.5	5.2	-0.3	-2.3	-0.7	-0.5
Change in fecal boli incidents, locomotor task	1.2	1.1	4.2	0.4	2.1	-0.3	0.1
Time >=10cm from walls, locomotor time 1	1.1	1.1	3.1	0.5	0.0	-1.1	-1.8
Bouts of movement, locomotor time 1	0.3	0.4	0.7	-0.8	-0.1	0.7	0.5
Total resting periods, locomotor time 1	0.7	0.7	1.2	-1.1	-0.4	0.7	1.0
Rest time, locomotor task time 1	0.5	0.6	1.4	-0.8	-0.4	0.2	1.2
Distance moved, locomotor task time 1	0.1	0.1	0.5	-0.1	0.2	0.2	-0.7
Vertical activity count, locomotor time 1	0.6	0.6	1.4	-0.6	0.8	1.2	0.2
Time >=10cm from walls, locomotor time 2	0.7	0.8	1.2	1.0	-0.3	-1.1	-0.9
Bouts of movement, locomotor time 2	1.3	1.4	3.6	-0.9	0.3	1.9	1.1
Total resting periods, locomotor time 2	1.1	1.2	2.8	-0.9	0.2	1.7	1.0
Rest time, locomotor task time 2	2.7	3.1	5.4	-1.8	-2.3	1.4	1.3
Distance moved, locomotor task time 2	2.3	2.7	4.5	1.6	2.1	-1.4	-1.4
Vertical activity count, locomotor time 2	2.3	2.5	8.8	1.0	3.0	-0.5	-0.0
Light reinforcement 1	0.5	1.0	2.0	-0.7	-0.8	0.9	-1.4
Light reinforcement 2	1.6	2.1	4.5	-1.2	-2.1	1.3	-1.0
Bone: marrow area	0.1	0.3	0.8	-0.9	0.5	0.0	0.2
Bone: maximum diameter	0.7	1.3	2.5	0.8	0.1	-1.4	-1.6
Bone: maximum force	0.1	0.2	0.3	-0.2	-0.6	-0.4	-0.5
Bone: maximum moment	0.1	0.1	0.3	-0.4	-0.5	-0.2	-0.2
Mean time between licks in bursts	0.1	0.2	0.6	-0.8	0.1	0.2	-0.2
Mean num. licks in bursts	0.6	0.7	2.0	-0.6	-1.4	0.6	-0.1
Cd content in liver	0.5	0.6	1.6	0.0	-0.4	-0.7	-1.3
Co content in liver	0.2	0.2	0.5	-0.7	-0.2	0.6	0.3
Cu content in liver	1.2	1.4	4.2	-0.7	-2.0	0.9	0.6
Fe content in liver	1.2	1.4	2.2	1.3	0.5	-1.2	-1.5
K content in liver	3.7	3.7	4.7	-1.5	-2.2	2.0	2.0
Mg content in liver	4.3	4.4	8.9	-2.0	-3.0	2.0	1.0
Mn content in liver	1.1	1.2	2.2	1.5	1.1	-1.0	0.6
Na content in liver	3.6	3.8	5.1	-1.5	-2.3	2.2	1.6
Rb content in liver	0.3	0.3	0.9	0.2	0.9	-0.6	-0.0
Se content in liver	0.8	0.9	2.5	-0.7	-0.8	1.6	0.3
Sr content in liver	1.7	1.5	3.6	0.9	-0.2	-1.3	-1.9
Zn content in liver	0.2	0.3	0.6	-0.1	-0.3	0.6	0.8
Bone: minimum diameter	0.7	1.3	4.4	-2.1	-0.3	0.7	0.0
Time in familiar zone, hab. session 1	0.6	0.5	1.3	0.0	-1.1	0.6	0.7
Time in novel zone, hab. session 1	0.9	0.9	2.0	-1.2	1.4	0.2	0.1
Total zone transitions, hab. session 1	1.2	1.7	2.7	-0.6	1.0	1.6	1.6
Total locomotion distance, hab. session 1	2.5	3.5	6.3	-1.8	-0.9	2.5	1.9
Locomotion velocity, hab. session 1	1.7	2.4	4.7	-1.2	-0.9	2.2	1.6
Time in familiar zone, hab. session 2	2.0	2.0	5.4	-1.1	-2.3	1.0	-0.6
Time in novel zone, hab. session 2	2.6	2.6	8.0	0.9	2.8	-1.0	0.9
Total zone transitions, hab. session 2	0.4	0.5	1.3	0.2	1.1	0.3	0.6
Total locomotion distance, hab. session 2	0.5	0.6	1.1	-0.7	0.4	1.1	0.9
Locomotion velocity, hab. session 2	0.7	0.9	1.8	-0.8	0.2	1.4	1.1
Novel to familiar place preference ratio	0.2	0.2	0.3	-0.5	-0.1	0.6	0.2
Novelty place preference	0.4	0.4	0.6	-0.8	-0.4	0.8	0.1
Time in novel zone, NPP test	0.4	0.5	0.9	-0.9	-0.1	0.9	0.4
Total zone transitions, NPP test	1.1	1.5	2.7	1.7	1.5	-1.0	0.1
Total locomotion distance, NPP test	0.1	0.1	0.3	0.0	-0.2	0.6	0.2
Locomotion velocity, NPP test	0.1	0.1	0.4	0.6	0.0	0.1	-0.2
Intraocular pressure	0.3	0.4	0.7	-0.9	-0.0	0.4	-0.7
Delta distance traveled before/after self-admin	0.8	0.9	2.3	0.3	1.1	-0.0	1.5
Delta ambulatory time before/after self-admin	1.4	1.5	2.7	0.8	1.5	-0.6	1.7
Parametrial fat weight	0.2	0.3	0.5	0.1	0.6	-0.7	-0.7
Pavlov. Cond. lever latency	0.5	0.6	1.6	0.4	-0.0	-0.8	-1.3
Pavlov. Cond. magazine entry latency	0.5	0.7	1.2	-0.6	0.5	1.1	0.9
Pavlov. Cond. change in total contacts	0.4	0.4	1.3	0.0	0.6	0.2	1.1
Pavlov. Cond. index score	0.7	0.9	2.6	-0.2	0.4	0.8	1.6
Pavlov. Cond. latency score	0.5	0.6	1.9	-0.2	0.2	0.6	1.4
Pavlov. Cond. lever contacts	0.6	0.7	2.0	0.2	0.9	0.3	1.4
Pavlov. Cond. magazine entry number	0.5	0.7	1.2	0.0	-1.0	-0.6	-1.1
Pavlov. Cond. intertrial magazine entries	0.2	0.3	0.8	-0.1	0.0	0.4	0.9
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.9	2.7	-0.2	0.5	0.8	1.6
Pavlov. Cond. response bias	0.8	0.9	2.2	-0.4	0.8	0.8	1.5
Pavlov. Cond. lever latency	0.6	0.8	1.9	0.7	0.7	-0.6	1.4
Pavlov. Cond. magazine entry latency	0.3	0.4	1.0	-0.4	-0.4	0.2	-1.0
Pavlov. Cond. change in total contacts	0.8	1.0	2.4	-0.8	-1.6	0.8	-0.7
Pavlov. Cond. index score	0.7	0.9	2.2	-0.7	-1.0	0.3	-1.5
Pavlov. Cond. latency score	0.7	0.8	2.3	-0.3	-1.0	-0.0	-1.5
Pavlov. Cond. lever contacts	1.1	1.6	2.3	-1.2	-1.5	0.9	-1.2
Pavlov. Cond. magazine entry number	0.2	0.2	0.8	0.2	0.4	0.1	0.9
Pavlov. Cond. intertrial magazine entries	0.1	0.2	0.6	0.2	0.8	-0.2	-0.1
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.9	2.0	-0.7	-1.1	0.4	-1.4
Pavlov. Cond. response bias	0.8	1.1	1.6	-1.3	-1.0	1.0	-0.9
Time in closed arm before self-admin	0.9	1.0	1.4	1.2	0.8	-0.8	-1.0
Time in closed arm after self-admin	1.1	1.1	2.0	1.4	1.3	-0.4	-0.8
Time in open arm before self-admin	0.5	0.6	1.5	0.3	1.2	-0.8	-0.3
Time in open arm after self-admin	2.5	2.8	5.1	-2.3	-1.7	1.6	0.8
Bone: periosteal estimation	0.2	0.4	1.0	0.2	0.2	-1.0	-0.7
Bone: periosteal perimeter	0.2	0.3	0.8	0.2	-0.3	-0.6	-0.9
Bone: post-yield work	1.5	2.1	5.0	-2.2	-1.2	1.4	0.3
Progressive ratio test 1 active lever presses	3.1	3.2	7.8	-2.8	-0.9	2.1	0.1
Progressive ratio test 1 breakpoint	2.7	2.9	6.8	-2.6	-0.8	2.0	0.1
Progressive ratio test 1 inactive lever presses	0.8	0.8	1.9	-0.8	-1.4	0.9	0.1
Progressive ratio test 2 active lever presses	2.2	2.3	5.4	-2.3	-1.2	1.5	0.5
Progressive ratio test 2 breakpoint	1.5	1.7	3.7	-1.9	-1.1	1.3	0.4
Progressive ratio test 2 inactive lever presses	1.0	1.2	2.5	-1.3	-1.6	0.8	0.2
Incentive Sensitization - Responses	0.2	0.2	0.6	-0.8	0.3	-0.2	0.1
Incentive Sensitization - Breakpoint	0.2	0.2	0.8	-0.9	0.2	-0.2	0.1
Sum of active levers in priming session hrs 5-6	0.3	0.3	0.6	-0.6	-0.8	0.3	0.1
Progressive ratio	0.5	0.6	1.1	0.8	-0.7	-1.0	-0.3
Food seeking constrained by brief footshock	0.3	0.4	0.6	0.8	0.6	-0.6	-0.6
Seeking ratio, punishment vs. effort	0.2	0.3	0.5	-0.6	0.2	0.7	0.4
Retroperitoneal fat weight	0.4	1.3	4.2	-0.7	2.0	0.6	0.6
Reaction time number correct	0.6	0.9	3.1	0.1	1.8	-0.4	-0.5
Reaction time mean minus median	0.2	0.3	0.7	-0.7	-0.3	-0.1	-0.8
Reaction time mean minus median AUC	0.3	0.4	0.7	-0.9	-0.7	-0.1	-0.7
Reaction time num false alarms	1.3	1.7	4.1	-0.8	-0.2	1.5	2.0
Reaction time num false alarms AUC	1.3	1.9	4.3	-0.8	0.2	1.5	2.1
Reaction time trials correct on left	0.6	0.9	3.1	0.1	1.8	-0.4	-0.5
Reaction time trials on left	0.7	1.0	3.4	0.1	1.8	-0.5	-0.5
Reaction time mean	0.2	0.2	0.5	0.1	0.4	-0.7	-0.5
Reaction time mean AUC	0.1	0.1	0.4	-0.1	0.6	-0.4	-0.1
Median of all reaction times	0.2	0.2	0.6	0.2	0.7	-0.6	-0.2
Reaction time omissions	1.4	1.9	3.1	1.4	1.4	-1.8	-0.6
Reaction time false alarm rate	1.6	2.2	4.1	-0.9	-0.8	1.8	2.0
Reaction time premature initiation rate	0.1	0.1	0.1	-0.3	-0.4	0.4	0.3
Reaction time premature initiations	0.1	0.1	0.2	-0.3	0.5	0.1	-0.0
Std. dev. reaction times	0.1	0.1	0.2	-0.2	0.2	-0.5	-0.3
Reaction time trials completed	0.7	1.0	3.4	0.1	1.8	-0.5	-0.5
Reaction time trials AUC	0.9	1.3	4.4	0.1	2.1	-0.6	-0.5
Run reversals in cocaine runway, females	0.3	0.3	0.4	0.5	0.6	-0.6	0.2
Run reversals in cocaine runway, males	1.3	1.2	1.9	0.9	1.3	-0.8	-1.4
Latency to leave start box in cocaine runway	0.4	0.5	1.1	-0.5	1.0	0.7	-0.3
Latency to leave start box in cocaine runway, F	0.6	0.7	1.6	-1.1	0.1	1.2	-0.2
Latency to leave start box in cocaine runway, M	1.4	1.3	3.0	0.7	1.7	-1.1	-0.8
Std. dev. time between licks in bursts	0.3	0.3	0.7	-0.8	-0.2	0.6	0.5
Total sessions with >9 infusions	0.3	0.3	0.9	-0.2	0.2	-0.3	-0.9
Short access day 1 total inactive lever presses	0.1	0.1	0.4	-0.2	-0.6	0.2	0.1
Short access day 10 total inactive lever presses	0.8	0.9	2.4	1.6	-0.7	-0.6	-0.3
Short access day 1 total infusions	1.0	1.0	1.7	-1.3	-1.1	1.1	-0.4
Short access day 10 total infusions	0.9	1.0	2.3	-1.5	-0.5	1.2	-0.4
Short access total infusions	0.3	0.3	1.0	-1.0	-0.2	0.3	-0.4
Short access day 1 locomotion	1.5	1.6	2.7	-1.6	0.1	1.6	1.1
Short access day 10 total locomotion	0.4	0.4	0.9	-0.4	-0.0	0.8	0.9
Short access total locomotion	0.2	0.2	0.4	-0.6	0.0	0.5	0.7
One hour access (0.3 mA shock)	1.8	2.1	4.5	-2.1	-0.1	1.8	0.9
Compulsive drug intake	1.0	1.0	2.9	1.7	-0.2	-1.0	-0.2
One hour access (shock baseline)	2.8	3.3	8.0	-2.8	-0.8	2.0	0.7
Social response proportion	1.1	1.2	3.2	-0.8	-1.8	0.3	1.0
Social responses	0.2	0.3	0.7	-0.4	0.1	0.8	0.6
Social time	0.1	0.2	0.4	-0.3	-0.6	0.2	0.4
Soleus weight	0.8	2.4	6.7	2.6	0.7	-1.2	0.9
Bone: stiffness	0.8	1.3	2.2	-1.5	-0.5	1.3	1.0
Tibialis anterior weight	0.7	2.4	6.4	2.5	-0.2	-1.5	-1.0
Time to tail flick, vehicle, before self-admin	0.4	0.4	1.0	-1.0	-0.6	0.5	0.0
Time to tail flick, vehicle, after self-admin	0.5	0.5	1.3	0.3	1.1	0.1	0.9
Time to tail flick, test, before self-admin	0.1	0.1	0.4	0.4	0.1	-0.0	0.6
Time to tail flick, test, after self-admin	2.3	2.4	7.7	-0.9	2.8	0.9	-0.4
Delta time to tail flick, vehicle, before/after SA	0.7	0.7	1.8	0.8	1.3	-0.3	0.5
Delta time to tail flick, test, before/after SA	0.9	0.8	1.3	-1.1	0.9	0.8	-0.7
Tibia length	0.3	0.9	1.7	0.1	1.3	-1.3	0.3
Ambulatory time before self-admin	1.8	1.9	3.7	-1.9	0.8	1.3	1.2
Ambulatory time after self-admin	3.5	3.8	8.6	-1.6	1.6	1.2	2.9
Bone: tissue strength	0.7	0.7	1.3	-1.1	-0.4	1.1	0.5
Total heroin consumption	1.7	2.0	4.9	-0.7	2.2	0.2	1.6
Bone: trabecular number	0.4	0.6	1.1	1.0	-0.3	-0.7	-0.9
Bone: trabecular spacing	0.5	0.7	1.6	-0.6	-0.7	0.6	1.3
Bone: trabecular thickness	1.4	1.7	4.1	1.2	-0.4	-0.9	-2.0
Bone: trabecular tissue density	0.1	0.1	0.3	0.6	0.2	-0.5	-0.1
Water consumed over 24 hours	0.4	0.5	0.8	-0.9	-0.6	0.8	-0.5
Number of responses in last shaping day	1.1	1.1	2.8	-0.7	-0.8	1.7	0.6