Hub : Genes

Cul7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Cul7 0.27 0.15 1.3e-04 0.16 0.17 0.17 0.17 1.1e-04 8.5e-05 9.4e-05 9.2e-05
2 PL mRNA stability Cul7 0.02 0.02 3.6e-03 0.03 0.03 0.01 0.02 8.9e-04 6.6e-04 1.3e-02 1.3e-03
3 BLA gene expression Cul7 0.08 0.06 1.4e-03 0.04 0.04 0.03 0.04 5.1e-03 4.9e-03 8.3e-03 2.9e-03
4 NAcc gene expression Cul7 0.11 0.09 3.2e-13 0.1 0.09 0.09 0.09 1.4e-14 1.1e-13 7.5e-14 4.5e-14
5 Brain mRNA stability Cul7 0.15 0.08 2.4e-14 0.16 0.16 0.16 0.16 8.2e-15 1.2e-14 8.3e-15 1.8e-14
6 NAcc mRNA stability Cul7 0.02 0.02 3.3e-04 0.02 0.01 0.01 0.01 1.2e-03 3.1e-03 1.4e-02 4.1e-03
7 PL gene expression Cul7 0.16 0.1 0.0e+00 0.18 0.17 0.17 0.17 7.4e-19 1.0e-18 1.3e-18 1.1e-18
8 Brain gene expression Cul7 0.39 0.14 0.0e+00 0.42 0.42 0.42 0.43 6.5e-43 2.0e-42 8.9e-43 6.2e-43
9 IL gene expression Cul7 0.25 0.13 5.3e-05 0.18 0.14 0.14 0.16 5.1e-05 3.4e-04 2.9e-04 9.8e-05
10 pVTA gene expression Cul7 0.04 0.04 2.7e-03 0.03 0.03 0.02 0.03 1.6e-03 3.5e-03 5.7e-03 3.1e-03
11 LHb gene expression Cul7 0.4 0.16 1.2e-07 0.23 0.18 0.14 0.23 3.6e-06 5.8e-05 3.0e-04 4.0e-06
12 Liver gene expression Cul7 0.08 0.06 1.7e-05 0.03 0.03 0.03 0.03 1.5e-04 2.9e-04 1.6e-04 1.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.81.33.3-1.31.2-1.7-0.91.00.9-0.9-0.8-0.9-0.9-0.91.8
Area under the delay curve7.18.310.7-2.82.9-1.8-3.33.13.3-3.1-3.3-3.0-3.0-3.01.2
BMI with tail3.913.315.23.9-3.83.73.7-3.7-3.73.53.63.63.63.6-3.5
BMI without tail5.215.816.94.1-4.13.74.1-4.1-4.13.94.14.04.04.0-3.2
Body weight4.519.521.84.6-4.63.94.6-4.6-4.74.54.64.54.54.5-3.3
Weight adjusted by age0.30.40.80.7-0.80.60.6-0.7-0.60.90.70.70.70.7-0.3
Bone surface1.73.15.2-2.01.9-2.3-1.61.61.6-1.7-1.5-1.6-1.6-1.62.2
Bone volume0.91.62.9-1.41.4-1.7-1.11.11.1-1.1-1.0-1.1-1.1-1.11.7
Breakpoint value in progressive ratio session0.10.10.20.1-0.00.5-0.00.20.0-0.3-0.2-0.2-0.2-0.2-0.5
Number of licking bursts2.54.15.41.8-2.10.82.2-2.2-2.22.32.32.22.22.2-0.5
Context. condit. distance diff. score0.20.20.20.4-0.40.40.4-0.4-0.50.50.40.50.50.5-0.3
Locomotion velocity, session 10.80.92.51.1-0.91.50.7-0.7-0.70.60.60.70.70.7-1.6
Locomotion distance, session 12.32.93.31.8-1.71.81.7-1.7-1.71.61.71.71.71.7-1.7
Locomotion velocity, session 26.27.310.93.0-2.73.32.4-2.4-2.42.52.32.72.72.7-3.2
Locomotion distance, session 21.52.02.81.6-1.51.71.4-1.4-1.41.31.31.31.31.3-1.6
Locomotion velocity, session 30.80.92.61.1-0.91.50.6-0.7-0.70.70.60.80.80.8-1.6
Locomotion distance, session 30.70.81.1-0.70.9-0.2-1.01.01.0-1.0-1.1-1.0-1.0-1.0-0.0
Stereotopy head waving bouts, day 31.41.62.11.3-1.40.91.5-1.4-1.31.41.51.21.21.2-0.7
Stereotopy head waving duration, day 32.12.53.01.7-1.71.51.7-1.7-1.61.61.71.51.51.5-1.3
Locomotion velocity, session 70.40.41.90.8-0.61.20.3-0.3-0.40.40.20.30.30.3-1.4
Locomotion distance, session 70.20.21.10.5-0.40.90.2-0.2-0.30.20.10.20.20.2-1.0
Stereotopy head waving bouts, day 70.10.10.20.3-0.3-0.10.4-0.4-0.30.40.50.30.30.30.2
Stereotopy head waving duration, day 70.10.10.5-0.30.2-0.6-0.10.00.2-0.1-0.0-0.1-0.1-0.10.7
Locomotion velocity, session 80.60.71.20.9-0.81.10.6-0.6-0.70.70.60.90.90.9-1.1
Locomotion distance, session 81.01.51.71.3-1.21.31.2-1.2-1.31.21.21.21.21.2-1.2
Degree of sensitization distance1.92.02.31.5-1.51.51.4-1.4-1.51.41.41.31.31.3-1.4
Degree of sensitization stereotypy0.50.50.7-0.70.8-0.8-0.70.60.8-0.6-0.6-0.7-0.7-0.70.8
Conditioned locomotion1.72.02.7-1.21.4-0.4-1.61.61.5-1.6-1.6-1.6-1.6-1.60.0
Cocaine response after cond. corrected0.20.20.3-0.50.5-0.5-0.30.40.4-0.4-0.3-0.5-0.5-0.50.5
Cocaine response after cond. not corrected0.30.40.5-0.70.6-0.5-0.60.60.6-0.7-0.6-0.6-0.6-0.60.5
Cocaine response before conditioning0.10.10.50.3-0.20.60.0-0.0-0.1-0.1-0.10.10.10.1-0.7
Saline control response0.00.10.40.2-0.00.5-0.00.10.1-0.0-0.10.10.10.1-0.6
Bone: connectivity density1.52.36.3-1.81.6-2.4-1.21.21.1-1.2-1.0-1.2-1.2-1.22.5
Bone: cortical apparent density0.40.60.9-0.60.8-0.2-0.91.00.8-0.8-0.9-0.8-0.8-0.80.1
Bone: cortical area0.81.23.71.3-1.01.80.8-0.8-0.70.90.70.80.80.8-1.9
Bone: cortical porosity0.10.10.20.2-0.2-0.10.4-0.4-0.30.30.40.30.30.30.1
Bone: cortical porosity0.10.10.20.3-0.30.20.5-0.4-0.30.30.40.20.20.2-0.2
Bone: cortical thickness0.91.54.31.4-1.12.00.8-0.8-0.80.90.70.90.90.9-2.1
Bone: cortical thickness0.10.10.2-0.30.3-0.4-0.30.20.1-0.1-0.1-0.2-0.2-0.20.4
Bone: cortical tissue density0.40.60.9-0.70.8-0.3-0.91.00.8-0.9-0.9-0.8-0.8-0.80.2
Condit. Reinf. active minus inactive responses1.61.82.11.4-1.41.21.4-1.4-1.41.41.41.41.41.4-1.1
Condit. Reinf. active-inactive response ratio0.30.30.40.4-0.50.10.6-0.6-0.60.50.70.60.60.60.0
Condit. Reinf. active responses2.93.53.91.9-1.91.71.9-1.9-2.01.91.91.91.91.9-1.5
Condit. Reinf. inactive responses2.22.73.21.7-1.71.41.8-1.7-1.81.71.71.61.61.6-1.2
Incentive salience index mean2.43.03.91.9-1.82.01.6-1.6-1.71.71.61.71.71.7-1.9
Condit. Reinf. lever presses4.15.77.02.6-2.52.72.3-2.3-2.32.32.22.32.32.3-2.5
Condit. Reinf. active minus inactive responses0.10.10.4-0.1-0.1-0.40.2-0.2-0.10.20.20.40.40.40.7
Condit. Reinf. active-inactive response ratio0.70.91.60.6-0.8-0.00.9-1.0-0.90.91.01.31.31.30.3
Condit. Reinf. active responses0.00.00.1-0.0-0.1-0.10.0-0.10.00.10.10.20.20.20.3
Condit. Reinf. inactive responses0.10.10.20.00.10.4-0.20.20.3-0.2-0.3-0.3-0.3-0.3-0.4
Condit. Reinf. lever presses0.50.70.90.7-0.80.20.9-1.0-0.80.91.01.01.01.0-0.1
Condit. Reinf. lever reinforcers received0.00.00.1-0.10.0-0.2-0.00.00.1-0.0-0.00.10.10.10.4
Conditioned reinforcement - actives0.30.51.3-0.10.40.8-0.60.60.7-0.7-0.8-0.8-0.8-0.8-1.1
Conditioned reinforcement - inactives0.40.51.10.9-0.71.00.7-0.7-0.70.80.60.40.40.4-1.0
Conditioned locomotion0.20.20.40.5-0.50.30.6-0.6-0.50.60.60.40.40.4-0.2
Patch foraging indifference point 0 sec0.71.41.71.2-1.20.91.2-1.2-1.11.31.21.31.31.3-0.7
Patch foraging indifference point AUC1.01.44.71.4-1.22.10.8-0.8-0.80.80.70.90.90.9-2.2
Delay disc. indifference point, 0s delay1.71.92.4-1.41.3-1.2-1.51.51.5-1.4-1.5-1.2-1.2-1.21.2
Delay disc. indifference point, 16s delay10.111.113.5-3.33.4-2.1-3.73.63.7-3.7-3.7-3.5-3.5-3.51.4
Delay disc. indifference point, 2s delay3.03.34.6-1.81.8-1.2-2.12.12.1-1.9-2.1-1.8-1.8-1.81.0
Delay disc. indifference point, 24s delay1.01.21.6-1.21.2-0.9-1.21.31.2-1.2-1.2-0.9-0.9-0.90.8
Delay disc. indifference point, 4s delay2.62.84.1-1.31.5-0.1-2.01.82.0-1.8-2.0-1.9-1.9-1.9-0.5
Delay disc. indifference point, 8s delay4.14.86.4-2.02.2-1.2-2.52.42.5-2.3-2.5-2.4-2.4-2.40.7
Indifference point function ln k0.40.71.0-1.00.9-1.0-0.80.80.7-0.8-0.7-0.9-0.9-0.91.0
Indifference point function log k0.40.71.0-1.00.9-1.0-0.80.80.7-0.8-0.7-0.9-0.9-0.91.0
Patch foraging total patch changes 0 sec0.91.72.21.3-1.41.11.3-1.4-1.31.51.31.41.41.4-0.8
Patch foraging total patch changes 12 sec1.41.85.11.6-1.32.21.0-1.0-0.91.10.91.01.01.0-2.2
Patch foraging total patch changes 18 sec1.42.14.11.7-1.52.01.2-1.2-1.21.31.11.31.31.3-2.0
Patch foraging total patch changes 24 sec0.71.12.01.2-1.11.30.9-1.0-1.01.00.90.90.90.9-1.4
Patch foraging total patch changes 6 sec2.53.84.82.1-2.02.21.8-1.9-1.81.91.81.91.91.9-2.1
Patch foraging time to switch 0 sec3.77.610.0-3.02.9-3.2-2.62.72.6-2.6-2.5-2.6-2.6-2.63.0
Patch foraging water rate 0 sec2.65.412.52.7-2.43.41.9-1.9-1.91.91.71.81.81.8-3.5
Patch foraging water rate 12 sec4.08.49.93.2-3.03.02.9-2.9-2.92.92.82.72.72.7-3.0
Patch foraging water rate 18 sec1.21.82.31.5-1.51.51.3-1.3-1.31.41.21.31.31.3-1.5
Patch foraging water rate 24 sec1.92.73.31.8-1.81.71.7-1.7-1.51.71.61.51.51.5-1.7
Patch foraging water rate 6 sec0.40.62.30.9-0.71.30.5-0.5-0.50.50.40.50.50.5-1.5
Seeking ratio, delayed vs. immediate footshock2.12.52.8-1.71.6-1.7-1.51.41.5-1.5-1.5-1.6-1.6-1.61.7
Distance traveled before self-admin0.10.10.30.3-0.30.50.2-0.2-0.30.30.20.10.10.1-0.5
Distance traveled after self-admin2.12.63.01.7-1.71.51.6-1.7-1.61.61.61.71.71.7-1.3
Extensor digitorum longus weight0.10.40.70.7-0.60.80.6-0.5-0.90.60.60.60.60.6-0.8
Bone: elastic displacement0.50.60.8-0.70.8-0.4-0.90.90.9-0.8-0.9-0.6-0.6-0.60.5
Bone: elastic work0.00.00.00.00.10.1-0.10.10.10.1-0.10.20.20.20.1
Bone: endosteal estimation0.40.91.5-1.11.0-1.2-0.80.80.9-0.9-0.8-1.0-1.0-1.01.1
Bone: endosteal perimeter0.00.00.10.2-0.20.10.3-0.3-0.10.30.20.10.10.1-0.2
Epididymis fat weight2.68.911.13.0-3.02.03.2-3.3-3.33.33.33.03.03.0-1.6
Delta time in closed arm before/after self-admin0.30.31.4-0.50.3-1.20.0-0.1-0.1-0.00.10.10.10.11.2
Delta time in open arm before/after self-admin0.10.10.2-0.10.10.3-0.40.20.4-0.2-0.4-0.4-0.4-0.4-0.2
Diff in mean of infusions in LGA sessions0.81.01.81.1-1.11.40.9-0.9-1.00.90.90.80.80.8-1.2
Delay discount exponential model param7.17.910.42.7-2.91.73.2-3.1-3.23.03.22.92.92.9-1.1
Extinction: sum of active levers before priming0.00.00.20.3-0.30.50.1-0.1-0.00.0-0.00.00.00.0-0.3
Active lever presses in extinction session 60.30.30.80.7-0.60.80.3-0.3-0.30.30.30.30.30.3-0.9
Bone: final force0.40.70.91.0-0.80.90.8-0.8-0.70.90.80.70.70.7-1.0
Bone: final moment0.40.71.61.0-0.81.20.7-0.7-0.60.80.60.70.70.7-1.3
Food consumed during 24 hour testing period0.60.81.81.0-0.91.30.7-0.7-0.70.70.60.80.80.8-1.3
Glucose6.910.912.03.4-3.42.93.4-3.4-3.53.33.43.43.43.4-2.5
Heart weight0.20.30.90.7-0.50.90.4-0.5-0.30.40.40.40.40.4-1.0
Delay discount hyperbolic model param6.37.19.42.5-2.71.63.1-2.9-3.12.93.12.82.82.8-1.0
Intermittent access intake day 1-15 change0.00.10.40.3-0.10.40.2-0.10.00.10.00.00.00.0-0.6
Intermittent access intake escalation0.00.00.20.1-0.00.20.1-0.00.10.0-0.0-0.0-0.0-0.0-0.4
Intermittent access intake escalation 20.10.10.4-0.00.20.3-0.20.20.4-0.3-0.4-0.4-0.4-0.4-0.6
Intermitt. access day 1 inactive lever presses0.31.01.60.7-0.9-0.21.3-1.1-1.21.11.21.01.01.00.4
Intermitt. access day 15 inactive lever presses0.30.61.20.7-0.80.31.1-0.8-1.10.81.00.60.60.6-0.5
Intermitt. access escalation Index0.00.00.1-0.20.1-0.2-0.1-0.0-0.0-0.1-0.0-0.1-0.1-0.10.3
Intermittent access day 1 total infusions0.50.81.20.9-0.90.61.1-1.1-1.11.01.10.80.80.8-0.3
Intermittent access day 15 total infusions0.30.51.00.7-0.70.51.0-0.9-0.80.80.90.50.50.5-0.3
Intermittent access terminal intake (last 3 days)0.00.00.10.1-0.10.10.4-0.3-0.20.10.2-0.1-0.1-0.1-0.1
Intermittent access total infusions0.20.20.50.5-0.40.40.7-0.6-0.60.50.60.30.30.3-0.3
Intermittent access day 1 locomotion0.81.11.70.9-1.00.51.2-1.3-1.21.11.31.01.01.0-0.1
Intermittent access day 15 total locomotion0.71.31.81.2-1.20.91.3-1.3-1.11.31.21.11.11.1-0.8
Intermittent access total locomotion0.70.81.30.8-0.80.31.1-1.1-1.01.11.10.90.90.90.0
Intermittent access standard deviation1.43.03.7-1.81.8-1.9-1.51.61.6-1.6-1.5-1.8-1.8-1.81.8
Left kidney weight1.67.68.93.0-2.93.02.8-2.7-2.72.82.62.62.62.6-2.8
Right kidney weight1.77.811.93.1-2.93.42.5-2.6-2.52.72.42.62.62.6-3.3
Cocaine induced anxiety0.10.10.4-0.0-0.1-0.60.4-0.3-0.20.30.40.30.30.30.6
Post-drug Anxiety0.10.10.1-0.0-0.1-0.40.2-0.1-0.10.00.20.30.30.30.3
Baseline Anxiety0.40.40.8-0.50.60.1-0.80.80.6-0.9-0.8-0.7-0.7-0.7-0.2
Tail length1.24.95.72.2-2.21.62.3-2.4-2.42.42.42.42.42.4-1.1
Length with tail0.93.85.21.8-1.80.92.1-2.2-2.22.22.32.12.12.1-0.2
Length without tail0.51.72.31.3-1.20.81.4-1.4-1.51.41.51.41.41.4-0.6
Times rat made contact with spout4.65.26.62.2-2.41.42.4-2.3-2.42.62.52.62.62.6-1.1
Lifetime Intake0.00.00.1-0.10.1-0.10.1-0.00.0-0.10.0-0.3-0.3-0.30.2
Liver weight, left0.50.83.51.0-0.71.70.5-0.4-0.50.40.30.50.50.5-1.9
Liver weight, right2.74.65.82.3-2.12.42.0-2.1-2.12.12.02.12.12.1-2.3
Locomotor activity2.33.54.81.9-1.91.31.8-1.8-1.92.01.92.22.22.2-1.3
Locomotor testing distance2.03.54.71.8-1.81.11.9-1.9-2.02.02.02.22.22.2-1.1
Locomotor testing rearing2.55.06.12.4-2.42.52.1-2.2-2.12.22.12.22.22.2-2.2
Locomotion in novel chamber0.70.91.3-0.91.0-0.6-1.11.01.1-1.0-1.1-1.0-1.0-1.00.3
Locomotion in novel chamber post-restriction0.50.81.0-0.50.70.6-0.90.90.8-1.0-1.0-1.0-1.0-1.0-1.0
Fecal boli incidents, locomotor time 10.30.40.9-0.10.40.5-0.70.60.7-0.7-0.8-0.7-0.7-0.7-0.9
Change in fecal boli incidents, locomotor task0.10.10.1-0.20.20.3-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.2
Time >=10cm from walls, locomotor time 10.30.30.50.7-0.70.70.5-0.7-0.60.60.50.40.40.4-0.7
Bouts of movement, locomotor time 10.40.52.5-0.60.3-1.4-0.0-0.00.0-0.00.1-0.4-0.4-0.41.6
Total resting periods, locomotor time 10.30.31.2-0.0-0.3-1.00.5-0.6-0.50.50.60.20.20.21.1
Rest time, locomotor task time 10.81.01.4-0.90.9-1.2-0.90.80.9-0.8-0.8-1.1-1.1-1.11.1
Distance moved, locomotor task time 10.10.10.20.2-0.20.30.2-0.3-0.20.20.20.40.40.4-0.1
Vertical activity count, locomotor time 10.20.50.8-0.70.8-0.0-0.90.90.9-0.9-0.9-0.6-0.6-0.60.0
Time >=10cm from walls, locomotor time 20.40.61.00.9-0.90.90.8-0.9-0.80.80.70.40.40.4-1.0
Bouts of movement, locomotor time 20.20.30.50.5-0.50.20.5-0.7-0.60.70.60.50.50.5-0.2
Total resting periods, locomotor time 20.00.10.10.0-0.1-0.30.2-0.4-0.20.30.30.20.20.20.3
Rest time, locomotor task time 20.70.92.6-1.00.9-1.4-0.70.70.8-0.7-0.7-0.9-0.9-0.91.6
Distance moved, locomotor task time 21.01.21.51.1-1.20.91.2-1.2-1.21.21.21.11.11.1-0.7
Vertical activity count, locomotor time 20.10.10.2-0.20.20.3-0.40.40.4-0.4-0.5-0.3-0.3-0.3-0.4
Light reinforcement 11.53.85.52.1-2.02.31.8-1.9-1.81.91.81.91.91.9-1.9
Light reinforcement 22.03.03.81.6-1.71.11.9-1.9-1.91.82.01.91.91.9-0.6
Bone: marrow area0.41.01.4-1.11.0-1.2-0.80.80.9-0.9-0.9-1.0-1.0-1.01.1
Bone: maximum diameter0.40.72.11.0-0.81.30.6-0.6-0.50.70.50.50.50.5-1.5
Bone: maximum force0.00.00.00.1-0.0-0.10.2-0.2-0.10.20.10.10.10.10.0
Bone: maximum moment0.00.00.10.1-0.00.10.1-0.10.00.10.00.10.10.1-0.3
Mean time between licks in bursts1.43.45.6-2.11.9-2.4-1.61.61.6-1.6-1.5-1.8-1.8-1.82.3
Mean num. licks in bursts0.40.60.8-0.60.7-0.2-0.90.90.9-0.8-0.9-0.8-0.8-0.80.1
Cd content in liver1.61.82.0-1.41.3-1.4-1.31.21.3-1.4-1.2-1.4-1.4-1.41.2
Co content in liver0.10.10.5-0.40.3-0.6-0.20.30.2-0.3-0.2-0.3-0.3-0.30.7
Cu content in liver0.10.20.3-0.20.30.2-0.50.50.5-0.5-0.5-0.4-0.4-0.4-0.4
Fe content in liver0.10.10.30.4-0.20.50.3-0.3-0.30.10.3-0.0-0.0-0.0-0.5
K content in liver0.40.42.0-0.70.5-1.2-0.20.30.2-0.2-0.1-0.1-0.1-0.11.4
Mg content in liver0.20.20.3-0.40.5-0.4-0.50.50.5-0.4-0.5-0.5-0.5-0.50.3
Mn content in liver0.30.30.50.3-0.6-0.20.6-0.6-0.50.70.70.70.70.70.5
Na content in liver0.80.81.61.1-0.91.30.7-0.7-0.70.80.60.80.80.8-1.2
Rb content in liver3.84.45.6-2.02.3-1.2-2.22.22.2-2.4-2.3-2.4-2.4-2.41.0
Se content in liver1.01.11.41.1-1.21.21.1-1.1-1.21.01.11.01.01.0-1.0
Sr content in liver1.10.91.11.1-1.01.10.9-0.9-0.90.90.90.90.90.9-1.0
Zn content in liver1.41.52.0-1.11.3-0.5-1.41.41.4-1.4-1.4-1.4-1.4-1.40.2
Bone: minimum diameter0.30.50.90.8-0.70.80.8-0.8-0.60.70.70.50.50.5-0.9
Time in familiar zone, hab. session 10.90.82.51.1-0.91.40.8-0.8-0.80.70.70.50.50.5-1.6
Time in novel zone, hab. session 11.01.02.6-1.21.0-1.5-0.90.90.9-0.9-0.9-0.6-0.6-0.61.6
Total zone transitions, hab. session 14.25.86.52.6-2.52.32.5-2.5-2.52.52.52.32.32.3-2.1
Total locomotion distance, hab. session 14.76.77.92.8-2.72.82.6-2.5-2.52.52.52.52.52.5-2.7
Locomotion velocity, hab. session 14.36.07.52.7-2.52.72.4-2.4-2.42.32.32.32.32.3-2.6
Time in familiar zone, hab. session 22.22.42.7-1.61.7-1.6-1.51.51.5-1.5-1.4-1.6-1.6-1.61.5
Time in novel zone, hab. session 20.40.50.60.7-0.80.70.6-0.6-0.60.60.50.70.70.7-0.7
Total zone transitions, hab. session 22.43.04.31.6-1.70.82.0-2.0-1.91.92.11.91.91.9-0.4
Total locomotion distance, hab. session 23.03.94.81.9-2.01.42.1-2.1-2.12.12.22.12.12.1-1.1
Locomotion velocity, hab. session 22.33.03.81.7-1.81.11.9-1.9-1.91.92.01.91.91.9-0.9
Novel to familiar place preference ratio0.10.10.10.3-0.30.30.2-0.2-0.30.40.20.30.30.3-0.3
Novelty place preference0.00.00.10.1-0.10.2-0.10.10.00.1-0.10.10.10.1-0.3
Time in novel zone, NPP test0.00.00.00.1-0.10.2-0.10.10.00.1-0.10.00.00.0-0.2
Total zone transitions, NPP test6.49.29.93.1-3.12.73.1-3.1-3.03.13.13.13.13.1-2.4
Total locomotion distance, NPP test5.77.88.62.9-2.92.42.9-2.8-2.92.92.92.92.92.9-2.1
Locomotion velocity, NPP test6.18.69.43.0-3.02.53.0-3.0-3.03.13.13.13.13.1-2.2
Intraocular pressure0.60.81.3-1.00.8-1.2-0.70.80.7-0.8-0.8-1.0-1.0-1.01.2
Delta distance traveled before/after self-admin2.62.73.91.5-1.70.91.6-1.8-1.61.81.72.02.02.0-0.7
Delta ambulatory time before/after self-admin2.93.64.81.8-2.01.21.8-2.0-1.82.01.92.22.22.2-1.0
Parametrial fat weight4.19.611.63.0-3.22.23.3-3.3-3.43.23.43.23.23.2-2.0
Pavlov. Cond. lever latency3.13.97.3-2.32.0-2.7-1.71.71.7-1.7-1.6-1.7-1.7-1.72.7
Pavlov. Cond. magazine entry latency0.81.14.11.2-1.01.80.7-0.7-0.70.60.50.60.60.6-2.0
Pavlov. Cond. change in total contacts2.32.53.91.8-1.62.01.5-1.5-1.51.41.31.41.41.4-2.0
Pavlov. Cond. index score3.24.08.52.3-2.02.81.7-1.7-1.71.71.51.71.71.7-2.9
Pavlov. Cond. latency score2.43.07.82.0-1.72.61.4-1.3-1.31.41.21.41.41.4-2.8
Pavlov. Cond. lever contacts3.44.16.92.3-2.02.61.8-1.8-1.81.81.71.81.81.8-2.6
Pavlov. Cond. magazine entry number2.73.46.8-2.11.9-2.5-1.61.61.7-1.6-1.4-1.5-1.5-1.52.6
Pavlov. Cond. intertrial magazine entries1.01.21.4-1.21.1-1.1-1.11.11.1-1.0-1.0-1.0-1.0-1.01.1
Pavlov. Cond. lever-magazine prob. diff.2.93.67.92.2-1.92.71.6-1.6-1.61.61.41.61.61.6-2.8
Pavlov. Cond. response bias4.25.18.12.6-2.32.92.1-2.1-2.12.11.92.02.02.0-2.9
Pavlov. Cond. lever latency2.53.44.3-1.81.8-1.2-2.02.01.9-2.0-2.1-2.0-2.0-2.01.0
Pavlov. Cond. magazine entry latency2.42.93.51.7-1.71.31.8-1.9-1.81.81.91.71.71.7-1.2
Pavlov. Cond. change in total contacts2.13.44.31.8-1.91.22.0-2.0-1.92.02.12.02.02.0-1.0
Pavlov. Cond. index score4.25.76.62.4-2.41.82.5-2.6-2.42.52.62.52.52.5-1.6
Pavlov. Cond. latency score4.66.17.22.5-2.51.92.6-2.7-2.62.62.72.62.62.6-1.6
Pavlov. Cond. lever contacts2.73.74.81.9-1.91.32.1-2.2-2.02.12.22.02.02.0-1.1
Pavlov. Cond. magazine entry number0.80.91.1-1.00.9-0.9-1.01.01.0-1.0-1.0-0.9-0.9-0.90.8
Pavlov. Cond. intertrial magazine entries0.00.00.0-0.1-0.00.1-0.10.10.1-0.0-0.10.00.00.0-0.0
Pavlov. Cond. lever-magazine prob. diff.4.45.96.82.5-2.41.92.6-2.6-2.52.52.62.52.52.5-1.6
Pavlov. Cond. response bias1.01.41.91.2-1.10.71.3-1.3-1.21.31.41.31.31.3-0.6
Time in closed arm before self-admin0.10.20.8-0.40.3-0.80.00.2-0.0-0.2-0.0-0.3-0.3-0.30.9
Time in closed arm after self-admin0.50.52.7-0.40.1-1.50.4-0.3-0.50.20.50.20.20.21.6
Time in open arm before self-admin2.62.84.51.9-1.72.11.4-1.6-1.51.61.41.61.61.6-2.0
Time in open arm after self-admin0.80.82.71.1-0.91.60.4-0.7-0.40.70.50.60.60.6-1.6
Bone: periosteal estimation0.10.10.50.4-0.30.60.3-0.3-0.20.30.20.20.20.2-0.7
Bone: periosteal perimeter0.91.62.41.5-1.21.51.3-1.3-1.11.31.21.11.11.1-1.5
Bone: post-yield work0.10.10.4-0.1-0.0-0.60.3-0.3-0.20.30.30.20.20.20.6
Progressive ratio test 1 active lever presses0.81.01.40.9-1.00.41.2-1.2-1.11.11.21.11.11.10.0
Progressive ratio test 1 breakpoint0.80.91.30.8-0.90.41.1-1.1-1.11.01.11.11.11.1-0.0
Progressive ratio test 1 inactive lever presses0.81.21.51.1-1.11.11.2-1.1-1.21.11.11.01.01.0-0.9
Progressive ratio test 2 active lever presses2.73.24.01.9-1.81.82.0-1.9-1.91.81.81.71.71.7-1.5
Progressive ratio test 2 breakpoint3.13.64.32.0-1.91.92.1-2.0-1.91.91.91.81.81.8-1.6
Progressive ratio test 2 inactive lever presses0.71.11.81.1-1.11.01.3-1.1-1.31.11.20.80.80.8-0.9
Incentive Sensitization - Responses1.52.12.51.5-1.51.61.6-1.4-1.41.51.41.31.31.3-1.5
Incentive Sensitization - Breakpoint1.62.12.51.6-1.51.61.6-1.5-1.41.51.41.31.31.3-1.5
Sum of active levers in priming session hrs 5-60.40.42.40.4-0.31.3-0.20.30.2-0.3-0.4-0.1-0.1-0.1-1.6
Progressive ratio0.50.71.1-0.70.9-0.5-1.01.01.0-1.0-1.0-0.8-0.8-0.80.2
Food seeking constrained by brief footshock0.10.10.20.2-0.2-0.10.2-0.4-0.30.30.40.40.40.40.2
Seeking ratio, punishment vs. effort0.30.40.60.6-0.70.40.8-0.8-0.80.70.80.70.70.7-0.1
Retroperitoneal fat weight2.912.515.13.9-3.73.83.5-3.6-3.63.43.43.33.33.3-3.6
Reaction time number correct0.10.20.70.00.10.7-0.40.40.3-0.5-0.5-0.5-0.5-0.5-0.8
Reaction time mean minus median0.10.10.3-0.30.4-0.1-0.50.40.5-0.5-0.5-0.2-0.2-0.20.1
Reaction time mean minus median AUC0.20.61.0-0.80.8-0.9-0.80.70.8-0.7-0.7-0.5-0.5-0.51.0
Reaction time num false alarms0.70.91.1-1.01.0-0.8-0.90.91.0-1.0-1.0-1.0-1.0-1.00.9
Reaction time num false alarms AUC0.40.70.8-0.80.8-0.5-0.80.80.9-0.9-0.9-0.9-0.9-0.90.6
Reaction time trials correct on left0.10.20.70.00.10.7-0.40.40.3-0.5-0.5-0.5-0.5-0.5-0.8
Reaction time trials on left0.10.20.70.10.10.7-0.30.30.3-0.5-0.4-0.4-0.4-0.4-0.8
Reaction time mean0.30.52.8-0.80.6-1.5-0.30.30.2-0.2-0.2-0.2-0.2-0.21.7
Reaction time mean AUC0.40.63.4-0.80.6-1.6-0.20.20.2-0.2-0.1-0.1-0.1-0.11.8
Median of all reaction times0.40.63.3-0.70.5-1.6-0.10.20.0-0.1-0.0-0.1-0.1-0.11.8
Reaction time omissions0.30.40.50.6-0.60.40.6-0.6-0.60.60.60.70.70.7-0.4
Reaction time false alarm rate0.70.91.6-1.01.0-1.2-0.90.90.9-0.9-0.8-0.8-0.8-0.81.3
Reaction time premature initiation rate1.01.41.61.3-1.31.11.2-1.2-1.21.31.21.21.21.2-1.0
Reaction time premature initiations0.81.52.71.4-1.31.61.1-1.1-1.11.11.01.01.01.0-1.6
Std. dev. reaction times0.20.31.2-0.70.6-1.0-0.40.40.4-0.4-0.3-0.2-0.2-0.21.1
Reaction time trials completed0.10.20.70.10.10.7-0.30.30.3-0.5-0.4-0.4-0.4-0.4-0.8
Reaction time trials AUC0.10.21.00.2-0.10.9-0.20.20.1-0.3-0.3-0.3-0.3-0.3-1.0
Run reversals in cocaine runway, females1.21.22.41.2-1.01.31.0-1.0-1.00.90.90.90.90.9-1.6
Run reversals in cocaine runway, males0.10.10.20.3-0.30.30.3-0.3-0.40.30.30.10.10.1-0.2
Latency to leave start box in cocaine runway1.61.82.31.4-1.41.51.5-1.5-1.31.31.41.21.21.2-1.2
Latency to leave start box in cocaine runway, F0.20.30.60.5-0.50.40.7-0.8-0.50.50.70.50.50.5-0.1
Latency to leave start box in cocaine runway, M4.84.55.22.3-2.22.32.1-2.1-2.12.12.02.02.02.0-2.1
Std. dev. time between licks in bursts1.31.82.6-1.31.3-1.2-1.21.21.2-1.2-1.2-1.6-1.6-1.61.0
Total sessions with >9 infusions0.00.00.1-0.10.10.1-0.10.00.2-0.2-0.2-0.3-0.3-0.30.0
Short access day 1 total inactive lever presses0.20.30.40.5-0.50.50.6-0.5-0.60.60.50.50.50.5-0.6
Short access day 10 total inactive lever presses0.10.10.40.3-0.40.20.5-0.3-0.60.40.40.30.30.3-0.2
Short access day 1 total infusions0.20.20.4-0.40.4-0.2-0.40.40.5-0.5-0.5-0.6-0.6-0.60.3
Short access day 10 total infusions0.00.10.3-0.20.2-0.30.10.0-0.1-0.20.0-0.2-0.2-0.20.5
Short access total infusions0.70.91.2-1.01.0-0.8-0.80.80.9-1.0-0.9-1.1-1.1-1.10.9
Short access day 1 locomotion0.10.10.2-0.30.3-0.3-0.20.20.4-0.3-0.2-0.3-0.3-0.30.5
Short access day 10 total locomotion0.61.13.1-1.21.1-1.5-0.90.80.8-0.9-0.7-0.8-0.8-0.81.8
Short access total locomotion0.50.60.8-0.80.8-0.7-0.80.60.8-0.9-0.8-0.9-0.9-0.90.8
One hour access (0.3 mA shock)0.20.20.70.10.10.7-0.30.30.5-0.2-0.4-0.4-0.4-0.4-0.9
Compulsive drug intake0.10.10.3-0.20.30.1-0.50.60.4-0.3-0.5-0.4-0.4-0.4-0.2
One hour access (shock baseline)0.30.50.70.8-0.70.80.8-0.8-0.60.70.70.50.50.5-0.7
Social response proportion1.01.21.4-1.11.2-1.1-1.00.91.2-1.1-0.9-1.2-1.2-1.20.7
Social responses1.92.53.1-1.51.7-1.2-1.61.61.7-1.6-1.6-1.8-1.8-1.80.8
Social time0.91.31.7-0.50.90.6-1.21.21.3-1.2-1.3-1.3-1.3-1.3-1.1
Soleus weight0.51.52.21.4-1.21.51.1-1.1-1.21.21.11.11.11.1-1.4
Bone: stiffness0.00.00.0-0.10.1-0.20.1-0.10.10.10.0-0.2-0.2-0.20.1
Tibialis anterior weight0.20.71.20.8-0.90.60.9-0.9-1.10.80.90.90.90.9-0.6
Time to tail flick, vehicle, before self-admin0.30.30.7-0.40.6-0.0-0.30.60.2-0.8-0.5-0.8-0.8-0.8-0.0
Time to tail flick, vehicle, after self-admin2.73.64.8-2.22.1-2.1-1.91.91.8-1.8-1.8-1.6-1.6-1.62.1
Time to tail flick, test, before self-admin2.82.94.1-1.41.6-0.3-2.01.82.0-1.9-2.0-1.9-1.9-1.9-0.2
Time to tail flick, test, after self-admin1.41.52.2-1.21.2-0.9-1.51.31.5-1.3-1.4-1.0-1.0-1.00.7
Delta time to tail flick, vehicle, before/after SA1.01.01.4-1.11.1-1.1-1.21.11.2-0.9-1.1-0.7-0.7-0.71.0
Delta time to tail flick, test, before/after SA0.50.51.30.2-0.3-0.70.6-0.6-0.60.70.70.80.80.81.1
Tibia length3.28.910.93.2-3.13.32.8-2.8-2.82.92.63.03.03.0-3.2
Ambulatory time before self-admin0.10.10.2-0.00.20.4-0.30.30.2-0.2-0.3-0.4-0.4-0.4-0.5
Ambulatory time after self-admin2.32.73.21.8-1.81.61.5-1.7-1.51.71.61.71.71.7-1.5
Bone: tissue strength0.10.10.2-0.10.20.1-0.30.30.4-0.2-0.4-0.1-0.1-0.1-0.2
Total heroin consumption0.30.30.70.6-0.50.50.6-0.8-0.60.70.70.40.40.4-0.4
Bone: trabecular number0.81.22.1-1.21.3-1.4-1.01.00.9-1.0-0.9-1.0-1.0-1.01.4
Bone: trabecular spacing0.60.82.21.0-0.91.40.7-0.6-0.70.80.60.70.70.7-1.5
Bone: trabecular thickness1.41.83.3-1.41.4-1.7-1.11.11.2-1.1-1.1-1.2-1.2-1.21.8
Bone: trabecular tissue density0.20.21.30.2-0.10.9-0.30.40.2-0.3-0.4-0.3-0.3-0.3-1.1
Water consumed over 24 hours3.04.05.12.2-2.12.31.8-1.9-1.82.01.82.02.02.0-2.2
Number of responses in last shaping day0.00.00.20.2-0.20.40.2-0.1-0.10.10.10.10.10.1-0.4