Hub : Genes

Cul7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Cul7 0.15 0.09 8.0e-15 0.17 0.13 0.17 0.17 2.1e-15 2.2e-12 1.4e-15 3.0e-15
2 PL mRNA stability Cul7 0.02 0.02 3.5e-03 0.01 0.02 0.01 0.01 9.0e-03 3.9e-03 1.3e-02 8.2e-03
3 NAcc gene expression Cul7 0.33 0.26 3.2e-13 0.12 0.11 0.12 0.12 2.8e-14 1.1e-12 2.8e-13 3.1e-13
4 OFC gene expression Cul7 0.22 0.13 7.0e-04 0.15 0.13 0.12 0.13 2.5e-04 6.6e-04 9.9e-04 5.4e-04
5 PL gene expression Cul7 0.16 0.1 0.0e+00 0.18 0.18 0.17 0.18 5.7e-19 4.3e-19 7.5e-19 4.2e-19
6 LHb gene expression Cul7 0.39 0.15 2.8e-08 0.3 0.23 0.23 0.3 6.7e-08 3.0e-06 3.5e-06 9.4e-08
7 Brain gene expression Cul7 0.46 0.18 0.0e+00 0.41 0.41 0.41 0.41 2.3e-40 3.1e-40 1.1e-40 7.1e-41
8 IL gene expression Cul7 0.27 0.13 1.2e-05 0.21 0.18 0.17 0.2 8.8e-06 4.8e-05 6.9e-05 1.6e-05
9 Liver gene expression Cul7 0.07 0.05 7.7e-05 0.03 0.03 0.03 0.03 2.9e-04 6.3e-04 3.8e-04 3.1e-04
10 BLA gene expression Cul7 0.11 0.07 4.0e-04 0.06 0.06 0.01 0.05 2.6e-04 6.8e-04 1.1e-01 7.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.50.82.2-0.80.90.60.6-0.70.5-0.60.7-1.41.5
Area under the delay curve7.47.910.9-3.12.83.23.1-3.03.1-3.32.9-1.21.3
BMI with tail4.313.916.04.0-3.9-3.8-3.83.8-3.73.7-3.63.5-3.5
BMI without tail12.525.928.95.4-5.4-5.2-5.25.3-5.15.1-5.04.5-4.6
Body weight3.012.613.93.7-3.7-3.6-3.73.7-3.63.6-3.63.1-3.1
Weight adjusted by age0.20.20.40.4-0.5-0.3-0.50.5-0.50.3-0.60.5-0.7
Bone surface1.52.64.0-1.61.81.41.5-1.51.4-1.31.6-1.82.0
Bone volume0.61.01.8-1.01.10.90.9-0.90.8-0.81.0-1.31.3
Breakpoint value in progressive ratio session0.00.00.2-0.0-0.00.10.2-0.20.2-0.20.10.4-0.4
Number of licking bursts3.03.65.02.0-1.9-2.1-2.12.1-2.12.2-2.10.4-0.4
Context. condit. distance diff. score0.10.10.20.4-0.3-0.4-0.40.4-0.50.4-0.40.4-0.1
Locomotion velocity, session 11.01.03.10.8-1.0-0.7-0.60.7-0.70.6-0.81.7-1.7
Locomotion distance, session 12.33.03.31.8-1.8-1.8-1.71.7-1.71.7-1.81.7-1.6
Locomotion velocity, session 26.37.410.92.6-2.8-2.5-2.52.5-2.52.3-2.73.2-3.3
Locomotion distance, session 21.62.22.91.6-1.5-1.5-1.41.4-1.41.4-1.51.7-1.6
Locomotion velocity, session 30.80.93.10.8-0.9-0.6-0.60.7-0.60.4-0.71.6-1.8
Locomotion distance, session 30.60.71.1-0.90.80.90.9-0.90.9-1.11.00.1-0.1
Stereotopy head waving bouts, day 31.31.51.91.4-1.3-1.3-1.31.4-1.31.3-1.20.7-0.9
Stereotopy head waving duration, day 32.22.63.01.7-1.7-1.6-1.61.7-1.61.6-1.61.4-1.5
Locomotion velocity, session 70.50.51.90.5-0.6-0.4-0.40.4-0.40.3-0.31.4-1.3
Locomotion distance, session 70.20.31.20.4-0.4-0.3-0.20.3-0.30.1-0.21.1-0.9
Stereotopy head waving bouts, day 70.20.20.30.5-0.4-0.5-0.60.5-0.50.5-0.50.2-0.3
Stereotopy head waving duration, day 70.10.10.5-0.20.30.20.1-0.20.2-0.10.1-0.70.6
Locomotion velocity, session 80.60.71.40.8-0.9-0.7-0.80.8-0.70.6-1.01.2-1.0
Locomotion distance, session 81.11.62.01.4-1.3-1.3-1.31.2-1.41.2-1.31.3-1.0
Degree of sensitization distance2.02.02.41.5-1.5-1.4-1.41.4-1.41.4-1.41.4-1.2
Degree of sensitization stereotypy0.50.50.6-0.70.80.70.6-0.70.7-0.70.7-0.80.8
Conditioned locomotion1.41.62.5-1.41.21.51.4-1.31.5-1.61.50.1-0.0
Cocaine response after cond. corrected0.20.30.4-0.50.50.50.5-0.50.5-0.50.5-0.60.6
Cocaine response after cond. not corrected0.40.40.6-0.70.70.70.8-0.70.7-0.70.6-0.60.5
Cocaine response before conditioning0.10.10.50.2-0.3-0.2-0.00.1-0.00.1-0.10.6-0.7
Saline control response0.00.10.3-0.0-0.00.00.1-0.10.1-0.1-0.10.6-0.5
Bone: connectivity density1.21.95.2-1.21.40.91.0-1.00.8-0.81.0-2.32.3
Bone: cortical apparent density0.70.91.3-1.11.01.11.0-1.01.1-1.10.9-0.20.3
Bone: cortical area1.01.54.31.0-1.1-0.9-0.90.9-0.90.7-0.82.1-2.0
Bone: cortical porosity0.10.10.20.4-0.3-0.4-0.40.3-0.40.5-0.3-0.1-0.0
Bone: cortical porosity0.10.10.10.4-0.3-0.3-0.30.3-0.40.3-0.20.3-0.4
Bone: cortical thickness1.32.15.61.2-1.4-1.1-1.01.2-1.10.9-1.12.3-2.4
Bone: cortical thickness0.00.00.1-0.10.20.00.10.00.0-0.00.0-0.20.2
Bone: cortical tissue density0.60.81.1-1.10.91.10.9-0.91.0-1.00.9-0.20.3
Condit. Reinf. active minus inactive responses1.61.82.01.4-1.4-1.4-1.31.4-1.41.4-1.41.0-1.1
Condit. Reinf. active-inactive response ratio0.20.20.40.5-0.5-0.5-0.50.5-0.60.6-0.6-0.1-0.1
Condit. Reinf. active responses2.73.33.71.9-1.9-1.9-1.91.9-1.91.9-1.91.5-1.6
Condit. Reinf. inactive responses2.22.63.01.7-1.7-1.7-1.71.7-1.71.7-1.61.3-1.3
Incentive salience index mean2.42.93.71.7-1.8-1.6-1.61.7-1.61.5-1.61.8-1.9
Condit. Reinf. lever presses4.25.66.62.3-2.5-2.3-2.32.4-2.32.2-2.22.5-2.6
Condit. Reinf. active minus inactive responses0.10.10.6-0.00.1-0.0-0.1-0.0-0.00.1-0.2-0.80.7
Condit. Reinf. active-inactive response ratio0.60.61.20.8-0.7-0.9-0.80.8-0.81.0-1.1-0.40.4
Condit. Reinf. active responses0.00.00.2-0.10.10.10.0-0.10.1-0.00.0-0.50.3
Condit. Reinf. inactive responses0.10.10.3-0.20.10.30.2-0.10.2-0.30.40.4-0.5
Condit. Reinf. lever presses0.40.50.80.7-0.7-0.8-0.80.8-0.80.9-0.80.1-0.1
Condit. Reinf. lever reinforcers received0.00.00.2-0.20.10.20.1-0.10.1-0.10.1-0.50.3
Conditioned reinforcement - actives0.70.71.2-0.80.70.90.9-0.90.9-1.01.10.3-0.4
Conditioned reinforcement - inactives1.01.12.21.1-1.1-1.0-1.00.9-1.00.9-0.71.4-1.5
Conditioned locomotion0.00.00.00.2-0.1-0.2-0.2-0.1-0.20.10.10.0-0.1
Patch foraging indifference point 0 sec0.81.21.61.1-1.2-1.1-1.31.2-1.31.2-1.20.7-0.8
Patch foraging indifference point AUC1.31.54.21.0-1.3-0.7-0.81.0-0.80.6-0.92.1-2.1
Delay disc. indifference point, 0s delay1.41.52.1-1.31.11.41.3-1.21.3-1.41.0-1.11.0
Delay disc. indifference point, 16s delay10.510.713.5-3.63.43.63.6-3.53.6-3.73.5-1.51.6
Delay disc. indifference point, 2s delay2.93.24.9-2.01.72.22.0-1.82.0-2.21.7-0.90.8
Delay disc. indifference point, 24s delay1.41.31.8-1.31.21.21.3-1.21.3-1.30.9-0.80.8
Delay disc. indifference point, 4s delay2.52.64.5-1.71.32.01.8-1.71.7-2.11.80.6-0.5
Delay disc. indifference point, 8s delay4.54.66.6-2.42.12.52.4-2.32.3-2.62.3-0.70.8
Indifference point function ln k0.40.50.6-0.70.80.70.7-0.70.8-0.70.8-0.80.8
Indifference point function log k0.40.50.6-0.70.80.70.7-0.70.8-0.70.8-0.80.8
Patch foraging total patch changes 0 sec1.01.72.11.3-1.4-1.3-1.41.4-1.41.4-1.30.9-0.9
Patch foraging total patch changes 12 sec1.51.94.91.1-1.4-0.9-1.11.2-1.20.9-1.02.1-2.2
Patch foraging total patch changes 18 sec1.82.34.11.4-1.6-1.2-1.31.5-1.31.1-1.32.0-2.0
Patch foraging total patch changes 24 sec1.01.32.11.1-1.2-0.9-1.01.2-1.10.9-0.91.4-1.4
Patch foraging total patch changes 6 sec2.33.43.71.8-1.9-1.7-1.91.8-1.91.7-1.81.9-1.9
Patch foraging time to switch 0 sec5.28.09.7-2.93.02.72.7-2.72.7-2.52.7-3.13.1
Patch foraging water rate 0 sec3.86.013.82.3-2.5-1.9-2.02.1-1.91.7-1.83.6-3.7
Patch foraging water rate 12 sec5.88.99.93.1-3.1-2.9-2.93.0-2.92.8-2.83.1-3.0
Patch foraging water rate 18 sec1.41.92.41.4-1.5-1.2-1.31.4-1.31.2-1.21.5-1.5
Patch foraging water rate 24 sec2.13.03.51.9-1.9-1.7-1.81.7-1.71.6-1.61.8-1.6
Patch foraging water rate 6 sec0.60.82.90.7-0.8-0.5-0.50.5-0.50.3-0.41.7-1.6
Seeking ratio, delayed vs. immediate footshock2.12.42.9-1.51.71.41.5-1.71.5-1.51.7-1.71.6
Distance traveled before self-admin0.20.20.40.4-0.5-0.3-0.50.4-0.50.3-0.20.7-0.6
Distance traveled after self-admin3.74.15.12.2-2.2-2.2-2.22.1-2.32.1-2.21.4-1.4
Extensor digitorum longus weight0.10.40.70.7-0.6-0.6-0.60.6-0.60.5-0.50.8-0.8
Bone: elastic displacement0.30.40.5-0.70.60.70.7-0.60.7-0.70.5-0.30.3
Bone: elastic work0.00.00.00.0-0.0-0.0-0.10.1-0.10.0-0.20.0-0.1
Bone: endosteal estimation0.40.91.4-0.91.00.90.8-0.90.9-0.91.0-1.11.2
Bone: endosteal perimeter0.00.00.00.1-0.0-0.0-0.20.0-0.10.00.00.1-0.0
Epididymis fat weight1.74.15.32.1-2.0-2.2-2.22.2-2.22.3-2.21.0-1.0
Delta time in closed arm before/after self-admin0.20.20.30.4-0.2-0.5-0.50.3-0.50.5-0.4-0.40.4
Delta time in open arm before/after self-admin0.30.30.6-0.60.50.70.6-0.50.6-0.60.7-0.40.4
Diff in mean of infusions in LGA sessions0.60.61.60.8-0.8-0.6-0.60.6-0.50.5-0.61.2-1.3
Delay discount exponential model param7.37.710.83.1-2.8-3.3-3.12.9-3.03.3-2.91.0-1.1
Extinction: sum of active levers before priming0.00.00.00.1-0.1-0.1-0.0-0.00.00.0-0.0-0.20.0
Active lever presses in extinction session 60.20.20.90.2-0.4-0.1-0.10.10.0-0.0-0.20.9-1.0
Bone: final force0.40.71.10.9-0.8-0.8-0.90.9-0.80.7-0.71.1-0.9
Bone: final moment0.50.81.90.9-0.8-0.7-0.80.8-0.70.6-0.71.4-1.2
Food consumed during 24 hour testing period0.70.81.90.8-1.0-0.7-0.70.8-0.70.6-0.81.3-1.4
Glucose4.87.28.92.9-2.8-2.9-2.82.8-2.82.9-3.01.8-1.9
Heart weight1.11.62.2-1.31.31.41.5-1.41.5-1.41.4-0.30.5
Delay discount hyperbolic model param6.46.89.83.0-2.6-3.1-2.92.8-2.93.1-2.70.9-1.0
Intermittent access intake day 1-15 change0.30.31.30.2-0.3-0.2-0.10.2-0.10.1-0.11.1-1.0
Intermittent access intake escalation0.10.10.30.0-0.0-0.10.1-0.00.1-0.10.10.6-0.5
Intermittent access intake escalation 20.30.31.50.3-0.4-0.2-0.20.2-0.20.1-0.11.2-1.0
Intermitt. access day 1 inactive lever presses1.41.52.11.4-1.3-1.4-1.31.3-1.31.4-1.10.9-0.8
Intermitt. access day 15 inactive lever presses2.02.22.91.7-1.5-1.7-1.51.4-1.51.6-1.31.5-1.1
Intermitt. access escalation Index0.00.00.2-0.10.10.00.0-0.10.00.00.1-0.40.4
Intermittent access day 1 total infusions0.60.71.11.0-0.7-1.1-1.10.8-1.11.1-0.8-0.30.1
Intermittent access day 15 total infusions0.40.40.80.8-0.5-0.9-0.80.5-0.80.8-0.5-0.0-0.1
Intermittent access terminal intake (last 3 days)0.20.30.60.6-0.3-0.8-0.70.3-0.70.7-0.3-0.30.2
Intermittent access total infusions0.20.30.40.5-0.2-0.7-0.60.2-0.60.6-0.3-0.60.5
Intermittent access day 1 locomotion0.40.50.80.6-0.3-0.7-0.80.4-0.80.7-0.6-0.90.7
Intermittent access day 15 total locomotion0.30.40.60.7-0.6-0.8-0.70.5-0.70.7-0.50.3-0.3
Intermittent access total locomotion0.30.31.30.20.1-0.4-0.30.1-0.30.4-0.2-1.11.1
Intermittent access standard deviation3.43.64.3-1.92.11.71.8-1.91.8-1.72.0-2.02.0
Left kidney weight0.51.35.40.7-0.9-0.6-0.60.7-0.50.4-0.52.3-2.1
Right kidney weight0.20.73.50.2-0.4-0.0-0.00.20.0-0.2-0.01.9-1.8
Cocaine induced anxiety0.10.10.20.3-0.3-0.5-0.30.3-0.30.4-0.4-0.00.3
Post-drug Anxiety0.10.10.4-0.10.2-0.10.1-0.00.10.1-0.1-0.40.6
Baseline Anxiety0.20.20.3-0.50.50.50.6-0.50.6-0.50.5-0.30.2
Tail length1.85.46.42.4-2.4-2.4-2.42.5-2.42.4-2.42.0-2.0
Length with tail0.10.30.50.4-0.4-0.5-0.50.5-0.50.4-0.50.7-0.7
Length without tail2.65.76.9-2.62.62.52.5-2.62.5-2.52.4-1.81.8
Times rat made contact with spout4.45.16.52.3-2.4-2.4-2.52.5-2.52.4-2.61.1-1.1
Lifetime Intake0.10.10.6-0.00.3-0.1-0.0-0.3-0.00.00.3-0.80.6
Liver weight, left0.61.03.10.8-0.9-0.7-0.70.7-0.60.6-1.01.7-1.6
Liver weight, right0.60.91.11.0-0.9-0.9-0.91.0-0.90.9-1.01.0-1.0
Locomotor activity1.93.14.41.7-1.8-1.8-1.91.9-1.91.9-2.11.3-1.1
Locomotor testing distance1.62.73.71.6-1.6-1.7-1.81.7-1.81.8-1.91.1-1.0
Locomotor testing rearing3.35.25.92.3-2.4-2.2-2.32.3-2.32.1-2.32.1-2.3
Locomotion in novel chamber0.70.81.1-1.00.91.11.0-1.00.9-1.01.0-0.20.4
Locomotion in novel chamber post-restriction1.11.31.8-1.00.91.21.3-1.31.3-1.31.30.6-0.7
Fecal boli incidents, locomotor time 10.40.40.6-0.40.40.80.7-0.60.7-0.70.80.8-0.7
Change in fecal boli incidents, locomotor task0.10.10.4-0.30.10.40.2-0.20.2-0.30.20.3-0.6
Time >=10cm from walls, locomotor time 10.40.40.60.7-0.7-0.6-0.60.6-0.70.5-0.40.7-0.8
Bouts of movement, locomotor time 10.50.62.7-0.10.40.00.0-0.1-0.00.10.3-1.61.6
Total resting periods, locomotor time 10.40.41.40.5-0.2-0.6-0.50.4-0.60.6-0.2-1.21.2
Rest time, locomotor task time 10.60.71.0-0.70.80.80.8-0.80.8-0.81.0-0.80.8
Distance moved, locomotor task time 10.00.00.1-0.1-0.10.0-0.20.1-0.20.1-0.30.1-0.1
Vertical activity count, locomotor time 10.60.71.1-1.00.81.00.9-0.90.9-1.00.6-0.20.1
Time >=10cm from walls, locomotor time 20.80.81.40.8-1.0-0.7-0.80.8-0.90.7-0.51.2-1.2
Bouts of movement, locomotor time 20.30.30.60.6-0.6-0.6-0.80.6-0.80.7-0.50.2-0.3
Total resting periods, locomotor time 20.10.10.20.2-0.2-0.2-0.40.2-0.40.4-0.2-0.30.2
Rest time, locomotor task time 20.81.02.2-0.81.00.90.8-0.70.8-0.81.0-1.51.4
Distance moved, locomotor task time 21.01.21.51.0-1.2-1.1-1.21.1-1.21.2-1.10.7-0.7
Vertical activity count, locomotor time 20.20.20.3-0.40.20.40.4-0.40.4-0.50.20.5-0.5
Light reinforcement 12.24.04.52.1-2.1-2.0-2.01.9-2.01.9-2.02.0-2.1
Light reinforcement 22.43.24.31.9-1.7-2.1-2.01.9-2.02.1-2.00.8-0.7
Bone: marrow area0.51.01.3-0.91.11.00.9-1.00.9-1.01.1-1.01.1
Bone: maximum diameter0.40.72.30.6-0.7-0.5-0.60.6-0.50.4-0.51.5-1.4
Bone: maximum force0.00.00.10.2-0.0-0.2-0.20.2-0.20.2-0.10.00.2
Bone: maximum moment0.00.00.10.1-0.0-0.1-0.10.1-0.10.1-0.10.3-0.1
Mean time between licks in bursts1.92.65.7-1.51.61.31.3-1.41.3-1.21.4-2.32.4
Mean num. licks in bursts0.40.40.7-0.70.60.80.7-0.70.7-0.80.70.00.0
Cd content in liver0.80.91.2-1.00.91.01.1-1.11.0-1.11.1-0.50.5
Co content in liver0.00.00.00.2-0.2-0.2-0.20.2-0.20.2-0.2-0.10.1
Cu content in liver0.50.61.0-0.80.60.90.8-0.80.9-1.00.80.4-0.4
Fe content in liver0.40.40.7-0.70.80.70.8-0.80.6-0.70.9-0.30.2
K content in liver1.01.03.3-0.91.00.60.6-0.70.6-0.50.6-1.81.8
Mg content in liver1.92.02.4-1.51.51.51.5-1.51.5-1.51.5-1.00.9
Mn content in liver0.70.81.21.0-1.0-1.0-1.11.0-1.01.1-1.0-0.20.2
Na content in liver0.10.10.60.2-0.2-0.1-0.20.2-0.10.1-0.20.7-0.8
Rb content in liver6.07.59.0-2.92.92.93.0-3.02.9-3.03.0-1.61.5
Se content in liver0.20.20.30.4-0.5-0.4-0.40.4-0.40.3-0.30.5-0.5
Sr content in liver0.80.70.90.9-1.0-0.9-0.90.9-0.90.8-0.90.8-0.8
Zn content in liver3.84.25.9-2.12.02.32.4-2.32.3-2.42.4-0.50.5
Bone: minimum diameter0.30.61.10.8-0.7-0.7-0.80.7-0.80.7-0.51.1-0.9
Time in familiar zone, hab. session 11.11.02.90.9-0.9-0.7-0.70.7-0.80.6-0.51.7-1.7
Time in novel zone, hab. session 11.11.12.3-1.01.00.90.9-0.90.9-0.90.7-1.51.5
Total zone transitions, hab. session 14.25.97.02.6-2.5-2.6-2.52.5-2.52.5-2.42.1-2.1
Total locomotion distance, hab. session 14.76.77.42.7-2.7-2.6-2.52.6-2.52.4-2.52.7-2.7
Locomotion velocity, hab. session 14.36.17.22.5-2.6-2.4-2.42.4-2.32.3-2.42.7-2.6
Time in familiar zone, hab. session 22.22.32.7-1.51.71.41.4-1.51.5-1.31.6-1.51.7
Time in novel zone, hab. session 20.40.40.70.7-0.8-0.6-0.60.6-0.60.5-0.70.7-0.9
Total zone transitions, hab. session 22.33.04.31.9-1.7-2.0-2.01.9-2.02.1-2.00.5-0.4
Total locomotion distance, hab. session 22.93.84.92.1-2.0-2.1-2.12.1-2.12.2-2.11.0-1.0
Locomotion velocity, hab. session 22.22.93.91.8-1.8-1.9-1.91.8-1.92.0-1.90.8-0.8
Novel to familiar place preference ratio0.10.10.20.3-0.3-0.2-0.40.4-0.30.3-0.30.3-0.3
Novelty place preference0.00.00.10.0-0.10.0-0.10.10.00.0-0.10.2-0.3
Time in novel zone, NPP test0.00.00.10.0-0.10.0-0.10.10.0-0.0-0.10.2-0.2
Total zone transitions, NPP test6.79.610.93.3-3.2-3.3-3.23.2-3.23.2-3.32.6-2.4
Total locomotion distance, NPP test5.77.99.03.0-2.9-2.9-3.02.9-2.93.0-3.02.1-2.1
Locomotion velocity, NPP test6.18.69.93.1-3.0-3.1-3.13.1-3.03.1-3.22.2-2.2
Intraocular pressure0.91.21.6-1.11.01.11.1-1.11.1-1.01.2-1.31.3
Delta distance traveled before/after self-admin4.34.66.92.2-2.3-2.4-2.32.3-2.42.4-2.60.9-0.9
Delta ambulatory time before/after self-admin3.63.95.72.0-2.1-2.1-2.12.3-2.22.1-2.40.8-0.7
Parametrial fat weight5.911.513.53.5-3.5-3.6-3.53.7-3.63.6-3.62.6-2.5
Pavlov. Cond. lever latency3.03.86.7-1.82.01.71.7-1.81.7-1.61.6-2.62.6
Pavlov. Cond. magazine entry latency1.21.54.51.0-1.2-0.9-0.80.9-0.80.7-0.72.0-2.1
Pavlov. Cond. change in total contacts2.42.63.91.6-1.7-1.5-1.41.5-1.51.4-1.31.9-2.0
Pavlov. Cond. index score3.34.28.61.9-2.1-1.7-1.71.8-1.71.6-1.62.9-2.9
Pavlov. Cond. latency score2.53.27.91.6-1.7-1.4-1.41.5-1.41.2-1.32.7-2.8
Pavlov. Cond. lever contacts4.14.87.52.2-2.2-2.0-2.02.1-2.01.9-1.92.7-2.7
Pavlov. Cond. magazine entry number2.42.96.1-1.61.71.51.4-1.51.4-1.31.3-2.32.5
Pavlov. Cond. intertrial magazine entries0.91.11.2-1.01.11.01.0-1.01.0-1.01.0-1.11.1
Pavlov. Cond. lever-magazine prob. diff.3.13.97.91.8-2.0-1.7-1.61.7-1.71.5-1.52.7-2.8
Pavlov. Cond. response bias4.85.98.82.4-2.5-2.3-2.22.3-2.22.1-2.12.9-3.0
Pavlov. Cond. lever latency2.12.83.8-1.81.71.91.8-1.81.8-1.91.8-0.80.8
Pavlov. Cond. magazine entry latency1.61.82.41.5-1.3-1.6-1.41.4-1.41.5-1.41.0-0.9
Pavlov. Cond. change in total contacts2.02.73.61.7-1.6-1.8-1.81.8-1.81.9-1.80.9-1.0
Pavlov. Cond. index score4.05.26.42.4-2.3-2.5-2.42.4-2.42.5-2.31.6-1.6
Pavlov. Cond. latency score4.45.46.82.5-2.3-2.6-2.52.4-2.52.6-2.41.6-1.6
Pavlov. Cond. lever contacts2.33.24.21.9-1.8-2.0-1.91.9-1.92.0-1.81.1-1.1
Pavlov. Cond. magazine entry number0.70.81.1-1.00.81.00.9-0.90.9-1.00.8-0.80.8
Pavlov. Cond. intertrial magazine entries0.00.00.0-0.1-0.10.1-0.00.0-0.0-0.1-0.1-0.0-0.0
Pavlov. Cond. lever-magazine prob. diff.3.95.06.32.4-2.2-2.5-2.42.3-2.42.5-2.31.5-1.5
Pavlov. Cond. response bias0.70.91.41.1-0.9-1.1-1.11.1-1.11.2-1.00.5-0.5
Time in closed arm before self-admin0.40.41.3-0.50.60.40.4-0.40.4-0.30.4-1.01.2
Time in closed arm after self-admin0.50.52.5-0.10.3-0.1-0.00.0-0.20.30.1-1.41.6
Time in open arm before self-admin3.43.65.81.9-1.9-1.8-1.81.7-1.71.6-1.82.3-2.4
Time in open arm after self-admin0.80.82.00.8-1.0-0.6-0.80.7-0.70.5-0.71.3-1.4
Bone: periosteal estimation0.10.20.80.3-0.3-0.2-0.30.2-0.20.1-0.10.9-0.8
Bone: periosteal perimeter0.71.22.21.1-1.0-1.0-1.11.0-1.00.9-0.91.5-1.4
Bone: post-yield work0.10.10.50.10.1-0.2-0.10.0-0.10.2-0.1-0.50.7
Progressive ratio test 1 active lever presses1.11.11.81.2-0.9-1.3-1.21.1-1.21.3-1.1-0.40.2
Progressive ratio test 1 breakpoint0.90.91.41.1-0.9-1.2-1.11.0-1.11.2-1.0-0.1-0.1
Progressive ratio test 1 inactive lever presses1.11.21.61.3-1.1-1.3-1.21.0-1.21.2-0.90.8-1.0
Progressive ratio test 2 active lever presses1.41.52.01.4-1.2-1.4-1.31.1-1.31.2-1.10.9-1.2
Progressive ratio test 2 breakpoint2.02.32.91.7-1.5-1.7-1.61.4-1.61.5-1.41.2-1.4
Progressive ratio test 2 inactive lever presses0.60.71.21.0-0.8-1.1-0.90.7-0.90.9-0.60.7-0.8
Incentive Sensitization - Responses1.51.52.01.3-1.3-1.3-1.21.0-1.21.1-1.01.4-1.4
Incentive Sensitization - Breakpoint1.51.62.11.3-1.3-1.3-1.21.1-1.21.2-1.01.4-1.5
Sum of active levers in priming session hrs 5-60.80.81.3-0.80.60.91.0-0.91.1-1.10.90.7-0.8
Progressive ratio0.60.71.1-1.00.91.00.9-0.80.9-1.00.8-0.10.3
Food seeking constrained by brief footshock0.00.00.10.1-0.1-0.1-0.10.2-0.10.1-0.3-0.10.1
Seeking ratio, punishment vs. effort0.50.60.90.9-0.9-0.9-0.80.8-0.80.9-0.90.4-0.5
Retroperitoneal fat weight1.96.29.12.5-2.6-2.3-2.32.3-2.32.1-2.23.0-3.0
Reaction time number correct0.20.30.9-0.10.00.40.4-0.20.4-0.50.50.8-1.0
Reaction time mean minus median0.10.20.3-0.50.40.50.5-0.40.5-0.50.2-0.1-0.0
Reaction time mean minus median AUC0.50.60.9-0.90.80.80.8-0.80.8-0.70.5-1.00.8
Reaction time num false alarms0.70.91.2-1.01.00.91.0-1.00.9-1.01.1-0.90.8
Reaction time num false alarms AUC0.50.70.9-0.80.80.80.9-0.90.8-0.90.9-0.60.4
Reaction time trials correct on left0.20.30.9-0.10.00.40.4-0.20.4-0.50.50.8-1.0
Reaction time trials on left0.20.20.9-0.1-0.00.30.4-0.20.3-0.40.40.8-1.0
Reaction time mean0.50.72.8-0.50.70.20.4-0.40.3-0.10.2-1.71.6
Reaction time mean AUC0.60.73.3-0.50.70.10.3-0.40.3-0.00.1-1.81.8
Median of all reaction times0.40.62.8-0.30.6-0.00.2-0.30.10.10.0-1.71.7
Reaction time omissions0.40.50.80.8-0.7-0.8-0.80.7-0.80.8-0.90.3-0.2
Reaction time false alarm rate0.71.01.7-1.01.10.90.9-1.00.8-0.90.9-1.31.2
Reaction time premature initiation rate1.01.31.61.3-1.2-1.2-1.21.2-1.31.2-1.10.8-0.8
Reaction time premature initiations1.11.52.31.3-1.3-1.1-1.11.2-1.11.1-0.91.5-1.5
Std. dev. reaction times0.30.41.2-0.60.70.40.5-0.50.4-0.30.3-1.11.0
Reaction time trials completed0.20.20.9-0.1-0.00.30.4-0.20.3-0.40.40.8-1.0
Reaction time trials AUC0.20.21.20.1-0.20.20.2-0.00.2-0.30.31.0-1.1
Run reversals in cocaine runway, females0.90.92.40.8-0.9-0.6-0.70.8-0.70.6-0.91.5-1.3
Run reversals in cocaine runway, males0.10.10.10.4-0.3-0.3-0.30.2-0.30.3-0.10.2-0.3
Latency to leave start box in cocaine runway2.32.53.01.7-1.6-1.6-1.51.4-1.61.6-1.41.5-1.7
Latency to leave start box in cocaine runway, F0.20.20.40.6-0.4-0.6-0.50.4-0.60.6-0.40.1-0.2
Latency to leave start box in cocaine runway, M5.55.36.92.3-2.4-2.2-2.22.2-2.22.2-2.22.5-2.6
Std. dev. time between licks in bursts1.61.93.0-1.41.41.41.4-1.41.4-1.41.7-1.21.1
Total sessions with >9 infusions0.00.00.00.10.0-0.1-0.1-0.2-0.10.00.2-0.0-0.2
Short access day 1 total inactive lever presses0.30.31.10.4-0.4-0.4-0.30.2-0.30.2-0.11.1-1.0
Short access day 10 total inactive lever presses1.11.32.41.2-1.2-1.1-1.01.0-1.01.0-0.81.5-1.4
Short access day 1 total infusions0.20.30.5-0.50.50.50.5-0.70.5-0.60.7-0.30.1
Short access day 10 total infusions0.20.21.30.20.2-0.4-0.2-0.1-0.20.30.0-1.10.9
Short access total infusions0.40.51.2-0.50.70.40.5-0.70.5-0.40.7-1.10.9
Short access day 1 locomotion0.60.60.8-0.70.80.70.7-0.90.7-0.80.9-0.90.8
Short access day 10 total locomotion2.62.95.7-1.61.81.51.4-1.61.4-1.41.4-2.42.2
Short access total locomotion2.12.22.6-1.51.61.51.4-1.61.4-1.51.6-1.51.3
One hour access (0.3 mA shock)0.30.30.5-0.40.30.50.5-0.50.5-0.70.70.5-0.6
Compulsive drug intake0.10.10.5-0.2-0.00.30.3-0.10.3-0.40.20.7-0.7
One hour access (shock baseline)0.20.20.40.6-0.4-0.7-0.60.4-0.60.6-0.40.0-0.1
Social response proportion0.91.01.3-1.01.10.91.0-1.11.0-0.91.1-0.60.9
Social responses2.02.53.5-1.71.81.71.7-1.71.7-1.71.9-0.90.8
Social time1.21.62.4-1.11.01.31.5-1.31.4-1.51.41.0-1.0
Soleus weight0.41.31.61.1-1.1-1.1-1.11.1-1.01.1-1.11.3-1.3
Bone: stiffness0.00.00.1-0.00.2-0.00.0-0.1-0.00.00.1-0.10.3
Tibialis anterior weight0.20.60.80.8-0.8-0.9-0.80.8-0.80.9-0.80.4-0.3
Time to tail flick, vehicle, before self-admin0.20.20.7-0.30.50.30.6-0.80.5-0.40.60.1-0.2
Time to tail flick, vehicle, after self-admin2.83.03.7-1.91.91.71.7-1.71.7-1.61.4-1.81.9
Time to tail flick, test, before self-admin4.34.25.9-2.22.02.32.4-2.42.3-2.42.2-0.20.3
Time to tail flick, test, after self-admin0.60.61.1-0.90.80.90.9-0.71.0-1.00.6-0.10.1
Delta time to tail flick, vehicle, before/after SA0.80.71.1-1.10.91.00.8-0.61.0-0.90.6-0.91.0
Delta time to tail flick, test, before/after SA1.00.91.40.8-0.7-0.9-1.11.2-1.01.1-1.2-0.60.5
Tibia length2.57.08.32.6-2.8-2.4-2.62.6-2.42.4-2.72.9-2.9
Ambulatory time before self-admin0.10.10.4-0.1-0.00.20.1-0.10.1-0.30.30.6-0.6
Ambulatory time after self-admin3.53.84.72.0-2.1-2.0-2.12.1-2.22.0-2.11.4-1.3
Bone: tissue strength0.10.10.2-0.40.30.40.3-0.30.4-0.40.10.2-0.1
Total heroin consumption0.10.10.10.4-0.2-0.4-0.40.2-0.40.4-0.2-0.10.2
Bone: trabecular number0.50.81.3-0.91.00.70.8-0.80.7-0.70.9-1.11.1
Bone: trabecular spacing0.71.02.20.8-1.0-0.7-0.80.8-0.70.6-0.91.5-1.5
Bone: trabecular thickness1.01.22.4-1.01.10.90.9-1.00.8-0.81.0-1.51.5
Bone: trabecular tissue density0.20.31.1-0.1-0.10.30.2-0.20.3-0.40.31.0-1.0
Water consumed over 24 hours2.53.05.01.7-1.8-1.5-1.61.7-1.61.4-1.62.2-2.2
Number of responses in last shaping day0.20.20.60.4-0.4-0.3-0.40.3-0.40.3-0.30.8-0.8