Hub : Genes

Ctcfl2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Ctcfl2 0.23 0.1 0.0e+00 0.36 0.35 0.35 0.36 4.1e-30 4.0e-29 5.3e-29 9.5e-30
2 PL gene expression Ctcfl2 0.36 0.11 0.0e+00 0.39 0.41 0.4 0.41 2.7e-45 1.6e-47 1.2e-46 2.3e-48
3 IC gene expression Ctcfl2 0.37 0.12 0.0e+00 0.4 0.4 0.38 0.4 6.5e-18 8.5e-18 6.9e-17 4.6e-18
4 pVTA mRNA stability Ctcfl2 0.11 0.09 3.2e-06 0.06 0.06 0.05 0.06 3.2e-05 1.7e-05 9.0e-05 2.6e-05
5 NAcc gene expression Ctcfl2 0.56 0 0.0e+00 0.38 0.39 0.4 0.4 1.2e-61 6.8e-64 8.4e-65 4.3e-65
6 NAcc mRNA stability Ctcfl2 0.04 0.03 2.5e-08 0.05 0.04 0.04 0.04 9.2e-08 2.3e-07 1.0e-06 2.1e-07
7 Brain mRNA stability Ctcfl2 0.37 0.12 0.0e+00 0.45 0.47 0.47 0.46 8.4e-46 2.9e-48 1.3e-48 1.4e-47
8 BLA gene expression Ctcfl2 0.3 0.12 0.0e+00 0.33 0.36 0.36 0.38 4.1e-18 3.8e-20 3.1e-20 1.6e-21
9 LHb mRNA stability Ctcfl2 0.15 0.1 2.4e-03 0.09 0.09 0.1 0.08 3.6e-03 3.2e-03 2.1e-03 5.3e-03
10 Brain gene expression Ctcfl2 0.62 0.1 0.0e+00 0.49 0.51 0.51 0.5 1.2e-51 5.1e-54 3.8e-55 2.7e-53
11 LHb gene expression Ctcfl2 0.31 0.14 2.6e-07 0.26 0.2 0.21 0.21 9.3e-07 1.5e-05 9.9e-06 1.0e-05
12 Adipose gene expression Ctcfl2 0.04 0.03 7.2e-07 0.04 0.05 0.05 0.04 1.1e-05 2.5e-06 5.0e-06 9.7e-06
13 IL gene expression Ctcfl2 0.31 0.14 7.1e-07 0.2 0.23 0.21 0.21 1.9e-05 3.6e-06 8.4e-06 9.2e-06
14 Adipose mRNA stability Ctcfl2 0.12 0.08 4.7e-12 0.09 0.1 0.1 0.1 7.2e-10 1.5e-11 4.4e-11 4.0e-11
15 OFC gene expression Ctcfl2 0.52 0.2 7.7e-11 0.34 0.36 0.33 0.35 8.1e-09 2.1e-09 1.2e-08 3.7e-09
16 Liver gene expression Ctcfl2 0.03 0.03 2.0e-03 0.01 0.01 0.01 0.01 2.2e-02 1.1e-02 1.0e-02 2.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Bone: apparent density0.10.10.2-0.2-0.2-0.4-0.4-0.4-0.3-0.2-0.3-0.2-0.2-0.2-0.3-0.3-0.3-0.1-0.4
Area under the delay curve0.00.00.30.20.10.1-0.20.10.20.20.2-0.10.3-0.1-0.0-0.1-0.0-0.1-0.5
BMI with tail0.10.41.0-0.4-0.5-0.4-0.6-0.5-0.6-0.5-0.4-0.9-0.4-0.9-0.5-0.6-1.0-0.90.8
BMI without tail0.00.10.60.10.20.20.00.10.1-0.4-0.1-0.3-0.1-0.3-0.1-0.2-0.4-0.50.8
Body weight0.31.52.6-1.2-1.1-1.2-1.0-1.1-1.0-1.6-1.2-1.2-1.5-1.2-1.2-1.2-1.5-1.40.1
Weight adjusted by age0.00.00.1-0.4-0.1-0.10.1-0.1-0.20.2-0.20.00.1-0.10.00.10.20.1-0.1
Bone surface1.12.02.9-1.4-1.4-1.7-1.5-1.6-1.4-1.4-1.6-1.1-1.4-1.1-1.5-1.5-1.5-1.2-1.2
Bone volume0.81.42.2-1.3-1.1-1.5-1.3-1.4-1.2-1.2-1.4-0.9-1.3-0.9-1.3-1.2-1.0-0.8-0.9
Breakpoint value in progressive ratio session1.82.13.11.81.31.41.61.30.91.71.31.61.51.51.61.61.61.60.7
Number of licking bursts0.71.12.4-0.8-1.0-1.0-1.0-1.0-1.0-0.9-0.9-0.8-0.9-0.9-1.0-1.1-1.6-1.4-1.0
Context. condit. distance diff. score0.10.20.60.10.20.10.40.20.40.60.30.80.40.70.30.40.40.40.0
Locomotion velocity, session 10.10.10.4-0.3-0.2-0.1-0.5-0.1-0.2-0.20.0-0.5-0.1-0.3-0.3-0.4-0.6-0.60.2
Locomotion distance, session 10.10.10.20.30.40.40.50.40.40.20.40.40.20.50.30.30.1-0.10.3
Locomotion velocity, session 20.80.91.71.01.11.01.31.11.10.70.81.30.71.21.00.90.60.31.0
Locomotion distance, session 20.20.20.40.50.50.40.70.60.60.00.20.60.10.60.40.3-0.1-0.50.7
Locomotion velocity, session 30.20.20.50.60.50.50.30.50.40.70.70.30.70.30.40.40.10.3-0.1
Locomotion distance, session 30.10.10.30.20.20.20.40.20.20.40.40.50.30.40.30.40.40.5-0.3
Stereotopy head waving bouts, day 30.10.20.3-0.2-0.4-0.4-0.4-0.4-0.4-0.5-0.4-0.5-0.4-0.5-0.4-0.4-0.3-0.5-0.5
Stereotopy head waving duration, day 30.60.81.2-0.8-0.8-0.9-0.8-0.8-0.8-1.0-1.0-0.8-0.9-0.8-0.8-0.9-0.9-1.1-0.7
Locomotion velocity, session 70.10.10.50.10.1-0.00.10.10.20.30.20.40.30.50.20.30.60.70.1
Locomotion distance, session 70.10.20.60.30.20.20.30.10.20.40.10.60.30.50.30.40.70.8-0.3
Stereotopy head waving bouts, day 70.30.30.6-0.5-0.6-0.6-0.7-0.6-0.6-0.3-0.4-0.5-0.3-0.6-0.5-0.5-0.6-0.4-0.8
Stereotopy head waving duration, day 70.81.01.5-0.9-1.0-1.0-1.2-0.9-1.0-0.7-0.8-1.1-0.7-1.1-1.0-1.0-1.2-0.9-1.0
Locomotion velocity, session 80.00.00.3-0.10.10.1-0.10.10.10.30.30.10.30.10.0-0.1-0.5-0.30.2
Locomotion distance, session 80.40.61.30.70.80.60.90.80.90.90.81.10.81.10.80.70.40.40.7
Degree of sensitization distance0.00.00.10.1-0.1-0.2-0.2-0.2-0.1-0.1-0.3-0.1-0.1-0.1-0.1-0.00.30.2-0.0
Degree of sensitization stereotypy0.40.40.7-0.6-0.7-0.7-0.8-0.7-0.7-0.5-0.5-0.8-0.5-0.8-0.7-0.7-0.7-0.5-0.6
Conditioned locomotion1.82.02.9-1.5-1.6-1.7-1.2-1.6-1.4-1.5-1.6-0.9-1.6-1.0-1.5-1.4-1.5-1.6-0.9
Cocaine response after cond. corrected0.60.72.3-0.7-0.7-0.6-1.3-0.7-0.8-0.7-0.6-1.5-0.6-1.4-0.8-0.8-0.5-0.50.2
Cocaine response after cond. not corrected0.20.21.3-0.1-0.2-0.1-0.8-0.2-0.4-0.2-0.1-1.1-0.1-1.0-0.3-0.4-0.2-0.10.5
Cocaine response before conditioning1.01.21.91.41.31.31.11.21.11.21.31.11.31.01.21.10.60.70.3
Saline control response4.76.311.1-2.4-2.3-2.4-2.2-2.4-2.3-2.9-2.7-2.3-2.8-2.3-2.5-2.6-2.9-3.3-0.7
Bone: connectivity density0.00.00.20.40.20.10.10.10.10.30.20.30.30.30.20.2-0.00.2-0.4
Bone: cortical apparent density0.70.92.11.00.41.00.60.80.41.41.20.71.30.61.01.01.01.5-0.3
Bone: cortical area0.20.30.7-0.8-0.6-0.8-0.6-0.6-0.5-0.7-0.8-0.4-0.7-0.4-0.6-0.5-0.00.0-0.2
Bone: cortical porosity0.50.51.10.41.00.50.80.61.00.30.31.00.31.10.60.70.70.50.9
Bone: cortical porosity0.40.40.90.40.90.40.70.60.90.30.30.90.31.00.50.60.70.50.8
Bone: cortical thickness0.10.10.3-0.6-0.5-0.5-0.4-0.4-0.4-0.4-0.5-0.3-0.4-0.3-0.4-0.30.00.1-0.2
Bone: cortical thickness0.20.31.0-0.40.5-0.10.60.10.5-0.2-0.30.8-0.20.60.20.41.00.80.3
Bone: cortical tissue density0.71.02.21.10.51.00.60.80.41.51.30.71.30.71.01.01.01.5-0.3
Condit. Reinf. active minus inactive responses4.34.86.62.22.22.22.02.22.22.22.12.12.22.22.22.32.62.51.3
Condit. Reinf. active-inactive response ratio3.74.05.61.92.02.11.72.02.02.22.11.92.21.92.02.12.22.41.3
Condit. Reinf. active responses3.24.05.52.02.02.01.92.02.01.91.92.11.92.12.02.12.32.21.1
Condit. Reinf. inactive responses0.30.30.70.40.50.40.70.50.50.50.50.70.40.60.60.60.80.80.0
Incentive salience index mean2.32.83.71.61.71.71.61.71.71.61.61.81.61.91.71.71.91.81.2
Condit. Reinf. lever presses0.20.20.50.30.50.50.40.50.60.30.40.70.40.70.40.40.50.30.7
Condit. Reinf. active minus inactive responses0.60.81.0-1.0-1.0-1.0-1.0-1.0-1.0-0.9-1.0-1.0-1.0-1.0-1.0-0.9-0.8-0.7-0.2
Condit. Reinf. active-inactive response ratio0.50.60.9-0.8-0.9-0.8-0.9-0.9-0.9-0.7-0.7-0.9-0.7-0.9-0.8-0.8-0.6-0.4-0.6
Condit. Reinf. active responses0.30.50.9-0.8-0.7-0.6-0.5-0.7-0.6-0.9-0.9-0.6-0.9-0.6-0.7-0.7-0.6-0.60.3
Condit. Reinf. inactive responses0.20.31.00.40.50.60.80.50.60.10.10.70.10.70.50.50.50.21.0
Condit. Reinf. lever presses2.53.45.41.71.91.82.31.92.01.81.72.31.72.31.91.91.51.51.2
Condit. Reinf. lever reinforcers received0.10.10.3-0.3-0.2-0.20.0-0.2-0.1-0.4-0.50.0-0.40.0-0.2-0.1-0.1-0.20.6
Conditioned reinforcement - actives0.71.32.41.11.41.21.11.31.40.71.30.70.90.91.11.01.10.91.6
Conditioned reinforcement - inactives0.20.21.0-0.4-0.5-0.4-1.0-0.5-0.40.10.1-0.70.0-0.7-0.4-0.4-0.50.20.2
Conditioned locomotion0.70.91.9-1.1-0.9-1.0-1.4-1.0-0.8-0.8-1.0-1.2-0.8-1.1-1.0-1.0-1.0-0.6-0.1
Patch foraging indifference point 0 sec2.75.16.0-2.4-2.3-2.3-2.1-2.3-2.2-2.5-2.3-2.1-2.5-2.2-2.3-2.3-2.3-2.4-1.2
Patch foraging indifference point AUC1.62.33.6-1.4-1.4-1.6-1.2-1.6-1.3-1.9-1.8-1.1-1.9-1.2-1.6-1.6-1.8-1.7-0.8
Delay disc. indifference point, 0s delay0.50.51.11.00.90.90.60.90.80.71.00.40.90.40.70.60.40.30.3
Delay disc. indifference point, 16s delay0.10.10.4-0.2-0.0-0.1-0.20.00.3-0.6-0.2-0.3-0.4-0.1-0.3-0.3-0.1-0.4-0.4
Delay disc. indifference point, 2s delay0.30.30.9-0.4-0.5-0.6-0.9-0.5-0.40.1-0.2-0.50.1-0.5-0.6-0.6-0.8-0.4-0.8
Delay disc. indifference point, 24s delay0.00.00.3-0.1-0.0-0.00.10.10.2-0.00.10.30.10.3-0.0-0.0-0.0-0.0-0.6
Delay disc. indifference point, 4s delay0.30.31.50.70.20.50.20.3-0.11.20.90.31.10.10.40.40.40.7-0.3
Delay disc. indifference point, 8s delay0.00.00.40.20.00.1-0.20.10.20.20.1-0.10.3-0.2-0.00.00.20.2-0.6
Indifference point function ln k0.20.41.00.60.50.60.20.60.50.90.80.10.90.20.60.60.91.00.5
Indifference point function log k0.20.41.00.60.50.60.20.60.50.90.80.10.90.20.60.60.91.00.5
Patch foraging total patch changes 0 sec2.65.06.3-2.3-2.3-2.3-2.1-2.3-2.2-2.5-2.3-2.0-2.5-2.1-2.3-2.3-2.2-2.3-1.2
Patch foraging total patch changes 12 sec2.83.64.9-1.8-1.9-1.9-1.6-1.9-1.8-2.2-2.0-1.4-2.2-1.5-1.9-2.0-2.2-2.1-1.5
Patch foraging total patch changes 18 sec2.03.15.7-1.9-1.7-2.0-1.5-1.9-1.5-2.4-2.1-1.3-2.4-1.4-1.8-1.7-1.4-1.4-1.0
Patch foraging total patch changes 24 sec0.30.41.6-0.7-0.6-0.6-0.4-0.7-0.6-0.4-0.50.0-0.6-0.2-0.6-0.6-1.1-0.7-1.3
Patch foraging total patch changes 6 sec2.13.25.1-1.6-1.8-1.7-1.7-1.9-1.8-1.7-1.7-1.5-1.8-1.7-1.8-1.9-2.3-2.1-1.1
Patch foraging time to switch 0 sec0.71.53.01.11.21.51.21.31.11.41.71.31.41.31.21.10.81.00.2
Patch foraging water rate 0 sec1.42.94.7-1.5-1.6-1.8-1.5-1.6-1.5-2.1-2.2-1.7-2.1-1.7-1.7-1.7-1.5-1.7-0.8
Patch foraging water rate 12 sec0.10.20.4-0.3-0.5-0.5-0.5-0.5-0.6-0.4-0.6-0.6-0.5-0.7-0.4-0.4-0.3-0.1-0.6
Patch foraging water rate 18 sec0.10.21.1-0.2-0.4-0.3-0.3-0.4-0.40.60.0-0.10.3-0.2-0.1-0.0-0.00.6-1.1
Patch foraging water rate 24 sec0.00.10.30.20.1-0.20.10.00.1-0.2-0.5-0.0-0.2-0.1-0.00.10.50.3-0.4
Patch foraging water rate 6 sec0.60.81.5-0.9-1.1-1.2-0.9-1.1-1.0-0.7-1.2-0.8-0.9-0.9-0.9-0.7-0.20.1-0.9
Seeking ratio, delayed vs. immediate footshock2.53.14.1-2.0-1.8-1.8-2.0-1.8-1.8-1.6-1.9-1.6-1.6-1.6-1.9-1.9-1.7-1.7-1.2
Distance traveled before self-admin0.91.13.1-1.0-1.3-1.3-1.2-1.4-1.60.6-1.60.2-0.1-0.3-0.8-0.5-0.30.8-1.8
Distance traveled after self-admin0.20.21.2-0.2-0.5-0.4-0.4-0.5-0.70.3-0.50.1-0.0-0.1-0.3-0.3-0.30.0-1.1
Extensor digitorum longus weight1.03.85.51.62.01.92.31.92.21.51.82.31.52.41.92.02.12.31.0
Bone: elastic displacement1.71.93.2-1.3-1.5-1.4-1.6-1.5-1.5-1.4-1.4-1.8-1.3-1.8-1.4-1.3-0.9-0.9-0.8
Bone: elastic work0.60.71.2-0.9-1.0-0.9-0.9-1.0-1.1-0.7-0.8-1.1-0.8-1.1-0.8-0.7-0.2-0.1-0.6
Bone: endosteal estimation0.00.10.1-0.2-0.4-0.3-0.1-0.3-0.3-0.2-0.3-0.1-0.3-0.0-0.2-0.20.10.1-0.2
Bone: endosteal perimeter0.10.20.4-0.5-0.3-0.6-0.3-0.4-0.2-0.6-0.6-0.1-0.60.0-0.4-0.3-0.0-0.1-0.0
Epididymis fat weight1.75.88.2-2.9-2.5-2.7-2.4-2.6-2.1-2.8-2.8-2.2-2.7-2.3-2.5-2.3-1.9-1.6-1.6
Delta time in closed arm before/after self-admin0.20.20.6-0.4-0.2-0.3-0.3-0.10.1-0.7-0.3-0.3-0.5-0.3-0.4-0.5-0.4-0.8-0.6
Delta time in open arm before/after self-admin0.20.20.7-0.0-0.3-0.0-0.4-0.3-0.70.8-0.2-0.20.5-0.30.10.20.20.80.0
Diff in mean of infusions in LGA sessions0.40.51.10.90.70.50.80.60.80.90.51.10.81.00.70.70.50.50.1
Delay discount exponential model param0.10.10.3-0.3-0.1-0.20.1-0.2-0.3-0.3-0.3-0.0-0.5-0.0-0.1-0.00.00.00.5
Extinction: sum of active levers before priming0.70.72.41.00.90.91.00.90.70.50.80.40.50.50.90.90.90.71.6
Active lever presses in extinction session 60.00.00.30.50.00.10.1-0.0-0.2-0.30.10.1-0.20.1-0.0-0.00.2-0.10.2
Bone: final force1.11.82.91.11.21.11.51.31.41.10.91.71.01.71.31.41.71.50.7
Bone: final moment0.50.81.50.70.70.81.00.80.80.70.61.10.61.10.90.91.21.10.4
Food consumed during 24 hour testing period0.10.20.5-0.3-0.4-0.50.0-0.4-0.3-0.7-0.70.1-0.7-0.0-0.3-0.3-0.2-0.3-0.3
Glucose1.21.93.61.61.21.71.21.30.81.91.81.11.71.11.51.41.31.50.2
Heart weight0.00.00.1-0.10.00.1-0.20.10.1-0.00.2-0.40.1-0.30.0-0.0-0.10.10.2
Delay discount hyperbolic model param0.10.10.4-0.4-0.2-0.30.0-0.3-0.3-0.5-0.4-0.1-0.6-0.1-0.1-0.1-0.0-0.10.5
Intermittent access intake day 1-15 change1.22.43.61.91.61.81.81.61.21.51.81.41.51.31.61.61.51.41.3
Intermittent access intake escalation1.32.63.92.01.61.81.81.71.31.61.91.41.61.41.71.61.51.41.2
Intermittent access intake escalation 21.11.22.51.41.11.31.21.10.81.21.60.81.20.81.11.01.00.90.9
Intermitt. access day 1 inactive lever presses0.00.10.50.40.20.3-0.00.30.2-0.10.4-0.30.0-0.20.0-0.2-0.6-0.70.7
Intermitt. access day 15 inactive lever presses0.10.20.90.30.20.2-0.10.20.21.00.60.30.90.40.30.30.20.80.0
Intermitt. access escalation Index0.40.51.7-0.6-0.7-0.5-0.6-0.6-0.9-0.6-0.9-0.6-0.7-0.6-0.6-0.7-0.7-0.7-1.3
Intermittent access day 1 total infusions0.10.20.90.30.50.4-0.10.50.6-0.50.2-0.6-0.1-0.3-0.0-0.2-0.4-0.81.0
Intermittent access day 15 total infusions1.52.33.71.91.81.91.41.81.61.11.90.71.40.91.51.31.20.91.9
Intermittent access terminal intake (last 3 days)2.73.65.62.22.22.21.82.22.01.62.41.21.81.41.81.71.61.42.2
Intermittent access total infusions2.32.74.11.92.02.01.62.02.01.22.00.91.51.21.51.41.41.12.0
Intermittent access day 1 locomotion1.62.13.8-1.1-1.2-1.1-1.7-1.1-1.1-1.8-1.3-2.0-1.4-1.7-1.4-1.6-1.6-1.8-0.3
Intermittent access day 15 total locomotion0.40.62.0-0.4-0.6-0.4-1.1-0.6-0.8-0.6-0.1-1.4-0.5-1.3-0.8-0.9-1.0-0.80.3
Intermittent access total locomotion0.20.31.3-0.1-0.2-0.1-0.8-0.2-0.2-0.40.1-1.1-0.2-0.9-0.4-0.5-0.5-0.50.7
Intermittent access standard deviation0.10.30.7-0.4-0.4-0.5-0.7-0.6-0.6-0.30.2-0.8-0.4-0.8-0.6-0.6-0.6-0.40.3
Left kidney weight1.67.511.22.42.72.63.02.62.92.92.53.32.73.22.92.92.42.91.1
Right kidney weight1.77.911.72.42.82.63.12.63.02.82.63.42.73.22.93.02.63.11.4
Cocaine induced anxiety2.94.15.8-2.2-2.1-2.1-2.2-2.0-1.9-1.8-1.9-2.4-1.8-2.3-2.1-2.1-2.2-2.2-0.7
Post-drug Anxiety0.80.81.7-0.8-1.0-0.9-1.1-0.8-0.8-0.5-0.6-1.3-0.5-1.2-0.9-1.0-1.2-1.1-0.5
Baseline Anxiety1.61.93.01.71.51.51.41.41.31.31.71.31.41.31.41.31.21.10.2
Tail length0.00.10.60.00.40.20.30.30.7-0.8-0.20.3-0.50.40.0-0.0-0.1-0.20.0
Length with tail0.10.41.5-0.8-0.4-0.6-0.3-0.5-0.1-1.2-0.8-0.2-1.1-0.3-0.6-0.6-0.7-0.6-0.6
Length without tail0.51.52.2-1.3-1.3-1.3-1.0-1.2-1.1-1.4-1.3-1.2-1.5-1.2-1.2-1.2-1.3-1.2-0.5
Times rat made contact with spout1.31.41.8-1.0-1.2-1.3-1.0-1.2-1.2-1.3-1.3-0.9-1.3-0.9-1.3-1.3-1.2-1.3-1.3
Lifetime Intake1.82.23.51.71.81.81.51.81.91.01.80.91.31.11.41.31.41.01.6
Liver weight, left0.30.51.2-0.6-0.7-0.7-0.5-0.7-0.7-0.6-0.7-0.3-0.6-0.5-0.6-0.7-1.0-0.8-1.1
Liver weight, right0.40.71.6-0.7-0.6-0.9-0.5-0.7-0.3-1.2-1.0-0.7-1.1-0.7-0.8-0.9-1.1-1.3-0.4
Locomotor activity2.33.64.8-2.1-2.1-2.2-1.9-2.1-1.9-2.0-2.1-1.8-2.0-1.8-2.0-1.9-1.6-1.5-0.7
Locomotor testing distance1.93.44.5-2.0-1.9-2.0-1.9-1.9-1.7-2.1-2.0-1.9-2.0-1.8-2.0-1.9-1.6-1.8-0.5
Locomotor testing rearing0.20.40.8-0.9-0.6-0.8-0.6-0.7-0.5-0.7-0.8-0.6-0.7-0.6-0.6-0.5-0.1-0.10.1
Locomotion in novel chamber2.32.94.2-2.1-1.7-1.7-2.0-1.7-1.8-1.5-1.9-1.8-1.6-1.7-1.8-1.8-1.6-1.6-0.7
Locomotion in novel chamber post-restriction1.62.64.9-1.6-1.6-1.6-1.5-1.5-1.3-2.2-1.7-1.7-2.0-1.7-1.7-1.6-1.3-1.7-1.0
Fecal boli incidents, locomotor time 10.91.32.6-1.2-1.1-0.8-0.4-1.1-1.2-1.6-1.2-0.8-1.6-1.0-1.0-1.1-1.1-1.5-0.7
Change in fecal boli incidents, locomotor task0.40.41.01.00.70.60.50.70.41.00.80.40.90.30.70.60.10.30.6
Time >=10cm from walls, locomotor time 10.50.51.5-0.4-0.5-0.5-0.3-0.5-0.6-1.0-0.8-0.7-0.9-0.9-0.6-0.7-0.8-1.2-0.5
Bouts of movement, locomotor time 10.20.20.90.1-0.2-0.1-0.3-0.2-0.3-0.6-0.2-0.7-0.5-0.5-0.4-0.5-0.8-1.00.0
Total resting periods, locomotor time 10.10.10.40.40.10.2-0.10.1-0.1-0.20.1-0.4-0.2-0.3-0.1-0.2-0.5-0.60.1
Rest time, locomotor task time 10.10.10.50.30.40.50.00.40.10.10.4-0.30.1-0.10.1-0.1-0.5-0.70.6
Distance moved, locomotor task time 10.10.10.3-0.6-0.3-0.5-0.3-0.4-0.3-0.1-0.1-0.3-0.1-0.4-0.3-0.20.20.3-0.3
Vertical activity count, locomotor time 10.30.61.2-1.1-0.9-1.1-0.6-1.0-0.8-0.9-0.8-0.6-0.9-0.6-0.8-0.60.10.0-1.0
Time >=10cm from walls, locomotor time 20.20.31.01.00.70.50.80.60.50.50.40.40.40.20.60.60.70.30.6
Bouts of movement, locomotor time 20.50.91.41.01.01.00.91.01.20.90.90.91.01.00.90.90.80.80.4
Total resting periods, locomotor time 20.61.11.51.21.11.11.11.21.21.11.11.11.21.21.11.00.90.90.4
Rest time, locomotor task time 20.50.61.21.10.91.11.00.90.60.60.80.60.50.70.80.70.40.20.6
Distance moved, locomotor task time 20.60.71.5-0.9-0.9-1.2-1.2-1.1-0.9-0.4-0.9-1.0-0.5-1.1-0.8-0.6-0.20.1-0.4
Vertical activity count, locomotor time 20.91.22.2-1.3-1.3-1.5-1.2-1.3-1.1-1.0-1.2-1.1-1.0-1.1-1.1-0.9-0.5-0.4-1.0
Light reinforcement 11.84.57.2-2.4-2.3-2.7-2.1-2.4-2.0-2.3-2.4-1.6-2.4-1.7-2.2-2.1-1.7-1.7-1.4
Light reinforcement 22.03.14.3-1.7-2.0-2.1-1.9-2.1-2.0-1.5-1.5-1.4-1.7-1.5-1.9-1.8-1.5-1.4-1.8
Bone: marrow area0.00.00.1-0.2-0.3-0.2-0.1-0.3-0.3-0.2-0.2-0.1-0.3-0.0-0.2-0.10.20.2-0.2
Bone: maximum diameter0.30.61.0-0.9-0.9-0.9-0.7-0.8-0.7-0.9-1.0-0.6-0.9-0.6-0.8-0.7-0.3-0.40.1
Bone: maximum force0.30.61.30.60.70.60.70.60.70.80.61.00.70.90.70.81.01.10.1
Bone: maximum moment0.10.10.50.20.10.20.20.20.20.30.20.40.30.40.20.30.50.7-0.3
Mean time between licks in bursts0.00.10.6-0.1-0.1-0.1-0.2-0.2-0.10.40.30.00.30.1-0.00.10.40.8-0.3
Mean num. licks in bursts0.10.10.60.10.10.10.30.10.2-0.1-0.00.2-0.10.30.10.30.80.5-0.0
Cd content in liver0.10.10.60.10.40.30.10.30.50.30.40.20.40.10.20.30.40.70.8
Co content in liver0.10.20.70.30.30.30.30.20.30.20.20.10.20.10.30.40.80.80.6
Cu content in liver1.01.12.51.11.31.11.21.21.60.80.91.10.91.11.11.11.00.80.6
Fe content in liver2.02.43.1-1.4-1.6-1.6-1.4-1.6-1.6-1.7-1.7-1.5-1.8-1.6-1.6-1.5-1.2-1.6-1.1
K content in liver0.10.10.60.50.20.40.30.30.10.30.3-0.00.3-0.10.30.30.20.00.8
Mg content in liver0.50.51.2-0.5-0.7-0.6-0.6-0.6-0.7-0.8-0.6-0.9-0.7-0.9-0.7-0.8-0.9-1.1-0.3
Mn content in liver0.80.91.2-0.8-1.0-0.9-1.1-0.9-1.1-0.7-0.7-1.1-0.7-1.0-0.9-1.0-1.1-0.8-1.0
Na content in liver0.20.21.00.2-0.50.0-0.2-0.2-1.00.2-0.0-0.70.0-1.0-0.0-0.10.0-0.20.2
Rb content in liver0.40.41.70.61.00.60.50.81.30.20.60.50.40.90.50.50.40.30.1
Se content in liver0.30.42.00.20.50.20.40.40.70.30.30.60.30.60.40.61.31.4-0.4
Sr content in liver1.00.81.2-1.0-0.9-1.0-0.9-0.9-0.7-1.0-1.0-0.5-1.0-0.4-1.0-1.0-1.0-1.0-1.1
Zn content in liver2.32.54.41.51.71.41.61.61.81.31.41.41.41.21.61.72.11.81.7
Bone: minimum diameter0.10.20.4-0.6-0.5-0.5-0.4-0.4-0.4-0.6-0.6-0.4-0.6-0.3-0.4-0.30.10.20.0
Time in familiar zone, hab. session 10.30.30.7-0.5-0.5-0.3-0.8-0.5-0.7-0.3-0.3-0.8-0.4-0.7-0.5-0.5-0.40.2-0.5
Time in novel zone, hab. session 10.20.20.40.50.50.30.60.40.50.30.30.60.40.50.50.50.60.10.4
Total zone transitions, hab. session 10.91.32.8-1.0-1.0-1.1-1.0-1.0-0.9-1.4-1.3-1.0-1.4-0.9-1.1-1.2-1.4-1.7-0.4
Total locomotion distance, hab. session 11.01.52.5-1.1-1.2-1.3-1.0-1.2-1.0-1.5-1.5-0.9-1.5-0.9-1.2-1.2-1.2-1.6-0.5
Locomotion velocity, hab. session 11.31.93.9-1.3-1.3-1.5-1.1-1.3-1.1-1.8-1.7-1.0-1.7-1.0-1.4-1.4-1.6-2.0-0.5
Time in familiar zone, hab. session 20.91.02.1-1.0-1.0-1.0-1.4-1.0-1.1-0.7-0.7-1.3-0.7-1.2-1.0-1.0-0.6-0.5-0.7
Time in novel zone, hab. session 24.14.25.42.32.22.12.32.22.11.92.02.12.02.02.22.22.01.81.1
Total zone transitions, hab. session 22.12.75.7-1.7-1.5-1.6-1.3-1.5-1.4-2.0-1.8-1.2-1.9-1.2-1.7-1.7-2.1-2.4-0.6
Total locomotion distance, hab. session 21.01.42.5-1.3-1.1-1.2-0.9-1.1-0.9-1.6-1.4-0.8-1.5-0.8-1.2-1.2-1.2-1.5-0.2
Locomotion velocity, hab. session 21.01.32.6-1.3-1.1-1.2-0.8-1.1-0.8-1.5-1.4-0.6-1.5-0.6-1.1-1.2-1.3-1.6-0.2
Novel to familiar place preference ratio1.71.93.51.71.41.41.01.41.21.91.71.11.81.11.41.31.01.40.2
Novelty place preference2.72.94.92.11.81.71.31.81.62.22.11.42.21.41.71.71.31.70.5
Time in novel zone, NPP test2.52.74.52.01.71.71.21.71.52.12.01.32.11.31.71.61.41.70.5
Total zone transitions, NPP test1.72.54.0-1.6-1.5-1.6-1.3-1.6-1.4-1.9-1.7-1.2-1.9-1.2-1.6-1.6-1.8-2.0-0.7
Total locomotion distance, NPP test0.81.12.1-1.0-1.0-1.2-0.6-1.1-0.8-1.5-1.3-0.5-1.4-0.6-1.0-1.0-1.1-1.4-0.4
Locomotion velocity, NPP test0.60.91.8-1.0-0.9-1.1-0.5-1.0-0.7-1.3-1.2-0.4-1.3-0.5-0.9-0.9-1.0-1.3-0.3
Intraocular pressure0.71.01.90.50.90.81.00.91.40.70.91.20.81.30.91.01.21.30.9
Delta distance traveled before/after self-admin0.30.30.70.60.70.70.50.80.80.30.80.20.40.40.60.40.1-0.10.6
Delta ambulatory time before/after self-admin0.60.71.40.91.11.10.91.11.10.51.20.40.70.50.80.60.3-0.11.1
Parametrial fat weight6.715.818.4-4.0-4.1-4.0-4.0-4.1-4.3-4.1-4.0-4.1-4.1-4.1-4.1-4.1-3.9-3.6-2.9
Pavlov. Cond. lever latency0.10.10.4-0.2-0.2-0.2-0.5-0.2-0.4-0.1-0.0-0.6-0.1-0.6-0.3-0.3-0.10.1-0.4
Pavlov. Cond. magazine entry latency0.91.12.50.60.90.81.41.01.10.60.51.60.61.61.01.11.30.80.9
Pavlov. Cond. change in total contacts0.80.91.70.70.91.01.00.91.00.90.91.30.91.31.00.90.70.70.4
Pavlov. Cond. index score0.60.72.10.50.70.61.20.81.00.50.41.50.51.40.80.80.70.30.8
Pavlov. Cond. latency score0.50.61.70.40.60.51.10.70.90.40.31.30.41.30.70.70.60.30.8
Pavlov. Cond. lever contacts0.60.71.40.70.80.81.10.81.00.60.61.20.61.20.80.80.60.40.8
Pavlov. Cond. magazine entry number0.91.12.3-0.8-1.0-0.9-1.4-1.0-1.1-0.7-0.6-1.5-0.7-1.5-1.1-1.1-1.3-0.9-0.8
Pavlov. Cond. intertrial magazine entries0.10.20.3-0.3-0.4-0.4-0.5-0.4-0.4-0.4-0.4-0.5-0.4-0.5-0.4-0.20.40.4-0.3
Pavlov. Cond. lever-magazine prob. diff.0.60.72.20.50.80.71.20.81.00.60.41.50.51.40.80.80.70.40.7
Pavlov. Cond. response bias0.40.51.40.50.70.61.10.70.80.40.31.20.41.10.70.70.70.30.6
Pavlov. Cond. lever latency1.41.92.9-1.4-1.3-1.3-1.7-1.4-1.4-1.3-1.3-1.7-1.2-1.6-1.4-1.5-1.3-1.3-0.7
Pavlov. Cond. magazine entry latency3.94.86.02.22.12.12.22.12.22.22.12.42.12.42.22.22.32.31.5
Pavlov. Cond. change in total contacts2.23.55.71.51.71.72.11.71.91.81.72.41.72.31.92.02.12.20.6
Pavlov. Cond. index score3.75.06.92.22.22.12.52.22.32.22.12.62.12.62.32.32.32.21.3
Pavlov. Cond. latency score3.74.86.72.22.22.12.42.22.32.22.12.62.12.52.22.32.12.11.3
Pavlov. Cond. lever contacts1.92.64.11.61.51.52.01.61.71.51.42.01.41.91.61.71.61.50.7
Pavlov. Cond. magazine entry number5.97.39.0-2.7-2.6-2.6-2.8-2.6-2.7-2.8-2.6-3.0-2.7-3.0-2.7-2.8-2.9-2.9-1.6
Pavlov. Cond. intertrial magazine entries4.26.48.8-3.0-2.6-2.7-2.3-2.6-2.5-2.9-2.9-2.4-2.9-2.4-2.6-2.5-2.0-2.3-1.1
Pavlov. Cond. lever-magazine prob. diff.4.25.67.32.42.32.32.62.32.42.32.22.72.22.62.42.52.52.41.4
Pavlov. Cond. response bias3.44.76.62.12.12.02.52.12.22.11.92.62.02.52.22.32.42.31.1
Time in closed arm before self-admin3.34.26.7-2.0-2.1-1.9-1.9-2.0-2.2-2.1-1.9-2.1-2.2-2.0-2.0-2.1-2.6-2.4-0.3
Time in closed arm after self-admin3.63.86.6-2.0-1.9-1.9-2.0-1.9-1.8-1.7-2.0-1.7-1.7-1.8-2.0-2.1-2.6-2.4-1.4
Time in open arm before self-admin2.52.84.41.51.61.31.81.51.91.71.32.11.61.91.61.72.11.90.2
Time in open arm after self-admin0.91.03.40.90.70.70.80.60.41.30.60.91.00.81.01.21.61.80.3
Bone: periosteal estimation0.10.30.6-0.7-0.7-0.7-0.5-0.7-0.6-0.6-0.8-0.3-0.7-0.3-0.6-0.40.10.2-0.4
Bone: periosteal perimeter0.50.81.5-1.1-0.9-1.2-0.8-1.0-0.7-1.1-1.2-0.6-1.2-0.5-1.0-0.8-0.5-0.5-0.4
Bone: post-yield work0.71.01.6-1.0-0.9-1.0-1.2-0.9-1.0-0.7-0.9-1.1-0.7-1.1-1.0-1.0-1.1-0.9-1.0
Progressive ratio test 1 active lever presses3.24.06.32.22.32.12.12.32.51.41.71.91.72.12.02.02.21.71.7
Progressive ratio test 1 breakpoint2.93.55.92.02.12.02.02.22.41.31.61.81.61.91.91.82.11.61.6
Progressive ratio test 1 inactive lever presses0.10.10.40.40.30.40.10.40.2-0.20.3-0.10.0-0.00.20.0-0.0-0.30.6
Progressive ratio test 2 active lever presses2.12.53.91.91.91.91.82.01.90.91.61.11.21.21.51.41.50.81.8
Progressive ratio test 2 breakpoint2.32.64.01.92.02.01.82.01.91.01.71.11.31.31.61.41.50.91.8
Progressive ratio test 2 inactive lever presses0.10.10.40.40.30.4-0.00.50.40.30.4-0.20.5-0.10.20.20.30.30.6
Incentive Sensitization - Responses0.60.92.11.21.21.31.21.21.00.41.00.40.60.50.80.70.50.01.5
Incentive Sensitization - Breakpoint0.81.02.41.31.31.41.21.31.10.41.20.40.70.60.90.70.60.01.5
Sum of active levers in priming session hrs 5-60.30.30.50.60.60.40.20.50.60.60.20.40.60.50.50.50.60.70.5
Progressive ratio0.20.31.2-0.50.1-0.4-0.0-0.00.60.7-0.21.10.50.90.10.20.20.8-0.7
Food seeking constrained by brief footshock1.51.93.00.91.31.41.61.21.11.71.41.71.51.51.41.51.21.40.9
Seeking ratio, punishment vs. effort0.40.51.41.00.71.21.00.80.20.61.00.20.60.20.90.80.50.40.9
Retroperitoneal fat weight6.126.130.9-5.4-5.5-5.3-5.6-5.4-5.4-5.1-5.1-5.2-5.1-5.2-5.4-5.2-4.7-4.3-3.6
Reaction time number correct1.02.03.01.71.71.41.51.61.61.01.21.11.21.21.41.41.41.01.6
Reaction time mean minus median0.71.72.81.01.41.11.21.11.51.41.01.61.41.71.21.31.31.51.2
Reaction time mean minus median AUC0.61.52.80.81.40.91.21.01.61.20.81.61.21.71.11.21.21.41.0
Reaction time num false alarms0.10.10.30.50.50.40.10.50.50.50.5-0.10.50.00.30.2-0.00.10.3
Reaction time num false alarms AUC0.00.10.20.10.20.0-0.10.10.1-0.1-0.0-0.4-0.0-0.3-0.1-0.2-0.4-0.40.4
Reaction time trials correct on left1.02.03.01.71.71.41.51.61.61.01.21.11.21.21.41.41.41.01.6
Reaction time trials on left1.12.13.11.81.71.41.61.61.71.01.21.21.21.31.51.41.51.01.7
Reaction time mean0.10.21.0-0.20.1-0.0-0.2-0.10.20.90.30.50.80.50.20.30.21.00.0
Reaction time mean AUC0.20.41.40.10.40.30.10.20.51.20.50.61.00.60.40.50.31.10.1
Median of all reaction times0.10.20.4-0.6-0.3-0.4-0.6-0.4-0.20.6-0.00.00.4-0.0-0.2-0.1-0.30.6-0.4
Reaction time omissions0.10.10.2-0.10.3-0.20.3-0.00.3-0.4-0.20.5-0.30.5-0.1-0.00.2-0.1-0.1
Reaction time false alarm rate0.40.61.0-0.8-0.6-0.6-0.9-0.7-0.7-0.6-0.6-1.0-0.6-0.9-0.8-0.8-1.0-0.8-0.4
Reaction time premature initiation rate1.31.82.81.21.11.21.51.21.11.51.21.71.31.61.41.51.51.60.4
Reaction time premature initiations2.34.15.22.21.92.02.32.01.92.01.82.21.92.22.12.22.22.11.3
Std. dev. reaction times0.30.51.30.20.60.50.40.40.71.00.50.80.90.80.50.70.61.10.8
Reaction time trials completed1.12.13.11.81.71.41.61.61.71.01.21.21.21.31.51.41.51.01.7
Reaction time trials AUC1.12.13.11.71.71.41.61.61.71.11.21.21.21.31.51.51.51.11.6
Run reversals in cocaine runway, females1.81.82.9-1.2-1.4-1.2-1.1-1.4-1.7-1.5-1.6-1.5-1.6-1.6-1.3-1.2-1.0-1.00.4
Run reversals in cocaine runway, males0.40.41.1-0.6-0.5-0.5-0.1-0.6-0.8-1.0-0.6-0.4-1.0-0.5-0.6-0.5-0.3-0.7-0.2
Latency to leave start box in cocaine runway0.10.10.30.40.20.40.20.30.00.50.3-0.20.4-0.00.40.40.20.40.5
Latency to leave start box in cocaine runway, F0.70.81.61.31.11.30.81.10.61.01.00.11.00.31.00.90.70.61.2
Latency to leave start box in cocaine runway, M1.00.92.0-1.4-1.3-1.3-1.1-1.2-1.0-0.6-1.1-0.6-0.8-0.5-0.9-0.8-0.9-0.2-0.9
Std. dev. time between licks in bursts1.52.03.3-1.5-1.6-1.8-1.4-1.6-1.5-1.4-1.5-1.2-1.5-1.3-1.5-1.4-1.1-1.1-1.1
Total sessions with >9 infusions1.62.03.71.41.61.61.51.61.70.71.21.21.01.31.41.41.91.41.3
Short access day 1 total inactive lever presses0.00.00.1-0.0-0.00.1-0.20.00.0-0.20.4-0.4-0.1-0.3-0.1-0.10.30.30.2
Short access day 10 total inactive lever presses0.10.30.7-0.5-0.5-0.5-0.6-0.5-0.6-0.6-0.2-0.6-0.5-0.6-0.6-0.7-0.8-0.8-0.2
Short access day 1 total infusions0.40.51.00.81.01.00.80.90.90.00.80.30.30.40.60.50.80.30.7
Short access day 10 total infusions0.40.51.20.81.00.90.60.91.1-0.00.80.10.40.40.50.40.50.10.9
Short access total infusions1.82.33.91.71.91.81.61.92.00.81.51.11.21.41.51.41.71.11.1
Short access day 1 locomotion0.20.30.70.70.50.60.80.50.1-0.10.40.40.10.40.50.50.70.20.6
Short access day 10 total locomotion1.52.94.9-1.7-1.7-1.6-2.2-1.6-1.4-1.9-1.5-2.2-1.6-1.9-1.8-1.8-1.5-1.4-0.7
Short access total locomotion0.40.41.1-0.6-0.5-0.4-1.0-0.5-0.4-1.0-0.6-1.0-0.7-0.8-0.7-0.7-0.4-0.5-0.2
One hour access (0.3 mA shock)1.21.42.71.31.41.41.31.41.60.71.40.71.01.01.00.90.80.31.6
Compulsive drug intake0.10.10.3-0.5-0.5-0.5-0.2-0.5-0.5-0.1-0.20.1-0.3-0.1-0.3-0.2-0.10.0-0.5
One hour access (shock baseline)0.91.43.31.51.61.51.11.51.60.61.40.41.00.71.00.80.70.21.8
Social response proportion0.60.71.21.11.01.10.71.01.00.81.00.50.90.60.80.70.80.60.8
Social responses0.00.00.30.30.20.20.20.20.2-0.1-0.10.1-0.00.10.10.20.40.10.5
Social time0.10.10.70.20.50.40.10.30.5-0.10.2-0.20.10.00.20.20.60.50.8
Soleus weight0.20.51.2-0.8-1.0-0.6-0.7-0.9-1.1-0.5-0.7-0.4-0.7-0.5-0.7-0.6-0.5-0.2-0.7
Bone: stiffness3.45.68.12.02.52.22.52.32.52.32.12.92.32.82.42.42.32.51.3
Tibialis anterior weight0.41.33.40.81.30.91.51.11.80.40.71.60.51.61.01.11.00.70.9
Time to tail flick, vehicle, before self-admin0.50.50.90.80.80.90.90.80.50.70.90.60.70.60.70.70.70.30.7
Time to tail flick, vehicle, after self-admin0.81.02.0-1.0-0.8-0.9-1.0-0.8-0.6-1.4-0.7-1.4-1.2-1.2-1.1-1.2-0.8-1.30.1
Time to tail flick, test, before self-admin2.82.94.8-1.9-1.6-1.5-1.5-1.5-1.1-2.1-1.5-1.6-1.9-1.5-1.8-1.9-2.2-2.2-1.2
Time to tail flick, test, after self-admin0.10.10.6-0.0-0.0-0.1-0.20.10.4-0.8-0.1-0.2-0.50.1-0.2-0.20.0-0.1-0.2
Delta time to tail flick, vehicle, before/after SA0.80.72.5-0.9-0.7-0.9-0.8-0.6-0.1-1.6-0.7-1.2-1.3-0.9-0.9-0.9-0.3-0.70.2
Delta time to tail flick, test, before/after SA1.41.42.81.31.11.01.11.11.11.11.01.31.11.31.21.31.71.60.3
Tibia length0.00.10.3-0.00.20.20.40.30.20.10.20.40.00.50.20.20.10.20.3
Ambulatory time before self-admin1.01.53.6-1.2-1.6-1.5-1.4-1.7-1.9-0.0-1.7-0.2-0.6-0.7-1.1-0.8-0.50.4-1.8
Ambulatory time after self-admin0.40.52.1-0.4-0.9-0.7-0.7-0.9-1.20.3-0.8-0.0-0.1-0.4-0.6-0.5-0.5-0.1-1.5
Bone: tissue strength0.20.20.60.8-0.10.5-0.20.3-0.20.60.7-0.30.6-0.30.20.1-0.00.2-0.7
Total heroin consumption0.91.02.71.61.01.20.91.00.51.11.10.71.10.81.01.00.90.70.8
Bone: trabecular number0.30.50.7-0.6-0.7-0.8-0.9-0.8-0.7-0.6-0.7-0.7-0.6-0.6-0.7-0.7-0.8-0.5-0.6
Bone: trabecular spacing0.00.10.2-0.2-0.2-0.1-0.1-0.1-0.2-0.5-0.3-0.3-0.4-0.3-0.2-0.2-0.1-0.20.0
Bone: trabecular thickness0.50.71.10.60.90.70.80.70.90.80.81.00.81.00.80.80.91.00.3
Bone: trabecular tissue density0.50.81.10.80.91.00.91.00.81.01.00.91.00.90.90.90.60.60.5
Water consumed over 24 hours0.30.40.7-0.4-0.5-0.6-0.3-0.5-0.5-0.8-0.7-0.2-0.8-0.3-0.6-0.6-0.8-0.9-0.7
Number of responses in last shaping day0.70.82.00.60.70.50.70.50.41.30.61.21.01.00.91.00.91.40.6