Hub : Genes

Crygc

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr9_66486750_66490303 0.1 0.06 1.2e-13 0.11 0.12 0.1 0.11 9.8e-12 8.1e-13 1.6e-11 1.1e-11
2 pVTA intron excision ratio chr9_66453498_66490303 0.18 0.09 6.6e-09 0.2 0.2 0.19 0.21 6.7e-09 3.1e-09 1.2e-08 1.7e-09
3 PL intron excision ratio chr9_66453498_66490303 0.03 0.02 2.1e-03 0 0.02 0.01 0.01 1.5e-01 2.0e-03 2.7e-02 2.6e-02
4 Brain intron excision ratio chr9_66453498_66490303 0.04 0.03 3.1e-04 0.03 0.03 0.02 0.02 5.8e-04 1.0e-03 9.0e-03 2.5e-03
5 Brain intron excision ratio chr9_66486750_66490303 0.13 0.07 2.3e-13 0.12 0.13 0.11 0.13 2.3e-11 2.0e-12 1.4e-10 2.7e-12
6 NAcc intron excision ratio chr9_66486750_66490303 0.06 0.05 2.1e-05 0.04 0.04 0.04 0.04 8.3e-06 2.5e-05 3.6e-05 4.0e-05
7 BLA intron excision ratio chr9_66484496_66490303 0.05 0.04 7.7e-03 0.03 0.02 -0 0.01 1.7e-02 3.3e-02 3.8e-01 9.1e-02
8 Brain intron excision ratio chr9_66484496_66490303 0.12 0.1 2.6e-05 0.01 0.04 0.03 0.03 1.8e-02 1.2e-04 3.5e-04 7.8e-04
9 pVTA intron excision ratio chr9_66486750_66490303 0.19 0.1 2.9e-09 0.2 0.21 0.17 0.19 3.9e-09 2.6e-09 7.3e-08 1.3e-08
10 BLA intron excision ratio chr9_66486750_66490303 0.16 0.1 4.6e-08 0.13 0.14 0.13 0.12 1.4e-07 7.6e-08 1.3e-07 4.3e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.10.10.30.3-0.4-0.20.40.1-0.50.50.20.30.3
Area under the delay curve0.10.10.2-0.40.40.3-0.4-0.20.3-0.30.0-0.2-0.2
BMI with tail8.427.230.1-5.55.45.3-5.5-5.25.0-5.05.0-5.2-5.1
BMI without tail3.98.110.4-3.23.13.0-3.1-2.82.5-2.52.7-2.8-2.6
Body weight0.31.32.0-1.21.21.1-1.4-1.11.2-1.20.9-1.1-1.1
Weight adjusted by age0.10.10.50.3-0.2-0.10.20.1-0.70.70.1-0.1-0.0
Bone surface0.20.41.30.6-0.6-0.50.50.4-1.11.1-0.20.40.5
Bone volume0.71.21.91.2-1.2-1.01.10.9-1.41.4-0.61.01.0
Breakpoint value in progressive ratio session0.70.81.71.0-1.0-0.80.80.7-1.31.3-0.40.60.6
Number of licking bursts0.20.20.4-0.40.30.5-0.2-0.50.4-0.40.6-0.5-0.5
Context. condit. distance diff. score1.01.22.0-0.90.71.1-0.7-1.21.4-1.41.4-0.9-1.0
Locomotion velocity, session 11.92.03.71.3-1.1-1.51.31.6-1.31.3-1.91.41.4
Locomotion distance, session 10.20.20.70.00.0-0.30.30.5-0.60.6-0.80.20.3
Locomotion velocity, session 20.10.10.2-0.10.2-0.1-0.00.2-0.40.4-0.40.00.2
Locomotion distance, session 20.10.10.4-0.40.60.2-0.3-0.0-0.10.1-0.4-0.4-0.3
Locomotion velocity, session 30.70.91.7-1.00.81.0-0.8-1.00.8-0.81.3-0.8-0.7
Locomotion distance, session 31.41.52.01.3-1.3-1.21.41.2-1.21.2-1.11.11.1
Stereotopy head waving bouts, day 32.42.83.4-1.81.81.8-1.7-1.71.6-1.61.7-1.6-1.5
Stereotopy head waving duration, day 33.03.64.7-2.22.02.0-2.0-1.91.7-1.72.0-1.7-1.5
Locomotion velocity, session 70.00.00.1-0.20.20.2-0.2-0.20.0-0.00.2-0.3-0.3
Locomotion distance, session 70.30.41.00.6-0.3-0.60.50.7-0.90.9-1.00.20.3
Stereotopy head waving bouts, day 70.40.50.8-0.70.50.7-0.5-0.70.9-0.90.9-0.5-0.5
Stereotopy head waving duration, day 72.22.74.0-1.71.41.7-1.5-1.71.8-1.82.0-1.4-1.4
Locomotion velocity, session 80.10.20.3-0.40.30.4-0.2-0.40.4-0.40.5-0.4-0.3
Locomotion distance, session 80.20.30.5-0.50.50.6-0.2-0.50.7-0.70.4-0.5-0.5
Degree of sensitization distance0.50.50.9-0.81.00.7-0.9-0.50.5-0.50.2-0.8-0.7
Degree of sensitization stereotypy0.70.81.2-0.80.70.9-0.7-0.91.1-1.11.0-0.7-0.7
Conditioned locomotion1.21.42.00.9-0.9-1.11.11.2-1.41.4-1.21.11.2
Cocaine response after cond. corrected1.31.42.10.9-0.9-1.11.11.3-1.21.2-1.41.31.4
Cocaine response after cond. not corrected1.82.02.81.2-1.3-1.41.41.5-1.31.3-1.51.61.7
Cocaine response before conditioning0.00.10.20.3-0.4-0.10.3-0.10.3-0.30.20.1-0.1
Saline control response0.81.11.7-1.31.31.1-1.2-1.00.8-0.81.0-1.0-0.9
Bone: connectivity density0.60.91.5-1.01.01.0-1.0-1.00.5-0.51.2-1.0-0.9
Bone: cortical apparent density3.03.94.8-2.02.12.0-2.1-2.01.7-1.71.8-2.2-2.2
Bone: cortical area0.81.21.71.3-1.1-1.21.11.1-1.31.3-1.10.80.8
Bone: cortical porosity8.89.611.23.3-3.4-3.13.33.0-2.82.8-2.83.23.1
Bone: cortical porosity10.211.112.73.5-3.6-3.43.53.3-3.13.1-3.13.53.3
Bone: cortical thickness0.20.30.60.7-0.4-0.60.40.5-0.80.8-0.60.10.1
Bone: cortical thickness2.02.33.61.5-1.5-1.51.41.4-1.91.9-1.21.31.4
Bone: cortical tissue density3.44.55.3-2.22.32.1-2.2-2.11.9-1.91.9-2.3-2.3
Condit. Reinf. active minus inactive responses1.01.11.41.2-1.2-1.11.11.0-1.01.0-0.81.11.0
Condit. Reinf. active-inactive response ratio0.10.10.20.4-0.4-0.30.40.2-0.10.1-0.10.30.2
Condit. Reinf. active responses1.62.02.61.5-1.5-1.41.31.3-1.61.6-1.11.31.3
Condit. Reinf. inactive responses1.21.42.41.2-1.0-1.21.01.2-1.51.5-1.20.91.0
Incentive salience index mean1.21.41.91.3-1.3-1.21.21.1-1.41.4-0.91.11.1
Condit. Reinf. lever presses0.91.12.41.1-1.0-1.00.90.9-1.51.5-0.70.80.8
Condit. Reinf. active minus inactive responses8.410.411.23.2-3.2-3.23.13.3-3.23.2-3.13.33.3
Condit. Reinf. active-inactive response ratio7.57.98.42.8-2.8-2.82.72.8-2.82.8-2.72.92.9
Condit. Reinf. active responses5.27.27.82.6-2.6-2.72.62.7-2.82.8-2.62.72.8
Condit. Reinf. inactive responses0.20.30.30.5-0.5-0.50.60.5-0.50.5-0.40.50.6
Condit. Reinf. lever presses0.91.31.51.0-1.1-1.11.11.1-1.21.2-1.01.21.2
Condit. Reinf. lever reinforcers received5.67.98.72.7-2.8-2.82.82.8-2.82.8-2.72.93.0
Conditioned reinforcement - actives0.20.20.5-0.50.50.4-0.5-0.40.7-0.70.2-0.5-0.4
Conditioned reinforcement - inactives2.32.63.91.7-1.6-1.71.51.7-1.51.5-2.01.51.5
Conditioned locomotion5.46.58.2-2.52.82.5-2.8-2.52.1-2.12.3-2.9-2.8
Patch foraging indifference point 0 sec0.71.21.6-1.11.11.0-1.1-1.01.3-1.30.8-1.1-1.1
Patch foraging indifference point AUC0.50.61.90.6-0.5-0.60.40.6-1.41.4-0.60.20.4
Delay disc. indifference point, 0s delay1.51.71.9-1.41.31.3-1.4-1.31.2-1.21.2-1.3-1.3
Delay disc. indifference point, 16s delay0.00.00.10.0-0.1-0.10.10.1-0.20.2-0.10.20.2
Delay disc. indifference point, 2s delay1.71.92.1-1.41.41.4-1.3-1.31.5-1.51.3-1.3-1.3
Delay disc. indifference point, 24s delay0.20.20.2-0.50.50.5-0.4-0.50.5-0.50.4-0.4-0.4
Delay disc. indifference point, 4s delay1.31.31.8-1.31.31.2-1.3-1.01.2-1.20.8-1.1-1.1
Delay disc. indifference point, 8s delay0.00.00.20.10.0-0.20.10.2-0.00.0-0.40.20.2
Indifference point function ln k2.12.95.0-1.71.51.7-1.4-1.72.2-2.21.7-1.2-1.3
Indifference point function log k2.12.95.0-1.71.51.7-1.4-1.72.2-2.21.7-1.2-1.3
Patch foraging total patch changes 0 sec0.71.11.7-1.01.01.0-1.0-0.91.3-1.30.8-0.9-1.0
Patch foraging total patch changes 12 sec0.10.10.60.3-0.1-0.1-0.00.0-0.80.80.0-0.3-0.2
Patch foraging total patch changes 18 sec0.40.50.9-0.80.80.7-0.8-0.70.3-0.30.5-1.0-0.9
Patch foraging total patch changes 24 sec0.10.10.3-0.00.10.0-0.1-0.0-0.50.5-0.0-0.3-0.2
Patch foraging total patch changes 6 sec0.91.31.6-1.21.21.2-1.3-1.10.9-0.91.0-1.2-1.1
Patch foraging time to switch 0 sec0.00.00.10.2-0.2-0.20.20.2-0.00.0-0.20.20.2
Patch foraging water rate 0 sec0.10.10.3-0.30.40.3-0.3-0.30.2-0.20.2-0.6-0.5
Patch foraging water rate 12 sec0.40.61.0-0.90.70.8-0.6-0.81.0-1.00.8-0.5-0.4
Patch foraging water rate 18 sec0.40.60.90.8-0.9-0.70.90.7-0.40.4-0.61.00.9
Patch foraging water rate 24 sec0.10.10.30.0-0.1-0.10.20.10.6-0.6-0.30.30.2
Patch foraging water rate 6 sec1.42.12.5-1.61.51.5-1.4-1.51.4-1.41.4-1.4-1.3
Seeking ratio, delayed vs. immediate footshock0.70.81.40.7-0.8-0.80.70.8-1.21.2-0.70.90.9
Distance traveled before self-admin3.53.85.41.9-1.9-1.81.91.8-2.32.3-1.61.81.9
Distance traveled after self-admin0.10.20.4-0.00.20.3-0.3-0.4-0.20.20.5-0.7-0.7
Extensor digitorum longus weight2.07.79.7-3.03.12.8-3.0-2.72.4-2.42.5-2.9-2.8
Bone: elastic displacement0.30.40.9-0.60.40.6-0.5-0.70.6-0.60.9-0.5-0.5
Bone: elastic work0.30.40.70.8-0.8-0.60.80.5-0.70.7-0.20.60.5
Bone: endosteal estimation1.53.23.61.9-1.9-1.81.81.7-1.91.9-1.61.71.7
Bone: endosteal perimeter0.51.01.51.1-1.2-1.01.21.0-0.80.8-0.81.11.1
Epididymis fat weight0.00.10.20.4-0.3-0.30.30.20.1-0.1-0.30.1-0.0
Delta time in closed arm before/after self-admin1.01.01.4-1.21.11.1-1.0-0.90.9-0.91.0-0.8-0.7
Delta time in open arm before/after self-admin3.53.33.81.9-1.9-1.81.81.8-1.91.9-1.71.81.7
Diff in mean of infusions in LGA sessions0.60.61.6-0.80.50.9-0.6-1.00.7-0.71.3-0.7-0.7
Delay discount exponential model param0.10.10.10.3-0.4-0.20.30.1-0.30.30.00.20.2
Extinction: sum of active levers before priming0.30.30.8-0.30.30.5-0.4-0.60.0-0.00.9-0.7-0.7
Active lever presses in extinction session 60.30.30.50.6-0.5-0.50.50.5-0.70.7-0.50.40.4
Bone: final force1.52.43.11.8-1.7-1.51.61.4-1.81.8-1.21.31.2
Bone: final moment1.01.62.11.4-1.4-1.31.31.1-1.41.4-1.01.11.0
Food consumed during 24 hour testing period0.60.71.10.8-0.8-0.80.70.9-1.01.0-0.80.80.9
Glucose0.81.21.4-1.11.11.1-1.2-1.10.9-0.91.2-1.2-1.2
Heart weight0.20.30.70.6-0.8-0.50.70.40.5-0.5-0.30.80.6
Delay discount hyperbolic model param0.20.20.30.5-0.6-0.40.50.3-0.50.5-0.10.40.4
Intermittent access intake day 1-15 change0.10.10.1-0.30.20.2-0.2-0.20.3-0.30.4-0.00.1
Intermittent access intake escalation0.00.00.2-0.20.10.2-0.1-0.20.2-0.20.40.10.2
Intermittent access intake escalation 20.00.00.2-0.0-0.1-0.10.10.1-0.10.10.20.30.5
Intermitt. access day 1 inactive lever presses0.10.10.30.5-0.4-0.40.40.3-0.20.2-0.60.20.1
Intermitt. access day 15 inactive lever presses0.80.81.20.9-1.1-0.91.00.9-0.80.8-0.71.01.0
Intermitt. access escalation Index2.72.44.6-1.51.51.6-1.6-1.70.5-0.52.1-1.7-1.6
Intermittent access day 1 total infusions0.00.00.0-0.10.20.1-0.2-0.0-0.10.1-0.1-0.1-0.1
Intermittent access day 15 total infusions0.30.30.5-0.60.60.6-0.6-0.60.4-0.40.7-0.5-0.5
Intermittent access terminal intake (last 3 days)0.60.70.9-0.90.80.8-0.8-0.80.8-0.80.9-0.7-0.6
Intermittent access total infusions0.00.00.0-0.10.20.1-0.2-0.0-0.10.1-0.0-0.2-0.1
Intermittent access day 1 locomotion0.00.10.20.10.20.0-0.2-0.1-0.10.1-0.1-0.4-0.5
Intermittent access day 15 total locomotion0.00.00.1-0.10.20.2-0.2-0.2-0.10.10.3-0.3-0.3
Intermittent access total locomotion0.40.51.0-0.60.80.6-0.9-0.70.3-0.30.5-1.0-1.0
Intermittent access standard deviation0.80.81.10.9-1.0-1.00.90.9-0.60.6-0.91.01.0
Left kidney weight0.00.10.2-0.20.20.3-0.4-0.40.5-0.50.4-0.3-0.4
Right kidney weight0.00.00.10.0-0.00.0-0.1-0.10.3-0.30.1-0.0-0.1
Cocaine induced anxiety0.70.81.5-1.00.80.9-0.8-0.91.2-1.20.9-0.6-0.6
Post-drug Anxiety0.80.81.4-1.00.90.9-0.8-0.91.2-1.20.9-0.7-0.7
Baseline Anxiety0.70.81.20.8-0.9-0.90.91.0-0.60.6-1.11.01.0
Tail length5.316.017.74.1-3.9-4.13.94.1-4.04.0-4.23.93.9
Length with tail5.821.423.44.8-4.7-4.84.64.7-4.24.2-4.84.74.6
Length without tail1.43.04.32.1-2.0-1.91.81.8-1.41.4-1.71.71.6
Times rat made contact with spout0.91.01.21.1-1.1-1.11.01.0-1.01.0-1.01.00.9
Lifetime Intake0.20.20.3-0.50.60.4-0.5-0.30.5-0.50.2-0.4-0.4
Liver weight, left1.93.03.71.6-1.6-1.71.51.8-1.91.9-1.61.81.9
Liver weight, right0.61.11.90.9-0.9-1.00.81.0-1.41.4-1.00.91.0
Locomotor activity0.00.00.00.1-0.2-0.10.20.00.2-0.2-0.10.0-0.0
Locomotor testing distance0.10.10.50.0-0.20.0-0.0-0.10.7-0.7-0.00.1-0.0
Locomotor testing rearing0.00.00.10.2-0.3-0.10.20.10.3-0.3-0.00.20.1
Locomotion in novel chamber2.02.54.5-1.61.61.7-1.6-1.80.8-0.82.1-1.7-1.6
Locomotion in novel chamber post-restriction0.10.10.3-0.10.20.2-0.3-0.3-0.10.10.3-0.5-0.5
Fecal boli incidents, locomotor time 11.51.61.91.3-1.4-1.31.31.2-1.31.3-1.11.31.2
Change in fecal boli incidents, locomotor task0.20.20.40.2-0.2-0.40.40.5-0.20.2-0.50.60.6
Time >=10cm from walls, locomotor time 12.82.93.91.7-1.6-1.81.61.8-1.61.6-2.01.71.7
Bouts of movement, locomotor time 12.12.33.51.4-1.3-1.61.41.7-1.41.4-1.91.51.6
Total resting periods, locomotor time 11.71.83.31.2-1.1-1.41.21.5-1.21.2-1.81.31.3
Rest time, locomotor task time 12.02.22.71.4-1.4-1.51.41.6-1.41.4-1.71.61.6
Distance moved, locomotor task time 10.91.01.7-0.80.90.9-1.0-1.01.0-1.00.8-1.2-1.3
Vertical activity count, locomotor time 11.71.72.4-1.21.21.3-1.2-1.41.3-1.31.5-1.4-1.4
Time >=10cm from walls, locomotor time 21.01.11.71.0-0.9-1.11.01.1-0.90.9-1.31.01.0
Bouts of movement, locomotor time 20.50.50.7-0.60.70.7-0.7-0.70.7-0.70.6-0.8-0.8
Total resting periods, locomotor time 20.10.10.2-0.10.20.1-0.2-0.20.3-0.30.1-0.3-0.4
Rest time, locomotor task time 22.12.43.41.4-1.3-1.61.51.7-1.41.4-1.81.71.7
Distance moved, locomotor task time 20.91.11.7-0.91.01.0-1.1-1.01.0-1.00.8-1.2-1.3
Vertical activity count, locomotor time 24.65.05.5-2.22.12.3-2.2-2.32.2-2.22.3-2.3-2.3
Light reinforcement 11.73.13.7-1.91.81.8-1.8-1.81.5-1.51.9-1.8-1.7
Light reinforcement 20.70.91.30.9-1.1-0.91.00.9-0.90.9-0.81.11.1
Bone: marrow area1.53.23.61.9-1.9-1.81.81.7-1.81.8-1.61.71.7
Bone: maximum diameter1.22.22.61.6-1.5-1.51.51.5-1.41.4-1.41.41.3
Bone: maximum force0.71.21.81.4-1.2-1.11.11.0-1.31.3-0.90.80.8
Bone: maximum moment0.40.61.01.0-0.9-0.80.80.7-0.90.9-0.60.60.5
Mean time between licks in bursts0.40.50.6-0.80.80.7-0.8-0.70.7-0.70.7-0.7-0.6
Mean num. licks in bursts0.50.60.90.8-0.7-0.80.50.8-0.70.7-0.90.70.7
Cd content in liver0.30.30.7-0.50.30.6-0.4-0.60.8-0.80.8-0.4-0.4
Co content in liver0.20.20.6-0.40.30.4-0.2-0.40.8-0.80.4-0.3-0.4
Cu content in liver0.00.00.10.3-0.3-0.10.1-0.0-0.10.10.1-0.1-0.2
Fe content in liver0.10.10.40.5-0.6-0.40.50.2-0.30.3-0.00.40.3
K content in liver0.30.30.5-0.60.70.5-0.7-0.4-0.10.10.4-0.6-0.4
Mg content in liver0.60.71.1-1.00.90.9-0.9-0.80.5-0.50.9-0.7-0.6
Mn content in liver2.12.43.2-1.81.51.6-1.6-1.51.7-1.71.6-1.2-1.1
Na content in liver0.40.41.40.3-0.3-0.40.20.4-1.21.2-0.00.40.5
Rb content in liver0.00.00.0-0.20.20.1-0.1-0.10.0-0.00.1-0.1-0.1
Se content in liver0.40.50.9-0.70.60.7-0.6-0.70.9-0.90.7-0.6-0.6
Sr content in liver0.10.10.20.2-0.1-0.30.20.4-0.50.5-0.40.30.3
Zn content in liver0.30.30.5-0.50.50.5-0.5-0.60.5-0.50.5-0.7-0.7
Bone: minimum diameter1.52.83.71.9-1.9-1.71.81.6-1.61.6-1.51.61.5
Time in familiar zone, hab. session 12.32.12.6-1.61.51.5-1.4-1.51.5-1.51.5-1.3-1.3
Time in novel zone, hab. session 16.96.77.02.6-2.6-2.62.52.6-2.62.6-2.42.62.6
Total zone transitions, hab. session 10.71.01.50.7-0.7-0.90.91.1-1.01.0-1.21.01.0
Total locomotion distance, hab. session 12.02.93.31.5-1.6-1.71.71.7-1.81.8-1.81.71.7
Locomotion velocity, hab. session 11.62.32.71.4-1.4-1.51.51.5-1.71.7-1.61.41.5
Time in familiar zone, hab. session 20.40.40.8-0.50.60.6-0.7-0.70.3-0.30.7-0.9-0.9
Time in novel zone, hab. session 20.20.20.60.2-0.4-0.40.50.50.1-0.1-0.50.80.7
Total zone transitions, hab. session 20.10.10.40.1-0.1-0.30.40.4-0.10.1-0.60.30.4
Total locomotion distance, hab. session 20.10.10.40.3-0.3-0.40.50.4-0.20.2-0.60.30.3
Locomotion velocity, hab. session 20.10.10.40.3-0.3-0.40.50.4-0.20.2-0.60.30.3
Novel to familiar place preference ratio1.61.62.21.1-1.1-1.31.21.4-1.21.2-1.51.31.4
Novelty place preference1.81.82.21.1-1.1-1.31.21.4-1.51.5-1.51.41.5
Time in novel zone, NPP test2.02.12.61.2-1.3-1.41.31.5-1.51.5-1.51.51.6
Total zone transitions, NPP test0.20.20.50.3-0.3-0.40.60.5-0.60.6-0.70.30.4
Total locomotion distance, NPP test0.60.81.40.7-0.7-0.80.91.0-1.01.0-1.20.70.8
Locomotion velocity, NPP test0.30.40.90.4-0.3-0.50.60.7-0.70.7-0.90.30.4
Intraocular pressure2.53.54.8-1.91.81.8-1.8-1.72.2-2.21.4-1.8-1.9
Delta distance traveled before/after self-admin3.33.64.4-1.71.81.9-1.8-2.01.8-1.82.1-2.0-2.1
Delta ambulatory time before/after self-admin2.73.03.7-1.51.61.7-1.6-1.81.6-1.61.9-1.9-1.9
Parametrial fat weight0.40.81.71.0-0.8-1.00.81.0-0.90.9-1.30.70.6
Pavlov. Cond. lever latency0.00.00.1-0.10.10.2-0.1-0.20.3-0.30.2-0.1-0.2
Pavlov. Cond. magazine entry latency0.50.61.01.0-0.9-0.80.80.7-0.80.8-0.60.60.5
Pavlov. Cond. change in total contacts0.10.10.2-0.20.30.2-0.4-0.30.2-0.20.2-0.3-0.4
Pavlov. Cond. index score0.30.40.70.7-0.7-0.70.60.6-0.80.8-0.50.60.6
Pavlov. Cond. latency score0.30.40.60.6-0.6-0.60.50.6-0.80.8-0.50.50.5
Pavlov. Cond. lever contacts0.10.10.30.2-0.2-0.20.10.3-0.50.5-0.20.20.2
Pavlov. Cond. magazine entry number0.40.50.7-0.80.80.8-0.7-0.70.5-0.50.8-0.6-0.6
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.20.10.00.00.1-0.10.1-0.10.20.2
Pavlov. Cond. lever-magazine prob. diff.0.40.50.70.8-0.7-0.70.60.6-0.90.9-0.50.60.6
Pavlov. Cond. response bias0.60.70.90.9-0.8-0.90.70.8-0.90.9-0.90.70.7
Pavlov. Cond. lever latency1.31.72.0-1.31.41.3-1.4-1.31.3-1.31.1-1.4-1.4
Pavlov. Cond. magazine entry latency0.20.30.40.6-0.6-0.60.50.5-0.60.6-0.40.50.4
Pavlov. Cond. change in total contacts1.52.02.41.4-1.4-1.41.41.5-1.31.3-1.41.51.6
Pavlov. Cond. index score1.82.42.51.6-1.6-1.51.61.5-1.61.6-1.41.61.6
Pavlov. Cond. latency score1.62.02.21.5-1.5-1.41.51.4-1.51.5-1.21.41.4
Pavlov. Cond. lever contacts2.43.33.71.8-1.9-1.81.91.8-1.71.7-1.61.91.9
Pavlov. Cond. magazine entry number0.60.81.2-1.00.90.9-0.8-0.81.1-1.10.6-0.8-0.8
Pavlov. Cond. intertrial magazine entries2.02.63.2-1.81.71.6-1.7-1.51.6-1.61.5-1.4-1.4
Pavlov. Cond. lever-magazine prob. diff.1.62.12.21.4-1.5-1.41.51.4-1.51.5-1.31.51.5
Pavlov. Cond. response bias2.33.13.41.8-1.8-1.71.81.7-1.81.8-1.61.81.8
Time in closed arm before self-admin1.31.52.21.5-1.5-1.31.41.1-1.11.1-0.91.11.0
Time in closed arm after self-admin0.10.10.10.4-0.4-0.30.40.2-0.10.1-0.20.30.2
Time in open arm before self-admin2.42.63.4-1.91.81.7-1.7-1.51.6-1.61.4-1.5-1.4
Time in open arm after self-admin1.11.21.91.1-1.0-1.10.91.1-1.41.4-1.10.90.9
Bone: periosteal estimation1.93.84.82.2-2.1-2.02.01.9-2.02.0-1.81.81.7
Bone: periosteal perimeter1.52.63.11.8-1.7-1.61.71.6-1.51.5-1.51.61.5
Bone: post-yield work0.00.00.10.3-0.2-0.10.1-0.00.3-0.3-0.1-0.1-0.3
Progressive ratio test 1 active lever presses0.20.20.4-0.30.50.4-0.5-0.4-0.20.20.5-0.6-0.6
Progressive ratio test 1 breakpoint0.20.20.3-0.20.40.3-0.4-0.4-0.30.30.5-0.5-0.5
Progressive ratio test 1 inactive lever presses1.31.41.9-1.11.21.2-1.2-1.21.1-1.11.1-1.3-1.4
Progressive ratio test 2 active lever presses0.10.10.1-0.30.30.2-0.3-0.20.2-0.20.2-0.3-0.2
Progressive ratio test 2 breakpoint0.00.00.0-0.00.1-0.0-0.10.00.0-0.0-0.0-0.00.0
Progressive ratio test 2 inactive lever presses0.10.10.2-0.20.30.3-0.4-0.30.1-0.10.3-0.5-0.5
Incentive Sensitization - Responses0.10.10.40.3-0.2-0.30.20.4-0.60.6-0.40.20.3
Incentive Sensitization - Breakpoint0.10.10.20.2-0.1-0.30.10.3-0.50.5-0.40.20.3
Sum of active levers in priming session hrs 5-60.60.51.40.8-0.7-0.60.60.5-1.21.2-0.40.30.4
Progressive ratio0.00.00.0-0.20.10.0-0.00.10.1-0.1-0.20.10.2
Food seeking constrained by brief footshock2.53.14.7-1.71.81.8-1.7-1.91.3-1.32.2-1.9-1.8
Seeking ratio, punishment vs. effort1.11.42.5-0.91.01.2-1.1-1.40.8-0.81.6-1.4-1.4
Retroperitoneal fat weight0.72.22.8-1.31.41.4-1.4-1.41.6-1.61.2-1.6-1.7
Reaction time number correct0.40.61.0-0.90.70.8-0.6-0.80.8-0.81.0-0.4-0.4
Reaction time mean minus median0.00.00.1-0.10.20.0-0.3-0.0-0.30.3-0.0-0.2-0.1
Reaction time mean minus median AUC0.10.10.50.1-0.0-0.30.10.3-0.70.7-0.30.30.4
Reaction time num false alarms3.95.35.6-2.32.32.3-2.3-2.32.2-2.22.3-2.4-2.4
Reaction time num false alarms AUC3.34.55.0-2.22.22.2-2.1-2.12.1-2.12.0-2.1-2.1
Reaction time trials correct on left0.40.61.0-0.90.70.8-0.6-0.80.8-0.81.0-0.4-0.4
Reaction time trials on left0.40.61.0-0.90.70.9-0.6-0.80.8-0.81.0-0.4-0.4
Reaction time mean3.44.75.22.3-2.2-2.32.12.2-2.22.2-2.22.12.1
Reaction time mean AUC2.63.54.02.0-1.9-2.01.81.9-1.91.9-1.91.81.8
Median of all reaction times5.06.97.82.8-2.7-2.72.62.6-2.52.5-2.62.62.5
Reaction time omissions0.10.10.3-0.20.10.1-0.1-0.10.6-0.6-0.00.1-0.0
Reaction time false alarm rate1.42.02.4-1.31.41.3-1.4-1.31.5-1.51.1-1.5-1.5
Reaction time premature initiation rate0.20.30.40.4-0.5-0.40.60.5-0.60.6-0.40.50.6
Reaction time premature initiations0.00.00.1-0.20.10.10.1-0.1-0.00.00.20.20.3
Std. dev. reaction times0.50.81.00.9-0.8-0.90.70.9-1.01.0-0.90.80.8
Reaction time trials completed0.40.61.0-0.90.70.9-0.6-0.80.8-0.81.0-0.4-0.4
Reaction time trials AUC0.30.40.7-0.80.60.7-0.5-0.60.6-0.60.8-0.3-0.2
Run reversals in cocaine runway, females0.60.61.4-0.70.70.6-0.7-0.51.2-1.20.2-0.6-0.7
Run reversals in cocaine runway, males0.30.30.40.6-0.6-0.60.70.5-0.40.4-0.50.60.5
Latency to leave start box in cocaine runway2.32.52.9-1.61.71.5-1.6-1.51.7-1.71.3-1.6-1.6
Latency to leave start box in cocaine runway, F1.81.92.6-1.31.41.3-1.3-1.31.6-1.61.1-1.4-1.5
Latency to leave start box in cocaine runway, M0.00.00.1-0.20.20.1-0.2-0.1-0.10.10.2-0.2-0.1
Std. dev. time between licks in bursts3.03.64.7-2.22.12.0-1.9-1.91.7-1.71.7-1.9-1.8
Total sessions with >9 infusions0.00.10.2-0.00.1-0.10.00.10.4-0.4-0.30.20.1
Short access day 1 total inactive lever presses0.10.10.3-0.20.40.3-0.4-0.4-0.10.10.3-0.5-0.6
Short access day 10 total inactive lever presses1.21.31.91.4-1.3-1.21.31.1-1.01.0-1.11.11.0
Short access day 1 total infusions0.30.30.4-0.60.60.6-0.6-0.60.6-0.60.6-0.5-0.5
Short access day 10 total infusions0.10.20.30.2-0.2-0.40.30.4-0.40.4-0.50.50.5
Short access total infusions0.50.50.9-0.80.80.6-0.7-0.61.0-1.00.3-0.6-0.6
Short access day 1 locomotion0.80.91.11.1-1.0-1.00.90.9-1.01.0-0.90.80.8
Short access day 10 total locomotion0.30.40.60.8-0.6-0.70.70.6-0.50.5-0.70.60.5
Short access total locomotion0.00.00.1-0.10.30.1-0.3-0.10.0-0.0-0.0-0.3-0.3
One hour access (0.3 mA shock)0.20.20.40.5-0.3-0.50.30.4-0.70.7-0.50.20.2
Compulsive drug intake0.20.20.50.6-0.4-0.50.40.5-0.40.4-0.70.30.2
One hour access (shock baseline)0.00.00.0-0.00.0-0.00.00.0-0.10.10.10.10.1
Social response proportion0.30.30.40.5-0.5-0.60.50.6-0.60.6-0.60.60.7
Social responses0.50.61.10.7-0.7-0.70.70.7-1.01.0-0.60.70.7
Social time0.30.40.60.5-0.6-0.50.60.5-0.70.7-0.30.70.8
Soleus weight0.10.20.4-0.50.60.3-0.6-0.2-0.40.40.1-0.4-0.2
Bone: stiffness0.60.91.41.1-1.0-1.00.90.9-1.21.2-0.80.70.7
Tibialis anterior weight0.51.72.4-1.51.61.4-1.5-1.30.8-0.81.3-1.4-1.3
Time to tail flick, vehicle, before self-admin0.20.20.3-0.40.50.4-0.5-0.50.2-0.20.4-0.5-0.6
Time to tail flick, vehicle, after self-admin0.80.91.31.0-1.0-1.01.11.0-0.50.5-1.11.11.0
Time to tail flick, test, before self-admin0.90.81.80.8-0.8-1.00.91.1-0.30.3-1.31.11.0
Time to tail flick, test, after self-admin2.62.73.4-1.71.91.7-1.7-1.61.4-1.41.5-1.8-1.8
Delta time to tail flick, vehicle, before/after SA0.00.00.10.1-0.2-0.10.20.10.3-0.3-0.10.20.2
Delta time to tail flick, test, before/after SA2.82.53.4-1.61.71.7-1.7-1.70.9-0.91.8-1.8-1.7
Tibia length1.74.85.72.4-2.2-2.32.22.2-2.12.1-2.42.12.0
Ambulatory time before self-admin1.41.52.91.1-1.1-1.11.11.1-1.71.7-0.91.01.1
Ambulatory time after self-admin1.82.03.3-1.11.31.4-1.4-1.60.7-0.71.7-1.8-1.8
Bone: tissue strength0.30.30.7-0.30.30.4-0.3-0.50.8-0.80.4-0.5-0.6
Total heroin consumption0.70.81.01.0-1.0-0.91.00.8-0.90.9-0.70.80.8
Bone: trabecular number0.30.41.1-0.60.50.7-0.6-0.80.3-0.31.1-0.7-0.6
Bone: trabecular spacing0.50.61.40.9-0.7-0.90.80.9-0.40.4-1.20.70.7
Bone: trabecular thickness0.30.30.40.6-0.7-0.50.60.4-0.70.7-0.30.50.5
Bone: trabecular tissue density0.91.32.81.3-1.1-1.31.11.3-0.80.8-1.70.90.8
Water consumed over 24 hours0.20.30.4-0.50.50.5-0.6-0.50.2-0.20.6-0.6-0.5
Number of responses in last shaping day0.60.61.00.9-1.0-0.81.00.8-0.40.4-0.80.90.8