Crebbp

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Crebbp 0.08 0.04 1.3e-06 0.04 0.04 0.04 0.03 3.9e-05 1.9e-05 1.9e-05 2.3e-04
2 Liver mRNA stability Crebbp 0.05 0.02 1.0e-06 0.06 0.04 0.05 0.06 2.0e-07 1.8e-05 5.5e-06 8.4e-07
3 OFC gene expression Crebbp 0.7 0.09 1.5e-13 0.48 0.41 0.42 0.44 3.2e-13 7.3e-11 4.1e-11 7.3e-12
4 BLA gene expression Crebbp 0.68 0.07 0.0e+00 0.54 0.51 0.51 0.56 3.5e-34 3.8e-31 3.1e-31 3.7e-35
5 Brain gene expression Crebbp 0.2 0.06 0.0e+00 0.23 0.23 0.25 0.25 7.3e-21 6.9e-21 1.1e-22 4.1e-23
6 pVTA gene expression Crebbp 0.46 0.11 0.0e+00 0.44 0.38 0.41 0.42 7.1e-21 3.3e-17 4.6e-19 5.7e-20
7 Adipose isoform ratio NM_133381.4 0.04 0.02 4.1e-04 0.01 0.02 0.01 0.01 4.4e-02 4.1e-03 3.1e-02 3.0e-02
8 PL gene expression Crebbp 0.36 0.07 0.0e+00 0.46 0.46 0.47 0.47 9.7e-57 1.1e-55 1.0e-57 2.5e-57
9 IL gene expression Crebbp 0.7 0.11 6.2e-10 0.34 0.26 0.25 0.3 6.8e-09 6.9e-07 9.1e-07 5.0e-08
10 OFC mRNA stability Crebbp 0.42 0.12 1.7e-05 0.13 0.12 0.09 0.08 5.9e-04 8.6e-04 4.1e-03 7.4e-03
11 PL mRNA stability Crebbp 0.06 0.02 6.9e-07 0.08 0.07 0.07 0.07 7.1e-09 5.6e-08 1.3e-08 1.4e-08
12 NAcc gene expression Crebbp 0.26 0.07 0.0e+00 0.3 0.27 0.29 0.3 1.7e-34 5.9e-31 2.6e-33 1.6e-34
13 Brain mRNA stability Crebbp 0.03 0.02 2.9e-03 0 0.01 0 0 1.3e-01 2.6e-02 2.0e-01 2.5e-01
14 NAcc mRNA stability Crebbp 0.12 0.05 3.5e-09 0.07 0.07 0.07 0.07 8.3e-09 8.7e-09 5.7e-09 1.9e-08
15 BLA mRNA stability Crebbp 0.13 0.06 3.9e-06 0.07 0.07 0.08 0.09 8.8e-05 1.3e-04 6.5e-05 1.1e-05
16 pVTA mRNA stability Crebbp 0.11 0.07 5.2e-03 0.02 0.02 -0 0 5.0e-02 3.7e-02 4.0e-01 3.0e-01
17 IL mRNA stability Crebbp 0.26 0.11 8.7e-04 0.08 0.06 0.08 0.09 6.6e-03 1.7e-02 6.6e-03 4.1e-03
18 LHb mRNA stability Crebbp 0.15 0.09 7.5e-03 0.12 0.08 0.09 0.1 8.9e-04 6.8e-03 4.2e-03 2.7e-03
19 LHb gene expression Crebbp 0.21 0.1 2.1e-03 0.06 0.07 0.02 0.03 1.8e-02 1.1e-02 1.2e-01 6.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.50.81.6-0.0-0.8-0.60.80.8-0.80.9-1.0-1.0-1.0-1.11.01.2-1.10.91.2-0.50.40.5
Area under the delay curve0.10.11.51.20.0-0.1-0.1-0.10.2-0.00.10.10.10.10.00.0-0.50.1-0.1-0.70.3-0.4
BMI with tail0.30.83.3-0.40.70.8-0.9-0.90.7-1.80.60.80.80.7-0.8-0.81.3-1.4-0.5-0.81.00.2
BMI without tail0.20.31.6-0.1-0.5-0.10.20.3-0.5-1.1-0.5-0.4-0.4-0.30.20.2-0.2-0.60.7-1.30.90.6
Body weight1.45.88.7-2.9-3.0-2.62.62.7-2.72.4-2.6-2.6-2.6-2.62.62.1-2.32.02.51.1-0.92.1
Weight adjusted by age2.52.85.81.92.41.7-2.0-1.81.9-1.41.91.81.81.7-1.7-1.31.7-1.4-1.4-1.01.0-1.3
Bone surface0.20.41.1-0.3-0.5-0.50.50.5-0.50.8-0.7-0.7-0.7-0.80.70.6-0.60.71.00.3-0.40.6
Bone volume0.20.40.90.1-0.5-0.40.50.5-0.50.6-0.6-0.7-0.7-0.70.70.8-0.70.61.0-0.50.40.3
Breakpoint value in progressive ratio session0.20.20.60.50.70.6-0.6-0.50.3-0.20.40.30.30.4-0.4-0.8-0.2-0.10.00.4-0.20.4
Number of licking bursts0.10.10.50.5-0.0-0.1-0.1-0.20.30.2-0.00.10.1-0.1-0.00.10.30.00.6-0.20.70.1
Context. condit. distance diff. score0.10.10.80.7-0.20.30.00.00.20.40.10.20.20.1-0.10.4-0.40.2-0.4-0.60.9-0.6
Locomotion velocity, session 10.40.51.80.20.60.6-0.7-0.40.3-0.40.60.40.40.5-0.5-0.50.4-0.8-1.1-1.11.1-1.3
Locomotion distance, session 10.00.10.40.40.1-0.10.00.1-0.10.3-0.1-0.1-0.1-0.20.2-0.20.10.20.60.3-0.10.3
Locomotion velocity, session 20.50.51.20.20.90.7-0.8-0.90.7-0.60.70.70.70.5-0.6-1.10.8-0.8-1.0-0.10.4-0.8
Locomotion distance, session 20.20.21.4-0.20.40.2-0.2-0.20.20.40.20.20.20.2-0.1-0.60.6-0.10.31.2-1.00.2
Locomotion velocity, session 30.30.31.4-0.2-0.4-0.60.60.8-0.70.4-0.6-0.7-0.7-0.60.60.5-1.20.50.5-0.0-0.20.6
Locomotion distance, session 30.10.10.60.80.3-0.1-0.2-0.30.3-0.30.30.30.30.4-0.4-0.2-0.5-0.00.3-0.0-0.40.5
Stereotopy head waving bouts, day 31.31.53.1-0.8-1.0-0.91.31.2-1.01.1-1.2-1.3-1.3-1.21.21.5-1.81.51.21.0-1.31.4
Stereotopy head waving duration, day 31.11.31.9-0.9-1.0-0.81.21.0-0.90.8-1.2-1.3-1.3-1.31.31.2-1.11.41.11.1-1.21.3
Locomotion velocity, session 70.60.62.50.0-0.3-0.30.70.8-0.41.6-0.5-0.5-0.5-0.60.71.4-0.11.10.71.0-1.2-0.0
Locomotion distance, session 70.20.30.90.90.60.4-0.4-0.30.60.30.50.50.50.6-0.50.40.4-0.1-0.3-0.50.4-1.0
Stereotopy head waving bouts, day 70.10.20.8-0.00.20.4-0.2-0.40.5-0.10.40.40.40.4-0.30.2-0.5-0.1-0.9-0.2-0.1-0.6
Stereotopy head waving duration, day 70.10.10.4-0.5-0.3-0.10.30.2-0.10.3-0.2-0.1-0.1-0.20.20.4-0.70.2-0.30.2-0.3-0.0
Locomotion velocity, session 80.81.01.60.51.01.0-1.0-0.91.0-0.21.21.11.11.1-1.1-1.21.1-1.0-1.3-0.00.8-1.2
Locomotion distance, session 80.10.10.40.40.10.3-0.1-0.10.30.70.30.40.40.3-0.3-0.20.3-0.0-0.20.6-0.1-0.4
Degree of sensitization distance0.10.10.6-0.1-0.20.00.30.4-0.20.7-0.2-0.3-0.3-0.20.30.80.30.4-0.0-0.20.5-0.6
Degree of sensitization stereotypy0.30.31.10.10.40.5-0.5-0.50.6-0.00.60.70.70.6-0.60.1-0.4-0.4-1.1-0.60.4-1.1
Conditioned locomotion1.11.33.0-0.5-1.3-1.01.21.2-0.91.2-1.1-1.1-1.1-1.01.11.7-1.41.31.50.5-1.20.8
Cocaine response after cond. corrected0.20.21.1-0.7-0.3-0.30.20.10.10.9-0.00.00.00.1-0.00.50.10.1-0.6-0.10.3-1.0
Cocaine response after cond. not corrected0.20.21.2-0.4-0.4-0.40.30.3-0.10.9-0.1-0.1-0.10.00.00.6-0.20.1-0.5-0.50.8-1.1
Cocaine response before conditioning0.81.02.31.50.91.0-1.0-0.80.7-1.20.90.80.80.9-0.9-1.00.4-1.1-0.8-1.31.4-0.7
Saline control response0.30.42.01.40.40.3-0.3-0.50.4-0.90.30.40.40.5-0.5-0.90.6-0.60.9-0.1-0.30.7
Bone: connectivity density0.61.02.0-0.4-1.0-0.81.01.0-0.91.2-1.1-1.1-1.1-1.21.11.4-1.11.11.40.1-0.10.8
Bone: cortical apparent density0.20.31.40.1-0.10.1-0.0-0.20.30.20.00.10.10.00.1-0.0-0.30.50.71.2-1.20.9
Bone: cortical area0.20.30.90.60.50.8-0.6-0.50.4-0.50.50.60.60.6-0.6-0.51.0-0.70.3-0.40.8-0.1
Bone: cortical porosity5.56.08.3-2.6-2.4-2.62.52.6-2.62.7-2.6-2.5-2.5-2.62.52.6-1.32.52.92.2-1.82.1
Bone: cortical porosity3.94.36.3-2.0-2.0-2.22.12.1-2.12.4-2.2-2.1-2.1-2.12.02.3-1.32.32.51.9-1.61.7
Bone: cortical thickness1.22.04.02.01.51.7-1.5-1.51.4-1.11.41.51.51.4-1.5-1.41.4-1.4-0.3-1.11.5-0.9
Bone: cortical thickness0.60.74.12.00.20.4-0.20.00.10.50.20.40.40.3-0.30.6-0.60.00.7-1.82.0-0.9
Bone: cortical tissue density0.30.31.8-0.0-0.2-0.10.1-0.00.10.4-0.1-0.1-0.1-0.10.20.1-0.50.70.81.3-1.41.1
Condit. Reinf. active minus inactive responses0.20.31.9-0.4-0.4-0.50.30.3-0.21.4-0.3-0.3-0.3-0.30.20.8-0.40.60.30.1-0.2-0.8
Condit. Reinf. active-inactive response ratio0.30.31.00.50.40.7-0.5-0.60.60.50.50.60.60.5-0.6-0.30.7-0.2-0.20.1-0.2-1.0
Condit. Reinf. active responses0.40.52.7-0.7-0.8-0.80.50.6-0.41.6-0.5-0.4-0.4-0.40.41.2-0.70.70.10.1-0.3-0.9
Condit. Reinf. inactive responses0.70.82.1-0.8-1.1-1.30.91.0-0.81.2-0.8-0.8-0.8-0.70.71.3-1.50.80.50.0-0.30.0
Incentive salience index mean0.60.72.7-0.9-0.8-0.80.60.7-0.71.6-0.7-0.6-0.6-0.60.61.1-0.31.00.71.1-1.1-0.1
Condit. Reinf. lever presses0.20.21.5-0.20.2-0.0-0.3-0.10.20.30.20.20.20.4-0.20.21.00.1-0.41.2-1.1-0.4
Condit. Reinf. active minus inactive responses2.22.74.61.82.12.1-2.0-1.71.6-1.31.71.71.71.7-1.7-1.61.5-1.5-1.5-0.90.9-1.7
Condit. Reinf. active-inactive response ratio1.51.63.41.21.51.8-1.5-1.31.2-1.31.31.31.31.4-1.3-1.11.3-1.1-1.0-0.50.6-0.7
Condit. Reinf. active responses3.24.46.22.42.52.4-2.4-2.11.9-1.92.22.02.02.0-2.0-2.41.8-2.1-2.2-1.41.1-2.3
Condit. Reinf. inactive responses1.82.23.71.61.61.3-1.6-1.41.3-1.31.61.41.41.3-1.4-1.71.3-1.7-1.8-1.30.9-1.9
Condit. Reinf. lever presses3.95.311.23.43.02.6-2.7-2.42.1-2.12.42.32.32.3-2.3-2.41.9-2.1-1.8-1.81.2-2.2
Condit. Reinf. lever reinforcers received3.75.27.92.72.82.7-2.6-2.32.1-2.02.42.32.32.3-2.2-2.42.0-2.2-2.3-1.61.3-2.5
Conditioned reinforcement - actives1.91.94.2-2.1-1.5-1.51.41.4-1.31.5-1.4-1.5-1.5-1.61.51.3-0.81.01.11.3-0.80.9
Conditioned reinforcement - inactives0.40.53.5-0.6-0.5-0.10.2-0.00.30.7-0.1-0.2-0.2-0.20.20.30.20.21.01.9-1.40.8
Conditioned locomotion0.91.13.8-2.0-1.2-1.00.80.8-0.90.7-1.0-1.1-1.1-1.21.10.7-0.40.41.01.3-0.91.0
Patch foraging indifference point 0 sec0.20.31.00.40.0-0.50.20.1-0.10.3-0.2-0.3-0.3-0.20.20.2-0.80.51.00.7-1.00.8
Patch foraging indifference point AUC0.30.41.7-0.8-0.4-0.30.40.7-0.71.3-0.4-0.3-0.3-0.40.40.3-0.90.70.30.9-0.90.1
Delay disc. indifference point, 0s delay0.00.00.20.2-0.20.1-0.0-0.20.3-0.20.10.10.10.2-0.10.3-0.20.0-0.00.1-0.40.1
Delay disc. indifference point, 16s delay0.10.10.70.90.00.1-0.0-0.00.20.10.1-0.0-0.0-0.00.10.4-0.20.30.3-0.0-0.50.2
Delay disc. indifference point, 2s delay1.11.22.4-0.7-1.5-1.21.11.0-0.91.5-1.0-0.7-0.7-0.80.81.2-1.31.11.41.2-1.10.7
Delay disc. indifference point, 24s delay0.40.42.81.71.00.4-0.7-0.50.60.30.70.60.60.5-0.5-0.60.20.1-0.20.2-0.5-0.5
Delay disc. indifference point, 4s delay0.10.10.50.4-0.4-0.30.10.2-0.10.1-0.10.00.0-0.10.10.6-0.6-0.10.1-0.70.5-0.4
Delay disc. indifference point, 8s delay0.20.21.70.8-0.0-0.4-0.0-0.10.1-0.3-0.1-0.2-0.2-0.20.3-0.1-0.40.1-0.4-1.31.1-0.4
Indifference point function ln k0.20.31.20.90.40.3-0.4-0.70.6-1.10.30.10.10.2-0.3-0.50.7-0.50.1-0.20.20.2
Indifference point function log k0.20.31.20.90.40.3-0.4-0.70.6-1.10.30.10.10.2-0.3-0.50.7-0.50.1-0.20.20.2
Patch foraging total patch changes 0 sec0.10.20.70.3-0.0-0.50.20.1-0.10.2-0.2-0.3-0.3-0.20.20.3-0.80.50.80.5-0.90.7
Patch foraging total patch changes 12 sec0.20.30.7-0.7-0.1-0.40.30.4-0.50.6-0.4-0.3-0.3-0.40.40.2-0.80.60.70.8-0.70.8
Patch foraging total patch changes 18 sec0.10.21.2-0.00.00.1-0.1-0.20.30.70.20.30.30.3-0.30.2-0.10.20.50.7-1.10.0
Patch foraging total patch changes 24 sec2.02.55.3-1.9-1.4-1.41.31.2-1.31.5-1.4-1.2-1.2-1.31.30.9-1.41.42.12.3-2.02.3
Patch foraging total patch changes 6 sec0.10.21.1-0.30.30.2-0.3-0.30.2-0.20.30.40.40.3-0.3-0.5-0.0-0.20.00.7-1.10.4
Patch foraging time to switch 0 sec0.10.21.4-0.4-0.2-0.40.20.3-0.10.3-0.2-0.2-0.2-0.30.30.8-0.20.2-0.3-0.91.2-0.5
Patch foraging water rate 0 sec0.91.52.30.81.31.5-1.2-1.41.2-1.21.31.41.41.4-1.4-1.51.4-1.1-0.90.6-1.0-0.3
Patch foraging water rate 12 sec0.50.81.80.50.71.3-0.8-1.21.1-0.50.90.90.90.9-1.0-1.41.1-0.9-0.40.7-0.6-0.2
Patch foraging water rate 18 sec0.10.20.9-0.9-0.30.4-0.1-0.30.3-0.20.20.30.30.3-0.4-0.50.5-0.6-0.40.50.1-0.1
Patch foraging water rate 24 sec0.20.31.00.70.20.8-0.4-0.81.00.10.50.60.60.7-0.6-0.30.10.0-0.00.4-0.4-0.1
Patch foraging water rate 6 sec0.20.31.00.10.10.6-0.4-0.80.7-0.70.50.30.30.4-0.5-1.01.0-0.9-0.6-0.00.1-0.3
Seeking ratio, delayed vs. immediate footshock2.63.05.80.82.02.1-1.8-1.81.9-2.11.92.22.22.2-2.1-1.32.4-1.5-1.3-0.10.2-0.6
Distance traveled before self-admin2.12.24.9-1.4-2.2-1.91.61.4-1.60.3-1.7-1.9-1.9-1.81.61.1-0.90.20.7-1.31.70.6
Distance traveled after self-admin2.22.44.7-0.6-2.2-1.91.81.8-1.71.3-1.6-1.6-1.6-1.61.51.7-2.11.10.5-1.51.4-0.0
Extensor digitorum longus weight0.20.72.0-0.9-1.3-0.80.90.9-0.9-0.6-0.8-0.7-0.7-0.70.70.5-0.90.00.7-0.60.71.4
Bone: elastic displacement0.91.03.41.10.70.7-1.0-1.00.7-1.50.80.80.80.6-0.8-1.40.6-1.3-0.3-1.81.5-0.6
Bone: elastic work0.40.51.20.70.40.4-0.8-0.70.5-0.70.50.70.70.6-0.8-0.90.6-1.00.6-1.10.7-0.3
Bone: endosteal estimation2.04.46.6-2.5-2.4-2.62.32.3-2.42.0-2.2-2.2-2.2-2.12.12.2-1.82.01.81.4-1.61.7
Bone: endosteal perimeter0.40.81.8-1.3-1.2-0.91.01.2-1.30.2-1.0-1.0-1.0-0.90.90.9-0.30.20.5-0.40.60.6
Epididymis fat weight1.73.97.1-2.3-2.0-1.82.01.8-1.72.7-1.9-1.9-1.9-2.02.01.4-1.12.01.92.3-2.71.5
Delta time in closed arm before/after self-admin1.01.02.3-0.2-0.6-0.80.80.7-0.71.5-0.7-0.7-0.7-0.90.90.6-1.41.51.11.5-1.21.0
Delta time in open arm before/after self-admin0.70.63.01.70.20.9-0.5-0.71.1-0.20.80.80.80.9-0.8-0.40.1-0.5-0.7-1.00.5-1.2
Diff in mean of infusions in LGA sessions0.20.20.80.50.30.3-0.2-0.40.3-0.80.30.20.20.3-0.3-0.7-0.5-0.2-0.4-0.70.90.3
Delay discount exponential model param0.10.11.7-1.30.10.20.00.0-0.2-0.2-0.1-0.0-0.0-0.0-0.1-0.00.5-0.20.00.6-0.30.4
Extinction: sum of active levers before priming1.31.22.51.21.61.4-1.3-1.21.2-1.21.21.41.41.4-1.2-1.10.6-0.4-0.40.6-0.40.3
Active lever presses in extinction session 60.30.31.40.40.60.6-0.6-0.50.4-1.20.40.20.20.4-0.3-0.70.1-0.7-0.1-0.40.80.3
Bone: final force0.81.44.9-0.5-1.3-1.11.11.1-1.11.4-1.2-1.0-1.0-1.01.01.2-0.81.02.20.6-1.21.0
Bone: final moment0.71.24.9-0.4-1.2-1.01.01.0-1.11.3-1.1-1.0-1.0-1.01.01.0-0.81.02.20.6-1.21.1
Food consumed during 24 hour testing period6.78.119.24.43.42.7-3.1-3.13.1-2.93.03.03.03.0-2.9-3.02.4-2.5-2.0-2.01.7-1.8
Glucose1.72.58.61.91.31.2-1.2-1.11.1-1.51.21.11.11.2-1.2-0.91.2-1.6-1.8-2.92.6-2.2
Heart weight0.30.40.8-0.5-0.9-0.70.70.8-0.80.9-0.7-0.6-0.6-0.60.60.9-0.90.60.2-0.2-0.1-0.1
Delay discount hyperbolic model param0.10.11.0-1.00.30.4-0.2-0.20.1-0.40.10.10.10.2-0.2-0.30.6-0.3-0.20.5-0.30.4
Intermittent access intake day 1-15 change1.61.52.6-1.4-1.4-1.41.31.4-1.60.4-1.4-1.4-1.4-1.41.21.1-0.70.71.50.5-1.01.3
Intermittent access intake escalation1.01.01.8-1.2-1.2-1.11.01.2-1.30.4-1.1-1.1-1.1-1.11.00.9-0.60.41.10.4-0.80.9
Intermittent access intake escalation 20.80.81.2-0.9-1.0-1.01.01.1-1.11.0-0.9-1.0-1.0-0.90.90.9-0.80.50.90.6-0.80.5
Intermitt. access day 1 inactive lever presses1.11.24.9-1.1-0.9-0.70.80.6-0.51.1-0.8-0.7-0.7-0.70.70.9-1.41.01.31.9-2.21.4
Intermitt. access day 15 inactive lever presses1.41.52.7-1.5-1.4-1.21.31.2-1.21.6-1.3-1.3-1.3-1.31.31.5-1.21.30.80.9-0.60.4
Intermitt. access escalation Index4.03.67.3-0.8-1.8-2.02.02.3-2.21.4-2.2-2.1-2.1-2.12.22.3-2.72.01.3-0.80.11.0
Intermittent access day 1 total infusions0.30.31.9-0.3-0.4-0.30.30.3-0.20.6-0.3-0.4-0.4-0.40.40.30.10.41.11.4-1.00.7
Intermittent access day 15 total infusions0.50.51.1-0.9-0.8-0.60.60.8-0.80.3-0.7-0.6-0.6-0.60.60.5-0.20.21.10.9-1.00.8
Intermittent access terminal intake (last 3 days)1.41.62.6-0.9-1.3-1.41.21.5-1.61.1-1.4-1.4-1.4-1.41.31.1-1.00.91.61.0-1.21.1
Intermittent access total infusions0.20.30.9-0.7-0.6-0.40.40.5-0.60.4-0.4-0.4-0.4-0.40.30.3-0.50.20.70.9-0.70.6
Intermittent access day 1 locomotion0.30.31.4-0.3-0.4-0.20.30.2-0.20.4-0.3-0.3-0.3-0.40.30.40.20.40.91.2-0.90.7
Intermittent access day 15 total locomotion0.50.61.3-0.8-0.9-0.60.70.7-0.80.5-0.7-0.7-0.7-0.80.70.10.10.41.11.1-0.70.9
Intermittent access total locomotion0.91.02.0-0.8-1.3-1.01.10.9-1.10.5-1.1-1.1-1.1-1.11.00.4-0.50.61.41.0-0.91.2
Intermittent access standard deviation0.70.71.6-0.7-1.3-0.90.91.0-1.00.5-1.0-0.9-0.9-0.90.80.7-0.60.31.20.5-0.70.8
Left kidney weight2.15.88.2-1.3-2.5-2.52.62.6-2.52.3-2.7-2.5-2.5-2.62.72.9-2.62.72.61.2-1.62.0
Right kidney weight1.64.66.8-1.3-2.2-2.32.42.5-2.32.2-2.4-2.3-2.3-2.42.42.6-2.12.61.81.1-1.31.3
Cocaine induced anxiety0.20.30.50.20.70.7-0.5-0.60.70.00.70.70.70.7-0.6-0.20.5-0.2-0.60.4-0.1-0.5
Post-drug Anxiety0.40.42.6-0.4-0.0-0.10.40.3-0.21.6-0.1-0.2-0.2-0.20.40.4-0.51.10.41.6-0.70.2
Baseline Anxiety0.40.41.0-0.3-0.6-0.60.70.7-0.71.0-0.7-0.7-0.7-0.70.80.3-0.70.70.40.20.10.1
Tail length2.78.213.0-1.2-3.4-3.13.33.3-3.33.0-3.2-3.1-3.1-3.13.12.7-3.62.83.10.6-1.01.9
Length with tail5.319.432.1-3.2-5.0-4.74.84.8-4.75.7-4.5-4.6-4.6-4.64.64.2-5.04.74.42.7-2.82.8
Length without tail2.96.412.6-2.9-2.5-2.52.62.5-2.53.6-2.3-2.4-2.4-2.42.51.9-2.22.82.03.0-2.71.9
Times rat made contact with spout1.31.56.62.61.61.2-1.4-1.31.6-0.51.41.51.51.4-1.3-0.70.4-0.3-0.40.1-0.6-0.5
Lifetime Intake0.20.21.4-0.6-0.4-0.20.20.3-0.40.4-0.2-0.2-0.2-0.30.20.2-0.30.10.71.2-0.90.5
Liver weight, left0.91.43.1-0.8-0.7-0.71.11.0-0.81.3-1.1-1.0-1.0-1.11.21.3-1.61.81.01.2-1.61.4
Liver weight, right0.10.21.4-0.40.30.2-0.1-0.10.1-0.7-0.00.10.1-0.00.00.30.4-0.10.40.7-1.21.1
Locomotor activity1.72.73.7-1.7-1.7-1.71.71.8-1.91.4-1.8-1.7-1.7-1.81.81.6-1.81.41.70.9-1.01.5
Locomotor testing distance0.91.63.4-1.9-1.1-1.01.11.2-1.31.0-1.4-1.2-1.2-1.21.21.6-1.00.91.71.1-1.11.2
Locomotor testing rearing0.10.21.5-0.1-0.10.1-0.00.20.01.0-0.00.00.00.0-0.01.2-0.20.40.30.1-0.1-0.8
Locomotion in novel chamber0.60.72.71.60.90.6-0.7-0.70.6-1.50.50.40.40.4-0.5-0.80.6-0.6-0.4-1.41.1-0.2
Locomotion in novel chamber post-restriction0.70.92.0-0.5-0.4-0.80.70.7-0.61.2-0.7-0.7-0.7-0.70.80.9-1.21.31.41.4-0.91.1
Fecal boli incidents, locomotor time 10.30.40.90.7-0.2-0.30.50.6-0.51.0-0.5-0.7-0.7-0.60.70.6-0.50.50.9-0.6-0.1-0.0
Change in fecal boli incidents, locomotor task0.30.31.40.1-0.7-0.70.50.5-0.50.2-0.4-0.4-0.4-0.50.40.3-1.20.50.2-0.0-0.60.3
Time >=10cm from walls, locomotor time 11.01.01.9-1.3-1.3-1.31.11.0-1.20.5-1.1-1.4-1.4-1.21.10.6-1.20.20.7-0.4-0.40.7
Bouts of movement, locomotor time 15.56.010.41.92.22.5-2.5-2.52.3-2.22.52.42.42.3-2.5-2.72.6-3.2-2.4-2.22.8-2.3
Total resting periods, locomotor time 13.84.27.51.51.72.2-2.1-2.02.0-1.82.12.12.11.9-2.1-2.22.2-2.7-1.9-1.72.3-1.9
Rest time, locomotor task time 10.40.51.2-0.40.61.1-0.8-0.80.8-0.40.70.70.70.6-0.6-0.90.7-0.8-0.10.9-0.50.4
Distance moved, locomotor task time 12.42.64.3-0.7-1.8-2.11.92.0-1.91.6-1.8-1.7-1.7-1.71.71.6-1.71.81.40.3-0.90.8
Vertical activity count, locomotor time 11.71.83.0-0.7-1.7-1.71.61.7-1.61.2-1.5-1.5-1.5-1.61.51.3-1.51.30.4-0.6-0.00.0
Time >=10cm from walls, locomotor time 22.52.64.3-1.0-1.8-1.81.81.7-1.71.2-1.9-2.1-2.1-1.92.01.7-2.01.41.3-0.50.51.0
Bouts of movement, locomotor time 20.30.31.5-1.10.1-0.2-0.3-0.2-0.0-0.50.10.10.10.0-0.1-0.40.9-0.8-0.5-0.41.2-0.4
Total resting periods, locomotor time 20.40.41.7-1.10.20.1-0.5-0.40.2-0.60.30.30.30.2-0.2-0.51.2-1.0-0.7-0.21.3-0.6
Rest time, locomotor task time 22.02.35.40.21.41.6-1.6-1.61.5-1.51.71.51.51.4-1.5-2.02.3-2.1-1.7-0.10.6-1.0
Distance moved, locomotor task time 22.12.45.5-0.8-1.6-1.61.71.7-1.41.6-1.6-1.5-1.5-1.51.52.0-2.32.11.40.6-1.01.1
Vertical activity count, locomotor time 23.13.46.8-1.4-2.1-2.12.01.9-1.72.1-1.9-2.0-2.0-2.01.92.3-2.62.11.40.0-0.40.8
Light reinforcement 10.00.10.8-0.1-0.10.1-0.10.1-0.10.6-0.0-0.1-0.1-0.10.00.10.2-0.20.0-0.0-0.2-0.9
Light reinforcement 20.60.82.00.20.80.9-0.9-0.91.10.20.91.11.11.1-0.9-0.60.9-0.4-0.81.2-1.4-0.8
Bone: marrow area2.14.66.8-2.6-2.4-2.62.32.4-2.42.0-2.3-2.2-2.2-2.12.22.3-1.82.01.91.5-1.71.8
Bone: maximum diameter0.71.23.90.20.51.0-0.8-0.70.6-1.50.80.90.90.9-1.0-0.81.7-1.5-1.2-1.42.0-0.9
Bone: maximum force0.20.41.6-0.3-0.7-0.70.60.6-0.60.7-0.7-0.5-0.5-0.50.50.6-0.20.61.30.6-0.90.8
Bone: maximum moment0.20.31.4-0.1-0.5-0.50.50.4-0.50.6-0.5-0.4-0.4-0.40.40.3-0.20.51.20.5-0.80.7
Mean time between licks in bursts0.20.31.90.50.30.0-0.20.00.10.10.10.20.20.1-0.20.60.5-0.1-0.6-1.11.4-1.2
Mean num. licks in bursts0.20.32.30.60.50.2-0.2-0.10.20.10.30.30.30.4-0.3-0.1-0.60.4-0.20.8-1.50.2
Cd content in liver3.94.36.82.21.71.7-2.1-2.12.0-2.41.91.91.91.9-2.1-1.92.2-2.6-1.6-2.52.4-2.0
Co content in liver0.40.41.10.60.50.5-0.6-0.70.7-1.00.70.70.70.7-0.7-0.80.3-0.7-1.0-0.40.4-0.3
Cu content in liver1.01.22.6-1.6-1.2-1.51.11.0-1.11.0-1.0-1.2-1.2-1.11.00.8-0.70.61.20.9-0.71.0
Fe content in liver0.70.92.4-0.40.70.7-0.9-1.01.0-0.11.01.01.01.0-1.0-1.31.6-1.0-0.90.7-0.6-1.0
K content in liver7.17.012.5-3.5-2.9-3.32.92.8-3.02.1-2.8-3.0-3.0-2.92.81.9-2.02.12.31.9-1.52.6
Mg content in liver1.01.02.4-1.5-1.1-1.21.11.1-1.20.8-1.0-1.1-1.1-1.01.00.7-0.80.70.90.7-0.41.1
Mn content in liver0.91.03.1-1.2-0.7-0.60.90.8-0.80.7-0.8-0.7-0.7-0.70.80.6-0.41.01.21.8-1.71.5
Na content in liver2.02.18.4-2.5-0.8-1.31.21.1-1.21.3-1.1-1.1-1.1-1.11.20.7-0.01.50.52.9-2.41.4
Rb content in liver1.82.24.31.21.81.7-1.7-1.81.6-1.91.71.51.51.6-1.6-2.11.5-1.6-0.9-0.50.7-0.2
Se content in liver0.40.42.7-0.4-0.1-0.30.40.1-0.31.0-0.3-0.3-0.3-0.30.4-0.2-0.30.70.61.6-1.60.5
Sr content in liver0.30.30.90.2-0.7-0.50.40.4-0.5-0.1-0.5-0.5-0.5-0.50.40.4-0.5-0.00.1-1.01.0-0.1
Zn content in liver1.92.13.7-1.5-1.8-1.91.61.6-1.51.4-1.5-1.5-1.5-1.51.51.4-1.61.11.70.5-0.21.2
Bone: minimum diameter0.20.41.0-0.9-0.7-0.60.70.9-1.00.8-0.7-0.7-0.7-0.60.70.7-0.30.50.50.3-0.10.3
Time in familiar zone, hab. session 10.70.71.9-0.10.60.6-0.8-0.50.2-0.90.70.70.70.5-0.7-0.80.4-1.2-1.2-1.41.4-1.0
Time in novel zone, hab. session 10.50.51.30.3-0.7-0.70.80.5-0.21.2-0.7-0.8-0.8-0.70.81.0-0.61.00.90.2-0.30.2
Total zone transitions, hab. session 10.10.20.50.10.10.2-0.2-0.30.30.50.40.50.50.4-0.4-0.7-0.6-0.0-0.10.6-0.50.1
Total locomotion distance, hab. session 10.10.20.7-0.4-0.4-0.60.40.0-0.10.8-0.2-0.2-0.2-0.30.2-0.4-0.80.40.20.8-0.60.3
Locomotion velocity, hab. session 10.10.20.6-0.5-0.4-0.60.30.0-0.10.6-0.2-0.2-0.2-0.20.2-0.4-0.70.40.20.8-0.60.4
Time in familiar zone, hab. session 20.30.31.7-1.3-0.5-0.30.30.6-0.8-0.1-0.5-0.5-0.5-0.50.50.4-0.2-0.00.4-0.00.10.7
Time in novel zone, hab. session 20.10.10.80.90.1-0.1-0.1-0.40.40.10.0-0.0-0.0-0.1-0.0-0.3-0.00.0-0.1-0.70.6-0.7
Total zone transitions, hab. session 21.11.43.0-1.0-1.0-1.31.11.0-1.01.4-1.0-0.9-0.9-1.01.00.7-1.21.41.31.7-1.51.3
Total locomotion distance, hab. session 21.82.44.8-1.3-1.9-2.21.81.5-1.31.6-1.7-1.7-1.7-1.81.71.2-1.81.71.41.0-0.71.3
Locomotion velocity, hab. session 21.11.53.1-1.1-1.4-1.81.41.1-1.01.3-1.2-1.2-1.2-1.31.30.7-1.31.31.01.1-0.81.1
Novel to familiar place preference ratio0.40.51.30.50.40.2-0.5-0.70.7-0.20.70.60.60.7-0.7-0.70.2-0.6-1.0-0.90.8-1.2
Novelty place preference0.40.41.20.30.20.1-0.5-0.60.6-0.20.60.60.60.6-0.6-0.70.2-0.7-1.0-0.80.8-1.1
Time in novel zone, NPP test0.70.71.80.50.40.3-0.7-0.80.8-0.40.80.80.80.8-0.8-0.90.3-0.9-1.1-1.21.2-1.3
Total zone transitions, NPP test0.20.20.70.50.40.2-0.4-0.60.5-0.30.50.50.50.5-0.5-0.80.5-0.40.10.5-0.30.2
Total locomotion distance, NPP test0.20.20.70.20.2-0.1-0.3-0.70.8-0.60.40.40.40.3-0.4-0.80.8-0.4-0.20.5-0.10.2
Locomotion velocity, NPP test0.20.30.90.20.30.0-0.4-0.80.8-0.70.50.50.50.4-0.4-0.90.9-0.4-0.40.7-0.30.3
Intraocular pressure0.40.52.41.10.70.6-0.6-0.50.5-0.20.50.40.40.4-0.40.1-0.6-0.2-0.7-1.51.1-1.1
Delta distance traveled before/after self-admin0.30.31.51.10.20.10.20.4-0.01.00.00.30.30.2-0.10.6-1.21.2-0.10.0-0.6-0.5
Delta ambulatory time before/after self-admin0.30.42.51.60.50.3-0.10.10.20.90.30.40.40.3-0.20.3-0.81.0-0.4-0.1-0.5-0.9
Parametrial fat weight0.50.93.5-0.2-0.8-0.60.81.1-0.81.9-0.7-0.7-0.7-0.80.91.2-0.71.40.31.2-1.3-0.0
Pavlov. Cond. lever latency0.10.20.7-0.3-0.4-0.10.40.4-0.5-0.1-0.4-0.3-0.3-0.50.40.2-0.60.10.1-0.80.80.1
Pavlov. Cond. magazine entry latency0.20.31.20.80.60.4-0.3-0.30.50.20.40.50.50.6-0.40.3-0.20.60.11.1-1.00.3
Pavlov. Cond. change in total contacts0.40.52.90.1-0.1-0.20.30.3-0.30.6-0.3-0.3-0.3-0.10.20.4-0.70.90.61.6-1.70.8
Pavlov. Cond. index score0.20.21.50.40.50.2-0.4-0.40.50.20.40.40.40.6-0.40.10.20.30.01.2-1.10.1
Pavlov. Cond. latency score0.30.41.40.50.70.4-0.6-0.60.70.00.60.60.60.8-0.7-0.30.5-0.0-0.21.2-1.0-0.1
Pavlov. Cond. lever contacts0.20.22.1-0.20.1-0.1-0.1-0.10.20.50.10.10.10.3-0.2-0.00.40.20.11.4-1.30.1
Pavlov. Cond. magazine entry number0.20.31.2-1.1-0.7-0.50.50.4-0.60.2-0.5-0.6-0.6-0.70.6-0.00.3-0.20.3-0.30.30.0
Pavlov. Cond. intertrial magazine entries1.51.84.9-1.6-1.1-0.91.01.0-1.01.3-1.1-0.8-0.8-0.90.91.0-0.91.41.92.2-2.21.8
Pavlov. Cond. lever-magazine prob. diff.0.20.32.00.30.40.1-0.2-0.20.30.30.20.30.30.4-0.30.10.10.40.11.4-1.20.3
Pavlov. Cond. response bias0.20.20.80.70.50.2-0.3-0.30.50.10.30.40.40.5-0.40.1-0.00.4-0.10.9-0.80.1
Pavlov. Cond. lever latency4.15.511.2-3.4-2.7-2.52.62.3-2.22.1-2.4-2.3-2.3-2.32.32.3-2.02.31.72.1-1.82.3
Pavlov. Cond. magazine entry latency3.43.911.63.42.42.2-2.1-2.12.2-0.62.12.12.12.0-2.0-1.61.3-1.1-1.7-1.31.4-2.4
Pavlov. Cond. change in total contacts5.98.111.33.33.43.2-3.2-2.82.8-2.13.02.82.82.8-2.8-2.52.8-2.7-2.6-2.32.4-3.2
Pavlov. Cond. index score5.57.014.73.83.12.9-2.9-2.72.7-1.92.82.72.72.7-2.7-2.32.3-2.3-2.0-2.22.1-2.8
Pavlov. Cond. latency score5.46.713.93.73.12.9-2.9-2.72.7-1.82.72.72.72.7-2.6-2.22.2-2.2-2.0-2.12.0-2.7
Pavlov. Cond. lever contacts2.63.58.52.92.11.9-2.0-1.81.7-1.71.81.71.71.7-1.8-1.71.6-1.8-1.3-2.11.6-1.9
Pavlov. Cond. magazine entry number6.27.613.0-3.6-3.3-3.03.13.0-3.01.9-3.0-2.9-2.9-2.92.92.9-2.62.42.21.6-1.72.6
Pavlov. Cond. intertrial magazine entries0.20.20.7-0.80.20.4-0.5-0.50.3-0.70.40.50.50.5-0.5-0.70.6-0.8-0.20.1-0.10.0
Pavlov. Cond. lever-magazine prob. diff.5.16.413.43.73.02.8-2.8-2.62.6-1.82.62.62.62.6-2.5-2.32.3-2.2-1.9-2.12.0-2.6
Pavlov. Cond. response bias4.25.712.93.62.72.4-2.5-2.32.3-1.92.32.32.32.2-2.3-2.22.0-2.2-1.9-2.42.2-2.6
Time in closed arm before self-admin1.61.83.0-0.9-1.7-1.61.61.7-1.70.9-1.6-1.5-1.5-1.41.51.5-1.31.11.1-0.70.50.7
Time in closed arm after self-admin3.43.56.1-1.3-1.9-1.91.81.8-1.82.5-1.8-1.7-1.7-1.91.81.5-1.82.22.21.9-1.91.5
Time in open arm before self-admin0.70.82.20.41.31.0-1.2-1.00.8-1.50.90.80.80.8-0.8-1.10.6-1.0-0.6-0.1-0.00.0
Time in open arm after self-admin0.70.83.21.80.60.8-0.7-0.80.9-1.30.70.60.60.7-0.7-0.5-0.1-0.6-0.7-1.50.8-0.4
Bone: periosteal estimation0.51.01.6-1.2-1.3-1.21.11.2-1.20.9-1.1-1.0-1.0-1.01.01.1-0.50.81.10.5-0.40.8
Bone: periosteal perimeter0.10.21.9-0.5-0.30.10.00.4-0.5-0.2-0.1-0.0-0.0-0.0-0.10.00.4-0.70.0-1.01.4-0.3
Bone: post-yield work0.40.61.2-1.0-0.8-0.60.80.8-0.81.0-0.8-0.6-0.6-0.60.70.8-0.61.1-0.21.0-1.00.2
Progressive ratio test 1 active lever presses0.20.31.00.20.40.5-0.4-0.30.2-0.90.30.40.40.4-0.4-0.60.4-0.40.10.8-1.00.6
Progressive ratio test 1 breakpoint0.20.30.90.10.30.4-0.4-0.40.2-0.90.20.30.30.3-0.3-0.70.4-0.50.20.8-0.90.7
Progressive ratio test 1 inactive lever presses0.90.94.4-0.9-0.6-0.50.60.4-0.41.0-0.6-0.6-0.6-0.60.60.7-0.70.91.02.1-2.11.1
Progressive ratio test 2 active lever presses1.92.03.2-1.4-1.6-1.31.41.5-1.51.3-1.4-1.3-1.3-1.41.41.1-1.41.11.61.7-1.81.5
Progressive ratio test 2 breakpoint1.82.02.8-1.3-1.7-1.31.41.5-1.51.3-1.4-1.4-1.4-1.41.41.2-1.41.11.61.5-1.71.4
Progressive ratio test 2 inactive lever presses0.60.75.2-1.2-0.10.3-0.0-0.10.10.40.10.10.10.1-0.10.10.30.00.42.3-2.20.7
Incentive Sensitization - Responses3.94.06.1-1.6-2.5-2.12.32.2-2.12.3-2.1-2.2-2.2-2.22.22.0-2.01.92.01.1-1.01.3
Incentive Sensitization - Breakpoint4.04.16.1-1.5-2.5-2.22.32.3-2.12.3-2.1-2.2-2.2-2.22.22.0-2.11.92.11.1-1.01.4
Sum of active levers in priming session hrs 5-61.71.65.72.41.81.6-1.4-1.31.4-1.11.31.21.21.3-1.1-1.1-0.0-0.4-1.2-0.90.8-0.7
Progressive ratio0.20.21.1-0.20.20.1-0.1-0.30.1-1.10.0-0.1-0.1-0.1-0.1-0.50.9-0.40.40.4-0.30.8
Food seeking constrained by brief footshock2.53.04.5-0.01.52.0-1.8-2.02.1-1.81.91.91.92.0-2.0-1.82.0-1.9-2.1-0.40.9-1.1
Seeking ratio, punishment vs. effort0.50.61.2-0.10.50.9-0.8-0.81.0-0.20.91.01.01.0-0.9-0.40.6-0.7-1.1-0.30.6-0.8
Retroperitoneal fat weight3.210.514.9-3.8-3.3-3.53.43.3-3.23.9-3.4-3.5-3.5-3.53.63.0-3.03.62.62.5-2.42.4
Reaction time number correct0.30.51.61.1-0.9-0.30.50.3-0.10.7-0.3-0.0-0.0-0.20.11.3-0.90.60.7-1.10.9-0.5
Reaction time mean minus median0.10.11.2-0.10.6-0.0-0.2-0.2-0.2-0.2-0.0-0.1-0.1-0.20.2-1.10.10.0-0.4-0.10.5-0.0
Reaction time mean minus median AUC0.20.20.60.00.1-0.50.30.3-0.60.3-0.5-0.6-0.6-0.80.7-0.5-0.30.60.3-0.10.50.3
Reaction time num false alarms15.420.926.5-4.0-4.7-5.14.75.1-5.25.0-4.9-4.9-4.9-4.94.84.8-4.44.75.02.8-2.53.3
Reaction time num false alarms AUC14.319.725.4-3.9-4.6-5.04.64.9-5.04.6-4.8-4.9-4.9-4.84.84.5-4.14.54.72.6-2.43.2
Reaction time trials correct on left0.30.51.61.1-0.9-0.30.50.3-0.10.7-0.3-0.0-0.0-0.20.11.3-0.90.60.7-1.10.9-0.5
Reaction time trials on left0.30.51.51.1-0.8-0.30.50.3-0.10.7-0.4-0.0-0.0-0.20.11.2-1.00.60.7-1.10.9-0.5
Reaction time mean0.60.82.70.90.90.3-0.8-0.70.6-0.30.70.70.70.6-0.7-1.00.2-0.8-1.0-1.51.6-1.3
Reaction time mean AUC0.40.61.90.90.80.3-0.6-0.50.5-0.20.60.50.50.5-0.5-1.00.1-0.5-0.9-1.31.4-1.1
Median of all reaction times1.01.34.41.20.90.6-1.0-0.90.9-0.61.00.90.91.0-1.0-0.90.3-1.1-1.3-2.12.1-1.7
Reaction time omissions0.10.10.60.30.3-0.10.10.2-0.30.0-0.3-0.4-0.4-0.30.3-0.3-0.80.5-0.1-0.30.40.1
Reaction time false alarm rate9.513.218.4-3.8-3.4-4.13.74.0-4.33.6-3.9-4.1-4.1-4.04.03.2-3.13.53.72.6-2.33.0
Reaction time premature initiation rate1.72.37.3-1.7-1.3-1.31.31.3-1.31.7-1.2-1.3-1.3-1.21.21.1-2.01.31.12.2-2.71.3
Reaction time premature initiations1.82.55.7-1.0-1.7-1.51.61.5-1.32.0-1.4-1.3-1.3-1.31.31.7-2.41.61.61.6-2.21.1
Std. dev. reaction times0.30.41.1-0.1-0.2-1.10.50.5-0.70.9-0.6-0.7-0.7-0.90.8-0.1-0.90.80.2-0.20.3-0.0
Reaction time trials completed0.30.51.51.1-0.8-0.30.50.3-0.10.7-0.4-0.0-0.0-0.20.11.2-1.00.60.7-1.10.9-0.5
Reaction time trials AUC0.30.51.71.2-0.7-0.20.40.20.10.7-0.20.10.1-0.00.01.3-0.90.50.6-1.31.0-0.7
Run reversals in cocaine runway, females0.70.71.6-1.1-0.5-0.80.70.8-0.81.3-0.8-0.9-0.9-0.90.91.2-0.31.00.50.00.1-0.2
Run reversals in cocaine runway, males0.20.21.0-1.0-0.5-0.30.20.3-0.10.6-0.10.00.00.0-0.00.50.3-0.30.60.8-0.30.1
Latency to leave start box in cocaine runway0.20.20.8-0.8-0.1-0.20.30.2-0.10.7-0.1-0.2-0.2-0.20.20.1-0.20.40.20.9-0.80.2
Latency to leave start box in cocaine runway, F0.10.11.2-0.30.20.10.10.10.01.10.10.10.10.1-0.0-0.0-0.20.50.10.9-0.4-0.1
Latency to leave start box in cocaine runway, M0.20.21.0-0.90.0-0.0-0.1-0.30.3-0.60.1-0.1-0.1-0.10.0-0.50.5-0.4-1.0-0.30.0-0.4
Std. dev. time between licks in bursts1.01.23.71.00.70.7-0.9-0.80.8-1.10.80.90.90.9-0.9-0.51.0-1.3-1.2-1.91.7-1.5
Total sessions with >9 infusions0.60.73.30.20.60.8-0.7-0.70.7-0.30.60.80.80.7-0.7-0.40.5-0.20.51.8-1.70.8
Short access day 1 total inactive lever presses0.40.43.30.2-0.20.10.20.20.01.00.00.00.00.00.10.5-0.60.60.31.4-1.80.2
Short access day 10 total inactive lever presses1.41.63.3-1.2-1.4-1.21.41.2-1.01.8-1.2-1.2-1.2-1.11.21.3-1.71.50.80.9-1.30.6
Short access day 1 total infusions0.50.52.1-0.6-0.4-0.30.50.6-0.60.9-0.5-0.5-0.5-0.50.60.4-0.30.70.81.5-1.20.7
Short access day 10 total infusions0.30.31.00.10.60.6-0.6-0.60.7-0.40.60.60.60.6-0.6-0.31.0-0.5-0.60.20.2-0.7
Short access total infusions0.20.21.1-0.5-0.3-0.20.20.3-0.30.5-0.3-0.3-0.3-0.30.30.10.10.20.61.1-0.80.3
Short access day 1 locomotion0.40.40.90.10.60.7-0.7-0.70.7-0.80.60.70.70.7-0.7-0.60.9-0.8-0.60.1-0.2-0.3
Short access day 10 total locomotion0.10.10.4-0.0-0.0-0.1-0.0-0.20.1-0.5-0.1-0.1-0.1-0.1-0.0-0.20.6-0.20.40.5-0.20.5
Short access total locomotion0.30.32.3-0.50.20.2-0.3-0.40.2-0.30.10.20.20.1-0.1-0.40.5-0.10.61.5-1.10.9
One hour access (0.3 mA shock)0.30.31.5-0.7-0.6-0.20.20.0-0.1-0.1-0.1-0.1-0.1-0.10.0-0.4-0.1-0.40.71.2-1.11.1
Compulsive drug intake0.80.81.41.20.90.9-0.8-0.91.2-0.51.01.01.01.0-0.8-0.50.6-0.6-1.0-1.01.1-0.7
One hour access (shock baseline)0.50.63.2-1.5-0.7-0.40.30.3-0.50.3-0.3-0.3-0.3-0.30.2-0.2-0.3-0.10.61.8-1.60.8
Social response proportion2.12.26.22.51.71.5-1.6-1.41.3-1.41.51.61.61.6-1.5-1.60.2-1.3-1.5-1.40.4-1.5
Social responses0.10.10.5-0.0-0.20.0-0.2-0.20.00.20.20.30.30.2-0.3-0.7-0.1-0.5-0.10.2-0.7-0.5
Social time0.30.41.40.2-1.2-0.80.80.7-0.70.8-0.7-0.6-0.6-0.60.60.2-0.70.40.9-0.1-0.20.3
Soleus weight2.88.211.6-3.0-3.2-3.43.03.1-3.11.7-3.1-3.2-3.2-3.23.12.6-2.82.33.30.9-1.03.4
Bone: stiffness0.20.30.7-0.1-0.8-0.70.70.7-0.60.5-0.6-0.5-0.5-0.40.50.8-0.20.40.5-0.1-0.10.3
Tibialis anterior weight0.41.53.1-1.8-1.7-1.31.41.5-1.40.1-1.4-1.3-1.3-1.41.31.1-1.00.61.0-0.0-0.01.5
Time to tail flick, vehicle, before self-admin0.10.10.2-0.1-0.30.20.10.20.00.40.00.10.10.3-0.10.5-0.30.2-0.3-0.50.2-0.5
Time to tail flick, vehicle, after self-admin4.95.28.1-0.9-2.2-2.42.52.6-2.42.6-2.5-2.4-2.4-2.42.42.8-2.72.72.40.9-1.51.4
Time to tail flick, test, before self-admin0.90.84.80.1-0.8-0.50.50.8-0.50.5-0.5-0.7-0.7-0.70.61.1-0.90.1-0.1-2.21.9-1.0
Time to tail flick, test, after self-admin1.01.04.81.20.40.6-0.7-0.70.7-1.00.60.50.50.5-0.6-0.60.5-1.0-1.3-2.21.9-1.4
Delta time to tail flick, vehicle, before/after SA3.73.75.3-0.9-1.7-2.22.12.1-2.31.9-2.2-2.2-2.2-2.32.21.7-2.02.02.20.7-0.81.5
Delta time to tail flick, test, before/after SA1.00.91.61.01.00.9-1.0-1.10.9-1.21.01.11.10.9-1.0-1.31.2-1.0-0.8-0.20.3-0.4
Tibia length0.20.64.1-0.20.0-0.10.30.3-0.30.7-0.3-0.2-0.2-0.20.30.6-0.10.81.21.7-2.01.2
Ambulatory time before self-admin1.81.85.1-1.3-2.1-1.71.41.2-1.3-0.1-1.5-1.6-1.6-1.51.40.9-0.6-0.10.5-1.62.30.5
Ambulatory time after self-admin1.21.32.90.1-1.5-1.31.31.2-1.00.8-1.1-1.0-1.0-1.11.01.3-1.40.70.2-1.71.6-0.4
Bone: tissue strength2.12.03.91.11.71.5-1.7-1.81.7-0.91.61.61.61.6-1.6-1.62.0-1.4-0.6-0.1-0.1-1.1
Total heroin consumption0.20.20.60.80.60.6-0.5-0.40.4-0.70.40.30.30.4-0.3-0.3-0.2-0.40.3-0.30.70.5
Bone: trabecular number0.10.20.8-0.0-0.1-0.10.30.2-0.30.3-0.5-0.5-0.5-0.60.40.4-0.40.50.9-0.10.30.5
Bone: trabecular spacing1.11.43.40.51.31.2-1.3-1.01.0-0.91.31.11.11.1-1.1-1.01.4-1.2-1.8-0.70.8-1.8
Bone: trabecular thickness0.10.12.11.5-0.00.20.10.00.20.0-0.00.00.00.1-0.00.4-0.10.30.3-0.30.3-0.0
Bone: trabecular tissue density0.10.10.2-0.3-0.3-0.40.20.2-0.2-0.1-0.3-0.4-0.4-0.40.4-0.1-0.30.2-0.20.00.20.4
Water consumed over 24 hours1.21.54.52.11.50.9-1.3-1.31.3-0.91.31.41.41.3-1.3-1.41.5-0.80.00.3-0.4-0.1
Number of responses in last shaping day0.00.00.2-0.10.10.2-0.00.1-0.1-0.1-0.10.10.10.1-0.10.3-0.20.20.10.1-0.50.2