Cpt1a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Cpt1a 0.02 0.01 6.2e-03 0.01 0.01 0.01 0.02 6.7e-03 5.8e-03 4.4e-03 1.6e-03
2 NAcc gene expression Cpt1a 0.07 0.05 8.7e-08 0.04 0.05 0.06 0.06 2.6e-06 2.3e-08 5.5e-09 5.8e-09
3 Adipose gene expression Cpt1a 0.06 0.04 4.5e-05 0.02 0.03 0.01 0.02 4.5e-03 7.0e-04 3.1e-02 6.1e-03
4 PL gene expression Cpt1a 0.07 0.05 4.7e-06 0.04 0.04 0.03 0.03 5.4e-05 5.2e-05 1.5e-04 3.6e-04
5 LHb gene expression Cpt1a 0.37 0.32 2.0e-03 0.12 0.08 0.11 0.02 7.9e-04 7.2e-03 1.2e-03 1.3e-01
6 OFC gene expression Cpt1a 0.28 0.15 2.3e-04 0.1 0.14 0.11 0.1 1.8e-03 4.1e-04 1.5e-03 2.2e-03
7 IC gene expression Cpt1a 0.08 0.06 7.9e-03 0.06 0.04 0.03 0.05 2.2e-03 5.7e-03 1.5e-02 4.6e-03
8 BLA gene expression Cpt1a 0.14 0.09 6.1e-05 0.08 0.06 0.07 0.07 4.7e-05 3.2e-04 1.9e-04 1.1e-04
9 pVTA gene expression Cpt1a 0.24 0.14 3.3e-15 0.18 0.19 0.2 0.19 1.6e-14 2.8e-15 4.3e-16 4.1e-15
10 Brain gene expression Cpt1a 0.22 0.09 0.0e+00 0.24 0.26 0.26 0.26 3.9e-22 9.6e-24 2.3e-24 8.1e-24
11 BLA mRNA stability Cpt1a 0.11 0.07 2.3e-05 0.07 0.04 0.05 0.05 8.7e-05 2.3e-03 1.0e-03 9.4e-04
12 PL mRNA stability Cpt1a 0.05 0.03 2.8e-05 0.04 0.04 0.04 0.04 2.2e-05 3.2e-05 7.6e-05 4.2e-05
13 Liver isoform ratio XM_017588837.2 0.13 0.08 4.4e-08 0.06 0.07 0.07 0.07 3.8e-07 3.7e-08 8.6e-08 4.4e-08
14 Liver alternative TSS NM_031559.2 0.05 0.03 1.6e-05 0.04 0.04 0.04 0.04 8.0e-06 1.1e-05 6.1e-05 1.0e-05
15 Liver alternative TSS XM_017588837.2 0.09 0.06 4.3e-07 0.06 0.06 0.06 0.06 8.4e-07 1.4e-07 8.8e-07 2.0e-07
16 Liver isoform ratio NM_031559.2 0.04 0.03 2.1e-05 0.03 0.04 0.03 0.04 1.2e-04 1.0e-05 2.9e-04 3.8e-05
17 Brain mRNA stability Cpt1a 0.06 0.04 1.1e-04 0.05 0.04 0.04 0.04 1.3e-05 2.0e-04 2.2e-04 6.6e-05
18 Liver mRNA stability Cpt1a 0.08 0.05 2.9e-07 0.06 0.06 0.05 0.05 9.4e-07 9.3e-07 3.7e-06 2.1e-06
19 IC mRNA stability Cpt1a 0.14 0.08 7.1e-05 0.07 0.09 0.07 0.07 6.6e-04 1.1e-04 5.3e-04 8.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density2.75.08.5-0.50.5-1.7-1.21.5-1.72.22.21.82.12.82.8-2.9-2.7-2.82.82.6-2.5-2.7
Area under the delay curve0.50.81.50.10.4-0.6-0.70.8-0.91.01.01.01.00.70.7-1.2-1.0-1.21.20.9-1.1-1.2
BMI with tail1.86.311.8-2.2-0.5-2.9-0.40.5-1.11.61.71.41.73.43.4-3.2-3.4-3.23.23.0-3.1-3.2
BMI without tail0.52.55.5-2.2-1.3-2.30.7-0.60.20.81.0-0.20.32.32.3-1.7-2.0-1.71.71.7-1.8-1.7
Body weight1.04.213.2-3.6-2.8-3.62.0-1.81.3-1.0-0.7-0.8-0.52.12.1-1.4-2.3-1.41.72.1-2.3-1.7
Weight adjusted by age0.20.61.5-1.2-1.2-0.81.1-1.11.0-1.0-1.2-0.8-0.9-0.2-0.20.2-0.10.2-0.2-0.3-0.10.2
Bone surface2.95.610.0-1.9-0.6-2.8-0.20.5-0.91.91.91.11.63.23.2-3.0-3.1-3.03.03.1-2.9-2.9
Bone volume2.04.17.2-0.80.2-1.7-0.91.1-1.42.12.11.31.82.62.6-2.7-2.5-2.62.52.4-2.2-2.5
Breakpoint value in progressive ratio session0.50.92.8-1.6-1.4-1.71.2-1.11.0-1.1-1.2-0.3-0.50.30.3-0.2-0.8-0.30.51.0-1.0-0.5
Number of licking bursts0.10.20.50.10.1-0.2-0.20.3-0.30.70.70.20.40.70.7-0.5-0.4-0.40.40.5-0.4-0.4
Context. condit. distance diff. score0.40.51.41.11.10.7-1.01.2-0.90.70.70.80.7-0.4-0.4-0.20.1-0.20.2-0.20.0-0.2
Locomotion velocity, session 10.10.10.70.30.3-0.1-0.20.0-0.1-0.1-0.10.30.20.90.9-0.0-0.1-0.10.10.2-0.2-0.1
Locomotion distance, session 11.52.03.6-0.20.4-1.1-0.80.6-1.11.31.31.31.51.51.5-1.9-1.7-1.81.81.8-1.6-1.8
Locomotion velocity, session 20.81.02.4-1.5-1.6-1.51.3-1.31.1-1.1-1.1-0.9-0.71.11.1-0.1-0.6-0.10.30.8-0.6-0.2
Locomotion distance, session 20.81.13.0-0.8-0.2-1.0-0.1-0.3-0.41.01.00.50.71.71.7-1.3-1.2-1.21.21.3-1.0-1.1
Locomotion velocity, session 32.02.34.80.20.8-0.8-1.11.1-1.31.41.41.51.62.22.2-1.7-1.5-1.71.71.8-1.5-1.7
Locomotion distance, session 30.20.31.00.10.2-0.2-0.30.3-0.30.40.40.40.61.01.0-0.5-0.4-0.50.50.7-0.4-0.5
Stereotopy head waving bouts, day 31.21.42.30.30.8-0.4-1.21.4-1.31.31.31.11.51.01.0-1.5-1.2-1.51.41.2-1.1-1.4
Stereotopy head waving duration, day 30.91.12.00.91.20.4-1.41.4-1.41.41.41.11.40.20.2-1.1-0.6-1.00.90.6-0.5-0.9
Locomotion velocity, session 70.70.71.4-0.10.2-0.8-0.50.8-0.60.40.41.10.70.80.8-1.0-1.2-1.11.11.1-1.2-1.1
Locomotion distance, session 70.20.20.8-0.4-0.6-0.90.4-0.20.2-0.2-0.20.0-0.10.70.7-0.4-0.7-0.40.50.4-0.7-0.5
Stereotopy head waving bouts, day 71.61.83.00.21.0-0.3-1.31.5-1.51.41.41.41.71.31.3-1.6-1.3-1.61.51.6-1.2-1.5
Stereotopy head waving duration, day 71.41.83.9-0.90.1-1.3-0.50.8-0.80.60.61.21.31.71.7-1.5-1.7-1.61.62.0-1.7-1.7
Locomotion velocity, session 80.60.82.0-1.2-1.2-1.41.1-0.80.9-1.1-1.1-0.6-0.51.11.1-0.1-0.6-0.20.40.9-0.7-0.4
Locomotion distance, session 80.50.71.70.91.00.3-1.11.0-1.11.31.31.11.00.40.4-0.9-0.4-0.80.70.4-0.3-0.7
Degree of sensitization distance0.20.20.8-0.5-0.4-0.90.20.00.1-0.1-0.10.2-0.10.30.3-0.5-0.8-0.50.60.2-0.8-0.6
Degree of sensitization stereotypy0.80.81.9-0.50.3-0.7-0.50.6-0.60.70.70.81.01.21.2-1.0-1.1-1.11.11.4-1.1-1.1
Conditioned locomotion2.32.75.4-1.5-2.0-0.62.2-2.32.2-2.1-2.2-1.9-2.1-1.0-1.01.60.91.5-1.4-0.90.81.4
Cocaine response after cond. corrected0.00.10.20.30.30.2-0.30.4-0.30.40.40.40.3-0.2-0.2-0.3-0.1-0.20.20.1-0.1-0.2
Cocaine response after cond. not corrected0.30.40.90.30.60.1-0.70.7-0.80.90.90.80.90.30.3-0.8-0.5-0.80.70.5-0.4-0.6
Cocaine response before conditioning0.30.41.0-0.20.3-0.2-0.40.3-0.51.01.00.30.71.01.0-0.8-0.5-0.70.60.6-0.4-0.6
Saline control response1.11.54.5-2.1-1.9-2.01.5-1.31.2-1.1-1.1-0.9-0.71.31.3-0.3-1.0-0.40.61.0-1.0-0.5
Bone: connectivity density3.45.510.5-1.7-0.4-2.7-0.40.7-1.01.51.51.31.73.23.2-3.0-3.1-2.93.02.9-3.0-2.9
Bone: cortical apparent density0.50.71.4-0.8-0.9-0.31.1-1.01.1-1.1-1.1-0.8-1.2-0.7-0.71.00.50.9-0.7-0.90.30.7
Bone: cortical area0.40.61.8-0.8-0.9-0.10.9-1.20.8-0.1-0.1-1.1-0.8-1.3-1.30.40.50.5-0.6-0.50.60.6
Bone: cortical porosity0.00.00.1-0.00.0-0.2-0.10.1-0.20.00.00.30.3-0.2-0.2-0.3-0.3-0.30.30.3-0.2-0.3
Bone: cortical porosity0.10.10.2-0.5-0.4-0.50.3-0.30.3-0.4-0.4-0.1-0.1-0.2-0.2-0.1-0.3-0.10.20.3-0.2-0.2
Bone: cortical thickness2.84.611.1-2.7-2.8-1.13.0-3.32.9-2.2-2.1-2.8-2.6-1.7-1.71.61.01.7-1.5-1.11.01.6
Bone: cortical thickness0.80.92.6-1.3-1.4-0.91.5-1.61.4-1.0-1.0-1.2-1.20.10.10.60.20.6-0.5-0.20.10.5
Bone: cortical tissue density0.60.91.8-1.0-1.1-0.51.2-1.11.3-1.2-1.2-0.9-1.3-0.6-0.61.00.50.9-0.7-0.90.30.7
Condit. Reinf. active minus inactive responses0.40.50.9-0.30.4-0.4-0.60.4-0.70.80.80.80.80.30.3-0.9-0.9-0.90.90.5-0.7-0.8
Condit. Reinf. active-inactive response ratio0.40.41.4-0.00.50.1-0.70.5-0.81.21.20.60.7-0.2-0.2-0.9-0.5-0.80.70.2-0.4-0.6
Condit. Reinf. active responses0.10.10.3-0.10.40.1-0.40.1-0.40.40.40.60.4-0.1-0.1-0.3-0.3-0.30.30.0-0.2-0.3
Condit. Reinf. inactive responses0.10.10.30.30.20.3-0.0-0.10.1-0.6-0.60.1-0.2-0.1-0.10.50.30.4-0.4-0.30.30.3
Incentive salience index mean0.30.30.8-0.30.4-0.3-0.50.2-0.60.50.50.90.70.20.2-0.8-0.8-0.80.80.4-0.6-0.7
Condit. Reinf. lever presses0.00.00.1-0.00.10.1-0.1-0.2-0.1-0.4-0.40.3-0.1-0.3-0.30.00.00.1-0.1-0.30.10.1
Condit. Reinf. active minus inactive responses1.21.93.70.91.60.1-1.71.5-1.71.11.01.91.91.51.5-1.3-1.0-1.31.31.3-1.0-1.3
Condit. Reinf. active-inactive response ratio1.11.74.71.72.21.0-2.01.6-1.91.31.21.91.80.70.7-0.8-0.3-0.80.70.5-0.2-0.7
Condit. Reinf. active responses1.42.03.60.21.0-0.8-1.21.3-1.30.50.51.81.81.81.8-1.4-1.6-1.51.61.9-1.7-1.7
Condit. Reinf. inactive responses0.71.12.8-1.2-0.7-1.70.30.10.0-0.3-0.20.40.41.11.1-1.0-1.5-1.11.31.6-1.6-1.3
Condit. Reinf. lever presses1.11.63.4-0.70.1-1.2-0.40.5-0.71.01.00.81.21.61.6-1.6-1.6-1.61.61.8-1.5-1.5
Condit. Reinf. lever reinforcers received1.52.14.2-0.00.8-1.1-1.01.2-1.20.30.31.81.71.71.7-1.5-1.7-1.61.72.1-1.8-1.8
Conditioned reinforcement - actives0.20.81.60.3-0.10.90.4-0.40.6-1.0-0.8-0.6-0.7-1.0-1.01.31.21.2-1.2-0.61.11.1
Conditioned reinforcement - inactives0.61.64.21.92.01.7-1.81.8-1.61.31.11.51.4-1.3-1.3-0.20.5-0.2-0.0-0.20.50.0
Conditioned locomotion2.84.213.33.63.03.6-2.42.1-1.81.61.81.11.1-1.8-1.80.82.10.9-1.3-1.62.21.3
Patch foraging indifference point 0 sec0.00.10.50.60.30.1-0.30.7-0.3-0.3-0.30.40.20.50.50.00.0-0.00.10.3-0.1-0.1
Patch foraging indifference point AUC0.51.13.6-1.1-1.1-0.41.2-1.51.2-1.8-1.9-1.1-1.2-0.4-0.40.80.50.8-0.7-0.70.50.7
Delay disc. indifference point, 0s delay2.12.43.3-0.10.8-0.8-1.21.4-1.51.61.51.81.71.81.8-1.8-1.5-1.81.81.7-1.6-1.8
Delay disc. indifference point, 16s delay0.50.71.81.21.20.9-1.11.0-1.11.31.30.70.8-0.5-0.5-0.50.2-0.40.2-0.30.2-0.2
Delay disc. indifference point, 2s delay0.70.81.60.80.90.1-1.11.3-1.11.01.01.21.10.40.4-0.9-0.6-0.90.80.7-0.6-0.8
Delay disc. indifference point, 24s delay0.20.41.0-0.1-0.7-0.00.8-0.80.8-0.5-0.4-1.0-1.0-0.2-0.20.60.40.6-0.6-0.80.40.6
Delay disc. indifference point, 4s delay0.40.40.90.10.3-0.5-0.40.5-0.50.30.20.90.70.50.5-0.7-0.7-0.80.80.8-0.9-0.8
Delay disc. indifference point, 8s delay0.10.20.5-0.2-0.1-0.6-0.10.3-0.30.40.50.30.40.30.3-0.7-0.7-0.70.70.6-0.7-0.7
Indifference point function ln k0.61.86.02.52.12.2-1.71.7-1.31.31.31.00.9-1.1-1.10.41.10.4-0.6-0.71.10.6
Indifference point function log k0.61.86.02.52.12.2-1.71.7-1.31.31.31.00.9-1.1-1.10.41.10.4-0.6-0.71.10.6
Patch foraging total patch changes 0 sec0.10.21.30.2-0.30.00.40.10.4-1.2-1.1-0.3-0.4-0.1-0.10.60.40.5-0.4-0.10.20.4
Patch foraging total patch changes 12 sec1.11.53.5-1.9-1.8-1.71.6-1.41.4-1.7-1.8-1.0-1.01.11.10.2-0.60.10.20.6-0.7-0.2
Patch foraging total patch changes 18 sec0.10.31.6-0.7-0.7-0.80.4-0.20.3-1.3-1.2-0.0-0.20.20.2-0.2-0.4-0.30.40.5-0.5-0.4
Patch foraging total patch changes 24 sec0.30.92.7-1.0-1.4-0.71.3-1.21.2-1.5-1.7-1.2-1.0-0.1-0.10.60.20.6-0.40.00.20.4
Patch foraging total patch changes 6 sec0.71.14.4-1.0-0.9-1.50.5-0.30.2-0.3-0.30.00.12.12.1-0.8-1.1-0.91.01.3-1.2-1.0
Patch foraging time to switch 0 sec0.93.36.2-1.3-0.3-2.1-0.40.7-0.81.81.91.11.31.91.9-2.4-2.5-2.32.32.1-2.4-2.3
Patch foraging water rate 0 sec1.35.110.42.71.13.1-0.2-0.10.4-1.3-1.4-1.0-1.1-2.7-2.72.73.22.7-2.9-2.63.12.8
Patch foraging water rate 12 sec1.45.816.53.41.94.1-1.00.3-0.40.40.4-0.8-0.5-2.8-2.82.43.52.5-2.8-2.93.62.8
Patch foraging water rate 18 sec0.51.03.01.71.21.7-0.80.4-0.5-0.10.00.30.2-1.1-1.10.91.40.9-1.0-1.01.31.0
Patch foraging water rate 24 sec2.53.67.12.10.62.50.0-0.40.5-0.8-0.7-1.0-1.0-2.7-2.72.22.52.3-2.4-2.22.62.3
Patch foraging water rate 6 sec2.13.16.61.40.32.10.3-0.50.7-1.2-1.2-1.3-1.1-2.6-2.62.02.42.1-2.2-1.92.42.2
Seeking ratio, delayed vs. immediate footshock0.60.91.7-0.30.3-0.7-0.60.7-0.70.80.81.11.01.11.1-1.0-1.1-1.01.11.3-1.1-1.1
Distance traveled before self-admin0.20.51.0-0.20.3-0.4-0.50.6-0.70.90.70.60.90.60.6-1.0-0.9-0.90.90.9-0.7-0.9
Distance traveled after self-admin0.10.20.7-0.10.0-0.1-0.20.1-0.30.70.60.10.50.80.8-0.4-0.2-0.40.30.5-0.2-0.3
Extensor digitorum longus weight2.610.230.9-5.6-5.4-4.34.8-4.64.2-3.7-3.7-3.4-3.20.30.30.6-1.00.6-0.11.1-1.10.1
Bone: elastic displacement2.43.14.70.1-0.81.21.2-1.31.5-1.5-1.6-1.7-1.9-2.1-2.12.02.02.1-2.1-2.22.12.1
Bone: elastic work1.31.84.2-1.5-1.9-0.61.9-1.91.9-1.1-1.1-2.0-1.8-0.5-0.51.00.71.1-1.0-0.90.71.0
Bone: endosteal estimation1.33.28.42.01.90.8-2.22.2-2.32.92.91.72.10.80.8-1.8-0.8-1.61.41.0-0.6-1.3
Bone: endosteal perimeter2.25.410.62.52.91.1-3.23.3-3.22.82.82.93.00.60.6-2.1-1.2-2.11.81.4-1.0-1.8
Epididymis fat weight1.15.415.64.03.63.9-3.12.6-2.62.12.21.81.8-2.0-2.00.21.80.4-0.8-1.71.90.8
Delta time in closed arm before/after self-admin0.70.71.6-1.1-1.3-0.81.3-1.21.2-0.8-1.0-1.2-0.9-0.1-0.10.50.00.5-0.40.10.10.4
Delta time in open arm before/after self-admin0.40.51.10.30.7-0.1-0.70.4-0.70.91.10.80.71.11.1-0.7-0.6-0.70.70.4-0.6-0.7
Diff in mean of infusions in LGA sessions0.20.41.2-1.1-0.8-0.70.9-1.00.8-0.9-0.8-0.4-0.6-0.1-0.10.4-0.10.3-0.10.5-0.20.1
Delay discount exponential model param0.40.61.0-0.2-0.30.60.5-0.70.7-0.8-0.8-0.8-0.8-0.6-0.61.00.91.0-1.0-0.80.91.0
Extinction: sum of active levers before priming0.60.92.7-1.2-0.8-1.60.5-0.50.2-0.0-0.10.10.30.80.8-1.1-1.5-1.11.21.3-1.4-1.1
Active lever presses in extinction session 60.60.61.7-1.1-1.2-0.71.2-1.31.0-0.9-0.8-0.8-1.1-0.2-0.20.40.30.4-0.3-0.30.10.3
Bone: final force0.40.62.1-1.3-1.1-1.40.8-0.60.50.00.0-0.2-0.10.40.4-0.7-1.0-0.70.81.0-0.9-0.7
Bone: final moment0.40.61.9-1.3-1.1-1.40.8-0.70.50.10.1-0.3-0.10.40.4-0.7-0.9-0.60.71.0-0.8-0.7
Food consumed during 24 hour testing period0.20.41.00.70.51.0-0.30.1-0.20.90.9-0.20.1-0.6-0.60.30.70.4-0.5-0.60.90.6
Glucose2.54.08.31.82.60.5-2.72.7-2.62.02.12.92.61.21.2-1.8-1.3-1.81.71.3-1.3-1.8
Heart weight1.52.44.20.41.1-0.5-1.51.7-1.71.41.31.92.01.21.2-1.8-1.5-1.81.82.0-1.5-1.8
Delay discount hyperbolic model param0.50.71.1-0.3-0.40.50.6-0.80.8-0.8-0.8-0.9-0.9-0.6-0.61.10.91.1-1.0-0.90.91.0
Intermittent access intake day 1-15 change0.42.05.22.22.02.3-1.61.3-1.20.50.51.00.8-2.3-2.30.41.30.5-0.7-1.01.30.7
Intermittent access intake escalation0.31.85.32.01.82.1-1.41.1-1.00.20.30.80.7-2.3-2.30.51.30.6-0.8-1.01.30.8
Intermittent access intake escalation 20.91.55.21.91.61.9-1.31.1-1.00.1-0.10.90.6-2.3-2.30.31.00.3-0.6-0.91.00.6
Intermitt. access day 1 inactive lever presses0.00.10.30.10.00.10.1-0.00.1-0.5-0.2-0.2-0.4-0.3-0.30.20.10.2-0.2-0.50.10.2
Intermitt. access day 15 inactive lever presses0.31.53.61.31.70.9-1.71.7-1.71.91.71.51.7-0.2-0.2-0.9-0.2-0.90.70.4-0.2-0.7
Intermitt. access escalation Index0.51.54.41.71.42.1-0.90.7-0.60.70.90.00.0-1.2-1.21.01.61.0-1.2-1.81.61.2
Intermittent access day 1 total infusions1.23.77.51.22.10.3-2.42.7-2.52.22.12.72.50.80.8-2.0-1.3-2.01.81.2-1.3-1.9
Intermittent access day 15 total infusions1.53.69.12.73.02.3-2.82.8-2.61.91.92.32.2-1.6-1.6-0.80.5-0.70.3-0.20.5-0.3
Intermittent access terminal intake (last 3 days)2.03.58.02.32.81.8-2.82.8-2.61.81.82.62.4-1.4-1.4-1.2-0.1-1.10.80.3-0.1-0.8
Intermittent access total infusions2.12.45.71.62.21.0-2.32.4-2.21.61.62.42.2-0.5-0.5-1.2-0.5-1.21.00.6-0.5-1.0
Intermittent access day 1 locomotion0.81.53.01.01.50.3-1.61.7-1.61.51.31.71.60.30.3-1.3-0.8-1.21.10.3-0.8-1.1
Intermittent access day 15 total locomotion0.93.59.12.83.02.2-2.82.8-2.62.01.92.32.3-1.2-1.2-0.90.3-0.80.4-0.20.4-0.4
Intermittent access total locomotion4.25.012.23.13.52.3-3.43.3-3.12.52.43.02.8-1.0-1.0-1.30.0-1.20.80.00.1-0.8
Intermittent access standard deviation0.10.61.51.21.20.9-1.11.1-1.01.01.10.90.8-0.7-0.7-0.40.1-0.30.1-0.40.2-0.1
Left kidney weight0.22.05.62.22.42.1-2.11.8-1.81.71.81.31.4-0.5-0.5-0.20.7-0.2-0.1-0.60.80.1
Right kidney weight0.21.34.31.91.82.1-1.30.8-1.00.90.90.60.5-1.0-1.00.61.20.6-0.8-1.21.30.8
Cocaine induced anxiety0.10.31.10.20.3-0.1-0.40.5-0.41.11.00.50.60.60.6-0.5-0.4-0.50.40.5-0.3-0.4
Post-drug Anxiety0.20.20.5-0.7-0.5-0.70.3-0.20.20.10.1-0.1-0.10.50.5-0.4-0.6-0.40.40.3-0.5-0.4
Baseline Anxiety0.30.51.1-0.9-0.9-0.60.9-0.90.9-1.1-1.0-0.8-0.90.10.10.4-0.00.4-0.3-0.5-0.10.3
Tail length0.52.96.3-1.7-2.5-1.02.5-2.32.4-2.1-1.9-2.4-2.2-1.0-1.01.40.81.4-1.2-0.50.61.2
Length with tail1.25.213.1-3.2-3.6-2.43.4-3.23.1-3.2-3.0-2.8-2.5-0.7-0.71.10.01.1-0.70.1-0.10.8
Length without tail0.63.17.5-2.7-2.7-2.12.6-2.52.4-2.7-2.6-1.8-1.8-0.1-0.10.8-0.30.7-0.40.2-0.40.4
Times rat made contact with spout0.70.81.5-0.6-0.1-1.1-0.10.2-0.30.90.90.50.71.21.2-1.0-1.2-1.01.11.2-1.1-1.1
Lifetime Intake1.01.33.21.01.60.7-1.71.8-1.61.11.01.81.6-0.4-0.4-0.9-0.4-0.90.80.5-0.4-0.8
Liver weight, left0.50.82.00.60.01.00.2-0.10.4-0.5-0.5-0.7-0.9-1.2-1.21.01.21.1-1.1-1.41.21.1
Liver weight, right0.51.02.51.30.81.6-0.50.3-0.2-0.2-0.10.0-0.3-1.4-1.41.01.31.0-1.1-1.21.31.1
Locomotor activity0.50.72.51.51.01.6-0.70.2-0.50.40.40.00.0-0.7-0.70.51.00.6-0.8-1.21.30.8
Locomotor testing distance0.40.93.01.61.01.7-0.60.2-0.40.50.5-0.2-0.2-0.5-0.50.71.20.8-1.0-1.61.51.0
Locomotor testing rearing0.31.22.81.41.61.1-1.51.3-1.51.71.61.21.20.60.6-0.7-0.0-0.60.4-0.10.2-0.4
Locomotion in novel chamber2.43.29.13.03.02.3-2.62.6-2.42.22.02.21.9-0.6-0.6-0.40.6-0.40.2-0.20.6-0.2
Locomotion in novel chamber post-restriction0.72.05.82.42.32.1-2.01.9-1.71.71.51.51.2-0.6-0.6-0.10.7-0.0-0.2-0.80.80.2
Fecal boli incidents, locomotor time 10.00.10.20.40.40.3-0.30.2-0.20.40.40.10.30.00.00.00.30.0-0.10.20.20.1
Change in fecal boli incidents, locomotor task0.10.10.3-0.3-0.4-0.60.3-0.10.2-0.2-0.2-0.0-0.10.50.5-0.1-0.4-0.10.20.2-0.5-0.3
Time >=10cm from walls, locomotor time 12.32.85.51.41.90.4-2.02.2-2.12.32.42.02.21.31.3-1.6-0.9-1.61.41.3-1.0-1.4
Bouts of movement, locomotor time 11.01.32.6-0.6-1.5-0.61.6-1.41.6-1.6-1.6-1.4-1.5-0.3-0.31.20.61.1-0.9-0.50.40.9
Total resting periods, locomotor time 10.80.91.6-0.2-1.0-0.21.2-1.11.3-1.2-1.2-1.1-1.3-0.4-0.41.10.71.0-0.9-0.60.60.9
Rest time, locomotor task time 10.71.23.71.61.11.9-0.60.3-0.30.60.6-0.1-0.3-0.9-0.90.91.61.0-1.2-1.61.61.2
Distance moved, locomotor task time 10.41.12.0-0.20.4-0.9-0.60.8-0.80.50.51.31.20.90.9-1.3-1.3-1.31.41.4-1.4-1.4
Vertical activity count, locomotor time 10.10.81.60.91.20.4-1.21.2-1.21.11.11.11.20.00.0-0.8-0.5-0.80.70.3-0.4-0.7
Time >=10cm from walls, locomotor time 20.10.31.00.70.20.60.1-0.20.2-0.2-0.0-0.3-0.3-1.0-1.00.60.80.6-0.6-0.70.60.6
Bouts of movement, locomotor time 20.10.30.6-0.5-0.8-0.70.8-0.60.7-0.8-0.7-0.6-0.70.00.00.2-0.00.1-0.1-0.3-0.20.1
Total resting periods, locomotor time 20.00.10.2-0.2-0.3-0.50.4-0.10.3-0.3-0.2-0.2-0.30.30.3-0.1-0.1-0.10.1-0.2-0.3-0.1
Rest time, locomotor task time 21.22.05.41.51.91.1-1.91.8-1.92.32.31.61.60.80.8-1.0-0.2-0.90.70.1-0.1-0.7
Distance moved, locomotor task time 21.01.33.1-0.8-1.3-0.51.4-1.51.4-1.8-1.8-1.3-1.3-0.9-0.91.00.51.0-0.8-0.30.40.8
Vertical activity count, locomotor time 21.22.74.2-0.3-1.20.61.5-1.71.7-1.7-1.7-2.1-1.9-1.9-1.91.81.61.8-1.8-1.61.61.8
Light reinforcement 10.10.51.50.90.81.2-0.50.4-0.3-0.1-0.10.10.0-0.9-0.90.60.90.6-0.7-0.60.90.7
Light reinforcement 20.61.44.21.71.62.0-1.20.7-0.80.20.30.60.4-1.9-1.90.61.40.7-0.9-1.11.30.9
Bone: marrow area1.33.38.52.02.00.8-2.22.3-2.32.92.91.82.20.80.8-1.8-0.9-1.71.41.0-0.6-1.3
Bone: maximum diameter0.10.31.10.50.40.7-0.40.1-0.40.80.8-0.10.3-1.1-1.1-0.10.40.0-0.2-0.30.60.3
Bone: maximum force1.42.85.3-1.2-0.5-2.0-0.10.3-0.71.51.50.61.31.71.7-2.2-2.3-2.22.22.3-2.1-2.1
Bone: maximum moment1.32.54.7-1.2-0.6-1.9-0.10.2-0.61.51.60.41.21.71.7-2.1-2.1-2.02.02.2-1.9-2.0
Mean time between licks in bursts0.10.41.4-1.2-1.1-1.01.0-0.80.9-0.7-0.7-0.5-0.60.20.20.3-0.20.2-0.00.5-0.4-0.0
Mean num. licks in bursts0.00.10.2-0.20.1-0.3-0.10.1-0.20.0-0.00.30.20.10.1-0.2-0.4-0.30.30.4-0.4-0.3
Cd content in liver0.70.82.61.61.41.3-1.21.2-1.01.31.10.80.7-0.5-0.5-0.00.50.0-0.1-0.50.40.1
Co content in liver1.82.13.80.50.01.50.5-1.00.9-1.0-0.9-1.1-1.3-1.9-1.91.81.91.8-1.9-1.91.81.9
Cu content in liver0.10.10.40.2-0.10.30.1-0.10.1-0.1-0.2-0.3-0.3-0.6-0.60.10.30.2-0.3-0.60.30.3
Fe content in liver0.10.20.6-0.2-0.3-0.20.4-0.40.3-0.7-0.7-0.0-0.3-0.8-0.80.2-0.00.2-0.1-0.0-0.00.1
K content in liver0.40.41.0-0.5-0.1-0.7-0.10.0-0.31.00.90.30.40.40.4-0.9-0.9-0.90.80.7-0.7-0.8
Mg content in liver0.60.72.70.60.90.4-1.00.8-1.01.61.60.70.90.60.6-0.8-0.4-0.70.60.2-0.2-0.5
Mn content in liver0.70.72.9-1.7-1.4-1.41.1-1.20.9-0.7-0.8-0.6-0.50.30.3-0.2-0.6-0.20.40.6-0.7-0.4
Na content in liver0.50.61.2-0.0-0.30.60.5-0.70.60.10.1-1.1-0.8-0.7-0.70.81.00.9-0.9-0.91.01.0
Rb content in liver1.01.13.21.21.60.5-1.61.5-1.51.00.81.81.40.10.1-0.8-0.6-0.90.80.6-0.7-0.9
Se content in liver0.30.30.70.50.5-0.0-0.70.8-0.70.50.40.80.60.20.2-0.7-0.5-0.70.60.3-0.5-0.6
Sr content in liver1.11.02.6-1.4-1.6-0.71.5-1.61.4-0.9-0.7-1.6-1.1-0.1-0.10.60.50.6-0.6-0.20.40.6
Zn content in liver0.50.51.5-0.7-1.0-0.21.0-1.01.0-0.7-0.5-1.2-1.1-0.3-0.30.60.40.6-0.6-0.60.40.6
Bone: minimum diameter1.93.66.51.62.00.3-2.32.2-2.42.52.52.32.60.60.6-2.1-1.4-2.01.81.5-1.2-1.8
Time in familiar zone, hab. session 10.70.72.30.80.90.6-1.11.1-1.11.51.50.71.2-0.1-0.1-0.9-0.3-0.80.60.5-0.1-0.5
Time in novel zone, hab. session 10.20.30.7-0.2-0.4-0.30.5-0.50.6-0.8-0.8-0.3-0.70.70.70.60.20.5-0.3-0.4-0.00.3
Total zone transitions, hab. session 10.30.41.1-0.7-0.2-0.5-0.0-0.3-0.31.11.1-0.20.50.60.6-1.0-0.6-0.80.70.8-0.3-0.6
Total locomotion distance, hab. session 10.50.72.20.91.11.0-1.20.8-1.21.51.50.51.0-0.2-0.2-0.8-0.0-0.70.4-0.10.3-0.3
Locomotion velocity, hab. session 10.20.31.00.40.70.7-0.80.3-0.81.01.00.30.6-0.2-0.2-0.60.0-0.50.2-0.10.3-0.2
Time in familiar zone, hab. session 20.50.61.2-0.6-1.0-0.31.1-0.91.1-1.1-1.1-0.9-1.00.00.00.80.50.8-0.7-0.40.40.7
Time in novel zone, hab. session 20.80.91.40.10.6-0.5-0.90.9-1.01.01.01.01.10.80.8-1.1-1.1-1.11.11.1-1.1-1.2
Total zone transitions, hab. session 23.64.67.9-0.90.2-2.0-0.80.9-1.41.71.71.51.92.72.7-2.8-2.7-2.72.82.8-2.6-2.7
Total locomotion distance, hab. session 21.41.93.10.20.8-0.5-1.21.0-1.41.31.31.41.51.61.6-1.7-1.4-1.71.61.4-1.3-1.6
Locomotion velocity, hab. session 21.41.93.00.51.1-0.2-1.41.2-1.61.51.51.51.71.41.4-1.7-1.3-1.71.51.2-1.1-1.5
Novel to familiar place preference ratio0.30.40.8-0.6-0.2-0.8-0.10.2-0.20.50.50.30.40.80.8-0.7-0.8-0.70.80.7-0.9-0.8
Novelty place preference0.30.40.7-0.30.1-0.5-0.40.5-0.50.70.70.50.50.70.7-0.7-0.8-0.80.80.7-0.8-0.8
Time in novel zone, NPP test0.30.40.8-0.30.1-0.6-0.40.5-0.50.60.60.50.50.80.8-0.7-0.8-0.80.80.7-0.9-0.8
Total zone transitions, NPP test1.11.74.4-0.7-0.3-1.4-0.10.2-0.50.70.70.50.92.12.1-1.6-1.6-1.51.61.8-1.5-1.5
Total locomotion distance, NPP test0.50.71.30.50.7-0.1-0.80.6-0.90.80.80.90.91.21.2-1.0-0.7-0.90.90.7-0.6-0.8
Locomotion velocity, NPP test0.40.51.10.50.60.0-0.70.5-0.80.90.90.70.81.11.1-0.8-0.5-0.70.70.5-0.4-0.6
Intraocular pressure0.71.12.50.70.41.40.2-0.50.5-0.4-0.3-0.6-0.8-0.5-0.51.61.61.5-1.5-1.41.51.5
Delta distance traveled before/after self-admin0.10.10.3-0.1-0.30.10.4-0.60.4-0.3-0.2-0.4-0.40.30.30.50.50.4-0.4-0.10.40.4
Delta ambulatory time before/after self-admin0.10.20.7-0.2-0.50.00.6-0.80.6-0.5-0.4-0.5-0.60.20.20.60.50.6-0.5-0.20.40.5
Parametrial fat weight1.33.08.42.92.92.0-2.62.7-2.32.12.02.21.8-0.4-0.4-0.50.2-0.50.3-0.40.2-0.4
Pavlov. Cond. lever latency0.20.20.50.70.40.6-0.10.10.00.00.1-0.1-0.1-0.7-0.70.60.50.5-0.5-0.50.40.5
Pavlov. Cond. magazine entry latency0.81.12.60.20.6-0.5-0.81.2-1.00.60.61.21.01.61.6-1.1-1.0-1.11.10.9-1.1-1.2
Pavlov. Cond. change in total contacts0.50.61.30.50.90.3-1.11.2-1.10.60.61.11.00.70.7-0.7-0.4-0.70.60.4-0.4-0.7
Pavlov. Cond. index score0.10.10.20.10.40.2-0.40.4-0.50.40.40.50.40.50.5-0.4-0.1-0.30.20.0-0.0-0.2
Pavlov. Cond. latency score0.10.20.4-0.00.3-0.0-0.40.5-0.50.30.30.60.40.60.6-0.5-0.3-0.50.50.2-0.3-0.5
Pavlov. Cond. lever contacts0.10.10.4-0.30.0-0.2-0.20.2-0.30.20.20.40.30.70.7-0.5-0.4-0.50.40.3-0.3-0.4
Pavlov. Cond. magazine entry number0.00.00.2-0.2-0.2-0.20.2-0.40.20.00.0-0.2-0.1-0.4-0.4-0.0-0.2-0.00.00.2-0.1-0.0
Pavlov. Cond. intertrial magazine entries0.60.71.80.20.00.90.3-0.50.4-0.0-0.0-0.8-0.6-1.3-1.30.91.10.9-1.0-1.01.11.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.10.40.2-0.50.4-0.50.40.40.50.40.50.5-0.5-0.1-0.40.30.1-0.1-0.3
Pavlov. Cond. response bias0.00.00.10.10.20.3-0.20.2-0.20.20.20.10.10.40.4-0.10.2-0.0-0.0-0.20.20.1
Pavlov. Cond. lever latency0.10.10.70.0-0.2-0.20.2-0.00.3-0.8-0.8-0.1-0.3-0.1-0.10.30.00.2-0.1-0.1-0.10.1
Pavlov. Cond. magazine entry latency1.72.45.8-1.7-0.9-2.40.4-0.4-0.00.20.30.60.62.12.1-1.7-2.2-1.71.92.1-2.2-1.9
Pavlov. Cond. change in total contacts0.41.01.8-0.30.3-0.8-0.50.7-0.70.90.90.81.01.01.0-1.3-1.2-1.31.31.3-1.2-1.3
Pavlov. Cond. index score0.60.91.7-0.8-0.2-1.2-0.10.1-0.40.70.70.50.71.11.1-1.2-1.3-1.21.21.2-1.2-1.2
Pavlov. Cond. latency score0.40.71.3-0.6-0.2-1.0-0.10.1-0.40.70.70.40.60.90.9-1.1-1.1-1.11.11.0-1.0-1.0
Pavlov. Cond. lever contacts0.10.10.7-0.10.30.0-0.30.1-0.30.80.90.20.40.20.2-0.4-0.2-0.40.30.3-0.1-0.2
Pavlov. Cond. magazine entry number2.02.76.92.01.22.6-0.60.5-0.1-0.2-0.3-0.4-0.5-2.1-2.11.72.31.8-2.0-2.12.31.9
Pavlov. Cond. intertrial magazine entries0.30.61.71.10.61.3-0.40.6-0.1-0.2-0.2-0.1-0.2-0.7-0.70.91.10.9-0.9-0.91.00.9
Pavlov. Cond. lever-magazine prob. diff.0.71.01.9-1.0-0.4-1.40.1-0.0-0.20.60.60.40.61.31.3-1.3-1.4-1.21.31.3-1.3-1.3
Pavlov. Cond. response bias0.71.02.0-0.8-0.1-1.2-0.20.1-0.40.70.70.60.81.31.3-1.2-1.3-1.21.31.4-1.2-1.2
Time in closed arm before self-admin0.61.01.91.01.20.4-1.21.3-1.21.21.41.31.01.41.4-0.7-0.3-0.70.70.2-0.5-0.7
Time in closed arm after self-admin0.00.00.20.10.00.20.1-0.00.2-0.0-0.10.0-0.20.20.20.40.30.4-0.3-0.00.20.3
Time in open arm before self-admin1.11.32.8-1.1-1.3-0.31.3-1.11.3-1.5-1.7-1.6-1.2-1.6-1.60.70.40.8-0.8-0.70.60.8
Time in open arm after self-admin0.20.20.7-0.8-0.6-0.80.4-0.40.3-0.2-0.3-0.4-0.1-0.0-0.0-0.4-0.6-0.40.40.1-0.5-0.4
Bone: periosteal estimation0.20.52.70.70.60.5-0.70.6-0.81.61.60.30.7-0.4-0.4-0.8-0.2-0.60.40.20.1-0.4
Bone: periosteal perimeter0.40.81.60.50.8-0.1-1.01.0-1.10.90.91.11.30.30.3-1.1-0.8-1.11.01.0-0.8-1.0
Bone: post-yield work6.411.017.60.72.0-1.4-2.93.1-3.43.53.53.33.83.33.3-4.2-3.6-4.14.03.4-3.3-3.9
Progressive ratio test 1 active lever presses0.10.10.4-0.2-0.10.10.2-0.10.2-0.7-0.6-0.1-0.2-0.1-0.10.50.40.4-0.3-0.00.20.3
Progressive ratio test 1 breakpoint0.10.10.5-0.2-0.10.10.2-0.20.3-0.7-0.6-0.1-0.2-0.0-0.00.50.40.5-0.4-0.10.20.3
Progressive ratio test 1 inactive lever presses0.00.00.1-0.2-0.00.10.0-0.00.1-0.3-0.1-0.1-0.0-0.1-0.10.20.20.2-0.2-0.20.10.1
Progressive ratio test 2 active lever presses0.50.82.01.11.41.2-1.31.3-1.20.70.91.11.1-0.7-0.7-0.30.3-0.20.1-0.10.3-0.1
Progressive ratio test 2 breakpoint0.50.71.81.11.31.2-1.21.2-1.10.60.81.01.0-0.7-0.7-0.20.4-0.10.0-0.10.3-0.0
Progressive ratio test 2 inactive lever presses1.34.09.72.93.12.7-2.92.8-2.62.22.22.12.2-1.8-1.8-0.60.8-0.50.1-0.60.9-0.1
Incentive Sensitization - Responses0.20.60.9-0.20.4-0.4-0.60.8-0.70.60.90.90.90.60.6-1.0-0.9-1.01.00.9-0.9-1.0
Incentive Sensitization - Breakpoint0.30.61.00.00.6-0.2-0.81.0-0.90.71.01.01.00.50.5-0.9-0.7-0.90.90.8-0.8-0.9
Sum of active levers in priming session hrs 5-63.23.04.80.3-0.81.21.2-1.71.5-1.2-1.3-2.0-1.7-2.0-2.02.02.12.1-2.2-1.92.22.2
Progressive ratio1.64.69.8-1.0-0.0-2.3-0.71.2-1.21.21.01.91.92.62.6-2.5-2.9-2.62.83.1-2.9-2.8
Food seeking constrained by brief footshock0.10.20.6-0.8-0.5-0.60.20.00.1-0.1-0.10.1-0.10.40.4-0.4-0.5-0.40.40.4-0.6-0.4
Seeking ratio, punishment vs. effort1.22.66.20.80.11.90.4-0.70.7-0.6-0.5-1.4-1.4-2.0-2.01.82.21.8-2.0-2.52.22.1
Retroperitoneal fat weight2.812.435.15.95.85.5-5.04.5-4.23.83.93.22.9-2.2-2.20.12.20.2-0.8-2.12.30.8
Reaction time number correct0.20.61.5-0.5-0.7-0.00.8-1.10.8-1.2-1.2-0.8-0.6-0.7-0.70.70.60.7-0.7-0.10.60.7
Reaction time mean minus median0.21.23.6-1.6-0.8-1.60.6-0.50.30.20.2-0.10.31.91.9-0.9-1.4-0.91.01.5-1.2-1.0
Reaction time mean minus median AUC0.10.61.9-1.4-0.9-1.10.8-1.00.6-0.0-0.0-0.5-0.11.21.2-0.2-0.7-0.20.31.0-0.5-0.3
Reaction time num false alarms0.71.11.8-0.2-0.60.40.9-1.01.0-1.0-1.1-1.2-1.2-1.4-1.41.11.01.2-1.2-1.11.11.2
Reaction time num false alarms AUC0.51.12.5-0.9-1.2-0.31.3-1.31.3-1.5-1.6-1.2-1.3-1.1-1.11.00.40.9-0.9-0.70.50.9
Reaction time trials correct on left0.20.61.5-0.5-0.7-0.00.8-1.10.8-1.2-1.2-0.8-0.6-0.7-0.70.70.60.7-0.7-0.10.60.7
Reaction time trials on left0.20.71.7-0.6-0.8-0.10.9-1.20.9-1.3-1.3-0.9-0.7-0.7-0.70.80.60.8-0.7-0.10.60.7
Reaction time mean0.30.82.50.10.4-0.3-0.50.5-0.61.21.20.50.81.61.6-0.8-0.7-0.80.81.1-0.6-0.8
Reaction time mean AUC0.40.92.10.20.5-0.3-0.70.7-0.81.21.20.71.01.51.5-0.9-0.8-0.90.91.1-0.7-0.9
Median of all reaction times0.61.02.30.50.7-0.1-0.90.9-1.01.41.50.81.01.51.5-0.9-0.7-0.90.91.0-0.7-0.9
Reaction time omissions0.60.93.2-1.8-1.3-1.61.2-1.21.0-0.6-0.6-0.4-0.41.11.1-0.2-0.8-0.20.50.9-0.8-0.5
Reaction time false alarm rate0.40.51.0-0.4-0.7-0.00.8-0.70.9-0.8-0.9-0.8-1.0-0.9-0.90.70.40.7-0.7-0.80.50.7
Reaction time premature initiation rate1.01.53.8-1.9-1.9-1.91.7-1.61.4-1.5-1.4-1.3-1.20.70.7-0.1-0.8-0.10.30.2-0.8-0.3
Reaction time premature initiations0.82.56.0-2.2-2.5-1.82.3-2.42.0-2.3-2.2-1.9-1.70.20.20.5-0.30.5-0.30.0-0.30.3
Std. dev. reaction times0.20.72.5-0.7-0.3-1.00.2-0.10.00.50.40.10.41.61.6-0.6-1.0-0.60.71.3-0.9-0.8
Reaction time trials completed0.20.71.7-0.6-0.8-0.10.9-1.20.9-1.3-1.3-0.9-0.7-0.7-0.70.80.60.8-0.7-0.10.60.7
Reaction time trials AUC0.10.51.4-0.5-0.7-0.10.8-1.00.8-1.2-1.1-0.8-0.6-0.6-0.60.60.60.7-0.6-0.10.60.6
Run reversals in cocaine runway, females1.11.23.8-0.6-0.3-1.40.00.2-0.20.50.70.70.71.91.9-1.0-1.3-1.11.21.5-1.4-1.2
Run reversals in cocaine runway, males0.60.71.2-0.2-0.20.30.7-0.90.9-0.9-0.9-0.8-1.0-0.5-0.51.10.91.0-1.0-1.00.81.0
Latency to leave start box in cocaine runway1.01.32.20.40.8-0.2-1.21.3-1.31.31.41.21.40.90.9-1.5-1.1-1.41.31.1-1.0-1.3
Latency to leave start box in cocaine runway, F0.91.21.90.30.7-0.3-1.01.1-1.11.21.31.11.31.11.1-1.4-1.0-1.31.20.9-1.0-1.2
Latency to leave start box in cocaine runway, M0.00.00.2-0.1-0.0-0.1-0.20.1-0.20.1-0.00.10.3-0.0-0.0-0.3-0.2-0.30.30.4-0.2-0.3
Std. dev. time between licks in bursts1.12.04.3-0.7-1.3-0.21.6-1.51.7-2.0-2.1-1.2-1.6-1.5-1.51.61.01.5-1.3-0.80.81.3
Total sessions with >9 infusions0.10.20.6-0.6-0.2-0.60.10.1-0.0-0.4-0.50.40.30.30.3-0.2-0.5-0.30.50.8-0.6-0.5
Short access day 1 total inactive lever presses0.40.72.01.41.41.3-1.21.1-1.01.11.20.70.8-0.2-0.2-0.00.60.0-0.2-0.20.60.2
Short access day 10 total inactive lever presses0.00.10.7-0.00.00.1-0.20.1-0.20.50.9-0.2-0.10.10.1-0.3-0.2-0.30.1-0.2-0.0-0.1
Short access day 1 total infusions0.20.41.20.81.10.8-1.01.0-0.90.70.60.90.7-0.4-0.4-0.30.1-0.30.2-0.20.1-0.2
Short access day 10 total infusions1.11.84.1-0.00.8-0.8-1.11.5-1.30.60.72.01.61.11.1-1.4-1.4-1.51.61.7-1.6-1.7
Short access total infusions0.40.51.1-0.30.4-0.4-0.60.8-0.70.40.31.10.90.50.5-0.8-0.8-0.80.90.9-0.9-0.9
Short access day 1 locomotion0.30.61.30.91.20.7-1.11.1-1.00.91.01.01.0-0.3-0.3-0.40.0-0.40.30.10.0-0.3
Short access day 10 total locomotion0.20.91.90.81.10.2-1.21.3-1.21.00.91.41.20.70.7-0.8-0.6-0.90.80.4-0.6-0.8
Short access total locomotion0.50.71.70.91.20.5-1.21.3-1.20.80.81.31.10.00.0-0.6-0.3-0.60.60.2-0.3-0.6
One hour access (0.3 mA shock)1.92.35.72.12.42.0-2.22.1-2.01.71.81.61.7-1.1-1.1-0.50.5-0.40.2-0.40.6-0.1
Compulsive drug intake1.62.45.6-1.9-2.3-1.42.3-2.42.2-1.6-1.6-2.2-1.91.01.01.20.31.1-0.8-0.10.20.8
One hour access (shock baseline)1.43.79.62.93.12.7-2.82.7-2.51.71.72.22.0-1.9-1.9-0.50.7-0.40.0-0.80.8-0.0
Social response proportion0.40.51.3-0.4-0.1-1.10.10.2-0.0-0.1-0.20.60.41.11.1-0.5-1.0-0.60.80.9-1.1-0.8
Social responses0.20.20.4-0.5-0.5-0.40.6-0.60.6-0.5-0.6-0.4-0.30.50.50.40.10.4-0.20.20.00.2
Social time0.20.31.2-0.9-0.6-0.70.5-0.40.5-0.3-0.4-0.4-0.21.11.1-0.0-0.3-0.10.20.4-0.4-0.2
Soleus weight1.54.514.03.72.53.7-1.61.3-1.00.70.70.30.2-2.1-2.11.92.81.9-2.1-2.42.72.1
Bone: stiffness1.42.55.6-0.7-0.1-1.7-0.50.6-0.91.41.41.01.51.21.2-2.2-2.2-2.12.12.4-2.0-2.1
Tibialis anterior weight4.013.936.2-5.7-6.0-3.15.6-6.05.1-3.6-3.6-5.3-4.4-1.0-1.01.90.82.0-1.7-0.50.81.8
Time to tail flick, vehicle, before self-admin1.11.43.8-0.30.3-1.3-0.51.0-0.70.70.61.41.10.90.9-1.3-1.6-1.41.51.9-1.7-1.6
Time to tail flick, vehicle, after self-admin0.91.73.5-1.7-0.6-1.80.00.1-0.30.60.60.80.81.41.4-1.6-1.9-1.61.71.7-1.8-1.7
Time to tail flick, test, before self-admin2.12.44.20.61.3-0.2-1.61.9-1.81.81.72.02.01.41.4-1.6-1.2-1.61.61.6-1.3-1.6
Time to tail flick, test, after self-admin0.10.10.3-0.5-0.40.00.30.00.3-0.3-0.2-0.4-0.2-0.1-0.10.30.20.3-0.3-0.10.20.3
Delta time to tail flick, vehicle, before/after SA0.30.41.6-1.3-0.7-0.90.3-0.40.1-0.10.1-0.20.20.80.8-0.7-0.7-0.60.60.5-0.6-0.6
Delta time to tail flick, test, before/after SA3.74.68.0-1.2-2.00.32.3-2.32.5-2.3-2.3-2.8-2.6-1.9-1.92.41.82.4-2.3-1.81.82.3
Tibia length0.61.72.5-0.4-0.90.51.2-1.51.2-1.2-1.3-1.4-1.3-1.6-1.61.31.31.4-1.4-1.21.51.5
Ambulatory time before self-admin0.30.81.40.10.6-0.4-0.80.9-0.90.90.71.01.10.40.4-1.2-1.1-1.21.11.0-1.0-1.1
Ambulatory time after self-admin0.81.32.70.91.30.4-1.41.4-1.51.61.51.41.50.70.7-1.1-0.5-1.10.90.8-0.5-0.9
Bone: tissue strength0.80.83.30.40.90.5-1.00.6-1.11.81.80.51.10.30.3-1.0-0.4-0.90.70.3-0.1-0.6
Total heroin consumption1.61.96.0-2.5-2.2-2.11.9-1.71.7-1.9-1.8-1.2-1.30.30.30.1-0.80.10.20.6-0.9-0.2
Bone: trabecular number2.24.27.2-0.80.3-1.8-1.01.2-1.41.61.61.71.92.72.7-2.7-2.6-2.62.62.4-2.5-2.6
Bone: trabecular spacing0.91.43.40.4-0.21.00.5-0.50.7-1.1-1.1-0.8-1.1-1.8-1.81.41.31.4-1.4-1.51.31.3
Bone: trabecular thickness1.92.65.00.71.2-0.2-1.51.6-1.72.22.21.51.81.81.8-1.9-1.4-1.81.71.4-1.3-1.6
Bone: trabecular tissue density2.54.312.13.22.13.5-1.41.0-0.80.50.50.10.0-3.1-3.11.62.61.7-2.0-2.32.62.0
Water consumed over 24 hours0.40.71.8-1.0-0.8-1.30.4-0.20.00.40.4-0.10.40.80.8-1.0-1.1-1.01.01.4-1.0-1.0
Number of responses in last shaping day0.20.20.7-0.4-0.40.00.4-0.50.5-0.9-0.6-0.7-0.4-0.8-0.80.30.30.3-0.4-0.50.30.4