Clta

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL intron excision ratio chr5_63048312_63052248 0.13 0.09 2.9e-03 0.04 0.07 0.07 0.07 3.3e-02 1.1e-02 7.5e-03 8.7e-03
2 Brain intron excision ratio chr5_63057824_63058782 0.04 0.03 3.3e-04 0.02 0.03 0.03 0.02 3.9e-03 3.8e-04 8.1e-04 2.2e-03
3 RMTg gene expression Clta 0.09 0.07 8.7e-03 0.04 0.07 0.03 0.05 2.6e-02 4.9e-03 4.3e-02 1.9e-02
4 BLA intron excision ratio chr5_63052359_63056566 0.1 0.06 7.3e-06 0.07 0.1 0.09 0.09 9.4e-05 7.7e-06 1.6e-05 2.1e-05
5 Brain intron excision ratio chr5_63056619_63058782 0.03 0.02 3.0e-03 0.03 0.01 0.01 0.02 5.5e-04 1.6e-02 5.9e-02 6.7e-03
6 pVTA intron excision ratio chr5_63052359_63056566 0.05 0.03 6.4e-05 0.06 0.04 0.06 0.05 9.8e-06 3.9e-04 1.2e-05 4.8e-05
7 NAcc intron excision ratio chr5_63056619_63057789 0.08 0.04 1.7e-16 0.1 0.11 0.11 0.09 3.8e-14 2.1e-16 3.5e-16 7.6e-13
8 pVTA intron excision ratio chr5_63052359_63058782 0.05 0.03 1.5e-04 0.06 0.04 0.06 0.05 1.9e-05 2.8e-04 1.1e-05 5.2e-05
9 Brain gene expression Clta 0.03 0.02 8.2e-04 0.03 0.03 0.01 0.02 1.7e-03 1.6e-03 2.3e-02 9.9e-03
10 Brain intron excision ratio chr5_63052359_63056566 0.13 0.06 5.6e-17 0.16 0.17 0.16 0.16 1.0e-14 4.1e-16 2.6e-14 2.4e-14
11 IL intron excision ratio chr5_63041551_63047169 0.12 0.08 3.8e-03 0.04 0.06 0.06 0.04 3.4e-02 1.3e-02 1.9e-02 3.5e-02
12 NAcc intron excision ratio chr5_63052359_63057789 0.14 0.07 0.0e+00 0.2 0.23 0.22 0.23 8.8e-30 6.9e-34 1.7e-33 1.0e-33
13 Adipose gene expression Clta 0.17 0.09 0.0e+00 0.16 0.19 0.19 0.2 1.3e-17 6.2e-21 4.9e-21 2.9e-21
14 Liver intron excision ratio chr5_63048312_63052248 0.1 0.05 6.4e-14 0.13 0.12 0.13 0.13 2.4e-14 1.3e-13 3.6e-14 3.6e-14
15 Liver intron excision ratio chr5_63041551_63047169 0.09 0.05 2.0e-12 0.12 0.1 0.11 0.11 1.1e-12 1.1e-11 5.8e-12 2.7e-12
16 NAcc intron excision ratio chr5_63052359_63056566 0.11 0.06 0.0e+00 0.14 0.13 0.14 0.14 9.8e-21 1.0e-19 3.6e-20 8.4e-21
17 PL mRNA stability Clta 0.03 0.02 2.7e-05 0.04 0.05 0.05 0.05 2.0e-05 7.1e-06 3.9e-06 4.1e-06
18 PL intron excision ratio chr5_63052359_63056566 0.08 0.06 3.0e-08 0.08 0.06 0.05 0.07 1.1e-08 1.3e-07 6.6e-06 3.8e-08
19 NAcc intron excision ratio chr5_63052359_63058782 0.02 0.01 1.3e-03 0.02 0.01 0.01 0.02 3.5e-04 2.0e-03 3.4e-02 1.5e-03
20 PL intron excision ratio chr5_63056619_63057789 0.03 0.02 2.5e-04 0.03 0.03 0.02 0.03 3.4e-04 6.0e-04 5.7e-03 6.5e-04
21 IC intron excision ratio chr5_63052359_63056566 0.09 0.06 3.5e-04 0.07 0.06 0.04 0.05 6.5e-04 1.9e-03 8.6e-03 4.1e-03
22 Adipose mRNA stability Clta 0.25 0.13 0.0e+00 0.19 0.18 0.18 0.19 2.8e-20 7.0e-20 3.8e-20 3.6e-20
23 Brain intron excision ratio chr5_63052359_63058782 0.15 0.1 1.1e-09 0.1 0.11 0.08 0.1 1.9e-09 2.6e-10 1.1e-07 6.0e-10
24 Liver mRNA stability Clta 0.04 0.02 1.4e-04 0.04 0.04 0.03 0.04 3.3e-05 7.6e-05 1.4e-04 6.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density2.13.98.1-2.82.01.7-1.71.81.5-2.0-1.72.2-2.1-2.22.01.9-1.91.9-2.01.81.9-1.91.92.0-2.01.9-2.0
Area under the delay curve0.50.71.21.0-0.8-0.70.8-0.4-0.50.90.5-0.90.91.0-0.9-0.80.6-0.61.0-0.8-0.90.9-1.1-1.01.1-1.01.0
BMI with tail2.38.09.2-2.22.82.8-3.02.62.6-2.9-2.92.9-2.9-2.83.02.9-2.82.8-3.02.92.8-2.92.92.9-2.83.0-2.9
BMI without tail1.26.38.1-1.72.72.7-2.82.52.4-2.7-2.62.5-2.6-2.42.62.6-2.62.6-2.62.52.5-2.52.62.3-2.42.6-2.2
Body weight2.611.616.9-2.63.94.1-4.03.73.6-3.6-3.83.5-3.5-3.13.73.5-3.33.3-3.63.23.3-3.23.12.8-3.03.3-2.8
Weight adjusted by age0.10.31.4-0.50.60.7-0.51.21.0-0.4-0.90.4-0.4-0.30.50.6-0.00.0-0.40.40.1-0.10.20.3-0.10.3-0.3
Bone surface1.12.24.9-2.21.61.5-1.31.61.5-1.5-1.51.6-1.6-1.61.51.5-1.41.4-1.41.41.4-1.31.31.3-1.31.3-1.3
Bone volume1.12.35.2-2.31.51.3-1.31.41.3-1.5-1.41.7-1.6-1.71.51.5-1.41.4-1.41.51.4-1.41.41.5-1.51.4-1.5
Breakpoint value in progressive ratio session1.12.04.32.1-1.0-0.31.0-0.3-0.31.50.5-1.41.41.9-1.0-1.11.7-1.71.4-1.6-1.71.6-1.8-1.51.7-1.31.5
Number of licking bursts1.95.96.5-2.42.52.3-2.52.32.3-2.5-2.32.5-2.5-2.52.42.5-2.32.3-2.52.42.3-2.42.42.5-2.52.4-2.5
Context. condit. distance diff. score0.00.00.1-0.1-0.1-0.10.10.1-0.00.0-0.00.1-0.1-0.10.00.10.1-0.1-0.00.20.1-0.10.10.2-0.20.2-0.2
Locomotion velocity, session 10.30.41.90.50.41.1-0.41.41.20.1-1.1-0.10.10.60.30.20.4-0.40.1-0.1-0.40.6-0.5-0.60.6-0.30.6
Locomotion distance, session 10.10.21.0-0.50.40.7-0.21.00.8-0.0-0.80.1-0.10.10.20.20.1-0.10.10.0-0.40.3-0.3-0.30.3-0.30.3
Locomotion velocity, session 23.03.55.5-2.42.01.7-1.81.91.8-2.0-2.02.0-1.9-2.01.81.9-2.12.1-1.82.01.9-1.81.81.6-1.61.6-1.6
Locomotion distance, session 20.40.61.8-1.31.21.2-0.81.31.0-0.8-1.10.8-0.7-0.60.60.6-0.60.6-0.50.4-0.0-0.10.10.1-0.10.0-0.1
Locomotion velocity, session 30.10.10.6-0.00.10.30.10.80.70.2-0.5-0.10.20.4-0.1-0.00.4-0.40.30.1-0.40.5-0.4-0.40.4-0.30.4
Locomotion distance, session 33.03.45.9-1.51.92.2-1.92.42.4-1.7-2.31.8-1.8-1.52.02.0-1.51.5-1.81.91.6-1.61.61.7-1.71.8-1.7
Stereotopy head waving bouts, day 30.91.12.01.1-0.6-0.30.7-0.3-0.31.00.6-1.01.01.2-0.9-1.01.4-1.41.0-1.0-1.41.3-1.2-1.21.2-1.11.2
Stereotopy head waving duration, day 30.81.01.90.9-0.8-0.60.8-0.4-0.41.00.7-1.01.01.1-0.9-1.01.4-1.41.0-0.9-1.31.3-1.0-1.11.1-1.11.1
Locomotion velocity, session 70.10.10.2-0.4-0.2-0.30.40.30.00.2-0.1-0.10.20.1-0.2-0.10.2-0.20.3-0.1-0.20.3-0.3-0.30.4-0.30.3
Locomotion distance, session 70.20.30.9-0.90.60.6-0.41.00.9-0.4-0.80.6-0.5-0.40.50.6-0.50.5-0.40.60.5-0.40.30.3-0.20.3-0.3
Stereotopy head waving bouts, day 71.41.63.0-0.61.41.6-1.51.71.7-1.2-1.61.2-1.2-1.01.41.4-0.80.8-1.31.30.9-1.01.21.1-1.21.3-1.1
Stereotopy head waving duration, day 70.20.30.8-0.00.70.9-0.80.80.8-0.6-0.70.5-0.5-0.40.60.5-0.20.2-0.60.50.3-0.20.50.4-0.50.5-0.4
Locomotion velocity, session 80.80.91.90.5-0.5-0.40.7-0.2-0.40.80.3-0.90.91.0-1.0-1.01.0-1.01.1-0.9-1.31.4-1.3-1.21.3-1.31.2
Locomotion distance, session 80.10.10.4-0.50.20.30.10.60.40.1-0.3-0.00.10.2-0.1-0.10.3-0.30.2-0.1-0.50.5-0.5-0.40.5-0.50.4
Degree of sensitization distance2.12.33.00.7-1.4-1.61.6-1.6-1.71.41.6-1.41.51.2-1.6-1.61.3-1.31.6-1.5-1.41.4-1.5-1.61.7-1.71.6
Degree of sensitization stereotypy2.42.63.6-1.01.61.7-1.71.91.8-1.6-1.91.6-1.6-1.41.81.8-1.41.4-1.71.71.5-1.51.61.6-1.71.8-1.6
Conditioned locomotion0.10.10.60.10.10.5-0.20.80.80.0-0.70.1-0.10.20.30.3-0.00.0-0.10.20.1-0.00.0-0.00.00.20.0
Cocaine response after cond. corrected1.42.23.01.5-1.4-1.11.5-0.8-0.91.71.0-1.51.51.7-1.4-1.41.7-1.71.6-1.4-1.61.7-1.6-1.51.5-1.41.5
Cocaine response after cond. not corrected2.23.14.41.5-1.5-1.21.7-1.0-1.21.91.4-1.81.82.0-1.7-1.82.0-2.01.9-1.8-2.02.1-2.0-1.91.9-1.91.9
Cocaine response before conditioning0.10.10.7-0.80.60.4-0.40.20.2-0.5-0.20.4-0.4-0.50.20.2-0.30.3-0.30.10.2-0.30.20.1-0.20.0-0.2
Saline control response0.10.20.7-0.40.70.9-0.60.70.7-0.4-0.60.4-0.4-0.20.40.3-0.20.2-0.30.20.3-0.10.10.1-0.00.1-0.1
Bone: connectivity density1.62.55.7-2.41.61.2-1.31.31.1-1.6-1.31.8-1.7-1.81.61.5-1.61.6-1.61.41.5-1.61.51.6-1.71.5-1.6
Bone: cortical apparent density0.10.10.5-0.70.1-0.2-0.10.0-0.1-0.3-0.10.4-0.3-0.60.20.3-0.60.6-0.30.50.4-0.40.40.4-0.40.3-0.5
Bone: cortical area2.64.27.5-2.72.11.6-1.91.41.4-2.2-1.52.2-2.2-2.41.91.9-2.32.3-2.02.02.1-2.12.12.1-2.01.9-2.1
Bone: cortical porosity0.10.20.20.3-0.4-0.40.4-0.4-0.40.40.4-0.40.40.3-0.4-0.40.4-0.40.4-0.5-0.40.4-0.4-0.30.3-0.40.3
Bone: cortical porosity0.00.00.10.00.10.2-0.20.20.3-0.1-0.20.1-0.1-0.10.20.2-0.00.0-0.20.10.1-0.10.20.2-0.20.2-0.3
Bone: cortical thickness1.83.05.8-2.41.51.0-1.31.21.0-1.7-1.31.9-1.8-2.11.61.7-1.91.9-1.61.81.8-1.81.82.0-1.91.7-2.0
Bone: cortical thickness0.10.20.6-0.2-0.5-0.70.6-0.6-0.80.30.5-0.30.30.1-0.4-0.40.0-0.00.4-0.3-0.10.2-0.3-0.20.2-0.30.2
Bone: cortical tissue density0.10.10.3-0.50.0-0.30.0-0.0-0.1-0.2-0.10.2-0.2-0.50.10.2-0.40.4-0.20.40.3-0.20.20.3-0.30.2-0.3
Condit. Reinf. active minus inactive responses0.30.30.5-0.60.70.6-0.60.30.3-0.6-0.40.6-0.6-0.60.50.4-0.70.7-0.50.50.6-0.40.50.6-0.50.4-0.6
Condit. Reinf. active-inactive response ratio0.70.81.61.2-1.0-0.90.8-1.3-1.20.81.1-0.90.90.8-0.9-0.90.7-0.70.8-0.9-0.60.8-0.7-0.60.6-0.60.6
Condit. Reinf. active responses2.12.74.0-2.01.91.7-1.81.41.5-1.8-1.51.7-1.7-1.81.51.5-1.81.8-1.51.61.6-1.41.51.6-1.51.3-1.6
Condit. Reinf. inactive responses2.53.27.0-2.62.11.7-1.81.61.6-2.0-1.72.0-1.9-2.11.61.6-1.91.9-1.81.71.6-1.61.71.5-1.71.3-1.5
Incentive salience index mean3.14.05.7-2.12.42.3-2.31.81.9-2.2-2.02.1-2.1-2.02.01.9-2.12.1-2.01.91.9-1.71.81.9-1.81.7-1.9
Condit. Reinf. lever presses7.210.815.5-3.43.93.9-3.73.43.5-3.5-3.53.4-3.4-3.23.43.3-3.13.1-3.33.02.9-2.82.92.9-2.92.8-2.9
Condit. Reinf. active minus inactive responses0.81.21.8-1.31.00.9-1.00.90.9-1.1-0.91.2-1.1-1.21.11.1-1.21.2-1.11.11.3-1.21.11.1-1.11.1-1.1
Condit. Reinf. active-inactive response ratio0.40.61.0-0.50.50.4-0.60.40.5-0.7-0.60.7-0.7-0.80.70.8-0.90.9-0.80.81.0-0.90.90.9-0.91.0-0.9
Condit. Reinf. active responses2.02.94.7-2.21.91.6-1.71.51.4-1.8-1.51.8-1.8-1.81.71.6-1.81.8-1.71.51.8-1.71.61.6-1.61.5-1.6
Condit. Reinf. inactive responses1.82.75.8-2.41.91.6-1.61.31.2-1.8-1.31.8-1.8-1.91.61.5-1.71.7-1.61.41.6-1.61.51.5-1.51.3-1.5
Condit. Reinf. lever presses2.53.66.7-2.62.01.5-1.81.31.3-2.1-1.42.1-2.0-2.31.71.7-2.22.2-2.01.82.1-2.01.91.8-1.81.6-1.8
Condit. Reinf. lever reinforcers received2.23.05.2-2.32.01.7-1.81.51.4-1.9-1.51.9-1.9-1.91.71.7-1.91.9-1.81.51.8-1.71.61.6-1.61.5-1.6
Conditioned reinforcement - actives0.10.40.8-0.10.50.6-0.50.90.9-0.4-0.90.5-0.5-0.40.70.7-0.80.8-0.60.60.6-0.50.60.8-0.70.7-0.8
Conditioned reinforcement - inactives0.00.10.20.2-0.4-0.30.50.30.10.5-0.1-0.30.40.4-0.2-0.10.4-0.40.3-0.3-0.20.2-0.4-0.20.3-0.30.2
Conditioned locomotion0.50.81.8-0.50.60.9-0.71.31.2-0.6-1.30.8-0.8-0.61.11.1-0.80.8-0.90.91.0-1.00.80.8-0.71.1-0.8
Patch foraging indifference point 0 sec0.41.24.9-0.41.11.7-1.12.22.0-0.7-1.90.9-0.9-0.41.31.3-0.20.2-0.91.10.5-0.60.60.6-0.41.0-0.6
Patch foraging indifference point AUC3.99.212.4-3.13.53.5-3.43.13.1-3.2-3.23.2-3.1-3.03.13.0-3.33.3-2.92.73.0-2.82.72.6-2.62.6-2.6
Delay disc. indifference point, 0s delay1.41.62.11.3-1.2-1.11.2-0.8-0.91.41.0-1.31.31.4-1.3-1.21.4-1.41.4-1.2-1.41.3-1.4-1.31.4-1.31.3
Delay disc. indifference point, 16s delay0.91.32.51.4-1.1-0.71.1-0.5-0.61.30.7-1.21.21.4-1.0-1.11.0-1.01.2-1.3-1.11.2-1.3-1.61.3-1.11.5
Delay disc. indifference point, 2s delay0.20.20.6-0.80.30.1-0.20.40.5-0.4-0.50.5-0.4-0.50.30.4-0.40.4-0.40.70.4-0.40.40.6-0.50.3-0.5
Delay disc. indifference point, 24s delay0.20.30.40.5-0.5-0.50.5-0.6-0.60.50.6-0.50.50.5-0.6-0.60.2-0.20.5-0.5-0.40.6-0.4-0.50.6-0.60.4
Delay disc. indifference point, 4s delay0.10.10.3-0.4-0.2-0.20.40.10.00.30.0-0.20.30.2-0.3-0.3-0.00.00.4-0.3-0.30.3-0.5-0.40.5-0.60.4
Delay disc. indifference point, 8s delay0.00.00.30.6-0.1-0.1-0.0-0.2-0.10.10.0-0.20.20.2-0.2-0.1-0.30.30.2-0.2-0.10.1-0.3-0.20.3-0.30.2
Indifference point function ln k1.13.34.61.8-2.0-1.92.0-1.6-1.62.01.8-1.91.91.8-1.8-1.82.1-2.11.8-1.6-1.91.8-1.7-1.61.7-1.61.6
Indifference point function log k1.13.34.61.8-2.0-1.92.0-1.6-1.62.01.8-1.91.91.8-1.8-1.82.1-2.11.8-1.6-1.91.8-1.7-1.61.7-1.61.6
Patch foraging total patch changes 0 sec0.72.16.7-0.61.52.1-1.52.62.4-1.1-2.31.3-1.3-0.81.71.7-0.60.6-1.41.60.9-1.01.11.0-0.91.5-1.1
Patch foraging total patch changes 12 sec3.74.96.3-1.92.22.3-2.32.52.4-2.2-2.52.2-2.3-2.12.42.4-2.02.0-2.32.22.2-2.12.22.1-2.12.3-2.0
Patch foraging total patch changes 18 sec0.30.81.3-1.11.11.1-1.01.10.9-0.9-1.00.9-0.9-0.90.90.9-0.80.8-0.80.70.8-0.80.80.6-0.50.7-0.6
Patch foraging total patch changes 24 sec1.34.47.7-1.72.22.4-2.22.82.5-2.0-2.72.1-2.1-1.82.22.3-1.91.9-1.92.01.9-1.91.91.8-1.72.0-1.8
Patch foraging total patch changes 6 sec2.94.98.4-1.82.52.9-2.52.82.7-2.1-2.72.3-2.3-1.92.52.4-1.81.8-2.12.12.0-1.91.91.8-1.72.2-1.8
Patch foraging time to switch 0 sec1.14.16.51.8-2.3-2.62.3-2.2-2.32.12.2-2.12.11.8-2.2-2.11.9-1.92.0-1.9-2.01.9-1.7-1.81.7-1.91.7
Patch foraging water rate 0 sec1.45.28.0-1.92.32.7-2.32.82.8-2.1-2.72.3-2.3-1.92.62.5-1.81.8-2.22.32.3-2.22.12.1-2.02.4-2.1
Patch foraging water rate 12 sec0.00.10.5-0.10.20.3-0.10.70.5-0.0-0.50.1-0.10.00.20.30.2-0.2-0.00.20.2-0.1-0.1-0.0-0.00.10.0
Patch foraging water rate 18 sec1.02.23.1-1.41.11.1-1.21.21.3-1.3-1.31.5-1.5-1.41.51.6-1.31.3-1.51.51.8-1.71.51.8-1.71.8-1.7
Patch foraging water rate 24 sec0.40.61.2-0.90.30.1-0.30.10.3-0.6-0.30.7-0.7-0.80.70.7-1.11.1-0.70.71.1-1.10.81.1-1.00.9-1.1
Patch foraging water rate 6 sec0.50.71.5-1.20.90.9-0.71.10.9-0.7-0.90.8-0.8-0.80.90.8-0.70.7-0.80.80.7-0.60.60.9-0.80.7-0.9
Seeking ratio, delayed vs. immediate footshock4.26.06.9-2.22.52.5-2.52.52.6-2.5-2.62.5-2.5-2.52.52.6-2.42.4-2.52.62.4-2.52.32.3-2.12.4-2.4
Distance traveled before self-admin1.02.14.7-1.61.81.9-1.62.22.2-1.5-2.01.4-1.4-1.21.51.4-1.21.2-1.21.41.0-1.00.91.1-0.81.0-1.0
Distance traveled after self-admin0.40.72.3-1.50.90.5-0.70.70.6-0.9-0.70.9-0.8-1.00.60.8-1.11.1-0.70.80.9-0.70.71.0-0.70.4-0.9
Extensor digitorum longus weight4.417.822.6-4.24.74.7-4.64.14.3-4.4-4.34.4-4.4-4.24.44.2-4.24.2-4.24.13.9-3.93.93.9-3.83.9-3.9
Bone: elastic displacement2.02.55.11.5-2.2-2.32.1-1.5-1.71.81.5-1.71.71.5-1.6-1.41.6-1.61.6-1.4-1.21.1-1.2-1.11.2-1.21.2
Bone: elastic work0.30.42.40.1-1.1-1.51.0-1.0-1.00.50.9-0.40.40.0-0.6-0.30.1-0.10.4-0.10.3-0.20.10.1-0.10.0-0.2
Bone: endosteal estimation0.30.81.8-1.01.31.3-1.20.71.0-1.0-0.70.9-0.9-0.80.90.7-0.90.9-0.80.70.8-0.80.70.5-0.50.6-0.4
Bone: endosteal perimeter0.41.02.3-0.71.41.5-1.30.91.1-1.1-0.91.0-1.0-0.81.10.9-1.01.0-1.00.81.0-0.90.80.7-0.70.8-0.6
Epididymis fat weight0.10.61.1-0.70.90.8-0.90.50.5-1.0-0.60.8-0.8-0.80.70.6-1.01.0-0.80.70.8-0.80.70.3-0.60.6-0.4
Delta time in closed arm before/after self-admin0.60.61.3-1.00.70.4-0.60.10.3-0.8-0.30.8-0.8-1.00.60.7-0.70.7-0.70.80.9-0.80.91.1-0.90.7-1.1
Delta time in open arm before/after self-admin0.40.41.00.7-0.5-0.30.60.0-0.10.70.2-0.60.70.8-0.6-0.50.7-0.70.7-0.6-0.60.7-0.9-0.90.9-0.81.0
Diff in mean of infusions in LGA sessions0.20.31.6-0.3-0.4-0.70.6-1.3-1.10.41.0-0.30.40.2-0.6-0.70.2-0.20.4-0.8-0.30.2-0.4-0.40.2-0.60.3
Delay discount exponential model param0.40.50.9-0.90.70.5-0.70.30.3-0.8-0.30.8-0.8-0.90.70.7-0.50.5-0.90.70.7-0.81.00.9-0.90.9-0.9
Extinction: sum of active levers before priming3.14.76.82.6-2.2-2.02.1-2.1-2.02.32.0-2.32.32.3-2.2-2.12.0-2.02.2-2.2-2.22.2-2.3-1.92.2-2.21.8
Active lever presses in extinction session 60.10.10.30.5-0.4-0.20.3-0.3-0.50.40.3-0.30.30.4-0.2-0.20.2-0.20.2-0.5-0.20.3-0.3-0.30.3-0.20.2
Bone: final force0.60.92.4-1.61.31.0-1.10.60.5-1.2-0.61.1-1.1-1.20.80.7-1.11.1-0.90.80.8-0.70.60.9-0.90.6-0.9
Bone: final moment0.40.72.0-1.41.10.8-0.90.40.4-1.0-0.41.0-1.0-1.10.70.6-1.01.0-0.80.70.7-0.60.60.8-0.80.6-0.8
Food consumed during 24 hour testing period0.10.20.6-0.70.70.7-0.50.50.5-0.5-0.50.5-0.4-0.40.40.3-0.50.5-0.40.20.2-0.30.20.1-0.10.1-0.1
Glucose2.53.95.1-1.52.22.3-2.31.82.1-2.1-2.02.0-2.0-1.92.11.9-1.91.9-2.11.92.1-1.91.91.8-1.82.0-1.8
Heart weight0.20.40.8-0.40.90.8-0.90.40.5-0.8-0.50.6-0.7-0.70.60.4-0.70.7-0.60.50.4-0.40.50.6-0.50.4-0.5
Delay discount hyperbolic model param0.30.30.7-0.60.50.4-0.60.10.1-0.6-0.10.6-0.6-0.70.60.5-0.30.3-0.70.50.5-0.60.80.7-0.80.7-0.7
Intermittent access intake day 1-15 change0.31.73.1-1.71.21.0-1.11.41.3-1.3-1.31.3-1.3-1.41.21.4-1.11.1-1.31.31.3-1.21.41.5-1.51.2-1.5
Intermittent access intake escalation0.31.43.1-1.81.00.8-0.91.31.1-1.1-1.21.2-1.2-1.31.11.2-1.11.1-1.11.21.2-1.11.21.4-1.41.0-1.4
Intermittent access intake escalation 21.52.55.2-2.31.40.9-1.21.01.0-1.6-1.11.7-1.6-1.91.41.5-1.71.7-1.61.61.7-1.71.81.8-1.91.5-1.8
Intermitt. access day 1 inactive lever presses0.10.91.4-1.01.21.2-1.10.90.8-1.0-0.91.0-1.0-0.91.00.9-0.90.9-0.90.61.0-1.00.80.7-0.80.8-0.7
Intermitt. access day 15 inactive lever presses0.00.00.20.00.20.3-0.10.50.4-0.0-0.30.00.00.10.00.1-0.20.20.1-0.2-0.1-0.0-0.3-0.30.2-0.20.3
Intermitt. access escalation Index0.10.20.3-0.50.50.5-0.40.50.6-0.4-0.40.4-0.4-0.30.30.50.3-0.3-0.30.4-0.20.00.30.5-0.40.3-0.5
Intermittent access day 1 total infusions0.20.73.41.8-0.9-0.30.60.30.11.00.0-0.90.81.2-0.5-0.41.0-1.00.7-0.6-0.70.7-0.7-0.90.8-0.31.0
Intermittent access day 15 total infusions0.40.91.8-0.50.60.7-0.71.41.2-0.7-1.20.9-0.9-0.81.01.2-0.70.7-1.01.01.0-1.01.01.0-1.11.1-1.0
Intermittent access terminal intake (last 3 days)0.61.11.8-0.50.70.9-0.81.31.3-0.8-1.31.0-0.9-0.81.11.3-0.70.7-1.11.11.1-1.11.11.2-1.21.2-1.2
Intermittent access total infusions0.81.02.5-0.20.71.0-0.91.61.5-0.7-1.40.8-0.8-0.61.11.2-0.60.6-0.91.01.0-1.00.90.8-1.01.2-0.8
Intermittent access day 1 locomotion0.20.42.91.7-0.8-0.30.50.40.30.7-0.3-0.70.60.9-0.3-0.20.5-0.50.5-0.2-0.20.2-0.5-0.80.5-0.10.8
Intermittent access day 15 total locomotion0.10.21.41.2-0.6-0.20.40.70.30.5-0.4-0.40.40.7-0.00.10.5-0.50.2-0.3-0.00.0-0.2-0.40.30.10.4
Intermittent access total locomotion0.10.10.90.9-0.7-0.50.50.30.20.5-0.2-0.30.40.5-0.10.10.2-0.20.2-0.10.2-0.2-0.1-0.30.10.10.3
Intermittent access standard deviation0.21.01.4-0.80.91.0-0.91.21.1-0.9-1.11.0-1.0-0.91.11.1-0.80.8-1.01.00.9-0.90.91.1-1.11.0-1.1
Left kidney weight0.10.51.7-0.61.11.3-1.01.01.0-0.7-1.00.6-0.7-0.40.70.6-0.60.6-0.60.50.3-0.30.20.3-0.10.2-0.2
Right kidney weight0.10.41.3-0.10.90.8-1.00.20.5-0.8-0.60.6-0.6-0.60.50.4-1.11.1-0.70.60.6-0.50.50.4-0.40.4-0.3
Cocaine induced anxiety0.10.40.60.1-0.6-0.60.7-0.4-0.40.60.5-0.60.60.6-0.6-0.60.7-0.70.7-0.5-0.40.5-0.7-0.70.8-0.70.7
Post-drug Anxiety0.10.10.5-0.30.30.3-0.10.20.2-0.0-0.1-0.10.10.1-0.2-0.30.3-0.30.2-0.2-0.30.4-0.4-0.60.7-0.50.6
Baseline Anxiety0.10.20.6-0.40.70.5-0.6-0.1-0.0-0.6-0.00.4-0.5-0.50.30.1-0.80.8-0.50.10.2-0.00.40.2-0.20.1-0.2
Tail length0.52.94.9-1.52.22.1-2.11.61.6-2.0-1.61.7-1.8-1.71.71.6-2.12.1-1.71.41.6-1.51.51.1-1.41.3-1.1
Length with tail0.62.76.2-1.32.22.5-2.22.12.0-1.8-1.91.6-1.7-1.31.81.6-1.61.6-1.71.21.4-1.21.20.8-1.11.3-0.8
Length without tail0.00.10.40.30.20.6-0.20.60.60.1-0.4-0.10.10.40.20.00.2-0.20.0-0.2-0.20.3-0.3-0.40.3-0.10.4
Times rat made contact with spout0.80.91.3-0.70.80.7-0.90.81.0-0.9-0.90.9-0.9-1.00.91.0-1.01.0-1.01.20.9-1.01.00.9-0.91.1-0.9
Lifetime Intake0.50.72.40.20.50.9-0.71.51.5-0.4-1.40.6-0.6-0.30.91.0-0.40.4-0.70.80.7-0.70.70.6-0.71.0-0.6
Liver weight, left0.30.61.00.8-0.5-0.50.5-0.8-0.80.60.8-0.70.70.7-0.7-0.90.7-0.70.6-0.8-1.00.8-0.7-0.80.8-0.80.8
Liver weight, right0.61.11.71.2-1.2-1.21.1-1.3-1.31.11.2-1.11.11.0-1.0-1.00.8-0.81.0-1.2-0.70.8-0.9-1.00.9-0.91.0
Locomotor activity0.10.10.4-0.1-0.1-0.10.2-0.7-0.60.20.5-0.20.20.2-0.2-0.40.0-0.00.1-0.4-0.20.1-0.3-0.30.2-0.40.3
Locomotor testing distance0.40.91.40.5-0.7-0.50.9-0.8-0.80.90.8-0.90.91.0-0.9-1.01.0-1.00.9-1.1-1.10.9-1.2-1.11.1-1.11.1
Locomotor testing rearing0.00.11.1-1.10.60.5-0.3-0.00.2-0.3-0.10.4-0.3-0.30.20.1-0.20.2-0.2-0.00.1-0.3-0.20.1-0.1-0.2-0.1
Locomotion in novel chamber0.10.10.3-0.2-0.3-0.50.2-0.5-0.5-0.00.30.1-0.1-0.3-0.00.2-0.30.3-0.20.20.2-0.40.40.5-0.30.3-0.5
Locomotion in novel chamber post-restriction0.72.24.3-2.11.40.9-1.21.11.0-1.6-1.21.6-1.5-1.81.21.5-1.61.6-1.41.71.5-1.41.61.7-1.61.3-1.7
Fecal boli incidents, locomotor time 10.20.51.30.6-0.8-1.00.8-1.1-1.10.71.0-0.70.70.5-0.8-0.70.5-0.50.6-0.9-0.40.4-0.4-0.60.6-0.70.6
Change in fecal boli incidents, locomotor task0.60.62.20.20.61.0-0.91.31.5-0.7-1.20.5-0.6-0.30.90.8-0.70.7-0.71.00.6-0.70.50.4-0.40.9-0.4
Time >=10cm from walls, locomotor time 10.10.10.50.50.00.4-0.20.70.60.1-0.6-0.10.10.30.10.20.5-0.50.00.1-0.40.1-0.30.00.20.1-0.0
Bouts of movement, locomotor time 11.72.23.71.2-1.5-1.61.6-1.7-1.91.51.7-1.41.51.3-1.5-1.61.3-1.31.5-1.8-1.51.3-1.3-1.31.7-1.41.3
Total resting periods, locomotor time 12.12.44.61.2-1.7-1.81.7-2.0-2.11.51.9-1.51.51.3-1.6-1.61.3-1.31.5-1.8-1.41.2-1.4-1.31.6-1.51.3
Rest time, locomotor task time 10.81.25.1-0.1-1.2-1.81.3-2.1-2.30.81.9-0.80.90.4-1.2-1.10.3-0.30.8-1.2-0.50.4-0.7-0.50.6-1.00.5
Distance moved, locomotor task time 10.51.54.6-0.31.41.9-1.52.12.1-1.0-1.81.0-1.1-0.71.41.4-0.60.6-1.11.30.8-0.70.60.8-1.01.2-0.8
Vertical activity count, locomotor time 10.00.31.60.40.61.2-0.71.21.3-0.2-0.80.2-0.20.20.50.30.6-0.6-0.20.4-0.50.5-0.10.1-0.20.3-0.1
Time >=10cm from walls, locomotor time 20.00.10.40.60.10.3-0.30.50.7-0.1-0.5-0.10.00.10.00.10.1-0.1-0.00.2-0.10.3-0.2-0.10.1-0.00.1
Bouts of movement, locomotor time 20.10.41.2-1.10.80.7-0.70.10.3-0.7-0.20.8-0.7-0.80.60.3-0.90.9-0.80.40.5-0.30.60.8-0.20.5-0.8
Total resting periods, locomotor time 20.10.20.8-0.90.50.4-0.4-0.2-0.1-0.40.00.5-0.5-0.60.40.2-0.60.6-0.60.20.3-0.20.40.7-0.10.3-0.7
Rest time, locomotor task time 20.40.71.90.6-1.0-1.11.0-1.2-1.40.91.2-0.80.80.7-0.8-0.80.7-0.70.7-1.0-0.50.5-0.6-0.40.5-0.60.4
Distance moved, locomotor task time 20.10.20.3-0.50.60.3-0.50.10.3-0.6-0.20.4-0.5-0.60.30.2-0.50.5-0.40.40.4-0.20.20.3-0.50.2-0.3
Vertical activity count, locomotor time 20.00.10.3-0.20.40.4-0.30.40.5-0.2-0.30.1-0.2-0.10.10.00.2-0.2-0.00.3-0.50.4-0.10.1-0.1-0.1-0.1
Light reinforcement 10.10.61.50.50.30.8-0.10.70.50.4-0.4-0.40.40.9-0.2-0.40.7-0.70.5-0.9-1.01.0-1.1-1.11.2-0.91.1
Light reinforcement 20.40.92.41.0-0.10.50.20.10.10.80.2-0.80.81.2-0.5-0.81.3-1.30.7-1.2-1.61.5-1.2-1.21.2-1.01.2
Bone: marrow area0.41.01.9-1.21.41.4-1.30.71.0-1.2-0.71.1-1.1-1.01.00.8-1.01.0-0.90.80.9-0.90.80.6-0.70.7-0.6
Bone: maximum diameter1.93.74.7-2.12.21.9-2.11.41.5-2.2-1.62.1-2.1-2.11.91.8-2.12.1-1.91.81.9-1.91.91.9-1.91.8-1.9
Bone: maximum force1.63.15.2-2.32.11.8-1.91.21.2-2.0-1.21.9-1.9-2.11.71.5-2.12.1-1.71.61.7-1.51.51.7-1.71.5-1.7
Bone: maximum moment1.32.54.4-2.11.91.5-1.70.91.0-1.8-1.01.8-1.8-1.91.51.4-1.91.9-1.61.41.5-1.41.41.6-1.51.3-1.6
Mean time between licks in bursts0.53.14.91.1-1.4-1.71.6-2.0-2.21.52.0-1.61.61.4-1.9-2.01.6-1.61.7-1.9-1.81.9-1.7-1.71.7-2.01.7
Mean num. licks in bursts0.92.52.91.4-1.7-1.71.7-1.5-1.51.61.6-1.61.61.5-1.6-1.71.4-1.41.6-1.4-1.51.5-1.5-1.71.7-1.51.7
Cd content in liver0.20.20.6-0.00.50.6-0.60.60.8-0.5-0.70.3-0.4-0.30.40.4-0.40.4-0.40.60.2-0.30.30.3-0.30.3-0.3
Co content in liver1.31.52.31.0-1.1-0.91.1-0.8-1.01.31.0-1.21.21.3-1.2-1.21.5-1.51.3-1.4-1.41.3-1.4-1.31.3-1.31.3
Cu content in liver2.83.44.32.0-1.9-2.01.8-2.0-2.11.82.0-1.91.91.8-2.0-1.91.7-1.71.9-1.7-1.71.6-1.8-1.71.7-1.81.7
Fe content in liver2.73.44.82.1-1.7-1.41.7-1.3-1.41.91.4-2.02.02.1-1.9-1.91.4-1.42.0-1.9-1.72.1-2.2-2.12.1-2.02.1
K content in liver0.40.40.80.3-0.5-0.40.6-0.2-0.20.70.5-0.60.60.7-0.6-0.70.8-0.80.7-0.6-0.90.8-0.8-0.70.7-0.70.7
Mg content in liver0.30.30.80.8-0.7-0.50.5-0.6-0.40.60.6-0.50.50.6-0.4-0.50.9-0.90.4-0.4-0.60.5-0.3-0.30.3-0.20.3
Mn content in liver1.31.53.2-1.81.30.9-1.10.70.7-1.3-0.81.4-1.3-1.51.11.1-1.31.3-1.31.11.1-1.21.31.3-1.31.1-1.3
Na content in liver4.55.06.42.0-2.1-2.22.2-2.5-2.52.12.5-2.32.22.1-2.4-2.42.1-2.12.2-2.4-1.92.2-2.2-2.22.2-2.42.2
Rb content in liver6.17.18.52.1-2.9-2.82.9-2.6-2.82.82.8-2.72.72.6-2.7-2.72.7-2.72.7-2.8-2.82.6-2.5-2.52.5-2.52.5
Se content in liver1.72.02.9-1.51.71.3-1.51.21.2-1.6-1.31.5-1.5-1.61.31.4-1.71.7-1.41.31.5-1.31.31.3-1.31.1-1.3
Sr content in liver0.20.20.5-0.40.70.7-0.70.20.3-0.6-0.40.5-0.5-0.50.40.4-0.30.3-0.50.20.3-0.30.30.3-0.30.2-0.3
Zn content in liver0.00.00.10.3-0.1-0.2-0.0-0.3-0.2-0.00.1-0.10.10.0-0.2-0.1-0.20.20.10.0-0.00.1-0.0-0.00.0-0.10.0
Bone: minimum diameter0.00.10.9-1.00.1-0.10.1-0.2-0.3-0.20.30.3-0.2-0.40.10.0-0.40.4-0.1-0.00.4-0.30.20.0-0.10.0-0.1
Time in familiar zone, hab. session 10.60.61.5-0.50.1-0.3-0.3-0.10.0-0.6-0.10.7-0.7-1.00.60.7-0.90.9-0.80.91.1-1.21.11.1-1.11.1-1.1
Time in novel zone, hab. session 15.96.69.12.3-2.0-1.72.2-1.7-1.92.52.0-2.62.62.8-2.5-2.62.7-2.72.7-2.8-2.93.0-2.9-2.92.9-3.02.9
Total zone transitions, hab. session 10.00.00.2-0.50.1-0.10.2-0.1-0.30.10.1-0.00.1-0.0-0.2-0.20.1-0.10.2-0.3-0.40.4-0.2-0.10.1-0.30.1
Total locomotion distance, hab. session 10.40.63.9-2.00.90.3-0.50.40.2-0.9-0.31.0-0.9-1.20.50.6-0.80.8-0.70.60.4-0.60.70.8-0.80.4-0.8
Locomotion velocity, hab. session 11.52.17.6-2.71.71.2-1.31.00.8-1.6-1.01.7-1.6-1.91.31.2-1.51.5-1.41.21.0-1.21.41.4-1.51.0-1.4
Time in familiar zone, hab. session 20.20.21.1-0.0-0.6-1.00.6-1.0-1.00.30.9-0.30.30.0-0.5-0.40.2-0.20.3-0.4-0.10.0-0.1-0.10.1-0.20.1
Time in novel zone, hab. session 21.82.03.11.8-1.3-0.91.3-0.6-0.61.50.8-1.51.51.8-1.3-1.31.6-1.61.5-1.3-1.61.6-1.6-1.61.6-1.41.6
Total zone transitions, hab. session 20.20.31.3-0.80.70.8-0.51.10.8-0.4-1.00.5-0.4-0.30.40.5-0.30.3-0.30.4-0.0-0.00.10.2-0.20.1-0.2
Total locomotion distance, hab. session 20.81.03.9-2.01.21.0-0.81.30.9-1.0-1.21.1-1.1-1.10.91.0-0.90.9-0.80.90.6-0.70.70.8-0.80.6-0.8
Locomotion velocity, hab. session 21.11.54.3-2.11.41.2-1.11.51.1-1.2-1.31.4-1.3-1.41.11.2-1.11.1-1.11.20.8-0.91.01.1-1.10.9-1.1
Novel to familiar place preference ratio3.34.35.31.9-2.0-1.72.1-1.5-1.82.21.7-2.12.12.3-2.0-2.02.3-2.32.1-2.1-2.22.2-2.2-2.22.3-2.02.2
Novelty place preference4.15.26.22.2-2.3-2.02.3-1.7-2.02.52.0-2.42.42.5-2.2-2.22.5-2.52.4-2.3-2.32.3-2.3-2.32.4-2.22.3
Time in novel zone, NPP test5.76.98.02.5-2.6-2.32.7-2.1-2.32.82.3-2.72.72.8-2.5-2.62.8-2.82.7-2.7-2.72.7-2.7-2.72.8-2.52.7
Total zone transitions, NPP test0.10.21.2-0.70.70.8-0.51.10.6-0.4-0.90.4-0.3-0.20.30.3-0.20.2-0.20.2-0.20.1-0.1-0.10.1-0.10.1
Total locomotion distance, NPP test1.62.24.6-2.11.81.9-1.52.11.8-1.5-1.91.6-1.5-1.41.51.5-1.21.2-1.31.41.0-1.11.01.1-1.11.1-1.1
Locomotion velocity, NPP test2.53.66.1-2.52.22.2-1.92.52.1-1.9-2.32.0-1.9-1.82.02.0-1.71.7-1.71.91.4-1.61.51.6-1.61.5-1.6
Intraocular pressure2.44.06.3-1.62.12.4-2.22.42.5-2.0-2.52.0-2.0-1.72.22.1-1.71.7-1.91.91.9-2.01.81.6-1.72.0-1.6
Delta distance traveled before/after self-admin0.20.20.8-0.2-0.5-0.80.6-0.8-0.90.40.8-0.40.40.2-0.6-0.50.2-0.20.4-0.5-0.40.5-0.3-0.20.2-0.60.2
Delta ambulatory time before/after self-admin0.71.22.70.6-1.1-1.41.2-1.6-1.61.01.5-1.01.10.8-1.2-1.20.8-0.81.0-1.1-0.91.1-0.9-0.80.8-1.10.9
Parametrial fat weight0.61.42.30.8-0.8-0.71.0-1.0-1.11.11.1-1.11.11.2-1.1-1.41.0-1.01.1-1.5-1.31.4-1.3-1.41.4-1.41.4
Pavlov. Cond. lever latency5.36.89.22.6-3.0-3.02.9-2.5-2.62.82.6-2.72.72.6-2.7-2.62.6-2.62.6-2.4-2.42.3-2.4-2.52.4-2.32.5
Pavlov. Cond. magazine entry latency0.10.20.5-0.50.60.5-0.6-0.0-0.0-0.6-0.10.5-0.5-0.50.30.3-0.70.7-0.40.00.5-0.40.40.3-0.30.2-0.3
Pavlov. Cond. change in total contacts2.12.33.1-1.41.71.8-1.71.61.5-1.6-1.71.5-1.6-1.41.61.5-1.61.6-1.51.31.5-1.41.41.3-1.31.3-1.3
Pavlov. Cond. index score2.02.53.7-1.61.91.7-1.81.21.3-1.8-1.41.7-1.7-1.71.51.5-1.81.8-1.61.31.6-1.51.51.5-1.51.3-1.5
Pavlov. Cond. latency score1.92.53.6-1.51.91.8-1.81.11.3-1.8-1.31.7-1.7-1.71.61.5-1.81.8-1.61.31.6-1.51.51.6-1.51.4-1.6
Pavlov. Cond. lever contacts5.56.68.7-2.72.92.8-2.82.32.4-2.7-2.52.7-2.7-2.62.62.5-2.62.6-2.62.32.4-2.32.42.5-2.42.3-2.5
Pavlov. Cond. magazine entry number0.40.61.10.5-0.8-0.70.9-0.2-0.30.90.4-0.70.80.8-0.7-0.61.0-1.00.8-0.4-0.90.8-0.8-0.80.7-0.70.8
Pavlov. Cond. intertrial magazine entries0.10.20.7-0.80.60.4-0.40.40.4-0.5-0.40.5-0.4-0.50.40.3-0.40.4-0.30.40.3-0.20.30.3-0.30.2-0.3
Pavlov. Cond. lever-magazine prob. diff.2.22.83.8-1.82.01.7-1.91.21.3-1.9-1.41.8-1.8-1.81.61.6-1.91.9-1.71.41.7-1.61.61.6-1.61.4-1.6
Pavlov. Cond. response bias2.63.24.7-1.82.22.0-2.11.51.6-2.0-1.71.9-1.9-1.81.81.7-2.02.0-1.81.51.7-1.61.61.6-1.61.5-1.6
Pavlov. Cond. lever latency2.02.95.82.4-1.9-1.41.7-1.1-1.01.91.2-1.91.82.0-1.6-1.52.0-2.01.7-1.5-1.91.7-1.7-1.51.5-1.41.5
Pavlov. Cond. magazine entry latency0.70.92.00.5-0.9-1.21.0-1.3-1.40.81.3-0.90.90.7-1.1-1.10.6-0.61.0-1.1-0.90.8-0.9-0.90.9-1.10.9
Pavlov. Cond. change in total contacts0.30.82.6-1.60.90.2-0.6-0.0-0.0-1.0-0.11.0-0.9-1.30.50.5-1.21.2-0.80.71.0-0.90.90.9-0.80.6-0.9
Pavlov. Cond. index score0.10.20.9-1.00.3-0.2-0.1-0.4-0.5-0.40.30.4-0.3-0.70.00.0-0.60.6-0.30.10.4-0.40.30.2-0.20.0-0.2
Pavlov. Cond. latency score0.20.41.4-1.20.50.1-0.4-0.2-0.2-0.70.00.7-0.6-0.90.30.3-0.90.9-0.60.40.7-0.70.70.5-0.50.3-0.5
Pavlov. Cond. lever contacts1.31.94.6-2.11.61.1-1.30.80.8-1.6-0.91.6-1.5-1.71.21.2-1.71.7-1.41.21.5-1.41.31.2-1.21.0-1.2
Pavlov. Cond. magazine entry number0.10.10.50.7-0.10.4-0.00.60.70.3-0.5-0.20.20.50.10.10.5-0.50.1-0.0-0.30.3-0.3-0.20.20.00.2
Pavlov. Cond. intertrial magazine entries0.51.01.5-0.90.91.1-1.01.21.2-0.9-1.11.0-1.0-0.91.11.2-0.70.7-1.01.00.9-1.01.01.1-1.11.1-1.1
Pavlov. Cond. lever-magazine prob. diff.0.10.21.2-1.10.3-0.2-0.1-0.4-0.5-0.50.30.4-0.4-0.70.00.0-0.60.6-0.30.10.5-0.40.40.3-0.30.0-0.3
Pavlov. Cond. response bias0.40.62.3-1.50.90.4-0.6-0.0-0.1-0.9-0.10.9-0.8-1.10.50.4-1.01.0-0.70.40.8-0.80.70.6-0.60.4-0.6
Time in closed arm before self-admin0.00.10.4-0.0-0.3-0.20.2-0.1-0.30.20.1-0.00.10.10.1-0.2-0.10.1-0.1-0.10.2-0.30.1-0.6-0.20.20.6
Time in closed arm after self-admin0.10.10.5-0.3-0.3-0.50.2-0.7-0.7-0.00.60.0-0.0-0.3-0.1-0.10.1-0.1-0.1-0.00.1-0.30.40.1-0.40.2-0.1
Time in open arm before self-admin0.30.31.1-0.10.81.0-0.81.01.1-0.5-0.90.4-0.5-0.30.50.5-0.40.4-0.30.60.1-0.10.20.4-0.10.4-0.3
Time in open arm after self-admin0.70.82.8-0.21.01.3-1.01.61.7-0.8-1.50.7-0.7-0.50.91.0-0.70.7-0.70.90.6-0.50.40.6-0.40.6-0.6
Bone: periosteal estimation1.02.34.5-2.11.81.6-1.61.11.2-1.7-1.11.7-1.6-1.71.51.3-1.71.7-1.41.41.5-1.51.41.3-1.21.2-1.3
Bone: periosteal perimeter0.20.50.9-0.80.90.9-0.80.60.7-0.8-0.60.8-0.7-0.70.80.6-0.80.8-0.60.60.7-0.70.60.5-0.50.6-0.5
Bone: post-yield work0.71.12.6-0.91.51.6-1.51.21.4-1.2-1.21.1-1.1-0.91.11.0-1.01.0-1.01.10.7-0.60.70.7-0.80.8-0.7
Progressive ratio test 1 active lever presses0.10.21.51.2-0.20.4-0.11.00.90.3-0.8-0.10.10.50.30.40.3-0.3-0.10.10.1-0.20.1-0.10.10.50.1
Progressive ratio test 1 breakpoint0.10.21.21.1-0.10.5-0.21.00.90.2-0.8-0.0-0.00.40.40.50.2-0.2-0.20.20.2-0.30.2-0.0-0.00.60.0
Progressive ratio test 1 inactive lever presses0.20.62.7-0.40.91.3-0.91.61.4-0.6-1.40.7-0.7-0.30.90.8-0.40.4-0.60.50.5-0.40.30.2-0.40.6-0.2
Progressive ratio test 2 active lever presses0.20.31.61.3-0.50.10.30.60.50.6-0.3-0.50.50.8-0.1-0.10.6-0.60.4-0.3-0.50.4-0.4-0.50.4-0.10.5
Progressive ratio test 2 breakpoint0.20.31.71.3-0.50.00.40.60.50.7-0.3-0.50.50.9-0.2-0.10.6-0.60.4-0.4-0.50.4-0.5-0.60.4-0.10.6
Progressive ratio test 2 inactive lever presses0.20.71.8-0.50.70.9-0.71.41.2-0.6-1.20.7-0.7-0.60.91.0-0.70.7-0.70.70.9-0.80.70.6-0.80.9-0.6
Incentive Sensitization - Responses0.10.30.70.3-0.5-0.30.60.30.10.70.0-0.50.60.7-0.4-0.40.7-0.70.7-0.6-0.60.7-0.8-0.70.6-0.60.7
Incentive Sensitization - Breakpoint0.10.30.70.3-0.5-0.30.60.20.10.70.1-0.50.60.7-0.4-0.40.7-0.70.7-0.6-0.70.7-0.8-0.70.6-0.60.7
Sum of active levers in priming session hrs 5-62.92.76.72.6-1.7-1.21.5-1.0-0.91.91.1-1.81.82.0-1.5-1.31.8-1.81.7-1.7-1.91.8-1.8-1.41.7-1.41.3
Progressive ratio0.00.00.30.5-0.1-0.00.0-0.3-0.30.10.1-0.20.10.2-0.2-0.2-0.20.20.0-0.2-0.00.2-0.1-0.10.1-0.10.1
Food seeking constrained by brief footshock6.27.713.2-1.63.13.6-3.33.43.6-2.8-3.32.7-2.8-2.33.12.9-2.32.3-2.92.72.3-2.42.42.2-2.52.8-2.2
Seeking ratio, punishment vs. effort1.12.43.9-1.31.71.9-1.71.82.0-1.6-1.71.5-1.6-1.41.71.6-1.11.1-1.51.61.3-1.51.41.3-1.41.6-1.3
Retroperitoneal fat weight0.52.13.51.4-1.5-1.71.4-1.9-1.81.31.8-1.41.41.2-1.5-1.51.3-1.31.3-1.4-1.11.2-1.2-1.41.3-1.31.4
Reaction time number correct0.00.20.40.20.40.6-0.50.50.7-0.3-0.60.3-0.3-0.20.50.4-0.30.3-0.40.40.3-0.10.30.5-0.40.5-0.5
Reaction time mean minus median0.10.91.9-1.40.70.0-0.6-0.40.1-1.00.01.0-1.0-1.40.50.6-1.01.0-0.90.90.9-1.01.11.3-1.40.8-1.3
Reaction time mean minus median AUC0.21.32.4-1.21.00.5-1.1-0.10.4-1.3-0.31.2-1.2-1.50.90.9-1.21.2-1.21.11.2-1.21.21.6-1.51.1-1.6
Reaction time num false alarms0.10.20.90.30.0-0.2-0.2-0.9-1.0-0.20.60.0-0.1-0.2-0.1-0.1-0.50.5-0.2-0.50.2-0.20.20.5-0.40.1-0.4
Reaction time num false alarms AUC0.20.30.80.00.60.5-0.7-0.3-0.2-0.6-0.10.5-0.5-0.50.50.4-0.90.9-0.7-0.00.6-0.60.60.9-0.70.6-0.8
Reaction time trials correct on left0.00.20.40.20.40.6-0.50.50.7-0.3-0.60.3-0.3-0.20.50.4-0.30.3-0.40.40.3-0.10.30.5-0.40.5-0.5
Reaction time trials on left0.00.10.30.30.30.5-0.40.40.6-0.2-0.50.2-0.2-0.10.40.3-0.20.2-0.30.30.2-0.00.20.4-0.30.4-0.4
Reaction time mean0.81.85.41.0-1.5-2.01.5-2.3-2.01.22.1-1.31.30.9-1.6-1.40.9-0.91.3-1.2-1.00.8-0.9-0.90.8-1.20.9
Reaction time mean AUC0.81.95.41.0-1.6-2.11.5-2.3-2.01.22.1-1.31.30.9-1.6-1.50.9-0.91.3-1.2-1.00.8-0.9-0.90.8-1.20.9
Median of all reaction times2.84.47.72.0-2.4-2.62.2-2.8-2.52.02.6-2.22.11.8-2.3-2.21.7-1.72.1-2.0-1.91.7-1.7-1.81.7-2.01.8
Reaction time omissions2.03.33.81.8-1.8-1.81.8-1.7-1.61.81.7-1.91.91.8-1.9-1.81.8-1.81.9-1.7-1.71.8-1.9-1.81.8-1.91.8
Reaction time false alarm rate0.10.11.00.3-0.2-0.30.1-1.0-1.00.00.7-0.10.1-0.0-0.2-0.2-0.20.20.0-0.60.0-0.1-0.00.2-0.1-0.1-0.1
Reaction time premature initiation rate0.50.82.10.0-1.3-1.41.3-1.2-1.41.01.3-0.70.80.5-0.8-0.71.1-1.10.8-0.8-0.40.3-0.5-0.40.5-0.50.4
Reaction time premature initiations0.10.40.90.3-0.9-1.00.9-0.9-0.90.70.8-0.50.50.4-0.5-0.40.8-0.80.4-0.6-0.20.2-0.3-0.10.2-0.20.1
Std. dev. reaction times0.10.31.8-0.2-0.4-1.00.4-1.4-0.90.11.1-0.20.2-0.2-0.6-0.5-0.10.10.3-0.2-0.1-0.1-0.10.1-0.1-0.4-0.1
Reaction time trials completed0.00.10.30.30.30.5-0.40.40.6-0.2-0.50.2-0.2-0.10.40.3-0.20.2-0.30.30.2-0.00.20.4-0.30.4-0.4
Reaction time trials AUC0.00.10.30.30.30.5-0.40.40.6-0.2-0.60.2-0.3-0.10.40.3-0.20.2-0.30.30.2-0.00.20.4-0.30.4-0.4
Run reversals in cocaine runway, females0.10.11.0-1.00.1-0.20.0-0.0-0.1-0.30.10.3-0.3-0.50.10.2-0.20.2-0.40.40.1-0.30.50.4-0.50.1-0.4
Run reversals in cocaine runway, males0.00.00.1-0.30.0-0.00.10.1-0.00.0-0.10.1-0.0-0.10.00.0-0.00.00.00.00.0-0.00.00.20.0-0.0-0.1
Latency to leave start box in cocaine runway0.71.01.7-0.50.90.9-1.00.90.9-1.0-1.00.9-1.0-0.91.01.1-1.11.1-1.01.00.9-0.91.11.2-1.01.1-1.3
Latency to leave start box in cocaine runway, F0.00.00.40.6-0.2-0.00.10.20.20.2-0.2-0.20.20.3-0.10.1-0.00.00.1-0.1-0.10.1-0.20.00.10.0-0.0
Latency to leave start box in cocaine runway, M1.61.62.0-1.11.41.4-1.41.31.3-1.3-1.31.3-1.3-1.21.31.3-1.21.2-1.31.21.0-1.01.21.3-1.01.2-1.4
Std. dev. time between licks in bursts0.40.71.50.3-0.7-0.90.9-1.0-1.20.81.0-0.80.80.7-0.9-0.90.6-0.60.9-1.0-0.70.8-0.9-0.80.8-1.00.8
Total sessions with >9 infusions0.10.10.90.60.10.5-0.20.90.90.1-0.80.0-0.00.30.30.3-0.10.1-0.00.20.2-0.1-0.00.0-0.10.3-0.0
Short access day 1 total inactive lever presses0.50.92.7-0.90.91.2-0.81.71.4-0.7-1.40.9-0.9-0.61.11.1-0.60.6-0.80.80.9-0.70.70.8-0.81.0-0.8
Short access day 10 total inactive lever presses0.10.81.8-1.31.00.9-0.80.90.8-0.9-0.91.0-0.9-1.00.90.9-0.70.7-0.90.60.8-0.90.80.9-0.80.7-0.9
Short access day 1 total infusions0.10.21.00.60.10.6-0.30.91.00.1-0.80.0-0.10.30.40.4-0.00.0-0.10.20.2-0.1-0.10.1-0.00.3-0.1
Short access day 10 total infusions0.10.21.41.2-0.20.4-0.10.80.70.3-0.6-0.20.20.60.10.20.5-0.50.10.0-0.10.2-0.1-0.10.10.20.1
Short access total infusions0.10.20.91.0-0.30.30.10.80.70.5-0.6-0.30.30.70.00.10.5-0.50.3-0.1-0.30.3-0.3-0.30.2-0.00.3
Short access day 1 locomotion0.40.73.21.8-1.1-0.70.9-0.4-0.21.10.3-1.01.01.1-0.7-0.60.6-0.60.8-0.5-0.50.6-0.7-0.70.7-0.50.7
Short access day 10 total locomotion0.10.31.51.2-0.9-0.90.6-0.7-0.60.60.6-0.60.60.5-0.6-0.50.2-0.20.5-0.40.10.0-0.3-0.30.3-0.30.3
Short access total locomotion0.10.21.81.3-0.6-0.30.4-0.1-0.00.60.0-0.50.50.7-0.3-0.30.3-0.30.4-0.4-0.00.2-0.4-0.50.5-0.20.5
One hour access (0.3 mA shock)0.50.62.20.10.61.0-0.81.51.5-0.5-1.30.6-0.6-0.30.80.9-0.30.3-0.60.80.4-0.50.50.6-0.60.8-0.6
Compulsive drug intake0.20.30.7-0.60.50.2-0.50.40.6-0.6-0.50.5-0.5-0.70.30.5-0.40.4-0.40.80.2-0.40.40.8-0.70.3-0.8
One hour access (shock baseline)0.10.31.40.70.30.9-0.51.21.1-0.1-1.00.2-0.30.20.60.5-0.00.0-0.40.30.3-0.10.3-0.1-0.10.60.1
Social response proportion3.74.78.31.8-2.2-2.52.2-2.9-2.82.02.7-2.12.11.8-2.4-2.42.0-2.02.1-2.3-1.82.0-1.9-1.92.0-2.11.9
Social responses0.10.20.4-0.40.60.5-0.60.00.1-0.6-0.20.4-0.5-0.50.30.3-0.60.6-0.30.20.5-0.40.40.4-0.20.2-0.4
Social time1.82.84.21.5-1.2-1.41.3-2.0-2.01.41.9-1.61.61.5-1.9-1.91.3-1.31.7-2.0-1.81.9-1.8-1.51.7-2.01.5
Soleus weight0.82.54.51.7-0.8-0.31.0-0.5-0.51.40.7-1.61.51.9-1.4-1.51.6-1.61.7-1.7-1.92.0-2.1-2.02.1-1.92.0
Bone: stiffness1.12.15.2-2.32.11.6-1.70.70.7-1.8-0.71.7-1.6-1.81.31.0-1.81.8-1.41.01.3-1.11.11.2-1.20.9-1.2
Tibialis anterior weight5.418.727.3-4.65.25.2-4.84.64.6-4.6-4.64.6-4.5-4.24.64.3-4.24.2-4.34.03.8-3.73.83.7-3.73.8-3.7
Time to tail flick, vehicle, before self-admin0.00.00.1-0.2-0.2-0.20.2-0.2-0.30.10.20.1-0.0-0.10.1-0.0-0.30.3-0.00.10.2-0.40.2-0.00.00.20.1
Time to tail flick, vehicle, after self-admin0.10.30.7-0.30.40.4-0.50.50.6-0.5-0.60.5-0.5-0.50.50.4-0.50.5-0.50.80.8-0.60.60.3-0.70.6-0.1
Time to tail flick, test, before self-admin0.30.40.6-0.40.70.8-0.80.20.3-0.7-0.40.7-0.7-0.70.70.5-0.60.6-0.80.30.7-0.70.70.6-0.60.8-0.6
Time to tail flick, test, after self-admin4.24.56.4-1.81.91.6-2.11.21.3-2.2-1.62.2-2.2-2.32.12.2-2.22.2-2.32.12.5-2.42.42.4-2.22.3-2.4
Delta time to tail flick, vehicle, before/after SA0.00.00.10.30.10.0-0.1-0.20.0-0.10.1-0.10.10.0-0.2-0.20.3-0.30.1-0.10.00.3-0.1-0.2-0.0-0.20.2
Delta time to tail flick, test, before/after SA0.30.30.7-0.80.30.0-0.20.10.1-0.5-0.20.6-0.5-0.70.40.6-0.70.7-0.50.70.8-0.80.70.7-0.70.5-0.8
Tibia length0.82.14.40.5-0.8-0.71.2-0.9-1.11.31.2-1.31.31.4-1.4-1.71.1-1.11.5-1.6-2.12.0-1.8-1.81.8-1.91.7
Ambulatory time before self-admin0.62.04.7-1.41.71.9-1.52.22.1-1.3-2.01.4-1.3-1.11.41.4-1.11.1-1.11.41.0-1.00.81.1-0.81.0-1.1
Ambulatory time after self-admin0.10.20.5-0.70.50.4-0.30.70.6-0.3-0.60.3-0.3-0.30.20.4-0.50.5-0.10.30.3-0.00.00.4-0.0-0.0-0.4
Bone: tissue strength0.30.40.70.2-0.3-0.50.4-0.9-0.70.30.8-0.50.50.3-0.7-0.80.5-0.50.5-0.6-0.80.7-0.6-0.60.6-0.80.5
Total heroin consumption1.61.83.92.0-1.3-0.71.2-0.4-0.41.50.7-1.41.41.7-1.1-1.21.5-1.51.4-1.3-1.51.5-1.6-1.51.6-1.21.5
Bone: trabecular number1.32.45.0-2.21.71.3-1.41.31.1-1.7-1.41.7-1.7-1.81.51.5-1.71.7-1.61.41.4-1.41.51.6-1.61.4-1.6
Bone: trabecular spacing0.00.00.10.4-0.1-0.2-0.0-0.00.1-0.1-0.1-0.0-0.0-0.10.00.1-0.10.1-0.10.30.2-0.20.30.1-0.10.2-0.1
Bone: trabecular thickness0.00.10.5-0.2-0.1-0.30.2-0.7-0.70.10.6-0.00.0-0.1-0.1-0.2-0.10.10.0-0.30.00.00.00.1-0.1-0.0-0.2
Bone: trabecular tissue density0.51.03.3-1.81.61.3-1.11.01.0-1.2-1.01.1-1.0-1.10.80.7-1.11.1-0.80.80.7-0.50.50.5-0.40.2-0.5
Water consumed over 24 hours0.91.72.1-1.21.21.2-1.31.31.3-1.3-1.31.4-1.3-1.31.41.4-1.31.3-1.41.41.3-1.41.41.3-1.31.4-1.3
Number of responses in last shaping day0.70.92.01.3-0.60.00.60.60.41.0-0.1-0.90.91.3-0.6-0.71.4-1.40.9-0.8-1.41.3-1.1-1.01.1-0.81.0