Hub : Genes

Clptm1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Clptm1 0.62 0.23 9.3e-08 0.1 0.1 0.07 0.09 3.3e-06 7.2e-06 8.9e-05 1.5e-05
2 NAcc gene expression Clptm1 0.05 0.03 1.5e-07 0.04 0.04 0.04 0.04 8.0e-07 3.9e-07 5.2e-07 9.0e-07
3 Adipose mRNA stability Clptm1 0.08 0.05 4.4e-08 0.06 0.06 0.06 0.07 1.5e-07 1.1e-07 6.3e-07 7.3e-08
4 LHb gene expression Clptm1 0.23 0.14 3.1e-04 0.13 0.1 0.14 0.13 4.6e-04 2.0e-03 4.4e-04 5.1e-04
5 PL gene expression Clptm1 0.06 0.04 9.7e-08 0.06 0.06 0.04 0.05 5.0e-07 4.5e-07 1.8e-05 2.5e-06
6 pVTA gene expression Clptm1 0.09 0.06 2.3e-06 0.03 0.04 0.04 0.04 3.1e-03 3.2e-04 1.9e-04 6.1e-04
7 Brain gene expression Clptm1 0.16 0.08 1.1e-16 0.18 0.16 0.17 0.17 2.1e-16 5.4e-15 5.8e-16 4.0e-16
8 Liver gene expression Clptm1 0.03 0.03 7.5e-03 0.01 0.01 0.01 0.01 2.7e-02 1.2e-02 5.5e-02 2.7e-02
9 IC gene expression Clptm1 0.14 0.09 2.4e-04 0.05 0.07 0.06 0.06 3.7e-03 8.3e-04 1.2e-03 2.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.00.10.2-0.10.20.2-0.40.1-0.4-0.40.4-0.1
Area under the delay curve1.52.23.61.3-1.2-1.60.9-1.71.81.8-0.6-1.9
BMI with tail0.62.23.8-1.31.71.4-1.91.4-1.1-1.61.60.8
BMI without tail0.31.62.0-1.41.41.4-1.41.2-1.0-1.21.20.9
Body weight1.14.87.4-2.12.52.2-2.71.9-1.6-2.42.61.1
Weight adjusted by age0.00.00.00.0-0.0-0.00.00.1-0.10.1-0.10.2
Bone surface0.30.71.1-0.70.90.8-1.10.7-0.6-1.01.00.4
Bone volume0.30.51.0-0.60.80.7-1.00.5-0.4-0.81.00.1
Breakpoint value in progressive ratio session1.22.23.01.7-1.5-1.61.3-1.71.21.5-1.1-1.6
Number of licking bursts0.82.33.6-1.91.71.4-1.51.3-1.1-1.71.80.9
Context. condit. distance diff. score0.10.20.4-0.20.50.4-0.60.3-0.1-0.50.60.1
Locomotion velocity, session 10.10.10.40.3-0.1-0.30.0-0.40.40.20.2-0.6
Locomotion distance, session 10.10.20.4-0.50.40.4-0.40.2-0.1-0.60.6-0.1
Locomotion velocity, session 20.81.02.1-1.10.91.0-0.61.1-1.5-0.90.61.2
Locomotion distance, session 20.40.61.1-0.80.60.8-0.40.9-1.1-0.80.30.9
Locomotion velocity, session 30.20.20.7-0.40.30.5-0.10.6-0.6-0.3-0.10.8
Locomotion distance, session 31.01.13.31.1-1.3-0.81.5-0.40.10.9-1.80.4
Stereotopy head waving bouts, day 30.60.72.2-0.80.60.7-0.31.1-1.1-0.3-0.21.5
Stereotopy head waving duration, day 30.70.91.2-1.11.01.0-1.01.1-0.8-0.70.71.0
Locomotion velocity, session 70.10.10.30.6-0.2-0.10.1-0.1-0.20.0-0.2-0.1
Locomotion distance, session 70.10.20.60.10.40.3-0.60.2-0.8-0.30.5-0.0
Stereotopy head waving bouts, day 70.70.91.3-1.00.91.0-0.81.1-0.8-1.00.51.1
Stereotopy head waving duration, day 70.50.60.9-0.90.90.9-0.80.9-0.6-0.80.70.8
Locomotion velocity, session 80.10.20.50.2-0.4-0.10.60.0-0.10.3-0.70.4
Locomotion distance, session 80.10.10.2-0.00.20.4-0.30.2-0.4-0.40.30.1
Degree of sensitization distance1.01.13.3-0.71.20.8-1.60.3-0.4-0.71.8-0.5
Degree of sensitization stereotypy0.80.91.2-1.10.91.0-0.91.1-0.6-1.00.71.1
Conditioned locomotion0.60.72.60.2-0.7-0.21.10.4-0.50.1-1.61.3
Cocaine response after cond. corrected0.60.91.8-0.70.80.8-0.61.1-1.3-1.10.31.2
Cocaine response after cond. not corrected1.62.45.1-1.21.21.4-1.01.8-2.2-1.70.42.0
Cocaine response before conditioning1.72.03.8-1.41.11.4-0.91.6-2.0-1.40.41.9
Saline control response1.52.12.8-1.61.61.7-1.61.4-1.0-1.41.61.0
Bone: connectivity density0.00.00.10.00.10.0-0.2-0.10.1-0.10.2-0.2
Bone: cortical apparent density0.10.10.30.4-0.2-0.10.1-0.40.50.20.1-0.6
Bone: cortical area1.22.02.6-1.61.61.5-1.51.3-1.2-1.41.60.9
Bone: cortical porosity1.31.44.60.6-1.2-0.71.70.0-1.00.8-2.11.2
Bone: cortical porosity0.80.92.80.2-0.8-0.21.20.4-1.00.5-1.71.3
Bone: cortical thickness0.50.81.1-1.10.91.0-0.90.9-0.8-0.80.90.7
Bone: cortical thickness1.41.73.5-1.41.21.3-1.11.3-1.9-1.20.91.2
Bone: cortical tissue density0.10.20.40.5-0.3-0.20.2-0.50.50.3-0.1-0.6
Condit. Reinf. active minus inactive responses0.50.60.9-0.60.80.7-0.80.8-0.9-0.90.60.6
Condit. Reinf. active-inactive response ratio0.50.61.0-0.60.80.8-1.00.7-0.6-1.00.70.5
Condit. Reinf. active responses0.40.50.8-0.60.60.7-0.70.7-0.9-0.70.50.6
Condit. Reinf. inactive responses0.00.00.0-0.0-0.00.10.00.0-0.20.1-0.0-0.0
Incentive salience index mean0.30.41.0-0.40.40.6-0.40.7-1.0-0.70.20.8
Condit. Reinf. lever presses0.00.00.10.0-0.00.10.10.2-0.3-0.3-0.20.3
Condit. Reinf. active minus inactive responses0.20.20.5-0.40.30.4-0.30.6-0.7-0.60.10.6
Condit. Reinf. active-inactive response ratio0.61.02.4-0.70.60.9-0.61.3-1.3-1.2-0.11.6
Condit. Reinf. active responses0.10.10.30.2-0.4-0.30.4-0.2-0.20.3-0.60.1
Condit. Reinf. inactive responses0.71.01.90.8-1.0-1.01.0-1.10.71.4-0.8-1.0
Condit. Reinf. lever presses0.30.41.0-0.50.80.5-1.00.3-0.6-0.61.0-0.1
Condit. Reinf. lever reinforcers received0.10.20.50.3-0.5-0.30.5-0.1-0.20.3-0.70.2
Conditioned reinforcement - actives0.52.02.6-1.51.41.5-1.41.6-1.2-1.31.01.5
Conditioned reinforcement - inactives0.20.50.7-0.70.60.7-0.70.8-0.5-0.70.30.9
Conditioned locomotion2.03.03.6-1.81.71.8-1.71.9-1.9-1.81.21.8
Patch foraging indifference point 0 sec0.20.71.2-1.00.80.7-0.50.8-1.1-0.90.60.8
Patch foraging indifference point AUC1.33.04.2-2.01.82.0-1.61.9-1.3-1.71.51.7
Delay disc. indifference point, 0s delay1.41.52.31.2-1.4-1.21.4-1.11.01.5-1.3-0.8
Delay disc. indifference point, 16s delay1.01.53.51.1-0.8-1.20.6-1.51.21.5-0.1-1.9
Delay disc. indifference point, 2s delay4.14.58.01.9-1.7-2.31.3-2.62.62.3-0.8-2.8
Delay disc. indifference point, 24s delay0.30.41.6-0.30.70.4-1.20.2-0.3-0.51.1-0.4
Delay disc. indifference point, 4s delay0.00.00.1-0.1-0.1-0.10.1-0.00.40.4-0.20.1
Delay disc. indifference point, 8s delay1.32.33.61.3-1.2-1.61.1-1.71.91.8-0.7-1.8
Indifference point function ln k0.30.91.11.0-1.0-1.00.8-1.10.91.0-0.7-1.0
Indifference point function log k0.30.91.11.0-1.0-1.00.8-1.10.91.0-0.7-1.0
Patch foraging total patch changes 0 sec0.41.11.7-1.31.11.0-1.01.0-1.1-1.11.10.7
Patch foraging total patch changes 12 sec1.11.52.5-1.31.01.1-0.71.4-1.6-1.30.41.6
Patch foraging total patch changes 18 sec1.22.93.9-1.91.91.7-1.91.6-1.3-1.92.01.0
Patch foraging total patch changes 24 sec0.10.50.6-0.80.80.7-0.70.7-0.8-0.60.70.6
Patch foraging total patch changes 6 sec1.83.14.8-2.21.71.9-1.31.9-1.9-1.61.11.9
Patch foraging time to switch 0 sec1.35.16.02.5-2.3-2.42.2-2.42.32.2-1.8-2.2
Patch foraging water rate 0 sec1.55.66.8-2.62.52.6-2.22.6-2.3-2.31.92.3
Patch foraging water rate 12 sec0.10.40.7-0.60.80.7-0.80.6-0.4-0.50.80.3
Patch foraging water rate 18 sec0.10.31.1-0.50.70.5-0.80.2-0.1-0.31.0-0.2
Patch foraging water rate 24 sec0.50.81.1-1.01.01.0-1.00.9-0.4-0.81.00.6
Patch foraging water rate 6 sec1.01.53.6-1.11.51.2-1.70.7-0.3-1.11.9-0.1
Seeking ratio, delayed vs. immediate footshock1.42.13.31.6-1.7-1.41.8-1.30.91.4-1.7-0.7
Distance traveled before self-admin0.10.10.3-0.40.30.2-0.30.3-0.4-0.50.30.2
Distance traveled after self-admin0.20.30.70.4-0.6-0.40.8-0.30.40.5-0.70.0
Extensor digitorum longus weight1.56.110.7-2.62.92.5-2.92.0-1.7-2.53.31.0
Bone: elastic displacement0.81.11.61.2-1.2-1.01.2-0.90.21.2-1.3-0.5
Bone: elastic work0.20.31.4-0.1-0.10.20.20.4-1.2-0.0-0.60.8
Bone: endosteal estimation0.00.00.10.3-0.1-0.1-0.1-0.1-0.1-0.0-0.1-0.1
Bone: endosteal perimeter0.00.10.20.00.1-0.1-0.2-0.20.3-0.10.4-0.5
Epididymis fat weight0.21.01.11.0-1.0-1.01.1-1.01.01.0-0.8-0.9
Delta time in closed arm before/after self-admin0.20.10.60.20.0-0.2-0.2-0.40.30.40.4-0.7
Delta time in open arm before/after self-admin0.10.10.30.1-0.3-0.10.4-0.00.10.3-0.50.2
Diff in mean of infusions in LGA sessions0.81.41.91.3-1.2-1.31.0-1.41.01.2-0.8-1.3
Delay discount exponential model param1.21.62.9-1.10.91.4-0.71.5-1.7-1.50.41.7
Extinction: sum of active levers before priming0.20.30.70.3-0.5-0.10.7-0.1-0.60.5-0.80.3
Active lever presses in extinction session 60.20.20.7-0.20.40.3-0.60.1-0.8-0.60.6-0.1
Bone: final force0.30.60.8-0.80.80.7-0.70.8-0.9-0.70.60.7
Bone: final moment0.50.81.0-0.90.90.8-0.81.0-1.0-0.80.61.0
Food consumed during 24 hour testing period2.55.16.62.6-2.4-2.42.2-2.31.82.4-2.2-1.9
Glucose0.30.40.80.8-0.7-0.80.5-0.50.50.8-0.9-0.2
Heart weight1.82.93.4-1.81.81.8-1.61.7-1.7-1.71.51.5
Delay discount hyperbolic model param1.21.62.9-1.00.91.4-0.61.5-1.6-1.50.31.7
Intermittent access intake day 1-15 change0.10.30.8-0.40.60.4-0.90.1-0.2-0.30.9-0.3
Intermittent access intake escalation0.10.40.9-0.50.70.5-1.00.3-0.3-0.31.0-0.2
Intermittent access intake escalation 20.00.00.2-0.10.10.1-0.10.2-0.4-0.0-0.10.3
Intermitt. access day 1 inactive lever presses0.00.00.1-0.00.10.0-0.3-0.00.3-0.00.2-0.1
Intermitt. access day 15 inactive lever presses0.10.41.0-0.00.40.0-0.7-0.40.90.11.0-1.0
Intermitt. access escalation Index0.10.30.50.6-0.5-0.60.5-0.70.50.5-0.2-0.7
Intermittent access day 1 total infusions0.61.92.4-1.51.51.5-1.41.5-1.2-1.11.11.3
Intermittent access day 15 total infusions0.41.12.3-1.11.31.1-1.50.8-0.5-0.61.40.3
Intermittent access terminal intake (last 3 days)0.81.32.5-1.31.41.3-1.61.0-0.6-0.81.50.5
Intermittent access total infusions2.22.64.1-1.71.91.7-2.01.5-1.1-1.31.71.0
Intermittent access day 1 locomotion0.30.51.2-0.60.50.7-0.40.9-1.0-0.6-0.01.1
Intermittent access day 15 total locomotion0.10.20.3-0.50.50.5-0.60.5-0.5-0.30.40.4
Intermittent access total locomotion1.51.92.2-1.41.41.4-1.51.5-1.4-1.21.01.3
Intermittent access standard deviation0.00.20.40.4-0.4-0.50.2-0.50.70.6-0.3-0.5
Left kidney weight3.124.628.7-5.15.05.3-4.75.2-5.4-5.24.04.6
Right kidney weight3.121.924.4-4.84.84.9-4.64.8-4.9-4.94.04.1
Cocaine induced anxiety0.20.72.60.6-0.3-0.60.1-0.81.60.80.1-1.1
Post-drug Anxiety0.20.31.10.3-0.1-0.3-0.0-0.51.10.50.2-0.8
Baseline Anxiety0.10.10.5-0.0-0.10.00.30.2-0.7-0.1-0.40.5
Tail length0.20.91.6-1.31.01.1-1.00.9-0.7-0.91.00.7
Length with tail0.31.32.0-1.21.31.1-1.31.0-0.9-1.11.40.5
Length without tail0.41.94.2-1.11.61.1-2.00.9-0.7-1.52.10.0
Times rat made contact with spout0.10.10.70.00.00.2-0.10.3-0.8-0.4-0.20.4
Lifetime Intake1.92.43.5-1.71.81.7-1.91.5-1.2-1.31.61.2
Liver weight, left1.52.74.3-1.91.51.7-1.11.8-2.1-1.40.91.9
Liver weight, right1.32.33.0-1.61.61.6-1.71.5-1.3-1.61.51.1
Locomotor activity1.32.03.4-1.91.51.7-1.11.5-1.1-1.31.21.4
Locomotor testing distance0.51.22.2-1.51.21.3-0.91.1-0.6-0.91.10.9
Locomotor testing rearing1.96.98.8-3.02.92.9-2.72.6-2.1-2.72.62.1
Locomotion in novel chamber0.10.20.30.4-0.4-0.40.4-0.50.50.3-0.2-0.5
Locomotion in novel chamber post-restriction0.51.42.21.0-1.2-1.11.3-1.11.51.5-1.1-0.9
Fecal boli incidents, locomotor time 10.00.00.2-0.10.10.1-0.10.1-0.4-0.10.10.1
Change in fecal boli incidents, locomotor task0.70.71.10.8-0.8-1.10.6-1.01.00.8-0.6-0.9
Time >=10cm from walls, locomotor time 10.10.10.20.10.30.3-0.50.0-0.3-0.00.4-0.2
Bouts of movement, locomotor time 11.72.23.31.7-1.3-1.51.1-1.61.81.5-0.9-1.6
Total resting periods, locomotor time 12.52.94.41.9-1.5-1.71.3-1.92.11.8-1.0-1.9
Rest time, locomotor task time 10.10.20.30.5-0.3-0.40.2-0.50.50.4-0.2-0.5
Distance moved, locomotor task time 10.20.51.5-0.80.40.6-0.20.9-1.1-0.6-0.21.2
Vertical activity count, locomotor time 10.00.30.80.1-0.5-0.20.70.1-0.60.1-0.90.6
Time >=10cm from walls, locomotor time 20.10.20.70.3-0.4-0.30.40.00.10.3-0.80.4
Bouts of movement, locomotor time 21.65.37.62.7-2.2-2.51.7-2.72.32.2-1.3-2.8
Total resting periods, locomotor time 21.14.66.72.5-2.0-2.31.7-2.52.12.0-1.2-2.6
Rest time, locomotor task time 20.00.10.20.2-0.20.00.5-0.00.4-0.1-0.30.1
Distance moved, locomotor task time 20.70.91.9-1.00.70.7-0.71.1-1.4-1.00.21.2
Vertical activity count, locomotor time 20.10.10.30.3-0.4-0.60.3-0.3-0.10.3-0.4-0.2
Light reinforcement 10.10.41.3-0.30.50.7-0.70.6-1.2-0.50.30.6
Light reinforcement 20.10.10.3-0.20.40.5-0.50.1-0.4-0.20.6-0.1
Bone: marrow area0.00.00.10.3-0.1-0.1-0.1-0.0-0.1-0.1-0.1-0.0
Bone: maximum diameter1.83.64.7-2.02.12.0-2.01.7-1.7-2.12.21.1
Bone: maximum force0.10.30.4-0.60.60.5-0.60.5-0.5-0.40.50.4
Bone: maximum moment0.20.40.5-0.70.60.5-0.60.7-0.6-0.50.50.6
Mean time between licks in bursts0.00.20.4-0.0-0.4-0.30.5-0.1-0.40.4-0.70.2
Mean num. licks in bursts0.72.04.21.9-1.7-1.31.5-1.00.51.4-2.0-0.4
Cd content in liver0.10.10.20.20.20.0-0.50.00.0-0.40.3-0.2
Co content in liver1.11.32.51.3-1.4-1.31.4-0.90.41.0-1.6-0.3
Cu content in liver0.20.20.8-0.50.60.3-0.50.3-0.1-0.50.9-0.1
Fe content in liver3.54.38.3-2.52.42.1-2.31.5-1.4-2.12.90.7
K content in liver0.10.10.2-0.30.0-0.10.30.2-0.4-0.1-0.10.4
Mg content in liver0.40.51.4-0.70.30.4-0.00.8-1.1-0.5-0.21.2
Mn content in liver2.12.38.2-0.90.40.90.11.9-2.3-1.0-1.12.9
Na content in liver0.10.10.5-0.40.20.2-0.10.3-0.7-0.00.10.3
Rb content in liver0.30.31.1-0.40.50.4-0.60.4-1.1-0.60.60.1
Se content in liver2.32.74.6-2.11.61.8-1.21.8-1.5-1.61.11.8
Sr content in liver0.10.10.2-0.0-0.10.10.30.1-0.10.1-0.40.4
Zn content in liver0.70.81.3-0.70.90.7-0.90.9-1.1-1.00.80.8
Bone: minimum diameter0.20.40.6-0.60.70.6-0.70.6-0.7-0.50.60.4
Time in familiar zone, hab. session 10.10.20.4-0.20.40.4-0.50.3-0.6-0.30.50.2
Time in novel zone, hab. session 10.50.60.8-0.90.70.7-0.80.8-0.7-0.70.50.8
Total zone transitions, hab. session 10.30.50.9-0.70.70.7-0.70.5-1.0-0.60.70.3
Total locomotion distance, hab. session 10.30.40.70.4-0.7-0.80.8-0.80.30.8-0.5-0.7
Locomotion velocity, hab. session 11.01.41.91.0-1.2-1.31.2-1.40.91.3-0.9-1.3
Time in familiar zone, hab. session 20.40.41.5-0.60.70.3-0.8-0.00.3-0.31.2-0.6
Time in novel zone, hab. session 20.00.10.20.3-0.1-0.1-0.00.1-0.30.1-0.40.3
Total zone transitions, hab. session 20.50.61.5-0.80.60.7-0.40.9-1.2-0.90.21.0
Total locomotion distance, hab. session 20.50.61.00.8-0.9-1.01.0-0.80.20.7-0.9-0.5
Locomotion velocity, hab. session 20.30.40.80.6-0.8-0.70.9-0.5-0.10.5-0.9-0.2
Novel to familiar place preference ratio0.91.21.8-0.91.21.3-1.31.1-0.8-1.21.00.8
Novelty place preference0.81.11.6-0.81.11.2-1.21.1-0.9-1.10.90.9
Time in novel zone, NPP test1.11.32.0-0.91.21.3-1.41.2-1.0-1.21.01.0
Total zone transitions, NPP test0.10.20.4-0.30.40.4-0.30.2-0.5-0.50.6-0.0
Total locomotion distance, NPP test0.20.20.8-0.30.50.4-0.60.1-0.4-0.60.9-0.3
Locomotion velocity, NPP test0.10.20.7-0.30.50.3-0.40.0-0.3-0.60.8-0.3
Intraocular pressure0.10.10.30.10.3-0.1-0.6-0.00.1-0.30.5-0.3
Delta distance traveled before/after self-admin1.71.92.71.4-1.5-1.31.5-1.31.31.6-1.4-1.0
Delta ambulatory time before/after self-admin0.30.50.90.7-0.8-0.60.9-0.60.41.0-1.0-0.2
Parametrial fat weight0.10.20.6-0.30.20.4-0.00.5-0.6-0.3-0.20.8
Pavlov. Cond. lever latency0.50.61.50.7-0.7-0.80.5-0.91.20.9-0.4-0.9
Pavlov. Cond. magazine entry latency0.20.30.7-0.40.50.3-0.70.1-0.3-0.70.9-0.3
Pavlov. Cond. change in total contacts0.30.40.60.7-0.7-0.70.7-0.50.30.3-0.8-0.3
Pavlov. Cond. index score0.30.41.0-0.50.50.5-0.50.6-1.0-0.90.50.5
Pavlov. Cond. latency score0.10.10.5-0.20.20.2-0.10.2-0.7-0.50.10.2
Pavlov. Cond. lever contacts0.30.41.1-0.50.50.6-0.40.6-1.1-0.80.40.6
Pavlov. Cond. magazine entry number0.10.10.30.1-0.3-0.00.4-0.00.40.6-0.50.2
Pavlov. Cond. intertrial magazine entries0.20.31.2-0.30.20.4-0.10.7-0.5-0.2-0.41.1
Pavlov. Cond. lever-magazine prob. diff.0.40.51.4-0.60.50.5-0.40.7-1.2-0.90.30.7
Pavlov. Cond. response bias1.01.22.1-1.01.21.0-1.20.9-1.2-1.41.20.6
Pavlov. Cond. lever latency0.00.00.10.2-0.2-0.10.3-0.10.10.3-0.2-0.0
Pavlov. Cond. magazine entry latency0.40.61.8-0.20.80.5-1.40.4-0.5-0.91.0-0.1
Pavlov. Cond. change in total contacts0.00.10.20.3-0.1-0.3-0.3-0.30.20.00.1-0.5
Pavlov. Cond. index score0.10.20.70.00.40.1-0.80.0-0.1-0.40.6-0.4
Pavlov. Cond. latency score0.10.10.40.10.2-0.1-0.6-0.10.1-0.20.5-0.5
Pavlov. Cond. lever contacts0.10.20.4-0.30.50.3-0.60.2-0.2-0.60.6-0.0
Pavlov. Cond. magazine entry number0.30.41.4-0.5-0.20.40.80.5-0.60.1-0.81.2
Pavlov. Cond. intertrial magazine entries0.10.20.6-0.2-0.4-0.00.80.0-0.50.3-0.70.5
Pavlov. Cond. lever-magazine prob. diff.0.20.30.9-0.20.50.2-0.90.2-0.2-0.60.7-0.2
Pavlov. Cond. response bias0.10.10.3-0.00.30.1-0.50.1-0.2-0.50.4-0.1
Time in closed arm before self-admin0.61.11.4-1.11.11.0-1.20.9-1.0-1.11.20.6
Time in closed arm after self-admin0.91.13.40.8-0.4-0.90.0-1.31.31.00.4-1.8
Time in open arm before self-admin0.81.01.61.1-1.1-1.01.2-0.80.61.1-1.3-0.4
Time in open arm after self-admin0.70.82.80.5-0.9-0.31.30.1-0.40.5-1.71.0
Bone: periosteal estimation0.20.60.8-0.70.80.8-0.90.7-0.7-0.80.80.5
Bone: periosteal perimeter0.20.40.9-0.70.70.6-0.80.4-0.4-0.70.90.1
Bone: post-yield work0.50.92.00.8-0.7-0.90.5-1.21.40.9-0.2-1.4
Progressive ratio test 1 active lever presses1.42.43.7-1.81.51.8-1.21.8-1.4-1.40.91.9
Progressive ratio test 1 breakpoint1.32.13.6-1.71.31.6-1.01.8-1.4-1.30.71.9
Progressive ratio test 1 inactive lever presses0.61.72.5-1.41.51.3-1.61.2-1.0-1.21.40.8
Progressive ratio test 2 active lever presses1.42.03.0-1.61.71.5-1.71.3-0.7-1.31.70.8
Progressive ratio test 2 breakpoint1.72.23.3-1.71.71.6-1.81.3-0.8-1.41.80.8
Progressive ratio test 2 inactive lever presses0.10.20.7-0.40.60.3-0.70.10.4-0.20.8-0.3
Incentive Sensitization - Responses0.61.74.0-1.21.61.2-1.90.8-0.4-1.32.0-0.0
Incentive Sensitization - Breakpoint0.71.64.0-1.11.51.1-1.90.7-0.4-1.22.0-0.2
Sum of active levers in priming session hrs 5-60.40.41.00.5-0.7-0.50.9-0.3-0.10.9-1.00.1
Progressive ratio0.72.25.11.4-1.1-1.30.9-1.72.31.4-0.4-1.9
Food seeking constrained by brief footshock4.45.59.42.4-2.8-2.42.9-1.91.42.4-3.1-1.0
Seeking ratio, punishment vs. effort0.40.82.50.7-1.1-0.81.2-0.3-0.50.7-1.60.4
Retroperitoneal fat weight0.00.20.8-0.00.50.3-0.6-0.10.2-0.30.9-0.5
Reaction time number correct1.86.58.3-2.92.72.8-2.72.8-2.4-2.12.12.4
Reaction time mean minus median0.00.10.20.3-0.0-0.2-0.3-0.30.4-0.10.2-0.5
Reaction time mean minus median AUC0.10.51.3-0.40.80.6-1.10.4-0.2-0.81.1-0.1
Reaction time num false alarms3.45.77.5-2.52.62.5-2.72.2-2.2-2.62.51.6
Reaction time num false alarms AUC2.14.75.9-2.32.32.2-2.42.1-2.1-2.32.21.5
Reaction time trials correct on left1.86.58.3-2.92.72.8-2.72.8-2.4-2.12.12.4
Reaction time trials on left1.96.58.2-2.92.72.8-2.72.8-2.4-2.12.12.4
Reaction time mean0.40.81.91.4-1.0-1.00.6-0.90.80.5-0.9-0.8
Reaction time mean AUC0.20.61.51.2-0.8-0.80.5-0.80.70.4-0.7-0.7
Median of all reaction times0.71.12.51.6-1.2-1.10.9-1.00.80.7-1.2-0.8
Reaction time omissions0.10.20.40.20.20.3-0.40.5-0.7-0.4-0.20.6
Reaction time false alarm rate0.20.20.5-0.30.50.3-0.60.2-0.3-0.70.7-0.1
Reaction time premature initiation rate0.30.50.80.8-0.9-0.70.9-0.60.20.6-0.9-0.3
Reaction time premature initiations0.20.51.1-0.60.60.7-0.50.9-1.1-0.50.20.9
Std. dev. reaction times0.00.20.40.6-0.3-0.40.0-0.40.60.1-0.1-0.5
Reaction time trials completed1.96.58.2-2.92.72.8-2.72.8-2.4-2.12.12.4
Reaction time trials AUC2.38.010.0-3.23.03.1-3.03.1-2.7-2.42.32.7
Run reversals in cocaine runway, females0.40.41.30.5-0.3-0.50.1-0.81.10.40.2-1.1
Run reversals in cocaine runway, males0.50.61.3-0.50.60.7-0.50.9-1.2-0.70.21.0
Latency to leave start box in cocaine runway0.30.41.4-0.40.70.6-0.90.00.2-0.21.2-0.6
Latency to leave start box in cocaine runway, F0.60.71.1-0.91.01.0-0.90.7-0.5-0.61.10.4
Latency to leave start box in cocaine runway, M0.40.41.30.20.2-0.1-0.6-0.50.70.10.8-1.1
Std. dev. time between licks in bursts0.00.10.1-0.30.20.3-0.20.3-0.3-0.20.10.3
Total sessions with >9 infusions3.03.84.8-2.21.92.1-1.82.1-2.0-1.81.42.0
Short access day 1 total inactive lever presses0.30.71.6-0.71.00.7-1.10.4-0.6-0.71.3-0.1
Short access day 10 total inactive lever presses0.21.12.01.2-1.0-1.20.7-1.30.80.9-0.5-1.4
Short access day 1 total infusions1.12.13.2-1.61.41.6-1.21.6-1.8-1.30.91.5
Short access day 10 total infusions2.33.85.0-2.22.02.2-1.82.2-1.9-1.71.32.1
Short access total infusions1.62.22.9-1.71.51.6-1.31.7-1.6-1.20.91.7
Short access day 1 locomotion2.23.65.2-2.01.92.0-1.82.0-2.3-1.71.41.8
Short access day 10 total locomotion0.10.52.1-0.1-0.00.2-0.10.6-1.5-0.5-0.51.0
Short access total locomotion0.91.33.7-1.00.61.0-0.41.4-1.6-0.9-0.31.9
One hour access (0.3 mA shock)0.20.20.7-0.20.50.2-0.8-0.00.1-0.10.8-0.5
Compulsive drug intake0.30.40.8-0.60.60.6-0.40.7-0.6-0.90.30.7
One hour access (shock baseline)0.51.22.4-1.11.31.1-1.50.8-0.8-0.81.50.3
Social response proportion1.41.82.6-1.21.41.4-1.61.4-1.2-1.51.21.1
Social responses0.91.11.6-0.91.21.2-1.31.1-0.8-1.21.00.8
Social time2.64.16.82.1-1.9-2.11.8-2.22.61.9-1.3-2.1
Soleus weight0.41.14.3-0.61.10.7-1.3-0.10.5-0.52.1-1.2
Bone: stiffness0.61.12.2-1.21.31.0-1.30.8-0.6-1.01.50.3
Tibialis anterior weight2.910.015.8-3.23.63.4-3.62.7-2.4-3.24.01.5
Time to tail flick, vehicle, before self-admin2.32.86.6-1.71.31.8-0.82.1-1.7-1.60.32.6
Time to tail flick, vehicle, after self-admin0.20.51.6-0.10.60.1-0.9-0.40.50.01.3-1.1
Time to tail flick, test, before self-admin0.80.93.20.8-1.1-0.61.4-0.1-0.40.5-1.80.7
Time to tail flick, test, after self-admin0.30.30.90.5-0.5-0.50.5-0.40.90.7-0.6-0.2
Delta time to tail flick, vehicle, before/after SA0.30.31.20.30.0-0.4-0.3-0.60.50.30.6-1.1
Delta time to tail flick, test, before/after SA0.60.81.7-1.01.10.9-1.20.60.1-0.61.30.1
Tibia length0.30.91.7-0.90.70.8-0.61.0-1.3-1.20.21.2
Ambulatory time before self-admin0.00.00.10.00.0-0.1-0.1-0.1-0.1-0.20.2-0.2
Ambulatory time after self-admin0.30.50.80.7-0.8-0.70.9-0.60.50.7-0.8-0.4
Bone: tissue strength0.70.71.50.9-1.0-0.90.9-0.50.80.7-1.2-0.1
Total heroin consumption0.00.10.40.1-0.1-0.10.1-0.1-0.60.1-0.1-0.1
Bone: trabecular number0.00.00.10.1-0.10.0-0.1-0.1-0.4-0.00.1-0.2
Bone: trabecular spacing0.00.00.0-0.10.1-0.10.00.20.2-0.1-0.00.2
Bone: trabecular thickness1.52.03.1-1.41.41.5-1.51.4-1.8-1.51.21.1
Bone: trabecular tissue density0.30.50.9-0.70.80.7-0.90.5-0.5-1.00.90.3
Water consumed over 24 hours0.30.51.70.3-0.5-0.10.40.4-1.3-0.1-1.11.0
Number of responses in last shaping day2.53.24.5-1.91.91.8-1.91.7-2.1-1.71.71.3