Clns1a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Clns1a 0.08 0.05 2.6e-07 0.06 0.07 0.06 0.06 1.7e-07 4.5e-08 1.0e-06 3.2e-07
2 OFC mRNA stability Clns1a 0.17 0.11 5.1e-03 0.05 -0 -0.01 0 2.6e-02 3.5e-01 6.4e-01 2.7e-01
3 LHb mRNA stability Clns1a 0.19 0.12 8.7e-03 0.07 0.05 0.01 0.05 8.6e-03 2.2e-02 2.2e-01 2.4e-02
4 RMTg mRNA stability Clns1a 0.14 0.1 4.4e-03 0.06 0.05 0.09 0.05 9.8e-03 1.8e-02 2.8e-03 1.5e-02
5 Adipose isoform ratio NM_031719.2 0.06 0.04 7.7e-04 0.02 0.01 0.01 0.01 2.2e-03 3.2e-02 2.6e-02 2.6e-02
6 Adipose isoform ratio XM_006229792.3 0.06 0.05 7.1e-04 0.02 0.01 0.01 0.01 1.9e-03 3.2e-02 3.0e-02 2.1e-02
7 NAcc isoform ratio XM_006229792.3 0.02 0.01 4.8e-03 0.02 0.02 0.02 0.02 3.3e-04 1.1e-03 6.4e-04 6.1e-04
8 Brain mRNA stability Clns1a 0.3 0.11 0.0e+00 0.31 0.33 0.32 0.32 2.3e-29 1.9e-31 9.1e-31 2.0e-30
9 PL isoform ratio XM_006229792.3 0.04 0.03 7.4e-04 0.02 0.02 0.01 0.02 3.5e-03 1.7e-03 1.2e-02 7.0e-03
10 PL isoform ratio NM_031719.2 0.04 0.03 2.9e-04 0.03 0.03 0.02 0.02 9.1e-04 5.5e-04 2.9e-03 1.4e-03
11 NAcc mRNA stability Clns1a 0.05 0.03 1.3e-06 0.06 0.04 0.05 0.05 2.6e-09 3.2e-07 7.7e-08 2.9e-08
12 BLA mRNA stability Clns1a 0.17 0.1 3.6e-05 0.03 0.07 0.02 0.04 7.1e-03 1.7e-04 3.4e-02 3.0e-03
13 IL mRNA stability Clns1a 0.3 0.17 3.3e-03 0 0.01 0 0.01 3.2e-01 1.5e-01 3.1e-01 1.6e-01
14 Adipose alternative TSS XM_006229792.3 0.08 0.06 7.4e-06 0.02 0.02 0.02 0.02 2.8e-03 1.9e-03 1.9e-03 5.4e-03
15 Adipose alternative TSS NM_031719.2 0.07 0.05 2.2e-05 0.01 0.02 0.02 0.01 7.0e-03 4.2e-03 3.6e-03 1.4e-02
16 NAcc gene expression Clns1a 0.05 0.03 1.7e-06 0.04 0.04 0.03 0.04 1.3e-06 5.4e-07 5.1e-06 1.2e-06
17 Liver mRNA stability Clns1a 0.06 0.06 6.4e-03 -0 0 0.01 -0 4.5e-01 1.2e-01 2.6e-02 4.6e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.00.10.20.00.10.1-0.30.3-0.30.1-0.1-0.10.10.0-0.1-0.2-0.50.50.4-0.4
Area under the delay curve1.01.12.2-1.1-0.9-0.90.61.2-1.2-1.2-1.1-1.11.1-1.5-1.3-1.2-1.00.90.8-0.8
BMI with tail2.910.013.42.93.43.40.9-3.33.33.53.33.3-3.33.52.62.93.6-3.7-3.62.0
BMI without tail3.911.917.83.03.43.40.9-3.63.63.83.63.6-3.63.32.93.44.2-4.2-4.12.7
Body weight3.816.822.53.64.04.02.0-4.34.34.64.34.2-4.24.13.64.14.7-4.7-4.53.5
Weight adjusted by age0.30.51.40.40.60.61.2-0.60.60.60.60.6-0.70.40.20.31.0-1.1-1.20.1
Bone surface0.71.32.8-1.3-1.0-1.01.71.4-1.4-0.9-1.1-1.11.1-1.0-1.4-1.2-0.70.60.3-0.8
Bone volume0.20.42.6-0.7-0.3-0.31.60.8-0.8-0.4-0.5-0.50.5-0.4-0.9-0.8-0.20.1-0.2-0.4
Breakpoint value in progressive ratio session0.10.20.80.00.30.30.20.2-0.2-0.5-0.2-0.20.30.1-0.1-0.3-0.60.70.8-0.9
Number of licking bursts1.62.75.42.12.32.3-1.0-1.51.51.81.81.8-1.72.21.51.31.1-1.0-0.80.3
Context. condit. distance diff. score3.34.05.6-2.2-1.7-1.72.22.3-2.3-1.8-2.1-2.12.1-1.9-2.4-2.3-1.81.61.3-1.9
Locomotion velocity, session 11.71.82.3-1.2-1.3-1.3-0.31.4-1.4-1.4-1.5-1.41.4-1.4-1.3-1.4-1.51.51.4-1.2
Locomotion distance, session 10.60.81.1-1.0-1.0-1.0-0.81.0-1.0-0.6-1.0-0.90.9-0.9-0.7-0.7-0.90.80.7-0.9
Locomotion velocity, session 20.40.51.0-0.8-0.8-0.81.00.6-0.6-1.0-0.8-0.70.7-1.0-0.8-0.7-0.30.20.2-0.3
Locomotion distance, session 20.10.11.0-0.1-0.4-0.4-0.3-0.20.2-0.10.0-0.0-0.0-0.20.30.40.2-0.2-0.11.0
Locomotion velocity, session 30.40.41.3-0.7-0.7-0.71.10.7-0.7-0.6-0.7-0.70.7-0.8-0.7-0.6-0.50.50.4-0.3
Locomotion distance, session 32.62.93.7-1.8-1.5-1.50.61.9-1.9-1.6-1.9-1.91.9-1.5-1.9-1.9-1.71.61.4-1.6
Stereotopy head waving bouts, day 32.73.25.81.91.31.3-0.0-2.22.21.92.01.9-1.91.62.42.31.7-1.5-1.21.6
Stereotopy head waving duration, day 30.20.32.50.1-0.4-0.40.5-0.40.40.20.20.1-0.20.00.70.80.2-0.10.11.6
Locomotion velocity, session 70.50.51.1-0.5-0.2-0.20.50.8-0.8-0.9-0.7-0.60.6-0.8-1.0-1.1-0.70.70.5-0.9
Locomotion distance, session 70.40.51.9-0.50.20.20.70.9-0.9-0.4-0.6-0.50.6-0.4-1.3-1.2-0.50.30.1-1.4
Stereotopy head waving bouts, day 70.91.02.7-1.1-1.7-1.70.80.7-0.7-1.2-1.0-1.11.0-1.3-0.3-0.4-0.80.91.00.0
Stereotopy head waving duration, day 70.60.72.2-1.0-1.5-1.51.40.5-0.5-1.0-0.8-0.80.8-1.0-0.2-0.1-0.40.40.50.5
Locomotion velocity, session 87.18.512.4-3.1-2.5-2.52.43.5-3.5-3.1-3.1-3.13.1-3.1-3.5-3.4-2.72.52.1-1.9
Locomotion distance, session 81.62.33.2-1.8-1.6-1.61.71.7-1.7-1.4-1.6-1.61.6-1.6-1.6-1.5-1.21.10.9-0.8
Degree of sensitization distance1.81.93.11.31.51.50.3-1.31.31.51.51.5-1.51.31.01.21.6-1.7-1.80.6
Degree of sensitization stereotypy3.03.35.9-2.1-2.4-2.41.11.8-1.8-2.0-2.0-2.02.0-2.0-1.4-1.4-1.61.51.5-0.9
Conditioned locomotion0.20.20.5-0.3-0.5-0.5-0.30.3-0.3-0.4-0.5-0.50.5-0.4-0.2-0.3-0.50.60.70.5
Cocaine response after cond. corrected0.20.21.80.20.70.70.00.1-0.1-0.10.10.2-0.10.4-0.6-0.60.1-0.1-0.3-1.3
Cocaine response after cond. not corrected0.20.32.5-0.20.10.1-0.00.5-0.5-0.4-0.3-0.30.3-0.0-0.6-0.7-0.40.40.2-1.6
Cocaine response before conditioning0.40.41.4-0.5-1.2-1.2-0.30.3-0.3-0.4-0.4-0.60.5-0.90.40.3-0.80.90.9-0.1
Saline control response0.20.22.3-0.4-0.4-0.40.10.0-0.00.3-0.0-0.10.00.30.30.50.4-0.5-0.51.5
Bone: connectivity density0.81.31.9-1.0-0.9-0.90.11.3-1.3-1.0-1.1-1.11.1-1.1-1.0-1.2-1.41.31.2-1.4
Bone: cortical apparent density0.20.30.90.71.01.0-0.6-0.50.50.40.50.5-0.50.80.30.20.3-0.2-0.10.0
Bone: cortical area0.20.41.10.20.90.90.7-0.10.10.80.50.5-0.50.8-0.10.10.7-0.8-1.0-0.4
Bone: cortical porosity0.20.20.8-0.4-0.9-0.9-0.40.2-0.2-0.3-0.4-0.40.4-0.70.20.1-0.50.50.6-0.0
Bone: cortical porosity0.20.31.1-0.4-1.0-1.0-0.30.2-0.2-0.3-0.3-0.40.3-0.70.30.2-0.40.50.60.1
Bone: cortical thickness0.30.51.40.81.21.2-0.9-0.30.31.00.70.7-0.71.00.30.20.3-0.3-0.5-0.8
Bone: cortical thickness0.30.43.0-0.40.10.1-0.10.7-0.7-0.1-0.4-0.30.3-0.0-0.9-0.8-0.30.2-0.1-1.7
Bone: cortical tissue density0.20.20.70.60.80.8-0.6-0.40.40.30.40.4-0.40.70.30.20.2-0.10.0-0.0
Condit. Reinf. active minus inactive responses1.11.22.10.91.31.3-0.4-0.90.91.41.11.1-1.11.40.60.81.3-1.4-1.40.6
Condit. Reinf. active-inactive response ratio1.01.11.80.81.01.00.0-1.01.01.31.01.0-1.01.20.81.01.3-1.3-1.31.0
Condit. Reinf. active responses0.91.11.81.01.21.2-0.4-0.90.91.41.01.1-1.11.20.70.91.1-1.1-1.20.6
Condit. Reinf. inactive responses0.00.00.10.20.20.20.2-0.10.10.20.20.2-0.20.10.10.10.1-0.1-0.1-0.1
Incentive salience index mean0.30.41.20.50.80.80.1-0.40.40.80.60.6-0.60.70.00.20.9-1.0-1.10.1
Condit. Reinf. lever presses0.20.31.0-0.6-0.3-0.30.60.7-0.7-0.6-0.6-0.50.5-0.6-1.0-0.9-0.40.30.1-0.6
Condit. Reinf. active minus inactive responses0.70.94.5-1.4-1.1-1.12.10.9-0.9-0.5-0.7-0.80.7-0.7-1.0-0.50.3-0.5-0.90.3
Condit. Reinf. active-inactive response ratio0.50.51.5-0.9-0.4-0.41.11.0-1.0-0.8-0.7-0.70.7-0.3-1.2-1.0-0.20.0-0.3-0.6
Condit. Reinf. active responses0.91.26.8-1.5-1.2-1.22.60.7-0.7-0.2-0.6-0.60.5-0.9-0.8-0.10.7-1.0-1.41.1
Condit. Reinf. inactive responses0.91.14.9-0.4-0.9-0.92.0-0.50.50.60.30.2-0.3-0.60.61.11.3-1.4-1.42.2
Condit. Reinf. lever presses5.17.014.8-3.9-3.6-3.63.62.8-2.8-2.4-2.8-2.92.8-2.7-2.5-1.8-1.20.90.51.0
Condit. Reinf. lever reinforcers received1.01.47.7-1.8-1.4-1.42.81.0-1.0-0.4-0.8-0.90.8-1.0-1.0-0.30.5-0.8-1.20.8
Conditioned reinforcement - actives1.22.04.9-1.5-1.4-1.42.21.4-1.4-1.4-1.3-1.41.4-1.5-1.3-1.3-1.11.00.9-1.5
Conditioned reinforcement - inactives0.30.41.1-0.4-0.9-0.9-0.40.4-0.4-0.6-0.5-0.60.6-0.7-0.2-0.4-0.80.91.10.2
Conditioned locomotion3.64.76.7-2.3-2.6-2.61.62.3-2.3-2.3-2.2-2.32.2-2.4-1.9-1.9-2.12.01.9-1.7
Patch foraging indifference point 0 sec0.51.02.8-1.5-1.7-1.71.40.8-0.8-0.6-0.9-1.01.0-0.7-0.5-0.2-0.20.10.01.1
Patch foraging indifference point AUC0.10.10.4-0.00.30.30.70.1-0.1-0.10.00.1-0.10.3-0.3-0.20.2-0.3-0.5-0.4
Delay disc. indifference point, 0s delay0.10.20.3-0.6-0.6-0.60.40.3-0.3-0.4-0.3-0.30.3-0.5-0.4-0.20.1-0.2-0.4-0.6
Delay disc. indifference point, 16s delay1.21.34.0-1.0-1.0-1.0-0.21.2-1.2-1.3-1.2-1.11.2-2.0-1.2-1.2-1.21.21.1-0.2
Delay disc. indifference point, 2s delay0.70.82.2-1.1-1.2-1.21.50.9-0.9-0.9-0.9-0.90.9-0.8-0.8-0.7-0.50.50.4-0.1
Delay disc. indifference point, 24s delay0.10.10.30.00.50.50.10.3-0.3-0.4-0.2-0.20.2-0.4-0.5-0.6-0.40.50.5-0.1
Delay disc. indifference point, 4s delay0.70.74.0-1.0-0.7-0.72.00.8-0.8-0.8-0.7-0.70.7-0.9-1.1-0.9-0.0-0.1-0.3-0.1
Delay disc. indifference point, 8s delay1.01.22.0-1.1-0.9-0.90.31.2-1.2-1.2-1.2-1.11.1-1.4-1.3-1.3-1.01.00.8-0.9
Indifference point function ln k0.71.32.9-1.3-1.7-1.70.50.9-0.9-1.0-1.2-1.21.2-1.6-0.5-0.5-1.11.11.20.5
Indifference point function log k0.71.32.9-1.3-1.7-1.70.50.9-0.9-1.0-1.2-1.21.2-1.6-0.5-0.5-1.11.11.20.5
Patch foraging total patch changes 0 sec0.50.92.4-1.5-1.5-1.51.41.0-1.0-0.6-1.0-1.11.0-0.6-0.7-0.3-0.30.20.10.8
Patch foraging total patch changes 12 sec0.30.43.2-0.00.20.21.8-0.00.00.40.30.3-0.30.70.00.30.7-0.8-1.0-0.1
Patch foraging total patch changes 18 sec0.20.33.1-0.6-0.3-0.31.80.3-0.3-0.3-0.2-0.20.20.2-0.5-0.10.5-0.7-0.90.2
Patch foraging total patch changes 24 sec0.10.21.00.00.20.20.4-0.20.20.30.30.3-0.30.90.10.30.7-0.8-1.0-0.3
Patch foraging total patch changes 6 sec0.10.20.5-0.7-0.6-0.60.40.4-0.4-0.2-0.4-0.50.5-0.1-0.10.0-0.20.20.30.7
Patch foraging time to switch 0 sec0.81.63.61.91.51.5-1.9-1.41.41.21.41.4-1.41.01.51.10.5-0.3-0.1-0.2
Patch foraging water rate 0 sec0.81.83.8-1.9-1.6-1.62.01.5-1.5-1.2-1.5-1.51.5-0.9-1.4-1.0-0.70.50.3-0.2
Patch foraging water rate 12 sec0.71.63.0-1.7-1.7-1.70.61.3-1.3-1.3-1.5-1.51.5-1.0-1.2-1.0-0.90.80.80.6
Patch foraging water rate 18 sec0.20.30.8-0.9-0.6-0.60.60.3-0.3-0.4-0.7-0.70.7-0.3-0.8-0.60.0-0.1-0.00.6
Patch foraging water rate 24 sec1.72.43.4-1.8-1.7-1.70.61.5-1.5-1.8-1.8-1.81.8-1.2-1.6-1.6-1.41.41.50.2
Patch foraging water rate 6 sec0.91.21.8-1.3-1.3-1.30.31.2-1.2-1.1-1.3-1.31.3-0.9-1.0-1.0-1.11.01.0-0.1
Seeking ratio, delayed vs. immediate footshock0.30.32.20.60.70.7-1.0-0.50.50.10.20.3-0.3-0.4-0.3-0.50.00.0-0.0-1.5
Distance traveled before self-admin0.10.20.40.50.60.6-0.1-0.50.50.20.40.4-0.40.60.30.30.3-0.2-0.10.1
Distance traveled after self-admin0.30.42.10.70.10.1-1.4-0.60.60.50.40.3-0.30.51.00.7-0.30.40.70.1
Extensor digitorum longus weight0.31.32.40.91.51.51.1-0.90.91.21.11.1-1.11.10.30.51.4-1.5-1.51.2
Bone: elastic displacement0.20.21.30.20.50.5-1.10.2-0.2-0.1-0.1-0.10.10.0-0.3-0.5-0.50.50.6-0.6
Bone: elastic work0.71.03.6-0.2-0.0-0.0-1.90.9-0.9-0.7-0.7-0.70.7-0.6-0.7-1.0-1.41.41.4-1.2
Bone: endosteal estimation0.20.54.9-0.30.00.02.20.0-0.00.10.10.1-0.10.1-0.4-0.10.9-1.1-1.30.5
Bone: endosteal perimeter0.51.18.9-1.2-0.8-0.83.00.7-0.7-0.8-0.8-0.70.7-0.8-1.2-0.80.3-0.5-0.70.5
Epididymis fat weight1.65.38.42.42.92.90.4-2.62.62.52.52.4-2.42.52.02.02.4-2.3-2.00.9
Delta time in closed arm before/after self-admin0.30.20.80.30.90.9-0.9-0.10.10.00.10.3-0.20.3-0.5-0.40.4-0.4-0.50.8
Delta time in open arm before/after self-admin0.60.65.6-1.0-0.6-0.62.40.6-0.6-0.4-0.5-0.60.6-0.3-0.7-0.40.0-0.2-0.3-0.0
Diff in mean of infusions in LGA sessions1.41.74.21.72.02.0-1.5-1.21.21.41.41.3-1.21.61.41.00.4-0.20.20.5
Delay discount exponential model param1.01.12.01.10.90.9-0.6-1.11.11.21.11.1-1.11.41.21.21.0-0.9-0.80.7
Extinction: sum of active levers before priming0.20.21.6-0.10.30.31.3-0.20.2-0.00.10.1-0.10.2-0.10.10.5-0.5-0.50.5
Active lever presses in extinction session 61.41.44.3-1.3-2.1-2.1-0.40.8-0.8-1.1-1.2-1.31.3-1.0-0.1-0.2-1.31.31.6-0.1
Bone: final force0.30.51.7-0.50.00.0-0.11.0-1.0-0.1-0.5-0.60.6-0.1-0.8-0.9-0.90.80.5-1.3
Bone: final moment0.20.41.2-0.50.00.0-0.00.9-0.9-0.0-0.4-0.50.5-0.0-0.7-0.7-0.70.70.4-1.1
Food consumed during 24 hour testing period1.92.75.8-1.9-2.4-2.42.01.4-1.4-1.8-1.7-1.71.7-1.8-1.1-1.0-1.21.21.20.3
Glucose0.20.32.5-0.30.30.31.60.4-0.4-0.0-0.1-0.20.20.1-0.7-0.60.1-0.2-0.3-0.2
Heart weight0.10.10.3-0.6-0.3-0.3-0.20.2-0.2-0.2-0.4-0.40.4-0.4-0.4-0.2-0.10.00.10.2
Delay discount hyperbolic model param0.91.01.71.10.90.9-1.0-1.11.11.11.11.0-1.01.31.21.20.8-0.7-0.60.7
Intermittent access intake day 1-15 change1.22.55.5-1.8-2.3-2.30.91.5-1.5-1.7-1.6-1.71.7-2.1-1.2-1.2-1.41.31.3-0.6
Intermittent access intake escalation1.63.36.1-2.0-2.5-2.51.21.7-1.7-2.0-1.8-1.91.9-2.3-1.5-1.5-1.51.51.5-1.0
Intermittent access intake escalation 21.11.33.1-1.2-1.8-1.81.50.9-0.9-1.2-1.0-1.11.0-1.5-0.8-0.8-0.80.70.7-0.8
Intermitt. access day 1 inactive lever presses0.10.33.20.7-0.1-0.1-1.8-0.30.30.40.30.3-0.30.20.40.1-0.30.50.5-0.3
Intermitt. access day 15 inactive lever presses0.30.64.41.00.30.3-2.1-0.80.80.60.60.6-0.60.50.80.50.00.10.40.4
Intermitt. access escalation Index0.20.30.8-0.30.00.0-0.30.6-0.6-0.3-0.5-0.50.5-0.4-0.4-0.5-0.80.80.9-0.3
Intermittent access day 1 total infusions0.81.22.4-1.3-1.1-1.11.61.2-1.2-1.1-1.1-1.21.2-1.2-1.3-1.2-0.80.70.7-0.3
Intermittent access day 15 total infusions3.55.27.8-2.5-2.8-2.82.42.3-2.3-2.4-2.3-2.42.4-2.7-2.2-2.1-1.91.81.7-1.2
Intermittent access terminal intake (last 3 days)2.22.96.5-1.9-2.4-2.42.61.5-1.5-1.7-1.5-1.71.6-2.2-1.5-1.4-1.21.11.0-0.5
Intermittent access total infusions1.61.88.4-1.4-1.5-1.52.91.2-1.2-1.3-1.1-1.31.2-1.5-1.4-1.3-0.70.60.6-0.7
Intermittent access day 1 locomotion0.91.11.6-1.0-0.9-0.90.91.2-1.2-1.0-1.0-1.11.1-1.1-1.0-1.1-1.21.11.1-0.5
Intermittent access day 15 total locomotion1.01.84.2-1.5-2.1-2.11.01.2-1.2-1.3-1.3-1.41.4-1.8-0.8-0.8-1.21.11.10.0
Intermittent access total locomotion0.81.05.6-1.0-1.2-1.22.40.8-0.8-0.8-0.7-0.90.9-1.1-0.7-0.7-0.60.60.60.0
Intermittent access standard deviation0.30.62.90.3-0.2-0.21.7-0.80.80.40.60.6-0.60.20.40.61.1-1.1-1.00.7
Left kidney weight1.36.39.82.01.81.81.3-2.82.82.72.62.5-2.61.72.42.73.1-3.1-3.02.6
Right kidney weight1.46.610.82.01.71.71.6-2.82.82.62.62.6-2.61.92.42.83.3-3.3-3.22.8
Cocaine induced anxiety1.01.52.41.61.31.3-1.5-1.21.21.41.41.4-1.31.51.31.10.8-0.7-0.60.6
Post-drug Anxiety0.40.51.80.90.80.8-1.3-0.60.60.60.60.7-0.70.90.50.40.4-0.3-0.20.6
Baseline Anxiety0.81.01.8-1.2-1.0-1.00.50.9-0.9-1.2-1.2-1.11.1-1.2-1.3-1.2-0.60.50.50.1
Tail length1.76.811.91.92.12.12.2-2.72.72.62.62.5-2.61.82.02.63.4-3.5-3.43.0
Length with tail2.19.313.52.42.52.52.3-3.23.23.43.23.0-3.12.62.73.23.6-3.7-3.53.2
Length without tail0.92.84.51.71.51.50.4-2.02.02.11.91.7-1.72.02.02.01.5-1.4-1.11.5
Times rat made contact with spout1.21.41.61.21.01.01.0-1.31.30.91.31.2-1.21.21.21.21.2-1.2-1.01.2
Lifetime Intake1.92.36.0-1.7-1.8-1.82.51.5-1.5-1.5-1.5-1.51.5-1.8-1.6-1.5-1.00.90.8-1.0
Liver weight, left1.32.13.31.31.51.51.1-1.51.51.61.61.5-1.51.21.11.21.8-1.8-1.70.4
Liver weight, right5.08.811.53.03.03.01.0-3.23.23.23.33.3-3.32.72.72.93.4-3.4-3.21.3
Locomotor activity0.60.95.30.4-0.6-0.6-0.4-0.80.80.50.60.6-0.70.11.31.50.9-0.9-0.72.3
Locomotor testing distance0.71.23.70.4-0.0-0.00.4-0.90.90.80.80.9-1.00.71.11.41.5-1.6-1.71.9
Locomotor testing rearing1.83.75.91.61.51.50.4-1.91.91.91.92.0-2.02.11.82.12.4-2.4-2.41.8
Locomotion in novel chamber2.12.64.4-1.7-1.6-1.61.32.1-2.1-1.4-1.5-1.71.7-1.6-1.3-1.4-1.91.81.5-1.0
Locomotion in novel chamber post-restriction3.25.27.2-2.7-2.5-2.51.52.6-2.6-2.1-2.5-2.62.5-2.3-2.2-2.1-2.22.12.0-0.9
Fecal boli incidents, locomotor time 12.33.34.7-1.8-1.9-1.9-1.42.1-2.1-1.8-1.9-1.81.8-1.7-1.9-1.9-1.71.61.2-2.2
Change in fecal boli incidents, locomotor task0.70.71.61.00.60.6-0.7-1.11.11.00.90.8-0.80.31.21.10.5-0.4-0.11.2
Time >=10cm from walls, locomotor time 12.02.13.0-1.7-1.4-1.40.51.7-1.7-1.5-1.7-1.71.7-0.9-1.3-1.3-1.61.51.4-0.7
Bouts of movement, locomotor time 10.40.50.9-0.8-0.9-0.9-0.50.7-0.7-0.7-0.7-0.70.7-0.5-0.8-0.7-0.50.40.30.4
Total resting periods, locomotor time 10.80.81.2-0.9-1.1-1.1-0.91.0-1.0-1.0-0.9-0.91.0-0.7-0.9-0.9-0.90.90.80.1
Rest time, locomotor task time 11.11.42.0-1.0-0.9-0.9-0.81.3-1.3-1.3-1.3-1.21.2-1.1-1.2-1.3-1.41.41.3-0.8
Distance moved, locomotor task time 10.60.92.70.60.60.61.6-0.80.80.80.90.9-0.90.80.50.71.3-1.3-1.50.6
Vertical activity count, locomotor time 10.20.52.40.30.30.31.5-0.50.50.50.60.6-0.60.40.30.51.0-1.0-1.10.4
Time >=10cm from walls, locomotor time 20.20.30.8-0.8-0.4-0.40.90.6-0.6-0.5-0.6-0.60.50.2-0.7-0.6-0.20.0-0.2-0.5
Bouts of movement, locomotor time 20.30.51.6-0.3-1.2-1.21.1-0.10.10.30.1-0.0-0.0-1.30.20.40.4-0.5-0.41.1
Total resting periods, locomotor time 20.20.31.6-0.3-1.1-1.10.80.0-0.00.2-0.0-0.10.1-1.30.10.20.2-0.3-0.20.8
Rest time, locomotor task time 20.40.51.80.81.01.0-1.4-0.40.40.50.50.5-0.50.70.60.3-0.10.30.4-1.0
Distance moved, locomotor task time 20.50.66.3-0.7-0.6-0.62.50.3-0.3-0.4-0.3-0.30.2-0.3-0.7-0.30.5-0.7-0.90.1
Vertical activity count, locomotor time 20.40.54.9-0.2-0.5-0.52.2-0.20.20.10.10.2-0.20.2-0.3-0.00.8-0.9-1.10.4
Light reinforcement 11.02.54.41.81.91.9-1.8-1.71.72.11.71.6-1.61.71.51.41.2-1.1-1.00.2
Light reinforcement 20.10.21.20.20.10.1-1.1-0.20.20.60.20.2-0.20.40.60.5-0.00.10.1-0.3
Bone: marrow area0.20.54.4-0.20.10.12.1-0.10.10.20.20.2-0.20.2-0.30.00.9-1.1-1.30.5
Bone: maximum diameter0.30.54.7-0.8-0.3-0.32.20.5-0.5-0.0-0.3-0.30.3-0.1-0.7-0.30.4-0.6-0.80.4
Bone: maximum force0.61.12.4-0.9-0.3-0.3-0.21.6-1.6-0.5-0.9-1.01.0-0.5-1.2-1.2-1.41.30.9-1.5
Bone: maximum moment0.50.92.1-0.9-0.3-0.3-0.11.5-1.5-0.4-0.9-0.90.9-0.4-1.1-1.1-1.21.10.8-1.3
Mean time between licks in bursts0.40.94.7-0.3-0.6-0.62.2-0.30.30.50.30.3-0.4-0.70.20.61.3-1.5-1.61.2
Mean num. licks in bursts1.21.83.6-1.7-1.9-1.91.61.2-1.2-1.5-1.4-1.41.4-1.8-1.3-1.1-0.70.60.50.1
Cd content in liver0.91.02.30.91.51.50.5-0.80.81.20.91.0-1.01.30.40.61.0-1.0-1.1-0.0
Co content in liver0.10.20.7-0.3-0.2-0.20.80.0-0.00.1-0.10.0-0.1-0.0-0.4-0.10.5-0.6-0.80.5
Cu content in liver1.82.14.21.11.11.10.8-1.61.61.11.41.5-1.50.91.11.42.0-2.0-2.01.7
Fe content in liver0.00.00.2-0.10.10.1-0.10.1-0.1-0.2-0.0-0.10.10.1-0.2-0.3-0.10.1-0.0-0.4
K content in liver0.30.30.90.70.10.10.4-0.80.80.20.60.6-0.6-0.50.90.90.5-0.4-0.30.1
Mg content in liver0.10.10.8-0.1-0.6-0.60.4-0.10.1-0.2-0.1-0.10.0-0.90.30.30.00.00.10.1
Mn content in liver0.30.41.30.0-0.3-0.3-1.10.3-0.3-0.2-0.3-0.30.4-0.40.0-0.3-0.91.01.1-0.9
Na content in liver0.50.52.3-0.5-1.3-1.30.90.1-0.1-0.8-0.4-0.40.4-1.50.30.2-0.40.50.5-0.7
Rb content in liver0.10.21.20.20.30.3-0.1-0.30.30.30.30.3-0.3-0.20.30.40.5-0.5-0.31.1
Se content in liver0.91.04.01.51.31.3-0.6-0.90.90.71.01.0-0.90.91.10.7-0.00.20.3-2.0
Sr content in liver0.60.50.8-0.8-0.6-0.60.30.9-0.9-0.7-0.8-0.80.8-0.4-0.9-0.9-0.80.70.6-0.9
Zn content in liver0.70.85.9-0.0-0.1-0.12.4-0.50.50.40.40.4-0.5-0.30.20.61.2-1.4-1.50.5
Bone: minimum diameter0.71.33.70.81.21.20.9-0.80.81.21.11.1-1.11.20.40.71.5-1.7-1.90.3
Time in familiar zone, hab. session 10.00.00.1-0.10.00.00.40.1-0.1-0.1-0.1-0.10.1-0.1-0.3-0.3-0.10.10.1-0.2
Time in novel zone, hab. session 10.60.60.70.80.80.8-0.6-0.80.80.80.80.8-0.80.80.80.80.8-0.8-0.80.7
Total zone transitions, hab. session 10.30.42.0-0.3-0.5-0.5-1.40.4-0.40.1-0.4-0.50.5-0.20.30.2-0.90.91.10.5
Total locomotion distance, hab. session 16.89.612.83.42.92.9-1.0-3.53.53.53.53.4-3.43.23.63.53.0-2.8-2.51.8
Locomotion velocity, hab. session 15.78.011.43.12.52.5-1.0-3.23.23.23.23.1-3.13.03.43.32.7-2.6-2.31.5
Time in familiar zone, hab. session 20.50.55.7-0.5-0.5-0.52.40.3-0.3-0.5-0.3-0.30.2-0.4-0.5-0.30.2-0.3-0.30.9
Time in novel zone, hab. session 20.20.22.3-0.10.10.1-1.50.2-0.2-0.1-0.2-0.20.2-0.1-0.3-0.3-0.20.20.2-1.2
Total zone transitions, hab. session 20.50.62.4-0.7-0.9-0.9-1.60.6-0.6-0.1-0.6-0.70.7-0.40.10.1-0.80.91.00.7
Total locomotion distance, hab. session 25.06.58.92.62.22.2-1.4-2.72.73.02.82.7-2.72.72.93.02.5-2.4-2.31.8
Locomotion velocity, hab. session 25.57.410.02.72.42.4-1.6-2.92.93.22.92.9-2.92.93.13.22.7-2.6-2.42.1
Novel to familiar place preference ratio0.10.10.50.00.00.0-0.7-0.20.20.40.10.0-0.10.20.40.40.1-0.00.10.3
Novelty place preference0.00.00.2-0.1-0.0-0.0-0.5-0.10.10.20.0-0.00.00.10.20.20.1-0.10.00.3
Time in novel zone, NPP test0.00.00.1-0.3-0.2-0.2-0.20.1-0.1-0.0-0.2-0.30.3-0.1-0.1-0.1-0.10.10.20.2
Total zone transitions, NPP test0.81.22.4-1.0-0.9-0.9-1.51.2-1.2-0.8-1.1-1.11.2-0.9-0.9-1.0-1.31.31.3-0.7
Total locomotion distance, NPP test3.54.76.32.42.32.3-1.4-2.32.32.52.42.4-2.42.42.22.22.1-2.0-2.00.1
Locomotion velocity, NPP test4.36.18.32.72.62.6-1.7-2.62.62.92.72.7-2.72.72.52.52.3-2.2-2.20.1
Intraocular pressure4.66.610.4-2.7-2.1-2.11.13.0-3.0-2.9-2.8-2.72.8-2.5-3.2-3.2-2.52.32.0-1.8
Delta distance traveled before/after self-admin0.30.41.3-0.2-1.1-1.1-1.00.0-0.00.2-0.2-0.30.2-0.50.60.5-0.50.50.70.8
Delta ambulatory time before/after self-admin0.40.51.2-0.4-1.1-1.1-1.10.3-0.3-0.0-0.5-0.50.5-0.50.30.2-0.80.80.90.7
Parametrial fat weight1.22.86.51.72.02.0-1.3-1.61.62.51.81.6-1.72.11.91.91.2-1.1-1.00.5
Pavlov. Cond. lever latency0.70.93.21.01.01.0-1.8-0.90.91.10.80.8-0.81.21.10.90.4-0.2-0.00.4
Pavlov. Cond. magazine entry latency0.40.53.5-0.9-0.8-0.81.90.6-0.6-0.5-0.5-0.50.4-0.7-0.6-0.30.1-0.3-0.50.3
Pavlov. Cond. change in total contacts0.80.82.8-0.9-0.8-0.81.70.9-0.9-1.0-0.7-0.70.7-0.9-1.1-1.0-0.40.2-0.1-1.2
Pavlov. Cond. index score0.50.64.1-0.8-0.8-0.82.00.6-0.6-0.8-0.5-0.50.4-0.9-0.8-0.50.1-0.3-0.6-0.1
Pavlov. Cond. latency score0.50.64.3-0.8-0.7-0.72.10.7-0.7-0.7-0.5-0.50.5-0.8-0.8-0.50.1-0.2-0.5-0.1
Pavlov. Cond. lever contacts0.30.42.0-0.6-0.6-0.61.40.6-0.6-0.8-0.5-0.40.4-0.9-0.7-0.6-0.0-0.1-0.3-0.2
Pavlov. Cond. magazine entry number0.50.64.00.90.80.8-2.0-0.60.60.60.50.5-0.40.80.70.3-0.20.30.6-0.3
Pavlov. Cond. intertrial magazine entries0.60.81.51.21.01.0-1.2-0.90.90.90.91.0-1.00.90.90.70.6-0.5-0.40.1
Pavlov. Cond. lever-magazine prob. diff.0.50.74.0-0.9-0.9-0.92.00.7-0.7-0.9-0.6-0.60.5-1.0-0.9-0.6-0.0-0.1-0.4-0.1
Pavlov. Cond. response bias0.30.32.1-0.5-0.6-0.61.50.4-0.4-0.6-0.4-0.30.3-0.8-0.6-0.40.1-0.2-0.4-0.1
Pavlov. Cond. lever latency7.610.319.84.44.24.2-3.9-3.43.43.23.53.5-3.43.43.12.41.8-1.5-1.0-0.6
Pavlov. Cond. magazine entry latency5.06.09.5-3.1-2.7-2.70.83.0-3.0-2.6-2.8-2.82.8-2.3-2.7-2.4-2.22.01.6-0.8
Pavlov. Cond. change in total contacts3.45.411.2-3.3-3.1-3.13.32.4-2.4-2.2-2.5-2.62.5-2.3-2.2-1.6-1.10.80.50.6
Pavlov. Cond. index score6.68.916.7-4.1-3.7-3.73.23.4-3.4-3.1-3.3-3.33.2-3.0-3.1-2.5-2.01.61.10.0
Pavlov. Cond. latency score6.68.716.0-4.0-3.7-3.72.83.4-3.4-3.1-3.3-3.33.2-2.9-3.1-2.5-2.11.71.3-0.1
Pavlov. Cond. lever contacts6.48.817.5-4.2-3.9-3.93.73.1-3.1-2.9-3.2-3.33.2-3.1-2.9-2.2-1.61.20.80.9
Pavlov. Cond. magazine entry number8.310.215.53.93.23.2-2.5-3.83.83.73.63.5-3.53.13.93.52.5-2.2-1.61.4
Pavlov. Cond. intertrial magazine entries2.84.35.92.01.51.50.1-2.32.32.42.22.2-2.31.72.32.42.4-2.4-2.31.5
Pavlov. Cond. lever-magazine prob. diff.6.18.115.4-3.9-3.5-3.53.13.2-3.2-3.0-3.2-3.23.1-2.8-3.0-2.4-1.81.51.00.0
Pavlov. Cond. response bias7.910.820.3-4.5-4.2-4.23.83.6-3.6-3.4-3.6-3.63.5-3.4-3.4-2.7-2.01.51.00.2
Time in closed arm before self-admin0.60.81.8-0.9-1.3-1.3-0.10.7-0.7-0.9-0.9-0.90.9-1.1-0.4-0.4-0.90.91.0-0.0
Time in closed arm after self-admin1.71.83.1-0.9-0.8-0.8-1.21.5-1.5-1.5-1.3-1.21.3-1.3-1.3-1.5-1.71.81.7-0.9
Time in open arm before self-admin1.31.44.61.51.41.4-2.1-1.21.21.11.11.2-1.21.11.00.80.8-0.7-0.7-0.3
Time in open arm after self-admin1.11.21.90.80.90.91.0-1.11.11.31.11.0-1.11.20.91.11.4-1.4-1.40.7
Bone: periosteal estimation0.20.54.5-0.40.30.32.10.3-0.30.20.00.1-0.10.3-0.7-0.30.7-0.9-1.3-0.3
Bone: periosteal perimeter0.30.43.1-0.4-0.1-0.11.80.0-0.00.10.0-0.0-0.00.1-0.30.00.8-0.9-1.01.2
Bone: post-yield work0.00.10.2-0.2-0.2-0.20.00.4-0.40.2-0.1-0.20.20.20.10.1-0.40.40.4-0.0
Progressive ratio test 1 active lever presses0.60.71.3-0.7-0.7-0.70.20.9-0.9-1.0-0.8-0.90.9-0.6-0.8-0.9-1.01.01.1-0.5
Progressive ratio test 1 breakpoint0.60.81.3-0.8-0.7-0.70.01.0-1.0-1.0-0.9-0.91.0-0.6-0.8-1.0-1.11.11.2-0.6
Progressive ratio test 1 inactive lever presses0.20.33.00.0-0.4-0.4-1.70.2-0.2-0.1-0.2-0.20.3-0.20.1-0.1-0.70.80.9-0.2
Progressive ratio test 2 active lever presses1.11.39.9-1.1-1.0-1.03.10.9-0.9-1.0-0.9-0.90.9-0.9-1.3-1.2-0.30.20.1-0.5
Progressive ratio test 2 breakpoint1.31.49.9-1.2-1.0-1.03.10.9-0.9-1.1-0.9-1.01.0-0.9-1.4-1.3-0.40.30.2-0.7
Progressive ratio test 2 inactive lever presses0.20.31.4-0.6-0.9-0.91.20.4-0.4-0.4-0.5-0.50.5-0.6-0.5-0.5-0.30.20.30.1
Incentive Sensitization - Responses0.81.211.0-1.0-1.3-1.33.30.4-0.4-0.6-0.6-0.60.6-1.1-0.9-0.70.1-0.3-0.30.3
Incentive Sensitization - Breakpoint0.91.211.1-0.9-1.3-1.33.30.3-0.3-0.5-0.6-0.60.6-1.1-0.9-0.70.2-0.3-0.30.3
Sum of active levers in priming session hrs 5-60.50.51.10.4-0.1-0.10.9-0.90.90.60.70.5-0.60.61.01.10.6-0.6-0.41.0
Progressive ratio1.52.33.4-1.5-1.0-1.0-0.41.8-1.8-1.6-1.7-1.61.6-1.1-1.8-1.8-1.61.51.3-1.5
Food seeking constrained by brief footshock0.40.51.4-0.1-0.3-0.30.2-0.50.50.60.30.3-0.40.50.71.01.0-1.0-1.11.2
Seeking ratio, punishment vs. effort2.73.96.51.50.90.90.9-2.42.42.02.11.9-2.01.42.32.52.5-2.5-2.21.9
Retroperitoneal fat weight7.029.839.55.56.36.30.2-5.85.86.16.05.8-5.85.84.95.25.8-5.7-5.33.5
Reaction time number correct0.20.43.2-0.1-0.7-0.7-1.80.1-0.10.1-0.2-0.20.2-0.20.70.6-0.60.70.90.5
Reaction time mean minus median0.10.21.2-0.3-0.4-0.41.10.1-0.10.10.10.1-0.1-0.30.10.40.4-0.5-0.61.0
Reaction time mean minus median AUC0.10.31.3-0.6-0.8-0.81.10.4-0.4-0.2-0.2-0.30.3-0.50.00.2-0.1-0.0-0.10.9
Reaction time num false alarms1.11.63.81.51.91.9-1.0-1.11.11.51.31.3-1.31.90.70.60.9-0.8-0.80.2
Reaction time num false alarms AUC0.20.41.10.81.11.1-0.6-0.40.40.60.50.6-0.61.00.10.00.3-0.2-0.3-0.2
Reaction time trials correct on left0.20.43.2-0.1-0.7-0.7-1.80.1-0.10.1-0.2-0.20.2-0.20.70.6-0.60.70.90.5
Reaction time trials on left0.20.43.1-0.1-0.7-0.7-1.80.1-0.10.1-0.2-0.30.2-0.20.70.6-0.60.70.90.5
Reaction time mean0.30.50.60.70.70.70.1-0.80.80.80.80.8-0.80.50.70.70.8-0.7-0.60.3
Reaction time mean AUC0.10.20.40.60.60.6-0.0-0.50.50.40.60.5-0.50.30.40.40.4-0.4-0.30.1
Median of all reaction times0.30.40.60.80.70.7-0.3-0.80.80.70.70.7-0.70.50.60.60.5-0.5-0.4-0.2
Reaction time omissions0.10.20.70.10.00.00.4-0.30.30.40.30.3-0.4-0.30.10.30.7-0.8-0.80.6
Reaction time false alarm rate0.40.51.90.81.41.40.1-0.30.30.50.60.6-0.61.0-0.3-0.40.4-0.4-0.6-0.7
Reaction time premature initiation rate2.43.36.81.21.11.11.6-1.91.91.81.81.7-1.81.31.41.82.5-2.6-2.51.7
Reaction time premature initiations1.11.93.50.90.50.50.7-1.51.51.51.31.3-1.30.81.51.81.8-1.9-1.81.7
Std. dev. reaction times0.30.61.40.40.30.31.1-0.60.60.60.70.7-0.70.20.50.71.1-1.1-1.21.1
Reaction time trials completed0.20.43.1-0.1-0.7-0.7-1.80.1-0.10.1-0.2-0.30.2-0.20.70.6-0.60.70.90.5
Reaction time trials AUC0.20.32.60.0-0.5-0.5-1.6-0.10.10.3-0.1-0.10.10.00.80.7-0.40.50.60.6
Run reversals in cocaine runway, females2.22.23.91.31.71.70.5-1.31.31.21.41.5-1.51.60.70.91.9-2.0-2.01.5
Run reversals in cocaine runway, males2.12.13.8-1.4-0.9-0.9-0.21.6-1.6-1.9-1.6-1.51.6-1.6-1.8-1.8-1.41.41.3-0.6
Latency to leave start box in cocaine runway1.71.93.21.81.51.5-1.1-1.61.61.41.51.5-1.51.61.51.31.0-0.9-0.8-0.4
Latency to leave start box in cocaine runway, F2.63.04.52.11.91.9-0.7-1.91.91.81.92.0-2.02.01.71.51.6-1.5-1.5-0.4
Latency to leave start box in cocaine runway, M0.10.10.4-0.0-0.2-0.2-0.4-0.00.0-0.3-0.2-0.20.2-0.30.1-0.1-0.40.50.6-0.4
Std. dev. time between licks in bursts1.82.54.21.20.70.70.5-1.61.61.71.61.6-1.61.31.61.92.0-2.1-2.01.9
Total sessions with >9 infusions1.41.72.7-1.5-1.6-1.60.91.3-1.3-1.2-1.4-1.41.3-1.5-1.3-1.2-1.00.90.7-1.3
Short access day 1 total inactive lever presses0.60.71.1-0.9-1.0-1.00.10.9-0.9-1.0-1.0-0.90.9-0.8-1.0-1.0-0.70.70.6-0.2
Short access day 10 total inactive lever presses0.51.34.01.40.60.6-2.0-1.41.41.01.11.1-1.10.81.51.30.6-0.4-0.11.2
Short access day 1 total infusions1.11.47.0-1.4-1.6-1.62.70.9-0.9-0.9-1.1-1.11.0-1.3-1.1-0.8-0.30.10.1-0.6
Short access day 10 total infusions1.21.63.0-1.4-1.1-1.11.71.4-1.4-1.2-1.3-1.21.2-1.2-1.5-1.4-0.80.70.5-1.4
Short access total infusions1.82.33.1-1.8-1.8-1.81.61.6-1.6-1.5-1.6-1.61.6-1.8-1.7-1.5-1.11.00.8-1.1
Short access day 1 locomotion3.34.15.8-2.4-2.4-2.40.72.2-2.2-2.1-2.2-2.32.2-2.4-2.0-1.9-1.81.71.6-0.6
Short access day 10 total locomotion0.61.02.8-1.2-1.5-1.51.71.0-1.0-0.9-0.9-0.90.9-1.3-0.9-0.7-0.50.40.30.1
Short access total locomotion0.81.02.4-1.1-1.5-1.50.41.0-1.0-0.8-1.0-1.01.0-1.3-0.7-0.7-0.90.90.9-0.2
One hour access (0.3 mA shock)0.70.84.7-1.0-1.1-1.12.20.7-0.7-0.8-0.7-0.70.7-1.0-0.9-0.7-0.20.10.1-0.1
Compulsive drug intake0.10.10.40.3-0.3-0.3-0.5-0.30.30.30.20.1-0.10.00.60.4-0.20.30.50.1
One hour access (shock baseline)1.42.13.1-1.7-1.6-1.61.51.6-1.6-1.5-1.5-1.51.5-1.8-1.7-1.5-1.10.90.7-0.7
Social response proportion2.22.54.41.81.21.2-0.8-1.81.81.81.81.7-1.71.42.12.01.4-1.2-1.01.2
Social responses2.83.64.72.01.81.8-0.6-2.22.22.12.02.0-2.01.81.91.92.0-2.0-1.71.7
Social time1.31.87.71.71.31.3-2.8-1.41.41.31.31.4-1.40.81.51.20.7-0.5-0.40.1
Soleus weight1.54.45.92.12.32.30.4-2.02.02.22.32.3-2.32.21.71.92.4-2.4-2.41.8
Bone: stiffness0.10.20.90.10.50.5-0.70.5-0.50.3-0.0-0.10.10.4-0.2-0.3-0.60.60.5-0.9
Tibialis anterior weight0.31.02.10.70.70.70.1-1.01.01.31.00.9-0.91.01.01.21.1-1.1-1.01.4
Time to tail flick, vehicle, before self-admin0.00.10.50.1-0.1-0.1-0.7-0.10.10.10.10.2-0.1-0.3-0.1-0.10.2-0.2-0.30.2
Time to tail flick, vehicle, after self-admin0.60.81.5-1.0-1.2-1.2-0.10.9-0.9-1.1-1.0-0.90.8-1.2-0.8-0.7-0.60.50.30.0
Time to tail flick, test, before self-admin0.40.41.8-0.31.11.11.40.6-0.6-0.2-0.2-0.20.20.8-0.8-0.6-0.0-0.1-0.4-0.4
Time to tail flick, test, after self-admin0.20.20.70.10.30.3-0.3-0.10.10.40.20.3-0.30.7-0.10.10.5-0.6-0.80.6
Delta time to tail flick, vehicle, before/after SA1.31.21.8-1.3-1.4-1.40.21.2-1.2-1.3-1.2-1.21.2-1.3-0.9-0.8-1.11.00.9-0.3
Delta time to tail flick, test, before/after SA0.60.63.00.7-0.3-0.3-1.7-0.90.90.80.60.6-0.60.31.10.90.4-0.3-0.10.7
Tibia length0.71.82.8-1.7-1.6-1.60.31.5-1.5-1.2-1.5-1.61.5-1.1-1.2-1.1-1.31.21.0-1.2
Ambulatory time before self-admin0.10.10.5-0.00.20.2-0.10.2-0.2-0.5-0.3-0.30.30.2-0.3-0.5-0.50.60.7-0.5
Ambulatory time after self-admin0.30.41.9-0.0-0.5-0.5-1.40.2-0.2-0.2-0.3-0.40.4-0.10.40.1-0.91.11.30.1
Bone: tissue strength0.40.42.40.1-0.1-0.1-1.50.3-0.30.1-0.1-0.30.3-0.00.50.1-1.11.21.4-0.2
Total heroin consumption0.20.21.70.20.40.41.3-0.40.40.20.20.2-0.20.50.30.30.2-0.2-0.10.1
Bone: trabecular number0.10.20.70.20.50.5-0.30.4-0.40.0-0.1-0.10.1-0.1-0.3-0.5-0.70.80.7-0.9
Bone: trabecular spacing0.30.41.4-0.9-1.2-1.2-0.40.4-0.4-0.6-0.7-0.70.6-0.7-0.3-0.2-0.30.30.3-0.2
Bone: trabecular thickness0.50.61.30.71.11.10.4-0.60.60.60.80.8-0.70.90.30.40.8-0.8-0.71.0
Bone: trabecular tissue density3.04.46.62.22.22.2-1.2-2.22.22.42.22.2-2.22.62.42.31.8-1.7-1.41.9
Water consumed over 24 hours0.30.30.60.80.70.70.3-0.70.70.50.60.6-0.60.70.70.60.3-0.3-0.10.6
Number of responses in last shaping day3.03.34.72.02.02.00.2-2.22.21.91.92.0-2.01.91.41.42.1-2.1-1.9-0.3