Hub : Genes

Cep295nl

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	alternative TSS	XM_006247814.4	0.12	0.07	5.5e-11	0.08	0.08	0.09	0.04	2.1e-09	3.0e-09	7.1e-10	4.1e-05
2	Adipose	alternative TSS	XM_006247817.4	0.13	0.08	5.1e-11	0.09	0.08	0.09	0.04	3.9e-10	1.5e-09	2.9e-10	1.0e-05
3	Adipose	alternative TSS	XM_006247817.4	0.23	0.11	0.0e+00	0.15	0.1	0.15	0.04	1.0e-16	3.5e-11	1.2e-16	1.3e-05
4	Adipose	alternative polyA	NM_001017481.1	0.06	0.04	3.8e-03	0.02	0	0.02	0.01	2.9e-03	1.4e-01	3.6e-03	2.2e-02
5	Adipose	alternative polyA	XM_006247817.4	0.06	0.04	3.5e-03	0.02	0	0.02	0.01	3.1e-03	1.4e-01	3.6e-03	2.6e-02
6	Adipose	alternative TSS	XM_006247814.4	0.32	0.15	1.1e-16	0.14	0.11	0.14	0.06	4.1e-15	3.8e-12	1.1e-15	5.0e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
Bone: apparent density	1.6	2.7	4.2	-2.0	2.0	2.1	-1.2	1.2	-1.1
Area under the delay curve	0.8	0.9	2.2	0.5	-0.5	-0.2	-1.5	1.5	-0.5
BMI with tail	3.4	11.0	17.7	2.2	-2.3	-2.9	4.2	-4.2	3.4
BMI without tail	0.3	0.6	0.9	-0.9	0.9	0.4	0.9	-0.9	0.6
Body weight	2.2	9.1	12.9	3.3	-3.3	-3.6	2.7	-2.7	2.3
Weight adjusted by age	0.2	0.2	0.3	-0.4	0.4	0.5	-0.5	0.5	-0.1
Bone surface	3.9	6.9	12.3	-1.7	1.7	2.4	-3.5	3.5	-2.3
Bone volume	3.0	5.0	7.1	-1.9	2.0	2.5	-2.7	2.7	-1.5
Breakpoint value in progressive ratio session	0.8	0.9	1.8	-1.1	1.1	1.3	-0.8	0.8	0.0
Number of licking bursts	0.0	0.1	0.1	0.3	-0.3	-0.3	-0.0	0.0	-0.1
Context. condit. distance diff. score	0.2	0.3	0.6	-0.4	0.4	0.4	-0.8	0.8	-0.4
Locomotion velocity, session 1	1.1	1.2	2.3	1.5	-1.5	-1.4	0.3	-0.3	0.4
Locomotion distance, session 1	0.5	0.7	1.4	-0.5	0.5	0.2	1.2	-1.2	0.9
Locomotion velocity, session 2	0.1	0.1	0.1	-0.3	0.3	0.2	0.4	-0.4	0.2
Locomotion distance, session 2	0.8	1.2	1.9	-1.1	1.1	0.4	1.4	-1.4	0.8
Locomotion velocity, session 3	0.2	0.2	0.4	0.6	-0.6	-0.6	-0.1	0.1	0.3
Locomotion distance, session 3	1.3	1.5	3.1	0.6	-0.6	-1.1	1.8	-1.8	0.8
Stereotopy head waving bouts, day 3	0.2	0.2	0.4	0.6	-0.6	-0.3	-0.3	0.3	0.1
Stereotopy head waving duration, day 3	0.4	0.4	1.2	0.2	-0.2	0.3	-1.1	1.1	-0.2
Locomotion velocity, session 7	0.8	0.9	1.3	-0.8	0.8	0.8	-1.1	1.1	-0.9
Locomotion distance, session 7	1.8	2.2	4.6	-2.1	2.1	1.8	-0.5	0.5	-0.7
Stereotopy head waving bouts, day 7	0.3	0.3	0.7	0.8	-0.8	-0.3	-0.6	0.6	-0.1
Stereotopy head waving duration, day 7	0.9	1.1	1.8	1.3	-1.3	-0.6	-1.2	1.2	-0.5
Locomotion velocity, session 8	1.0	1.2	2.8	-0.3	0.3	0.6	-1.7	1.7	-1.1
Locomotion distance, session 8	0.6	0.9	2.2	-1.5	1.4	1.0	0.1	-0.1	0.2
Degree of sensitization distance	6.2	6.2	8.9	-2.9	2.9	3.0	-2.2	2.2	-1.4
Degree of sensitization stereotypy	0.1	0.1	0.3	0.6	-0.5	-0.2	-0.3	0.3	-0.0
Conditioned locomotion	0.2	0.2	0.5	-0.6	0.6	0.7	-0.2	0.2	0.0
Cocaine response after cond. corrected	0.2	0.2	0.3	0.5	-0.5	-0.5	0.3	-0.3	0.4
Cocaine response after cond. not corrected	0.0	0.0	0.1	0.2	-0.2	-0.2	-0.3	0.3	0.1
Cocaine response before conditioning	1.2	1.4	2.2	-0.8	0.8	1.0	-1.5	1.5	-1.3
Saline control response	1.1	1.5	3.0	-0.2	0.2	0.4	-1.7	1.7	-1.7
Bone: connectivity density	2.9	4.6	5.4	-2.3	2.3	2.3	-1.9	1.9	-2.0
Bone: cortical apparent density	1.5	2.0	5.3	0.0	-0.1	-0.6	2.3	-2.3	0.9
Bone: cortical area	4.3	6.5	8.9	2.9	-2.9	-3.0	2.3	-2.3	1.7
Bone: cortical porosity	0.4	0.4	0.7	0.8	-0.8	-0.4	-0.7	0.7	-0.1
Bone: cortical porosity	0.6	0.6	1.0	0.8	-0.8	-0.3	-1.0	1.0	-0.2
Bone: cortical thickness	12.0	19.7	28.7	3.8	-3.9	-4.7	5.4	-5.4	3.0
Bone: cortical thickness	7.1	8.2	11.8	2.5	-2.5	-3.0	3.4	-3.4	2.2
Bone: cortical tissue density	1.3	1.7	4.7	-0.1	0.1	-0.5	2.2	-2.2	0.9
Condit. Reinf. active minus inactive responses	0.5	0.6	0.8	-0.8	0.8	0.9	-0.8	0.8	-0.4
Condit. Reinf. active-inactive response ratio	1.9	2.1	2.7	-1.5	1.5	1.7	-1.5	1.5	-1.1
Condit. Reinf. active responses	0.3	0.3	0.6	-0.7	0.7	0.8	-0.5	0.5	0.1
Condit. Reinf. inactive responses	0.2	0.2	0.8	-0.2	0.2	0.1	0.4	-0.4	0.9
Incentive salience index mean	0.3	0.4	0.6	-0.6	0.6	0.7	-0.7	0.7	-0.3
Condit. Reinf. lever presses	0.1	0.1	0.4	-0.2	0.2	0.3	-0.1	0.1	0.6
Condit. Reinf. active minus inactive responses	0.5	0.7	1.6	-0.1	0.1	0.5	-1.3	1.3	-0.7
Condit. Reinf. active-inactive response ratio	0.3	0.3	0.7	0.0	-0.0	0.2	-0.8	0.8	-0.6
Condit. Reinf. active responses	0.7	0.9	1.3	-0.9	0.9	1.1	-1.0	1.0	-0.6
Condit. Reinf. inactive responses	0.8	1.0	1.7	-1.2	1.2	1.3	-0.6	0.6	-0.4
Condit. Reinf. lever presses	1.7	2.3	3.9	-1.9	1.9	2.0	-1.1	1.1	-0.6
Condit. Reinf. lever reinforcers received	0.7	1.0	1.8	-1.1	1.1	1.3	-0.8	0.8	-0.3
Conditioned reinforcement - actives	0.3	0.3	0.4	-0.6	0.6	0.5	0.5	-0.5	-0.1
Conditioned reinforcement - inactives	0.2	0.2	0.4	0.4	-0.4	-0.4	0.7	-0.7	-0.2
Conditioned locomotion	0.6	0.7	1.3	-1.1	1.1	1.0	0.6	-0.6	0.1
Patch foraging indifference point 0 sec	0.5	0.8	1.7	-1.3	1.3	1.3	-0.1	0.1	0.3
Patch foraging indifference point AUC	1.5	1.8	2.3	-1.5	1.5	1.4	-1.2	1.2	-1.0
Delay disc. indifference point, 0s delay	0.5	0.6	1.1	1.1	-1.1	-1.1	-0.1	0.1	-0.1
Delay disc. indifference point, 16s delay	0.6	0.6	0.7	-0.9	0.9	0.9	-0.7	0.7	-0.4
Delay disc. indifference point, 2s delay	0.4	0.5	1.0	0.4	-0.4	-0.1	-1.0	1.0	0.8
Delay disc. indifference point, 24s delay	0.4	0.3	1.1	-0.3	0.3	0.3	-0.6	0.6	-1.0
Delay disc. indifference point, 4s delay	0.7	0.7	1.5	0.7	-0.7	-0.5	-1.2	1.2	0.1
Delay disc. indifference point, 8s delay	1.9	1.9	3.3	1.3	-1.3	-0.8	-1.8	1.8	-1.0
Indifference point function ln k	3.0	4.2	7.4	1.4	-1.4	-1.6	2.7	-2.7	1.9
Indifference point function log k	3.0	4.2	7.4	1.4	-1.4	-1.6	2.7	-2.7	1.9
Patch foraging total patch changes 0 sec	0.6	1.0	2.0	-1.4	1.4	1.4	-0.1	0.1	0.5
Patch foraging total patch changes 12 sec	1.5	1.9	4.1	-2.0	2.0	1.8	-0.3	0.3	-0.1
Patch foraging total patch changes 18 sec	4.6	5.9	8.6	-2.7	2.7	2.9	-2.3	2.3	-1.0
Patch foraging total patch changes 24 sec	1.8	2.2	4.5	-0.9	0.9	1.3	-2.1	2.1	-1.0
Patch foraging total patch changes 6 sec	0.7	1.0	2.3	-1.5	1.5	1.2	-0.2	0.2	-0.4
Patch foraging time to switch 0 sec	0.0	0.1	0.2	0.2	-0.2	-0.2	-0.1	0.1	-0.4
Patch foraging water rate 0 sec	0.3	0.5	0.7	-0.8	0.8	0.7	-0.7	0.7	-0.2
Patch foraging water rate 12 sec	1.3	2.0	5.0	0.3	-0.3	-0.8	2.2	-2.2	1.1
Patch foraging water rate 18 sec	0.2	0.2	0.5	-0.7	0.7	0.5	0.2	-0.2	0.0
Patch foraging water rate 24 sec	1.2	1.6	3.3	-1.8	1.8	1.6	-0.5	0.5	-0.1
Patch foraging water rate 6 sec	1.3	1.9	3.4	0.8	-0.9	-1.1	1.9	-1.9	1.2
Seeking ratio, delayed vs. immediate footshock	0.1	0.1	0.4	0.0	-0.0	-0.1	-0.2	0.2	-0.6
Distance traveled before self-admin	0.3	0.3	0.5	0.7	-0.7	-0.4	-0.5	0.5	-0.3
Distance traveled after self-admin	1.4	1.6	2.5	-1.6	1.5	1.5	-1.0	1.0	-0.3
Extensor digitorum longus weight	0.5	2.0	3.9	-1.1	1.1	0.6	2.0	-2.0	1.2
Bone: elastic displacement	1.9	2.2	5.3	0.4	-0.4	-0.9	2.3	-2.3	1.1
Bone: elastic work	3.0	3.9	5.8	1.7	-1.7	-2.1	2.4	-2.4	1.2
Bone: endosteal estimation	3.3	7.2	13.0	-1.9	2.0	2.9	-3.6	3.6	-1.0
Bone: endosteal perimeter	3.2	6.7	16.8	-0.5	0.6	1.8	-4.1	4.1	-1.7
Epididymis fat weight	0.8	1.8	2.5	1.0	-1.0	-1.2	1.6	-1.6	1.6
Delta time in closed arm before/after self-admin	1.4	1.4	3.3	-0.2	0.2	0.3	-1.8	1.8	-1.3
Delta time in open arm before/after self-admin	0.4	0.4	0.8	-0.9	0.9	0.7	0.1	-0.1	-0.3
Diff in mean of infusions in LGA sessions	0.6	0.7	1.3	-0.5	0.5	1.0	-1.1	1.1	0.1
Delay discount exponential model param	0.9	1.0	2.4	-0.7	0.7	0.3	1.6	-1.6	0.3
Extinction: sum of active levers before priming	0.3	0.3	0.6	0.4	-0.4	-0.5	0.8	-0.8	0.6
Active lever presses in extinction session 6	0.3	0.3	0.7	-0.8	0.8	0.8	0.1	-0.1	-0.1
Bone: final force	1.7	2.7	4.7	2.0	-2.1	-2.2	1.2	-1.2	0.6
Bone: final moment	1.6	2.6	4.3	2.0	-2.0	-2.1	1.2	-1.2	0.5
Food consumed during 24 hour testing period	2.0	2.5	3.9	-1.0	1.0	1.2	-2.0	2.0	-1.9
Glucose	0.6	0.9	1.7	0.6	-0.7	-1.0	1.3	-1.3	0.2
Heart weight	3.1	4.4	6.7	1.6	-1.6	-1.8	2.6	-2.6	2.1
Delay discount hyperbolic model param	0.9	0.9	2.2	-0.7	0.6	0.3	1.5	-1.5	0.2
Intermittent access intake day 1-15 change	0.3	0.3	1.6	0.2	-0.2	-0.1	-0.5	0.5	-1.2
Intermittent access intake escalation	0.8	0.8	2.2	-0.3	0.3	0.4	-1.0	1.0	-1.5
Intermittent access intake escalation 2	0.8	0.8	3.0	-0.5	0.5	0.5	-0.6	0.6	-1.7
Intermitt. access day 1 inactive lever presses	0.2	0.2	0.3	0.5	-0.5	-0.2	-0.4	0.4	-0.6
Intermitt. access day 15 inactive lever presses	0.3	0.3	0.6	-0.7	0.7	0.8	-0.3	0.3	-0.2
Intermitt. access escalation Index	1.4	1.2	2.5	-0.1	0.1	0.4	-1.6	1.6	-1.5
Intermittent access day 1 total infusions	0.7	0.9	2.8	0.5	-0.5	-0.5	0.9	-0.9	1.7
Intermittent access day 15 total infusions	0.1	0.1	0.3	-0.1	0.1	0.2	-0.6	0.6	-0.4
Intermittent access terminal intake (last 3 days)	0.1	0.1	0.2	-0.0	0.1	0.3	-0.4	0.4	-0.2
Intermittent access total infusions	0.0	0.0	0.3	0.1	-0.1	0.1	0.1	-0.1	0.5
Intermittent access day 1 locomotion	0.2	0.2	0.3	-0.5	0.5	0.4	0.4	-0.4	0.5
Intermittent access day 15 total locomotion	0.3	0.3	0.5	0.5	-0.5	-0.4	0.7	-0.7	0.6
Intermittent access total locomotion	0.1	0.2	0.3	-0.2	0.2	0.1	0.6	-0.6	0.5
Intermittent access standard deviation	2.3	2.4	5.0	2.2	-2.2	-1.9	0.5	-0.5	0.7
Left kidney weight	1.6	4.6	9.2	3.0	-3.0	-2.8	0.8	-0.8	0.7
Right kidney weight	1.3	3.7	5.7	2.4	-2.4	-2.4	1.4	-1.4	1.2
Cocaine induced anxiety	0.6	0.7	2.1	0.2	-0.2	-0.1	-1.0	1.0	-1.5
Post-drug Anxiety	1.0	1.1	1.8	-0.7	0.7	0.7	-1.3	1.3	-1.3
Baseline Anxiety	0.2	0.2	0.5	0.0	-0.0	-0.0	0.7	-0.7	0.6
Tail length	1.1	3.3	4.9	-1.4	1.4	1.4	-2.2	2.2	-2.0
Length with tail	0.5	1.9	3.7	1.9	-1.9	-1.7	-0.8	0.8	-0.6
Length without tail	3.9	8.5	14.9	3.9	-3.9	-3.7	1.7	-1.7	1.4
Times rat made contact with spout	0.8	0.9	1.1	-1.0	1.0	1.0	-0.8	0.8	-1.0
Lifetime Intake	0.1	0.2	0.4	0.3	-0.3	-0.3	0.4	-0.4	0.6
Liver weight, left	0.9	1.4	2.9	1.7	-1.7	-1.5	-0.1	0.1	0.3
Liver weight, right	1.3	2.2	3.3	1.8	-1.8	-1.8	1.0	-1.0	1.2
Locomotor activity	0.1	0.1	0.4	0.1	-0.1	0.0	0.1	-0.1	0.7
Locomotor testing distance	0.3	0.5	0.7	-0.6	0.6	0.8	-0.8	0.8	-0.1
Locomotor testing rearing	1.1	1.6	3.0	-1.6	1.6	1.7	-0.9	0.9	-0.5
Locomotion in novel chamber	3.4	4.2	5.5	-1.9	1.9	2.0	-2.4	2.4	-1.8
Locomotion in novel chamber post-restriction	1.2	1.5	2.5	-0.7	0.7	0.9	-1.6	1.6	-1.4
Fecal boli incidents, locomotor time 1	0.4	0.4	0.6	-0.8	0.8	0.8	0.2	-0.2	0.8
Change in fecal boli incidents, locomotor task	0.4	0.4	0.8	0.2	-0.2	-0.3	0.8	-0.8	0.9
Time >=10cm from walls, locomotor time 1	1.4	1.4	2.4	-0.7	0.7	0.8	-1.6	1.6	-1.5
Bouts of movement, locomotor time 1	1.0	1.0	1.9	0.6	-0.6	-0.7	1.4	-1.4	1.1
Total resting periods, locomotor time 1	0.7	0.8	1.6	0.5	-0.4	-0.6	1.3	-1.3	1.0
Rest time, locomotor task time 1	1.5	1.7	2.1	1.1	-1.1	-1.3	1.5	-1.5	1.4
Distance moved, locomotor task time 1	1.0	1.1	1.5	-0.8	0.8	0.9	-1.2	1.2	-1.2
Vertical activity count, locomotor time 1	1.1	1.1	1.8	-1.3	1.3	1.3	-0.8	0.8	-0.7
Time >=10cm from walls, locomotor time 2	0.2	0.2	0.4	-0.2	0.2	-0.1	0.6	-0.6	-0.7
Bouts of movement, locomotor time 2	0.0	0.0	0.1	0.1	-0.1	-0.0	-0.3	0.3	-0.2
Total resting periods, locomotor time 2	0.1	0.1	0.3	-0.1	0.1	0.1	-0.6	0.6	-0.4
Rest time, locomotor task time 2	0.2	0.3	0.8	0.2	-0.2	0.1	-0.5	0.5	0.9
Distance moved, locomotor task time 2	0.7	0.8	1.7	0.6	-0.6	-0.9	1.3	-1.3	0.3
Vertical activity count, locomotor time 2	0.6	0.6	1.4	0.4	-0.4	-0.5	1.2	-1.2	0.6
Light reinforcement 1	0.5	0.9	1.7	-1.3	1.3	1.0	0.6	-0.6	0.4
Light reinforcement 2	0.1	0.1	0.2	0.3	-0.3	-0.5	0.3	-0.3	0.0
Bone: marrow area	3.3	7.2	13.2	-1.9	1.9	2.9	-3.6	3.6	-1.0
Bone: maximum diameter	1.0	1.9	3.2	1.8	-1.8	-0.9	-1.4	1.4	-0.1
Bone: maximum force	1.1	2.0	3.0	1.7	-1.7	-1.7	1.1	-1.1	0.7
Bone: maximum moment	1.0	1.7	2.6	1.6	-1.6	-1.6	1.1	-1.1	0.6
Mean time between licks in bursts	0.1	0.1	0.3	0.2	-0.1	-0.2	0.5	-0.5	0.0
Mean num. licks in bursts	0.5	0.6	1.3	-1.1	1.1	1.0	-0.2	0.2	-0.3
Cd content in liver	1.6	1.7	4.4	0.2	-0.2	-0.6	2.1	-2.1	1.1
Co content in liver	0.5	0.6	1.0	-1.0	1.0	0.9	0.6	-0.6	0.1
Cu content in liver	0.2	0.2	0.5	0.3	-0.3	-0.3	0.7	-0.7	0.1
Fe content in liver	1.7	2.1	3.4	-1.1	1.1	1.5	-1.9	1.9	-0.9
K content in liver	0.5	0.5	0.9	-0.4	0.4	0.4	-0.9	0.9	-0.9
Mg content in liver	1.1	1.1	2.1	-1.5	1.4	1.2	-0.4	0.4	-0.8
Mn content in liver	0.5	0.5	0.8	0.8	-0.8	-0.7	-0.6	0.6	-0.9
Na content in liver	0.7	0.7	1.5	0.1	-0.1	0.1	-1.2	1.2	-1.2
Rb content in liver	0.6	0.7	1.6	-1.3	1.2	0.8	0.3	-0.3	-0.3
Se content in liver	1.9	2.3	3.2	-1.3	1.3	1.5	-1.8	1.8	-1.5
Sr content in liver	1.0	0.9	1.5	0.8	-0.8	-1.0	1.2	-1.2	0.4
Zn content in liver	0.8	0.9	1.7	1.3	-1.3	-1.1	0.5	-0.5	0.6
Bone: minimum diameter	0.4	0.8	2.0	0.5	-0.4	0.3	-1.4	1.4	-0.2
Time in familiar zone, hab. session 1	0.1	0.1	0.5	-0.1	0.1	0.1	0.4	-0.4	0.7
Time in novel zone, hab. session 1	0.3	0.3	1.2	0.2	-0.2	-0.2	-0.6	0.6	-1.1
Total zone transitions, hab. session 1	0.3	0.5	1.1	-1.1	1.0	0.7	0.2	-0.2	0.1
Total locomotion distance, hab. session 1	0.3	0.4	0.6	-0.7	0.7	0.4	0.6	-0.6	0.6
Locomotion velocity, hab. session 1	0.4	0.5	0.7	-0.7	0.7	0.3	0.8	-0.8	0.8
Time in familiar zone, hab. session 2	0.1	0.1	0.1	-0.2	0.2	-0.0	0.4	-0.4	-0.2
Time in novel zone, hab. session 2	0.1	0.1	0.2	0.2	-0.1	0.1	-0.5	0.5	-0.3
Total zone transitions, hab. session 2	1.4	1.8	4.0	-2.0	2.0	1.4	0.5	-0.5	0.4
Total locomotion distance, hab. session 2	1.1	1.5	2.3	-1.5	1.5	0.8	1.2	-1.2	0.7
Locomotion velocity, hab. session 2	1.0	1.4	2.1	-1.5	1.4	0.8	1.2	-1.2	0.7
Novel to familiar place preference ratio	1.3	1.4	3.0	-1.7	1.7	1.5	-0.0	0.0	-0.1
Novelty place preference	1.2	1.2	2.5	-1.6	1.6	1.5	-0.1	0.1	-0.1
Time in novel zone, NPP test	1.2	1.3	2.7	-1.7	1.7	1.5	-0.1	0.1	-0.0
Total zone transitions, NPP test	0.7	0.9	2.1	-1.4	1.4	0.9	0.6	-0.6	0.4
Total locomotion distance, NPP test	1.5	2.1	3.2	-1.5	1.4	0.7	1.8	-1.8	1.1
Locomotion velocity, NPP test	1.3	1.8	2.7	-1.4	1.3	0.7	1.6	-1.6	1.1
Intraocular pressure	1.6	2.2	4.4	-1.9	1.9	2.1	-0.8	0.8	-0.4
Delta distance traveled before/after self-admin	1.0	1.1	2.4	-1.6	1.5	1.3	-0.1	0.1	0.1
Delta ambulatory time before/after self-admin	1.9	2.0	4.1	-2.0	2.0	1.8	-0.6	0.6	-0.5
Parametrial fat weight	0.2	0.5	0.9	0.4	-0.5	-0.6	0.7	-0.7	0.9
Pavlov. Cond. lever latency	2.0	2.5	3.5	-1.9	1.9	1.8	-1.2	1.2	-1.5
Pavlov. Cond. magazine entry latency	0.6	0.8	1.3	1.1	-1.1	-0.6	-0.9	0.9	-0.0
Pavlov. Cond. change in total contacts	1.0	1.1	2.0	0.5	-0.5	-0.6	1.3	-1.3	1.4
Pavlov. Cond. index score	0.9	1.1	2.3	1.5	-1.5	-1.2	0.1	-0.1	0.8
Pavlov. Cond. latency score	1.4	1.8	3.7	1.9	-1.9	-1.6	0.3	-0.3	1.0
Pavlov. Cond. lever contacts	1.5	1.7	2.1	1.3	-1.3	-1.3	1.2	-1.2	1.5
Pavlov. Cond. magazine entry number	0.8	1.0	2.3	-1.5	1.5	1.1	0.4	-0.4	-0.3
Pavlov. Cond. intertrial magazine entries	1.0	1.3	2.6	-1.6	1.6	1.4	-0.3	0.3	-0.3
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.8	1.7	1.3	-1.3	-1.0	0.1	-0.1	0.8
Pavlov. Cond. response bias	0.8	0.9	1.9	1.4	-1.4	-1.1	0.2	-0.2	0.9
Pavlov. Cond. lever latency	2.3	3.2	5.8	2.2	-2.2	-2.4	1.3	-1.3	0.4
Pavlov. Cond. magazine entry latency	0.5	0.6	0.8	-0.9	0.9	0.9	0.5	-0.5	0.8
Pavlov. Cond. change in total contacts	1.3	1.8	3.8	-1.8	1.8	1.9	-0.3	0.3	0.1
Pavlov. Cond. index score	1.3	1.6	3.4	-1.6	1.7	1.8	-0.6	0.6	0.3
Pavlov. Cond. latency score	1.2	1.5	3.2	-1.5	1.5	1.8	-0.7	0.7	0.3
Pavlov. Cond. lever contacts	2.6	3.5	6.2	-2.2	2.2	2.5	-1.6	1.6	-0.5
Pavlov. Cond. magazine entry number	0.8	1.0	1.8	1.3	-1.3	-1.4	-0.3	0.3	-0.8
Pavlov. Cond. intertrial magazine entries	3.3	4.3	8.2	-1.3	1.3	1.7	-2.9	2.9	-1.7
Pavlov. Cond. lever-magazine prob. diff.	1.5	1.9	4.0	-1.8	1.8	2.0	-0.6	0.6	0.3
Pavlov. Cond. response bias	1.1	1.5	3.2	-1.6	1.6	1.8	-0.6	0.6	0.2
Time in closed arm before self-admin	1.7	2.0	3.0	1.1	-1.1	-1.3	1.7	-1.7	1.3
Time in closed arm after self-admin	1.2	1.2	2.5	1.6	-1.6	-1.3	-0.1	0.1	0.8
Time in open arm before self-admin	0.1	0.1	0.2	0.4	-0.4	-0.2	0.0	-0.0	-0.2
Time in open arm after self-admin	0.6	0.7	1.1	-1.1	1.1	1.0	-0.3	0.3	-0.7
Bone: periosteal estimation	0.3	0.5	1.1	0.6	-0.6	0.0	-1.1	1.1	0.3
Bone: periosteal perimeter	1.4	2.2	5.2	2.3	-2.3	-1.7	-0.3	0.3	0.4
Bone: post-yield work	0.7	1.0	1.9	-1.4	1.4	1.4	-0.3	0.3	-0.2
Progressive ratio test 1 active lever presses	0.6	0.6	0.8	-0.9	0.9	0.9	-0.7	0.7	-0.6
Progressive ratio test 1 breakpoint	0.2	0.2	0.4	-0.6	0.6	0.6	-0.4	0.4	-0.2
Progressive ratio test 1 inactive lever presses	0.0	0.0	0.1	0.2	-0.2	-0.1	-0.3	0.3	-0.0
Progressive ratio test 2 active lever presses	0.1	0.1	0.3	-0.5	0.5	0.5	0.2	-0.2	-0.1
Progressive ratio test 2 breakpoint	0.1	0.2	0.3	-0.5	0.5	0.5	0.3	-0.3	-0.2
Progressive ratio test 2 inactive lever presses	0.1	0.1	0.1	0.2	-0.2	-0.2	0.4	-0.4	0.2
Incentive Sensitization - Responses	0.6	0.7	1.3	0.7	-0.7	-0.6	1.1	-1.1	0.2
Incentive Sensitization - Breakpoint	0.6	0.6	1.1	0.8	-0.7	-0.6	1.1	-1.1	0.1
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.4	-0.4	0.4	0.7	-0.5	0.5	0.3
Progressive ratio	0.3	0.3	1.6	0.0	-0.0	0.1	0.5	-0.5	1.3
Food seeking constrained by brief footshock	0.8	1.0	2.2	1.1	-1.1	-0.8	0.7	-0.7	1.5
Seeking ratio, punishment vs. effort	0.1	0.1	0.2	0.3	-0.3	-0.1	-0.4	0.4	-0.4
Retroperitoneal fat weight	0.1	0.4	0.8	0.8	-0.8	-0.7	0.1	-0.1	0.9
Reaction time number correct	3.7	5.3	9.5	-3.1	3.1	2.9	-1.0	1.0	-1.4
Reaction time mean minus median	0.9	1.2	1.5	1.2	-1.2	-1.2	1.2	-1.2	0.6
Reaction time mean minus median AUC	0.4	0.5	1.1	1.0	-1.0	-0.9	0.3	-0.3	-0.3
Reaction time num false alarms	0.1	0.1	0.6	-0.1	0.1	0.2	-0.2	0.2	0.8
Reaction time num false alarms AUC	0.1	0.2	0.4	-0.5	0.5	0.5	-0.3	0.3	0.6
Reaction time trials correct on left	3.7	5.3	9.5	-3.1	3.1	2.9	-1.0	1.0	-1.4
Reaction time trials on left	3.7	5.3	9.4	-3.1	3.1	2.9	-1.0	1.0	-1.5
Reaction time mean	0.1	0.1	0.2	0.3	-0.3	-0.2	0.5	-0.5	0.3
Reaction time mean AUC	0.2	0.2	0.5	0.2	-0.2	-0.2	0.7	-0.7	0.5
Median of all reaction times	0.0	0.0	0.1	0.1	-0.1	-0.1	0.2	-0.2	0.3
Reaction time omissions	0.2	0.3	0.6	0.7	-0.7	-0.6	-0.1	0.1	-0.3
Reaction time false alarm rate	0.6	0.9	1.5	1.1	-1.2	-1.1	0.2	-0.2	1.2
Reaction time premature initiation rate	0.8	1.0	2.0	-0.8	0.8	0.2	1.4	-1.4	1.0
Reaction time premature initiations	1.9	2.7	6.0	-2.5	2.4	1.9	0.6	-0.6	0.0
Std. dev. reaction times	0.3	0.5	1.0	0.5	-0.5	-0.4	1.0	-1.0	0.5
Reaction time trials completed	3.7	5.3	9.4	-3.1	3.1	2.9	-1.0	1.0	-1.5
Reaction time trials AUC	3.9	5.6	10.3	-3.2	3.2	3.0	-1.0	1.0	-1.4
Run reversals in cocaine runway, females	0.5	0.5	2.4	0.4	-0.4	-0.2	0.3	-0.3	1.6
Run reversals in cocaine runway, males	2.3	2.3	3.1	1.2	-1.2	-1.4	1.8	-1.8	1.6
Latency to leave start box in cocaine runway	0.2	0.2	0.6	-0.1	0.1	-0.2	0.7	-0.7	0.2
Latency to leave start box in cocaine runway, F	0.1	0.1	0.3	-0.5	0.5	0.2	0.2	-0.2	-0.4
Latency to leave start box in cocaine runway, M	0.4	0.4	1.0	-0.2	0.2	-0.0	1.0	-1.0	0.7
Std. dev. time between licks in bursts	1.8	2.1	3.5	-1.9	1.9	1.8	-0.8	0.8	-1.1
Total sessions with >9 infusions	0.8	0.9	1.3	0.9	-0.9	-0.9	0.9	-0.9	1.2
Short access day 1 total inactive lever presses	0.0	0.0	0.0	0.2	-0.2	-0.2	0.2	-0.2	-0.1
Short access day 10 total inactive lever presses	0.2	0.2	0.4	0.6	-0.6	-0.4	-0.3	0.3	-0.6
Short access day 1 total infusions	0.6	0.7	1.0	1.0	-1.0	-0.9	0.6	-0.6	0.7
Short access day 10 total infusions	0.1	0.1	0.2	0.3	-0.3	0.0	-0.1	0.1	0.4
Short access total infusions	0.7	0.8	1.0	0.7	-0.7	-0.8	1.0	-1.0	1.0
Short access day 1 locomotion	1.3	1.4	2.2	1.3	-1.3	-1.5	0.8	-0.8	1.3
Short access day 10 total locomotion	0.5	0.6	0.9	0.7	-0.7	-0.7	1.0	-1.0	0.6
Short access total locomotion	4.0	4.1	4.9	1.9	-1.9	-2.2	2.1	-2.1	1.9
One hour access (0.3 mA shock)	0.3	0.3	0.8	-0.8	0.8	0.9	-0.1	0.1	-0.1
Compulsive drug intake	0.9	0.9	1.9	-0.3	0.3	0.2	1.4	-1.4	1.2
One hour access (shock baseline)	0.6	0.7	1.2	-0.4	0.4	0.6	-1.1	1.1	-0.9
Social response proportion	0.7	0.8	2.4	0.1	-0.1	-0.3	1.1	-1.1	1.5
Social responses	0.3	0.4	0.5	0.5	-0.5	-0.7	0.7	-0.7	0.7
Social time	0.8	1.1	2.7	-0.1	0.1	-0.2	1.6	-1.6	1.0
Soleus weight	0.8	2.2	5.6	0.2	-0.3	-0.7	2.4	-2.4	1.2
Bone: stiffness	1.7	2.6	4.2	2.0	-2.1	-2.0	1.0	-1.0	1.0
Tibialis anterior weight	0.3	0.9	2.3	0.1	-0.1	-0.4	1.5	-1.5	0.9
Time to tail flick, vehicle, before self-admin	0.5	0.5	1.4	-0.2	0.2	0.0	1.2	-1.2	0.2
Time to tail flick, vehicle, after self-admin	3.1	3.3	4.1	1.7	-1.7	-1.6	2.0	-2.0	1.7
Time to tail flick, test, before self-admin	0.7	0.6	0.8	-0.8	0.8	0.8	-0.9	0.9	-0.7
Time to tail flick, test, after self-admin	0.3	0.3	0.4	0.7	-0.6	-0.5	0.5	-0.5	0.2
Delta time to tail flick, vehicle, before/after SA	0.1	0.1	0.7	0.0	-0.0	0.2	0.2	-0.2	0.8
Delta time to tail flick, test, before/after SA	2.0	1.8	2.4	1.5	-1.5	-1.6	1.3	-1.3	0.7
Tibia length	6.0	17.0	36.8	6.1	-6.0	-5.3	-0.3	0.3	0.1
Ambulatory time before self-admin	0.7	0.8	1.7	1.3	-1.3	-1.0	-0.1	0.1	0.1
Ambulatory time after self-admin	0.8	0.9	1.3	-1.1	1.1	1.1	-0.8	0.8	-0.6
Bone: tissue strength	0.4	0.4	0.7	-0.8	0.8	0.6	0.6	-0.6	0.1
Total heroin consumption	0.3	0.3	0.6	0.6	-0.5	-0.1	-0.6	0.6	-0.7
Bone: trabecular number	1.3	2.0	2.2	-1.3	1.4	1.5	-1.5	1.5	-1.2
Bone: trabecular spacing	0.3	0.4	1.1	0.6	-0.6	-0.5	0.3	-0.3	1.1
Bone: trabecular thickness	0.8	0.9	1.7	-1.2	1.3	1.3	-0.5	0.5	-0.6
Bone: trabecular tissue density	0.7	1.0	1.7	1.1	-1.1	-1.0	0.7	-0.7	1.3
Water consumed over 24 hours	0.6	0.8	1.9	-0.7	0.7	0.7	-0.8	0.8	-1.4
Number of responses in last shaping day	2.3	2.4	3.9	2.0	-2.0	-1.9	0.8	-0.8	1.3