Hub : Genes

Celf5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb mRNA stability Celf5 0.25 0.15 1.2e-05 0.23 0.17 0.19 0.2 4.1e-06 8.3e-05 3.5e-05 1.5e-05
2 OFC mRNA stability Celf5 0.45 0.19 4.9e-08 0.27 0.21 0.21 0.23 4.4e-07 8.3e-06 9.7e-06 2.8e-06
3 Brain mRNA stability Celf5 0.16 0.1 1.9e-11 0.1 0.1 0.1 0.1 9.2e-10 3.3e-09 1.8e-09 1.9e-09
4 PL alternative TSS XM_008765105.3 0.04 0.03 4.5e-05 0.04 0.04 0.04 0.04 9.9e-06 5.5e-05 4.6e-05 4.5e-05
5 PL alternative TSS XM_008765105.3 0.04 0.03 1.7e-05 0.05 0.04 0.04 0.04 3.7e-06 1.8e-05 1.8e-05 1.7e-05
6 PL isoform ratio XM_008765105.3 0.03 0.02 7.5e-04 0.03 0.03 0.03 0.03 1.5e-04 3.5e-04 4.9e-04 4.0e-04
7 PL mRNA stability Celf5 0.05 0.04 4.0e-05 0.04 0.04 0.04 0.04 1.1e-05 7.6e-05 7.1e-05 4.8e-05
8 RMTg mRNA stability Celf5 0.12 0.09 4.9e-03 0.05 0.04 0.01 0.03 1.7e-02 3.2e-02 1.5e-01 5.1e-02
9 BLA mRNA stability Celf5 0.06 0.04 1.9e-03 0.06 0.05 0.05 0.06 3.9e-04 8.0e-04 1.3e-03 6.1e-04
10 NAcc mRNA stability Celf5 0.03 0.03 7.9e-04 0.03 0.02 0.03 0.03 2.3e-04 9.6e-04 6.3e-04 6.7e-04
11 NAcc isoform ratio XM_008765105.3 0.03 0.02 3.7e-04 0.02 0.02 0.03 0.02 4.0e-03 6.8e-04 5.6e-04 3.0e-03
12 NAcc alternative TSS XM_008765105.3 0.03 0.02 3.6e-04 0.02 0.03 0.03 0.02 2.9e-03 5.4e-04 2.9e-04 1.4e-03
13 NAcc alternative TSS XM_008765105.3 0.03 0.02 1.8e-04 0.02 0.03 0.03 0.03 1.7e-03 2.9e-04 1.5e-04 5.4e-04
14 IL mRNA stability Celf5 0.64 0.17 1.2e-09 0.18 0.18 0.18 0.19 3.9e-05 3.7e-05 3.7e-05 2.5e-05
15 IL intron excision ratio chr7_8244939_8246710 0.13 0.1 8.2e-03 0.05 0.01 0.01 0.02 2.8e-02 2.1e-01 2.1e-01 1.3e-01
16 PL intron excision ratio chr7_8226048_8232384 0.03 0.02 1.7e-03 0.03 0.02 0.03 0.02 5.1e-04 1.9e-03 8.9e-04 1.4e-03
17 PL intron excision ratio chr7_8226668_8232384 0.03 0.02 1.6e-03 0.03 0.02 0.03 0.02 4.3e-04 1.7e-03 8.2e-04 1.0e-03
18 OFC gene expression Celf5 0.19 0.12 1.2e-04 0.17 0.16 0.19 0.16 9.6e-05 1.0e-04 3.1e-05 1.0e-04
19 PL alternative TSS XM_039079023.1 0.04 0.03 4.2e-03 0 0.01 0.01 0.01 1.7e-01 3.4e-02 1.3e-02 5.7e-02
20 Brain gene expression Celf5 0.08 0.06 5.6e-04 0.04 0.03 0.03 0.03 2.8e-04 3.7e-04 4.3e-04 4.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.11.87.01.31.31.21.21.21.21.01.11.21.20.20.1-0.1-1.8-1.6-1.61.60.5-2.0-2.6
Area under the delay curve1.41.52.5-1.2-1.2-1.3-1.2-1.2-1.2-1.2-1.3-1.2-1.2-1.5-1.5-1.50.91.21.2-1.21.60.6-0.4
BMI with tail6.019.323.4-4.5-4.5-4.6-4.6-4.6-4.6-4.8-4.7-4.6-4.6-4.8-4.8-4.84.04.34.3-4.34.63.60.8
BMI without tail2.75.57.3-2.4-2.4-2.4-2.4-2.4-2.4-2.7-2.7-2.4-2.4-2.4-2.3-2.32.32.42.4-2.42.02.51.0
Body weight1.24.95.6-2.4-2.4-2.3-2.3-2.3-2.3-2.3-2.2-2.3-2.3-2.3-2.3-2.32.12.32.3-2.32.31.80.6
Weight adjusted by age0.60.61.4-0.8-0.8-0.7-1.0-1.0-1.0-1.0-1.0-0.7-0.7-0.6-0.6-0.50.80.80.8-0.80.41.20.7
Bone surface2.95.215.12.22.22.22.22.22.22.12.22.22.20.80.70.5-3.0-2.5-2.52.50.3-3.2-3.9
Bone volume3.15.215.12.32.32.22.22.22.22.12.22.22.20.80.70.5-3.1-2.6-2.62.60.2-3.3-3.9
Breakpoint value in progressive ratio session3.74.16.51.91.92.12.02.02.02.22.12.02.02.52.52.5-1.4-2.0-2.02.0-2.5-1.10.4
Number of licking bursts0.40.51.9-0.8-0.8-0.8-0.8-0.8-0.8-0.6-0.6-0.8-0.8-0.4-0.3-0.31.10.30.3-0.30.01.01.4
Context. condit. distance diff. score0.40.50.9-0.7-0.7-0.6-0.7-0.7-0.7-0.6-0.6-0.6-0.6-0.6-0.6-0.60.70.90.9-0.90.70.60.2
Locomotion velocity, session 11.21.32.31.31.31.31.31.31.31.21.31.31.31.00.90.9-1.5-0.5-0.50.5-0.6-1.4-1.4
Locomotion distance, session 10.70.93.41.01.00.91.01.01.00.90.90.90.90.40.30.3-1.4-0.2-0.20.20.0-1.3-1.8
Locomotion velocity, session 25.16.08.02.72.72.62.72.72.72.52.62.62.62.22.22.1-2.8-2.1-2.12.1-1.7-2.7-2.1
Locomotion distance, session 22.53.65.92.12.12.02.12.12.12.02.02.02.01.51.51.4-2.4-1.3-1.31.3-1.0-2.2-2.1
Locomotion velocity, session 35.26.07.82.52.52.62.52.52.52.52.62.62.62.82.82.8-2.1-2.4-2.42.4-2.8-1.8-0.2
Locomotion distance, session 30.00.00.10.00.00.00.00.00.0-0.10.00.00.00.10.10.10.00.00.0-0.0-0.20.10.2
Stereotopy head waving bouts, day 34.95.76.42.52.52.52.52.52.52.52.52.52.52.52.52.4-2.4-2.4-2.42.4-2.2-2.2-1.0
Stereotopy head waving duration, day 35.26.37.22.62.62.62.62.62.62.62.62.62.62.72.72.7-2.4-2.4-2.42.4-2.5-2.1-0.8
Locomotion velocity, session 71.01.11.51.11.11.01.11.11.11.11.01.01.01.00.90.9-1.1-1.2-1.21.2-0.9-1.0-0.6
Locomotion distance, session 70.20.30.8-0.5-0.5-0.5-0.5-0.5-0.5-0.6-0.5-0.5-0.5-0.3-0.2-0.20.70.40.4-0.40.00.70.9
Stereotopy head waving bouts, day 70.30.42.00.50.50.60.50.50.50.60.60.60.60.20.10.1-0.9-0.1-0.10.10.3-1.0-1.4
Stereotopy head waving duration, day 70.70.92.70.90.91.00.90.90.91.11.01.01.00.50.50.4-1.3-0.7-0.70.7-0.0-1.4-1.7
Locomotion velocity, session 81.41.74.11.41.41.41.41.41.41.41.41.41.40.90.80.7-1.7-0.9-0.90.9-0.2-1.8-2.0
Locomotion distance, session 80.10.20.50.60.60.50.60.60.60.60.50.50.50.30.30.3-0.70.00.0-0.0-0.2-0.5-0.7
Degree of sensitization distance0.30.30.5-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.7-0.7-0.70.50.50.5-0.50.70.40.0
Degree of sensitization stereotypy1.01.02.7-0.9-0.9-0.9-0.9-0.9-0.9-0.8-0.9-0.9-0.9-1.3-1.3-1.40.41.11.1-1.11.60.2-1.0
Conditioned locomotion2.93.44.5-2.0-2.0-2.0-2.0-2.0-2.0-2.0-2.0-2.0-2.0-1.6-1.5-1.42.11.71.7-1.71.12.01.7
Cocaine response after cond. corrected7.18.09.8-2.9-2.9-2.9-2.9-2.9-2.9-3.0-2.9-3.0-3.0-2.6-2.5-2.53.03.13.1-3.12.12.91.8
Cocaine response after cond. not corrected7.88.610.1-3.1-3.1-3.1-3.1-3.1-3.1-3.2-3.0-3.1-3.1-2.6-2.6-2.53.13.23.2-3.22.13.01.9
Cocaine response before conditioning0.70.81.30.90.91.01.01.01.00.81.00.90.90.80.80.8-0.9-1.1-1.11.1-0.7-0.9-0.6
Saline control response0.10.20.3-0.3-0.3-0.5-0.4-0.4-0.4-0.5-0.4-0.4-0.4-0.3-0.3-0.30.40.50.5-0.50.10.50.4
Bone: connectivity density0.40.63.90.60.60.50.50.50.50.30.50.50.5-0.3-0.4-0.5-1.1-0.8-0.80.80.8-1.2-2.0
Bone: cortical apparent density1.11.41.9-1.2-1.2-1.1-1.3-1.3-1.3-1.0-1.1-1.1-1.1-1.2-1.2-1.21.11.41.4-1.41.40.90.2
Bone: cortical area0.20.32.0-0.3-0.3-0.1-0.2-0.2-0.2-0.1-0.2-0.1-0.1-0.8-0.8-0.9-0.2-0.2-0.20.21.3-0.6-1.4
Bone: cortical porosity0.91.01.31.01.01.01.01.01.01.11.01.01.00.90.80.8-1.0-1.1-1.11.1-0.6-1.1-0.8
Bone: cortical porosity0.40.41.30.60.60.60.60.60.60.70.60.60.60.20.20.1-0.8-0.7-0.70.70.1-1.0-1.2
Bone: cortical thickness0.71.12.7-1.1-1.1-1.0-1.0-1.0-1.0-0.9-1.0-1.0-1.0-1.4-1.4-1.50.70.80.8-0.81.60.4-0.6
Bone: cortical thickness0.10.10.7-0.2-0.2-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.00.00.10.40.20.2-0.2-0.30.60.8
Bone: cortical tissue density0.81.11.5-1.1-1.1-0.9-1.1-1.1-1.1-0.9-0.9-1.0-1.0-1.0-1.0-1.01.01.21.2-1.21.20.80.2
Condit. Reinf. active minus inactive responses3.74.15.02.22.22.12.22.22.22.12.12.12.12.22.22.2-1.9-1.9-1.91.9-2.2-1.6-0.4
Condit. Reinf. active-inactive response ratio1.41.52.81.21.21.21.21.21.21.21.21.21.21.51.61.6-0.8-1.2-1.21.2-1.7-0.60.5
Condit. Reinf. active responses4.15.15.82.42.42.42.42.42.42.42.32.42.42.22.22.1-2.4-2.2-2.22.2-1.9-2.2-1.3
Condit. Reinf. inactive responses1.61.82.81.51.51.41.51.51.51.41.31.41.41.01.00.9-1.7-1.4-1.41.4-0.7-1.7-1.5
Incentive salience index mean2.63.23.71.91.91.91.91.91.91.91.91.91.91.71.71.7-1.9-1.7-1.71.7-1.4-1.8-1.1
Condit. Reinf. lever presses0.70.94.10.90.90.90.90.90.90.90.90.90.90.30.30.2-1.4-0.8-0.80.80.3-1.5-2.0
Condit. Reinf. active minus inactive responses1.51.83.81.31.31.21.21.21.21.31.31.21.21.71.71.8-0.8-1.5-1.51.5-1.9-0.60.8
Condit. Reinf. active-inactive response ratio0.30.32.6-0.4-0.4-0.4-0.4-0.4-0.4-0.3-0.4-0.4-0.40.20.20.30.80.20.2-0.2-0.70.91.6
Condit. Reinf. active responses2.13.04.01.81.81.71.71.71.71.71.71.71.71.81.81.8-1.5-2.0-2.02.0-1.9-1.2-0.0
Condit. Reinf. inactive responses1.82.22.71.71.71.51.61.61.61.51.61.51.51.31.31.2-1.6-1.6-1.61.6-1.1-1.4-0.9
Condit. Reinf. lever presses1.72.34.11.51.51.41.51.51.51.41.41.41.41.81.81.9-1.1-1.6-1.61.6-2.0-0.80.6
Condit. Reinf. lever reinforcers received1.52.03.21.51.51.31.41.41.41.41.41.31.31.61.61.6-1.1-1.7-1.71.7-1.8-0.90.3
Conditioned reinforcement - actives2.72.73.21.71.71.81.71.71.71.61.61.71.71.71.71.7-1.6-1.7-1.71.7-1.6-1.2-0.5
Conditioned reinforcement - inactives1.41.52.4-1.4-1.4-1.3-1.4-1.4-1.4-1.0-1.2-1.4-1.4-0.8-0.8-0.71.51.41.4-1.40.61.11.3
Conditioned locomotion7.28.710.53.03.03.03.03.03.03.03.13.03.03.23.23.2-2.6-3.0-3.03.0-3.2-2.2-0.3
Patch foraging indifference point 0 sec0.10.20.3-0.4-0.4-0.5-0.4-0.4-0.4-0.3-0.3-0.5-0.5-0.5-0.5-0.50.30.40.4-0.40.60.0-0.1
Patch foraging indifference point AUC0.81.01.41.01.01.11.01.01.00.80.91.11.11.01.11.1-0.9-1.0-1.01.0-1.2-0.4-0.0
Delay disc. indifference point, 0s delay3.94.39.7-2.0-2.0-2.0-2.0-2.0-2.0-1.9-2.0-1.9-1.9-2.6-2.7-2.81.12.02.0-2.03.10.5-1.6
Delay disc. indifference point, 16s delay0.10.10.2-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.4-0.4-0.40.10.30.3-0.30.40.1-0.2
Delay disc. indifference point, 2s delay3.84.27.3-2.0-2.0-2.1-2.0-2.0-2.0-2.0-2.1-2.0-2.0-2.4-2.5-2.51.42.02.0-2.02.71.0-0.8
Delay disc. indifference point, 24s delay0.40.40.8-0.6-0.6-0.7-0.6-0.6-0.6-0.9-0.8-0.8-0.8-0.7-0.7-0.70.40.60.6-0.60.70.6-0.1
Delay disc. indifference point, 4s delay0.40.51.5-0.5-0.5-0.6-0.5-0.5-0.5-0.6-0.6-0.6-0.6-0.9-1.0-1.00.10.50.5-0.51.2-0.1-1.1
Delay disc. indifference point, 8s delay1.31.31.5-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.1-1.1-1.1-1.1-1.11.21.21.2-1.20.91.00.7
Indifference point function ln k0.30.40.5-0.7-0.7-0.7-0.7-0.7-0.7-0.5-0.6-0.7-0.7-0.5-0.5-0.50.70.60.6-0.60.60.30.3
Indifference point function log k0.30.40.5-0.7-0.7-0.7-0.7-0.7-0.7-0.5-0.6-0.7-0.7-0.5-0.5-0.50.70.60.6-0.60.60.30.3
Patch foraging total patch changes 0 sec0.10.20.3-0.5-0.5-0.5-0.5-0.5-0.5-0.3-0.3-0.5-0.5-0.4-0.5-0.50.40.40.4-0.40.50.10.1
Patch foraging total patch changes 12 sec0.60.81.4-0.8-0.8-1.0-0.9-0.9-0.9-1.0-1.0-1.0-1.0-0.8-0.7-0.71.00.80.8-0.80.41.20.9
Patch foraging total patch changes 18 sec0.81.11.31.11.11.11.11.11.11.11.01.11.11.11.11.1-0.9-1.1-1.11.1-1.1-0.6-0.1
Patch foraging total patch changes 24 sec0.10.20.40.60.60.40.50.50.50.20.30.40.40.20.20.2-0.6-0.4-0.40.4-0.3-0.2-0.3
Patch foraging total patch changes 6 sec0.10.20.40.40.40.30.40.40.40.60.60.30.30.50.50.4-0.3-0.3-0.30.3-0.4-0.50.1
Patch foraging time to switch 0 sec0.81.23.0-0.9-0.9-1.1-1.0-1.0-1.0-0.8-1.1-1.1-1.1-1.5-1.5-1.60.50.90.9-0.91.70.1-1.0
Patch foraging water rate 0 sec0.20.42.1-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.3-0.5-0.50.00.10.20.80.50.5-0.5-0.51.11.4
Patch foraging water rate 12 sec1.82.84.2-1.8-1.8-1.7-1.8-1.8-1.8-1.9-1.6-1.7-1.7-1.3-1.2-1.22.01.81.8-1.80.92.11.6
Patch foraging water rate 18 sec0.81.16.4-0.8-0.8-0.8-0.8-0.8-0.8-0.9-0.7-0.8-0.80.10.20.31.40.80.8-0.8-0.81.82.5
Patch foraging water rate 24 sec2.43.39.8-1.8-1.8-1.9-1.9-1.9-1.9-1.7-1.6-1.9-1.9-0.7-0.7-0.52.51.81.8-1.8-0.12.43.1
Patch foraging water rate 6 sec0.20.43.20.00.0-0.1-0.0-0.0-0.0-0.1-0.0-0.1-0.10.60.60.70.50.00.0-0.0-1.20.91.8
Seeking ratio, delayed vs. immediate footshock5.76.57.42.72.72.62.72.72.72.62.72.62.62.62.62.5-2.5-2.7-2.72.7-2.3-2.3-0.9
Distance traveled before self-admin0.10.10.3-0.2-0.2-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.2-0.4-0.5-0.50.10.30.3-0.30.60.1-0.4
Distance traveled after self-admin1.11.21.61.31.31.11.21.21.21.21.21.11.11.11.11.0-1.2-1.1-1.11.1-1.1-0.9-0.4
Extensor digitorum longus weight4.919.323.0-4.8-4.8-4.7-4.6-4.6-4.6-4.6-4.7-4.6-4.6-4.4-4.4-4.34.64.14.1-4.13.94.12.1
Bone: elastic displacement0.30.30.40.50.50.60.60.60.60.70.60.70.70.70.70.7-0.5-0.4-0.40.4-0.5-0.5-0.2
Bone: elastic work0.10.10.4-0.3-0.3-0.1-0.2-0.2-0.2-0.0-0.1-0.1-0.1-0.4-0.4-0.40.00.30.3-0.30.6-0.1-0.6
Bone: endosteal estimation0.10.20.8-0.3-0.3-0.2-0.3-0.3-0.3-0.2-0.2-0.2-0.2-0.6-0.6-0.70.00.20.2-0.20.9-0.2-0.8
Bone: endosteal perimeter0.71.42.21.11.11.21.11.11.11.21.21.31.30.80.80.7-1.3-1.3-1.31.3-0.3-1.5-1.4
Epididymis fat weight0.10.10.60.10.10.30.30.30.30.20.10.30.30.50.60.60.1-0.3-0.30.3-0.80.20.7
Delta time in closed arm before/after self-admin2.32.24.9-1.5-1.5-1.5-1.5-1.5-1.5-1.8-1.6-1.4-1.4-1.0-0.9-0.81.91.41.4-1.40.22.12.2
Delta time in open arm before/after self-admin1.01.01.7-1.0-1.0-1.0-1.0-1.0-1.0-0.8-0.9-1.0-1.0-1.1-1.1-1.10.81.01.0-1.01.30.5-0.2
Diff in mean of infusions in LGA sessions1.31.41.91.21.21.31.21.21.21.21.21.21.21.41.41.4-1.0-1.2-1.21.2-1.3-0.8-0.0
Delay discount exponential model param1.31.42.21.21.21.21.21.21.21.21.21.21.21.41.41.4-0.8-1.2-1.21.2-1.5-0.60.4
Extinction: sum of active levers before priming0.50.51.70.50.50.60.50.50.50.60.40.50.51.01.11.1-0.1-0.6-0.60.6-1.30.21.1
Active lever presses in extinction session 63.13.03.71.81.81.91.81.81.81.91.61.81.81.91.91.9-1.6-1.8-1.81.8-1.7-1.3-0.5
Bone: final force0.50.82.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-1.3-1.4-1.40.20.40.4-0.41.7-0.1-1.2
Bone: final moment0.40.62.3-0.7-0.7-0.6-0.6-0.6-0.6-0.5-0.6-0.6-0.6-1.2-1.2-1.30.20.30.3-0.31.5-0.1-1.1
Food consumed during 24 hour testing period0.40.50.6-0.6-0.6-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.80.60.80.8-0.80.80.60.2
Glucose1.21.72.1-1.3-1.3-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.41.21.41.4-1.41.21.10.4
Heart weight0.20.20.90.40.40.40.40.40.40.20.40.40.40.60.70.7-0.2-0.3-0.30.3-0.90.20.7
Delay discount hyperbolic model param1.92.03.21.41.41.51.41.41.41.51.51.41.41.71.71.7-1.0-1.4-1.41.4-1.8-0.70.4
Intermittent access intake day 1-15 change5.15.07.82.22.22.32.22.22.22.52.32.22.22.72.82.8-1.7-2.2-2.22.2-2.8-1.60.3
Intermittent access intake escalation3.63.58.21.71.71.81.71.71.72.01.81.71.72.62.62.7-1.0-1.7-1.71.7-2.9-0.81.3
Intermittent access intake escalation 24.84.710.02.12.12.12.12.12.12.22.12.12.12.82.92.9-1.3-2.1-2.12.1-3.2-1.01.1
Intermitt. access day 1 inactive lever presses0.20.20.90.30.30.20.30.30.30.30.30.30.30.60.60.70.1-0.3-0.30.3-0.90.20.9
Intermitt. access day 15 inactive lever presses0.20.20.60.20.20.30.20.20.20.50.50.20.20.70.70.80.0-0.2-0.20.2-0.7-0.20.6
Intermitt. access escalation Index0.30.22.00.20.20.30.20.20.20.10.10.20.2-0.4-0.4-0.5-0.6-0.2-0.20.20.8-0.6-1.4
Intermittent access day 1 total infusions0.10.10.2-0.3-0.3-0.1-0.3-0.3-0.3-0.1-0.3-0.3-0.3-0.2-0.2-0.20.20.30.3-0.30.40.0-0.1
Intermittent access day 15 total infusions0.91.12.50.90.91.10.90.90.91.20.90.90.91.51.51.6-0.5-0.9-0.90.9-1.5-0.60.7
Intermittent access terminal intake (last 3 days)0.91.01.51.01.01.21.01.01.01.00.91.01.01.21.21.2-0.8-1.0-1.01.0-1.0-0.7-0.1
Intermittent access total infusions0.10.10.30.10.10.30.10.10.10.40.10.10.10.50.50.60.1-0.1-0.10.1-0.4-0.10.4
Intermittent access day 1 locomotion0.10.10.40.20.20.40.20.20.20.50.30.20.20.60.60.7-0.0-0.2-0.20.2-0.5-0.30.4
Intermittent access day 15 total locomotion2.42.64.71.51.51.71.51.51.51.81.81.51.52.12.12.2-1.1-1.5-1.51.5-2.0-1.10.5
Intermittent access total locomotion0.80.91.60.90.91.10.90.90.91.21.00.90.91.31.31.3-0.7-0.9-0.90.9-1.0-0.80.1
Intermittent access standard deviation2.22.34.01.51.51.61.51.51.51.51.41.51.51.91.92.0-1.1-1.5-1.51.5-2.0-0.80.4
Left kidney weight0.20.61.70.80.80.80.80.80.80.60.60.80.80.20.20.2-1.1-0.8-0.80.80.0-0.8-1.3
Right kidney weight1.64.45.32.22.22.22.32.32.32.12.12.22.22.12.12.0-2.0-2.3-2.32.3-1.9-1.7-0.8
Cocaine induced anxiety1.61.92.71.51.51.41.51.51.51.21.41.51.51.00.90.9-1.7-1.5-1.51.5-0.7-1.4-1.4
Post-drug Anxiety1.61.83.71.51.51.41.51.51.51.01.11.51.50.60.60.5-1.8-1.5-1.51.5-0.4-1.4-1.9
Baseline Anxiety0.10.10.3-0.2-0.2-0.2-0.2-0.2-0.2-0.1-0.2-0.2-0.20.00.00.10.30.20.2-0.2-0.20.50.6
Tail length2.37.010.62.72.72.72.62.62.62.82.72.72.73.13.23.2-2.0-2.5-2.52.5-3.3-1.70.5
Length with tail1.76.48.52.62.62.62.62.62.62.92.92.72.72.92.92.8-2.2-2.3-2.32.3-2.5-2.3-0.4
Length without tail0.20.51.70.60.60.60.70.70.70.91.00.70.70.50.40.4-0.8-0.6-0.60.60.0-1.3-1.0
Times rat made contact with spout0.40.40.8-0.6-0.6-0.8-0.7-0.7-0.7-0.8-0.8-0.8-0.8-0.5-0.5-0.50.70.40.4-0.40.20.90.9
Lifetime Intake0.00.00.10.10.10.30.10.10.10.30.10.10.10.30.30.3-0.1-0.1-0.10.1-0.1-0.10.0
Liver weight, left2.64.25.4-2.2-2.2-2.2-2.1-2.1-2.1-2.3-2.3-2.1-2.1-2.1-2.1-2.12.11.91.9-1.91.91.90.8
Liver weight, right1.42.33.0-1.6-1.6-1.5-1.6-1.6-1.6-1.6-1.6-1.5-1.5-1.7-1.7-1.71.41.51.5-1.51.71.10.1
Locomotor activity4.46.98.72.72.72.72.72.72.73.02.92.72.72.52.52.4-2.7-2.8-2.82.8-2.0-2.8-1.4
Locomotor testing distance2.33.85.01.91.92.12.02.02.02.22.22.02.02.01.91.9-1.9-1.9-1.91.9-1.6-1.9-0.9
Locomotor testing rearing0.00.00.1-0.0-0.00.1-0.0-0.0-0.0-0.00.00.00.00.20.20.20.10.10.1-0.1-0.10.20.3
Locomotion in novel chamber0.30.40.80.70.70.50.60.60.60.30.30.50.50.60.70.7-0.6-0.7-0.70.7-0.90.00.1
Locomotion in novel chamber post-restriction0.60.81.00.90.91.00.80.80.80.90.71.01.00.90.90.9-0.8-1.0-1.01.0-0.9-0.7-0.3
Fecal boli incidents, locomotor time 12.62.93.6-1.6-1.6-1.7-1.9-1.9-1.9-1.7-1.7-1.7-1.7-1.5-1.5-1.41.71.91.9-1.91.31.81.2
Change in fecal boli incidents, locomotor task1.21.12.20.90.91.11.11.11.11.01.01.21.20.70.60.6-1.2-1.1-1.11.1-0.3-1.4-1.5
Time >=10cm from walls, locomotor time 10.10.21.1-0.1-0.1-0.2-0.1-0.1-0.1-0.0-0.1-0.2-0.2-0.4-0.4-0.5-0.20.30.3-0.30.9-0.4-1.0
Bouts of movement, locomotor time 10.10.10.20.40.40.40.30.30.30.40.40.30.30.40.40.4-0.3-0.2-0.20.2-0.3-0.10.2
Total resting periods, locomotor time 10.20.20.30.50.50.60.40.40.40.50.60.40.40.50.50.5-0.5-0.4-0.40.4-0.4-0.3-0.1
Rest time, locomotor task time 10.20.30.50.60.60.60.50.50.50.70.60.50.50.50.50.5-0.6-0.4-0.40.4-0.2-0.5-0.5
Distance moved, locomotor task time 10.10.21.1-0.2-0.2-0.2-0.1-0.1-0.1-0.2-0.2-0.2-0.2-0.5-0.5-0.6-0.10.00.0-0.00.6-0.6-1.0
Vertical activity count, locomotor time 10.10.10.2-0.3-0.3-0.4-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.2-0.20.30.20.2-0.20.00.30.4
Time >=10cm from walls, locomotor time 21.41.51.9-1.4-1.4-1.3-1.3-1.3-1.3-1.1-1.3-1.4-1.4-1.1-1.1-1.11.41.21.2-1.20.91.20.7
Bouts of movement, locomotor time 20.90.91.51.01.01.01.01.01.01.01.01.01.00.70.70.6-1.2-0.9-0.90.9-0.3-1.2-1.2
Total resting periods, locomotor time 20.91.01.81.11.11.01.11.11.11.01.01.01.00.70.70.6-1.3-0.9-0.90.9-0.2-1.3-1.3
Rest time, locomotor task time 20.81.01.41.11.11.11.01.01.01.01.10.90.90.90.80.8-1.2-1.0-1.01.0-0.5-1.1-1.0
Distance moved, locomotor task time 21.21.42.0-1.4-1.4-1.3-1.2-1.2-1.2-1.1-1.2-1.3-1.3-1.0-1.0-0.91.41.21.2-1.20.71.21.0
Vertical activity count, locomotor time 21.61.82.8-1.5-1.5-1.4-1.4-1.4-1.4-1.2-1.3-1.3-1.3-1.0-1.0-0.91.71.41.4-1.40.61.61.5
Light reinforcement 15.39.611.33.43.43.13.23.23.23.33.33.13.13.33.33.2-2.9-3.1-3.13.1-3.2-2.6-0.5
Light reinforcement 21.62.23.01.51.51.51.41.41.41.71.71.51.51.61.61.6-1.3-1.5-1.51.5-1.4-1.4-0.2
Bone: marrow area0.10.20.8-0.4-0.4-0.2-0.3-0.3-0.3-0.2-0.2-0.2-0.2-0.6-0.6-0.70.10.20.2-0.20.9-0.1-0.7
Bone: maximum diameter1.42.63.91.51.51.71.61.61.61.81.71.71.71.21.11.0-1.8-1.9-1.91.9-0.6-2.0-1.8
Bone: maximum force0.61.03.1-1.0-1.0-0.9-0.9-0.9-0.9-0.8-0.9-0.9-0.9-1.5-1.5-1.50.50.60.6-0.61.80.2-0.9
Bone: maximum moment0.50.82.7-0.9-0.9-0.8-0.8-0.8-0.8-0.7-0.8-0.8-0.8-1.3-1.3-1.40.50.60.6-0.61.60.1-0.9
Mean time between licks in bursts2.83.96.02.02.02.12.02.02.02.12.12.12.12.42.42.4-1.5-1.8-1.81.8-2.5-1.10.5
Mean num. licks in bursts0.00.00.30.30.30.10.20.20.20.00.00.10.1-0.0-0.0-0.1-0.40.20.2-0.20.0-0.3-0.5
Cd content in liver0.10.10.2-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.4-0.5-0.50.20.10.1-0.10.40.1-0.1
Co content in liver0.40.51.00.50.50.50.60.60.60.70.60.50.50.80.80.8-0.2-0.9-0.90.9-1.0-0.30.5
Cu content in liver0.20.21.30.30.30.20.20.20.20.30.30.20.2-0.1-0.2-0.2-0.6-0.3-0.30.30.5-0.8-1.2
Fe content in liver0.10.10.5-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.20.00.00.10.40.10.1-0.1-0.20.50.7
K content in liver0.30.31.30.50.50.50.70.70.70.50.50.50.50.10.10.1-0.7-0.3-0.30.30.2-0.8-1.1
Mg content in liver0.50.52.10.60.60.70.80.80.80.60.60.60.60.20.10.0-0.9-0.5-0.50.50.2-1.0-1.4
Mn content in liver3.13.56.91.91.92.02.02.02.02.01.92.02.01.21.11.0-2.4-1.6-1.61.6-0.5-2.4-2.6
Na content in liver0.50.61.5-0.7-0.7-0.7-0.6-0.6-0.6-0.5-0.7-0.7-0.7-1.0-1.0-1.00.40.80.8-0.81.20.2-0.6
Rb content in liver0.20.22.0-0.1-0.10.10.10.10.10.0-0.00.00.0-0.5-0.6-0.6-0.40.10.1-0.11.0-0.5-1.4
Se content in liver0.20.30.40.60.60.50.60.60.60.50.50.50.50.50.50.5-0.6-0.4-0.40.4-0.5-0.5-0.3
Sr content in liver0.30.31.8-0.5-0.5-0.5-0.5-0.5-0.5-0.4-0.5-0.5-0.5-0.1-0.1-0.00.80.40.4-0.4-0.41.01.3
Zn content in liver0.91.03.70.60.60.70.80.80.80.60.60.60.61.41.41.50.0-0.7-0.70.7-1.90.31.7
Bone: minimum diameter0.10.21.30.30.30.40.30.30.30.40.40.40.4-0.0-0.1-0.1-0.6-0.5-0.50.50.4-0.8-1.1
Time in familiar zone, hab. session 11.51.42.51.21.21.21.21.21.21.11.21.21.21.41.41.5-0.9-1.1-1.11.1-1.6-0.70.3
Time in novel zone, hab. session 10.40.41.5-0.5-0.5-0.5-0.5-0.5-0.5-0.4-0.5-0.5-0.5-0.9-0.9-1.00.00.10.1-0.11.2-0.3-1.2
Total zone transitions, hab. session 11.62.23.41.61.61.61.61.61.61.61.61.61.61.21.11.1-1.8-1.2-1.21.2-0.8-1.7-1.6
Total locomotion distance, hab. session 12.73.86.42.12.12.02.12.12.12.02.02.02.01.41.31.2-2.5-1.7-1.71.7-0.8-2.5-2.5
Locomotion velocity, hab. session 12.73.85.82.12.12.12.12.12.12.02.12.12.11.61.51.4-2.4-1.8-1.81.8-1.1-2.3-2.1
Time in familiar zone, hab. session 24.34.48.02.12.12.12.12.12.12.02.12.12.12.62.62.7-1.5-2.1-2.12.1-2.8-1.10.8
Time in novel zone, hab. session 22.82.85.9-1.6-1.6-1.6-1.6-1.6-1.6-1.5-1.6-1.6-1.6-2.1-2.1-2.21.01.61.6-1.62.40.6-1.0
Total zone transitions, hab. session 20.30.43.30.40.40.20.40.40.40.30.20.20.2-0.3-0.4-0.5-0.90.50.5-0.50.7-0.8-1.8
Total locomotion distance, hab. session 21.31.73.01.61.61.41.61.61.61.41.41.41.41.11.01.0-1.7-0.7-0.70.7-0.9-1.5-1.4
Locomotion velocity, hab. session 21.52.03.71.71.71.51.71.71.71.51.51.51.51.11.00.9-1.9-0.8-0.80.8-0.7-1.7-1.8
Novel to familiar place preference ratio2.12.15.2-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.8-1.9-2.00.71.51.5-1.52.30.3-1.3
Novelty place preference1.11.13.1-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-1.4-1.4-1.50.31.11.1-1.11.80.1-1.3
Time in novel zone, NPP test1.31.43.5-1.0-1.0-1.0-1.0-1.0-1.0-1.1-1.0-1.0-1.0-1.5-1.5-1.60.51.21.2-1.21.90.2-1.2
Total zone transitions, NPP test0.10.10.90.30.30.20.30.30.30.20.20.20.2-0.1-0.1-0.2-0.60.40.4-0.40.2-0.4-0.9
Total locomotion distance, NPP test0.20.31.90.50.50.30.50.50.50.30.30.30.3-0.1-0.1-0.2-0.80.10.1-0.10.3-0.8-1.4
Locomotion velocity, NPP test0.30.41.80.70.70.60.70.70.70.60.60.60.60.20.20.1-1.0-0.1-0.10.10.0-0.9-1.3
Intraocular pressure0.20.32.1-0.3-0.3-0.4-0.4-0.4-0.4-0.7-0.5-0.4-0.4-0.00.00.10.70.40.4-0.4-0.61.21.4
Delta distance traveled before/after self-admin1.51.62.01.41.41.31.31.31.31.31.41.31.31.41.41.4-1.2-1.3-1.31.3-1.4-1.1-0.2
Delta ambulatory time before/after self-admin2.02.22.71.61.61.61.61.61.61.51.61.51.51.41.41.4-1.6-1.5-1.51.5-1.4-1.3-0.7
Parametrial fat weight0.30.61.10.70.70.70.60.60.60.80.90.70.71.01.11.1-0.4-0.9-0.90.9-1.0-0.60.4
Pavlov. Cond. lever latency0.20.31.8-0.5-0.5-0.5-0.5-0.5-0.5-0.4-0.5-0.5-0.5-0.0-0.00.10.80.40.4-0.4-0.30.91.3
Pavlov. Cond. magazine entry latency2.02.53.71.71.71.71.71.71.71.71.71.71.71.91.91.9-1.3-1.4-1.41.4-1.9-1.10.1
Pavlov. Cond. change in total contacts0.10.10.10.30.30.30.30.30.30.30.30.30.30.30.30.3-0.3-0.0-0.00.0-0.3-0.2-0.2
Pavlov. Cond. index score0.60.81.11.01.00.91.01.01.00.90.90.90.90.70.70.7-1.1-0.7-0.70.7-0.5-1.0-0.9
Pavlov. Cond. latency score0.81.01.71.11.11.11.11.11.11.11.11.11.10.70.70.6-1.3-0.8-0.80.8-0.4-1.3-1.3
Pavlov. Cond. lever contacts0.60.72.60.80.80.80.80.80.80.70.80.80.80.30.30.2-1.2-0.8-0.80.80.1-1.3-1.6
Pavlov. Cond. magazine entry number0.50.60.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.9-0.9-0.90.70.60.6-0.60.80.60.1
Pavlov. Cond. intertrial magazine entries0.10.10.9-0.1-0.1-0.2-0.1-0.1-0.1-0.1-0.2-0.1-0.10.20.20.20.4-0.0-0.00.0-0.50.51.0
Pavlov. Cond. lever-magazine prob. diff.1.01.21.61.21.21.21.21.21.21.21.21.21.21.01.00.9-1.2-0.9-0.90.9-0.8-1.2-0.9
Pavlov. Cond. response bias0.91.11.31.11.11.11.11.11.11.11.11.11.11.21.11.1-1.0-1.0-1.01.0-1.1-0.9-0.3
Pavlov. Cond. lever latency1.01.41.7-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.21.11.31.3-1.31.11.00.3
Pavlov. Cond. magazine entry latency0.80.91.30.90.91.00.90.90.91.01.01.01.00.90.90.9-0.9-1.2-1.21.2-0.6-1.0-0.6
Pavlov. Cond. change in total contacts0.91.21.61.11.11.11.11.11.11.11.01.11.11.21.21.2-0.9-1.3-1.31.3-1.2-0.80.0
Pavlov. Cond. index score1.11.41.91.21.21.21.21.21.21.21.21.21.21.21.21.2-1.0-1.4-1.41.4-1.1-1.0-0.2
Pavlov. Cond. latency score1.11.42.11.21.21.21.21.21.21.21.21.21.21.21.21.2-1.1-1.4-1.41.4-1.0-1.1-0.5
Pavlov. Cond. lever contacts0.70.91.31.01.01.01.01.01.00.90.91.01.01.11.11.1-0.8-1.0-1.01.0-1.2-0.60.1
Pavlov. Cond. magazine entry number1.21.51.9-1.2-1.2-1.3-1.2-1.2-1.2-1.3-1.3-1.3-1.3-1.2-1.2-1.21.21.41.4-1.40.91.20.6
Pavlov. Cond. intertrial magazine entries0.91.22.0-1.0-1.0-1.2-1.1-1.1-1.1-0.9-1.1-1.2-1.2-0.9-0.9-0.91.11.41.4-1.40.61.30.9
Pavlov. Cond. lever-magazine prob. diff.1.21.52.01.21.21.31.21.21.21.31.31.31.31.31.21.2-1.1-1.4-1.41.4-1.1-1.1-0.4
Pavlov. Cond. response bias1.62.23.11.51.51.51.51.51.51.51.51.51.51.71.71.8-1.2-1.6-1.61.6-1.7-1.00.1
Time in closed arm before self-admin0.30.41.4-0.4-0.4-0.5-0.4-0.4-0.4-0.3-0.2-0.5-0.5-0.8-0.9-0.90.00.50.5-0.51.2-0.4-1.1
Time in closed arm after self-admin0.00.00.10.20.2-0.00.20.20.2-0.20.00.10.1-0.0-0.0-0.0-0.2-0.1-0.10.1-0.30.10.1
Time in open arm before self-admin0.80.91.81.01.00.90.90.90.90.90.90.90.91.11.11.2-0.7-1.0-1.01.0-1.3-0.40.3
Time in open arm after self-admin0.91.01.4-1.2-1.2-1.0-1.1-1.1-1.1-0.8-0.9-1.1-1.1-0.8-0.8-0.81.21.01.0-1.01.00.70.5
Bone: periosteal estimation0.20.32.5-0.2-0.2-0.0-0.1-0.1-0.10.1-0.0-0.0-0.0-0.7-0.8-0.8-0.4-0.2-0.20.21.3-0.7-1.6
Bone: periosteal perimeter0.61.02.90.80.81.00.90.90.91.01.01.01.00.40.30.2-1.2-1.2-1.21.20.2-1.4-1.7
Bone: post-yield work0.60.81.1-0.9-0.9-0.9-1.0-1.0-1.0-0.8-0.9-0.9-0.9-1.0-1.0-1.00.80.70.7-0.71.00.70.1
Progressive ratio test 1 active lever presses0.30.30.5-0.7-0.7-0.5-0.7-0.7-0.7-0.5-0.7-0.7-0.7-0.3-0.3-0.30.70.70.7-0.70.30.60.5
Progressive ratio test 1 breakpoint0.30.40.5-0.7-0.7-0.5-0.7-0.7-0.7-0.6-0.7-0.7-0.7-0.4-0.4-0.40.70.70.7-0.70.50.60.4
Progressive ratio test 1 inactive lever presses0.00.00.00.00.00.10.00.00.00.10.10.00.00.10.10.1-0.0-0.0-0.00.0-0.0-0.10.0
Progressive ratio test 2 active lever presses0.10.10.30.20.20.30.20.20.20.20.10.20.20.50.50.6-0.0-0.2-0.20.2-0.60.10.5
Progressive ratio test 2 breakpoint0.30.30.50.60.60.70.60.60.60.50.30.60.60.60.70.7-0.5-0.6-0.60.6-0.6-0.3-0.1
Progressive ratio test 2 inactive lever presses0.10.10.10.20.20.40.20.20.20.30.30.20.20.30.30.3-0.3-0.2-0.20.2-0.1-0.3-0.2
Incentive Sensitization - Responses0.20.20.50.40.40.50.40.40.40.20.20.40.40.60.60.6-0.2-0.4-0.40.4-0.70.10.4
Incentive Sensitization - Breakpoint0.30.30.60.60.60.60.60.60.60.30.30.60.60.60.70.7-0.4-0.6-0.60.6-0.8-0.00.1
Sum of active levers in priming session hrs 5-60.00.00.1-0.2-0.2-0.1-0.2-0.2-0.20.1-0.3-0.2-0.2-0.0-0.0-0.00.20.10.1-0.10.10.20.2
Progressive ratio0.30.30.8-0.5-0.5-0.5-0.5-0.5-0.5-0.9-0.7-0.5-0.5-0.5-0.5-0.40.60.50.5-0.50.20.90.6
Food seeking constrained by brief footshock0.10.10.20.40.40.30.50.50.50.20.30.30.30.20.20.2-0.3-0.5-0.50.5-0.5-0.1-0.0
Seeking ratio, punishment vs. effort0.10.20.50.30.30.30.30.30.30.70.50.30.30.30.30.2-0.4-0.4-0.40.4-0.2-0.6-0.3
Retroperitoneal fat weight0.72.33.3-1.7-1.7-1.6-1.7-1.7-1.7-1.2-1.3-1.6-1.6-1.2-1.2-1.21.71.81.8-1.81.21.21.0
Reaction time number correct1.21.72.8-1.4-1.4-1.4-1.3-1.3-1.3-1.5-1.3-1.4-1.4-1.0-1.0-0.91.51.41.4-1.40.61.71.3
Reaction time mean minus median0.81.11.51.01.01.21.11.11.10.91.01.21.21.11.11.1-1.0-1.0-1.01.0-0.8-0.8-0.5
Reaction time mean minus median AUC0.50.63.00.70.70.90.70.70.70.60.70.90.90.30.20.2-1.1-0.5-0.50.50.4-1.1-1.7
Reaction time num false alarms0.10.10.4-0.2-0.2-0.3-0.3-0.3-0.3-0.4-0.5-0.3-0.3-0.3-0.3-0.20.30.40.4-0.40.00.60.4
Reaction time num false alarms AUC0.30.41.0-0.5-0.5-0.6-0.6-0.6-0.6-0.7-0.8-0.6-0.6-0.4-0.4-0.30.60.70.7-0.70.11.00.8
Reaction time trials correct on left1.21.72.8-1.4-1.4-1.4-1.3-1.3-1.3-1.5-1.3-1.4-1.4-1.0-1.0-0.91.51.41.4-1.40.61.71.3
Reaction time trials on left1.11.62.6-1.3-1.3-1.3-1.3-1.3-1.3-1.4-1.3-1.3-1.3-1.0-1.0-0.91.51.31.3-1.30.61.61.3
Reaction time mean0.20.31.70.40.40.60.40.40.40.30.50.60.60.10.0-0.0-0.7-0.4-0.40.40.4-0.8-1.3
Reaction time mean AUC0.20.21.50.20.20.50.30.30.30.30.40.40.4-0.0-0.1-0.1-0.6-0.3-0.30.30.5-0.7-1.2
Median of all reaction times0.10.21.4-0.2-0.20.0-0.1-0.1-0.1-0.1-0.1-0.0-0.0-0.5-0.5-0.6-0.20.10.1-0.10.9-0.4-1.2
Reaction time omissions0.30.40.60.70.70.70.60.60.60.70.70.70.70.60.60.6-0.7-0.5-0.50.5-0.4-0.6-0.5
Reaction time false alarm rate0.00.00.00.20.20.10.10.10.10.0-0.10.10.1-0.1-0.1-0.1-0.20.10.1-0.10.10.0-0.2
Reaction time premature initiation rate0.40.51.80.50.50.50.60.60.60.90.80.60.61.11.11.1-0.1-0.4-0.40.4-1.3-0.11.0
Reaction time premature initiations0.30.43.2-0.1-0.1-0.1-0.0-0.0-0.00.20.1-0.1-0.10.60.70.70.70.30.3-0.3-1.10.81.8
Std. dev. reaction times0.40.61.00.80.81.00.80.80.80.60.81.01.00.60.60.6-0.9-0.6-0.60.6-0.2-0.7-1.0
Reaction time trials completed1.11.62.6-1.3-1.3-1.3-1.3-1.3-1.3-1.4-1.3-1.3-1.3-1.0-1.0-0.91.51.31.3-1.30.61.61.3
Reaction time trials AUC1.31.83.1-1.4-1.4-1.4-1.4-1.4-1.4-1.5-1.3-1.4-1.4-1.0-1.0-0.91.61.41.4-1.40.51.81.5
Run reversals in cocaine runway, females1.31.32.01.31.31.11.41.41.40.81.21.11.10.80.70.7-1.3-1.3-1.31.3-0.9-0.9-0.9
Run reversals in cocaine runway, males1.81.72.31.41.41.41.51.51.51.21.21.41.41.01.01.0-1.4-1.5-1.51.5-1.1-1.2-0.9
Latency to leave start box in cocaine runway2.02.23.31.61.61.61.41.41.41.71.61.51.51.21.21.1-1.8-1.5-1.51.5-0.5-1.8-1.6
Latency to leave start box in cocaine runway, F0.91.04.90.90.91.00.80.80.81.00.90.80.80.20.20.1-1.4-0.9-0.90.90.5-1.6-2.2
Latency to leave start box in cocaine runway, M1.71.63.21.21.21.21.21.21.21.21.21.21.21.71.71.8-0.7-1.1-1.11.1-1.8-0.31.0
Std. dev. time between licks in bursts1.41.72.31.31.31.31.31.31.31.41.41.31.31.01.01.0-1.5-1.4-1.41.4-0.7-1.5-1.2
Total sessions with >9 infusions0.20.31.20.50.50.60.50.50.50.30.30.50.50.10.10.1-0.8-0.5-0.50.50.2-0.5-1.1
Short access day 1 total inactive lever presses0.00.00.00.10.10.20.10.10.10.1-0.00.10.10.20.20.2-0.1-0.1-0.10.1-0.2-0.00.0
Short access day 10 total inactive lever presses0.10.10.7-0.2-0.2-0.2-0.2-0.2-0.2-0.00.0-0.2-0.20.20.20.30.40.20.2-0.2-0.40.30.8
Short access day 1 total infusions0.50.51.30.70.70.90.70.70.70.60.50.70.70.40.40.3-0.9-0.7-0.70.70.0-0.8-1.1
Short access day 10 total infusions0.00.00.1-0.0-0.00.2-0.0-0.0-0.0-0.0-0.2-0.0-0.00.10.10.1-0.00.00.0-0.00.10.1-0.1
Short access total infusions0.10.10.60.30.30.50.30.30.30.10.10.30.30.10.10.0-0.5-0.3-0.30.30.2-0.2-0.8
Short access day 1 locomotion1.01.01.90.90.91.10.90.90.91.41.40.90.91.11.11.1-0.9-0.9-0.90.9-0.7-1.3-0.5
Short access day 10 total locomotion2.93.25.51.71.71.81.71.71.72.02.01.71.72.32.32.4-1.2-1.7-1.71.7-2.3-1.20.5
Short access total locomotion0.91.01.51.01.01.21.01.01.01.11.21.01.01.21.21.1-0.9-1.0-1.01.0-0.8-0.9-0.3
One hour access (0.3 mA shock)0.30.30.4-0.7-0.7-0.5-0.7-0.7-0.7-0.4-0.6-0.7-0.7-0.4-0.4-0.40.60.70.7-0.70.50.30.3
Compulsive drug intake0.60.61.2-0.7-0.7-0.9-0.7-0.7-0.7-0.7-0.8-0.7-0.7-1.1-1.1-1.10.50.70.7-0.70.90.3-0.2
One hour access (shock baseline)0.10.10.6-0.3-0.3-0.1-0.3-0.3-0.30.0-0.2-0.3-0.30.20.20.30.50.30.3-0.3-0.20.30.7
Social response proportion0.80.91.21.01.01.11.11.11.10.90.91.11.10.90.90.9-1.0-0.9-0.90.9-0.7-0.9-0.6
Social responses8.711.113.43.53.53.63.73.73.73.33.43.63.63.33.33.3-3.4-3.3-3.33.3-3.0-2.9-1.5
Social time1.01.32.0-1.2-1.2-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-0.9-0.9-0.91.21.41.4-1.40.90.90.5
Soleus weight7.722.728.2-5.1-5.1-4.9-4.9-4.9-4.9-5.1-4.9-4.9-4.9-5.3-5.3-5.34.44.54.5-4.55.33.70.8
Bone: stiffness1.92.95.9-1.7-1.7-1.8-1.8-1.8-1.8-1.7-1.8-1.8-1.8-2.3-2.3-2.31.21.11.1-1.12.40.9-0.5
Tibialis anterior weight0.72.43.4-1.7-1.7-1.7-1.6-1.6-1.6-1.7-1.7-1.6-1.6-1.8-1.9-1.91.51.01.0-1.01.81.10.2
Time to tail flick, vehicle, before self-admin1.61.72.81.41.41.41.41.41.41.11.21.41.40.80.80.7-1.7-1.3-1.31.3-0.5-1.5-1.7
Time to tail flick, vehicle, after self-admin0.10.10.9-0.1-0.1-0.2-0.1-0.1-0.1-0.4-0.2-0.1-0.10.10.10.20.30.10.1-0.1-0.60.80.9
Time to tail flick, test, before self-admin0.90.82.60.90.91.01.01.01.00.60.81.01.00.50.40.4-1.2-0.9-0.90.9-0.1-1.1-1.6
Time to tail flick, test, after self-admin0.50.61.10.80.80.90.80.80.80.40.70.80.80.50.50.4-1.0-0.7-0.70.7-0.3-0.7-1.1
Delta time to tail flick, vehicle, before/after SA1.71.73.2-1.3-1.3-1.4-1.3-1.3-1.3-1.3-1.2-1.3-1.3-0.9-0.8-0.71.61.31.3-1.30.31.81.8
Delta time to tail flick, test, before/after SA0.10.10.9-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.0-0.1-0.10.30.30.30.40.10.1-0.1-0.50.41.0
Tibia length0.72.03.01.31.31.41.31.31.31.51.51.41.41.71.71.7-1.0-1.5-1.51.5-1.7-1.00.2
Ambulatory time before self-admin0.10.10.3-0.3-0.3-0.3-0.4-0.4-0.4-0.3-0.3-0.3-0.3-0.4-0.4-0.40.30.40.4-0.40.50.2-0.1
Ambulatory time after self-admin0.60.70.90.90.90.80.80.80.81.00.90.80.80.80.80.8-0.8-0.8-0.80.8-0.7-0.6-0.3
Bone: tissue strength1.51.52.5-1.3-1.3-1.1-1.2-1.2-1.2-1.0-1.1-1.1-1.1-1.4-1.4-1.41.01.41.4-1.41.60.8-0.2
Total heroin consumption2.02.32.91.61.61.71.61.61.61.71.41.61.61.61.61.6-1.5-1.6-1.61.6-1.4-1.1-0.6
Bone: trabecular number2.03.24.61.91.91.81.81.81.81.61.81.81.81.21.21.1-2.1-2.1-2.12.1-0.8-2.1-1.9
Bone: trabecular spacing2.43.16.8-1.8-1.8-1.7-1.7-1.7-1.7-1.6-1.7-1.7-1.7-0.9-0.8-0.72.22.02.0-2.00.12.42.6
Bone: trabecular thickness2.63.111.91.61.61.61.61.61.61.51.61.61.60.30.20.1-2.4-1.9-1.91.90.6-2.7-3.5
Bone: trabecular tissue density3.24.65.6-2.4-2.4-2.2-2.3-2.3-2.3-1.9-2.2-2.2-2.2-1.9-1.9-1.82.42.22.2-2.21.82.21.4
Water consumed over 24 hours0.20.21.1-0.1-0.1-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.7-0.7-0.8-0.2-0.1-0.10.11.0-0.4-1.1
Number of responses in last shaping day0.20.20.30.40.40.50.40.40.40.50.40.40.40.40.40.4-0.4-0.4-0.40.4-0.3-0.4-0.2