Cdc5l

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	IL	gene expression	Cdc5l	0.36	0.12	3.1e-06	0.21	0.19	0.16	0.21	7.3e-06	2.1e-05	9.1e-05	1.0e-05
2	OFC	gene expression	Cdc5l	0.27	0.12	9.4e-05	0.14	0.14	0.16	0.16	2.7e-04	4.2e-04	1.6e-04	1.0e-04
3	Liver	gene expression	Cdc5l	0.1	0.05	1.5e-07	0.03	0.06	0.06	0.05	4.0e-04	7.8e-07	5.1e-07	4.4e-06
4	Brain	mRNA stability	Cdc5l	0.07	0.04	1.0e-04	0.06	0.03	0.03	0.04	3.1e-06	5.7e-04	5.1e-04	1.3e-04
5	NAcc	gene expression	Cdc5l	0.21	0.07	0.0e+00	0.17	0.16	0.18	0.18	2.5e-19	1.3e-17	1.9e-20	3.4e-20
6	PL	gene expression	Cdc5l	0.42	0.13	0.0e+00	0.31	0.29	0.29	0.3	1.1e-34	7.2e-32	5.0e-32	3.5e-33
7	Adipose	gene expression	Cdc5l	0.07	0.03	1.5e-08	0.07	0.07	0.06	0.07	5.7e-08	4.1e-08	4.0e-07	7.5e-08
8	BLA	gene expression	Cdc5l	0.16	0.07	1.9e-07	0.15	0.11	0.12	0.13	1.5e-08	1.3e-06	5.0e-07	1.3e-07
9	pVTA	gene expression	Cdc5l	0.2	0.1	3.1e-05	0.12	0.1	0.08	0.1	1.0e-05	3.4e-05	1.7e-04	5.1e-05
10	Brain	gene expression	Cdc5l	0.15	0.06	5.5e-14	0.16	0.15	0.16	0.17	4.2e-15	8.1e-14	5.2e-15	2.0e-15
11	Liver	mRNA stability	Cdc5l	0.04	0.02	1.3e-04	0.03	0.03	0.01	0.03	3.3e-04	2.5e-04	8.0e-03	4.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11
Bone: apparent density	0.7	1.2	1.7	-1.0	1.0	1.2	-1.1	-1.0	-1.2	1.1	-1.3	-1.2	1.3	-0.5
Area under the delay curve	2.0	2.1	5.6	0.5	-0.2	-2.4	0.5	1.3	1.4	1.7	1.6	0.9	-1.2	-2.3
BMI with tail	2.8	9.1	14.7	3.5	-3.1	-1.6	3.4	2.9	3.1	-3.8	3.2	2.7	-3.1	2.3
BMI without tail	8.1	16.8	32.0	4.1	-3.7	-1.8	4.6	3.8	4.2	-5.7	4.3	3.9	-4.4	3.6
Body weight	0.8	3.3	11.6	1.8	-1.4	0.7	2.1	1.3	1.2	-3.4	1.1	1.0	-1.2	2.9
Weight adjusted by age	0.1	0.2	0.6	0.2	-0.4	-0.5	0.2	0.1	-0.3	0.6	0.1	0.4	-0.1	-0.8
Bone surface	1.9	3.3	7.0	-1.7	1.7	1.1	-1.5	-1.5	-1.8	2.6	-1.9	-1.8	1.9	-1.9
Bone volume	1.3	2.3	4.1	-1.4	1.3	1.0	-1.3	-1.3	-1.5	2.0	-1.7	-1.6	1.7	-1.5
Breakpoint value in progressive ratio session	0.3	0.3	1.3	0.5	-0.3	-1.1	0.0	0.3	0.3	0.6	0.3	0.1	-0.3	-0.8
Number of licking bursts	0.5	0.6	1.6	-0.3	0.5	1.3	0.4	-0.8	-0.8	-0.6	-0.8	-0.7	0.6	1.2
Context. condit. distance diff. score	1.2	1.4	3.4	1.3	-1.6	0.3	1.7	1.0	0.8	-1.8	0.9	1.1	-0.9	0.9
Locomotion velocity, session 1	0.7	0.7	2.7	0.5	-0.4	-1.2	0.7	0.8	0.6	0.9	0.7	0.7	-0.6	-1.6
Locomotion distance, session 1	0.4	0.5	1.1	0.9	-1.0	-0.2	1.1	0.5	0.5	-0.5	0.6	0.7	-0.5	-0.5
Locomotion velocity, session 2	2.8	3.3	8.1	2.0	-1.9	-0.9	2.9	1.7	1.7	-2.0	1.9	1.8	-1.8	0.5
Locomotion distance, session 2	0.9	1.3	1.9	1.4	-1.2	-1.0	1.2	1.1	1.2	-0.7	1.4	1.2	-1.2	-0.5
Locomotion velocity, session 3	1.1	1.2	2.0	1.0	-1.1	-1.4	1.2	1.0	1.2	-0.5	1.3	1.3	-1.2	-0.6
Locomotion distance, session 3	0.4	0.4	0.7	0.4	-0.6	-0.8	0.4	0.7	0.7	0.2	0.7	0.8	-0.7	-0.8
Stereotopy head waving bouts, day 3	0.3	0.4	1.1	-0.4	0.4	1.0	-0.5	-0.5	-0.7	0.0	-0.8	-0.8	0.6	0.4
Stereotopy head waving duration, day 3	0.2	0.2	0.7	0.8	-0.7	-0.2	0.4	0.4	0.3	-0.6	0.3	0.3	-0.4	0.4
Locomotion velocity, session 7	0.3	0.3	1.4	-0.4	0.2	0.2	-0.1	-0.3	-0.3	1.0	-0.3	-0.4	0.5	-1.2
Locomotion distance, session 7	0.6	0.7	1.5	1.0	-0.9	-1.0	0.7	0.7	0.8	0.3	0.9	0.7	-0.7	-1.2
Stereotopy head waving bouts, day 7	0.2	0.3	0.7	0.6	-0.8	0.9	0.4	0.3	0.1	-0.8	-0.0	0.1	-0.2	0.6
Stereotopy head waving duration, day 7	0.3	0.3	1.6	-0.3	0.1	1.3	-0.3	-0.3	-0.5	-0.4	-0.6	-0.5	0.5	0.7
Locomotion velocity, session 8	0.2	0.2	0.8	-0.4	0.0	0.5	-0.1	-0.4	-0.5	0.5	-0.5	-0.4	0.5	-0.9
Locomotion distance, session 8	1.3	1.9	3.3	1.6	-1.8	-0.5	1.8	1.3	1.3	-1.5	1.4	1.5	-1.3	-0.2
Degree of sensitization distance	0.3	0.3	0.6	0.8	-0.6	-0.7	0.8	0.5	0.5	-0.1	0.5	0.4	-0.4	-0.4
Degree of sensitization stereotypy	0.2	0.2	0.4	0.4	-0.6	0.5	0.5	0.5	0.3	-0.4	0.2	0.3	-0.3	0.1
Conditioned locomotion	0.6	0.7	2.8	0.4	-0.2	-1.4	0.2	0.5	0.6	1.1	0.6	0.5	-0.6	-1.7
Cocaine response after cond. corrected	0.7	0.8	3.5	0.1	0.3	0.4	-1.9	-1.1	-1.1	0.3	-1.0	-1.0	1.0	0.3
Cocaine response after cond. not corrected	0.9	1.0	3.8	0.0	0.5	0.3	-1.9	-1.2	-1.2	0.7	-1.1	-1.2	1.1	0.0
Cocaine response before conditioning	0.3	0.3	1.8	-0.2	0.1	-0.6	-0.1	-0.1	-0.1	1.2	-0.1	-0.1	0.1	-1.4
Saline control response	0.1	0.2	0.8	-0.0	-0.1	-0.6	0.5	0.1	0.2	0.6	0.2	0.3	-0.2	-0.9
Bone: connectivity density	1.0	1.5	2.1	-1.4	1.3	1.1	-1.2	-1.1	-1.2	1.5	-1.3	-1.3	1.4	-0.6
Bone: cortical apparent density	0.2	0.3	0.9	-0.8	0.4	1.0	-0.3	-0.1	-0.4	0.7	-0.5	-0.4	0.5	-0.4
Bone: cortical area	0.2	0.2	0.7	0.4	-0.3	0.6	0.6	-0.3	-0.4	0.2	-0.6	-0.4	0.4	-0.8
Bone: cortical porosity	0.8	0.8	1.9	0.4	-0.5	-0.5	1.1	0.8	0.9	-1.4	0.8	1.0	-1.0	1.2
Bone: cortical porosity	0.6	0.7	1.1	0.6	-0.6	-0.9	0.9	0.7	1.0	-1.0	0.8	1.0	-0.9	0.7
Bone: cortical thickness	0.5	0.8	2.4	1.3	-1.2	0.0	1.5	0.8	0.8	-0.9	0.6	0.8	-0.7	-0.3
Bone: cortical thickness	0.4	0.5	1.7	-0.6	0.7	1.3	-0.3	-0.7	-0.7	0.2	-0.9	-0.7	0.7	-0.0
Bone: cortical tissue density	0.2	0.3	0.8	-0.8	0.4	0.9	-0.3	-0.1	-0.4	0.6	-0.5	-0.4	0.5	-0.3
Condit. Reinf. active minus inactive responses	0.9	1.0	2.0	-0.2	0.2	0.6	-0.8	-1.4	-1.4	0.8	-1.3	-1.3	1.3	-0.7
Condit. Reinf. active-inactive response ratio	0.9	0.9	1.7	-0.3	0.4	0.8	-1.1	-1.3	-1.3	0.4	-1.2	-1.3	1.2	0.1
Condit. Reinf. active responses	0.5	0.6	1.5	0.0	-0.0	0.6	-0.3	-1.2	-1.1	0.2	-1.1	-1.0	1.0	-0.4
Condit. Reinf. inactive responses	0.2	0.2	0.7	0.3	-0.5	0.0	0.9	0.1	0.3	-0.9	0.2	0.3	-0.3	0.5
Incentive salience index mean	0.2	0.3	0.7	0.3	-0.3	0.2	0.1	-0.9	-0.7	0.1	-0.6	-0.6	0.6	-0.5
Condit. Reinf. lever presses	0.4	0.6	2.1	0.7	-0.9	-0.3	1.5	0.3	0.5	-1.1	0.6	0.7	-0.6	0.4
Condit. Reinf. active minus inactive responses	0.2	0.3	0.9	0.5	-0.3	-0.2	-1.0	-0.3	-0.4	0.7	-0.4	-0.3	0.4	-0.9
Condit. Reinf. active-inactive response ratio	0.4	0.4	1.7	0.5	-0.3	0.3	-1.3	-0.6	-0.7	0.3	-0.7	-0.6	0.7	-0.3
Condit. Reinf. active responses	0.4	0.5	2.4	0.5	-0.3	-1.0	-0.4	0.4	0.3	1.0	0.3	0.4	-0.3	-1.6
Condit. Reinf. inactive responses	0.6	0.7	2.0	0.1	0.0	-1.1	0.6	0.9	0.9	0.9	0.8	0.9	-0.8	-1.4
Condit. Reinf. lever presses	0.2	0.2	0.4	0.5	-0.4	-0.4	0.6	0.7	0.5	-0.1	0.4	0.5	-0.5	-0.4
Condit. Reinf. lever reinforcers received	0.3	0.4	2.1	0.5	-0.4	-0.9	-0.3	0.3	0.3	0.9	0.3	0.4	-0.2	-1.5
Conditioned reinforcement - actives	0.7	0.7	1.8	1.1	-1.4	-1.1	0.7	0.3	0.2	0.3	0.3	0.7	-0.5	-1.2
Conditioned reinforcement - inactives	0.4	0.4	1.3	1.2	-0.9	-0.9	0.5	0.5	0.3	-0.3	0.4	0.6	-0.6	-0.4
Conditioned locomotion	0.1	0.1	0.2	0.2	-0.5	0.2	0.3	-0.1	-0.4	-0.2	-0.2	0.2	0.2	0.2
Patch foraging indifference point 0 sec	0.7	1.2	2.5	1.0	-1.0	-0.5	0.9	1.6	1.3	-0.6	1.0	1.4	-1.3	0.2
Patch foraging indifference point AUC	3.2	3.7	5.5	2.3	-2.1	-2.4	2.0	1.9	2.0	-0.0	1.8	2.0	-1.9	-1.5
Delay disc. indifference point, 0s delay	1.2	1.3	5.1	0.9	-1.3	-1.1	-1.0	0.8	0.5	1.8	0.8	0.5	-0.3	-2.2
Delay disc. indifference point, 16s delay	0.8	0.8	2.3	-0.6	0.7	-1.3	-0.2	0.6	0.7	1.5	0.8	0.5	-0.5	-1.3
Delay disc. indifference point, 2s delay	1.4	1.5	4.8	0.9	-0.6	-2.2	-0.0	1.0	1.2	1.3	1.4	0.9	-1.1	-1.8
Delay disc. indifference point, 24s delay	1.2	1.2	2.7	0.6	-0.3	-1.3	1.6	1.3	1.3	-0.1	1.2	1.2	-1.2	-0.5
Delay disc. indifference point, 4s delay	2.6	2.8	6.8	1.3	-1.2	-2.6	0.6	1.8	1.8	1.0	2.0	1.6	-1.6	-1.9
Delay disc. indifference point, 8s delay	1.4	1.4	5.9	-0.0	0.2	-1.9	0.1	0.6	0.8	2.0	1.0	0.2	-0.6	-2.4
Indifference point function ln k	0.2	0.3	2.1	-0.4	0.1	0.6	-0.5	0.2	0.1	-0.7	0.1	0.1	-0.0	1.4
Indifference point function log k	0.2	0.3	2.1	-0.4	0.1	0.6	-0.5	0.2	0.1	-0.7	0.1	0.1	-0.0	1.4
Patch foraging total patch changes 0 sec	1.0	1.6	3.4	1.2	-1.2	-0.7	1.1	1.9	1.6	-0.6	1.3	1.6	-1.5	0.2
Patch foraging total patch changes 12 sec	2.8	3.7	6.2	1.9	-1.9	-1.2	2.5	2.4	2.2	-0.9	2.0	2.2	-2.2	-0.5
Patch foraging total patch changes 18 sec	0.5	0.7	1.5	1.1	-0.7	-0.9	0.7	0.9	0.8	0.5	0.6	0.7	-0.7	-1.2
Patch foraging total patch changes 24 sec	2.5	3.0	5.3	1.8	-1.6	-1.4	1.8	2.3	2.0	-0.8	1.9	2.1	-2.0	-0.5
Patch foraging total patch changes 6 sec	2.0	3.0	4.8	1.8	-1.8	-1.1	2.0	2.2	2.0	-1.1	1.7	2.0	-2.0	-0.1
Patch foraging time to switch 0 sec	4.0	6.2	12.0	-3.3	3.5	2.0	-2.4	-2.6	-2.6	1.7	-2.4	-2.6	2.5	-0.0
Patch foraging water rate 0 sec	3.9	6.2	11.9	3.3	-3.4	-1.8	2.7	2.9	2.7	-0.9	2.3	2.7	-2.5	-1.0
Patch foraging water rate 12 sec	4.1	6.3	14.0	3.6	-3.7	-0.9	3.1	2.5	2.3	-2.4	2.2	2.3	-2.2	0.6
Patch foraging water rate 18 sec	1.8	2.4	3.6	1.5	-1.9	-0.5	1.7	1.9	1.7	-1.5	1.6	1.7	-1.6	0.8
Patch foraging water rate 24 sec	2.3	3.2	5.6	2.0	-2.4	-0.0	1.8	1.9	1.9	-2.2	1.6	1.8	-1.6	1.5
Patch foraging water rate 6 sec	1.1	1.5	4.0	1.7	-2.0	-0.6	1.3	1.4	1.3	-0.3	1.1	1.2	-1.0	-0.7
Seeking ratio, delayed vs. immediate footshock	0.0	0.0	0.1	-0.4	0.1	0.1	-0.1	0.0	-0.1	-0.0	-0.1	-0.1	0.1	0.1
Distance traveled before self-admin	0.3	0.3	1.3	0.6	-0.1	0.9	0.3	0.1	0.1	-1.1	0.2	0.1	-0.2	0.9
Distance traveled after self-admin	0.2	0.3	1.0	0.9	-1.0	-0.1	0.3	0.1	0.2	-0.7	-0.1	0.4	-0.3	0.3
Extensor digitorum longus weight	0.1	0.3	1.1	0.5	-0.4	0.7	0.4	0.0	-0.2	-1.1	-0.1	-0.1	0.1	0.8
Bone: elastic displacement	0.3	0.4	1.1	-1.0	0.7	1.0	0.0	-0.5	-0.4	-0.5	-0.3	-0.4	0.4	0.7
Bone: elastic work	1.5	1.9	4.8	-1.7	1.4	2.2	-0.1	-1.3	-1.1	-1.2	-1.0	-1.1	1.1	1.8
Bone: endosteal estimation	1.5	3.3	4.4	-1.8	1.8	1.2	-2.1	-2.0	-2.0	1.7	-2.0	-2.0	2.0	-0.6
Bone: endosteal perimeter	1.2	2.6	3.5	-1.4	1.3	1.0	-1.6	-1.8	-1.8	1.8	-1.9	-1.8	1.8	-1.1
Epididymis fat weight	0.9	2.1	8.3	0.7	-0.7	1.2	1.2	1.0	0.6	-2.9	0.8	0.7	-0.6	2.8
Delta time in closed arm before/after self-admin	0.4	0.4	0.8	0.3	-0.1	-0.4	0.5	0.9	0.8	-0.7	0.7	0.6	-0.7	0.6
Delta time in open arm before/after self-admin	1.4	1.4	2.9	0.6	-1.0	-1.7	0.7	1.0	1.4	0.6	1.5	1.3	-1.3	-1.2
Diff in mean of infusions in LGA sessions	0.5	0.5	1.0	-0.4	0.3	0.5	-0.9	-0.8	-0.8	0.1	-0.9	-1.0	1.0	0.4
Delay discount exponential model param	2.2	2.3	6.2	-0.5	0.2	2.5	-0.8	-1.4	-1.5	-1.6	-1.7	-1.0	1.3	2.3
Extinction: sum of active levers before priming	0.2	0.2	0.7	-0.7	0.3	-0.4	0.1	-0.3	-0.2	0.9	-0.3	-0.0	0.3	-0.8
Active lever presses in extinction session 6	0.3	0.3	0.7	0.6	-0.8	-0.9	0.7	0.3	0.2	-0.4	0.3	0.4	-0.3	-0.1
Bone: final force	0.1	0.2	1.0	0.3	-0.0	1.0	0.3	-0.3	-0.5	-0.4	-0.7	-0.5	0.5	-0.0
Bone: final moment	0.1	0.1	0.6	0.4	-0.3	0.8	0.5	-0.0	-0.2	-0.3	-0.4	-0.2	0.3	-0.2
Food consumed during 24 hour testing period	0.1	0.1	0.2	0.4	-0.4	0.0	0.4	0.4	0.3	-0.0	0.2	0.2	-0.3	-0.0
Glucose	1.3	1.9	4.4	1.9	-1.7	-0.3	1.4	1.3	1.2	-2.1	1.2	1.0	-1.1	1.3
Heart weight	0.8	1.2	2.5	-1.4	1.3	0.8	-1.3	-0.6	-1.0	1.6	-1.0	-0.8	0.8	-0.9
Delay discount hyperbolic model param	2.3	2.5	6.9	-0.6	0.3	2.6	-0.7	-1.4	-1.6	-1.7	-1.7	-1.1	1.4	2.4
Intermittent access intake day 1-15 change	0.5	0.5	1.0	-0.0	0.4	0.6	-0.8	-0.9	-1.0	0.2	-0.9	-0.6	0.9	0.2
Intermittent access intake escalation	1.4	1.4	2.5	-0.8	1.0	1.0	-1.4	-1.4	-1.6	0.6	-1.5	-1.2	1.5	0.1
Intermittent access intake escalation 2	0.1	0.1	0.3	-0.3	0.2	-0.1	0.4	0.0	-0.2	0.5	-0.1	0.4	0.2	-0.6
Intermitt. access day 1 inactive lever presses	1.6	1.7	3.0	-1.0	1.1	1.4	-1.2	-1.7	-1.6	-0.5	-1.4	-1.4	1.4	1.3
Intermitt. access day 15 inactive lever presses	0.2	0.2	0.7	0.3	0.3	0.4	-0.8	-0.1	-0.1	-0.4	0.1	-0.1	0.0	0.8
Intermitt. access escalation Index	0.8	0.7	1.1	0.9	-0.9	-0.3	0.3	0.8	1.0	-1.1	0.9	0.8	-0.8	0.9
Intermittent access day 1 total infusions	0.2	0.2	0.6	-0.0	-0.1	-0.2	0.7	0.2	0.2	-0.8	0.2	0.1	-0.4	0.8
Intermittent access day 15 total infusions	0.7	0.8	1.4	-0.7	0.9	0.8	-0.7	-1.1	-1.2	-0.1	-1.1	-1.0	1.0	0.8
Intermittent access terminal intake (last 3 days)	0.2	0.2	0.5	-0.4	0.4	0.4	0.0	-0.6	-0.7	-0.4	-0.4	-0.5	0.5	0.6
Intermittent access total infusions	0.1	0.1	0.2	-0.0	-0.0	-0.5	0.2	-0.0	0.1	-0.3	0.2	0.1	-0.2	0.5
Intermittent access day 1 locomotion	0.2	0.2	1.2	-0.3	0.1	0.3	0.2	-0.1	-0.1	-0.9	-0.0	-0.1	0.0	1.1
Intermittent access day 15 total locomotion	0.2	0.2	0.6	-0.8	0.8	0.3	0.1	-0.6	-0.5	0.4	-0.5	-0.1	0.5	-0.1
Intermittent access total locomotion	0.2	0.2	0.5	-0.7	0.7	-0.0	-0.3	-0.4	-0.3	0.6	-0.3	-0.2	0.4	-0.3
Intermittent access standard deviation	0.7	0.8	2.0	-1.4	1.3	0.6	-0.4	-0.8	-1.0	0.7	-0.8	-0.6	1.0	-0.2
Left kidney weight	0.7	1.9	3.0	1.1	-1.3	-0.9	1.7	1.7	1.6	-0.8	1.4	1.7	-1.6	0.1
Right kidney weight	1.0	2.9	5.5	1.7	-2.1	-1.1	1.5	2.4	2.0	-0.4	1.8	2.1	-1.9	-0.6
Cocaine induced anxiety	0.5	0.5	1.7	-0.2	0.4	0.3	-1.3	-1.0	-0.7	0.1	-0.7	-1.0	0.7	0.4
Post-drug Anxiety	4.7	5.2	8.9	-2.1	2.5	2.2	-2.6	-2.5	-2.5	0.9	-2.5	-3.0	2.5	0.7
Baseline Anxiety	2.8	3.0	5.3	-2.2	2.3	2.1	-1.0	-1.6	-1.9	1.1	-1.9	-1.9	1.8	-0.2
Tail length	0.7	2.1	7.3	0.8	-0.7	0.5	2.1	1.0	1.1	-2.7	1.0	1.0	-1.2	2.0
Length with tail	0.6	2.3	6.3	-1.4	1.5	2.5	-0.7	-1.2	-1.8	-0.2	-1.9	-1.7	1.7	0.9
Length without tail	4.0	8.8	13.2	-2.7	2.7	2.8	-3.0	-2.9	-3.6	2.3	-3.6	-3.4	3.6	-0.6
Times rat made contact with spout	0.3	0.4	0.7	0.7	-0.4	-0.2	0.8	0.6	0.6	-0.8	0.6	0.5	-0.6	0.7
Lifetime Intake	0.0	0.0	0.2	-0.2	0.1	-0.5	-0.1	-0.1	-0.1	0.1	-0.1	-0.1	0.0	0.1
Liver weight, left	0.7	1.2	1.8	1.2	-1.0	-1.0	1.3	1.1	1.3	-0.7	1.2	1.2	-1.2	-0.2
Liver weight, right	0.5	0.9	1.8	-0.2	0.4	1.1	0.0	-1.3	-0.8	-1.2	-1.1	-0.8	0.8	1.4
Locomotor activity	0.9	1.4	4.6	-1.0	0.8	2.1	0.4	-0.7	-0.9	-1.4	-1.0	-0.9	0.8	1.9
Locomotor testing distance	0.7	1.2	5.8	-0.9	0.6	2.4	0.5	-0.4	-0.7	-1.3	-0.8	-0.8	0.8	1.5
Locomotor testing rearing	0.5	0.8	2.9	0.7	-1.1	1.3	0.9	0.1	0.1	-1.7	0.1	0.0	-0.1	1.2
Locomotion in novel chamber	2.0	2.5	6.2	1.6	-1.2	-2.5	1.6	1.6	1.9	-0.0	1.6	1.6	-1.5	-1.1
Locomotion in novel chamber post-restriction	1.0	1.2	5.4	-0.3	-0.6	-1.7	0.3	0.2	0.2	2.0	0.0	0.7	-0.2	-2.3
Fecal boli incidents, locomotor time 1	0.4	0.5	1.0	0.8	-0.8	-0.7	0.7	0.6	0.7	0.3	0.7	0.4	-0.6	-1.0
Change in fecal boli incidents, locomotor task	0.2	0.2	0.7	-0.4	0.4	-0.8	-0.8	-0.2	-0.3	0.8	-0.1	0.0	0.1	-0.4
Time >=10cm from walls, locomotor time 1	0.2	0.2	0.4	0.5	-0.6	-0.3	0.1	0.4	0.5	0.1	0.4	0.5	-0.5	-0.3
Bouts of movement, locomotor time 1	1.0	1.1	1.7	1.1	-1.3	-1.3	0.9	1.3	1.2	-0.4	1.1	1.2	-1.1	-0.2
Total resting periods, locomotor time 1	0.5	0.5	1.3	1.0	-1.1	-0.6	0.4	0.9	0.7	-0.4	0.6	0.7	-0.6	-0.0
Rest time, locomotor task time 1	1.4	1.5	3.2	1.8	-1.4	-1.7	-0.0	1.2	1.1	0.9	1.2	0.8	-0.9	-1.5
Distance moved, locomotor task time 1	0.2	0.3	1.3	-0.4	-0.1	0.1	0.7	0.0	0.0	-1.1	0.0	0.3	-0.2	0.9
Vertical activity count, locomotor time 1	0.4	0.4	1.3	-1.2	0.8	0.2	0.4	-0.6	-0.5	-0.9	-0.3	-0.1	0.2	1.1
Time >=10cm from walls, locomotor time 2	0.1	0.1	0.3	-0.2	0.2	0.5	-0.5	-0.3	-0.2	-0.1	-0.2	-0.2	0.2	0.4
Bouts of movement, locomotor time 2	1.2	1.3	3.0	0.8	-1.0	-0.3	1.7	1.5	1.5	-0.7	1.4	1.3	-1.1	-0.2
Total resting periods, locomotor time 2	0.9	0.9	2.0	0.6	-0.8	-0.2	1.4	1.3	1.3	-0.6	1.2	1.1	-1.0	-0.0
Rest time, locomotor task time 2	0.5	0.5	1.2	0.9	-0.5	-1.1	-0.1	0.8	0.6	0.7	0.7	0.5	-0.6	-0.9
Distance moved, locomotor task time 2	0.1	0.1	0.3	-0.6	-0.1	0.2	-0.0	-0.4	-0.3	-0.3	-0.4	0.1	0.2	0.2
Vertical activity count, locomotor time 2	0.8	0.8	2.2	-1.5	0.9	0.5	-0.7	-1.2	-1.1	0.7	-1.0	-0.7	0.9	-0.3
Light reinforcement 1	0.2	0.4	0.8	0.2	-0.9	-0.1	0.7	0.5	0.8	-0.9	0.5	0.7	-0.6	0.4
Light reinforcement 2	0.2	0.3	1.0	-0.3	-0.1	0.7	-0.1	-0.4	-0.2	-0.8	-0.5	-0.3	0.4	1.0
Bone: marrow area	1.6	3.4	4.4	-1.9	1.9	1.3	-2.1	-2.0	-2.1	1.8	-2.1	-2.1	2.0	-0.7
Bone: maximum diameter	0.3	0.6	3.0	0.1	-0.1	-0.1	-0.2	-0.4	-0.5	1.4	-0.7	-0.5	0.5	-1.7
Bone: maximum force	0.6	1.0	2.8	-0.7	0.8	1.7	-0.3	-1.1	-1.1	-0.4	-1.3	-1.1	1.1	0.6
Bone: maximum moment	0.4	0.6	2.1	-0.5	0.6	1.5	-0.1	-0.8	-0.8	-0.4	-1.0	-0.8	0.9	0.5
Mean time between licks in bursts	0.9	1.2	2.2	-1.3	1.5	0.0	-1.2	-1.0	-1.2	1.4	-1.2	-1.0	1.1	-0.5
Mean num. licks in bursts	0.8	1.0	2.4	0.7	-0.7	-1.6	-0.0	1.3	1.2	0.3	1.1	1.0	-1.0	-0.9
Cd content in liver	0.5	0.6	1.9	-0.6	0.5	-0.4	-1.0	-0.7	-0.5	1.4	-0.4	-0.5	0.6	-1.1
Co content in liver	0.3	0.3	1.1	0.2	-0.2	-0.5	0.1	-0.0	0.6	-1.0	0.7	0.4	-0.4	1.1
Cu content in liver	0.2	0.2	1.0	0.0	0.1	-0.7	0.0	-0.0	0.1	0.8	0.0	-0.0	0.0	-1.0
Fe content in liver	0.5	0.6	1.5	0.6	-0.5	-0.8	1.2	0.8	0.9	-0.5	0.9	0.8	-0.9	-0.3
K content in liver	2.6	2.6	5.0	-2.2	2.2	2.0	-0.6	-1.6	-1.5	0.1	-1.7	-1.7	1.7	1.1
Mg content in liver	0.2	0.2	0.7	-0.8	0.7	0.5	0.8	-0.0	-0.1	0.1	-0.2	-0.3	0.3	-0.0
Mn content in liver	0.0	0.0	0.3	-0.1	-0.0	-0.1	-0.5	0.2	0.1	0.3	0.0	0.0	-0.0	0.2
Na content in liver	0.3	0.3	2.0	0.2	-0.3	0.4	1.4	0.3	0.4	-0.8	0.3	0.3	-0.3	0.3
Rb content in liver	1.9	2.4	5.4	-2.3	2.2	0.6	-1.1	-1.3	-1.2	1.9	-1.2	-1.5	1.5	-1.2
Se content in liver	1.9	2.4	3.8	1.3	-1.4	-1.7	1.9	1.9	1.6	0.6	1.5	1.5	-1.5	-1.5
Sr content in liver	0.1	0.1	0.4	-0.1	-0.0	0.4	-0.4	-0.6	-0.4	-0.2	-0.4	-0.4	0.3	0.4
Zn content in liver	1.2	1.3	6.3	0.4	-0.5	-1.4	0.7	0.9	0.7	1.7	0.6	0.7	-0.6	-2.5
Bone: minimum diameter	1.1	2.0	3.3	-1.1	1.1	1.1	-1.2	-1.6	-1.7	1.4	-1.8	-1.7	1.7	-1.0
Time in familiar zone, hab. session 1	3.5	3.3	4.8	1.5	-1.8	-1.2	2.0	2.0	2.2	-1.6	2.1	2.1	-2.1	0.5
Time in novel zone, hab. session 1	2.1	2.1	4.0	-1.1	1.3	0.6	-2.0	-1.5	-1.7	1.5	-1.6	-1.6	1.6	-0.5
Total zone transitions, hab. session 1	0.8	1.2	3.2	1.4	-1.3	-0.4	1.8	0.8	0.8	-1.4	0.9	0.9	-0.9	0.4
Total locomotion distance, hab. session 1	0.9	1.2	3.3	1.8	-1.6	-0.4	1.5	0.7	0.7	-1.5	0.7	0.8	-0.9	0.4
Locomotion velocity, hab. session 1	0.6	0.9	2.8	1.7	-1.4	-0.2	1.3	0.3	0.3	-1.4	0.3	0.4	-0.5	0.4
Time in familiar zone, hab. session 2	0.5	0.5	1.4	-1.2	1.1	0.8	-0.3	-0.6	-0.5	-0.3	-0.5	-0.6	0.5	1.0
Time in novel zone, hab. session 2	1.2	1.2	2.9	1.7	-1.6	-1.0	0.7	1.1	1.0	-0.1	1.0	1.1	-1.0	-0.8
Total zone transitions, hab. session 2	0.3	0.4	1.2	-0.1	0.2	1.1	-0.1	-0.6	-0.8	-0.5	-0.7	-0.5	0.6	0.7
Total locomotion distance, hab. session 2	0.2	0.2	0.6	0.4	-0.5	0.6	0.4	-0.2	-0.4	-0.7	-0.3	-0.1	0.2	0.7
Locomotion velocity, hab. session 2	0.1	0.2	0.5	-0.0	-0.1	0.7	0.0	-0.4	-0.6	-0.4	-0.6	-0.3	0.4	0.5
Novel to familiar place preference ratio	0.0	0.0	0.1	-0.1	0.1	0.2	0.1	-0.2	-0.2	-0.2	-0.2	-0.2	0.2	0.3
Novelty place preference	0.1	0.1	0.2	-0.2	0.1	0.3	0.3	-0.1	-0.2	-0.4	-0.2	-0.1	0.1	0.5
Time in novel zone, NPP test	0.1	0.1	0.3	0.2	-0.2	0.1	0.5	0.3	0.2	-0.4	0.2	0.2	-0.2	0.3
Total zone transitions, NPP test	0.5	0.7	2.3	1.0	-1.1	0.1	1.5	0.7	0.6	-1.2	0.7	0.7	-0.6	0.2
Total locomotion distance, NPP test	0.4	0.6	1.4	1.1	-1.2	0.3	1.1	0.4	0.3	-1.2	0.4	0.5	-0.4	0.3
Locomotion velocity, NPP test	0.3	0.5	1.6	0.4	-0.5	1.2	0.7	-0.3	-0.4	-1.3	-0.4	-0.2	0.3	0.7
Intraocular pressure	0.6	0.8	3.2	-0.2	0.5	0.1	-1.8	-1.3	-1.0	0.2	-0.8	-0.9	0.9	0.7
Delta distance traveled before/after self-admin	0.1	0.1	0.7	0.4	-0.9	-0.5	-0.2	-0.2	-0.3	-0.0	-0.5	0.1	0.2	0.0
Delta ambulatory time before/after self-admin	0.3	0.3	1.0	-0.0	-0.4	-0.1	-0.6	-0.8	-0.8	0.3	-1.0	-0.4	0.7	0.1
Parametrial fat weight	2.4	4.7	12.1	2.6	-2.5	0.1	2.3	1.8	1.8	-3.5	1.7	1.6	-1.7	2.4
Pavlov. Cond. lever latency	1.0	1.3	4.1	-0.9	1.2	0.8	-2.0	-1.0	-1.0	0.7	-1.2	-1.2	1.1	0.4
Pavlov. Cond. magazine entry latency	0.5	0.7	1.2	1.0	-1.1	-1.0	0.8	0.7	0.6	0.1	0.7	0.7	-0.7	-0.9
Pavlov. Cond. change in total contacts	0.8	0.9	2.4	1.1	-1.2	-0.9	1.6	0.7	0.7	-0.4	0.8	0.9	-0.9	-0.3
Pavlov. Cond. index score	0.8	1.0	2.8	1.2	-1.4	-0.9	1.7	0.8	0.7	-0.4	0.9	0.9	-0.9	-0.7
Pavlov. Cond. latency score	0.7	0.9	3.0	1.0	-1.2	-0.9	1.7	0.8	0.7	-0.2	0.9	0.9	-0.8	-0.9
Pavlov. Cond. lever contacts	0.9	1.1	3.9	0.9	-1.1	-0.7	2.0	0.9	0.9	-1.1	1.1	1.1	-1.0	0.1
Pavlov. Cond. magazine entry number	0.4	0.5	1.4	-1.2	1.2	0.9	-0.7	-0.4	-0.3	0.1	-0.5	-0.5	0.5	0.7
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.4	-0.2	0.1	-0.1	0.6	0.3	0.4	-0.4	0.2	0.5	-0.4	0.4
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.9	2.1	1.2	-1.3	-0.9	1.5	0.7	0.7	-0.4	0.9	0.9	-0.9	-0.6
Pavlov. Cond. response bias	0.8	1.0	2.1	1.2	-1.3	-0.8	1.5	0.8	0.8	-0.9	1.0	1.0	-1.0	0.0
Pavlov. Cond. lever latency	0.1	0.2	0.4	-0.2	-0.1	-0.6	-0.2	0.5	0.5	0.4	0.5	0.5	-0.5	-0.2
Pavlov. Cond. magazine entry latency	0.3	0.3	1.2	0.9	-0.5	0.5	1.0	0.0	0.0	-1.1	0.2	0.0	-0.0	0.3
Pavlov. Cond. change in total contacts	0.2	0.2	1.0	0.5	-0.1	0.6	0.6	0.1	0.0	-1.0	0.0	0.0	0.0	0.6
Pavlov. Cond. index score	0.4	0.5	1.8	1.0	-0.6	0.5	1.3	0.3	0.2	-1.2	0.2	0.2	-0.3	0.5
Pavlov. Cond. latency score	0.4	0.6	1.9	1.0	-0.7	0.4	1.4	0.4	0.3	-1.3	0.3	0.3	-0.3	0.6
Pavlov. Cond. lever contacts	0.1	0.2	0.6	0.2	0.2	0.7	0.6	-0.2	-0.3	-0.6	-0.4	-0.3	0.3	0.4
Pavlov. Cond. magazine entry number	0.2	0.2	1.1	-0.5	0.1	-0.7	-1.0	0.0	0.1	0.8	0.1	0.1	-0.1	-0.2
Pavlov. Cond. intertrial magazine entries	0.2	0.2	1.0	-0.6	0.4	0.2	-1.0	-0.3	-0.4	0.6	-0.3	-0.4	0.3	0.2
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.5	2.0	0.9	-0.5	0.4	1.4	0.3	0.3	-1.4	0.3	0.3	-0.3	0.7
Pavlov. Cond. response bias	0.2	0.3	0.9	-0.1	0.6	0.9	0.4	-0.4	-0.6	-0.1	-0.6	-0.6	0.6	-0.2
Time in closed arm before self-admin	1.2	1.4	2.8	-0.9	0.9	1.7	-1.6	-1.3	-1.3	0.3	-1.4	-1.2	1.2	0.4
Time in closed arm after self-admin	0.5	0.6	2.2	0.6	-0.2	0.9	-1.1	-0.3	-0.2	-1.1	-0.3	-0.3	0.2	1.5
Time in open arm before self-admin	0.3	0.3	1.3	0.5	-0.5	-0.6	1.1	0.3	0.1	-0.8	0.3	0.1	-0.3	0.1
Time in open arm after self-admin	0.8	0.8	2.8	0.5	-0.8	-1.7	1.1	0.6	0.9	-0.0	1.0	0.9	-0.9	-0.7
Bone: periosteal estimation	0.7	1.5	2.4	-0.8	0.8	0.9	-1.0	-1.4	-1.4	1.3	-1.5	-1.4	1.4	-1.1
Bone: periosteal perimeter	0.8	1.3	2.3	-0.8	0.7	1.4	-0.3	-1.4	-1.4	0.4	-1.5	-1.4	1.4	-0.3
Bone: post-yield work	0.3	0.4	1.0	-0.7	0.5	1.0	-0.1	-0.5	-0.4	-0.5	-0.6	-0.4	0.4	0.9
Progressive ratio test 1 active lever presses	1.2	1.3	2.8	-0.7	0.6	1.2	-1.0	-1.4	-1.1	-1.0	-1.1	-1.3	0.9	1.7
Progressive ratio test 1 breakpoint	1.5	1.5	2.8	-0.9	0.8	1.2	-1.2	-1.6	-1.3	-0.8	-1.2	-1.5	1.1	1.7
Progressive ratio test 1 inactive lever presses	0.3	0.4	1.5	-0.2	0.3	0.8	-0.3	-0.4	-0.5	-0.9	-0.4	-0.5	0.4	1.2
Progressive ratio test 2 active lever presses	0.2	0.2	1.0	0.5	-0.5	-0.0	-0.1	-0.4	-0.3	-1.0	-0.2	-0.0	-0.0	1.0
Progressive ratio test 2 breakpoint	0.3	0.3	1.4	0.7	-0.7	-0.1	0.1	-0.1	-0.0	-1.2	0.1	0.1	-0.2	1.1
Progressive ratio test 2 inactive lever presses	0.6	0.7	1.2	1.1	-1.0	-1.1	0.8	0.8	0.7	-0.5	0.9	0.8	-0.9	-0.1
Incentive Sensitization - Responses	1.8	1.8	3.5	1.9	-1.6	-1.1	1.1	1.3	1.2	-1.4	1.4	1.3	-1.3	0.6
Incentive Sensitization - Breakpoint	1.7	1.7	3.4	1.9	-1.6	-1.2	1.1	1.2	1.2	-1.3	1.4	1.3	-1.3	0.4
Sum of active levers in priming session hrs 5-6	1.9	1.8	8.8	-0.2	0.1	-1.9	0.2	0.4	0.3	2.7	0.2	0.3	-0.2	-3.0
Progressive ratio	2.3	2.7	5.5	-2.3	2.1	2.3	-0.7	-1.3	-1.8	0.8	-1.6	-1.6	1.7	0.0
Food seeking constrained by brief footshock	2.9	3.5	5.1	-2.2	1.9	2.1	-1.5	-2.1	-2.2	0.8	-2.1	-2.1	2.3	0.1
Seeking ratio, punishment vs. effort	0.1	0.2	0.6	0.7	-0.8	-0.8	-0.1	-0.1	0.2	-0.2	0.1	0.2	-0.2	-0.1
Retroperitoneal fat weight	0.9	2.9	5.4	2.3	-2.1	-0.3	1.8	1.7	1.5	-2.3	1.4	1.6	-1.5	1.3
Reaction time number correct	2.8	4.1	6.7	2.0	-2.3	-2.0	1.4	2.6	2.2	0.7	2.0	2.1	-2.1	-2.2
Reaction time mean minus median	1.4	1.9	3.5	-1.5	1.5	1.9	-1.1	-1.5	-1.4	0.2	-1.4	-1.7	1.5	0.6
Reaction time mean minus median AUC	2.1	2.7	4.6	-1.9	1.7	2.1	-1.6	-1.8	-1.7	0.6	-1.7	-2.1	1.8	0.4
Reaction time num false alarms	0.7	1.0	2.0	0.9	-0.7	-1.4	0.5	1.2	1.0	0.4	1.1	1.1	-1.1	-0.9
Reaction time num false alarms AUC	0.9	1.3	2.6	1.0	-0.8	-1.6	0.7	1.5	1.2	0.2	1.4	1.3	-1.3	-0.7
Reaction time trials correct on left	2.8	4.1	6.7	2.0	-2.3	-2.0	1.4	2.6	2.2	0.7	2.0	2.1	-2.1	-2.2
Reaction time trials on left	2.9	4.1	6.7	2.0	-2.3	-2.0	1.4	2.6	2.2	0.6	2.0	2.1	-2.1	-2.1
Reaction time mean	2.5	3.5	6.4	-2.0	2.0	2.5	-1.0	-2.0	-1.8	-0.9	-1.6	-2.0	1.8	2.3
Reaction time mean AUC	2.6	3.5	7.1	-2.0	1.9	2.7	-1.1	-2.0	-1.8	-0.8	-1.7	-2.1	1.9	2.1
Median of all reaction times	2.1	2.9	6.1	-1.8	1.8	2.3	-0.6	-1.8	-1.5	-1.2	-1.3	-1.7	1.5	2.5
Reaction time omissions	0.2	0.3	1.1	-0.2	-0.1	0.7	0.4	-0.1	-0.1	-1.0	-0.1	0.0	-0.0	1.0
Reaction time false alarm rate	0.0	0.1	0.2	-0.2	0.4	-0.4	-0.1	-0.1	-0.1	-0.1	0.2	0.1	-0.0	0.3
Reaction time premature initiation rate	0.1	0.1	0.3	0.4	0.0	-0.2	0.0	0.4	0.3	-0.5	0.2	0.5	-0.4	0.4
Reaction time premature initiations	0.9	1.2	2.6	1.3	-1.1	-0.9	0.7	1.6	1.3	-0.2	1.1	1.4	-1.3	-0.5
Std. dev. reaction times	2.3	3.2	6.3	-1.9	1.9	2.5	-1.2	-1.9	-1.8	-0.6	-1.7	-2.0	1.8	1.7
Reaction time trials completed	2.9	4.1	6.7	2.0	-2.3	-2.0	1.4	2.6	2.2	0.6	2.0	2.1	-2.1	-2.1
Reaction time trials AUC	2.9	4.1	6.8	2.1	-2.4	-1.9	1.4	2.6	2.2	0.5	2.0	2.1	-2.1	-2.0
Run reversals in cocaine runway, females	0.8	0.7	1.5	-0.9	0.3	1.1	-0.3	-1.0	-1.2	0.4	-1.0	-0.7	1.2	-0.1
Run reversals in cocaine runway, males	0.7	0.7	1.3	1.1	-1.0	-0.4	0.5	1.1	1.0	-0.5	0.8	1.1	-1.0	0.1
Latency to leave start box in cocaine runway	1.5	1.6	5.0	-1.0	0.4	2.1	-0.6	-1.2	-1.0	-1.5	-0.9	-0.9	0.9	2.2
Latency to leave start box in cocaine runway, F	1.1	1.2	3.4	-1.4	0.6	1.8	-0.8	-1.2	-1.0	-0.6	-1.1	-0.7	1.0	1.2
Latency to leave start box in cocaine runway, M	0.9	0.8	3.8	0.7	-0.5	0.8	0.5	-0.1	0.1	-2.0	0.2	-0.2	-0.1	1.9
Std. dev. time between licks in bursts	0.4	0.5	1.3	-0.8	0.8	-0.6	-0.6	-0.6	-0.5	1.2	-0.5	-0.3	0.4	-0.9
Total sessions with >9 infusions	0.1	0.1	0.3	0.2	-0.3	-0.3	0.3	0.5	0.4	-0.3	0.3	0.5	-0.3	0.3
Short access day 1 total inactive lever presses	0.7	0.8	1.4	0.9	-1.0	-1.0	0.7	1.1	0.8	-0.2	0.9	1.2	-0.9	-0.3
Short access day 10 total inactive lever presses	0.5	0.6	1.3	0.9	-0.7	-0.6	0.9	0.9	0.8	-0.3	0.8	1.1	-0.7	-0.2
Short access day 1 total infusions	0.5	0.5	1.0	0.9	-0.9	-1.0	0.4	0.7	0.8	-0.4	0.7	0.8	-0.7	-0.0
Short access day 10 total infusions	0.1	0.2	0.4	-0.6	0.4	0.1	-0.2	-0.4	-0.4	-0.1	-0.5	-0.4	0.4	0.6
Short access total infusions	0.0	0.0	0.1	-0.2	0.2	-0.3	-0.3	-0.1	-0.1	0.2	-0.2	-0.1	0.1	0.1
Short access day 1 locomotion	0.2	0.2	0.3	-0.6	0.5	0.2	-0.5	-0.5	-0.5	0.4	-0.5	-0.2	0.5	-0.1
Short access day 10 total locomotion	0.4	0.4	0.7	-0.8	0.9	0.5	-0.2	-0.6	-0.7	0.7	-0.7	-0.5	0.8	-0.5
Short access total locomotion	0.2	0.2	0.7	-0.5	0.4	0.1	-0.2	-0.2	-0.3	0.8	-0.3	-0.0	0.3	-0.7
One hour access (0.3 mA shock)	0.5	0.6	2.8	0.8	-0.7	-1.7	0.5	0.2	0.4	0.4	0.5	0.6	-0.5	-1.2
Compulsive drug intake	0.1	0.1	0.4	0.0	0.1	-0.1	-0.6	0.0	0.2	0.6	-0.0	-0.2	0.2	-0.5
One hour access (shock baseline)	0.1	0.2	0.4	0.4	-0.6	-0.5	0.6	-0.2	-0.1	-0.7	0.1	0.2	-0.1	0.4
Social response proportion	0.3	0.3	1.1	-1.0	0.8	0.0	0.6	-0.6	-0.6	0.5	-0.5	-0.3	0.5	-0.2
Social responses	0.5	0.6	2.6	-1.6	1.4	0.2	0.7	-0.7	-0.6	0.2	-0.6	-0.5	0.6	-0.0
Social time	2.8	3.6	6.3	1.6	-1.8	-2.5	2.2	1.8	2.1	0.0	2.0	2.1	-2.0	-1.7
Soleus weight	0.1	0.3	1.2	0.3	-0.3	0.6	0.7	-0.3	-0.0	-1.1	-0.1	-0.0	0.1	0.7
Bone: stiffness	0.0	0.0	0.1	0.4	-0.1	0.2	0.1	-0.0	-0.1	-0.2	-0.3	-0.1	0.1	0.1
Tibialis anterior weight	0.3	1.1	2.4	1.6	-1.5	-0.3	1.2	1.0	0.8	-1.2	0.8	0.8	-0.9	0.3
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.4	-0.2	0.0	0.6	0.5	0.4	0.2	-0.1	0.3	0.3	0.0	-0.3
Time to tail flick, vehicle, after self-admin	1.2	1.2	2.1	-1.4	1.3	0.8	-0.9	-1.2	-1.1	1.1	-1.1	-1.2	1.1	-0.6
Time to tail flick, test, before self-admin	2.0	1.9	7.1	0.7	-0.3	-2.7	-0.6	0.3	0.6	2.2	0.6	0.3	-0.6	-2.7
Time to tail flick, test, after self-admin	0.1	0.1	0.6	0.8	-0.7	0.0	-0.1	-0.2	0.1	-0.2	-0.0	-0.1	-0.0	-0.4
Delta time to tail flick, vehicle, before/after SA	0.4	0.4	0.8	-0.5	0.6	-0.4	-0.6	-0.8	-0.6	0.9	-0.7	-0.7	0.4	-0.6
Delta time to tail flick, test, before/after SA	1.4	1.3	5.2	0.3	-0.3	1.8	0.7	-0.1	-0.1	-2.3	-0.1	-0.1	0.2	2.2
Tibia length	1.0	2.9	6.4	2.5	-2.4	-1.8	1.8	1.5	1.5	-0.4	1.5	1.7	-1.6	-1.0
Ambulatory time before self-admin	1.0	1.0	2.1	1.4	-0.8	-0.1	1.0	0.9	0.9	-1.5	1.0	0.9	-1.0	0.8
Ambulatory time after self-admin	0.5	0.5	1.9	1.4	-1.2	0.2	0.4	0.1	0.0	-1.1	-0.1	0.4	-0.3	0.6
Bone: tissue strength	0.7	0.7	1.2	0.4	-0.4	-0.6	1.0	1.1	1.0	-0.6	1.1	1.0	-1.0	0.2
Total heroin consumption	0.0	0.0	0.3	-0.1	0.1	-0.2	0.5	0.2	0.1	-0.2	0.1	0.2	-0.0	0.1
Bone: trabecular number	0.5	0.8	1.6	-0.6	0.6	0.9	-0.7	-0.6	-0.9	1.3	-1.0	-1.0	1.0	-1.2
Bone: trabecular spacing	2.2	2.8	4.0	1.6	-1.4	-1.8	2.0	1.8	2.0	-1.1	1.8	2.0	-2.0	0.3
Bone: trabecular thickness	3.0	3.6	5.3	-1.7	1.6	1.3	-2.2	-1.7	-2.1	2.3	-2.1	-2.1	2.1	-1.5
Bone: trabecular tissue density	3.7	5.2	8.5	2.8	-2.8	-2.9	1.1	2.4	2.3	0.4	2.3	2.4	-2.4	-2.0
Water consumed over 24 hours	1.7	2.1	4.9	1.4	-1.4	-0.7	2.2	1.8	1.6	-0.9	1.5	1.6	-1.6	-0.1
Number of responses in last shaping day	0.8	0.8	2.4	1.3	-1.5	-0.8	0.4	0.6	0.9	-0.9	1.0	0.7	-0.8	0.4