Hub : Genes

Cdc42bpb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb mRNA stability Cdc42bpb 0.33 0.24 5.1e-05 0.16 0.16 0.1 0.19 1.0e-04 1.4e-04 2.0e-03 2.8e-05
2 Brain mRNA stability Cdc42bpb 0.29 0.12 0.0e+00 0.37 0.38 0.38 0.38 1.5e-35 3.1e-37 1.9e-37 1.7e-37
3 NAcc gene expression Cdc42bpb 0.03 0.03 6.9e-05 0.03 0.04 0.03 0.03 1.5e-04 3.6e-05 1.7e-04 1.6e-04
4 PL mRNA stability Cdc42bpb 0.07 0.05 2.1e-09 0.08 0.09 0.08 0.08 4.3e-09 8.3e-10 2.3e-09 2.1e-09
5 BLA gene expression Cdc42bpb 0.14 0.09 1.4e-09 0.16 0.17 0.17 0.16 5.3e-09 1.2e-09 3.3e-09 4.8e-09
6 Brain intron excision ratio chr6_130349955_130352949 0.03 0.03 4.0e-03 0.01 0.02 0.02 0.02 1.7e-02 5.7e-03 7.7e-03 7.0e-03
7 Liver mRNA stability Cdc42bpb 0.09 0.09 9.0e-08 0.06 0.06 0.05 0.06 4.9e-07 6.5e-07 1.7e-06 6.7e-07
8 PL gene expression Cdc42bpb 0.1 0.09 7.2e-10 0.1 0.09 0.1 0.09 1.0e-10 3.7e-10 1.0e-10 1.6e-10
9 BLA mRNA stability Cdc42bpb 0.12 0.1 9.9e-05 0.09 0.08 0.06 0.09 1.4e-05 6.9e-05 3.1e-04 1.8e-05
10 NAcc mRNA stability Cdc42bpb 0.09 0.08 1.3e-08 0.07 0.07 0.07 0.07 5.5e-09 7.2e-09 9.9e-09 6.3e-09
11 Adipose gene expression Cdc42bpb 0.08 0.05 2.7e-09 0.07 0.07 0.07 0.07 3.9e-08 4.0e-08 6.2e-08 5.0e-08
12 Brain intron excision ratio chr6_130349955_130350970 0.04 0.05 5.1e-03 0.01 0.01 0.01 0.01 1.5e-02 6.8e-02 1.2e-02 2.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.10.20.60.50.2-0.20.2-0.3-0.3-0.20.2-0.4-0.20.8-0.6
Area under the delay curve0.20.20.40.40.4-0.40.3-0.3-0.3-0.60.60.2-0.5-0.7-0.3
BMI with tail2.16.89.22.62.9-3.02.9-2.8-2.6-3.03.0-1.8-2.80.7-2.0
BMI without tail0.30.71.30.71.1-1.11.1-0.9-0.7-0.80.8-0.1-0.9-0.5-0.0
Body weight0.20.72.3-0.5-0.60.5-0.60.60.70.5-0.51.40.6-1.51.0
Weight adjusted by age0.00.00.2-0.0-0.10.1-0.10.10.10.1-0.10.40.2-0.5-0.2
Bone surface0.00.00.10.20.2-0.10.1-0.1-0.1-0.10.1-0.10.10.4-0.1
Bone volume0.00.10.50.30.2-0.10.2-0.2-0.2-0.10.1-0.4-0.00.7-0.3
Breakpoint value in progressive ratio session0.00.00.10.20.1-0.00.0-0.0-0.1-0.30.3-0.30.00.2-0.2
Number of licking bursts0.30.30.9-0.6-0.30.3-0.30.40.50.6-0.60.40.5-1.00.9
Context. condit. distance diff. score1.41.72.4-1.5-1.51.5-1.51.41.41.2-1.21.01.6-0.61.0
Locomotion velocity, session 10.40.40.9-0.6-0.50.6-0.60.60.60.6-0.60.70.9-0.01.0
Locomotion distance, session 10.40.51.60.80.6-0.60.6-0.6-0.5-0.60.6-0.9-0.41.30.4
Locomotion velocity, session 20.10.10.50.60.1-0.20.2-0.2-0.2-0.30.3-0.5-0.30.70.3
Locomotion distance, session 20.30.51.70.80.6-0.60.6-0.6-0.6-0.60.6-0.9-0.41.30.3
Locomotion velocity, session 30.40.51.50.50.4-0.40.4-0.5-0.6-0.60.6-0.9-0.50.8-1.2
Locomotion distance, session 30.10.10.6-0.2-0.20.2-0.20.10.10.2-0.2-0.10.10.3-0.8
Stereotopy head waving bouts, day 30.10.20.5-0.3-0.40.4-0.40.40.40.3-0.30.10.5-0.70.5
Stereotopy head waving duration, day 30.20.30.9-0.5-0.50.5-0.50.50.50.4-0.40.30.5-0.40.9
Locomotion velocity, session 70.80.92.60.70.6-0.60.6-0.7-0.9-0.80.8-1.1-0.51.6-1.6
Locomotion distance, session 71.11.43.70.91.0-1.01.0-1.1-1.2-1.11.1-1.3-0.81.9-1.6
Stereotopy head waving bouts, day 70.80.91.3-1.1-1.01.0-1.01.00.91.1-1.11.00.9-0.80.1
Stereotopy head waving duration, day 70.30.30.5-0.6-0.60.6-0.60.50.50.6-0.60.60.4-0.7-0.0
Locomotion velocity, session 80.10.10.3-0.2-0.40.4-0.40.40.30.3-0.3-0.00.40.50.4
Locomotion distance, session 80.10.21.50.10.1-0.00.1-0.1-0.1-0.20.2-0.60.11.2-0.0
Degree of sensitization distance0.20.20.40.40.4-0.40.4-0.4-0.4-0.40.4-0.4-0.20.6-0.3
Degree of sensitization stereotypy0.20.20.4-0.6-0.50.5-0.50.40.40.6-0.60.50.4-0.2-0.3
Conditioned locomotion1.01.11.7-1.0-1.31.2-1.21.11.01.3-1.30.91.1-0.50.4
Cocaine response after cond. corrected0.30.30.50.60.7-0.70.7-0.7-0.7-0.20.2-0.5-0.60.6-0.0
Cocaine response after cond. not corrected1.51.62.11.41.4-1.41.4-1.4-1.4-1.21.2-1.3-1.31.1-0.6
Cocaine response before conditioning2.83.44.91.91.8-1.81.7-1.8-1.8-2.22.2-1.9-1.81.3-1.7
Saline control response0.30.41.30.50.5-0.40.5-0.5-0.6-0.30.3-0.8-0.40.7-1.2
Bone: connectivity density0.00.00.10.1-0.20.2-0.20.20.20.1-0.10.10.20.30.1
Bone: cortical apparent density7.59.911.3-3.1-3.43.3-3.43.33.33.1-3.12.93.0-3.02.6
Bone: cortical area1.32.02.7-1.5-1.41.5-1.41.41.41.6-1.61.41.6-1.10.6
Bone: cortical porosity0.10.10.70.2-0.10.0-0.0-0.1-0.20.1-0.1-0.5-0.20.3-0.8
Bone: cortical porosity0.30.40.90.60.4-0.40.5-0.5-0.6-0.30.3-0.9-0.60.6-1.0
Bone: cortical thickness1.11.72.6-1.4-1.41.5-1.41.41.31.6-1.60.91.5-0.60.5
Bone: cortical thickness0.91.01.6-1.1-1.11.1-1.11.11.01.2-1.20.61.1-0.80.2
Bone: cortical tissue density7.710.111.4-3.1-3.43.4-3.43.33.33.1-3.13.03.1-3.12.8
Condit. Reinf. active minus inactive responses0.40.50.60.80.8-0.70.7-0.7-0.7-0.70.7-0.6-0.60.5-0.7
Condit. Reinf. active-inactive response ratio2.32.42.71.61.7-1.61.6-1.6-1.6-1.61.6-1.4-1.61.2-1.4
Condit. Reinf. active responses0.20.30.70.50.5-0.50.5-0.5-0.5-0.50.5-0.5-0.40.8-0.3
Condit. Reinf. inactive responses1.62.03.0-1.4-1.51.5-1.51.51.51.4-1.41.21.4-0.51.7
Incentive salience index mean0.40.50.70.80.7-0.70.7-0.7-0.7-0.80.8-0.6-0.60.7-0.6
Condit. Reinf. lever presses0.20.20.50.70.4-0.40.4-0.4-0.4-0.60.6-0.4-0.30.7-0.3
Condit. Reinf. active minus inactive responses0.30.41.2-0.6-0.60.6-0.60.60.70.5-0.50.50.7-0.51.1
Condit. Reinf. active-inactive response ratio0.40.40.7-0.7-0.60.6-0.60.60.70.5-0.50.70.8-0.80.5
Condit. Reinf. active responses0.00.00.30.20.1-0.10.1-0.1-0.1-0.10.1-0.3-0.10.20.5
Condit. Reinf. inactive responses0.60.81.31.00.8-0.90.9-0.9-0.9-0.60.6-1.0-1.11.0-0.6
Condit. Reinf. lever presses1.72.32.91.61.5-1.61.6-1.5-1.5-1.51.5-1.7-1.51.7-0.7
Condit. Reinf. lever reinforcers received0.00.00.10.20.1-0.20.2-0.2-0.1-0.10.1-0.2-0.20.20.3
Conditioned reinforcement - actives1.71.72.1-1.2-1.51.4-1.41.41.31.5-1.51.21.4-0.81.1
Conditioned reinforcement - inactives0.30.30.4-0.6-0.60.6-0.60.60.60.7-0.70.50.60.10.6
Conditioned locomotion1.11.32.41.50.9-0.90.9-1.0-1.1-0.90.9-1.5-0.91.5-1.2
Patch foraging indifference point 0 sec2.54.04.9-2.1-2.22.2-2.22.12.12.1-2.11.91.8-1.81.4
Patch foraging indifference point AUC2.42.84.4-1.4-1.71.7-1.71.71.81.4-1.41.61.9-1.52.1
Delay disc. indifference point, 0s delay0.10.10.30.0-0.20.2-0.20.20.20.0-0.00.40.1-0.50.2
Delay disc. indifference point, 16s delay0.10.10.30.20.2-0.30.2-0.2-0.1-0.60.60.4-0.3-0.50.0
Delay disc. indifference point, 2s delay0.10.10.20.30.4-0.30.3-0.2-0.2-0.50.5-0.2-0.2-0.1-0.0
Delay disc. indifference point, 24s delay0.10.10.6-0.10.2-0.20.2-0.1-0.0-0.10.10.6-0.3-0.8-0.1
Delay disc. indifference point, 4s delay0.20.21.5-0.1-0.20.2-0.30.30.30.1-0.10.60.1-1.20.2
Delay disc. indifference point, 8s delay0.40.40.70.60.6-0.60.5-0.5-0.5-0.80.80.1-0.7-0.7-0.7
Indifference point function ln k0.50.71.4-0.8-0.90.9-0.80.80.81.2-1.20.80.8-0.70.3
Indifference point function log k0.50.71.4-0.8-0.90.9-0.80.80.81.2-1.20.80.8-0.70.3
Patch foraging total patch changes 0 sec2.74.35.4-2.2-2.32.3-2.32.22.12.1-2.12.01.9-1.81.4
Patch foraging total patch changes 12 sec2.73.54.3-1.8-2.12.0-2.02.02.01.7-1.71.71.9-1.71.9
Patch foraging total patch changes 18 sec0.81.01.8-0.6-1.31.2-1.31.11.10.9-0.90.51.1-0.60.9
Patch foraging total patch changes 24 sec0.10.10.4-0.0-0.30.3-0.30.30.4-0.10.10.40.2-0.50.6
Patch foraging total patch changes 6 sec1.72.53.6-1.5-1.61.5-1.61.61.71.3-1.31.81.3-1.91.9
Patch foraging time to switch 0 sec10.516.117.54.14.2-4.14.1-4.1-4.1-4.24.2-3.7-4.13.2-4.0
Patch foraging water rate 0 sec17.127.429.9-5.4-5.45.5-5.55.45.45.2-5.25.15.2-4.55.0
Patch foraging water rate 12 sec10.015.318.9-4.2-3.83.7-3.73.93.93.8-3.84.23.7-3.74.4
Patch foraging water rate 18 sec5.27.09.2-3.0-2.72.7-2.62.62.62.7-2.73.02.5-2.32.1
Patch foraging water rate 24 sec4.25.97.1-2.7-2.42.4-2.42.52.52.3-2.32.52.4-2.42.3
Patch foraging water rate 6 sec4.26.27.4-2.6-2.72.6-2.62.62.52.7-2.72.22.5-1.52.4
Seeking ratio, delayed vs. immediate footshock0.30.41.3-0.4-0.60.5-0.60.60.60.2-0.20.70.8-0.41.1
Distance traveled before self-admin0.00.00.10.10.2-0.20.2-0.1-0.1-0.10.10.1-0.2-0.10.4
Distance traveled after self-admin0.50.61.0-1.0-0.70.7-0.70.80.80.7-0.70.60.8-0.60.9
Extensor digitorum longus weight5.923.324.8-4.6-4.84.8-4.84.95.04.8-4.84.65.0-5.04.7
Bone: elastic displacement0.60.71.1-0.8-0.90.9-0.90.90.81.0-1.00.40.9-0.80.2
Bone: elastic work0.20.20.4-0.5-0.40.5-0.50.50.50.7-0.70.20.6-0.40.2
Bone: endosteal estimation0.10.20.40.40.7-0.60.6-0.5-0.5-0.60.60.1-0.3-0.2-0.4
Bone: endosteal perimeter0.10.10.7-0.4-0.00.0-0.00.10.20.2-0.20.80.2-0.60.3
Epididymis fat weight4.310.011.33.13.2-3.33.3-3.3-3.3-3.33.3-2.7-3.42.6-3.2
Delta time in closed arm before/after self-admin0.00.00.10.00.2-0.20.2-0.2-0.20.1-0.1-0.2-0.30.2-0.3
Delta time in open arm before/after self-admin0.60.61.4-0.4-0.60.6-0.70.70.70.6-0.61.10.7-1.20.7
Diff in mean of infusions in LGA sessions0.10.10.30.3-0.30.2-0.20.10.00.6-0.6-0.40.10.5-0.2
Delay discount exponential model param0.20.20.6-0.3-0.30.3-0.30.20.20.6-0.6-0.30.40.80.3
Extinction: sum of active levers before priming0.00.00.30.10.0-0.00.0-0.1-0.1-0.00.0-0.50.10.50.1
Active lever presses in extinction session 61.21.11.4-1.0-1.11.1-1.11.11.11.0-1.01.01.2-0.91.1
Bone: final force0.40.61.0-0.8-0.80.9-0.80.80.81.0-1.00.70.9-0.5-0.1
Bone: final moment0.50.81.3-1.0-0.91.0-0.90.90.91.1-1.10.91.0-0.5-0.0
Food consumed during 24 hour testing period0.10.10.4-0.2-0.30.4-0.40.40.40.2-0.20.30.4-0.60.4
Glucose0.60.91.3-1.1-1.11.1-1.21.11.00.8-0.81.11.0-0.50.5
Heart weight0.00.00.20.20.1-0.10.1-0.1-0.10.1-0.1-0.4-0.30.30.0
Delay discount hyperbolic model param0.20.20.5-0.4-0.40.4-0.30.30.20.6-0.6-0.20.40.70.3
Intermittent access intake day 1-15 change1.71.63.31.31.1-1.11.1-1.2-1.2-1.11.1-1.7-1.11.8-1.0
Intermittent access intake escalation2.01.93.81.41.3-1.21.2-1.3-1.3-1.31.3-1.9-1.21.9-1.1
Intermittent access intake escalation 20.20.20.80.30.3-0.30.3-0.3-0.3-0.20.2-0.8-0.20.9-0.3
Intermitt. access day 1 inactive lever presses2.22.42.9-1.6-1.61.7-1.71.71.61.6-1.61.31.6-1.11.4
Intermitt. access day 15 inactive lever presses0.80.81.1-1.0-0.91.0-1.00.90.91.1-1.11.00.9-0.30.7
Intermitt. access escalation Index0.60.52.2-0.6-0.40.5-0.50.60.70.2-0.21.00.4-1.50.9
Intermittent access day 1 total infusions0.40.40.60.80.7-0.70.7-0.7-0.7-0.70.7-0.3-0.70.5-0.5
Intermittent access day 15 total infusions2.02.33.01.61.5-1.51.5-1.5-1.5-1.61.6-1.6-1.51.7-1.1
Intermittent access terminal intake (last 3 days)2.12.33.41.71.5-1.61.6-1.6-1.6-1.31.3-1.6-1.61.9-1.1
Intermittent access total infusions0.91.01.21.11.0-1.01.0-1.0-1.0-1.01.0-0.9-1.01.1-0.8
Intermittent access day 1 locomotion1.11.11.91.41.1-1.01.0-1.1-1.1-1.01.0-1.0-1.00.9-1.0
Intermittent access day 15 total locomotion0.50.51.01.00.6-0.60.6-0.6-0.6-0.60.6-0.9-0.60.9-0.5
Intermittent access total locomotion0.60.71.31.10.8-0.70.7-0.8-0.8-0.80.8-1.1-0.71.0-0.7
Intermittent access standard deviation3.73.95.42.11.9-1.92.0-2.0-2.0-1.81.8-2.2-1.92.3-1.7
Left kidney weight0.61.62.2-1.1-1.31.2-1.21.21.21.5-1.51.31.2-1.21.2
Right kidney weight0.30.81.4-1.2-0.90.8-0.80.80.81.1-1.11.10.7-0.80.8
Cocaine induced anxiety3.13.54.2-2.1-1.81.9-1.91.91.91.9-1.91.91.9-1.91.8
Post-drug Anxiety2.52.83.2-1.8-1.71.7-1.71.71.71.7-1.71.71.7-1.81.4
Baseline Anxiety1.61.72.11.51.2-1.31.3-1.3-1.3-1.31.3-1.1-1.31.2-1.3
Tail length3.39.912.1-3.0-3.23.1-3.13.13.23.4-3.43.23.1-2.43.5
Length with tail3.813.815.8-3.5-4.03.9-3.93.83.84.0-4.03.63.8-2.73.5
Length without tail1.22.74.0-1.3-2.01.9-2.01.81.71.7-1.71.31.7-1.21.1
Times rat made contact with spout0.20.20.5-0.5-0.60.6-0.60.50.50.2-0.20.60.7-0.3-0.1
Lifetime Intake0.50.61.10.90.7-0.70.7-0.7-0.7-0.70.7-0.7-0.71.0-0.6
Liver weight, left4.06.39.3-2.4-2.32.4-2.32.52.52.6-2.62.42.5-2.43.1
Liver weight, right0.00.00.2-0.1-0.10.0-0.00.10.10.2-0.20.4-0.0-0.40.2
Locomotor activity0.00.00.1-0.0-0.30.3-0.30.20.20.2-0.2-0.00.1-0.1-0.3
Locomotor testing distance0.10.20.4-0.3-0.70.7-0.60.50.40.5-0.5-0.10.5-0.1-0.2
Locomotor testing rearing2.13.35.51.91.5-1.51.5-1.7-1.7-1.71.7-2.4-1.82.1-1.9
Locomotion in novel chamber5.56.88.5-2.6-2.52.5-2.52.62.72.6-2.62.62.4-2.92.6
Locomotion in novel chamber post-restriction0.00.00.2-0.00.1-0.20.2-0.1-0.00.1-0.10.3-0.2-0.40.3
Fecal boli incidents, locomotor time 11.11.21.81.21.3-1.31.3-1.2-1.1-1.21.2-1.0-1.00.4-0.5
Change in fecal boli incidents, locomotor task0.10.10.2-0.4-0.40.3-0.30.30.30.4-0.40.30.2-0.40.4
Time >=10cm from walls, locomotor time 10.50.50.70.80.7-0.70.7-0.7-0.7-0.70.7-0.5-0.70.3-0.8
Bouts of movement, locomotor time 11.01.02.20.91.1-1.01.0-1.0-1.0-1.11.1-1.5-0.70.6-0.9
Total resting periods, locomotor time 11.01.11.90.91.2-1.11.1-1.0-1.0-1.11.1-1.4-0.90.6-1.0
Rest time, locomotor task time 10.50.61.5-0.9-0.50.5-0.50.60.70.7-0.71.10.5-1.20.7
Distance moved, locomotor task time 11.01.12.81.00.7-0.60.6-0.8-0.9-1.01.0-1.7-0.91.7-0.9
Vertical activity count, locomotor time 10.30.30.6-0.3-0.70.8-0.80.70.60.3-0.3-0.00.60.10.3
Time >=10cm from walls, locomotor time 20.50.50.8-0.3-0.80.8-0.80.70.70.9-0.90.50.9-0.30.2
Bouts of movement, locomotor time 22.52.74.2-2.0-1.51.5-1.51.61.71.6-1.61.21.7-1.91.6
Total resting periods, locomotor time 22.02.13.9-2.0-1.31.3-1.31.41.51.4-1.41.31.4-1.81.4
Rest time, locomotor task time 20.81.02.9-1.6-0.60.7-0.70.80.80.8-0.81.30.5-1.70.5
Distance moved, locomotor task time 20.91.13.31.40.6-0.50.5-0.7-0.8-0.90.9-1.6-0.61.8-0.9
Vertical activity count, locomotor time 20.30.30.6-0.0-0.70.8-0.70.60.50.6-0.6-0.20.80.70.3
Light reinforcement 10.10.10.2-0.10.2-0.20.2-0.2-0.2-0.50.5-0.0-0.40.4-0.4
Light reinforcement 21.21.52.61.01.4-1.31.3-1.3-1.3-1.21.2-1.0-1.21.0-1.6
Bone: marrow area0.10.20.30.40.6-0.60.6-0.5-0.4-0.50.50.1-0.3-0.3-0.4
Bone: maximum diameter0.20.40.8-0.7-0.40.4-0.40.50.60.6-0.60.80.5-0.90.6
Bone: maximum force0.40.71.0-0.9-0.80.9-0.90.80.81.0-1.00.80.9-0.5-0.3
Bone: maximum moment0.40.71.1-0.9-0.80.9-0.80.80.81.0-1.00.81.0-0.5-0.2
Mean time between licks in bursts0.91.32.21.51.2-1.21.2-1.1-1.1-1.01.0-1.3-1.10.8-1.1
Mean num. licks in bursts0.20.20.90.40.00.0-0.1-0.1-0.2-0.40.4-0.2-0.10.9-0.9
Cd content in liver0.70.83.0-0.8-0.60.7-0.70.80.90.8-0.80.70.7-1.01.7
Co content in liver0.81.02.1-0.8-1.01.0-0.90.91.01.2-1.20.51.1-0.41.5
Cu content in liver0.80.91.31.11.1-1.11.1-1.0-1.0-1.01.0-0.8-1.10.2-0.8
Fe content in liver0.10.10.40.30.4-0.30.3-0.3-0.3-0.30.3-0.0-0.3-0.1-0.6
K content in liver0.10.10.1-0.2-0.40.3-0.30.30.20.3-0.3-0.00.3-0.20.4
Mg content in liver0.00.00.10.0-0.30.2-0.20.20.20.1-0.1-0.20.1-0.20.4
Mn content in liver0.10.11.00.0-0.10.1-0.1-0.1-0.2-0.20.2-0.60.00.4-1.0
Na content in liver0.00.00.10.00.1-0.10.1-0.1-0.1-0.20.2-0.2-0.1-0.1-0.0
Rb content in liver0.50.60.8-0.6-0.90.8-0.80.80.80.9-0.90.80.8-0.80.7
Se content in liver0.10.10.9-0.20.3-0.20.2-0.00.10.0-0.00.6-0.1-0.90.4
Sr content in liver0.60.51.0-0.7-0.50.6-0.60.70.70.7-0.70.90.7-0.71.0
Zn content in liver0.40.41.8-0.6-0.40.5-0.40.50.60.5-0.50.50.6-0.51.3
Bone: minimum diameter0.71.32.2-1.2-1.21.1-1.21.21.11.2-1.21.51.1-1.20.5
Time in familiar zone, hab. session 11.11.13.31.00.8-0.80.8-0.9-1.0-1.01.0-1.3-0.81.8-0.5
Time in novel zone, hab. session 10.10.10.7-0.30.2-0.10.10.00.10.0-0.00.8-0.0-0.90.0
Total zone transitions, hab. session 10.50.71.40.80.9-0.80.8-0.8-0.9-0.90.9-1.0-0.51.2-0.5
Total locomotion distance, hab. session 10.00.00.1-0.2-0.10.2-0.10.10.10.1-0.1-0.10.20.40.2
Locomotion velocity, hab. session 10.30.50.7-0.8-0.80.8-0.70.70.70.7-0.70.40.8-0.20.8
Time in familiar zone, hab. session 21.21.22.21.20.9-0.90.9-1.0-1.0-1.21.2-1.4-1.01.5-1.0
Time in novel zone, hab. session 20.10.10.6-0.30.0-0.00.00.10.20.3-0.30.50.0-0.70.7
Total zone transitions, hab. session 20.60.71.50.90.9-0.80.9-0.8-0.8-0.80.8-1.1-0.61.2-0.1
Total locomotion distance, hab. session 20.50.71.4-0.9-0.80.8-0.80.80.80.9-0.90.30.9-0.31.2
Locomotion velocity, hab. session 20.70.91.5-1.0-0.91.0-0.91.00.91.0-1.00.51.0-0.31.2
Novel to familiar place preference ratio0.20.20.40.40.5-0.50.5-0.5-0.5-0.30.3-0.4-0.50.3-0.6
Novelty place preference0.10.10.20.30.4-0.40.4-0.4-0.4-0.30.3-0.3-0.40.3-0.4
Time in novel zone, NPP test0.10.10.10.20.3-0.30.3-0.3-0.3-0.20.2-0.2-0.30.2-0.4
Total zone transitions, NPP test0.10.20.50.30.3-0.30.4-0.3-0.2-0.20.2-0.5-0.20.70.7
Total locomotion distance, NPP test0.10.10.3-0.5-0.30.3-0.30.30.30.5-0.50.10.20.20.3
Locomotion velocity, NPP test0.10.20.3-0.5-0.30.4-0.30.40.40.5-0.50.10.30.10.5
Intraocular pressure0.10.10.30.30.3-0.30.2-0.3-0.3-0.40.4-0.1-0.40.5-0.6
Delta distance traveled before/after self-admin0.10.10.3-0.3-0.20.2-0.20.10.00.2-0.2-0.50.30.6-0.3
Delta ambulatory time before/after self-admin0.40.40.7-0.8-0.70.8-0.80.70.70.5-0.50.10.9-0.10.3
Parametrial fat weight0.00.10.6-0.1-0.10.0-0.00.10.20.0-0.00.50.2-0.70.4
Pavlov. Cond. lever latency0.70.81.2-1.1-0.90.9-0.90.90.91.0-1.00.91.0-0.90.5
Pavlov. Cond. magazine entry latency0.70.91.41.00.8-0.80.8-0.9-0.9-0.90.9-1.1-0.81.0-1.2
Pavlov. Cond. change in total contacts0.50.51.20.80.6-0.60.6-0.6-0.7-0.80.8-0.8-0.71.1-0.1
Pavlov. Cond. index score0.91.21.51.21.1-1.11.1-1.1-1.1-1.11.1-1.1-1.01.1-0.8
Pavlov. Cond. latency score0.60.71.11.00.8-0.90.9-0.8-0.8-0.90.9-0.9-0.80.9-0.4
Pavlov. Cond. lever contacts0.91.01.51.21.0-1.01.0-1.0-1.0-1.01.0-1.0-1.01.1-0.7
Pavlov. Cond. magazine entry number1.21.51.7-1.3-1.21.2-1.21.21.21.2-1.21.31.2-1.21.2
Pavlov. Cond. intertrial magazine entries5.26.26.8-2.6-2.62.6-2.62.62.52.6-2.62.42.6-2.41.9
Pavlov. Cond. lever-magazine prob. diff.0.60.81.01.00.9-0.90.9-0.9-0.9-0.90.9-0.9-0.81.0-0.7
Pavlov. Cond. response bias1.41.72.11.41.2-1.21.2-1.3-1.3-1.31.3-1.4-1.21.4-1.4
Pavlov. Cond. lever latency2.22.94.6-1.8-1.71.7-1.81.71.71.6-1.62.01.6-2.10.8
Pavlov. Cond. magazine entry latency4.75.46.22.32.5-2.52.4-2.4-2.4-2.42.4-2.1-2.41.9-2.1
Pavlov. Cond. change in total contacts4.05.56.32.42.4-2.52.4-2.5-2.5-2.22.2-2.5-2.42.3-2.0
Pavlov. Cond. index score5.06.47.02.52.6-2.62.6-2.6-2.6-2.62.6-2.5-2.52.5-1.8
Pavlov. Cond. latency score4.96.16.62.52.6-2.62.6-2.6-2.5-2.52.5-2.5-2.52.4-1.8
Pavlov. Cond. lever contacts2.73.75.32.02.0-2.12.1-2.0-1.9-1.81.8-2.3-1.82.3-0.5
Pavlov. Cond. magazine entry number4.04.95.6-2.3-2.32.3-2.32.32.32.2-2.22.12.4-1.72.0
Pavlov. Cond. intertrial magazine entries4.15.47.1-2.3-2.72.6-2.62.52.42.3-2.32.12.5-1.31.8
Pavlov. Cond. lever-magazine prob. diff.5.67.27.82.72.8-2.82.8-2.8-2.8-2.72.7-2.7-2.72.7-2.0
Pavlov. Cond. response bias3.85.16.32.32.4-2.42.4-2.4-2.3-2.12.1-2.5-2.32.4-1.1
Time in closed arm before self-admin2.73.03.61.81.9-1.91.9-1.8-1.8-1.91.9-1.5-1.71.3-1.4
Time in closed arm after self-admin1.41.51.81.21.3-1.41.3-1.3-1.3-1.11.1-0.9-1.31.0-1.2
Time in open arm before self-admin4.85.25.6-2.2-2.42.3-2.32.32.32.3-2.32.12.3-2.12.3
Time in open arm after self-admin3.03.34.6-1.6-1.81.8-1.81.91.91.7-1.72.01.8-2.21.7
Bone: periosteal estimation0.20.51.0-0.7-0.50.6-0.50.70.70.7-0.71.00.8-1.00.4
Bone: periosteal perimeter0.20.30.8-0.7-0.40.4-0.40.50.50.7-0.70.90.6-0.70.4
Bone: post-yield work1.01.41.8-1.4-1.31.3-1.31.21.21.3-1.31.21.2-0.90.5
Progressive ratio test 1 active lever presses0.10.10.30.40.2-0.20.2-0.2-0.2-0.10.1-0.2-0.20.5-0.3
Progressive ratio test 1 breakpoint0.20.20.40.60.3-0.40.4-0.4-0.4-0.30.3-0.4-0.40.7-0.5
Progressive ratio test 1 inactive lever presses2.32.53.1-1.6-1.71.8-1.71.71.61.8-1.81.31.7-0.61.3
Progressive ratio test 2 active lever presses0.00.00.20.20.1-0.10.1-0.2-0.2-0.10.1-0.2-0.20.50.0
Progressive ratio test 2 breakpoint0.00.00.20.20.1-0.10.1-0.1-0.2-0.10.1-0.1-0.20.40.0
Progressive ratio test 2 inactive lever presses0.70.81.3-0.8-0.90.9-0.90.90.90.9-0.90.80.9-0.31.1
Incentive Sensitization - Responses0.00.00.1-0.00.2-0.10.1-0.1-0.1-0.20.20.1-0.20.10.3
Incentive Sensitization - Breakpoint0.00.00.2-0.10.1-0.00.0-0.00.0-0.10.10.2-0.1-0.00.4
Sum of active levers in priming session hrs 5-60.50.51.10.60.5-0.40.4-0.4-0.5-1.11.1-0.8-0.40.7-0.8
Progressive ratio0.40.50.8-0.6-0.70.7-0.70.70.80.5-0.50.60.8-0.80.9
Food seeking constrained by brief footshock1.92.43.0-1.6-1.51.6-1.61.61.51.7-1.71.61.7-0.91.3
Seeking ratio, punishment vs. effort0.10.10.3-0.5-0.30.4-0.40.30.20.5-0.50.30.40.4-0.2
Retroperitoneal fat weight0.10.40.60.50.8-0.80.8-0.7-0.6-0.70.70.0-0.7-0.1-0.4
Reaction time number correct2.33.44.2-1.7-2.02.0-2.01.91.91.9-1.91.61.8-1.31.7
Reaction time mean minus median0.10.10.20.10.3-0.40.4-0.3-0.20.0-0.00.4-0.4-0.3-0.2
Reaction time mean minus median AUC0.10.10.10.00.3-0.30.3-0.3-0.20.1-0.10.4-0.3-0.3-0.3
Reaction time num false alarms0.50.71.0-1.0-1.01.0-1.00.90.90.7-0.70.70.8-0.70.4
Reaction time num false alarms AUC1.01.41.8-1.3-1.31.3-1.31.31.21.1-1.11.11.1-1.00.7
Reaction time trials correct on left2.33.44.2-1.7-2.02.0-2.01.91.91.9-1.91.61.8-1.31.7
Reaction time trials on left2.43.44.2-1.7-2.02.0-2.01.91.92.0-2.01.71.8-1.31.7
Reaction time mean0.60.91.51.11.0-1.11.1-1.1-1.0-0.60.6-0.9-1.20.6-0.4
Reaction time mean AUC0.40.51.00.80.8-0.90.9-0.8-0.8-0.40.4-0.6-1.00.3-0.3
Median of all reaction times0.50.61.11.00.8-0.90.9-0.9-0.9-0.50.5-1.0-1.00.6-0.2
Reaction time omissions1.42.04.3-1.3-1.21.1-1.11.21.31.5-1.51.51.1-1.42.1
Reaction time false alarm rate0.10.10.2-0.4-0.30.3-0.30.30.30.2-0.20.30.2-0.4-0.1
Reaction time premature initiation rate0.60.91.0-1.0-1.01.0-1.01.01.00.8-0.80.81.0-0.81.0
Reaction time premature initiations2.02.83.4-1.6-1.81.8-1.81.71.71.7-1.71.41.7-1.21.6
Std. dev. reaction times0.10.20.40.30.6-0.70.7-0.5-0.5-0.10.10.1-0.6-0.1-0.1
Reaction time trials completed2.43.44.2-1.7-2.02.0-2.01.91.92.0-2.01.71.8-1.31.7
Reaction time trials AUC2.53.64.5-1.8-2.12.0-2.12.01.92.0-2.01.71.9-1.41.8
Run reversals in cocaine runway, females1.11.11.71.01.0-1.01.0-1.1-1.1-1.01.0-0.8-1.20.8-1.3
Run reversals in cocaine runway, males0.90.91.3-0.9-1.11.0-1.01.00.91.2-1.20.91.0-0.70.6
Latency to leave start box in cocaine runway0.20.20.40.30.3-0.40.4-0.5-0.5-0.60.6-0.4-0.60.6-0.5
Latency to leave start box in cocaine runway, F0.30.30.50.60.4-0.50.4-0.5-0.5-0.70.7-0.7-0.60.7-0.4
Latency to leave start box in cocaine runway, M0.10.10.2-0.20.2-0.30.3-0.3-0.3-0.30.3-0.1-0.40.3-0.4
Std. dev. time between licks in bursts0.70.81.61.30.9-0.90.9-0.9-0.9-0.60.6-1.1-0.80.9-0.9
Total sessions with >9 infusions0.30.31.40.80.3-0.30.3-0.4-0.4-0.40.4-1.0-0.21.2-0.4
Short access day 1 total inactive lever presses0.10.10.30.10.3-0.30.3-0.3-0.3-0.40.4-0.5-0.40.5-0.3
Short access day 10 total inactive lever presses0.40.50.7-0.8-0.60.6-0.60.70.70.6-0.60.70.6-0.70.7
Short access day 1 total infusions0.10.10.2-0.3-0.40.4-0.40.40.40.2-0.20.50.4-0.10.5
Short access day 10 total infusions0.50.61.01.00.8-0.70.7-0.8-0.8-0.70.7-0.5-0.80.9-0.9
Short access total infusions0.30.40.80.80.6-0.50.5-0.6-0.6-0.60.6-0.5-0.50.9-0.6
Short access day 1 locomotion1.11.12.21.50.9-0.90.9-1.0-1.0-0.90.9-1.1-1.01.3-1.1
Short access day 10 total locomotion0.91.02.21.50.9-0.80.8-0.9-0.9-0.90.9-1.3-0.90.9-0.8
Short access total locomotion0.20.31.11.10.3-0.30.3-0.4-0.4-0.40.4-0.7-0.30.5-0.4
One hour access (0.3 mA shock)0.00.10.1-0.0-0.20.3-0.20.20.20.3-0.3-0.10.20.20.3
Compulsive drug intake0.00.00.0-0.20.2-0.10.1-0.1-0.1-0.20.20.1-0.20.00.1
One hour access (shock baseline)0.10.10.30.50.2-0.10.2-0.2-0.2-0.20.2-0.6-0.10.5-0.3
Social response proportion0.20.30.6-0.6-0.50.5-0.50.50.50.4-0.40.50.3-0.80.6
Social responses0.10.20.30.10.3-0.20.2-0.3-0.3-0.60.6-0.3-0.40.5-0.5
Social time0.91.21.6-1.2-1.11.0-1.01.11.11.2-1.21.11.0-1.21.0
Soleus weight0.00.10.50.40.2-0.20.2-0.2-0.3-0.10.1-0.4-0.30.7-0.3
Bone: stiffness1.82.93.6-1.9-1.71.8-1.71.71.71.9-1.91.91.8-1.40.7
Tibialis anterior weight0.31.11.8-0.8-1.01.0-1.01.11.11.1-1.11.01.0-1.41.0
Time to tail flick, vehicle, before self-admin0.70.71.0-1.0-0.80.8-0.80.90.90.6-0.61.00.8-0.90.9
Time to tail flick, vehicle, after self-admin0.30.30.60.70.5-0.50.5-0.5-0.6-0.50.5-0.7-0.40.8-0.7
Time to tail flick, test, before self-admin0.00.00.20.0-0.30.2-0.20.20.20.2-0.2-0.00.30.10.4
Time to tail flick, test, after self-admin1.81.92.4-1.3-1.41.3-1.41.31.31.4-1.41.41.5-1.50.9
Delta time to tail flick, vehicle, before/after SA0.30.30.70.70.3-0.30.3-0.4-0.5-0.20.2-0.8-0.30.8-0.8
Delta time to tail flick, test, before/after SA1.21.11.9-1.4-1.01.0-1.01.01.01.1-1.11.20.9-1.30.4
Tibia length0.51.52.2-1.1-1.21.2-1.21.21.21.5-1.51.21.3-1.30.3
Ambulatory time before self-admin0.00.00.10.20.2-0.30.3-0.2-0.20.2-0.20.1-0.3-0.10.2
Ambulatory time after self-admin0.00.00.1-0.10.1-0.10.1-0.1-0.1-0.20.2-0.2-0.00.30.2
Bone: tissue strength0.30.20.5-0.7-0.30.5-0.40.40.40.5-0.50.70.5-0.6-0.4
Total heroin consumption1.01.21.6-1.0-1.21.2-1.21.21.20.9-0.91.01.3-0.90.8
Bone: trabecular number0.00.00.20.2-0.20.2-0.20.10.00.0-0.0-0.1-0.00.4-0.2
Bone: trabecular spacing0.00.00.20.10.1-0.10.2-0.1-0.10.2-0.2-0.00.0-0.4-0.1
Bone: trabecular thickness0.10.10.3-0.3-0.30.4-0.40.40.40.3-0.30.20.3-0.00.6
Bone: trabecular tissue density0.10.20.4-0.4-0.60.5-0.50.40.40.2-0.20.30.3-0.6-0.2
Water consumed over 24 hours2.73.23.9-1.8-1.91.9-2.02.01.91.4-1.41.92.0-1.91.3
Number of responses in last shaping day0.30.30.60.70.5-0.60.6-0.5-0.5-0.50.5-0.4-0.50.1-0.3