Hub : Genes

Cdan1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio XM_008762204.4 0.03 0.02 2.2e-04 0.03 0.02 0.03 0.03 2.9e-05 3.0e-04 9.2e-05 7.7e-05
2 NAcc isoform ratio XM_039106816.2 0.03 0.01 1.4e-03 0.03 0.01 0.02 0.02 9.9e-05 2.9e-03 1.3e-03 8.3e-04
3 Brain isoform ratio XM_008762204.4 0.08 0.04 1.4e-05 0.06 0.04 0.05 0.05 3.2e-06 5.7e-05 2.7e-05 8.9e-06
4 Brain isoform ratio XM_039106816.2 0.06 0.03 9.5e-05 0.04 0.03 0.04 0.04 5.7e-05 3.9e-04 2.1e-04 6.1e-05
5 Brain intron excision ratio chr3_128142492_128142686 0.07 0.04 6.9e-05 0.05 0.04 0.04 0.04 8.3e-06 6.1e-05 4.7e-05 2.0e-04
6 Brain intron excision ratio chr3_128142495_128142686 0.07 0.04 9.1e-05 0.05 0.04 0.04 0.03 1.2e-05 7.3e-05 6.1e-05 3.3e-04
7 pVTA isoform ratio XM_039106816.2 0.05 0.03 9.0e-03 0.03 0.03 0.02 0.03 3.2e-03 1.7e-03 5.3e-03 2.6e-03
8 NAcc intron excision ratio chr3_128142492_128142686 0.02 0.01 5.5e-03 0.01 0.02 0.01 0.01 5.1e-03 7.0e-04 2.1e-03 2.7e-03
9 IC intron excision ratio chr3_128142492_128142686 0.15 0.08 7.5e-04 0.11 0.07 0.06 0.11 3.3e-05 9.8e-04 1.2e-03 3.5e-05
10 IC intron excision ratio chr3_128142495_128142686 0.15 0.08 7.7e-04 0.13 0.06 0.06 0.11 5.4e-06 1.0e-03 1.3e-03 3.1e-05
11 Liver mRNA stability Cdan1 0.03 0.02 1.3e-03 0.03 0.02 0.02 0.02 2.7e-04 1.7e-03 4.2e-03 2.4e-03
12 Adipose gene expression Cdan1 0.2 0.1 1.3e-03 -0 0 0.01 -0 9.5e-01 2.4e-01 7.0e-02 4.0e-01
13 PL isoform ratio XM_008762204.4 0.04 0.02 4.2e-04 0.04 0.03 0.03 0.03 6.0e-05 1.8e-04 1.7e-04 2.0e-04
14 PL isoform ratio XM_039106816.2 0.04 0.02 3.4e-04 0.04 0.03 0.03 0.04 3.4e-05 1.7e-04 1.1e-04 7.1e-05
15 NAcc intron excision ratio chr3_128142495_128142686 0.03 0.02 9.8e-05 0.01 0.02 0.02 0.02 3.5e-02 1.6e-04 5.7e-04 1.2e-03
16 PL intron excision ratio chr3_128142495_128142686 0.03 0.02 2.6e-03 0.01 0.02 0.01 0.01 1.1e-02 2.7e-03 8.2e-03 7.7e-03
17 pVTA gene expression Cdan1 0.07 0.04 8.2e-04 0.04 0.03 0.02 0.02 6.5e-04 4.1e-03 1.6e-02 1.3e-02
18 PL intron excision ratio chr3_128142492_128142686 0.03 0.02 4.9e-03 0.01 0.02 0.01 0.01 1.7e-02 5.3e-03 1.3e-02 1.4e-02
19 Adipose mRNA stability Cdan1 0.11 0.07 6.4e-06 0.02 0.03 0.03 0.03 4.8e-03 4.1e-04 2.2e-04 4.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.50.92.3-1.21.2-1.01.0-1.01.00.7-1.5-1.11.1-0.0-0.4-1.41.40.20.90.5-0.90.2
Area under the delay curve1.51.85.6-1.01.0-1.11.1-1.11.1-0.2-1.9-2.12.12.4-0.6-0.40.4-2.0-1.1-0.61.2-1.1
BMI with tail3.512.220.5-4.04.0-4.34.3-4.34.33.0-4.3-4.54.54.1-3.0-3.23.21.12.3-0.6-2.20.0
BMI without tail4.915.123.2-4.34.3-4.74.7-4.74.73.1-4.7-4.84.84.5-2.8-4.14.11.43.00.2-3.00.9
Body weight4.319.029.7-5.25.2-5.25.2-5.25.24.1-5.3-5.45.45.0-3.2-4.04.01.83.1-1.3-3.00.4
Weight adjusted by age0.60.92.2-0.90.9-1.11.1-1.11.11.0-0.8-1.51.51.3-0.80.1-0.10.30.1-1.3-0.1-0.7
Bone surface1.01.93.8-1.61.6-1.51.5-1.51.51.4-1.4-0.70.7-0.3-1.1-2.02.01.21.70.6-1.70.2
Bone volume1.01.73.3-1.61.6-1.41.4-1.41.41.4-1.4-0.60.6-0.6-1.5-1.81.81.01.50.5-1.5-0.2
Breakpoint value in progressive ratio session0.30.31.2-0.30.3-0.10.1-0.10.10.3-0.20.5-0.5-0.5-1.0-1.01.00.30.71.1-0.70.1
Number of licking bursts0.20.32.50.2-0.20.1-0.10.1-0.1-0.2-0.20.2-0.2-0.3-0.5-1.01.0-0.10.51.6-0.50.4
Context. condit. distance diff. score0.91.12.9-1.01.0-0.80.8-0.80.81.1-0.9-0.30.30.5-1.0-1.71.71.21.60.8-1.60.4
Locomotion velocity, session 14.54.86.92.6-2.62.6-2.62.6-2.6-2.41.81.4-1.4-1.12.12.5-2.5-2.2-2.6-0.42.6-1.1
Locomotion distance, session 12.53.24.82.2-2.22.2-2.22.2-2.2-2.11.40.9-0.9-1.02.11.9-1.9-1.7-2.0-0.12.0-0.4
Locomotion velocity, session 20.70.84.00.4-0.40.5-0.50.5-0.5-1.0-1.0-1.21.21.00.30.3-0.3-2.0-1.30.11.3-0.9
Locomotion distance, session 20.91.23.11.5-1.51.4-1.41.4-1.4-1.60.70.5-0.5-0.81.80.6-0.6-1.1-0.90.90.80.6
Locomotion velocity, session 30.60.73.60.6-0.60.5-0.50.5-0.5-0.6-0.3-0.00.00.7-1.10.4-0.4-1.5-1.10.11.2-1.9
Locomotion distance, session 30.80.83.30.9-0.90.7-0.70.7-0.7-0.40.41.0-1.0-0.5-1.8-0.40.4-0.5-0.11.50.2-1.8
Stereotopy head waving bouts, day 31.82.14.8-1.51.5-1.61.6-1.61.61.2-1.7-1.91.92.2-1.8-0.10.1-0.2-0.2-1.90.2-1.6
Stereotopy head waving duration, day 32.32.77.2-1.61.6-1.71.7-1.71.70.9-2.3-2.62.62.7-1.2-0.20.2-1.0-0.5-1.80.6-1.2
Locomotion velocity, session 70.50.52.70.7-0.70.7-0.70.7-0.7-0.40.40.5-0.5-0.7-1.10.3-0.3-0.6-0.60.50.6-1.7
Locomotion distance, session 70.30.31.50.6-0.60.5-0.50.5-0.5-0.30.70.8-0.8-0.80.0-0.20.20.50.51.2-0.50.4
Stereotopy head waving bouts, day 70.10.21.2-0.10.1-0.10.1-0.10.10.30.10.2-0.20.3-0.70.4-0.4-0.1-0.3-0.70.4-1.1
Stereotopy head waving duration, day 70.30.41.9-0.50.5-0.50.5-0.50.50.8-0.10.1-0.10.2-1.40.3-0.30.3-0.1-1.10.1-1.4
Locomotion velocity, session 80.50.61.9-0.30.3-0.20.2-0.20.2-0.1-1.3-1.31.30.9-0.7-0.20.2-1.2-0.6-0.10.6-1.4
Locomotion distance, session 80.10.21.20.3-0.30.3-0.30.3-0.3-0.2-0.20.0-0.00.10.2-0.80.80.20.51.1-0.50.4
Degree of sensitization distance0.50.63.6-0.40.4-0.40.4-0.40.40.50.50.3-0.3-0.71.30.1-0.11.40.8-0.6-0.81.9
Degree of sensitization stereotypy0.30.30.90.1-0.10.1-0.10.1-0.10.60.81.0-1.0-0.7-0.70.3-0.30.80.3-0.3-0.3-0.7
Conditioned locomotion1.31.63.9-1.41.4-1.31.3-1.31.30.9-1.6-1.51.52.0-0.4-1.51.50.51.10.2-1.10.6
Cocaine response after cond. corrected0.80.94.41.0-1.01.1-1.11.1-1.1-1.40.20.9-0.9-0.40.0-0.30.3-1.2-0.42.10.4-0.2
Cocaine response after cond. not corrected1.21.44.21.4-1.41.4-1.41.4-1.4-1.90.30.8-0.8-0.30.80.1-0.1-1.8-0.92.10.90.0
Cocaine response before conditioning0.91.02.31.0-1.01.0-1.01.0-1.0-1.00.70.1-0.1-0.21.41.5-1.5-1.0-1.3-0.81.3-0.3
Saline control response1.62.15.6-1.91.9-1.71.7-1.71.72.0-1.1-1.51.51.2-1.2-0.10.11.20.6-2.4-0.6-0.5
Bone: connectivity density0.40.71.2-1.11.1-1.11.1-1.11.10.8-1.0-1.01.00.30.1-0.60.60.60.6-0.6-0.60.3
Bone: cortical apparent density0.60.82.5-0.10.10.0-0.00.0-0.00.51.11.5-1.5-1.5-0.3-0.50.51.61.20.8-1.20.9
Bone: cortical area1.21.93.2-1.71.7-1.61.6-1.61.61.5-1.8-1.41.41.0-1.8-1.31.30.50.9-0.5-0.9-0.7
Bone: cortical porosity2.12.26.31.7-1.71.8-1.81.8-1.8-2.30.20.0-0.00.11.70.8-0.8-2.5-1.81.01.8-0.3
Bone: cortical porosity1.11.24.21.0-1.01.2-1.21.2-1.2-1.5-0.2-0.30.30.30.90.7-0.7-2.0-1.50.41.5-0.8
Bone: cortical thickness0.50.82.2-1.01.0-0.90.9-0.90.90.7-1.5-1.31.31.0-1.0-0.80.8-0.30.2-0.4-0.2-0.6
Bone: cortical thickness0.60.72.6-0.70.7-0.60.6-0.60.60.3-1.0-0.10.10.1-0.5-1.61.60.20.91.2-0.90.8
Bone: cortical tissue density0.60.82.2-0.10.1-0.00.0-0.00.00.51.01.5-1.5-1.4-0.3-0.50.51.51.10.7-1.20.9
Condit. Reinf. active minus inactive responses0.80.92.90.0-0.00.2-0.20.2-0.20.91.41.5-1.5-1.7-0.10.8-0.81.70.4-1.1-0.4-0.4
Condit. Reinf. active-inactive response ratio0.60.61.7-0.80.8-0.70.7-0.70.71.30.00.3-0.3-1.1-1.3-0.10.11.20.6-0.8-0.6-1.1
Condit. Reinf. active responses1.51.85.70.5-0.50.7-0.70.7-0.70.82.32.4-2.4-2.30.61.3-1.32.10.4-1.3-0.50.2
Condit. Reinf. inactive responses1.51.85.41.1-1.11.3-1.31.3-1.3-0.22.32.3-2.3-1.71.21.1-1.11.30.2-0.2-0.20.8
Incentive salience index mean1.21.54.30.6-0.60.8-0.80.8-0.80.42.11.9-1.9-2.00.91.5-1.51.50.0-1.2-0.00.2
Condit. Reinf. lever presses0.91.23.50.8-0.80.8-0.80.8-0.8-0.01.91.3-1.3-1.31.51.6-1.61.0-0.2-1.10.20.8
Condit. Reinf. active minus inactive responses1.72.25.4-1.71.7-1.61.6-1.61.61.9-0.6-0.50.50.80.2-1.21.22.32.0-0.7-2.01.8
Condit. Reinf. active-inactive response ratio1.31.54.1-1.31.3-1.21.2-1.21.21.5-0.4-0.20.20.40.1-1.21.22.01.8-0.2-1.81.5
Condit. Reinf. active responses2.12.97.1-2.12.1-1.91.9-1.91.92.4-0.7-0.60.60.7-0.4-1.21.22.72.2-1.1-2.21.6
Condit. Reinf. inactive responses1.21.53.6-1.71.7-1.61.6-1.61.61.9-0.6-0.60.60.5-1.0-0.40.41.61.0-1.7-1.00.2
Condit. Reinf. lever presses1.62.25.3-2.02.0-1.91.9-1.91.92.3-0.9-0.80.80.9-0.9-0.30.31.81.1-2.3-1.10.2
Condit. Reinf. lever reinforcers received1.82.56.9-1.91.9-1.81.8-1.81.82.3-0.5-0.50.50.5-0.1-0.90.92.62.0-1.4-1.91.6
Conditioned reinforcement - actives0.10.20.40.4-0.40.5-0.50.5-0.5-0.60.20.6-0.6-0.50.40.3-0.3-0.7-0.60.10.6-0.4
Conditioned reinforcement - inactives0.20.31.10.2-0.20.4-0.40.4-0.4-0.20.11.0-1.0-0.8-0.4-0.60.60.00.31.0-0.3-0.3
Conditioned locomotion1.11.43.80.9-0.90.6-0.60.6-0.6-1.00.5-0.20.20.31.01.9-1.9-1.4-1.9-1.61.9-1.1
Patch foraging indifference point 0 sec1.52.812.9-2.02.0-1.41.4-1.41.42.1-1.4-1.41.41.6-2.20.8-0.80.2-0.5-3.60.5-2.1
Patch foraging indifference point AUC1.11.64.01.7-1.71.3-1.31.3-1.3-1.22.01.3-1.3-1.40.61.5-1.5-0.4-1.10.11.0-0.3
Delay disc. indifference point, 0s delay0.60.72.2-0.10.1-0.20.2-0.20.2-0.1-0.2-0.70.70.8-0.51.1-1.1-1.1-1.3-1.51.3-1.4
Delay disc. indifference point, 16s delay0.70.84.0-0.20.2-0.00.0-0.00.0-0.7-1.0-0.80.81.1-0.50.2-0.2-2.0-1.4-0.41.4-1.4
Delay disc. indifference point, 2s delay0.50.51.0-0.80.8-1.01.0-1.01.00.7-0.5-0.80.80.7-0.8-0.60.60.60.70.0-0.70.2
Delay disc. indifference point, 24s delay1.01.12.61.0-1.00.8-0.80.8-0.8-1.30.60.3-0.3-0.01.41.3-1.3-1.5-1.6-0.41.6-0.3
Delay disc. indifference point, 4s delay0.80.82.6-0.30.3-0.60.6-0.60.6-0.6-1.1-1.51.51.6-0.0-0.10.1-1.6-0.9-0.11.0-0.6
Delay disc. indifference point, 8s delay3.03.59.2-1.81.8-1.91.9-1.91.90.6-2.7-2.72.73.0-1.8-0.90.9-1.8-0.8-1.00.9-1.8
Indifference point function ln k1.52.76.3-1.91.9-1.61.6-1.61.61.1-2.5-2.02.02.0-1.3-2.12.10.21.30.6-1.20.3
Indifference point function log k1.52.76.3-1.91.9-1.61.6-1.61.61.1-2.5-2.02.02.0-1.3-2.12.10.21.30.6-1.20.3
Patch foraging total patch changes 0 sec1.42.611.3-2.02.0-1.41.4-1.41.42.2-1.4-1.21.21.4-2.40.6-0.60.4-0.3-3.40.4-2.1
Patch foraging total patch changes 12 sec0.50.74.5-0.20.20.1-0.10.1-0.10.90.80.6-0.6-0.8-0.81.2-1.20.7-0.4-2.10.4-1.0
Patch foraging total patch changes 18 sec0.50.81.80.7-0.70.9-0.90.9-0.9-0.11.31.3-1.3-1.0-0.01.2-1.20.3-0.6-0.70.6-0.6
Patch foraging total patch changes 24 sec0.81.43.1-1.51.5-1.41.4-1.41.41.1-1.4-1.71.71.8-0.1-0.20.20.10.1-1.6-0.10.2
Patch foraging total patch changes 6 sec0.40.62.20.1-0.10.2-0.20.2-0.20.60.80.6-0.6-0.8-1.31.1-1.10.3-0.5-1.40.6-1.5
Patch foraging time to switch 0 sec0.20.41.70.1-0.10.3-0.30.3-0.30.40.90.9-0.9-0.60.71.0-1.00.8-0.1-1.30.10.1
Patch foraging water rate 0 sec0.81.74.2-1.51.5-1.31.3-1.31.31.5-1.2-0.60.60.4-2.1-1.61.61.21.60.4-1.5-0.1
Patch foraging water rate 12 sec0.71.45.8-0.50.5-0.70.7-0.70.70.4-0.9-0.10.1-0.1-1.2-2.22.20.61.72.4-1.70.7
Patch foraging water rate 18 sec0.60.92.8-0.70.7-0.60.6-0.60.60.2-1.5-0.80.80.6-1.3-1.71.7-0.40.71.4-0.7-0.1
Patch foraging water rate 24 sec1.42.06.0-1.11.1-0.90.9-0.90.91.5-0.70.5-0.5-0.9-2.5-2.22.21.62.01.4-2.0-0.1
Patch foraging water rate 6 sec0.71.05.50.1-0.10.2-0.20.2-0.20.10.41.0-1.0-1.2-0.9-1.41.41.01.42.3-1.50.9
Seeking ratio, delayed vs. immediate footshock1.01.23.3-0.90.9-1.01.0-1.01.01.1-0.3-0.30.30.2-0.4-1.41.41.81.80.7-1.81.5
Distance traveled before self-admin0.40.61.6-1.01.0-0.60.6-0.60.60.6-1.3-0.80.80.8-0.3-1.01.00.20.70.3-0.70.4
Distance traveled after self-admin0.60.71.6-1.01.0-0.70.7-0.70.71.0-0.60.2-0.2-0.2-0.7-1.21.21.11.30.4-1.20.5
Extensor digitorum longus weight0.10.62.5-0.80.8-0.70.7-0.70.70.6-1.1-0.80.8-0.0-1.6-0.70.7-0.20.20.1-0.2-1.3
Bone: elastic displacement0.40.42.10.4-0.40.5-0.50.5-0.5-0.20.30.1-0.1-0.3-0.50.9-0.9-0.6-0.9-0.70.9-1.5
Bone: elastic work0.60.83.6-1.01.0-0.90.9-0.90.91.2-0.6-0.60.6-0.4-1.90.0-0.00.40.1-1.2-0.1-1.6
Bone: endosteal estimation0.20.51.6-0.50.5-0.50.5-0.50.50.4-0.50.2-0.2-0.8-0.4-1.31.30.71.01.0-1.00.4
Bone: endosteal perimeter0.10.20.4-0.30.3-0.50.5-0.50.50.4-0.10.1-0.1-0.5-0.6-0.60.60.50.60.4-0.6-0.4
Epididymis fat weight0.10.51.5-0.30.3-0.50.5-0.50.5-0.1-1.2-1.21.21.1-0.6-0.30.3-1.0-0.40.00.4-0.9
Delta time in closed arm before/after self-admin0.30.21.00.3-0.30.4-0.40.4-0.4-0.10.50.7-0.7-0.7-0.1-0.20.20.60.51.0-0.50.1
Delta time in open arm before/after self-admin1.61.65.4-1.11.1-0.80.8-0.80.80.9-1.0-0.40.40.2-0.5-2.32.31.21.91.6-1.91.1
Diff in mean of infusions in LGA sessions0.20.30.80.1-0.10.4-0.40.4-0.40.50.70.8-0.8-0.90.10.4-0.40.80.1-0.9-0.1-0.2
Delay discount exponential model param1.21.44.50.7-0.70.9-0.90.9-0.90.41.71.9-1.9-2.10.20.3-0.31.91.10.4-1.10.8
Extinction: sum of active levers before priming0.80.91.31.1-1.11.1-1.11.1-1.1-1.10.80.8-0.8-0.80.30.9-0.9-1.1-1.10.21.1-0.8
Active lever presses in extinction session 60.70.71.60.8-0.81.0-1.01.0-1.0-1.10.3-0.10.1-0.00.70.9-0.9-1.3-1.20.11.2-0.5
Bone: final force0.71.13.1-1.21.2-1.11.1-1.11.11.5-0.5-0.10.1-0.6-1.8-1.01.01.41.3-0.2-1.2-0.5
Bone: final moment0.60.93.3-1.01.0-0.90.9-0.90.91.4-0.40.0-0.0-0.7-1.8-0.90.91.31.2-0.1-1.1-0.6
Food consumed during 24 hour testing period0.20.31.50.1-0.10.1-0.10.1-0.1-0.5-0.2-0.00.00.00.7-0.80.8-0.10.41.2-0.41.1
Glucose0.60.94.4-0.60.6-0.70.7-0.70.70.6-0.8-0.50.50.3-2.1-1.41.40.40.91.2-0.9-0.7
Heart weight3.04.77.6-2.52.5-2.62.6-2.62.61.8-2.7-2.82.82.7-1.4-2.02.00.91.70.1-1.70.6
Delay discount hyperbolic model param1.11.34.20.8-0.81.0-1.01.0-1.00.21.61.8-1.8-2.00.40.4-0.41.60.80.3-0.90.7
Intermittent access intake day 1-15 change0.61.24.8-0.70.7-0.40.4-0.40.40.2-0.9-0.20.20.2-0.5-2.22.20.51.42.2-1.40.9
Intermittent access intake escalation0.81.65.7-1.11.1-0.80.8-0.80.80.6-1.3-0.50.50.6-0.8-2.42.40.71.71.9-1.71.0
Intermittent access intake escalation 21.21.310.00.1-0.10.7-0.70.7-0.7-1.0-0.70.4-0.4-0.30.6-2.02.0-0.60.83.2-0.81.2
Intermitt. access day 1 inactive lever presses0.31.22.1-1.31.3-1.41.4-1.41.41.1-1.2-1.31.31.40.2-0.20.20.60.4-1.4-0.40.2
Intermitt. access day 15 inactive lever presses0.10.30.6-0.30.3-0.70.7-0.70.70.6-0.3-0.40.40.3-0.5-0.60.60.70.70.3-0.7-0.2
Intermitt. access escalation Index1.11.64.1-1.51.5-1.41.4-1.41.41.9-0.3-0.20.20.1-1.6-0.70.72.01.5-0.8-1.50.1
Intermittent access day 1 total infusions0.50.92.80.9-0.90.7-0.70.7-0.7-0.50.70.6-0.6-0.5-0.31.4-1.4-0.8-1.3-1.01.3-1.7
Intermittent access day 15 total infusions0.20.31.4-0.50.5-0.40.4-0.40.40.5-0.5-0.00.00.1-1.2-0.90.90.40.60.6-0.6-0.6
Intermittent access terminal intake (last 3 days)0.30.52.3-0.30.3-0.00.0-0.00.00.1-0.60.3-0.3-0.2-0.9-1.41.40.10.71.5-0.7-0.3
Intermittent access total infusions0.10.10.7-0.00.0-0.00.0-0.00.00.1-0.20.1-0.1-0.1-0.7-0.20.2-0.1-0.00.20.0-0.8
Intermittent access day 1 locomotion0.81.03.4-0.00.0-0.30.3-0.30.3-0.1-0.4-0.90.91.0-0.41.2-1.2-1.2-1.4-1.81.5-1.8
Intermittent access day 15 total locomotion0.20.41.4-0.40.4-0.50.5-0.50.50.0-0.8-0.70.70.6-0.3-1.21.20.00.61.1-0.60.3
Intermittent access total locomotion0.10.20.70.2-0.20.2-0.20.2-0.2-0.5-0.3-0.40.40.40.40.2-0.2-0.8-0.6-0.10.6-0.6
Intermittent access standard deviation0.20.42.6-0.00.00.2-0.20.2-0.2-0.0-0.40.2-0.2-0.2-0.6-1.31.30.10.71.6-0.7-0.1
Left kidney weight0.94.412.4-2.22.2-2.12.1-2.12.11.3-3.2-3.53.53.2-1.3-1.61.6-0.30.7-0.3-0.7-0.6
Right kidney weight1.88.124.2-2.92.9-3.03.0-3.03.01.7-4.2-4.94.94.6-1.3-1.91.9-0.50.7-1.2-0.7-0.5
Cocaine induced anxiety0.50.72.40.2-0.20.5-0.50.5-0.5-0.2-0.1-0.90.90.81.21.1-1.1-0.7-1.1-1.61.1-0.9
Post-drug Anxiety0.30.31.80.0-0.00.1-0.10.1-0.1-0.0-0.2-0.90.90.81.30.4-0.40.0-0.2-0.70.20.3
Baseline Anxiety0.40.51.4-0.30.3-0.70.7-0.70.70.4-0.0-0.10.10.1-0.3-0.80.80.91.00.7-1.01.2
Tail length1.87.19.9-2.92.9-3.13.1-3.13.12.3-3.1-3.03.02.9-1.5-3.13.11.52.60.5-2.51.3
Length with tail1.25.27.7-2.82.8-2.72.7-2.72.72.5-2.6-2.52.52.5-1.8-2.22.21.51.9-0.8-1.90.2
Length without tail0.41.42.6-1.61.6-1.21.2-1.21.21.4-1.6-1.31.31.3-1.2-1.21.20.50.8-0.6-0.8-0.3
Times rat made contact with spout0.40.51.8-0.50.5-0.60.6-0.60.60.4-0.5-0.90.90.7-1.40.2-0.2-0.3-0.4-0.90.4-1.2
Lifetime Intake0.10.10.90.1-0.1-0.00.0-0.00.0-0.1-0.2-0.00.00.1-0.70.0-0.0-0.5-0.4-0.00.4-0.9
Liver weight, left5.79.414.6-3.73.7-3.83.8-3.83.83.0-3.3-3.23.23.1-1.1-2.92.92.22.9-0.7-2.82.0
Liver weight, right2.13.65.7-2.22.2-2.32.3-2.32.31.9-2.3-2.42.42.4-2.4-1.11.10.40.8-1.2-0.7-1.1
Locomotor activity0.30.40.90.5-0.50.8-0.80.8-0.8-0.60.40.3-0.3-0.40.90.8-0.8-0.6-0.8-0.50.80.1
Locomotor testing distance0.61.01.91.0-1.01.2-1.21.2-1.2-0.81.00.7-0.7-0.70.41.4-1.4-0.8-1.2-0.61.2-0.8
Locomotor testing rearing1.02.13.71.6-1.61.9-1.91.9-1.9-1.11.91.7-1.7-1.91.21.2-1.2-0.1-0.70.30.70.0
Locomotion in novel chamber0.40.52.4-0.70.7-0.80.8-0.80.80.8-0.4-0.70.70.7-1.50.2-0.20.20.0-0.90.0-0.7
Locomotion in novel chamber post-restriction3.25.27.5-2.62.6-2.72.7-2.72.71.7-2.5-2.12.12.1-0.4-2.62.61.42.30.6-2.32.3
Fecal boli incidents, locomotor time 11.11.73.01.1-1.11.7-1.71.7-1.7-1.30.81.4-1.4-1.20.70.7-0.7-1.4-1.50.01.5-1.2
Change in fecal boli incidents, locomotor task1.51.52.0-1.21.2-1.41.4-1.41.41.1-1.3-1.41.41.2-0.7-1.31.30.91.30.2-1.30.7
Time >=10cm from walls, locomotor time 10.30.41.00.3-0.30.3-0.30.3-0.3-0.10.31.0-1.0-1.00.4-0.60.60.50.61.0-0.60.5
Bouts of movement, locomotor time 11.71.93.21.8-1.81.4-1.41.4-1.4-1.71.51.4-1.4-1.30.81.3-1.3-1.4-1.50.61.5-0.7
Total resting periods, locomotor time 11.71.93.31.8-1.81.3-1.31.3-1.3-1.61.81.6-1.6-1.50.81.5-1.5-1.0-1.40.51.3-0.5
Rest time, locomotor task time 10.10.10.50.3-0.3-0.30.3-0.30.3-0.10.50.1-0.1-0.10.20.1-0.10.40.30.4-0.30.7
Distance moved, locomotor task time 10.20.31.60.1-0.10.1-0.10.1-0.10.50.40.4-0.4-0.4-1.00.7-0.70.2-0.3-1.30.4-1.2
Vertical activity count, locomotor time 10.20.61.3-1.11.1-0.50.5-0.50.51.1-0.7-0.00.0-0.1-0.3-0.80.81.11.1-0.3-1.10.6
Time >=10cm from walls, locomotor time 24.97.311.8-3.43.4-3.33.3-3.33.33.0-3.0-3.03.02.7-1.4-2.32.31.92.3-1.3-2.20.8
Bouts of movement, locomotor time 21.21.94.1-1.51.5-1.81.8-1.81.81.7-1.0-0.60.60.5-2.0-1.31.31.31.4-0.2-1.40.0
Total resting periods, locomotor time 21.11.94.1-1.51.5-1.81.8-1.81.81.7-0.9-0.60.60.5-2.0-1.21.21.41.5-0.1-1.50.1
Rest time, locomotor task time 23.44.47.52.7-2.72.4-2.42.4-2.4-2.52.62.2-2.2-2.01.91.7-1.7-1.1-1.41.51.40.5
Distance moved, locomotor task time 21.11.33.5-1.41.4-1.31.3-1.31.31.6-1.2-1.21.21.1-0.9-0.40.40.80.5-1.9-0.4-0.7
Vertical activity count, locomotor time 23.04.18.3-2.72.7-2.22.2-2.22.22.9-2.1-1.41.41.3-1.5-1.91.92.22.2-1.1-2.20.5
Light reinforcement 11.12.614.0-1.71.7-1.51.5-1.51.52.60.0-0.50.50.5-1.91.1-1.11.90.3-3.7-0.3-1.9
Light reinforcement 20.50.82.00.6-0.60.8-0.80.8-0.8-0.11.31.4-1.4-1.40.41.2-1.20.5-0.4-0.80.4-0.6
Bone: marrow area0.20.51.5-0.50.5-0.60.6-0.60.60.4-0.50.1-0.1-0.7-0.4-1.21.20.61.00.9-1.00.3
Bone: maximum diameter1.12.13.2-1.81.8-1.81.8-1.81.81.8-1.4-1.01.00.8-1.7-1.41.41.21.4-0.4-1.4-0.3
Bone: maximum force0.91.62.8-1.71.7-1.61.6-1.61.61.7-1.3-1.11.1-0.1-1.6-1.01.01.01.0-0.8-1.0-0.5
Bone: maximum moment0.71.22.5-1.41.4-1.31.3-1.31.31.4-1.1-0.90.9-0.2-1.6-0.80.80.90.9-0.7-0.8-0.6
Mean time between licks in bursts0.41.12.81.2-1.21.1-1.11.1-1.1-1.70.60.3-0.3-0.11.31.0-1.0-1.5-1.30.51.20.1
Mean num. licks in bursts0.30.53.4-0.60.6-0.50.5-0.50.50.7-0.1-0.60.60.5-0.40.8-0.80.2-0.4-1.90.4-0.9
Cd content in liver0.40.41.1-0.90.9-0.70.7-0.70.70.8-0.7-0.50.50.6-1.1-0.60.60.40.6-0.2-0.6-0.1
Co content in liver0.40.51.90.1-0.1-0.10.1-0.10.1-0.5-0.8-1.01.00.9-0.9-0.20.2-1.4-0.70.40.7-1.1
Cu content in liver0.40.51.90.7-0.70.8-0.80.8-0.8-0.70.50.9-0.9-1.10.5-0.40.4-0.10.21.4-0.20.5
Fe content in liver1.01.25.20.1-0.10.1-0.10.1-0.10.61.71.8-1.8-2.30.40.2-0.22.01.0-0.1-1.01.2
K content in liver1.01.02.4-0.70.7-0.90.9-0.90.90.1-1.3-1.41.41.00.3-1.51.5-0.10.81.1-0.81.0
Mg content in liver1.92.06.1-1.21.2-1.31.3-1.31.30.6-1.7-1.01.00.6-1.4-2.52.50.31.41.7-1.40.7
Mn content in liver0.91.02.4-1.11.1-1.21.2-1.21.21.0-1.1-1.51.51.4-1.2-0.40.40.20.3-0.8-0.3-0.3
Na content in liver0.50.64.80.4-0.40.4-0.40.4-0.4-0.60.3-0.00.00.02.2-0.10.10.10.30.8-0.31.9
Rb content in liver1.92.24.7-1.31.3-1.51.5-1.51.50.7-2.2-2.22.21.3-2.2-1.61.6-0.50.50.4-0.5-1.1
Se content in liver0.10.11.10.0-0.00.1-0.10.1-0.10.30.10.4-0.4-0.5-1.0-0.20.20.20.20.2-0.2-0.7
Sr content in liver0.30.30.80.4-0.40.4-0.40.4-0.4-0.60.0-0.10.10.70.90.5-0.5-0.8-0.7-0.20.70.0
Zn content in liver0.91.04.6-0.20.2-0.30.3-0.30.3-0.10.20.4-0.4-0.71.0-1.51.51.01.41.8-1.42.2
Bone: minimum diameter0.61.23.3-1.01.0-1.01.0-1.01.00.5-1.8-1.71.71.7-0.8-0.50.5-0.9-0.4-0.90.4-1.1
Time in familiar zone, hab. session 10.40.41.50.5-0.50.5-0.50.5-0.5-1.00.30.4-0.4-0.81.1-0.10.1-0.5-0.01.20.00.9
Time in novel zone, hab. session 10.90.93.8-1.01.0-0.90.9-0.90.91.5-0.4-0.40.40.9-2.0-0.10.10.90.4-1.4-0.4-1.3
Total zone transitions, hab. session 10.50.75.40.6-0.60.6-0.60.6-0.6-1.10.1-0.10.10.62.30.4-0.4-0.8-0.60.30.61.4
Total locomotion distance, hab. session 10.60.84.70.8-0.80.7-0.70.7-0.7-1.30.2-0.30.30.52.20.8-0.8-1.1-0.90.10.91.0
Locomotion velocity, hab. session 10.81.26.61.0-1.00.9-0.90.9-0.9-1.40.4-0.20.20.52.61.1-1.1-1.2-1.2-0.21.21.1
Time in familiar zone, hab. session 20.40.40.8-0.90.9-0.90.9-0.90.90.7-0.6-0.20.2-0.0-0.7-0.70.70.50.7-0.0-0.70.2
Time in novel zone, hab. session 20.20.21.00.4-0.40.3-0.30.3-0.3-0.10.1-0.20.20.5-0.40.6-0.6-0.4-0.6-0.40.6-1.0
Total zone transitions, hab. session 20.50.73.80.7-0.70.7-0.70.7-0.7-1.4-0.2-0.40.40.32.00.0-0.0-1.2-0.70.80.60.6
Total locomotion distance, hab. session 20.20.21.70.3-0.30.3-0.30.3-0.3-0.7-0.1-0.40.40.11.30.1-0.1-0.5-0.30.20.30.6
Locomotion velocity, hab. session 20.20.32.20.4-0.40.3-0.30.3-0.3-0.7-0.0-0.50.50.21.50.3-0.3-0.5-0.40.10.40.7
Novel to familiar place preference ratio1.11.23.1-1.41.4-1.31.3-1.31.31.5-0.9-1.11.11.5-0.9-0.30.30.80.5-1.8-0.5-0.2
Novelty place preference1.01.12.9-1.31.3-1.11.1-1.11.11.4-0.9-1.11.11.6-0.9-0.10.10.70.4-1.7-0.3-0.3
Time in novel zone, NPP test0.91.02.5-1.21.2-1.11.1-1.11.11.4-0.8-1.01.01.5-1.0-0.20.20.80.4-1.6-0.4-0.3
Total zone transitions, NPP test1.52.15.81.8-1.81.7-1.71.7-1.7-2.40.40.4-0.4-0.32.30.4-0.4-2.0-1.21.91.10.4
Total locomotion distance, NPP test1.41.94.91.6-1.61.5-1.51.5-1.5-2.20.1-0.20.20.21.90.7-0.7-2.2-1.61.11.5-0.1
Locomotion velocity, NPP test1.52.15.71.7-1.71.6-1.61.6-1.6-2.30.1-0.30.30.12.00.9-0.9-2.4-1.71.01.7-0.2
Intraocular pressure0.91.33.20.9-0.90.8-0.80.8-0.8-0.41.21.1-1.1-0.9-0.91.6-1.6-0.7-1.4-1.11.4-1.8
Delta distance traveled before/after self-admin0.10.10.40.0-0.0-0.10.1-0.10.10.20.50.6-0.6-0.6-0.10.2-0.20.40.1-0.4-0.1-0.3
Delta ambulatory time before/after self-admin0.30.31.10.3-0.30.3-0.30.3-0.30.11.00.8-0.8-0.90.30.8-0.80.5-0.1-0.70.1-0.2
Parametrial fat weight0.20.42.00.1-0.10.0-0.00.0-0.00.00.2-0.80.80.70.91.1-1.1-0.1-0.6-1.40.60.0
Pavlov. Cond. lever latency0.70.83.4-1.01.0-0.90.9-0.90.91.0-0.7-0.10.10.4-1.9-1.21.20.60.90.3-0.9-0.5
Pavlov. Cond. magazine entry latency0.40.53.4-0.10.1-0.10.1-0.10.10.80.90.2-0.2-0.30.21.2-1.21.20.1-1.8-0.10.1
Pavlov. Cond. change in total contacts0.20.31.00.6-0.60.4-0.40.4-0.4-0.30.70.4-0.4-0.30.90.2-0.20.60.30.4-0.31.0
Pavlov. Cond. index score0.40.61.80.7-0.70.6-0.60.6-0.6-0.31.00.3-0.3-0.31.21.3-1.30.2-0.6-1.00.50.4
Pavlov. Cond. latency score0.40.62.00.5-0.50.5-0.50.5-0.5-0.30.70.0-0.0-0.01.41.4-1.4-0.0-0.7-1.30.70.5
Pavlov. Cond. lever contacts0.80.94.01.0-1.01.0-1.01.0-1.0-0.80.90.3-0.3-0.42.01.3-1.3-0.4-0.8-0.50.80.8
Pavlov. Cond. magazine entry number0.30.32.20.1-0.10.2-0.20.2-0.2-0.7-0.6-0.00.00.10.1-1.01.0-1.0-0.01.50.00.2
Pavlov. Cond. intertrial magazine entries0.81.02.4-0.70.7-0.70.7-0.70.70.8-0.20.8-0.8-0.9-1.2-1.61.61.11.41.1-1.40.6
Pavlov. Cond. lever-magazine prob. diff.0.70.81.91.0-1.00.9-0.90.9-0.9-0.61.10.6-0.6-0.51.41.4-1.4-0.1-0.7-0.60.70.4
Pavlov. Cond. response bias0.50.61.90.8-0.80.7-0.70.7-0.7-0.21.40.8-0.8-0.90.91.1-1.10.7-0.2-0.40.10.3
Pavlov. Cond. lever latency2.22.97.52.3-2.32.0-2.02.0-2.0-2.71.11.0-1.0-0.81.90.6-0.6-2.1-1.42.31.30.5
Pavlov. Cond. magazine entry latency1.31.66.0-1.41.4-1.31.3-1.31.32.20.20.2-0.2-0.8-1.5-0.20.22.41.4-1.7-1.3-0.3
Pavlov. Cond. change in total contacts1.11.76.9-1.41.4-1.41.4-1.41.42.10.1-0.00.0-0.4-0.6-0.60.62.61.7-1.2-1.71.0
Pavlov. Cond. index score2.12.88.8-1.91.9-1.81.8-1.81.82.8-0.2-0.10.1-0.4-1.8-0.70.73.02.0-1.7-1.90.0
Pavlov. Cond. latency score1.62.17.1-1.61.6-1.61.6-1.61.62.5-0.10.0-0.0-0.5-1.6-0.60.62.71.8-1.4-1.70.0
Pavlov. Cond. lever contacts2.83.89.5-2.62.6-2.42.4-2.42.43.1-1.2-1.11.10.9-2.0-0.80.82.41.6-2.5-1.6-0.3
Pavlov. Cond. magazine entry number1.41.76.91.4-1.41.3-1.31.3-1.3-2.2-0.1-0.30.30.81.30.7-0.7-2.6-1.71.11.7-0.1
Pavlov. Cond. intertrial magazine entries0.40.63.20.2-0.20.1-0.10.1-0.1-0.8-1.0-0.90.91.2-0.30.1-0.1-1.8-1.00.31.0-0.8
Pavlov. Cond. lever-magazine prob. diff.1.92.58.1-1.81.8-1.71.7-1.71.72.7-0.2-0.00.0-0.4-1.7-0.60.62.81.8-1.7-1.80.0
Pavlov. Cond. response bias3.44.712.3-2.82.8-2.52.5-2.52.53.5-1.0-0.80.80.4-2.3-1.01.03.12.2-2.4-2.1-0.1
Time in closed arm before self-admin0.81.02.41.0-1.01.1-1.11.1-1.1-0.41.41.5-1.5-1.50.61.0-1.00.1-0.6-0.80.60.0
Time in closed arm after self-admin0.70.82.70.6-0.60.7-0.70.7-0.70.11.41.6-1.6-1.70.00.6-0.61.00.3-0.0-0.30.3
Time in open arm before self-admin0.70.72.1-0.90.9-1.01.0-1.01.00.6-0.9-1.01.01.1-1.40.0-0.0-0.4-0.2-0.70.3-1.3
Time in open arm after self-admin1.51.64.9-1.31.3-1.01.0-1.01.00.8-1.6-1.01.01.0-1.3-2.22.20.31.31.5-1.30.1
Bone: periosteal estimation0.51.11.9-1.21.2-1.21.2-1.21.21.1-1.3-0.70.70.2-1.4-1.31.30.60.90.0-0.9-0.5
Bone: periosteal perimeter0.60.92.0-1.01.0-1.11.1-1.11.10.9-1.3-1.11.11.0-1.4-0.60.6-0.00.2-0.6-0.2-1.4
Bone: post-yield work0.40.52.30.8-0.80.7-0.70.7-0.7-1.20.2-0.10.1-0.41.5-0.00.0-0.6-0.21.30.21.1
Progressive ratio test 1 active lever presses0.10.10.40.3-0.30.2-0.20.2-0.2-0.00.50.4-0.4-0.4-0.30.5-0.50.0-0.3-0.40.3-0.6
Progressive ratio test 1 breakpoint0.10.10.40.4-0.40.2-0.20.2-0.2-0.20.50.3-0.3-0.4-0.00.6-0.6-0.1-0.4-0.40.4-0.5
Progressive ratio test 1 inactive lever presses0.10.20.60.6-0.6-0.20.2-0.20.20.00.7-0.20.2-0.1-0.60.7-0.70.3-0.2-0.40.2-0.7
Progressive ratio test 2 active lever presses0.10.10.50.0-0.0-0.10.1-0.10.10.40.40.7-0.7-0.6-0.3-0.00.00.70.4-0.2-0.4-0.3
Progressive ratio test 2 breakpoint0.20.20.7-0.20.2-0.30.3-0.30.30.60.20.5-0.5-0.4-0.5-0.20.20.80.5-0.2-0.5-0.2
Progressive ratio test 2 inactive lever presses0.10.10.50.1-0.1-0.10.1-0.10.10.20.20.4-0.4-0.4-0.6-0.10.10.30.20.1-0.2-0.7
Incentive Sensitization - Responses0.00.00.2-0.10.10.1-0.10.1-0.10.1-0.00.3-0.3-0.3-0.3-0.30.30.10.10.1-0.1-0.4
Incentive Sensitization - Breakpoint0.00.10.1-0.20.2-0.00.0-0.00.00.3-0.00.3-0.3-0.2-0.3-0.30.30.20.20.0-0.2-0.4
Sum of active levers in priming session hrs 5-60.40.42.40.6-0.60.7-0.70.7-0.7-0.80.40.5-0.5-0.60.6-0.30.3-0.20.21.5-0.20.9
Progressive ratio0.30.43.3-0.50.5-0.40.4-0.40.40.3-0.2-0.20.20.11.0-0.70.70.70.80.3-0.81.8
Food seeking constrained by brief footshock0.10.10.2-0.10.10.2-0.20.2-0.20.0-0.0-0.20.20.20.10.4-0.4-0.2-0.3-0.50.3-0.4
Seeking ratio, punishment vs. effort0.40.64.10.4-0.40.5-0.50.5-0.5-0.00.50.4-0.4-0.4-1.11.0-1.0-0.4-0.8-0.70.8-2.0
Retroperitoneal fat weight2.410.117.2-3.73.7-4.24.2-4.24.23.8-2.9-3.53.53.5-3.0-1.61.62.22.0-2.7-1.9-0.5
Reaction time number correct1.93.76.8-1.91.9-2.02.0-2.02.01.6-2.2-1.81.81.8-2.0-2.62.61.12.11.1-2.10.7
Reaction time mean minus median0.71.73.2-1.61.6-1.81.8-1.81.81.3-1.4-1.61.61.3-0.9-0.90.90.60.8-0.7-0.80.2
Reaction time mean minus median AUC1.23.04.9-2.02.0-2.22.2-2.22.21.8-1.9-2.22.22.0-1.6-1.21.20.81.0-0.9-1.0-0.2
Reaction time num false alarms0.40.51.00.9-0.90.9-0.90.9-0.9-0.60.70.2-0.2-0.40.51.0-1.0-0.4-0.7-0.20.7-0.3
Reaction time num false alarms AUC0.20.30.60.6-0.60.8-0.80.8-0.8-0.30.80.5-0.5-0.70.40.7-0.70.1-0.2-0.00.2-0.0
Reaction time trials correct on left1.93.76.8-1.91.9-2.02.0-2.02.01.6-2.2-1.81.81.8-2.0-2.62.61.12.11.1-2.10.7
Reaction time trials on left2.03.76.7-1.91.9-2.12.1-2.12.11.6-2.2-1.81.81.8-2.1-2.62.61.12.11.1-2.10.7
Reaction time mean0.30.41.8-0.40.4-0.50.5-0.50.50.80.50.8-0.8-0.9-0.4-0.20.21.30.90.0-0.90.4
Reaction time mean AUC0.30.41.4-0.60.6-0.70.7-0.70.70.90.10.4-0.4-0.6-0.6-0.30.31.20.9-0.1-0.90.2
Median of all reaction times0.50.83.10.4-0.40.4-0.40.4-0.40.21.41.7-1.7-1.80.10.4-0.41.20.60.3-0.60.4
Reaction time omissions0.50.71.9-0.80.8-1.11.1-1.11.11.0-0.6-1.01.01.0-1.00.1-0.10.50.2-1.4-0.2-0.4
Reaction time false alarm rate1.21.73.41.3-1.31.5-1.51.5-1.5-0.91.61.2-1.2-1.31.31.8-1.8-0.4-1.2-0.71.2-0.4
Reaction time premature initiation rate0.50.71.90.4-0.40.0-0.00.0-0.00.31.40.8-0.8-0.91.31.2-1.21.10.1-1.1-0.11.0
Reaction time premature initiations0.40.72.8-0.60.6-1.01.0-1.01.01.10.2-0.10.1-0.10.1-0.20.21.71.2-0.5-1.21.2
Std. dev. reaction times1.22.14.0-1.81.8-2.02.0-2.02.01.8-1.3-1.31.31.1-1.7-0.80.81.01.0-1.1-0.9-0.3
Reaction time trials completed2.03.76.7-1.91.9-2.12.1-2.12.11.6-2.2-1.81.81.8-2.1-2.62.61.12.11.1-2.10.7
Reaction time trials AUC2.14.07.2-2.02.0-2.22.2-2.22.21.8-2.0-1.71.71.6-2.2-2.72.71.52.31.2-2.30.9
Run reversals in cocaine runway, females0.40.43.20.1-0.10.0-0.00.0-0.0-0.5-0.30.2-0.2-0.10.5-1.11.1-0.10.61.8-0.60.9
Run reversals in cocaine runway, males1.51.52.61.6-1.61.5-1.51.5-1.5-1.31.41.3-1.3-1.50.60.8-0.8-0.7-0.90.80.9-0.3
Latency to leave start box in cocaine runway0.20.31.0-0.60.6-0.50.5-0.50.50.60.10.1-0.1-0.00.20.0-0.01.00.8-0.2-0.80.8
Latency to leave start box in cocaine runway, F0.10.11.00.1-0.10.1-0.10.1-0.1-0.50.0-0.10.10.11.00.4-0.4-0.4-0.30.00.30.7
Latency to leave start box in cocaine runway, M1.71.66.9-1.31.3-1.11.1-1.11.12.00.00.2-0.2-0.2-1.0-0.70.72.62.0-0.5-2.00.8
Std. dev. time between licks in bursts0.91.23.9-1.11.1-1.01.0-1.01.00.6-1.6-1.71.72.0-0.9-0.40.4-0.7-0.2-0.90.3-0.9
Total sessions with >9 infusions0.50.62.10.3-0.30.2-0.20.2-0.2-0.50.0-0.20.20.4-0.31.1-1.1-1.2-1.4-1.31.4-1.2
Short access day 1 total inactive lever presses0.60.72.8-0.50.5-0.70.7-0.70.7-0.3-1.4-1.41.41.7-0.1-0.30.3-1.3-0.50.00.6-0.4
Short access day 10 total inactive lever presses0.30.72.4-0.40.4-0.80.8-0.80.80.4-0.5-0.80.80.70.7-0.80.80.91.20.8-1.21.6
Short access day 1 total infusions0.50.72.70.8-0.80.7-0.70.7-0.7-1.20.10.1-0.10.10.30.8-0.8-1.6-1.4-0.01.4-0.8
Short access day 10 total infusions0.10.10.7-0.10.1-0.20.2-0.20.20.00.0-0.30.30.30.00.6-0.6-0.2-0.4-0.90.4-0.3
Short access total infusions0.20.20.7-0.10.1-0.40.4-0.40.4-0.1-0.4-0.40.40.5-0.90.3-0.3-0.8-0.6-0.50.6-0.8
Short access day 1 locomotion0.91.12.61.0-1.00.8-0.80.8-0.8-0.80.91.0-1.0-0.80.31.6-1.6-1.0-1.4-0.91.4-1.0
Short access day 10 total locomotion0.71.36.60.5-0.50.6-0.60.6-0.6-1.5-1.0-1.21.21.30.40.4-0.4-2.6-1.70.31.7-1.1
Short access total locomotion0.91.13.10.2-0.20.1-0.10.1-0.1-0.5-0.5-0.80.81.00.21.4-1.4-1.7-1.7-1.61.8-1.5
One hour access (0.3 mA shock)1.11.25.40.1-0.10.5-0.50.5-0.50.10.21.5-1.5-1.5-0.3-1.61.61.01.42.3-1.40.6
Compulsive drug intake1.31.53.9-1.21.2-0.90.9-0.90.91.1-0.90.0-0.0-0.2-1.4-2.02.01.21.81.5-1.80.7
One hour access (shock baseline)0.40.51.40.7-0.70.8-0.80.8-0.8-0.31.01.2-1.2-1.00.60.7-0.70.2-0.3-0.20.3-0.4
Social response proportion1.41.68.9-0.70.7-0.90.9-0.90.91.70.90.6-0.6-0.8-0.2-0.40.43.02.0-0.3-2.11.6
Social responses1.21.57.5-0.10.1-0.20.2-0.20.21.51.91.8-1.8-2.0-1.00.5-0.52.71.3-0.9-1.30.1
Social time0.71.03.0-1.01.0-1.01.0-1.01.01.4-0.10.4-0.4-0.4-0.9-0.90.91.71.4-0.2-1.40.6
Soleus weight0.20.72.3-0.80.8-0.80.8-0.80.81.20.00.4-0.4-0.5-1.0-0.70.71.51.30.1-1.30.3
Bone: stiffness0.60.91.7-1.31.3-1.21.2-1.21.21.2-1.0-0.80.80.1-0.6-0.90.91.01.0-0.5-1.00.3
Tibialis anterior weight0.62.15.7-1.51.5-1.41.4-1.41.41.9-0.30.5-0.5-1.0-1.5-1.61.62.42.20.3-2.20.7
Time to tail flick, vehicle, before self-admin0.60.62.3-0.20.2-0.40.4-0.40.4-0.2-0.8-1.51.51.50.30.2-0.2-1.0-0.8-1.10.8-0.3
Time to tail flick, vehicle, after self-admin0.30.41.3-0.70.7-0.50.5-0.50.50.4-1.0-0.40.40.3-0.7-1.11.1-0.20.30.1-0.3-0.4
Time to tail flick, test, before self-admin0.20.31.2-0.40.4-0.50.5-0.50.50.4-0.1-0.70.70.7-0.20.4-0.40.1-0.2-1.10.2-0.4
Time to tail flick, test, after self-admin0.70.71.4-1.11.1-0.90.9-0.90.90.8-1.0-1.11.11.2-0.5-0.70.70.40.5-0.6-0.50.5
Delta time to tail flick, vehicle, before/after SA1.51.43.7-1.31.3-1.01.0-1.01.01.3-1.00.1-0.1-0.1-1.3-1.91.91.31.70.9-1.70.3
Delta time to tail flick, test, before/after SA0.00.00.2-0.30.3-0.10.1-0.10.10.2-0.3-0.00.00.1-0.1-0.40.40.10.2-0.0-0.20.4
Tibia length0.41.04.6-0.40.4-0.50.5-0.50.50.2-0.7-1.61.60.9-0.01.2-1.2-0.8-1.1-2.21.1-1.2
Ambulatory time before self-admin0.30.41.4-0.90.9-0.50.5-0.50.50.5-1.2-0.90.90.9-0.4-0.70.7-0.10.3-0.0-0.3-0.0
Ambulatory time after self-admin0.20.31.0-0.10.10.3-0.30.3-0.30.30.51.0-1.0-1.0-0.2-0.20.20.70.50.4-0.60.1
Bone: tissue strength0.20.20.50.3-0.30.4-0.40.4-0.4-0.5-0.1-0.60.6-0.30.30.5-0.5-0.7-0.6-0.10.6-0.4
Total heroin consumption1.01.22.81.1-1.11.4-1.41.4-1.4-1.70.20.4-0.4-0.31.10.5-0.5-1.7-1.11.21.10.0
Bone: trabecular number1.22.04.7-1.51.5-1.51.5-1.51.51.1-1.7-1.11.10.1-0.8-2.22.20.91.71.2-1.70.8
Bone: trabecular spacing1.11.55.40.6-0.60.8-0.80.8-0.8-0.11.20.6-0.6-0.1-0.32.1-2.1-0.5-1.6-2.31.6-1.6
Bone: trabecular thickness0.60.82.1-0.30.3-0.20.2-0.20.20.3-0.10.8-0.8-1.20.2-1.41.40.91.31.4-1.31.0
Bone: trabecular tissue density2.53.610.42.1-2.12.2-2.22.2-2.2-2.41.32.0-2.0-1.02.8-0.40.4-0.8-0.13.20.02.3
Water consumed over 24 hours0.20.31.0-0.00.00.1-0.10.1-0.10.50.60.8-0.8-1.0-0.80.0-0.00.80.50.1-0.5-0.2
Number of responses in last shaping day0.60.73.00.6-0.60.0-0.00.0-0.0-0.10.70.2-0.2-0.1-1.11.3-1.3-0.5-1.1-1.11.1-1.7