Hub : Genes

Ccdc39

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA mRNA stability Ccdc39 0.09 0.07 9.0e-04 0.08 0.09 0.06 0.07 1.9e-04 8.8e-05 1.5e-03 4.2e-04
2 PL mRNA stability Ccdc39 0.2 0.09 0.0e+00 0.26 0.27 0.26 0.27 3.4e-28 4.7e-30 7.0e-28 7.3e-30
3 OFC mRNA stability Ccdc39 0.24 0.13 8.5e-04 0.11 0.08 0.12 0.09 1.2e-03 6.0e-03 7.6e-04 3.1e-03
4 NAcc intron excision ratio chr2_116688917_116690264 0.04 0.02 9.2e-06 0.02 0.04 0.02 0.03 8.0e-04 6.9e-06 1.2e-03 1.7e-04
5 NAcc mRNA stability Ccdc39 0.16 0.07 0.0e+00 0.2 0.18 0.18 0.19 5.0e-23 2.5e-20 4.0e-20 8.6e-22
6 NAcc gene expression Ccdc39 0.06 0.04 1.4e-04 0.04 0.02 0.03 0.04 1.3e-05 1.5e-03 1.7e-04 3.6e-05
7 BLA mRNA stability Ccdc39 0.46 0.14 0.0e+00 0.36 0.43 0.44 0.44 3.1e-20 1.1e-24 1.4e-25 1.5e-25
8 IL gene expression Ccdc39 0.17 0.1 7.9e-03 0.12 0.08 0.09 0.08 6.9e-04 6.5e-03 4.1e-03 5.3e-03
9 RMTg mRNA stability Ccdc39 0.2 0.13 1.7e-03 0.07 0.09 0.13 0.12 6.1e-03 1.8e-03 2.2e-04 3.2e-04
10 IL mRNA stability Ccdc39 0.38 0.15 1.1e-06 0.17 0.23 0.2 0.21 6.4e-05 2.9e-06 1.7e-05 7.8e-06
11 Brain gene expression Ccdc39 0.14 0.07 2.1e-10 0.1 0.09 0.09 0.09 9.8e-10 5.9e-09 2.1e-08 6.6e-09
12 PL alternative polyA NM_001415040.1 0.05 0.03 1.2e-05 0.05 0.04 0.04 0.04 5.6e-06 1.8e-05 1.9e-05 2.2e-05
13 BLA gene expression Ccdc39 0.08 0.05 2.4e-03 0.06 0.06 0.05 0.05 2.3e-04 5.0e-04 1.1e-03 8.8e-04
14 PL alternative polyA XM_017590856.2 0.05 0.03 4.7e-05 0.04 0.03 0.04 0.04 1.9e-05 1.2e-04 3.9e-05 3.3e-05
15 PL gene expression Ccdc39 0.13 0.07 7.0e-11 0.07 0.08 0.07 0.1 1.5e-08 4.7e-09 4.7e-08 9.3e-11
16 IL intron excision ratio chr2_116688917_116690264 0.15 0.1 9.7e-03 0.13 0.07 0.1 0.12 6.4e-04 1.0e-02 2.3e-03 9.3e-04
17 Adipose gene expression Ccdc39 0.05 0.04 3.0e-03 0.01 0 0.01 0.01 9.6e-03 9.0e-02 8.0e-03 1.4e-02
18 Brain mRNA stability Ccdc39 0.48 0.23 0.0e+00 0.17 0.17 0.18 0.17 2.4e-15 4.7e-16 1.7e-16 5.9e-16
19 Brain intron excision ratio chr2_116692622_116695324 0.07 0.04 7.9e-05 0.04 0.04 0.03 0.04 1.4e-04 9.8e-05 4.4e-04 1.3e-04
20 Brain intron excision ratio chr2_116690367_116692431 0.09 0.06 2.0e-06 0.06 0.07 0.05 0.06 7.9e-06 7.1e-07 2.2e-05 2.9e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density2.13.67.9-2.8-2.82.6-2.62.80.62.70.81.7-2.4-1.51.6-1.5-1.20.31.8-1.21.5-0.90.9
Area under the delay curve0.70.71.7-1.3-1.11.1-0.91.21.20.91.1-0.8-1.1-0.1-0.1-0.0-0.0-0.60.0-0.30.3-1.01.0
BMI with tail1.03.36.7-1.4-1.71.5-2.01.7-1.52.1-1.31.2-1.0-2.42.6-2.6-2.21.92.3-2.50.61.1-1.1
BMI without tail1.32.65.2-2.1-2.22.1-2.22.20.12.30.21.8-1.8-1.61.7-1.6-1.40.71.5-1.31.8-0.30.3
Body weight0.31.32.7-0.2-0.3-0.0-0.60.7-1.30.8-1.2-0.00.3-1.41.6-1.6-1.21.31.4-1.6-0.71.6-1.6
Weight adjusted by age0.70.81.71.31.3-1.21.3-1.3-0.2-1.3-0.1-0.21.20.7-0.80.70.7-0.4-0.50.9-1.10.4-0.4
Bone surface0.10.10.3-0.5-0.50.5-0.50.50.00.60.10.4-0.5-0.30.2-0.3-0.30.10.5-0.30.0-0.30.3
Bone volume0.30.51.6-1.1-1.00.9-0.91.30.51.10.70.5-0.8-0.40.4-0.4-0.0-0.20.6-0.10.1-0.30.3
Breakpoint value in progressive ratio session3.94.38.0-1.8-2.11.9-2.52.3-1.12.6-1.51.8-1.6-2.42.8-2.5-2.52.22.4-2.81.70.6-0.6
Number of licking bursts1.72.03.8-1.3-1.51.3-1.71.6-0.71.7-0.71.3-1.0-1.92.0-1.8-1.51.31.9-1.80.20.6-0.6
Context. condit. distance diff. score2.32.78.3-2.6-2.42.1-1.92.92.02.32.00.7-2.0-0.80.6-0.60.2-0.81.00.11.8-1.11.0
Locomotion velocity, session 11.81.95.01.31.1-1.20.5-1.0-2.2-0.5-2.21.21.3-0.91.2-1.2-1.22.01.1-1.3-0.51.9-1.8
Locomotion distance, session 11.31.75.10.80.5-0.5-0.1-0.5-2.2-0.1-2.31.10.7-1.41.4-1.4-1.62.01.2-1.7-0.51.5-1.5
Locomotion velocity, session 23.54.19.61.81.4-1.70.7-0.9-2.8-0.6-3.11.62.0-2.01.8-1.9-1.52.51.8-1.4-2.03.1-3.1
Locomotion distance, session 21.62.35.91.10.8-1.10.2-0.4-2.4-0.2-2.40.91.3-1.61.5-1.6-1.42.01.2-1.5-1.12.2-2.2
Locomotion velocity, session 30.40.51.20.1-0.10.1-0.4-0.0-1.00.2-1.10.80.0-0.80.9-0.9-1.01.00.6-0.90.50.6-0.6
Locomotion distance, session 30.30.30.70.50.4-0.50.2-0.4-0.8-0.3-0.80.30.6-0.50.5-0.4-0.30.70.5-0.5-0.50.9-0.9
Stereotopy head waving bouts, day 30.10.20.60.50.4-0.40.3-0.4-0.6-0.4-0.60.80.4-0.20.1-0.2-0.20.50.30.1-0.30.4-0.4
Stereotopy head waving duration, day 30.40.41.1-0.6-0.70.9-0.90.4-0.30.6-0.31.1-0.8-0.60.5-0.6-0.80.50.5-0.60.8-0.50.5
Locomotion velocity, session 72.02.26.50.90.6-0.80.0-0.4-2.50.0-2.20.71.1-1.61.8-1.5-1.42.11.0-1.9-1.32.2-2.2
Locomotion distance, session 70.50.72.50.70.6-0.90.5-0.1-0.9-0.2-0.7-0.31.1-0.70.7-0.60.10.60.1-0.4-1.61.6-1.6
Stereotopy head waving bouts, day 71.82.04.0-1.1-1.21.0-1.51.4-0.61.6-0.91.8-0.8-2.01.9-1.9-1.61.42.0-1.50.80.7-0.7
Stereotopy head waving duration, day 71.82.24.5-1.1-1.31.2-1.71.3-0.81.6-1.02.1-1.0-1.91.9-1.9-1.91.61.9-1.71.20.5-0.5
Locomotion velocity, session 81.82.24.2-1.7-1.81.6-1.92.10.02.0-0.11.4-1.4-1.71.7-1.7-1.40.92.0-1.51.20.1-0.1
Locomotion distance, session 80.71.14.0-1.3-1.31.0-1.22.00.41.60.30.8-0.8-1.41.1-1.2-0.40.31.3-0.60.70.4-0.4
Degree of sensitization distance0.60.61.80.70.8-1.00.9-0.20.2-0.50.3-1.11.00.5-0.40.40.9-0.6-1.00.8-1.30.7-0.7
Degree of sensitization stereotypy1.61.72.9-1.3-1.51.3-1.71.5-0.31.6-0.41.5-1.1-1.61.6-1.5-1.41.11.7-1.41.30.2-0.2
Conditioned locomotion0.91.02.9-0.3-0.0-0.00.40.41.5-0.21.6-0.8-0.21.1-1.21.11.3-1.7-1.31.60.5-0.90.8
Cocaine response after cond. corrected2.62.96.5-0.20.2-0.10.9-0.12.1-0.72.5-1.9-0.22.3-2.22.32.3-2.6-2.02.30.7-1.71.6
Cocaine response after cond. not corrected2.93.26.90.50.8-0.51.4-1.11.8-1.42.0-1.90.12.6-2.62.62.2-2.3-2.42.30.4-1.71.7
Cocaine response before conditioning0.30.41.40.50.20.2-0.1-1.2-1.0-0.5-1.10.9-0.2-0.20.1-0.1-1.00.9-0.0-0.70.4-0.40.4
Saline control response0.40.62.21.11.0-0.81.0-1.5-0.1-1.2-0.40.40.60.8-1.00.80.3-0.1-0.20.7-0.5-0.30.3
Bone: connectivity density1.32.03.9-1.8-1.91.9-2.01.8-0.11.90.01.5-1.7-1.41.4-1.3-1.30.71.6-1.31.3-0.50.5
Bone: cortical apparent density0.10.20.7-0.3-0.30.1-0.20.80.50.50.30.70.0-0.40.2-0.50.2-0.20.60.5-0.40.4-0.4
Bone: cortical area0.10.20.4-0.5-0.40.4-0.20.40.50.30.6-0.2-0.40.3-0.30.30.3-0.5-0.20.30.5-0.50.5
Bone: cortical porosity0.80.83.40.20.00.7-0.0-1.6-0.1-0.8-0.4-0.3-0.80.9-1.10.9-0.6-0.2-1.1-0.21.1-1.81.8
Bone: cortical porosity0.80.93.60.1-0.00.7-0.1-1.6-0.2-0.8-0.40.0-0.90.9-1.10.9-0.7-0.1-1.0-0.21.4-1.81.9
Bone: cortical thickness0.60.92.5-0.7-0.60.8-0.20.11.10.11.2-0.6-1.01.0-1.11.00.6-1.1-1.10.71.3-1.61.6
Bone: cortical thickness0.91.02.60.50.3-0.4-0.1-0.2-1.50.1-1.60.90.6-1.21.1-1.2-1.21.41.2-1.1-0.51.3-1.3
Bone: cortical tissue density0.20.20.8-0.4-0.30.1-0.20.90.40.50.30.70.0-0.50.3-0.60.1-0.20.70.5-0.40.5-0.5
Condit. Reinf. active minus inactive responses1.01.12.51.51.6-1.51.4-1.5-0.8-1.4-0.8-1.01.50.6-0.60.60.40.1-0.40.3-1.20.8-0.8
Condit. Reinf. active-inactive response ratio1.31.43.21.31.5-1.41.6-1.40.2-1.50.2-1.81.21.4-1.31.41.2-0.8-1.31.0-0.90.1-0.1
Condit. Reinf. active responses1.11.33.91.31.1-1.00.6-1.3-2.0-0.8-1.90.11.1-0.60.5-0.6-1.11.40.9-1.1-0.91.3-1.2
Condit. Reinf. inactive responses2.32.86.50.1-0.30.4-1.0-0.2-2.50.6-2.42.1-0.1-2.01.9-2.1-2.62.52.2-2.40.21.1-1.0
Incentive salience index mean1.01.22.71.61.7-1.61.5-1.5-0.9-1.4-0.9-1.01.50.6-0.50.50.30.2-0.40.1-1.10.9-0.9
Condit. Reinf. lever presses0.40.61.91.10.9-0.80.6-1.1-1.2-0.8-1.40.10.8-0.10.1-0.3-0.70.90.2-0.6-0.10.6-0.6
Condit. Reinf. active minus inactive responses0.91.13.61.41.4-1.11.3-1.9-0.9-1.6-0.6-1.51.10.8-1.00.90.40.0-0.80.1-1.20.1-0.1
Condit. Reinf. active-inactive response ratio1.71.86.11.11.3-1.21.5-1.40.5-1.50.6-2.51.01.5-1.71.51.5-1.2-1.51.2-1.4-0.30.3
Condit. Reinf. active responses1.62.26.22.22.0-1.81.6-2.5-1.9-2.0-1.7-0.61.80.3-0.50.4-0.10.9-0.2-0.2-2.11.1-1.0
Condit. Reinf. inactive responses1.51.95.11.71.4-1.30.8-1.7-2.2-1.1-2.21.11.4-0.60.6-0.6-1.01.80.6-0.9-1.41.5-1.5
Condit. Reinf. lever presses0.10.21.00.50.4-0.30.3-0.7-0.4-0.5-0.4-0.90.30.1-0.30.1-0.10.2-0.2-0.3-1.00.0-0.0
Condit. Reinf. lever reinforcers received1.42.05.12.11.9-1.71.5-2.3-1.9-1.8-1.7-0.51.80.1-0.30.1-0.21.00.0-0.3-2.11.2-1.2
Conditioned reinforcement - actives0.20.20.60.80.7-0.70.7-0.8-0.5-0.7-0.30.50.7-0.0-0.30.20.10.1-0.20.5-0.30.4-0.4
Conditioned reinforcement - inactives0.10.10.80.10.0-0.0-0.00.0-0.20.1-0.20.90.0-0.20.2-0.1-0.20.20.10.20.40.2-0.1
Conditioned locomotion1.82.25.91.00.7-0.70.0-0.7-2.4-0.2-2.41.41.0-1.61.5-1.5-1.52.21.5-1.5-0.91.9-1.9
Patch foraging indifference point 0 sec1.01.53.9-1.6-1.61.4-1.62.00.21.80.00.8-1.2-1.41.3-1.4-1.10.51.8-1.1-0.10.1-0.1
Patch foraging indifference point AUC2.42.88.0-0.6-1.11.2-1.70.3-2.01.1-2.02.8-1.0-2.02.0-2.0-2.62.21.7-2.11.20.3-0.3
Delay disc. indifference point, 0s delay0.30.31.30.70.6-0.60.4-0.6-0.6-0.4-0.80.10.7-0.20.2-0.2-0.10.60.3-0.1-1.10.7-0.7
Delay disc. indifference point, 16s delay0.80.82.0-1.4-1.31.3-1.21.31.01.20.8-0.4-1.3-0.40.2-0.3-0.3-0.30.4-0.60.4-0.90.9
Delay disc. indifference point, 2s delay0.30.40.9-1.0-0.80.8-0.70.90.90.70.7-0.7-0.8-0.1-0.1-0.1-0.0-0.40.1-0.2-0.1-0.70.7
Delay disc. indifference point, 24s delay0.70.72.1-1.4-1.21.1-1.01.51.01.21.0-0.1-1.1-0.30.1-0.2-0.1-0.60.2-0.10.6-0.80.8
Delay disc. indifference point, 4s delay0.10.10.4-0.4-0.40.5-0.50.20.00.4-0.2-0.0-0.4-0.30.3-0.3-0.50.30.4-0.60.0-0.20.2
Delay disc. indifference point, 8s delay0.50.51.7-0.6-0.40.4-0.10.51.30.31.1-1.2-0.50.5-0.60.50.5-1.0-0.60.4-0.3-0.80.8
Indifference point function ln k2.53.510.20.61.2-1.31.8-0.32.2-1.22.2-3.21.12.2-2.22.22.8-2.4-1.92.3-1.7-0.30.2
Indifference point function log k2.53.510.20.61.2-1.31.8-0.32.2-1.22.2-3.21.12.2-2.22.22.8-2.4-1.92.3-1.7-0.30.2
Patch foraging total patch changes 0 sec0.91.43.2-1.6-1.61.4-1.61.80.21.70.10.9-1.2-1.31.2-1.2-1.10.51.7-1.00.1-0.10.1
Patch foraging total patch changes 12 sec1.21.63.2-1.5-1.71.7-1.81.20.11.5-0.21.8-1.7-1.11.0-1.1-1.40.61.4-1.01.0-0.80.9
Patch foraging total patch changes 18 sec1.21.53.3-1.1-1.31.3-1.51.2-0.81.5-0.61.8-1.0-1.51.6-1.3-1.41.21.6-1.50.90.2-0.2
Patch foraging total patch changes 24 sec4.75.89.9-2.5-2.82.7-3.12.6-1.12.9-1.12.5-2.3-2.82.8-2.7-2.91.92.7-2.82.2-0.10.1
Patch foraging total patch changes 6 sec3.04.48.8-2.6-2.82.9-3.02.20.12.6-0.32.6-2.7-1.81.8-1.8-2.31.12.1-1.81.9-1.21.3
Patch foraging time to switch 0 sec0.30.51.4-0.10.1-0.30.50.31.1-0.11.2-0.90.10.8-0.70.81.2-1.0-0.70.90.1-0.30.2
Patch foraging water rate 0 sec0.30.41.0-0.9-0.91.0-0.90.70.40.80.40.7-1.0-0.20.3-0.3-0.4-0.10.5-0.20.5-0.70.8
Patch foraging water rate 12 sec0.00.00.10.20.2-0.20.2-0.20.3-0.30.10.00.10.2-0.30.30.2-0.3-0.30.3-0.1-0.10.1
Patch foraging water rate 18 sec0.10.10.30.40.3-0.40.2-0.3-0.5-0.2-0.50.20.4-0.20.2-0.3-0.20.40.3-0.1-0.40.5-0.5
Patch foraging water rate 24 sec2.02.74.8-1.6-1.81.5-2.02.0-0.72.1-0.71.9-1.2-2.12.1-2.2-1.81.42.1-1.70.70.6-0.6
Patch foraging water rate 6 sec0.00.00.1-0.1-0.10.2-0.0-0.00.3-0.00.10.2-0.20.1-0.20.20.1-0.20.20.20.1-0.30.3
Seeking ratio, delayed vs. immediate footshock0.40.51.3-0.8-0.90.9-1.00.6-0.30.9-0.20.1-0.8-0.70.7-0.5-0.80.50.8-1.10.6-0.20.3
Distance traveled before self-admin1.61.73.4-1.7-1.81.8-1.91.70.11.80.11.2-1.6-1.21.2-1.3-1.20.61.2-1.11.3-0.50.5
Distance traveled after self-admin1.11.23.1-0.7-0.90.8-1.20.9-1.01.2-1.00.6-0.6-1.41.5-1.4-1.41.31.3-1.70.50.5-0.5
Extensor digitorum longus weight0.93.58.6-0.4-0.80.7-1.50.5-2.01.1-2.31.5-0.3-2.62.4-2.6-2.82.52.6-2.9-0.11.3-1.3
Bone: elastic displacement0.80.92.0-0.20.00.10.40.01.2-0.31.3-1.4-0.31.1-1.31.21.1-1.4-1.21.00.3-1.01.0
Bone: elastic work1.31.74.40.40.7-0.61.1-0.61.5-1.01.3-1.40.31.6-2.11.71.6-1.9-1.52.00.2-1.01.0
Bone: endosteal estimation0.61.33.80.80.7-1.00.3-0.1-1.4-0.1-1.40.11.2-1.21.1-1.2-0.71.21.2-0.9-1.71.9-1.9
Bone: endosteal perimeter0.30.61.21.10.9-1.00.7-0.8-1.0-0.7-0.8-0.11.1-0.20.2-0.1-0.10.60.1-0.2-1.11.0-1.0
Epididymis fat weight0.40.92.01.31.3-1.41.1-1.2-0.9-1.0-0.8-0.51.40.1-0.20.20.20.4-0.00.1-1.31.1-1.1
Delta time in closed arm before/after self-admin0.10.10.3-0.5-0.50.6-0.50.3-0.30.40.20.1-0.4-0.40.2-0.2-0.20.10.4-0.4-0.1-0.20.2
Delta time in open arm before/after self-admin0.80.71.60.91.0-0.91.1-1.00.6-1.10.2-1.30.80.9-1.00.90.8-0.7-1.00.8-0.90.0-0.0
Diff in mean of infusions in LGA sessions0.40.41.3-0.9-0.80.7-0.81.20.51.10.0-0.4-0.7-0.30.6-0.4-0.40.30.3-0.80.7-0.10.1
Delay discount exponential model param0.80.81.91.41.2-1.21.0-1.2-1.3-1.0-1.10.81.30.00.1-0.00.00.7-0.00.2-0.41.1-1.1
Extinction: sum of active levers before priming0.10.10.50.20.2-0.20.1-0.2-0.7-0.1-0.6-0.60.3-0.10.2-0.3-0.20.30.1-0.5-0.20.5-0.5
Active lever presses in extinction session 60.30.20.9-0.3-0.30.3-0.40.4-0.40.5-0.6-0.2-0.1-0.60.7-0.7-0.70.60.6-0.90.30.4-0.3
Bone: final force0.20.41.60.50.4-0.20.0-0.6-1.1-0.2-1.30.40.4-0.70.4-0.7-1.00.80.5-0.7-0.30.5-0.5
Bone: final moment0.10.10.60.20.1-0.0-0.1-0.3-0.5-0.1-0.70.30.1-0.40.1-0.5-0.70.40.4-0.4-0.00.2-0.2
Food consumed during 24 hour testing period0.20.31.2-0.1-0.1-0.2-0.10.6-0.10.4-0.1-0.40.3-0.60.6-0.6-0.10.20.4-0.3-1.10.9-0.9
Glucose1.21.83.21.51.6-1.61.8-1.50.2-1.70.3-1.21.41.4-1.31.41.4-1.0-1.71.5-1.50.3-0.3
Heart weight0.20.30.9-0.7-0.60.8-0.60.20.00.50.30.0-0.9-0.0-0.1-0.0-0.40.00.4-0.41.0-0.90.9
Delay discount hyperbolic model param0.60.61.51.21.0-1.00.8-1.0-1.2-0.8-1.00.81.1-0.00.2-0.1-0.00.60.00.2-0.21.0-1.0
Intermittent access intake day 1-15 change1.41.45.0-0.6-0.90.8-1.20.8-1.01.1-1.02.2-0.6-1.41.4-1.4-1.51.31.3-1.11.20.5-0.4
Intermittent access intake escalation0.60.62.8-0.3-0.50.5-0.70.5-0.70.6-0.71.7-0.4-0.80.9-0.9-1.00.90.8-0.60.90.3-0.3
Intermittent access intake escalation 20.30.31.00.50.3-0.30.1-0.3-1.0-0.1-1.00.90.4-0.50.5-0.6-0.60.80.5-0.4-0.10.7-0.7
Intermitt. access day 1 inactive lever presses0.10.10.50.00.0-0.10.10.00.3-0.00.30.3-0.00.4-0.20.30.3-0.3-0.30.40.7-0.20.2
Intermitt. access day 15 inactive lever presses0.40.40.80.90.9-0.90.9-0.9-0.1-0.9-0.10.20.80.6-0.50.50.5-0.1-0.50.7-0.30.3-0.3
Intermitt. access escalation Index0.10.10.20.40.3-0.30.2-0.3-0.3-0.2-0.40.30.4-0.10.3-0.1-0.10.40.1-0.2-0.10.5-0.5
Intermittent access day 1 total infusions2.02.35.12.22.2-2.32.1-2.1-0.7-2.0-0.6-1.02.11.0-0.91.11.2-0.1-1.11.0-1.51.1-1.1
Intermittent access day 15 total infusions0.80.92.71.00.8-0.80.4-0.7-1.7-0.4-1.51.20.9-0.60.8-0.6-0.61.30.6-0.5-0.01.3-1.3
Intermittent access terminal intake (last 3 days)1.71.94.41.91.7-1.71.2-1.6-2.1-1.2-1.91.01.8-0.40.5-0.4-0.41.40.3-0.3-1.01.9-1.8
Intermittent access total infusions1.61.74.01.91.6-1.71.2-1.6-2.0-1.2-1.80.81.8-0.40.5-0.3-0.31.30.3-0.3-0.91.8-1.8
Intermittent access day 1 locomotion0.70.71.61.31.2-1.21.0-1.1-1.0-0.9-0.9-0.31.20.00.00.10.10.5-0.1-0.1-0.81.0-1.0
Intermittent access day 15 total locomotion2.52.75.3-0.6-1.00.9-1.51.0-1.91.4-1.82.3-0.6-2.12.3-2.1-2.12.22.1-2.00.91.1-1.0
Intermittent access total locomotion1.82.15.20.60.2-0.3-0.4-0.2-2.30.3-2.21.80.6-1.71.8-1.6-1.72.21.7-1.7-0.21.7-1.7
Intermittent access standard deviation0.10.10.5-0.3-0.30.3-0.30.3-0.10.30.00.4-0.3-0.40.1-0.2-0.10.00.1-0.00.7-0.20.2
Left kidney weight0.10.31.2-0.8-0.60.4-0.31.10.90.71.0-0.1-0.40.1-0.00.00.5-0.60.20.50.5-0.20.1
Right kidney weight0.30.92.2-1.1-1.10.9-1.11.50.01.3-0.10.9-0.6-1.11.2-1.2-0.80.61.5-0.80.40.4-0.4
Cocaine induced anxiety0.60.71.70.80.7-0.70.4-0.7-1.3-0.4-1.2-0.30.8-0.60.6-0.6-0.61.00.6-0.9-1.31.1-1.1
Post-drug Anxiety1.01.12.71.51.4-1.41.1-1.4-1.1-1.2-1.1-0.51.5-0.00.0-0.0-0.00.70.1-0.3-1.61.2-1.2
Baseline Anxiety0.30.41.2-0.7-0.60.6-0.40.60.90.50.80.1-0.70.3-0.30.30.3-0.7-0.30.51.1-0.80.8
Tail length0.20.72.0-0.7-0.50.4-0.10.61.30.31.4-0.5-0.60.8-0.70.80.8-1.2-0.80.90.8-0.90.9
Length with tail0.20.83.30.50.7-0.80.9-0.30.7-0.60.8-1.80.61.1-1.01.11.1-1.0-1.20.8-0.7-0.10.1
Length without tail0.71.64.01.61.7-1.91.6-1.1-0.7-1.3-0.7-2.01.90.5-0.30.40.60.1-0.60.1-2.01.5-1.5
Times rat made contact with spout0.70.84.11.01.1-1.41.0-0.4-0.1-0.7-0.4-0.41.4-0.2-0.0-0.10.6-0.0-0.10.6-2.01.4-1.4
Lifetime Intake1.61.84.22.01.9-1.91.5-1.8-1.8-1.5-1.60.41.9-0.10.1-0.0-0.01.0-0.00.0-1.21.7-1.7
Liver weight, left1.01.75.21.61.6-2.01.4-0.7-0.9-1.0-1.0-0.22.1-0.50.3-0.40.30.50.30.2-1.92.2-2.3
Liver weight, right0.10.20.70.60.6-0.60.5-0.5-0.3-0.5-0.40.80.6-0.1-0.00.00.00.20.20.4-0.10.5-0.5
Locomotor activity1.62.57.82.12.2-1.72.1-2.8-0.2-2.5-0.3-1.01.41.9-1.91.91.1-0.6-1.51.2-0.8-0.50.5
Locomotor testing distance0.71.15.31.71.5-1.01.1-2.3-1.3-1.6-1.5-0.10.90.5-0.60.5-0.30.8-0.3-0.3-0.70.00.0
Locomotor testing rearing0.10.20.90.60.5-0.20.4-0.9-0.4-0.7-0.50.50.10.3-0.50.4-0.10.3-0.10.10.3-0.50.5
Locomotion in novel chamber0.70.82.80.80.6-0.60.2-0.6-1.7-0.3-1.40.20.8-0.80.7-0.7-0.61.21.0-1.0-0.91.1-1.1
Locomotion in novel chamber post-restriction0.10.20.5-0.4-0.40.5-0.30.10.50.20.4-0.1-0.50.4-0.30.30.1-0.4-0.10.30.1-0.70.7
Fecal boli incidents, locomotor time 11.61.83.61.11.3-1.41.6-0.90.9-1.31.1-1.41.11.8-1.51.81.9-1.3-1.41.8-0.9-0.00.0
Change in fecal boli incidents, locomotor task1.21.12.3-0.6-0.90.8-1.10.6-1.00.9-0.91.5-0.6-1.41.3-1.4-1.51.21.4-1.30.20.3-0.3
Time >=10cm from walls, locomotor time 10.10.10.20.20.2-0.20.3-0.20.0-0.20.2-0.30.20.2-0.10.30.2-0.3-0.50.3-0.5-0.00.0
Bouts of movement, locomotor time 10.40.40.90.20.3-0.20.5-0.50.7-0.50.7-0.40.11.0-0.80.80.8-0.8-0.80.90.5-0.50.5
Total resting periods, locomotor time 11.01.12.30.20.4-0.30.8-0.51.4-0.71.3-1.00.11.5-1.31.41.4-1.4-1.31.40.3-0.90.9
Rest time, locomotor task time 10.91.03.31.11.2-1.21.3-1.00.2-1.20.2-1.31.10.9-0.90.90.9-0.5-0.80.8-1.80.3-0.3
Distance moved, locomotor task time 11.51.63.0-0.9-1.11.0-1.41.0-1.11.3-1.21.4-0.8-1.61.6-1.6-1.61.41.4-1.71.40.5-0.5
Vertical activity count, locomotor time 11.21.32.0-1.2-1.31.2-1.41.3-0.41.4-0.41.3-1.0-1.41.3-1.3-1.30.81.1-1.21.40.1-0.1
Time >=10cm from walls, locomotor time 20.10.10.40.30.3-0.30.4-0.40.0-0.40.1-0.60.30.2-0.30.10.2-0.3-0.20.3-0.6-0.00.0
Bouts of movement, locomotor time 21.21.33.1-0.6-0.40.6-0.00.21.8-0.01.7-0.0-0.91.3-1.11.31.0-1.5-1.11.31.4-1.61.6
Total resting periods, locomotor time 21.21.33.1-0.4-0.20.30.2-0.11.8-0.31.7-0.2-0.61.5-1.31.51.2-1.6-1.31.41.0-1.61.6
Rest time, locomotor task time 20.20.20.5-0.1-0.00.00.1-0.00.6-0.10.7-0.3-0.10.5-0.50.70.3-0.4-0.50.4-0.6-0.50.5
Distance moved, locomotor task time 20.81.03.10.40.2-0.2-0.2-0.3-1.70.1-1.80.30.4-1.11.1-1.1-1.11.41.0-1.40.21.1-1.0
Vertical activity count, locomotor time 20.91.03.01.10.9-0.80.5-0.8-1.7-0.6-1.70.21.1-0.80.7-0.8-0.71.20.6-0.8-0.81.3-1.3
Light reinforcement 10.50.82.00.50.7-0.50.9-0.91.0-1.00.7-0.70.21.3-1.41.41.0-1.0-0.81.0-0.4-0.90.9
Light reinforcement 20.10.20.60.10.3-0.30.4-0.10.8-0.40.5-0.40.30.5-0.70.40.6-0.6-0.10.70.0-0.10.1
Bone: marrow area0.61.33.90.70.6-0.90.20.1-1.40.1-1.30.11.1-1.41.2-1.3-0.71.21.3-1.0-1.62.0-2.0
Bone: maximum diameter0.00.10.2-0.3-0.30.3-0.20.40.10.40.20.4-0.2-0.10.0-0.10.0-0.10.30.10.2-0.10.1
Bone: maximum force0.10.20.40.50.5-0.50.5-0.5-0.0-0.5-0.1-0.30.50.3-0.60.30.3-0.2-0.10.4-0.60.1-0.1
Bone: maximum moment0.10.20.70.30.4-0.40.5-0.30.4-0.50.4-0.50.30.6-0.90.60.6-0.6-0.20.7-0.5-0.30.2
Mean time between licks in bursts2.02.86.20.71.0-1.01.6-0.71.8-1.31.9-2.20.72.2-2.12.22.5-2.2-2.12.2-1.0-0.80.7
Mean num. licks in bursts1.82.23.91.61.8-1.72.0-1.70.7-1.90.3-1.31.41.6-1.81.61.5-1.2-1.71.9-1.1-0.0-0.0
Cd content in liver0.70.82.51.41.4-1.21.3-1.6-0.5-1.4-0.40.21.00.8-0.80.80.50.1-0.40.6-0.60.2-0.2
Co content in liver0.30.30.90.80.7-0.70.5-0.7-0.9-0.5-0.70.00.70.00.2-0.1-0.20.70.5-0.5-0.40.7-0.7
Cu content in liver0.40.41.00.40.6-0.70.8-0.20.7-0.50.6-1.00.60.8-0.70.71.0-0.7-0.60.8-0.50.1-0.1
Fe content in liver1.31.63.51.01.1-0.91.3-1.50.6-1.50.6-1.60.61.8-1.71.81.2-1.1-1.91.2-0.3-0.80.8
K content in liver0.70.71.5-1.2-1.11.1-0.91.11.10.91.10.2-1.10.0-0.10.10.3-0.70.20.30.9-1.00.9
Mg content in liver1.31.33.8-1.1-0.70.7-0.30.91.90.51.8-1.1-0.90.9-1.01.01.2-1.7-0.91.20.7-1.41.3
Mn content in liver1.11.23.5-0.8-0.50.6-0.00.71.60.31.9-0.6-0.81.2-1.11.41.4-1.5-0.91.30.8-1.31.3
Na content in liver1.01.12.5-1.1-1.21.2-1.41.20.11.3-0.41.6-1.0-1.31.1-1.3-1.20.71.4-0.80.5-0.10.1
Rb content in liver0.40.51.7-0.3-0.30.6-0.1-0.40.5-0.20.7-0.6-0.71.0-0.70.90.4-0.5-0.60.11.2-1.31.3
Se content in liver0.60.72.71.41.3-1.11.1-1.7-0.9-1.3-0.90.31.00.3-0.40.4-0.10.5-0.30.2-0.60.4-0.4
Sr content in liver1.00.91.80.1-0.20.2-0.50.0-1.20.4-1.31.20.0-1.31.2-1.3-1.31.31.2-1.2-0.00.8-0.8
Zn content in liver0.70.82.4-0.6-0.30.10.10.91.50.31.4-1.5-0.20.7-0.80.71.2-1.4-0.71.0-0.1-0.60.5
Bone: minimum diameter0.30.61.80.60.7-0.81.0-0.40.4-0.60.7-1.40.70.9-0.81.01.2-0.8-0.80.8-0.80.1-0.1
Time in familiar zone, hab. session 10.30.32.00.70.6-0.70.6-0.5-0.4-0.5-0.3-0.20.8-0.1-0.0-0.00.20.20.20.3-1.40.7-0.7
Time in novel zone, hab. session 11.81.74.9-1.7-1.82.0-1.71.10.41.40.41.3-2.0-0.50.5-0.5-1.00.10.5-0.82.2-1.51.5
Total zone transitions, hab. session 10.71.02.9-0.7-0.91.0-1.20.4-1.10.8-1.00.6-0.9-1.11.0-1.0-1.51.21.1-1.70.8-0.20.2
Total locomotion distance, hab. session 12.13.05.7-1.7-2.02.2-2.31.1-0.91.8-1.01.7-2.0-1.61.7-1.7-2.41.61.6-2.41.7-0.80.8
Locomotion velocity, hab. session 12.02.86.1-1.5-1.92.1-2.21.0-1.01.7-1.11.5-1.9-1.61.7-1.7-2.41.71.5-2.51.7-0.60.7
Time in familiar zone, hab. session 21.01.02.60.20.3-0.00.6-0.80.9-0.80.9-0.4-0.31.6-1.51.40.9-1.0-1.41.20.9-1.41.4
Time in novel zone, hab. session 21.51.53.2-1.1-1.21.0-1.41.5-0.51.5-0.60.8-0.7-1.81.7-1.6-1.31.01.7-1.60.10.6-0.6
Total zone transitions, hab. session 20.50.61.80.30.1-0.0-0.3-0.3-1.30.1-1.30.80.1-0.90.8-0.8-1.11.20.8-1.10.40.6-0.6
Total locomotion distance, hab. session 20.40.51.40.0-0.20.4-0.5-0.4-1.10.2-1.10.8-0.3-0.80.7-0.7-1.21.10.8-1.20.30.1-0.0
Locomotion velocity, hab. session 20.50.72.10.3-0.00.2-0.4-0.5-1.40.1-1.51.0-0.0-0.90.9-0.9-1.31.40.9-1.30.00.4-0.4
Novel to familiar place preference ratio3.94.09.1-3.0-2.93.0-2.62.51.82.41.50.8-3.0-0.70.5-0.6-0.7-0.60.9-0.62.6-2.22.2
Novelty place preference5.05.111.8-3.4-3.33.4-3.02.81.82.81.51.1-3.4-0.90.7-0.9-1.0-0.51.1-0.83.0-2.42.4
Time in novel zone, NPP test5.55.713.0-3.6-3.53.6-3.13.01.93.01.61.1-3.5-1.00.8-0.9-1.0-0.51.2-0.83.1-2.52.5
Total zone transitions, NPP test1.31.95.61.51.1-1.10.6-1.3-2.3-0.8-2.40.81.3-1.01.0-1.0-1.21.90.6-1.3-1.11.7-1.7
Total locomotion distance, NPP test0.71.03.11.00.7-0.60.3-1.2-1.8-0.6-1.80.80.7-0.70.7-0.7-1.11.40.5-1.0-0.81.0-0.9
Locomotion velocity, NPP test0.91.34.21.41.0-0.80.5-1.6-2.1-0.9-2.00.71.0-0.60.6-0.6-1.11.50.3-1.0-1.01.1-1.0
Intraocular pressure0.81.12.21.21.3-1.21.4-1.20.5-1.30.1-1.51.11.1-1.21.00.9-0.7-1.00.9-1.20.1-0.1
Delta distance traveled before/after self-admin0.70.81.71.31.3-1.31.1-1.2-0.7-1.0-0.9-0.51.30.1-0.10.20.20.5-0.2-0.1-1.11.0-1.0
Delta ambulatory time before/after self-admin0.50.61.21.11.0-1.00.8-0.9-0.8-0.8-1.0-0.31.1-0.10.2-0.1-0.10.70.1-0.3-0.81.0-1.0
Parametrial fat weight0.61.23.70.40.3-0.70.00.3-1.10.3-1.00.70.9-1.31.3-1.2-0.71.21.4-0.8-1.31.9-1.9
Pavlov. Cond. lever latency0.70.92.3-1.3-1.21.3-1.00.81.00.81.00.4-1.40.0-0.20.20.1-0.6-0.20.21.5-1.31.3
Pavlov. Cond. magazine entry latency0.30.41.0-0.3-0.30.0-0.40.8-0.40.7-0.4-0.50.1-0.81.0-0.9-0.60.50.5-0.8-0.50.9-0.9
Pavlov. Cond. change in total contacts0.20.20.70.60.6-0.70.6-0.4-0.2-0.4-0.2-0.10.60.2-0.10.10.10.10.20.2-0.80.5-0.5
Pavlov. Cond. index score1.11.43.70.70.5-0.80.10.0-1.50.1-1.50.31.0-1.21.4-1.4-1.01.41.1-1.2-1.21.9-1.9
Pavlov. Cond. latency score0.91.23.41.00.8-1.10.5-0.3-1.4-0.2-1.40.11.2-0.91.1-1.0-0.71.20.8-0.9-1.31.9-1.8
Pavlov. Cond. lever contacts1.01.23.21.31.2-1.40.8-0.6-1.3-0.6-1.3-0.11.5-0.50.6-0.7-0.31.00.6-0.5-1.61.8-1.8
Pavlov. Cond. magazine entry number1.31.63.90.40.5-0.00.8-1.40.9-1.31.0-0.5-0.21.8-2.02.01.2-1.3-1.61.50.5-1.81.8
Pavlov. Cond. intertrial magazine entries0.91.12.80.60.8-0.51.0-1.10.9-1.10.7-1.20.31.3-1.71.41.1-1.2-1.41.4-0.1-0.80.8
Pavlov. Cond. lever-magazine prob. diff.1.01.33.30.50.3-0.6-0.10.2-1.50.2-1.50.30.9-1.31.5-1.5-1.11.41.1-1.3-1.11.8-1.8
Pavlov. Cond. response bias1.31.63.8-0.2-0.3-0.1-0.61.1-1.21.0-1.20.40.4-1.81.9-2.0-1.21.41.7-1.5-0.81.8-1.8
Pavlov. Cond. lever latency0.40.51.60.20.4-0.60.70.21.1-0.31.0-0.60.40.8-0.70.91.3-1.0-0.81.2-0.20.0-0.1
Pavlov. Cond. magazine entry latency0.20.31.0-0.5-0.30.1-0.10.90.90.41.0-0.7-0.10.1-0.20.10.8-0.70.10.5-0.20.1-0.1
Pavlov. Cond. change in total contacts0.50.72.21.11.0-0.80.6-1.5-1.5-0.9-1.3-0.60.8-0.10.1-0.1-0.60.8-0.1-0.8-0.80.6-0.6
Pavlov. Cond. index score0.20.30.7-0.2-0.20.2-0.40.2-0.70.3-0.5-0.0-0.0-0.70.6-0.7-0.60.60.8-0.8-0.20.5-0.5
Pavlov. Cond. latency score0.20.20.6-0.1-0.10.0-0.30.2-0.80.3-0.5-0.20.1-0.70.6-0.7-0.50.50.7-0.8-0.30.6-0.6
Pavlov. Cond. lever contacts0.50.71.8-0.7-0.91.0-1.10.4-0.90.8-0.80.7-0.8-1.00.9-1.0-1.30.90.7-1.30.6-0.20.2
Pavlov. Cond. magazine entry number0.40.51.10.70.6-0.40.7-1.00.3-0.90.20.10.21.0-1.01.00.5-0.5-1.00.80.1-0.70.7
Pavlov. Cond. intertrial magazine entries0.60.82.80.60.4-0.3-0.1-0.7-1.4-0.1-1.71.20.4-0.90.9-0.9-1.21.40.9-1.1-0.40.8-0.7
Pavlov. Cond. lever-magazine prob. diff.0.20.30.7-0.0-0.10.0-0.30.1-0.80.2-0.70.00.1-0.80.7-0.8-0.70.70.8-0.9-0.40.6-0.6
Pavlov. Cond. response bias0.30.41.1-0.6-0.80.8-0.90.3-0.60.7-0.50.3-0.7-0.70.7-0.7-1.00.60.5-1.10.4-0.30.3
Time in closed arm before self-admin0.20.21.5-0.5-0.40.3-0.40.70.50.60.20.5-0.40.10.20.0-0.0-0.1-0.1-0.01.2-0.20.2
Time in closed arm after self-admin0.10.10.4-0.4-0.30.3-0.10.40.50.30.6-0.1-0.30.3-0.20.40.4-0.4-0.30.20.6-0.40.4
Time in open arm before self-admin0.60.71.2-0.9-1.01.0-1.10.8-0.50.9-0.30.6-0.8-1.00.7-1.1-1.00.51.1-0.90.3-0.20.2
Time in open arm after self-admin0.10.10.70.10.2-0.10.2-0.30.2-0.3-0.0-0.80.20.2-0.30.10.0-0.3-0.20.1-0.6-0.10.1
Bone: periosteal estimation0.20.31.10.30.3-0.50.10.2-0.70.1-0.6-0.10.6-0.70.5-0.7-0.30.40.7-0.4-0.81.0-1.1
Bone: periosteal perimeter0.20.30.70.40.4-0.20.5-0.80.1-0.60.2-0.20.10.8-0.80.80.4-0.5-0.80.60.2-0.60.6
Bone: post-yield work1.01.34.11.21.4-1.61.5-0.70.2-1.10.3-1.71.50.8-0.70.81.3-0.6-0.80.9-2.00.9-1.0
Progressive ratio test 1 active lever presses1.21.23.61.41.1-1.20.7-1.0-1.9-0.7-1.70.81.3-0.70.7-0.6-0.51.40.5-0.7-0.31.6-1.6
Progressive ratio test 1 breakpoint1.41.54.21.41.2-1.30.7-1.1-2.1-0.8-1.90.91.4-0.80.9-0.7-0.61.50.6-0.8-0.51.8-1.7
Progressive ratio test 1 inactive lever presses0.60.71.71.31.2-1.21.0-1.1-1.0-1.0-0.80.61.20.1-0.00.20.10.50.00.3-0.61.0-1.0
Progressive ratio test 2 active lever presses1.51.65.21.31.0-1.00.5-1.0-2.3-0.5-2.01.31.2-1.21.0-1.0-1.01.71.0-0.9-0.71.7-1.7
Progressive ratio test 2 breakpoint1.92.16.61.00.7-0.70.1-0.7-2.6-0.2-2.31.81.0-1.61.4-1.4-1.52.11.4-1.3-0.51.9-1.8
Progressive ratio test 2 inactive lever presses0.50.61.61.00.8-0.90.6-0.8-1.3-0.6-1.00.90.9-0.40.3-0.2-0.30.80.3-0.0-0.61.0-1.0
Incentive Sensitization - Responses1.91.94.60.50.1-0.2-0.4-0.2-2.20.3-2.11.70.5-1.81.6-1.6-1.72.11.6-1.5-0.61.5-1.5
Incentive Sensitization - Breakpoint1.81.94.80.60.3-0.3-0.3-0.3-2.20.1-2.11.60.6-1.71.5-1.5-1.62.11.5-1.4-0.71.6-1.6
Sum of active levers in priming session hrs 5-61.61.53.11.71.6-1.71.3-1.5-1.3-1.2-1.5-0.71.7-0.00.2-0.1-0.01.00.0-0.4-1.81.6-1.6
Progressive ratio0.10.10.40.50.4-0.30.3-0.6-0.5-0.5-0.3-0.10.3-0.0-0.10.2-0.20.2-0.1-0.0-0.30.1-0.1
Food seeking constrained by brief footshock0.30.41.8-0.5-0.40.4-0.20.40.90.20.9-1.4-0.50.5-0.30.50.4-0.6-0.70.1-0.2-0.70.7
Seeking ratio, punishment vs. effort0.30.41.1-1.0-0.90.8-0.71.01.00.80.7-0.5-0.80.10.1-0.00.2-0.4-0.1-0.10.4-0.60.6
Retroperitoneal fat weight0.30.92.61.00.9-1.10.6-0.6-1.4-0.5-1.20.21.2-0.60.7-0.6-0.41.00.5-0.5-1.31.6-1.6
Reaction time number correct1.92.86.32.52.2-2.11.7-2.4-2.3-1.8-2.20.52.2-0.10.2-0.0-0.51.5-0.2-0.3-1.81.8-1.8
Reaction time mean minus median0.60.85.4-0.20.2-0.10.40.21.0-0.21.2-2.30.01.0-0.90.91.1-1.1-1.00.5-0.5-0.50.5
Reaction time mean minus median AUC0.30.31.9-0.6-0.30.4-0.20.60.90.30.8-1.4-0.40.4-0.40.40.4-0.7-0.40.10.0-0.50.5
Reaction time num false alarms0.20.30.90.0-0.10.5-0.4-0.6-0.8-0.1-0.90.4-0.4-0.40.1-0.4-1.00.80.2-0.80.3-0.40.5
Reaction time num false alarms AUC0.30.41.50.2-0.00.3-0.4-0.6-1.1-0.1-1.20.7-0.2-0.70.5-0.7-1.11.00.3-1.0-0.00.00.0
Reaction time trials correct on left1.92.86.32.52.2-2.11.7-2.4-2.3-1.8-2.20.52.2-0.10.2-0.0-0.51.5-0.2-0.3-1.81.8-1.8
Reaction time trials on left1.92.86.42.52.3-2.21.7-2.4-2.2-1.9-2.10.32.20.00.10.1-0.31.4-0.3-0.2-1.81.8-1.7
Reaction time mean1.92.79.81.41.7-1.51.9-1.70.7-1.90.8-3.11.22.0-2.01.91.8-1.4-2.21.3-0.9-0.40.4
Reaction time mean AUC1.92.69.41.21.5-1.21.8-1.70.8-1.80.9-3.11.02.1-2.12.01.8-1.5-2.21.2-0.6-0.70.7
Median of all reaction times1.82.57.71.51.7-1.41.9-1.90.5-2.00.6-2.81.21.9-2.01.91.6-1.2-2.21.2-0.6-0.40.4
Reaction time omissions2.93.916.00.50.9-0.81.5-1.01.9-1.32.2-4.00.42.6-2.62.52.6-2.5-2.61.8-0.5-1.41.4
Reaction time false alarm rate0.60.82.3-1.1-1.21.5-1.30.60.10.9-0.00.5-1.4-0.60.3-0.6-0.90.30.4-0.81.2-1.11.1
Reaction time premature initiation rate1.31.74.4-1.3-1.11.3-0.70.81.90.61.80.5-1.51.0-1.10.80.7-1.5-0.51.31.8-2.12.1
Reaction time premature initiations0.30.41.10.30.3-0.10.4-0.60.4-0.60.30.7-0.10.8-0.90.70.4-0.6-0.61.00.5-0.80.8
Std. dev. reaction times0.60.97.00.10.4-0.40.7-0.10.8-0.51.0-2.60.31.1-1.01.01.2-1.1-1.10.4-0.4-0.40.3
Reaction time trials completed1.92.86.42.52.3-2.21.7-2.4-2.2-1.9-2.10.32.20.00.10.1-0.31.4-0.3-0.2-1.81.8-1.7
Reaction time trials AUC1.82.66.22.52.2-2.11.7-2.4-2.1-1.9-2.10.32.10.10.00.1-0.31.3-0.3-0.1-1.71.6-1.6
Run reversals in cocaine runway, females0.50.51.40.1-0.1-0.1-0.30.2-1.20.4-0.91.10.1-0.80.9-0.8-0.81.00.7-0.80.80.8-0.8
Run reversals in cocaine runway, males0.40.41.80.70.6-0.70.4-0.6-0.8-0.4-0.90.10.7-0.30.4-0.3-0.40.70.6-0.4-1.30.8-0.8
Latency to leave start box in cocaine runway0.40.40.90.20.4-0.50.6-0.10.9-0.40.8-0.60.20.9-0.80.81.0-0.9-0.70.80.3-0.30.3
Latency to leave start box in cocaine runway, F0.30.40.80.20.4-0.40.6-0.20.8-0.40.7-0.30.30.9-0.70.80.9-0.8-0.70.90.4-0.30.3
Latency to leave start box in cocaine runway, M0.30.30.7-0.2-0.00.00.20.20.8-0.10.9-0.6-0.20.5-0.70.60.7-0.9-0.60.60.5-0.60.6
Std. dev. time between licks in bursts0.60.72.00.20.4-0.20.6-0.40.8-0.61.0-1.40.11.2-1.11.21.2-1.1-1.20.80.2-0.60.6
Total sessions with >9 infusions1.01.12.01.31.3-1.31.4-1.3-0.1-1.40.3-1.11.21.1-1.01.11.0-0.6-1.01.0-0.80.3-0.3
Short access day 1 total inactive lever presses2.42.75.9-0.6-0.90.8-1.40.9-1.91.3-1.82.4-0.5-2.12.2-2.1-2.12.22.1-1.90.71.1-1.0
Short access day 10 total inactive lever presses1.21.32.9-1.7-1.71.6-1.61.70.61.60.51.0-1.6-0.60.6-0.7-0.70.00.7-0.51.5-0.80.9
Short access day 1 total infusions0.60.62.01.00.8-0.80.5-0.8-1.4-0.6-1.10.50.9-0.40.4-0.4-0.40.90.5-0.3-0.81.0-1.0
Short access day 10 total infusions1.01.12.61.61.6-1.61.4-1.5-0.9-1.4-0.7-0.41.50.3-0.50.50.50.2-0.50.5-0.91.0-1.0
Short access total infusions1.31.53.61.91.8-1.81.6-1.8-1.2-1.6-0.9-0.21.80.4-0.40.50.50.3-0.40.6-1.31.2-1.2
Short access day 1 locomotion1.11.22.4-0.6-0.80.8-1.10.7-1.31.0-1.11.2-0.5-1.51.5-1.4-1.51.41.6-1.40.10.6-0.6
Short access day 10 total locomotion0.30.30.6-0.7-0.70.7-0.80.7-0.30.7-0.10.0-0.6-0.80.6-0.6-0.60.40.6-0.80.4-0.10.1
Short access total locomotion0.40.41.01.00.9-0.90.7-0.9-0.9-0.7-0.7-0.00.9-0.10.0-0.0-0.10.50.1-0.0-0.90.8-0.8
One hour access (0.3 mA shock)0.81.03.21.10.9-0.90.5-0.8-1.8-0.5-1.60.91.0-0.80.7-0.7-0.71.30.6-0.6-0.31.4-1.4
Compulsive drug intake0.40.40.90.80.7-0.70.4-0.7-0.9-0.5-0.9-0.20.8-0.20.4-0.3-0.50.80.4-0.6-1.00.9-0.9
One hour access (shock baseline)0.50.61.51.21.1-1.20.9-1.0-1.0-0.9-0.90.51.1-0.0-0.10.10.20.5-0.20.3-0.50.9-0.9
Social response proportion2.22.44.21.41.7-1.62.0-1.31.0-1.81.0-1.81.42.0-1.81.92.0-1.4-1.71.8-1.30.0-0.1
Social responses0.10.10.2-0.3-0.30.4-0.30.30.30.30.10.5-0.4-0.10.1-0.0-0.10.10.5-0.10.4-0.30.3
Social time5.06.612.81.82.2-1.82.8-2.32.3-2.82.1-2.71.33.5-3.63.63.3-2.8-3.13.3-0.9-1.41.4
Soleus weight5.616.337.7-6.1-6.06.1-5.65.52.35.42.32.4-5.8-2.22.2-2.0-2.0-0.12.7-2.14.7-3.43.4
Bone: stiffness0.10.20.40.20.2-0.20.3-0.30.3-0.30.4-0.30.10.6-0.60.60.5-0.5-0.60.6-0.4-0.30.3
Tibialis anterior weight1.86.213.5-0.8-1.21.1-2.11.0-2.61.7-2.82.4-0.5-3.53.3-3.4-3.53.33.7-3.70.11.8-1.7
Time to tail flick, vehicle, before self-admin1.51.53.00.70.9-0.91.3-0.81.1-1.11.1-1.40.61.7-1.71.61.6-1.5-1.71.7-0.3-0.60.6
Time to tail flick, vehicle, after self-admin1.41.52.71.41.5-1.41.6-1.50.4-1.60.2-1.41.31.3-1.31.21.3-0.9-1.21.3-1.60.2-0.2
Time to tail flick, test, before self-admin1.71.73.5-1.8-1.51.5-1.11.51.91.21.7-1.2-1.60.5-0.50.50.3-1.3-0.70.31.2-1.71.7
Time to tail flick, test, after self-admin1.81.94.5-2.1-1.91.9-1.62.01.51.71.3-0.3-1.90.00.1-0.2-0.2-0.8-0.0-0.21.7-1.51.5
Delta time to tail flick, vehicle, before/after SA0.70.71.41.01.1-1.01.2-1.10.2-1.10.1-0.80.90.9-0.90.80.9-0.5-0.80.9-1.10.2-0.2
Delta time to tail flick, test, before/after SA0.70.61.2-1.0-1.11.1-1.11.10.21.10.11.1-1.0-0.50.6-0.7-0.60.20.7-0.40.9-0.40.4
Tibia length1.85.213.13.33.4-3.63.2-2.4-1.1-2.8-1.0-1.13.51.0-1.01.01.4-0.2-1.41.5-2.92.4-2.4
Ambulatory time before self-admin1.31.42.7-1.5-1.61.5-1.61.5-0.01.60.11.4-1.4-1.01.0-1.1-1.00.51.0-0.91.4-0.50.5
Ambulatory time after self-admin0.70.81.7-0.6-0.70.7-1.00.8-0.71.0-0.80.8-0.5-1.11.2-1.2-1.11.11.1-1.30.50.4-0.4
Bone: tissue strength3.83.78.10.00.4-0.11.1-0.82.6-1.22.3-1.8-0.42.6-2.92.62.1-2.6-2.32.50.5-2.32.3
Total heroin consumption4.35.19.1-2.5-2.82.6-3.02.7-0.83.0-0.72.3-2.3-2.32.6-2.4-2.41.72.3-2.52.3-0.10.2
Bone: trabecular number3.75.811.6-3.1-3.33.4-3.42.7-0.03.10.02.9-3.1-2.12.1-2.1-2.31.22.5-2.12.3-1.31.3
Bone: trabecular spacing2.02.65.52.02.2-2.32.2-1.5-0.3-1.9-0.0-1.92.21.2-1.01.11.5-0.7-1.81.3-1.81.3-1.3
Bone: trabecular thickness0.50.63.4-1.1-0.90.6-0.71.80.91.20.90.2-0.5-0.60.6-0.50.4-0.50.40.20.00.3-0.3
Bone: trabecular tissue density1.92.65.70.60.9-0.91.5-0.71.8-1.31.8-1.60.52.2-2.12.22.3-2.2-2.22.4-0.4-0.90.9
Water consumed over 24 hours0.81.02.4-0.0-0.1-0.2-0.40.8-0.90.7-0.90.40.5-1.41.5-1.4-0.81.01.1-1.0-1.31.6-1.6
Number of responses in last shaping day1.11.23.2-0.8-1.01.0-1.20.9-0.91.1-0.91.8-0.7-1.21.3-1.4-1.51.21.4-1.00.70.3-0.3