Hub : Genes

Cbfb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Cbfb 0.26 0.21 3.0e-05 0.05 0.04 0.04 0.05 2.1e-05 1.0e-04 6.1e-05 3.1e-05
2 OFC gene expression Cbfb 0.42 0.27 6.9e-07 0.21 0.25 0.21 0.26 9.1e-06 1.0e-06 1.0e-05 9.1e-07
3 RMTg gene expression Cbfb 0.16 0.11 1.3e-04 0.17 0.16 0.12 0.19 2.3e-05 5.5e-05 5.4e-04 1.0e-05
4 BLA gene expression Cbfb 0.15 0.09 2.1e-08 0.12 0.15 0.14 0.13 8.8e-07 1.8e-08 5.5e-08 2.7e-07
5 IL gene expression Cbfb 0.23 0.2 1.4e-03 0.06 0.08 0.06 0.07 1.3e-02 5.0e-03 1.7e-02 1.0e-02
6 PL gene expression Cbfb 0.44 0.1 0.0e+00 0.19 0.22 0.2 0.2 1.2e-20 1.4e-23 5.8e-22 5.0e-21
7 Liver gene expression Cbfb 0.1 0.06 1.2e-13 0.1 0.1 0.1 0.09 1.1e-10 9.7e-11 1.0e-10 1.2e-10
8 NAcc gene expression Cbfb 0.03 0.03 5.0e-05 0.02 0.03 0.02 0.03 1.3e-04 3.4e-05 2.1e-04 5.6e-05
9 IC gene expression Cbfb 0.28 0.12 2.9e-12 0.25 0.23 0.21 0.23 8.8e-11 5.0e-10 3.7e-09 5.5e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.00.10.2-0.5-0.2-0.3-0.2-0.1-0.10.00.10.3
Area under the delay curve0.20.20.9-0.00.00.1-0.1-0.30.4-0.5-0.6-0.9
BMI with tail0.00.00.1-0.3-0.20.2-0.3-0.2-0.3-0.1-0.0-0.0
BMI without tail0.00.10.20.2-0.20.1-0.1-0.1-0.5-0.2-0.2-0.3
Body weight0.31.41.6-1.2-1.21.3-1.2-1.2-1.2-1.2-1.2-1.0
Weight adjusted by age0.10.10.8-0.0-0.1-0.9-0.1-0.1-0.60.00.10.2
Bone surface1.01.83.0-1.7-1.31.1-1.4-1.4-1.1-1.3-1.3-1.0
Bone volume0.71.32.5-1.6-1.20.8-1.3-1.2-1.1-1.1-1.1-0.7
Breakpoint value in progressive ratio session2.63.15.21.51.7-2.31.71.81.61.81.91.5
Number of licking bursts0.40.61.1-1.0-0.80.7-0.9-0.9-0.8-0.8-0.7-0.5
Context. condit. distance diff. score0.10.10.40.00.30.10.20.10.70.00.0-0.3
Locomotion velocity, session 10.20.20.7-0.3-0.20.4-0.3-0.40.0-0.5-0.6-0.8
Locomotion distance, session 10.00.00.10.30.2-0.20.20.2-0.10.20.20.0
Locomotion velocity, session 20.40.40.80.90.6-0.60.70.70.40.60.60.5
Locomotion distance, session 20.00.00.20.40.2-0.20.20.20.10.10.1-0.1
Locomotion velocity, session 30.30.30.40.50.7-0.60.60.60.70.60.60.5
Locomotion distance, session 30.00.00.10.20.3-0.00.10.00.1-0.0-0.0-0.3
Stereotopy head waving bouts, day 30.10.10.2-0.2-0.40.5-0.4-0.4-0.3-0.4-0.5-0.3
Stereotopy head waving duration, day 30.40.50.6-0.7-0.80.8-0.7-0.7-0.6-0.7-0.7-0.5
Locomotion velocity, session 70.10.10.3-0.10.2-0.50.20.30.20.40.40.5
Locomotion distance, session 70.10.10.30.20.4-0.20.30.20.50.10.10.0
Stereotopy head waving bouts, day 70.00.00.2-0.4-0.2-0.1-0.2-0.1-0.20.10.20.3
Stereotopy head waving duration, day 70.20.20.6-0.8-0.50.3-0.6-0.5-0.5-0.3-0.2-0.1
Locomotion velocity, session 80.30.30.7-0.10.4-0.80.40.40.40.60.70.8
Locomotion distance, session 80.30.41.20.60.8-0.40.70.51.10.40.4-0.0
Degree of sensitization distance0.00.00.1-0.1-0.00.2-0.0-0.10.3-0.2-0.2-0.1
Degree of sensitization stereotypy0.10.10.3-0.6-0.40.1-0.4-0.3-0.4-0.1-0.0-0.0
Conditioned locomotion2.02.33.2-1.5-1.31.8-1.6-1.6-1.2-1.6-1.6-1.4
Cocaine response after cond. corrected0.20.20.5-0.6-0.70.2-0.5-0.4-0.7-0.3-0.20.1
Cocaine response after cond. not corrected0.10.10.2-0.1-0.3-0.2-0.00.1-0.30.20.30.5
Cocaine response before conditioning0.91.11.71.31.0-0.91.11.11.01.01.00.6
Saline control response4.66.16.8-2.4-2.32.5-2.6-2.5-2.4-2.5-2.5-2.4
Bone: connectivity density0.10.20.50.10.4-0.70.30.40.50.50.50.6
Bone: cortical apparent density1.31.82.31.01.4-1.31.31.31.31.41.51.5
Bone: cortical area0.20.40.8-0.9-0.70.5-0.7-0.6-0.6-0.5-0.5-0.2
Bone: cortical porosity0.10.10.20.50.50.00.30.30.30.30.30.2
Bone: cortical porosity0.10.10.20.40.4-0.00.30.30.30.20.30.2
Bone: cortical thickness0.10.10.4-0.6-0.3-0.1-0.2-0.1-0.30.10.10.4
Bone: cortical thickness0.00.00.2-0.1-0.10.5-0.2-0.1-0.2-0.1-0.1-0.3
Bone: cortical tissue density1.41.92.31.01.4-1.31.31.41.31.41.51.5
Condit. Reinf. active minus inactive responses3.94.35.52.12.3-2.02.22.12.12.12.01.7
Condit. Reinf. active-inactive response ratio3.63.85.32.02.3-1.82.02.02.11.91.91.5
Condit. Reinf. active responses2.42.93.81.91.9-1.51.81.81.81.71.61.3
Condit. Reinf. inactive responses0.10.10.30.50.3-0.20.40.40.40.30.20.1
Incentive salience index mean2.02.53.21.51.8-1.51.61.61.61.61.51.4
Condit. Reinf. lever presses0.20.30.50.30.5-0.70.50.50.40.50.50.7
Condit. Reinf. active minus inactive responses0.81.11.3-1.2-0.91.0-1.0-1.0-1.0-1.0-1.0-1.0
Condit. Reinf. active-inactive response ratio0.50.60.9-1.0-0.90.8-0.8-0.7-1.0-0.6-0.6-0.5
Condit. Reinf. active responses0.50.70.9-0.9-0.60.8-0.8-0.8-0.8-0.8-0.8-0.9
Condit. Reinf. inactive responses0.10.10.40.40.6-0.20.30.20.30.20.1-0.0
Condit. Reinf. lever presses2.33.14.11.61.8-2.01.81.81.61.91.91.5
Condit. Reinf. lever reinforcers received0.10.10.3-0.4-0.20.2-0.3-0.3-0.2-0.3-0.3-0.5
Conditioned reinforcement - actives0.30.51.51.20.8-0.30.80.70.50.50.40.3
Conditioned reinforcement - inactives0.10.20.8-0.50.30.50.0-0.20.9-0.2-0.2-0.5
Conditioned locomotion0.50.71.2-1.1-0.60.7-0.7-0.90.1-1.0-1.0-0.9
Patch foraging indifference point 0 sec3.46.37.8-2.3-2.52.8-2.5-2.6-2.2-2.6-2.7-2.5
Patch foraging indifference point AUC1.52.23.7-1.6-1.71.5-1.7-1.5-1.9-1.3-1.2-0.7
Delay disc. indifference point, 0s delay0.50.51.20.90.6-0.60.80.71.10.50.40.5
Delay disc. indifference point, 16s delay0.80.93.2-0.3-0.60.7-0.7-0.8-0.6-1.1-1.2-1.8
Delay disc. indifference point, 2s delay0.30.30.8-0.7-0.00.5-0.2-0.40.9-0.5-0.6-0.7
Delay disc. indifference point, 24s delay0.20.31.3-0.0-0.10.6-0.2-0.30.1-0.5-0.6-1.1
Delay disc. indifference point, 4s delay0.40.40.90.40.8-0.60.60.60.90.50.50.5
Delay disc. indifference point, 8s delay0.10.20.60.10.0-0.3-0.1-0.30.3-0.5-0.6-0.8
Indifference point function ln k0.20.31.00.60.8-0.20.60.51.00.30.3-0.2
Indifference point function log k0.20.31.00.60.8-0.20.60.51.00.30.3-0.2
Patch foraging total patch changes 0 sec3.46.47.8-2.3-2.52.8-2.5-2.6-2.1-2.6-2.7-2.5
Patch foraging total patch changes 12 sec3.03.94.2-1.9-2.02.1-2.0-2.0-2.0-1.9-1.9-1.8
Patch foraging total patch changes 18 sec2.94.45.1-2.0-2.22.3-2.1-2.2-1.9-2.2-2.2-1.9
Patch foraging total patch changes 24 sec0.10.20.6-0.8-0.5-0.1-0.5-0.4-0.6-0.3-0.20.1
Patch foraging total patch changes 6 sec1.72.63.3-1.8-1.71.5-1.7-1.7-1.6-1.6-1.6-1.1
Patch foraging time to switch 0 sec0.81.61.81.11.4-1.41.31.31.21.31.21.0
Patch foraging water rate 0 sec1.53.14.2-1.6-2.01.8-1.8-1.8-1.8-1.8-1.8-1.4
Patch foraging water rate 12 sec0.10.20.5-0.5-0.50.3-0.4-0.60.1-0.6-0.7-0.3
Patch foraging water rate 18 sec0.10.10.3-0.5-0.10.2-0.2-0.40.3-0.5-0.5-0.4
Patch foraging water rate 24 sec0.10.10.20.1-0.30.1-0.2-0.3-0.2-0.3-0.3-0.4
Patch foraging water rate 6 sec0.40.61.3-1.1-0.90.5-0.9-0.9-0.6-0.8-0.7-0.6
Seeking ratio, delayed vs. immediate footshock2.83.44.3-1.8-1.81.8-1.8-1.9-1.3-2.0-2.0-2.1
Distance traveled before self-admin0.30.42.0-1.40.20.6-0.3-0.31.10.00.10.2
Distance traveled after self-admin0.10.10.2-0.5-0.1-0.1-0.2-0.20.3-0.2-0.2-0.4
Extensor digitorum longus weight0.62.42.81.61.6-1.21.61.71.21.71.71.6
Bone: elastic displacement1.61.82.3-1.3-1.51.1-1.4-1.4-1.4-1.3-1.3-1.4
Bone: elastic work0.40.50.9-0.8-0.90.4-0.8-0.7-0.9-0.7-0.6-0.5
Bone: endosteal estimation0.20.40.9-0.3-0.30.9-0.5-0.6-0.4-0.8-0.8-1.0
Bone: endosteal perimeter0.30.71.0-0.6-0.70.9-0.8-0.9-0.5-1.0-1.0-0.9
Epididymis fat weight2.27.59.3-2.7-2.63.0-2.7-2.9-2.1-2.9-3.0-2.7
Delta time in closed arm before/after self-admin0.30.20.7-0.3-0.50.3-0.5-0.5-0.8-0.5-0.5-0.2
Delta time in open arm before/after self-admin0.60.61.40.00.8-0.80.60.61.20.80.90.5
Diff in mean of infusions in LGA sessions0.91.11.90.81.0-1.40.90.91.21.01.01.0
Delay discount exponential model param0.20.20.8-0.1-0.2-0.1-0.00.2-0.50.40.60.9
Extinction: sum of active levers before priming0.60.71.21.10.7-0.80.90.90.60.80.90.5
Active lever presses in extinction session 60.10.10.3-0.0-0.30.3-0.2-0.2-0.6-0.2-0.2-0.5
Bone: final force0.81.31.51.01.2-1.21.21.21.01.21.21.2
Bone: final moment0.40.60.70.60.8-0.80.80.80.60.80.80.8
Food consumed during 24 hour testing period1.11.53.3-0.4-0.81.7-0.9-1.1-0.7-1.3-1.4-1.8
Glucose1.72.73.41.71.8-1.51.71.71.61.61.61.4
Heart weight0.00.00.10.10.2-0.10.20.20.30.20.10.2
Delay discount hyperbolic model param0.10.20.6-0.2-0.30.1-0.20.1-0.80.30.40.7
Intermittent access intake day 1-15 change0.61.13.11.71.0-0.71.31.11.20.80.60.5
Intermittent access intake escalation0.71.43.31.81.2-0.81.41.31.21.00.80.6
Intermittent access intake escalation 20.40.41.51.20.6-0.40.80.70.40.50.40.1
Intermitt. access day 1 inactive lever presses0.00.20.70.3-0.00.40.0-0.20.2-0.4-0.5-0.8
Intermitt. access day 15 inactive lever presses0.20.41.80.20.7-0.30.60.51.30.40.40.3
Intermitt. access escalation Index0.30.41.0-0.6-1.00.4-0.6-0.6-0.8-0.7-0.6-0.2
Intermittent access day 1 total infusions0.10.10.30.4-0.30.2-0.1-0.2-0.6-0.3-0.4-0.4
Intermittent access day 15 total infusions0.60.93.41.90.8-0.61.21.00.90.60.40.3
Intermittent access terminal intake (last 3 days)1.21.64.72.21.2-0.61.61.31.20.90.70.5
Intermittent access total infusions0.91.03.51.90.8-0.71.21.10.70.70.60.6
Intermittent access day 1 locomotion1.62.12.5-1.1-1.51.3-1.4-1.5-1.5-1.6-1.6-1.5
Intermittent access day 15 total locomotion0.30.51.0-0.5-0.60.8-0.6-0.7-0.5-0.8-0.9-1.0
Intermittent access total locomotion0.10.10.2-0.2-0.30.3-0.2-0.3-0.2-0.4-0.5-0.5
Intermittent access standard deviation0.20.51.2-0.5-0.60.6-0.5-0.70.2-0.9-1.1-0.7
Left kidney weight1.57.111.52.42.8-2.62.82.63.42.52.42.3
Right kidney weight1.67.310.62.42.8-2.72.82.63.32.62.52.5
Cocaine induced anxiety1.92.83.8-2.0-1.91.7-1.7-1.7-1.4-1.6-1.6-1.1
Post-drug Anxiety0.50.50.8-0.7-0.50.7-0.6-0.8-0.2-0.8-0.9-0.8
Baseline Anxiety1.01.12.41.51.5-1.01.11.01.00.80.70.0
Tail length0.10.30.60.0-0.60.5-0.3-0.4-0.8-0.5-0.6-0.6
Length with tail0.20.81.1-0.8-1.01.0-0.8-0.9-0.8-1.0-1.0-0.7
Length without tail0.51.72.2-1.4-1.31.5-1.3-1.4-0.9-1.4-1.5-1.2
Times rat made contact with spout1.92.22.6-1.2-1.41.4-1.5-1.5-1.6-1.6-1.6-1.6
Lifetime Intake0.70.83.01.70.7-0.71.10.90.60.60.50.5
Liver weight, left0.20.20.5-0.7-0.50.3-0.5-0.6-0.3-0.6-0.6-0.3
Liver weight, right0.61.01.2-0.8-1.01.0-1.0-1.0-0.9-1.1-1.1-1.0
Locomotor activity1.92.94.9-2.2-1.81.6-1.9-1.8-1.9-1.5-1.4-1.0
Locomotor testing distance1.73.14.2-2.0-1.91.4-1.9-1.8-2.1-1.6-1.6-1.2
Locomotor testing rearing0.10.10.6-0.8-0.30.3-0.5-0.4-0.3-0.2-0.10.1
Locomotion in novel chamber2.32.94.0-1.9-1.62.0-1.7-1.7-1.6-1.6-1.5-1.7
Locomotion in novel chamber post-restriction2.03.35.5-1.6-2.01.7-1.9-1.7-2.3-1.7-1.6-1.6
Fecal boli incidents, locomotor time 11.52.26.0-0.9-1.91.2-1.5-1.3-2.5-1.3-1.3-0.8
Change in fecal boli incidents, locomotor task0.60.61.30.71.0-0.50.80.71.10.60.60.2
Time >=10cm from walls, locomotor time 10.91.03.1-0.2-1.10.5-0.9-0.9-1.8-0.9-0.9-0.9
Bouts of movement, locomotor time 10.10.20.7-0.1-0.50.5-0.3-0.2-0.9-0.1-0.1-0.1
Total resting periods, locomotor time 10.10.10.50.2-0.20.30.00.1-0.70.20.20.2
Rest time, locomotor task time 10.40.61.60.50.1-0.30.40.7-0.70.91.01.2
Distance moved, locomotor task time 10.20.41.0-0.5-0.20.5-0.4-0.60.2-0.7-0.8-1.0
Vertical activity count, locomotor time 10.92.13.2-1.1-1.21.7-1.3-1.4-0.9-1.7-1.8-1.8
Time >=10cm from walls, locomotor time 20.50.81.30.90.6-1.00.60.8-0.11.01.11.1
Bouts of movement, locomotor time 20.60.91.21.10.9-0.51.01.00.91.01.01.1
Total resting periods, locomotor time 20.71.21.71.21.1-0.61.11.21.01.21.21.3
Rest time, locomotor task time 20.30.41.21.10.3-0.30.60.8-0.40.70.70.6
Distance moved, locomotor task time 20.30.31.1-1.0-0.30.4-0.6-0.60.3-0.5-0.4-0.4
Vertical activity count, locomotor time 20.91.21.7-1.3-0.91.3-1.1-1.1-0.6-1.1-1.1-1.1
Light reinforcement 12.15.26.8-2.6-2.42.3-2.4-2.4-1.8-2.3-2.2-2.2
Light reinforcement 22.33.64.4-2.0-1.91.7-1.9-1.9-1.8-1.8-1.8-2.1
Bone: marrow area0.20.40.8-0.2-0.30.8-0.4-0.5-0.3-0.7-0.7-0.9
Bone: maximum diameter0.50.91.1-1.0-1.01.0-1.0-1.0-0.8-1.0-1.0-0.8
Bone: maximum force0.40.71.40.50.8-1.00.80.80.60.90.91.2
Bone: maximum moment0.10.20.50.10.4-0.60.30.40.20.40.50.7
Mean time between licks in bursts0.00.10.3-0.2-0.20.2-0.1-0.20.2-0.3-0.4-0.6
Mean num. licks in bursts0.10.10.50.2-0.20.4-0.1-0.2-0.3-0.4-0.5-0.7
Cd content in liver0.20.20.30.10.5-0.00.40.40.50.50.50.4
Co content in liver0.00.00.20.30.1-0.10.20.2-0.00.20.20.4
Cu content in liver0.60.71.21.10.9-0.40.90.90.70.90.80.7
Fe content in liver1.82.23.8-1.4-1.81.4-1.6-1.4-2.0-1.3-1.2-1.1
K content in liver0.10.10.20.50.3-0.10.20.10.30.0-0.0-0.1
Mg content in liver0.60.71.0-0.5-0.80.8-0.8-0.8-0.7-0.9-0.9-1.0
Mn content in liver0.60.71.1-0.8-0.70.6-0.8-0.9-0.5-1.0-1.0-1.0
Na content in liver0.00.00.00.20.1-0.00.00.0-0.20.10.10.2
Rb content in liver0.10.10.30.60.3-0.00.40.40.30.30.30.3
Se content in liver0.10.10.50.20.2-0.50.20.3-0.00.40.40.7
Sr content in liver1.31.11.4-1.0-0.91.0-1.0-1.1-0.7-1.2-1.2-1.2
Zn content in liver1.21.42.31.51.3-0.71.31.21.31.11.00.9
Bone: minimum diameter0.10.20.3-0.5-0.50.5-0.5-0.4-0.6-0.4-0.4-0.2
Time in familiar zone, hab. session 10.20.20.4-0.6-0.30.3-0.3-0.4-0.3-0.4-0.5-0.7
Time in novel zone, hab. session 10.30.30.70.60.4-0.60.40.50.30.60.60.8
Total zone transitions, hab. session 11.01.31.4-1.1-1.21.2-1.2-1.2-1.1-1.2-1.2-1.2
Total locomotion distance, hab. session 11.21.82.0-1.2-1.31.3-1.3-1.4-1.2-1.4-1.4-1.4
Locomotion velocity, hab. session 11.72.32.6-1.3-1.51.6-1.5-1.6-1.4-1.6-1.6-1.6
Time in familiar zone, hab. session 20.60.61.2-1.1-0.90.6-0.8-0.8-0.7-0.7-0.7-0.7
Time in novel zone, hab. session 24.64.75.52.32.1-2.22.22.21.82.22.22.2
Total zone transitions, hab. session 22.12.83.4-1.7-1.91.4-1.7-1.7-1.8-1.6-1.7-1.3
Total locomotion distance, hab. session 21.51.92.1-1.3-1.51.3-1.4-1.4-1.4-1.4-1.5-1.3
Locomotion velocity, hab. session 21.41.82.1-1.3-1.51.3-1.4-1.4-1.4-1.4-1.4-1.3
Novel to familiar place preference ratio2.62.83.31.61.8-1.61.71.71.81.71.71.5
Novelty place preference4.14.44.82.02.2-2.12.12.12.22.12.11.9
Time in novel zone, NPP test3.84.04.41.92.1-2.02.02.02.12.02.01.8
Total zone transitions, NPP test1.92.73.5-1.6-1.91.5-1.7-1.7-1.8-1.6-1.6-1.4
Total locomotion distance, NPP test1.11.52.0-1.1-1.41.0-1.3-1.2-1.4-1.2-1.2-1.1
Locomotion velocity, NPP test0.91.31.9-1.0-1.40.9-1.2-1.2-1.4-1.1-1.1-1.0
Intraocular pressure0.71.01.30.51.0-0.90.91.01.11.01.11.0
Delta distance traveled before/after self-admin0.40.40.90.80.7-1.00.60.50.80.40.3-0.1
Delta ambulatory time before/after self-admin0.40.51.31.10.7-1.10.70.60.60.40.3-0.1
Parametrial fat weight6.615.418.2-4.3-4.14.0-4.0-3.9-4.0-3.8-3.7-3.5
Pavlov. Cond. lever latency0.10.10.5-0.1-0.20.6-0.2-0.3-0.3-0.4-0.4-0.7
Pavlov. Cond. magazine entry latency0.30.40.50.70.7-0.70.60.60.50.60.50.6
Pavlov. Cond. change in total contacts0.91.01.20.81.0-1.11.01.01.01.01.01.1
Pavlov. Cond. index score0.30.40.60.40.6-0.80.50.50.70.50.50.7
Pavlov. Cond. latency score0.20.30.50.30.5-0.70.50.40.50.50.50.7
Pavlov. Cond. lever contacts0.60.71.30.70.7-1.10.80.80.70.90.91.1
Pavlov. Cond. magazine entry number0.30.40.7-0.8-0.70.7-0.7-0.6-0.7-0.5-0.5-0.5
Pavlov. Cond. intertrial magazine entries0.30.30.7-0.4-0.40.8-0.5-0.5-0.5-0.6-0.5-0.8
Pavlov. Cond. lever-magazine prob. diff.0.30.40.60.50.7-0.80.60.60.70.60.60.7
Pavlov. Cond. response bias0.20.20.50.50.5-0.70.50.40.40.40.40.5
Pavlov. Cond. lever latency1.21.62.2-1.3-1.21.5-1.3-1.3-1.1-1.3-1.3-1.0
Pavlov. Cond. magazine entry latency3.34.05.62.02.0-2.42.12.01.82.02.01.7
Pavlov. Cond. change in total contacts1.82.83.71.51.7-1.91.71.71.61.81.81.5
Pavlov. Cond. index score3.24.25.82.12.0-2.42.12.11.82.12.11.7
Pavlov. Cond. latency score3.24.36.02.02.1-2.42.12.11.92.12.11.7
Pavlov. Cond. lever contacts1.31.82.31.41.3-1.51.41.41.11.41.41.0
Pavlov. Cond. magazine entry number5.56.89.0-2.5-2.73.0-2.7-2.6-2.4-2.6-2.6-2.3
Pavlov. Cond. intertrial magazine entries4.66.98.1-2.6-2.62.8-2.7-2.7-2.5-2.6-2.6-2.3
Pavlov. Cond. lever-magazine prob. diff.3.54.76.32.22.2-2.52.22.21.92.22.21.8
Pavlov. Cond. response bias2.83.84.62.01.9-2.12.02.01.82.02.01.5
Time in closed arm before self-admin3.24.16.4-1.9-2.02.5-2.0-2.0-1.6-2.0-2.1-1.9
Time in closed arm after self-admin2.42.53.8-1.9-1.71.5-1.7-1.7-1.3-1.6-1.6-0.9
Time in open arm before self-admin1.21.31.81.31.1-1.31.21.20.81.11.11.1
Time in open arm after self-admin1.01.01.50.71.0-1.21.01.00.91.21.20.8
Bone: periosteal estimation0.30.60.8-0.8-0.70.9-0.7-0.8-0.6-0.8-0.8-0.7
Bone: periosteal perimeter0.71.11.5-1.2-1.20.9-1.2-1.1-1.1-1.1-1.0-0.6
Bone: post-yield work0.30.51.1-1.1-0.60.6-0.8-0.8-0.6-0.7-0.7-0.5
Progressive ratio test 1 active lever presses1.41.74.52.11.3-1.21.51.41.01.11.00.7
Progressive ratio test 1 breakpoint1.21.54.02.01.2-1.11.41.31.01.00.90.6
Progressive ratio test 1 inactive lever presses0.10.10.40.50.10.10.1-0.0-0.2-0.2-0.2-0.6
Progressive ratio test 2 active lever presses0.70.83.81.90.7-0.61.01.0-0.00.70.50.1
Progressive ratio test 2 breakpoint0.80.93.92.00.8-0.71.11.00.10.70.60.2
Progressive ratio test 2 inactive lever presses0.10.10.20.50.2-0.40.30.30.00.20.2-0.2
Incentive Sensitization - Responses0.20.31.61.30.10.00.40.5-0.70.30.2-0.1
Incentive Sensitization - Breakpoint0.30.31.81.30.1-0.00.50.5-0.70.30.3-0.0
Sum of active levers in priming session hrs 5-60.70.71.40.40.8-1.20.70.80.80.91.00.6
Progressive ratio0.50.81.8-0.50.7-1.40.50.51.00.91.01.1
Food seeking constrained by brief footshock1.92.33.91.31.6-2.01.51.41.61.41.41.5
Seeking ratio, punishment vs. effort0.20.31.41.20.5-0.30.60.50.40.30.20.1
Retroperitoneal fat weight6.025.530.6-5.5-5.24.9-5.2-5.2-4.9-5.0-4.9-4.6
Reaction time number correct0.61.22.31.51.2-0.21.21.11.31.00.90.8
Reaction time mean minus median1.12.63.51.01.8-1.81.51.51.81.61.61.9
Reaction time mean minus median AUC0.82.13.20.81.6-1.51.31.31.81.41.41.7
Reaction time num false alarms0.10.10.40.40.3-0.40.40.20.70.10.1-0.2
Reaction time num false alarms AUC0.10.10.50.1-0.30.1-0.2-0.3-0.0-0.4-0.5-0.7
Reaction time trials correct on left0.61.22.31.51.2-0.21.21.11.31.00.90.8
Reaction time trials on left0.61.22.41.61.2-0.11.21.11.30.90.90.8
Reaction time mean0.81.22.2-0.21.2-1.20.80.91.51.11.21.4
Reaction time mean AUC1.01.62.90.11.4-1.21.01.11.71.31.41.5
Median of all reaction times0.40.61.3-0.50.7-0.70.40.51.10.70.80.9
Reaction time omissions0.40.61.4-0.2-0.60.9-0.6-0.7-0.6-0.9-0.9-1.2
Reaction time false alarm rate0.40.50.8-0.7-0.80.0-0.7-0.8-0.6-0.8-0.8-0.9
Reaction time premature initiation rate1.52.02.21.31.5-1.51.41.41.41.51.51.3
Reaction time premature initiations2.13.84.52.12.1-1.52.12.02.02.01.91.7
Std. dev. reaction times0.81.42.40.21.3-1.41.01.01.31.31.31.6
Reaction time trials completed0.61.22.41.61.2-0.11.21.11.30.90.90.8
Reaction time trials AUC0.71.32.51.61.2-0.21.31.21.31.01.00.9
Run reversals in cocaine runway, females2.02.03.7-1.2-1.41.6-1.5-1.3-1.9-1.2-1.2-1.1
Run reversals in cocaine runway, males1.11.12.6-0.4-1.30.9-1.0-0.9-1.6-1.0-1.1-1.0
Latency to leave start box in cocaine runway0.40.41.30.40.8-0.30.70.61.10.60.60.4
Latency to leave start box in cocaine runway, F1.01.21.91.41.0-1.01.21.11.01.01.00.8
Latency to leave start box in cocaine runway, M0.40.42.1-1.5-0.10.8-0.5-0.50.4-0.3-0.2-0.3
Std. dev. time between licks in bursts2.02.73.1-1.7-1.71.8-1.7-1.7-1.4-1.6-1.6-1.5
Total sessions with >9 infusions0.40.52.41.50.5-0.40.90.70.70.40.20.1
Short access day 1 total inactive lever presses0.00.00.2-0.0-0.2-0.3-0.00.0-0.50.10.10.1
Short access day 10 total inactive lever presses0.10.40.6-0.5-0.50.8-0.5-0.6-0.4-0.6-0.7-0.7
Short access day 1 total infusions0.10.20.80.9-0.30.00.10.0-0.6-0.3-0.4-0.5
Short access day 10 total infusions0.10.10.60.8-0.20.10.20.1-0.2-0.2-0.4-0.3
Short access total infusions0.60.73.11.80.6-0.71.00.90.40.60.50.3
Short access day 1 locomotion0.10.10.50.7-0.3-0.00.1-0.0-0.3-0.2-0.4-0.5
Short access day 10 total locomotion1.32.43.0-1.7-1.51.5-1.6-1.6-1.2-1.6-1.6-1.6
Short access total locomotion0.40.50.9-0.6-0.70.7-0.6-0.7-0.2-0.8-0.9-0.8
One hour access (0.3 mA shock)0.30.41.71.30.4-0.50.70.6-0.00.40.20.3
Compulsive drug intake0.10.10.3-0.5-0.1-0.3-0.3-0.2-0.4-0.1-0.1-0.1
One hour access (shock baseline)0.30.42.21.50.3-0.20.70.70.10.40.20.3
Social response proportion0.10.20.60.80.5-0.10.50.40.30.1-0.0-0.2
Social responses0.10.20.6-0.1-0.00.0-0.2-0.40.2-0.6-0.8-0.5
Social time0.10.20.60.20.00.8-0.1-0.3-0.1-0.5-0.6-0.7
Soleus weight0.10.40.8-0.9-0.60.7-0.7-0.7-0.5-0.6-0.6-0.4
Bone: stiffness3.15.06.02.02.5-2.12.32.32.32.22.22.2
Tibialis anterior weight0.10.50.70.80.7-0.40.70.70.50.80.80.8
Time to tail flick, vehicle, before self-admin0.20.20.70.80.2-0.40.50.40.10.30.20.7
Time to tail flick, vehicle, after self-admin2.02.64.5-0.8-1.72.1-1.4-1.5-1.3-1.8-1.9-1.8
Time to tail flick, test, before self-admin5.15.27.8-1.8-2.32.8-2.1-2.1-2.4-2.2-2.2-2.6
Time to tail flick, test, after self-admin0.60.61.5-0.3-0.61.1-0.6-0.5-1.2-0.6-0.6-1.0
Delta time to tail flick, vehicle, before/after SA1.91.93.3-0.8-1.41.8-1.2-1.2-1.4-1.3-1.4-1.5
Delta time to tail flick, test, before/after SA0.90.91.61.10.9-1.31.00.90.80.90.90.9
Tibia length0.00.10.30.00.1-0.50.20.3-0.10.40.40.6
Ambulatory time before self-admin0.40.62.7-1.6-0.40.9-0.8-0.80.1-0.5-0.4-0.5
Ambulatory time after self-admin0.20.20.6-0.8-0.3-0.0-0.5-0.50.0-0.4-0.5-0.8
Bone: tissue strength0.30.30.50.60.6-0.70.60.60.50.60.50.5
Total heroin consumption1.01.21.61.31.2-0.71.21.21.01.21.20.7
Bone: trabecular number0.10.20.7-0.9-0.5-0.0-0.5-0.4-0.4-0.3-0.20.0
Bone: trabecular spacing0.40.51.2-0.2-0.31.1-0.4-0.5-0.4-0.7-0.8-1.1
Bone: trabecular thickness1.21.43.40.70.8-1.50.91.10.61.31.41.8
Bone: trabecular tissue density0.81.21.81.01.0-1.11.11.10.91.11.11.3
Water consumed over 24 hours0.50.71.2-0.6-0.51.0-0.8-0.8-0.8-0.9-0.9-1.1
Number of responses in last shaping day1.41.64.20.61.3-1.21.11.12.01.11.11.1