Hub : Genes

Catsper2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr3_108381675_108382153 0.12 0.06 7.1e-03 0.02 0.02 0.02 0.01 5.5e-03 2.0e-03 3.1e-03 5.3e-02
2 BLA isoform ratio XM_006234860.3 0.31 0.11 2.3e-04 0.02 0.07 0.06 0.05 2.4e-02 8.6e-05 6.6e-04 1.2e-03
3 PL isoform ratio XM_006234860.3 0.2 0.1 8.7e-04 0.02 0.04 0.05 0.02 4.0e-03 3.8e-05 6.7e-06 3.0e-03
4 IL gene expression Catsper2 0.16 0.09 3.2e-03 0.04 0.09 0.06 0.04 4.5e-02 4.1e-03 1.8e-02 3.1e-02
5 NAcc mRNA stability Catsper2 0.03 0.02 1.6e-04 0.03 0.03 0.03 0.04 1.0e-04 6.6e-04 8.5e-05 7.6e-06
6 BLA gene expression Catsper2 0.19 0.09 4.2e-09 0.12 0.12 0.1 0.12 8.4e-07 6.7e-07 4.0e-06 5.6e-07
7 NAcc gene expression Catsper2 0.51 0.2 1.6e-12 0.12 0.1 0.11 0.11 1.4e-13 1.3e-11 1.3e-12 5.9e-13
8 Liver gene expression Catsper2 0.12 0.07 7.8e-10 0.06 0.05 0.04 0.05 1.5e-07 1.5e-06 2.8e-05 2.1e-06
9 PL mRNA stability Catsper2 0.06 0.03 1.2e-09 0.1 0.07 0.08 0.08 9.6e-11 1.1e-08 3.2e-09 3.4e-09
10 PL gene expression Catsper2 0.15 0.07 0.0e+00 0.17 0.16 0.15 0.16 5.3e-18 9.9e-17 2.0e-16 8.8e-17
11 Brain gene expression Catsper2 0.1 0.05 7.4e-10 0.1 0.09 0.09 0.09 1.2e-09 1.3e-08 2.8e-08 1.0e-08
12 Brain mRNA stability Catsper2 0.12 0.06 1.7e-11 0.14 0.12 0.12 0.13 8.9e-13 7.2e-11 6.7e-11 7.5e-12
13 RMTg alternative TSS NM_001012220.1 0.11 0.07 8.2e-03 0.04 0.06 0.01 0.04 3.2e-02 1.1e-02 2.0e-01 3.9e-02
14 Liver mRNA stability Catsper2 0.11 0.06 7.6e-09 0.06 0.06 0.06 0.06 2.3e-07 3.3e-07 2.7e-07 4.9e-07
15 OFC gene expression Catsper2 0.37 0.17 1.2e-04 0.16 0.11 0.15 0.16 1.2e-04 1.5e-03 2.0e-04 1.6e-04
16 OFC mRNA stability Catsper2 0.41 0.17 1.2e-04 0.2 0.09 0.15 0.14 2.1e-05 3.5e-03 2.2e-04 3.5e-04
17 BLA mRNA stability Catsper2 0.19 0.12 7.2e-05 0.04 0.05 0.07 0.04 4.9e-03 1.8e-03 1.6e-04 2.2e-03
18 NAcc isoform ratio XM_006234860.3 0.11 0.06 7.5e-03 0.03 0.02 0.03 0.03 1.5e-04 8.0e-04 3.0e-04 2.2e-04
19 BLA intron excision ratio chr3_108381675_108382153 0.28 0.11 2.4e-03 0.06 0.05 0.05 0.05 3.1e-04 1.3e-03 9.3e-04 1.2e-03
20 BLA intron excision ratio chr3_108381675_108382273 0.28 0.11 2.4e-03 0.06 0.05 0.05 0.05 2.8e-04 1.4e-03 9.5e-04 1.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.40.62.0-0.20.1-0.3-0.9-1.4-1.00.91.00.90.80.90.9-0.80.60.90.90.5-0.30.4-0.4
Area under the delay curve1.41.59.62.6-3.12.70.00.40.3-0.8-0.6-0.7-0.6-0.7-0.70.6-0.7-0.9-0.9-0.6-0.00.0-0.0
BMI with tail0.10.32.80.8-0.9-0.0-0.2-1.7-0.30.50.60.40.70.60.6-0.2-0.20.20.20.20.00.1-0.1
BMI without tail1.42.87.5-0.80.8-1.8-1.9-2.7-2.21.81.81.71.91.81.8-1.51.31.91.92.0-0.00.0-0.0
Body weight0.10.31.6-1.00.6-1.00.5-1.30.1-0.2-0.1-0.3-0.0-0.1-0.10.5-1.2-0.0-0.0-0.2-0.40.4-0.4
Weight adjusted by age0.80.92.2-0.80.6-0.21.01.30.7-1.2-1.5-1.1-1.5-1.0-1.01.4-1.2-0.8-0.8-0.40.2-0.10.1
Bone surface0.20.31.10.2-0.10.0-0.4-1.1-0.40.70.80.70.70.70.7-0.60.50.50.50.20.00.1-0.1
Bone volume0.30.51.11.0-0.60.2-0.4-1.0-0.30.80.90.80.80.80.8-0.70.50.40.40.40.7-0.60.6
Breakpoint value in progressive ratio session1.51.77.32.7-1.80.6-0.9-1.0-0.61.61.61.61.51.51.5-1.30.90.60.61.00.8-0.80.8
Number of licking bursts1.31.55.02.2-1.71.1-1.2-1.1-0.71.31.31.31.21.31.3-1.41.60.70.70.60.9-0.90.9
Context. condit. distance diff. score1.21.55.4-1.82.1-2.3-0.8-1.4-1.11.01.01.01.01.01.0-0.70.61.31.31.30.6-0.60.6
Locomotion velocity, session 10.20.20.90.6-0.70.1-0.01.0-0.0-0.5-0.6-0.5-0.3-0.5-0.50.5-0.7-0.4-0.40.20.20.0-0.0
Locomotion distance, session 10.10.20.7-0.80.5-0.9-0.50.3-0.7-0.0-0.0-0.0-0.0-0.0-0.00.0-0.30.40.40.7-0.40.4-0.4
Locomotion velocity, session 20.10.10.60.3-0.80.1-0.7-0.5-0.6-0.1-0.2-0.1-0.0-0.1-0.10.2-0.20.10.10.70.0-0.30.3
Locomotion distance, session 20.71.02.3-1.31.0-1.0-1.3-0.9-1.50.90.90.90.90.90.9-0.90.61.41.41.0-0.70.6-0.6
Locomotion velocity, session 31.92.27.32.7-2.52.30.51.01.2-0.9-0.9-0.9-0.9-0.9-0.90.9-0.4-1.6-1.6-0.41.8-1.91.9
Locomotion distance, session 31.92.19.62.3-1.20.5-0.7-0.2-0.10.70.70.70.80.70.7-0.50.90.00.01.43.1-3.13.1
Stereotopy head waving bouts, day 31.41.63.00.4-0.60.41.31.01.4-1.6-1.6-1.6-1.7-1.6-1.61.7-1.4-1.6-1.6-0.70.5-0.50.5
Stereotopy head waving duration, day 31.61.93.30.7-1.51.21.10.71.2-1.8-1.7-1.8-1.8-1.8-1.81.7-1.5-1.7-1.7-1.1-0.40.3-0.3
Locomotion velocity, session 70.91.04.4-0.20.9-1.3-0.6-0.2-0.50.30.40.30.20.30.3-0.00.10.40.41.62.1-2.02.0
Locomotion distance, session 71.01.34.8-1.92.2-1.8-0.9-0.8-1.00.90.90.90.90.90.9-0.80.91.31.31.10.4-0.40.4
Stereotopy head waving bouts, day 71.31.52.80.4-0.50.91.51.31.7-1.4-1.4-1.4-1.4-1.4-1.41.3-1.1-1.6-1.6-1.5-0.0-0.20.2
Stereotopy head waving duration, day 71.82.23.91.7-1.51.61.71.62.0-1.4-1.5-1.4-1.4-1.4-1.41.5-1.3-2.0-2.0-1.40.6-0.80.8
Locomotion velocity, session 80.30.41.7-0.50.4-1.0-0.7-0.7-0.80.10.00.10.10.10.10.2-0.40.50.51.30.9-0.90.9
Locomotion distance, session 81.52.27.4-2.72.7-2.6-1.3-1.4-1.61.01.11.01.11.01.0-0.90.71.71.71.60.2-0.20.2
Degree of sensitization distance1.41.47.7-2.82.3-1.10.50.1-0.1-0.1-0.1-0.1-0.2-0.1-0.1-0.0-0.20.50.5-0.8-2.12.1-2.1
Degree of sensitization stereotypy0.80.92.20.5-0.20.41.31.31.5-0.9-1.0-0.9-0.9-0.9-0.90.9-0.8-1.2-1.2-1.00.6-0.80.8
Conditioned locomotion0.40.41.9-1.41.3-1.3-0.5-1.0-0.60.30.50.20.30.30.3-0.40.30.60.60.5-0.20.0-0.0
Cocaine response after cond. corrected3.33.710.13.2-2.52.3-1.9-1.7-1.42.12.02.02.02.12.1-2.02.31.11.11.41.2-1.41.4
Cocaine response after cond. not corrected2.73.07.42.7-2.52.4-1.9-1.6-1.51.91.71.81.81.91.9-1.82.01.11.11.10.5-0.80.8
Cocaine response before conditioning0.60.82.9-1.71.0-0.80.50.70.1-0.9-1.1-0.9-1.0-0.9-0.90.9-1.1-0.2-0.2-0.3-1.00.9-0.9
Saline control response2.63.45.3-2.21.5-0.82.11.71.8-2.3-2.2-2.3-2.2-2.3-2.32.2-2.0-1.7-1.7-1.7-1.00.8-0.8
Bone: connectivity density0.20.41.7-1.20.6-0.40.2-0.3-0.2-0.2-0.1-0.1-0.2-0.2-0.20.1-0.40.20.2-0.5-1.21.3-1.3
Bone: cortical apparent density0.40.51.51.2-0.40.4-0.2-0.10.00.91.00.91.00.90.9-0.81.10.20.20.20.8-0.60.6
Bone: cortical area0.20.21.41.2-0.8-0.1-0.0-0.50.10.20.20.20.10.20.20.1-0.3-0.1-0.10.51.0-0.70.7
Bone: cortical porosity0.91.03.20.3-0.6-0.4-1.8-1.1-1.80.90.91.01.00.90.9-0.90.91.21.21.5-0.1-0.00.0
Bone: cortical porosity0.30.31.30.3-0.6-0.4-1.1-0.6-1.00.30.20.30.30.30.3-0.30.30.60.61.10.2-0.30.3
Bone: cortical thickness0.20.31.00.8-0.5-0.6-0.5-0.8-0.50.50.60.50.50.50.5-0.20.00.40.41.00.8-0.50.5
Bone: cortical thickness1.41.77.52.7-2.41.9-0.9-1.1-0.41.21.21.21.31.21.2-1.41.50.30.30.10.6-0.40.4
Bone: cortical tissue density0.40.51.91.4-0.60.6-0.1-0.10.10.90.90.90.90.90.9-0.81.10.10.10.10.8-0.60.6
Condit. Reinf. active minus inactive responses1.21.43.1-1.11.5-0.81.81.71.6-1.1-1.2-1.1-1.1-1.1-1.11.3-1.3-1.1-1.1-1.00.2-0.20.2
Condit. Reinf. active-inactive response ratio0.70.71.50.10.3-0.31.21.01.2-0.8-0.9-0.8-0.8-0.8-0.81.0-1.0-1.0-1.0-0.40.9-0.90.9
Condit. Reinf. active responses1.62.05.6-2.02.4-1.22.12.21.7-1.3-1.3-1.3-1.3-1.3-1.31.3-1.4-1.0-1.0-1.3-0.30.3-0.3
Condit. Reinf. inactive responses0.50.64.6-1.82.1-1.20.81.10.5-0.3-0.2-0.3-0.3-0.3-0.30.2-0.30.00.0-0.4-0.40.4-0.4
Incentive salience index mean1.51.94.2-1.81.9-0.81.92.11.6-1.4-1.4-1.4-1.3-1.4-1.41.3-1.5-1.1-1.1-1.4-0.60.5-0.5
Condit. Reinf. lever presses1.62.16.0-2.42.1-0.91.61.81.2-1.4-1.3-1.4-1.4-1.4-1.41.2-1.5-0.8-0.8-1.4-1.51.2-1.2
Condit. Reinf. active minus inactive responses1.21.56.7-2.62.2-1.01.40.30.9-0.7-0.7-0.7-0.8-0.7-0.70.6-0.8-0.2-0.2-1.6-1.61.7-1.7
Condit. Reinf. active-inactive response ratio0.70.73.5-1.91.7-0.90.8-0.00.4-0.2-0.1-0.1-0.3-0.2-0.20.1-0.30.10.1-1.0-1.31.3-1.3
Condit. Reinf. active responses1.41.97.1-2.72.3-0.81.90.71.4-1.1-1.2-1.0-1.1-1.1-1.11.0-1.0-0.6-0.6-1.8-1.21.4-1.4
Condit. Reinf. inactive responses1.82.34.9-1.00.70.42.21.52.1-1.7-1.9-1.7-1.7-1.7-1.71.7-1.4-1.7-1.7-1.9-0.30.4-0.4
Condit. Reinf. lever presses3.24.48.2-0.70.30.82.92.22.8-2.4-2.6-2.3-2.5-2.4-2.42.3-2.1-2.3-2.3-2.8-0.70.9-0.9
Condit. Reinf. lever reinforcers received2.02.99.7-3.12.6-0.92.21.11.7-1.4-1.6-1.3-1.5-1.4-1.41.4-1.3-0.9-0.9-2.2-1.61.7-1.7
Conditioned reinforcement - actives0.80.81.7-1.30.8-0.70.80.90.5-1.1-1.0-1.1-1.0-1.0-1.01.0-1.2-0.6-0.6-0.6-0.70.8-0.8
Conditioned reinforcement - inactives0.80.82.6-1.01.6-1.3-0.6-0.6-0.60.80.70.80.50.90.9-0.50.90.80.81.30.9-1.01.0
Conditioned locomotion2.53.05.2-2.21.2-0.81.51.91.1-2.3-2.1-2.3-2.1-2.2-2.22.1-2.2-1.3-1.3-1.3-0.91.0-1.0
Patch foraging indifference point 0 sec6.610.617.10.6-1.01.63.73.53.7-4.0-4.1-4.0-4.0-4.0-4.04.1-3.7-3.9-3.9-2.60.7-1.01.0
Patch foraging indifference point AUC0.00.10.60.3-0.10.10.10.80.20.00.2-0.0-0.0-0.0-0.0-0.20.1-0.2-0.2-0.3-0.10.1-0.1
Delay disc. indifference point, 0s delay2.32.54.11.6-2.02.01.41.71.5-1.8-1.7-1.7-1.7-1.7-1.71.7-1.8-1.8-1.8-1.20.2-0.60.6
Delay disc. indifference point, 16s delay2.82.815.13.6-3.93.70.40.61.0-1.0-0.9-0.9-1.0-1.0-1.00.8-0.5-1.5-1.5-1.00.6-0.70.7
Delay disc. indifference point, 2s delay0.20.21.0-0.91.0-1.0-0.20.0-0.2-0.00.20.10.2-0.0-0.0-0.10.10.30.30.3-0.1-0.10.1
Delay disc. indifference point, 24s delay0.90.83.70.8-1.51.90.50.50.6-0.9-0.7-0.9-0.8-0.9-0.90.6-0.7-0.8-0.8-1.1-0.60.8-0.8
Delay disc. indifference point, 4s delay0.20.21.30.5-1.11.0-0.4-0.2-0.3-0.4-0.4-0.5-0.4-0.3-0.30.2-0.1-0.2-0.2-0.1-0.40.3-0.3
Delay disc. indifference point, 8s delay2.62.717.13.9-4.13.20.30.80.5-0.8-0.6-0.7-0.6-0.7-0.70.9-1.2-1.3-1.3-0.30.7-0.50.5
Indifference point function ln k0.60.93.20.1-0.1-0.1-1.0-1.8-1.11.11.01.11.01.11.1-0.80.91.01.01.10.4-0.20.2
Indifference point function log k0.60.93.20.1-0.1-0.1-1.0-1.8-1.11.11.01.11.01.11.1-0.80.91.01.01.10.4-0.20.2
Patch foraging total patch changes 0 sec6.510.516.10.9-1.21.83.73.53.8-3.9-4.0-3.9-3.9-3.9-3.94.0-3.5-4.0-4.0-2.60.8-1.21.2
Patch foraging total patch changes 12 sec3.84.99.0-0.20.20.12.73.02.7-2.8-2.5-2.7-2.6-2.7-2.72.6-2.6-2.6-2.6-1.80.4-0.70.7
Patch foraging total patch changes 18 sec1.51.94.5-0.40.5-0.11.62.11.7-1.7-1.5-1.7-1.7-1.6-1.61.5-1.1-1.7-1.7-1.00.6-0.60.6
Patch foraging total patch changes 24 sec2.93.65.5-0.7-0.31.12.01.71.9-2.3-2.2-2.3-2.3-2.3-2.32.0-2.0-2.1-2.1-2.3-1.31.3-1.3
Patch foraging total patch changes 6 sec2.33.56.40.3-0.10.52.22.52.3-2.2-2.1-2.2-2.2-2.2-2.22.2-1.9-2.2-2.2-1.31.1-1.31.3
Patch foraging time to switch 0 sec1.01.52.6-1.10.9-0.21.61.61.4-1.4-1.3-1.3-1.4-1.4-1.41.3-1.4-1.2-1.2-1.4-0.50.7-0.7
Patch foraging water rate 0 sec0.20.41.50.9-0.4-0.1-0.2-0.50.20.30.60.30.60.40.4-0.40.5-0.0-0.00.31.1-1.21.2
Patch foraging water rate 12 sec3.14.88.72.6-1.80.6-2.2-2.5-1.82.73.02.73.02.72.7-2.72.41.91.91.60.9-1.01.0
Patch foraging water rate 18 sec1.62.16.12.5-2.01.3-1.3-1.7-1.01.41.41.51.51.51.5-1.21.20.90.91.21.3-1.31.3
Patch foraging water rate 24 sec1.72.45.92.4-1.10.6-0.8-1.2-0.31.61.81.61.81.71.7-1.41.50.70.71.12.1-2.32.3
Patch foraging water rate 6 sec2.63.86.82.1-1.00.2-1.8-1.9-1.32.52.62.62.62.52.5-2.42.31.71.71.51.2-1.21.2
Seeking ratio, delayed vs. immediate footshock0.91.17.9-2.72.8-1.80.1-0.2-0.10.30.30.40.30.30.3-0.30.40.80.8-0.0-0.50.3-0.3
Distance traveled before self-admin0.10.10.4-0.30.10.10.20.10.0-0.00.00.00.0-0.2-0.2-0.0-0.20.10.1-0.6-0.60.6-0.6
Distance traveled after self-admin0.20.21.60.7-0.51.30.30.20.6-0.00.20.00.20.10.1-0.40.6-0.4-0.4-1.10.0-0.00.0
Extensor digitorum longus weight0.20.82.91.7-1.10.3-0.4-0.7-0.30.60.40.60.40.60.6-0.10.20.10.11.11.7-1.51.5
Bone: elastic displacement0.40.51.41.2-0.90.20.40.80.5-0.5-0.6-0.6-0.5-0.5-0.50.7-0.7-0.7-0.70.20.9-1.01.0
Bone: elastic work0.91.12.11.5-1.00.41.11.01.2-0.9-0.9-0.9-0.9-0.9-0.91.1-1.1-1.3-1.3-0.31.2-1.21.2
Bone: endosteal estimation0.10.20.30.2-0.00.2-0.3-0.5-0.20.50.50.50.50.50.5-0.50.60.30.30.10.1-0.20.2
Bone: endosteal perimeter0.00.00.20.5-0.20.2-0.0-0.10.10.10.10.10.10.10.1-0.1-0.10.00.00.10.2-0.30.3
Epididymis fat weight0.10.20.8-0.30.5-0.90.40.30.4-0.5-0.2-0.5-0.2-0.4-0.40.5-0.6-0.4-0.40.20.6-0.60.6
Delta time in closed arm before/after self-admin1.31.27.2-2.32.7-2.6-0.4-0.2-0.60.50.50.40.50.50.5-0.30.30.90.91.20.5-0.30.3
Delta time in open arm before/after self-admin1.91.93.9-0.81.2-1.2-1.5-1.6-1.31.61.61.61.61.51.5-1.62.01.61.61.20.1-0.20.2
Diff in mean of infusions in LGA sessions0.10.10.5-0.60.7-0.50.70.50.5-0.1-0.2-0.2-0.1-0.2-0.20.3-0.5-0.3-0.3-0.30.00.1-0.1
Delay discount exponential model param0.91.06.9-2.12.6-2.30.2-0.1-0.00.60.40.50.40.50.5-0.30.40.60.60.40.2-0.20.2
Extinction: sum of active levers before priming0.80.86.12.5-2.21.2-0.3-0.4-0.00.40.50.50.40.40.4-0.40.2-0.3-0.30.30.5-0.60.6
Active lever presses in extinction session 60.60.62.20.3-0.3-0.6-1.1-1.1-1.10.90.60.80.70.70.7-0.50.30.90.91.50.2-0.20.2
Bone: final force0.40.73.60.10.8-1.9-0.2-0.6-0.20.60.60.60.60.60.6-0.2-0.00.40.41.21.5-1.31.3
Bone: final moment0.50.82.80.30.6-1.7-0.2-0.5-0.20.70.60.60.60.70.7-0.20.00.40.41.31.7-1.51.5
Food consumed during 24 hour testing period1.31.52.50.3-0.2-0.5-1.5-1.3-1.61.51.51.51.51.51.5-1.51.21.51.51.1-0.20.5-0.5
Glucose0.81.22.3-0.00.6-1.4-1.1-1.2-0.91.01.11.01.11.01.0-0.91.21.01.01.41.5-1.31.3
Heart weight1.01.410.7-3.32.7-2.40.3-0.9-0.2-0.4-0.2-0.4-0.4-0.4-0.40.4-0.50.50.50.0-0.60.7-0.7
Delay discount hyperbolic model param0.60.74.5-1.62.1-1.90.1-0.2-0.00.60.40.60.40.50.5-0.40.50.60.60.40.3-0.20.2
Intermittent access intake day 1-15 change2.62.64.50.9-0.2-0.2-1.9-2.0-1.51.91.91.91.91.91.9-1.82.11.61.61.81.0-0.90.9
Intermittent access intake escalation3.13.15.80.00.7-0.7-2.0-2.2-1.72.12.02.12.12.12.1-2.12.41.91.91.80.7-0.60.6
Intermittent access intake escalation 25.85.812.00.8-0.2-0.3-3.2-3.3-2.62.72.72.82.72.82.8-2.83.52.52.52.50.9-0.80.8
Intermitt. access day 1 inactive lever presses2.32.512.0-3.52.6-1.21.41.30.7-1.5-1.7-1.5-1.8-1.5-1.51.5-1.4-0.6-0.6-1.2-1.21.0-1.0
Intermitt. access day 15 inactive lever presses1.01.18.0-2.62.8-2.4-0.1-0.0-0.40.0-0.00.1-0.00.10.10.20.00.60.60.90.4-0.40.4
Intermitt. access escalation Index0.60.51.51.2-0.90.81.00.90.9-0.4-0.4-0.5-0.4-0.4-0.40.6-0.8-0.9-0.9-0.60.5-0.50.5
Intermittent access day 1 total infusions1.31.52.7-1.21.2-0.81.51.71.3-1.4-1.4-1.4-1.3-1.3-1.31.4-1.4-1.2-1.2-0.90.0-0.30.3
Intermittent access day 15 total infusions0.30.31.8-1.01.3-1.1-0.1-0.1-0.10.20.20.20.20.30.3-0.10.40.30.30.60.5-0.60.6
Intermittent access terminal intake (last 3 days)0.60.71.4-0.20.8-0.8-0.8-0.9-0.60.90.90.90.91.01.0-0.81.20.80.81.00.7-0.70.7
Intermittent access total infusions0.50.54.0-2.01.8-1.20.40.30.2-0.4-0.4-0.4-0.4-0.4-0.40.4-0.1-0.0-0.0-0.1-0.20.1-0.1
Intermittent access day 1 locomotion3.43.66.0-1.40.8-0.32.12.41.7-2.4-2.4-2.4-2.4-2.3-2.32.4-2.5-1.9-1.9-1.5-0.40.2-0.2
Intermittent access day 15 total locomotion1.11.29.4-3.12.9-2.0-0.1-0.3-0.40.20.10.20.10.20.2-0.20.40.80.80.2-0.70.5-0.5
Intermittent access total locomotion1.11.39.1-3.02.4-1.40.60.60.3-0.9-0.9-0.9-0.9-0.9-0.90.7-0.5-0.1-0.1-0.6-0.80.7-0.7
Intermittent access standard deviation1.21.22.1-0.50.8-0.8-1.2-1.4-1.21.31.21.31.21.31.3-1.21.41.31.31.20.0-0.10.1
Left kidney weight0.41.28.3-2.92.1-1.7-0.0-0.6-0.4-0.9-1.0-0.8-1.0-1.0-1.01.1-0.80.20.20.50.0-0.00.0
Right kidney weight0.61.78.8-3.01.7-1.50.2-0.4-0.3-1.5-1.5-1.4-1.5-1.5-1.51.6-1.7-0.1-0.10.1-0.80.9-0.9
Cocaine induced anxiety2.32.718.0-4.23.5-3.5-0.50.1-1.0-0.5-0.4-0.6-0.5-0.6-0.60.5-0.70.80.81.1-1.01.2-1.2
Post-drug Anxiety0.91.03.5-1.41.2-1.9-1.2-0.9-1.40.70.80.70.50.70.7-0.60.41.21.21.4-0.50.5-0.5
Baseline Anxiety0.91.06.52.5-1.90.9-0.4-0.5-0.10.90.90.90.91.01.0-0.80.80.10.10.40.6-0.90.9
Tail length0.61.93.6-1.71.9-1.8-1.2-1.5-1.61.31.31.41.41.41.4-1.21.11.61.61.5-0.1-0.20.2
Length with tail0.31.18.6-2.92.4-2.00.2-0.4-0.3-0.4-0.3-0.4-0.3-0.3-0.30.3-0.70.40.4-0.0-1.10.8-0.8
Length without tail1.22.64.7-0.4-0.20.72.01.21.9-2.0-1.7-2.0-1.9-2.0-2.01.7-2.1-1.7-1.7-2.2-0.90.8-0.8
Times rat made contact with spout0.50.61.21.1-1.00.30.50.70.6-0.6-0.7-0.6-0.7-0.6-0.60.8-0.5-0.8-0.80.01.0-1.01.0
Lifetime Intake0.20.20.6-0.80.6-0.20.50.40.4-0.4-0.5-0.5-0.4-0.4-0.40.4-0.4-0.3-0.3-0.4-0.30.2-0.2
Liver weight, left0.71.23.6-0.90.10.6-0.6-1.8-0.80.70.80.70.80.70.7-1.10.90.80.8-0.8-1.91.9-1.9
Liver weight, right0.20.40.9-0.5-0.20.20.2-0.30.0-0.7-0.8-0.7-0.7-0.6-0.60.7-1.0-0.3-0.3-0.4-0.90.9-0.9
Locomotor activity0.10.10.50.3-0.40.40.10.2-0.0-0.0-0.10.1-0.1-0.0-0.00.1-0.20.20.2-0.1-0.70.5-0.5
Locomotor testing distance0.10.10.70.8-0.60.20.10.50.2-0.1-0.2-0.1-0.1-0.2-0.20.3-0.2-0.2-0.20.30.2-0.40.4
Locomotor testing rearing0.20.31.4-0.91.2-1.2-0.20.3-0.20.30.30.40.30.20.2-0.20.30.50.50.50.1-0.20.2
Locomotion in novel chamber0.60.72.71.6-1.20.40.60.90.7-0.5-0.5-0.7-0.5-0.5-0.50.8-1.0-1.0-1.00.11.0-1.11.1
Locomotion in novel chamber post-restriction0.91.14.30.0-0.60.8-0.4-1.1-0.60.80.90.70.90.80.8-1.10.60.70.7-0.7-2.02.1-2.1
Fecal boli incidents, locomotor time 10.80.97.32.7-2.51.2-0.5-0.3-0.30.50.50.30.50.50.5-0.30.1-0.2-0.20.50.5-0.20.2
Change in fecal boli incidents, locomotor task0.60.55.0-2.21.9-1.1-0.1-0.2-0.3-0.10.0-0.10.0-0.0-0.0-0.10.30.40.4-0.0-0.40.2-0.2
Time >=10cm from walls, locomotor time 10.70.71.41.2-0.60.0-0.8-0.8-0.81.01.20.91.21.01.0-1.10.80.60.60.60.5-0.20.2
Bouts of movement, locomotor time 10.80.96.72.6-2.31.5-0.4-0.5-0.20.70.40.70.40.60.6-0.40.30.10.10.40.6-0.20.2
Total resting periods, locomotor time 10.50.53.71.9-1.50.8-0.4-0.4-0.20.70.50.70.50.70.7-0.40.30.20.20.50.6-0.10.1
Rest time, locomotor task time 10.10.10.7-0.50.3-0.3-0.1-0.2-0.30.30.20.30.20.30.3-0.2-0.00.30.30.0-0.60.8-0.8
Distance moved, locomotor task time 11.01.12.11.4-0.90.51.11.31.3-0.9-0.9-0.9-0.9-0.9-0.91.0-1.0-1.2-1.2-0.41.2-1.21.2
Vertical activity count, locomotor time 10.10.10.50.7-0.50.40.40.20.3-0.00.20.20.20.00.0-0.1-0.4-0.1-0.1-0.4-0.1-0.10.1
Time >=10cm from walls, locomotor time 21.41.57.5-2.72.0-1.01.11.00.5-1.2-0.9-1.4-0.9-1.1-1.11.0-1.1-0.7-0.7-1.1-1.10.9-0.9
Bouts of movement, locomotor time 21.31.44.61.4-1.22.11.31.21.7-0.9-0.9-0.9-0.9-0.8-0.80.7-0.2-1.5-1.5-1.50.6-0.90.9
Total resting periods, locomotor time 21.21.34.81.5-1.32.21.21.11.6-0.8-0.8-0.8-0.8-0.7-0.70.6-0.2-1.4-1.4-1.50.5-0.90.9
Rest time, locomotor task time 21.61.93.00.3-0.0-0.7-1.6-1.7-1.61.71.71.71.71.71.7-1.61.31.51.51.4-0.30.4-0.4
Distance moved, locomotor task time 21.41.63.8-0.60.5-0.41.61.81.3-1.5-1.6-1.4-1.6-1.6-1.61.7-1.9-1.1-1.1-0.70.1-0.30.3
Vertical activity count, locomotor time 20.90.92.4-0.40.6-0.21.51.61.3-1.0-0.9-0.9-0.9-1.0-1.01.1-1.5-0.9-0.9-1.1-0.10.2-0.2
Light reinforcement 12.85.012.1-1.21.5-1.63.22.92.5-2.5-2.5-2.4-2.5-2.4-2.43.1-3.5-2.1-2.1-1.00.6-0.40.4
Light reinforcement 20.20.21.3-0.71.1-1.20.60.90.2-0.2-0.2-0.2-0.1-0.1-0.10.4-0.6-0.0-0.00.40.2-0.10.1
Bone: marrow area0.10.10.30.1-0.00.2-0.3-0.5-0.20.50.40.40.40.50.5-0.50.50.30.30.10.1-0.20.2
Bone: maximum diameter0.10.20.50.6-0.40.40.6-0.10.7-0.2-0.2-0.2-0.3-0.2-0.20.3-0.5-0.4-0.4-0.40.4-0.30.3
Bone: maximum force0.20.33.0-0.50.7-1.70.1-0.3-0.0-0.1-0.1-0.1-0.1-0.1-0.10.4-0.70.00.00.70.9-0.70.7
Bone: maximum moment0.20.32.4-0.40.6-1.60.1-0.3-0.1-0.0-0.1-0.0-0.0-0.0-0.00.4-0.60.00.00.81.0-0.80.8
Mean time between licks in bursts0.40.51.20.3-0.50.1-1.1-0.7-1.00.80.60.80.70.80.8-0.81.00.80.80.7-0.30.2-0.2
Mean num. licks in bursts1.51.73.1-1.81.4-1.01.41.51.1-1.6-1.6-1.6-1.5-1.6-1.61.7-1.6-1.1-1.1-0.6-0.20.2-0.2
Cd content in liver0.20.21.51.2-1.20.6-0.2-0.4-0.10.20.10.20.10.20.2-0.10.1-0.1-0.10.0-0.10.0-0.0
Co content in liver0.91.03.01.7-1.50.2-1.3-1.0-1.11.00.81.00.81.01.0-0.70.70.80.81.50.9-0.70.7
Cu content in liver1.82.23.60.7-0.3-0.1-1.7-1.7-1.61.91.81.91.81.91.9-1.81.91.71.71.30.1-0.10.1
Fe content in liver0.30.41.8-0.20.7-0.31.11.31.1-0.3-0.4-0.3-0.4-0.3-0.30.30.1-0.6-0.6-0.90.0-0.30.3
K content in liver1.61.63.50.6-0.7-0.1-1.4-1.9-1.61.51.31.51.31.51.5-1.40.91.51.51.1-0.90.6-0.6
Mg content in liver3.33.46.61.5-1.1-0.2-2.2-2.6-2.02.22.22.22.22.22.2-2.01.81.91.91.90.7-0.80.8
Mn content in liver0.20.31.30.0-0.0-0.9-0.6-0.7-0.80.40.10.40.10.40.40.0-0.30.60.61.1-0.0-0.10.1
Na content in liver1.41.57.1-2.72.0-0.7-0.4-0.3-0.70.40.40.40.40.40.4-0.80.80.90.9-0.8-2.02.1-2.1
Rb content in liver1.41.73.61.5-1.3-0.5-1.6-1.9-1.31.11.11.11.11.11.1-0.91.30.80.81.81.8-1.61.6
Se content in liver0.60.71.70.7-0.2-0.5-0.7-0.8-0.60.80.60.80.60.80.8-0.50.60.70.71.31.1-1.31.3
Sr content in liver0.30.21.20.1-0.60.5-0.10.0-0.3-0.2-0.2-0.2-0.2-0.2-0.20.1-0.50.00.0-0.2-1.11.1-1.1
Zn content in liver2.62.94.5-0.90.7-1.3-1.6-1.7-2.01.81.81.81.81.81.8-1.91.52.12.11.0-1.81.8-1.8
Bone: minimum diameter0.20.41.91.0-1.40.80.2-0.00.2-0.6-0.7-0.6-0.7-0.6-0.60.8-0.9-0.7-0.7-0.00.3-0.10.1
Time in familiar zone, hab. session 11.11.02.11.0-1.21.4-1.0-0.8-0.81.01.01.01.11.01.0-1.31.40.70.7-0.1-0.70.8-0.8
Time in novel zone, hab. session 11.11.12.2-0.61.1-1.31.10.81.0-1.0-1.0-1.0-1.0-1.0-1.01.3-1.1-0.9-0.90.21.3-1.51.5
Total zone transitions, hab. session 10.71.04.6-0.8-0.00.1-0.6-0.6-1.00.50.50.50.50.50.5-0.70.10.90.9-0.1-2.12.1-2.1
Total locomotion distance, hab. session 10.81.15.3-1.00.3-0.6-0.8-0.8-1.30.60.60.60.50.60.6-0.6-0.01.11.10.4-2.31.9-1.9
Locomotion velocity, hab. session 10.81.17.0-1.20.3-0.4-0.5-0.3-1.00.10.20.10.10.10.1-0.3-0.50.80.8-0.0-2.62.3-2.3
Time in familiar zone, hab. session 20.50.54.12.0-1.71.30.0-0.20.20.50.50.50.50.50.5-0.40.2-0.2-0.2-0.20.2-0.00.0
Time in novel zone, hab. session 20.70.72.6-1.61.6-1.50.20.40.1-0.7-0.7-0.7-0.7-0.7-0.70.8-0.5-0.2-0.20.40.5-0.70.7
Total zone transitions, hab. session 21.41.93.8-0.5-0.0-0.5-1.7-1.5-2.01.31.41.31.31.31.3-1.41.01.71.71.0-1.61.5-1.5
Total locomotion distance, hab. session 20.70.92.3-1.51.1-1.0-0.9-0.9-1.30.60.70.60.70.60.6-0.70.51.21.20.6-1.31.2-1.2
Locomotion velocity, hab. session 20.60.82.5-1.50.9-0.6-0.7-0.6-1.10.40.40.40.40.40.4-0.50.31.01.00.3-1.61.5-1.5
Novel to familiar place preference ratio1.51.52.4-1.31.0-0.31.51.11.4-1.5-1.6-1.5-1.5-1.5-1.51.6-1.1-1.3-1.3-1.1-0.20.3-0.3
Novelty place preference1.51.52.5-1.31.0-0.41.51.11.3-1.6-1.6-1.6-1.6-1.6-1.61.6-1.2-1.2-1.2-1.0-0.10.2-0.2
Time in novel zone, NPP test1.31.32.2-1.31.0-0.51.41.11.3-1.4-1.4-1.4-1.4-1.4-1.41.5-1.0-1.2-1.2-0.9-0.10.1-0.1
Total zone transitions, NPP test2.02.96.5-0.2-0.2-0.5-2.4-1.9-2.51.91.91.91.91.91.9-2.01.62.22.21.7-1.00.8-0.8
Total locomotion distance, NPP test1.42.05.6-1.20.7-1.1-2.1-1.5-2.41.21.21.21.31.21.2-1.21.01.91.91.7-1.00.7-0.7
Locomotion velocity, NPP test1.21.75.2-1.10.5-0.9-2.0-1.4-2.31.11.11.11.11.11.1-1.10.91.81.81.6-1.00.7-0.7
Intraocular pressure2.13.015.33.9-3.12.21.11.91.6-0.8-0.9-0.9-0.8-0.8-0.81.1-1.2-1.8-1.8-0.41.6-1.81.8
Delta distance traveled before/after self-admin0.30.41.2-0.00.01.00.60.60.9-0.6-0.5-0.6-0.5-0.5-0.50.30.2-0.8-0.8-1.10.1-0.10.1
Delta ambulatory time before/after self-admin0.70.81.5-1.10.90.21.11.01.1-1.0-1.0-1.1-1.0-0.9-0.90.8-0.4-1.0-1.0-1.2-0.10.1-0.1
Parametrial fat weight0.81.64.4-1.90.8-0.10.80.60.5-1.2-1.1-1.2-1.1-1.1-1.10.8-1.2-0.6-0.6-1.4-2.12.1-2.1
Pavlov. Cond. lever latency0.81.05.82.4-1.71.2-0.2-0.50.20.70.60.70.70.70.7-0.50.7-0.1-0.10.41.6-1.31.3
Pavlov. Cond. magazine entry latency2.43.013.4-3.73.5-2.81.61.50.9-1.5-1.4-1.5-1.5-1.5-1.51.6-1.8-0.5-0.5-0.5-1.00.7-0.7
Pavlov. Cond. change in total contacts2.12.212.8-3.63.3-3.2-0.6-0.6-1.20.50.50.50.40.50.5-0.40.31.41.40.9-1.00.8-0.8
Pavlov. Cond. index score1.11.37.1-2.72.2-1.80.70.90.2-0.9-0.8-0.9-0.8-0.9-0.90.8-1.0-0.1-0.1-0.4-1.41.1-1.1
Pavlov. Cond. latency score1.31.67.3-2.72.0-1.50.81.00.3-1.1-1.0-1.1-1.1-1.1-1.11.0-1.2-0.3-0.3-0.6-1.71.4-1.4
Pavlov. Cond. lever contacts0.91.16.6-2.61.8-1.30.10.4-0.3-0.6-0.5-0.6-0.6-0.6-0.60.4-0.70.20.2-0.3-1.71.5-1.5
Pavlov. Cond. magazine entry number1.51.98.93.0-2.92.6-1.1-1.1-0.61.11.01.11.11.11.1-1.21.30.30.30.10.6-0.30.3
Pavlov. Cond. intertrial magazine entries1.51.810.93.3-2.42.0-0.4-0.70.11.21.21.21.31.21.2-1.11.00.10.10.01.2-1.01.0
Pavlov. Cond. lever-magazine prob. diff.0.81.06.2-2.52.1-1.90.30.6-0.2-0.5-0.5-0.5-0.5-0.5-0.50.5-0.60.20.2-0.0-1.30.9-0.9
Pavlov. Cond. response bias1.11.49.4-3.13.0-2.60.20.4-0.3-0.2-0.2-0.2-0.2-0.2-0.20.3-0.40.60.60.4-0.80.5-0.5
Pavlov. Cond. lever latency2.73.76.91.4-1.30.6-2.6-1.8-2.62.32.32.22.32.32.3-2.31.92.02.02.0-0.30.1-0.1
Pavlov. Cond. magazine entry latency2.02.35.4-1.92.3-1.62.11.72.0-1.5-1.5-1.5-1.6-1.5-1.51.6-1.3-1.3-1.3-1.20.5-0.40.4
Pavlov. Cond. change in total contacts1.82.510.4-3.23.1-1.91.81.21.5-1.3-1.3-1.3-1.3-1.3-1.31.2-1.0-0.8-0.8-1.6-0.70.9-0.9
Pavlov. Cond. index score2.22.86.4-2.22.5-1.52.41.72.3-1.7-1.7-1.7-1.8-1.7-1.71.7-1.4-1.5-1.5-1.60.3-0.30.3
Pavlov. Cond. latency score1.72.26.3-2.12.5-1.62.01.41.9-1.4-1.4-1.4-1.5-1.4-1.41.4-1.1-1.2-1.2-1.30.4-0.40.4
Pavlov. Cond. lever contacts3.95.310.1-1.31.1-0.13.22.43.2-2.7-2.7-2.7-2.7-2.7-2.72.6-2.3-2.6-2.6-2.8-0.20.4-0.4
Pavlov. Cond. magazine entry number1.72.08.52.5-2.91.8-1.8-1.2-1.71.21.21.21.31.21.2-1.30.90.90.91.0-0.40.5-0.5
Pavlov. Cond. intertrial magazine entries0.81.07.32.5-2.71.6-0.9-0.5-0.50.30.40.40.40.30.3-0.30.4-0.0-0.00.50.6-0.50.5
Pavlov. Cond. lever-magazine prob. diff.2.12.76.5-2.22.5-1.62.31.62.2-1.6-1.6-1.6-1.7-1.6-1.61.6-1.3-1.4-1.4-1.60.3-0.30.3
Pavlov. Cond. response bias3.64.810.4-1.91.9-0.73.22.33.1-2.4-2.5-2.4-2.5-2.4-2.42.4-2.1-2.3-2.3-2.6-0.00.2-0.2
Time in closed arm before self-admin1.11.24.92.2-2.12.11.11.01.2-0.6-0.6-0.6-0.6-0.5-0.50.6-0.7-1.3-1.3-1.10.1-0.20.2
Time in closed arm after self-admin0.50.51.60.30.2-0.11.31.31.2-0.5-0.6-0.5-0.6-0.5-0.50.8-0.9-0.9-0.9-0.50.6-0.50.5
Time in open arm before self-admin1.11.22.51.1-1.21.60.91.01.3-1.2-1.1-1.2-1.0-1.1-1.10.9-0.7-1.3-1.3-1.00.9-0.70.7
Time in open arm after self-admin0.70.82.9-0.20.6-0.2-1.2-1.0-0.70.70.80.80.80.70.7-1.01.70.90.90.81.0-1.01.0
Bone: periosteal estimation0.10.20.80.9-0.60.1-0.1-0.50.00.30.30.30.20.30.3-0.10.0-0.0-0.00.30.8-0.70.7
Bone: periosteal perimeter0.10.21.01.0-0.80.10.1-0.20.1-0.1-0.1-0.2-0.2-0.1-0.10.4-0.6-0.3-0.30.30.6-0.60.6
Bone: post-yield work0.81.14.5-2.11.4-1.1-1.1-0.9-1.40.50.60.50.60.50.5-0.80.61.21.20.5-1.21.3-1.3
Progressive ratio test 1 active lever presses0.70.74.5-1.92.1-1.60.80.80.4-0.4-0.3-0.4-0.3-0.4-0.40.6-0.8-0.1-0.1-0.1-0.1-0.30.3
Progressive ratio test 1 breakpoint0.70.75.1-2.12.3-1.80.30.4-0.0-0.00.0-0.10.1-0.0-0.00.1-0.40.30.30.2-0.3-0.10.1
Progressive ratio test 1 inactive lever presses1.21.38.0-2.72.8-1.80.90.90.7-0.8-0.9-0.8-0.9-0.8-0.80.9-0.5-0.3-0.3-0.10.3-0.50.5
Progressive ratio test 2 active lever presses1.01.18.5-2.82.9-2.30.40.40.1-0.2-0.1-0.2-0.1-0.1-0.10.2-0.10.20.20.1-0.10.0-0.0
Progressive ratio test 2 breakpoint1.01.17.5-2.42.7-2.20.80.90.6-0.5-0.4-0.5-0.3-0.4-0.40.5-0.5-0.2-0.2-0.10.2-0.30.3
Progressive ratio test 2 inactive lever presses0.80.96.1-2.12.5-2.10.30.40.0-0.2-0.2-0.2-0.2-0.1-0.10.3-0.10.20.20.60.5-0.70.7
Incentive Sensitization - Responses0.20.20.8-0.30.7-0.9-0.3-0.1-0.10.30.40.30.40.40.4-0.30.40.20.20.60.7-0.60.6
Incentive Sensitization - Breakpoint0.20.21.1-0.51.0-1.0-0.10.0-0.00.10.30.10.20.20.2-0.10.30.10.10.50.7-0.60.6
Sum of active levers in priming session hrs 5-61.31.22.20.4-0.1-0.5-1.3-1.5-1.21.41.31.41.41.31.3-1.31.41.21.21.20.2-0.20.2
Progressive ratio0.70.83.7-0.7-0.10.9-0.0-0.5-0.10.00.10.20.10.20.2-0.50.50.30.3-1.3-1.91.9-1.9
Food seeking constrained by brief footshock0.30.40.9-0.90.6-0.10.60.60.7-0.8-0.7-0.8-0.7-0.9-0.90.8-0.6-0.5-0.5-0.6-0.3-0.10.1
Seeking ratio, punishment vs. effort0.91.13.70.50.1-0.50.71.10.9-0.7-0.7-0.8-0.7-0.8-0.81.1-0.9-0.9-0.90.61.8-1.91.9
Retroperitoneal fat weight0.51.64.0-2.01.6-1.31.80.31.3-1.2-1.2-1.2-1.2-1.1-1.11.4-1.8-1.0-1.0-1.3-0.50.6-0.6
Reaction time number correct0.91.34.2-0.20.5-1.0-1.1-2.1-1.01.31.31.31.41.21.2-1.21.11.21.21.00.5-0.50.5
Reaction time mean minus median0.30.40.90.3-0.50.70.70.20.7-0.6-0.5-0.6-0.7-0.6-0.60.5-0.7-0.6-0.6-0.9-0.60.6-0.6
Reaction time mean minus median AUC0.40.61.2-0.30.2-0.20.80.30.8-1.0-0.7-1.0-1.0-1.0-1.00.9-1.1-0.8-0.8-0.7-0.10.1-0.1
Reaction time num false alarms0.40.53.5-1.51.7-1.9-0.3-0.0-0.60.10.30.10.10.20.2-0.0-0.10.60.60.90.1-0.10.1
Reaction time num false alarms AUC0.20.32.4-1.31.6-1.30.10.3-0.1-0.10.1-0.1-0.10.00.00.1-0.10.20.20.30.2-0.20.2
Reaction time trials correct on left0.91.34.2-0.20.5-1.0-1.1-2.1-1.01.31.31.31.41.21.2-1.21.11.21.21.00.5-0.50.5
Reaction time trials on left0.91.24.0-0.30.6-1.0-1.1-2.0-1.01.21.31.21.41.21.2-1.21.11.21.21.00.6-0.60.6
Reaction time mean0.30.42.81.7-1.01.30.70.40.90.20.30.20.00.10.1-0.20.0-0.5-0.5-0.80.1-0.00.0
Reaction time mean AUC0.40.53.21.8-1.21.30.70.40.90.00.10.1-0.1-0.0-0.0-0.1-0.1-0.6-0.6-0.80.2-0.20.2
Median of all reaction times0.30.43.41.8-1.01.20.60.50.80.40.40.40.20.30.3-0.40.3-0.4-0.4-0.60.3-0.20.2
Reaction time omissions0.71.01.6-1.11.0-0.41.11.11.0-1.2-1.3-1.3-1.3-1.3-1.31.3-1.1-0.9-0.9-0.7-0.00.3-0.3
Reaction time false alarm rate0.30.41.5-0.90.9-0.60.61.20.4-0.7-0.6-0.7-0.8-0.6-0.60.7-0.7-0.4-0.4-0.2-0.10.2-0.2
Reaction time premature initiation rate1.01.34.5-2.11.9-1.41.21.20.6-0.7-0.7-0.8-0.6-0.7-0.70.7-1.4-0.3-0.3-0.8-1.31.4-1.4
Reaction time premature initiations0.60.95.0-2.22.2-1.90.50.10.1-0.1-0.0-0.10.1-0.1-0.10.1-0.70.40.4-0.2-0.80.9-0.9
Std. dev. reaction times0.91.22.21.5-1.31.31.40.81.4-1.0-0.9-1.0-1.1-1.0-1.01.0-1.1-1.4-1.4-1.30.1-0.00.0
Reaction time trials completed0.91.24.0-0.30.6-1.0-1.1-2.0-1.01.21.31.21.41.21.2-1.21.11.21.21.00.6-0.60.6
Reaction time trials AUC0.91.33.9-0.30.7-1.1-1.0-2.0-0.91.31.41.31.41.21.2-1.21.21.21.20.90.6-0.50.5
Run reversals in cocaine runway, females2.62.54.2-0.40.7-1.0-1.9-2.0-1.91.91.91.81.91.91.9-1.92.01.81.81.5-0.10.1-0.1
Run reversals in cocaine runway, males0.20.20.90.10.2-0.5-0.4-0.3-0.30.30.30.30.30.30.3-0.20.60.20.20.81.0-0.70.7
Latency to leave start box in cocaine runway0.60.62.0-1.41.1-0.11.00.70.8-0.7-0.7-0.8-0.7-0.6-0.60.5-0.4-0.6-0.6-1.2-0.90.8-0.8
Latency to leave start box in cocaine runway, F0.60.71.5-0.2-0.51.00.60.50.5-0.9-0.9-1.0-0.9-0.7-0.70.5-0.6-0.8-0.8-1.2-1.11.1-1.1
Latency to leave start box in cocaine runway, M1.21.19.7-2.83.1-1.90.90.70.5-0.1-0.2-0.1-0.2-0.1-0.10.10.00.20.2-0.3-0.20.2-0.2
Std. dev. time between licks in bursts0.40.51.00.7-1.00.80.50.10.6-0.8-0.9-0.8-1.0-0.8-0.80.9-0.7-0.8-0.8-0.40.2-0.10.1
Total sessions with >9 infusions1.51.73.40.0-0.70.61.21.41.0-1.6-1.7-1.7-1.7-1.6-1.61.7-1.8-1.4-1.4-1.0-0.50.6-0.6
Short access day 1 total inactive lever presses0.00.10.20.4-0.40.50.30.10.2-0.1-0.1-0.1-0.2-0.0-0.00.1-0.2-0.2-0.2-0.3-0.20.2-0.2
Short access day 10 total inactive lever presses4.75.333.5-5.85.2-4.3-0.9-1.0-1.80.60.40.60.40.60.6-0.50.62.02.01.4-1.51.7-1.7
Short access day 1 total infusions0.40.52.01.0-1.21.40.60.50.6-0.5-0.6-0.6-0.5-0.5-0.50.5-0.6-0.7-0.7-0.7-0.20.3-0.3
Short access day 10 total infusions1.01.12.0-1.20.7-0.31.21.10.9-1.2-1.1-1.2-1.0-1.2-1.21.0-1.4-0.8-0.8-1.2-1.21.0-1.0
Short access total infusions0.50.61.51.1-1.21.20.80.70.8-0.6-0.5-0.7-0.5-0.6-0.60.6-0.9-0.8-0.8-0.9-0.40.4-0.4
Short access day 1 locomotion0.91.01.7-0.2-0.10.41.21.31.2-1.2-1.0-1.2-0.9-1.1-1.11.0-1.3-1.2-1.2-1.3-0.50.4-0.4
Short access day 10 total locomotion0.40.41.60.7-1.31.0-1.0-0.9-1.00.40.20.40.20.30.3-0.40.40.50.50.4-0.40.3-0.3
Short access total locomotion1.81.94.2-1.00.20.11.41.50.9-1.7-1.6-1.8-1.6-1.7-1.71.6-2.0-1.2-1.2-1.3-1.21.0-1.0
One hour access (0.3 mA shock)2.93.44.8-1.22.1-2.0-1.7-1.9-1.62.12.12.12.02.22.2-1.92.12.02.02.00.6-0.70.7
Compulsive drug intake1.01.03.81.9-1.31.5-0.4-0.7-0.11.21.01.10.91.11.1-1.11.20.30.30.20.8-0.80.8
One hour access (shock baseline)1.11.39.1-3.02.9-2.70.20.3-0.1-0.4-0.3-0.4-0.3-0.4-0.40.4-0.30.30.30.4-0.40.2-0.2
Social response proportion2.42.618.9-4.34.3-2.51.30.60.9-0.7-0.7-0.6-0.7-0.7-0.70.5-0.40.00.0-1.1-1.00.6-0.6
Social responses0.70.93.3-0.81.8-1.21.61.41.5-0.6-0.5-0.5-0.4-0.5-0.50.7-0.9-0.7-0.7-0.60.8-1.01.0
Social time0.30.41.91.0-0.61.41.00.41.0-0.0-0.30.0-0.2-0.1-0.10.2-0.5-0.5-0.5-1.0-0.2-0.10.1
Soleus weight0.10.20.70.8-0.20.50.3-0.30.20.70.40.70.60.70.7-0.30.20.20.20.10.6-0.40.4
Bone: stiffness0.40.64.4-1.41.4-2.1-0.3-0.8-0.60.30.30.40.30.30.3-0.1-0.30.80.80.7-0.10.3-0.3
Tibialis anterior weight0.10.40.90.10.7-0.00.4-0.60.20.90.71.00.70.90.9-0.50.30.50.50.20.5-0.30.3
Time to tail flick, vehicle, before self-admin0.80.83.7-0.5-0.60.90.20.0-0.1-0.7-0.6-0.6-0.6-0.6-0.60.3-0.6-0.3-0.3-1.1-1.71.9-1.9
Time to tail flick, vehicle, after self-admin0.70.74.82.2-1.61.0-0.5-0.4-0.30.70.90.70.80.70.7-0.60.40.20.20.50.9-0.60.6
Time to tail flick, test, before self-admin0.40.41.4-0.90.6-0.80.50.50.1-0.2-0.4-0.3-0.4-0.4-0.40.5-1.2-0.0-0.0-0.1-0.91.0-1.0
Time to tail flick, test, after self-admin0.50.62.2-0.70.21.00.70.50.8-0.8-0.8-0.7-0.8-0.8-0.80.4-0.1-0.5-0.5-1.5-0.80.6-0.6
Delta time to tail flick, vehicle, before/after SA1.11.12.40.70.4-0.9-0.7-0.5-0.51.11.21.01.11.11.1-0.81.00.70.71.41.5-1.61.6
Delta time to tail flick, test, before/after SA1.41.34.90.8-1.12.21.00.91.4-1.3-1.1-1.1-1.1-1.2-1.20.8-0.2-1.3-1.3-1.80.1-0.40.4
Tibia length0.72.16.1-2.01.3-1.71.01.00.5-1.7-1.7-1.7-1.8-1.7-1.71.8-2.5-0.8-0.8-0.3-0.90.8-0.8
Ambulatory time before self-admin0.10.10.50.4-0.60.30.30.30.2-0.1-0.2-0.1-0.2-0.4-0.40.3-0.7-0.1-0.1-0.4-0.50.3-0.3
Ambulatory time after self-admin0.10.10.50.30.10.2-0.1-0.10.10.50.50.50.50.40.4-0.50.70.10.1-0.20.3-0.40.4
Bone: tissue strength0.40.43.2-1.81.4-1.1-0.3-0.3-0.5-0.1-0.1-0.2-0.1-0.1-0.10.2-0.10.40.40.5-0.30.2-0.2
Total heroin consumption0.81.02.20.9-0.9-0.2-1.5-1.4-1.41.11.21.11.10.90.9-1.00.71.01.01.40.10.1-0.1
Bone: trabecular number1.01.53.9-1.21.1-1.2-1.3-2.0-1.41.31.41.31.21.31.3-1.31.21.51.50.7-0.40.5-0.5
Bone: trabecular spacing3.54.68.31.9-1.71.62.42.92.6-2.3-2.5-2.3-2.3-2.3-2.32.4-2.3-2.7-2.7-1.50.9-0.90.9
Bone: trabecular thickness1.31.53.20.9-0.50.4-1.1-1.3-1.01.71.81.61.71.71.7-1.71.41.21.20.5-0.10.2-0.2
Bone: trabecular tissue density5.78.012.8-0.70.9-1.6-3.5-3.0-3.63.33.53.33.33.33.3-3.53.23.53.52.6-0.50.7-0.7
Water consumed over 24 hours0.20.20.91.0-0.4-0.20.20.50.40.00.20.00.10.00.0-0.0-0.1-0.3-0.30.11.0-0.80.8
Number of responses in last shaping day1.41.54.22.1-1.71.51.21.41.2-1.0-0.9-1.1-0.9-0.8-0.81.2-1.4-1.5-1.5-0.60.9-0.80.8