Hub : Genes

Cat

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Cat 0.1 0.1 1.2e-09 0.07 0.06 0.06 0.06 2.1e-10 3.0e-09 7.0e-10 4.8e-10
2 OFC gene expression Cat 0.17 0.15 2.1e-03 0.09 0.09 0.09 0.09 3.2e-03 3.5e-03 3.9e-03 3.4e-03
3 PL gene expression Cat 0.11 0.08 4.0e-10 0.09 0.09 0.09 0.08 4.4e-10 1.1e-09 1.4e-09 2.1e-09
4 Brain mRNA stability Cat 0.07 0.05 7.4e-08 0.08 0.06 0.07 0.03 1.0e-07 1.5e-06 2.5e-07 2.0e-03
5 BLA gene expression Cat 0.18 0.15 6.8e-07 0.1 0.12 0.09 0.1 4.0e-06 1.1e-06 2.5e-05 4.1e-06
6 Liver gene expression Cat 0.05 0.04 9.4e-06 0.03 0.03 0.03 0.03 1.4e-04 2.2e-04 1.5e-04 3.8e-04
7 LHb gene expression Cat 0.44 0.19 3.0e-10 0.32 0.32 0.2 0.26 1.9e-08 1.8e-08 1.6e-05 6.9e-07
8 IC mRNA stability Cat 0.07 0.06 6.6e-03 0.04 0.06 0.04 0.05 5.7e-03 2.5e-03 6.1e-03 5.3e-03
9 PL mRNA stability Cat 0.05 0.04 4.8e-06 0.04 0.04 0.04 0.04 9.5e-05 1.5e-05 9.0e-05 6.4e-05
10 NAcc gene expression Cat 0.1 0.06 0.0e+00 0.15 0.15 0.15 0.15 1.1e-21 2.0e-22 7.2e-22 4.5e-22
11 pVTA gene expression Cat 0.5 0.15 0.0e+00 0.56 0.59 0.59 0.58 3.6e-54 8.1e-59 4.4e-58 2.1e-57
12 Brain gene expression Cat 0.46 0.15 0.0e+00 0.52 0.52 0.52 0.52 1.3e-56 5.6e-56 9.0e-56 1.2e-56
13 IL mRNA stability Cat 0.16 0.19 9.7e-03 0.06 0.05 0.06 0.05 1.2e-02 2.8e-02 1.9e-02 2.8e-02
14 RMTg gene expression Cat 0.28 0.22 1.2e-04 0.11 0.15 0.14 0.14 9.2e-04 7.0e-05 1.6e-04 1.3e-04
15 pVTA mRNA stability Cat 0.09 0.09 9.2e-06 0.06 0.06 0.06 0.06 3.1e-05 1.3e-05 1.0e-05 1.0e-05
16 Liver mRNA stability Cat 0.11 0.09 9.6e-11 0.08 0.08 0.08 0.08 2.1e-09 3.5e-09 6.8e-09 3.6e-09
17 IC gene expression Cat 0.17 0.15 1.0e-04 0.08 0.07 0.06 0.07 2.8e-04 5.1e-04 1.6e-03 5.7e-04
18 Adipose gene expression Cat 0.3 0.21 0.0e+00 0.23 0.23 0.23 0.23 3.4e-25 3.3e-25 1.9e-25 1.7e-25
19 Adipose mRNA stability Cat 0.83 0.1 5.6e-16 0.11 0.14 0.12 0.12 1.3e-12 4.2e-15 2.8e-13 6.0e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.71.31.61.2-1.1-1.11.1-1.3-1.1-1.21.11.1-1.1-1.1-1.11.2-1.21.31.2-1.3-1.0-0.3
Area under the delay curve0.10.10.3-0.60.10.1-0.40.10.40.3-0.3-0.20.20.20.2-0.3-0.0-0.1-0.10.30.1-0.4
BMI with tail0.10.42.0-0.10.60.6-0.00.50.10.5-0.6-0.60.60.70.7-0.60.8-0.6-0.70.60.71.4
BMI without tail0.10.21.00.4-0.4-0.40.6-0.0-0.6-0.20.40.3-0.3-0.4-0.10.1-0.1-0.00.2-0.1-1.0-0.8
Body weight0.21.02.71.2-0.9-0.91.4-0.7-1.3-0.91.00.9-0.9-1.0-0.80.9-0.60.80.8-0.9-1.6-0.7
Weight adjusted by age2.23.34.2-1.71.71.7-1.81.71.81.8-1.9-1.81.81.81.9-2.01.7-1.9-1.82.02.01.6
Bone surface0.71.21.71.2-1.0-1.01.1-1.2-1.1-1.11.11.1-1.1-1.1-1.11.2-1.11.31.1-1.3-1.2-0.4
Bone volume1.62.83.61.9-1.6-1.61.8-1.8-1.8-1.81.71.7-1.7-1.6-1.71.8-1.71.91.7-1.9-1.4-0.5
Breakpoint value in progressive ratio session1.51.82.6-1.31.21.2-1.31.61.31.4-1.3-1.41.41.31.5-1.51.5-1.5-1.51.40.70.6
Number of licking bursts0.20.40.60.4-0.8-0.80.4-0.7-0.4-0.60.50.6-0.6-0.6-0.60.5-0.80.50.7-0.5-0.3-0.7
Context. condit. distance diff. score3.13.84.41.7-1.9-1.91.7-2.0-1.7-2.02.02.0-2.0-2.0-2.12.1-2.12.02.0-2.0-1.8-1.7
Locomotion velocity, session 10.10.10.3-0.20.40.4-0.20.30.20.2-0.3-0.20.30.30.20.00.2-0.1-0.20.10.60.5
Locomotion distance, session 10.00.10.50.10.10.10.2-0.1-0.2-0.10.00.0-0.00.0-0.10.3-0.10.20.0-0.20.40.7
Locomotion velocity, session 20.00.10.6-0.30.10.1-0.30.10.30.1-0.1-0.10.00.00.00.0-0.10.00.1-0.0-0.1-0.8
Locomotion distance, session 20.20.30.50.7-0.5-0.50.7-0.6-0.7-0.60.60.6-0.5-0.5-0.60.7-0.50.70.5-0.7-0.40.2
Locomotion velocity, session 30.10.10.20.2-0.1-0.10.3-0.4-0.3-0.30.20.2-0.2-0.2-0.30.3-0.30.40.3-0.40.10.4
Locomotion distance, session 30.20.20.30.4-0.3-0.30.5-0.5-0.5-0.40.40.4-0.4-0.4-0.40.5-0.40.50.5-0.50.00.0
Stereotopy head waving bouts, day 30.10.11.0-0.10.30.30.00.1-0.00.1-0.2-0.20.20.30.20.10.3-0.1-0.30.10.31.0
Stereotopy head waving duration, day 30.30.40.80.4-0.6-0.60.5-0.6-0.5-0.60.60.6-0.6-0.6-0.70.9-0.60.70.6-0.7-0.7-0.5
Locomotion velocity, session 70.00.00.30.30.00.00.2-0.1-0.2-0.20.20.1-0.1-0.1-0.10.10.00.10.0-0.1-0.10.6
Locomotion distance, session 70.40.51.2-0.40.80.8-0.50.70.50.6-0.6-0.60.60.70.7-0.70.8-0.7-0.80.70.71.1
Stereotopy head waving bouts, day 70.00.00.2-0.1-0.2-0.2-0.1-0.10.1-0.10.10.1-0.1-0.1-0.30.4-0.10.40.1-0.4-0.3-0.3
Stereotopy head waving duration, day 70.10.10.4-0.1-0.2-0.2-0.0-0.10.0-0.00.10.1-0.1-0.1-0.30.4-0.10.40.1-0.4-0.5-0.6
Locomotion velocity, session 80.40.50.80.8-0.6-0.60.8-0.6-0.8-0.80.80.8-0.8-0.7-0.70.8-0.60.90.6-0.9-0.5-0.1
Locomotion distance, session 83.04.45.32.0-2.0-2.02.1-2.1-2.1-2.22.22.2-2.2-2.1-2.22.3-2.12.22.0-2.2-1.9-1.2
Degree of sensitization distance0.30.30.6-0.50.60.6-0.60.70.60.6-0.5-0.50.50.50.6-0.70.5-0.8-0.60.80.20.1
Degree of sensitization stereotypy0.00.00.1-0.1-0.1-0.1-0.1-0.10.10.0-0.0-0.0-0.0-0.0-0.20.2-0.10.30.1-0.3-0.3-0.2
Conditioned locomotion3.64.15.1-2.32.12.1-2.12.02.12.1-2.1-2.12.12.12.0-1.91.9-2.0-2.02.02.11.4
Cocaine response after cond. corrected2.83.33.8-1.71.91.9-1.61.81.61.8-1.8-1.81.81.91.9-1.91.9-1.9-1.91.91.61.8
Cocaine response after cond. not corrected0.70.81.0-0.90.90.9-0.90.90.90.9-0.9-0.90.90.91.0-1.00.9-1.0-0.91.00.40.6
Cocaine response before conditioning5.97.09.62.3-2.8-2.82.2-2.6-2.2-2.52.62.6-2.7-2.7-2.72.6-2.92.62.8-2.5-2.9-3.1
Saline control response0.81.11.41.0-1.1-1.10.8-1.0-0.8-1.01.01.0-1.1-1.1-1.11.0-1.11.01.1-1.0-1.1-1.2
Bone: connectivity density0.60.91.30.9-0.9-0.90.8-1.0-0.8-0.90.90.9-0.9-0.9-1.01.0-1.01.11.0-1.1-1.1-0.6
Bone: cortical apparent density0.00.10.30.20.00.00.20.2-0.20.00.0-0.10.10.10.00.20.40.3-0.3-0.3-0.30.6
Bone: cortical area0.30.41.50.7-0.7-0.70.5-0.3-0.5-0.50.60.5-0.6-0.6-0.50.4-0.40.40.5-0.4-1.1-1.2
Bone: cortical porosity0.10.10.4-0.40.30.3-0.40.30.40.3-0.4-0.30.30.30.4-0.60.2-0.4-0.20.40.60.0
Bone: cortical porosity0.20.20.4-0.50.30.3-0.60.40.60.5-0.4-0.40.40.40.5-0.60.3-0.6-0.30.60.5-0.3
Bone: cortical thickness0.00.10.40.2-0.2-0.20.00.2-0.00.00.10.0-0.1-0.1-0.0-0.20.1-0.0-0.10.0-0.6-0.7
Bone: cortical thickness3.33.95.2-2.01.81.8-2.12.12.12.1-2.0-2.02.02.02.1-2.32.0-2.1-2.02.11.70.8
Bone: cortical tissue density0.00.00.30.20.00.00.20.2-0.20.00.0-0.10.10.1-0.00.20.40.3-0.3-0.3-0.30.5
Condit. Reinf. active minus inactive responses1.61.82.61.0-1.4-1.41.0-1.5-1.0-1.31.31.4-1.4-1.4-1.41.4-1.61.31.5-1.3-1.1-1.5
Condit. Reinf. active-inactive response ratio3.33.54.21.6-2.0-2.01.6-1.9-1.6-1.81.81.8-1.9-1.9-2.02.0-2.01.92.0-1.9-1.7-2.0
Condit. Reinf. active responses0.50.71.10.5-0.8-0.80.5-0.9-0.5-0.80.80.8-0.9-0.9-0.90.9-1.00.80.9-0.8-0.6-0.9
Condit. Reinf. inactive responses0.40.50.8-0.70.70.7-0.70.80.70.7-0.7-0.70.70.70.8-0.70.9-0.7-0.90.70.50.7
Incentive salience index mean1.51.82.61.1-1.4-1.41.0-1.4-1.0-1.31.31.3-1.4-1.4-1.41.4-1.61.31.5-1.3-1.1-1.6
Condit. Reinf. lever presses0.81.22.30.9-1.2-1.20.8-1.0-0.8-1.01.01.1-1.1-1.1-1.11.1-1.21.01.1-1.0-1.0-1.5
Condit. Reinf. active minus inactive responses1.11.42.80.9-1.2-1.20.8-1.2-0.8-1.11.11.2-1.2-1.2-1.21.1-1.41.11.3-1.1-1.4-1.7
Condit. Reinf. active-inactive response ratio3.54.07.71.6-2.0-2.01.5-1.9-1.5-1.91.91.9-2.0-2.1-2.01.9-2.21.92.1-1.9-2.3-2.8
Condit. Reinf. active responses0.60.91.20.8-1.0-1.00.7-1.0-0.7-0.90.90.9-0.9-1.0-0.90.9-1.10.91.0-0.9-1.1-1.0
Condit. Reinf. inactive responses0.10.11.1-0.10.30.3-0.10.10.10.2-0.2-0.20.30.30.2-0.20.3-0.2-0.30.20.51.0
Condit. Reinf. lever presses0.71.01.40.9-1.0-1.00.8-1.1-0.8-1.00.91.0-1.0-1.0-1.00.9-1.20.91.1-0.9-1.1-1.2
Condit. Reinf. lever reinforcers received0.60.81.20.8-1.0-1.00.8-1.0-0.8-0.90.90.9-0.9-0.9-0.90.9-1.10.91.0-0.9-1.0-0.8
Conditioned reinforcement - actives3.05.18.42.2-2.6-2.62.2-1.9-2.2-2.12.32.2-2.2-2.3-2.12.1-2.02.12.1-2.0-2.9-2.4
Conditioned reinforcement - inactives6.08.89.93.0-3.1-3.13.0-3.0-3.0-3.03.03.0-3.0-3.0-3.03.0-3.03.03.0-3.0-2.7-2.1
Conditioned locomotion1.31.63.01.6-1.4-1.41.7-1.4-1.7-1.41.31.3-1.2-1.2-1.21.1-1.01.11.1-1.1-0.90.2
Patch foraging indifference point 0 sec0.20.41.5-0.30.50.5-0.40.20.50.5-0.6-0.50.60.60.5-0.50.4-0.5-0.40.61.11.2
Patch foraging indifference point AUC1.21.72.3-1.41.31.3-1.31.51.21.3-1.2-1.31.31.31.4-1.41.5-1.5-1.51.40.71.0
Delay disc. indifference point, 0s delay0.00.00.3-0.2-0.2-0.2-0.10.00.1-0.00.00.0-0.1-0.1-0.20.3-0.10.30.0-0.1-0.2-0.5
Delay disc. indifference point, 16s delay1.61.72.5-1.61.31.3-1.51.41.51.4-1.4-1.41.31.31.3-1.41.3-1.4-1.11.41.00.2
Delay disc. indifference point, 2s delay0.20.30.9-1.00.20.2-0.80.50.80.6-0.6-0.50.50.40.4-0.30.2-0.2-0.40.50.2-0.6
Delay disc. indifference point, 24s delay0.10.20.3-0.60.30.3-0.50.30.50.4-0.4-0.40.40.40.4-0.60.3-0.5-0.20.40.2-0.3
Delay disc. indifference point, 4s delay0.20.20.5-0.70.40.4-0.70.40.70.5-0.5-0.50.40.40.4-0.50.2-0.3-0.30.50.4-0.3
Delay disc. indifference point, 8s delay0.30.40.70.3-0.7-0.70.4-0.8-0.4-0.60.50.6-0.6-0.6-0.60.5-0.80.60.7-0.5-0.5-0.6
Indifference point function ln k0.91.62.01.2-1.2-1.21.3-1.3-1.3-1.31.21.2-1.2-1.2-1.31.4-1.41.41.3-1.4-1.1-0.9
Indifference point function log k0.91.62.01.2-1.2-1.21.3-1.3-1.3-1.31.21.2-1.2-1.2-1.31.4-1.41.41.3-1.4-1.1-0.9
Patch foraging total patch changes 0 sec0.10.21.5-0.20.40.4-0.3-0.00.30.3-0.4-0.40.40.50.4-0.40.2-0.4-0.30.50.91.2
Patch foraging total patch changes 12 sec0.00.00.40.3-0.1-0.10.1-0.1-0.1-0.10.10.1-0.1-0.10.0-0.1-0.0-0.20.00.10.10.7
Patch foraging total patch changes 18 sec0.50.81.1-1.00.90.9-0.90.80.90.8-0.8-0.80.80.81.0-1.00.9-1.1-1.01.10.30.8
Patch foraging total patch changes 24 sec0.91.62.2-1.21.21.2-1.21.11.21.2-1.3-1.21.31.31.3-1.41.2-1.4-1.31.31.21.5
Patch foraging total patch changes 6 sec0.40.61.9-0.70.70.7-0.70.60.70.7-0.7-0.70.80.80.8-0.60.8-0.7-0.90.60.71.4
Patch foraging time to switch 0 sec0.00.00.00.1-0.1-0.1-0.20.10.20.1-0.1-0.10.10.10.0-0.00.1-0.1-0.10.10.20.1
Patch foraging water rate 0 sec0.00.00.0-0.00.10.10.1-0.2-0.2-0.10.00.1-0.0-0.00.0-0.1-0.1-0.00.1-0.10.00.2
Patch foraging water rate 12 sec0.10.20.4-0.70.50.5-0.60.60.60.5-0.5-0.50.50.40.5-0.50.4-0.5-0.50.4-0.0-0.3
Patch foraging water rate 18 sec0.61.01.21.0-0.9-0.91.1-1.0-1.1-1.01.01.0-1.0-1.0-0.90.9-1.01.01.1-1.0-1.0-0.9
Patch foraging water rate 24 sec0.10.10.9-0.50.10.1-0.50.40.50.3-0.2-0.20.20.10.3-0.30.0-0.3-0.20.2-0.1-0.9
Patch foraging water rate 6 sec0.00.00.0-0.10.20.2-0.10.00.10.0-0.0-0.00.0-0.00.1-0.2-0.1-0.1-0.0-0.0-0.0-0.1
Seeking ratio, delayed vs. immediate footshock0.10.10.30.5-0.4-0.40.4-0.3-0.4-0.30.30.3-0.3-0.3-0.40.4-0.40.40.3-0.5-0.20.1
Distance traveled before self-admin0.10.11.10.40.40.40.4-0.0-0.4-0.20.10.1-0.0-0.00.10.00.2-0.00.00.10.31.0
Distance traveled after self-admin0.00.00.40.10.20.20.10.2-0.1-0.10.20.1-0.1-0.2-0.00.10.00.10.2-0.0-0.5-0.6
Extensor digitorum longus weight0.20.91.5-1.00.80.8-1.01.11.01.0-1.0-1.00.90.91.0-1.11.0-1.2-0.91.20.4-0.2
Bone: elastic displacement1.51.72.2-1.41.21.2-1.41.41.41.4-1.3-1.31.31.21.4-1.41.2-1.5-1.31.50.90.3
Bone: elastic work1.41.82.7-1.21.31.3-1.31.41.31.3-1.3-1.31.31.31.4-1.61.3-1.6-1.31.61.20.5
Bone: endosteal estimation0.10.20.3-0.50.60.6-0.50.40.50.4-0.5-0.40.40.40.4-0.40.4-0.5-0.40.50.60.2
Bone: endosteal perimeter0.40.81.00.9-0.9-0.90.8-1.0-0.8-0.90.90.9-0.9-0.9-0.91.0-1.00.91.0-0.9-0.7-0.7
Epididymis fat weight1.03.54.31.6-1.7-1.72.1-1.8-2.1-1.91.91.9-1.9-1.9-1.92.0-1.91.81.9-1.8-2.1-1.6
Delta time in closed arm before/after self-admin0.40.41.5-0.20.80.8-0.10.60.10.5-0.5-0.60.60.60.7-0.60.9-0.6-0.70.60.21.2
Delta time in open arm before/after self-admin0.50.51.00.3-0.7-0.70.4-1.0-0.4-0.70.50.7-0.6-0.5-0.80.8-0.90.90.9-0.90.50.1
Diff in mean of infusions in LGA sessions1.21.52.0-1.31.31.3-1.31.31.31.3-1.2-1.21.21.21.2-1.31.2-1.4-1.11.40.90.3
Delay discount exponential model param0.10.10.40.6-0.2-0.20.5-0.2-0.5-0.30.30.3-0.3-0.2-0.30.4-0.10.20.1-0.4-0.20.3
Extinction: sum of active levers before priming0.40.41.6-0.10.90.9-0.00.70.00.4-0.4-0.50.50.60.7-0.70.9-0.6-0.80.60.01.3
Active lever presses in extinction session 60.10.10.30.5-0.1-0.10.5-0.1-0.5-0.20.20.2-0.1-0.1-0.0-0.00.1-0.10.10.1-0.20.5
Bone: final force0.00.00.20.4-0.1-0.10.2-0.1-0.2-0.20.20.2-0.2-0.2-0.10.1-0.10.00.2-0.0-0.2-0.2
Bone: final moment0.00.00.10.20.20.2-0.00.20.00.1-0.0-0.10.10.10.2-0.20.2-0.3-0.10.30.00.1
Food consumed during 24 hour testing period6.18.410.02.9-2.9-2.92.9-2.8-2.9-2.93.03.0-3.0-3.0-2.92.8-2.92.82.9-2.8-3.2-2.7
Glucose2.23.54.51.7-2.1-2.11.7-1.8-1.7-1.81.91.9-1.9-1.9-1.91.8-1.91.71.9-1.7-2.1-2.0
Heart weight0.60.91.5-1.20.70.7-1.20.91.11.1-1.1-1.01.01.00.9-0.90.8-1.0-0.91.01.2-0.0
Delay discount hyperbolic model param0.10.10.50.7-0.3-0.30.5-0.2-0.5-0.40.40.4-0.3-0.3-0.30.4-0.10.30.2-0.4-0.30.2
Intermittent access intake day 1-15 change0.40.91.30.9-1.0-1.01.0-1.1-1.0-1.00.91.0-1.0-0.9-1.01.0-1.10.91.0-1.0-0.5-0.3
Intermittent access intake escalation0.61.21.71.1-1.1-1.11.1-1.3-1.1-1.21.11.2-1.1-1.1-1.21.2-1.31.11.2-1.1-0.8-0.6
Intermittent access intake escalation 22.12.42.91.6-1.5-1.51.5-1.7-1.5-1.61.61.6-1.6-1.6-1.61.6-1.61.61.6-1.6-1.3-0.8
Intermitt. access day 1 inactive lever presses0.00.10.60.2-0.2-0.20.20.0-0.3-0.20.30.2-0.3-0.3-0.20.3-0.10.30.2-0.3-0.6-0.8
Intermitt. access day 15 inactive lever presses0.50.91.81.3-0.8-0.81.3-1.0-1.4-1.11.11.0-1.0-0.9-0.90.9-0.80.90.9-0.8-0.80.1
Intermitt. access escalation Index0.20.32.7-0.2-0.7-0.7-0.2-0.20.1-0.10.20.2-0.3-0.3-0.40.3-0.50.10.4-0.2-0.6-1.6
Intermittent access day 1 total infusions2.94.76.32.4-2.2-2.22.4-2.1-2.4-2.22.32.2-2.2-2.2-2.12.1-1.92.02.1-1.9-2.5-1.4
Intermittent access day 15 total infusions4.05.96.82.5-2.5-2.52.5-2.6-2.5-2.52.52.5-2.5-2.5-2.52.5-2.52.42.5-2.3-2.3-1.5
Intermittent access terminal intake (last 3 days)4.25.56.02.3-2.5-2.52.3-2.4-2.3-2.42.42.4-2.4-2.4-2.42.3-2.42.32.3-2.2-2.4-1.8
Intermittent access total infusions5.36.27.22.5-2.7-2.72.5-2.5-2.5-2.52.52.5-2.5-2.6-2.52.5-2.52.42.5-2.3-2.7-2.0
Intermittent access day 1 locomotion1.92.53.81.8-1.7-1.71.9-1.7-1.9-1.71.71.6-1.6-1.6-1.51.5-1.41.41.5-1.3-1.5-0.4
Intermittent access day 15 total locomotion1.01.93.21.7-1.2-1.21.8-1.7-1.8-1.51.41.4-1.3-1.2-1.31.3-1.31.31.3-1.3-0.41.0
Intermittent access total locomotion2.02.43.91.9-1.6-1.62.0-1.8-1.9-1.71.61.6-1.6-1.5-1.51.5-1.51.51.5-1.4-0.90.2
Intermittent access standard deviation2.24.66.52.5-2.1-2.12.5-2.3-2.5-2.32.32.3-2.2-2.2-2.12.1-2.02.12.1-2.0-2.1-0.7
Left kidney weight0.73.15.72.2-1.6-1.62.3-1.5-2.3-1.81.91.8-1.7-1.8-1.51.6-1.31.51.6-1.6-2.4-1.0
Right kidney weight1.15.08.73.0-2.1-2.12.9-2.1-2.9-2.32.42.3-2.2-2.2-2.02.1-1.72.12.0-2.2-2.5-0.5
Cocaine induced anxiety0.10.20.3-0.40.60.6-0.40.50.40.4-0.4-0.40.40.40.4-0.40.4-0.3-0.40.30.20.1
Post-drug Anxiety1.81.92.6-1.61.51.5-1.61.61.61.5-1.4-1.41.41.31.4-1.41.3-1.3-1.31.20.80.1
Baseline Anxiety0.70.81.8-1.30.70.7-1.30.91.31.0-1.0-0.90.80.80.7-0.70.6-0.9-0.70.90.6-0.6
Tail length0.62.47.31.2-1.5-1.51.4-0.9-1.4-1.31.51.4-1.5-1.6-1.21.3-1.21.11.3-1.2-2.7-2.6
Length with tail0.93.99.01.8-2.0-2.01.8-1.5-1.8-1.82.01.9-2.0-2.1-1.81.9-1.71.71.9-1.8-3.0-2.7
Length without tail0.72.33.21.8-1.3-1.31.7-1.6-1.6-1.61.61.6-1.5-1.5-1.51.6-1.41.61.5-1.6-1.5-0.5
Times rat made contact with spout0.20.20.30.5-0.5-0.50.5-0.4-0.5-0.40.50.5-0.5-0.5-0.40.4-0.40.40.4-0.4-0.5-0.5
Lifetime Intake5.06.07.52.4-2.6-2.62.4-2.4-2.4-2.42.52.5-2.5-2.5-2.52.4-2.42.42.4-2.3-2.7-2.1
Liver weight, left1.01.62.11.4-1.3-1.31.4-1.2-1.4-1.31.31.3-1.3-1.3-1.21.2-1.21.11.3-1.1-1.4-1.2
Liver weight, right0.91.52.61.5-1.0-1.01.6-1.1-1.6-1.31.41.3-1.3-1.3-1.11.1-1.01.11.2-1.1-1.4-0.6
Locomotor activity0.10.10.6-0.2-0.4-0.40.0-0.40.0-0.20.10.2-0.2-0.2-0.20.2-0.50.30.4-0.30.2-0.8
Locomotor testing distance1.12.03.71.0-1.6-1.61.2-1.4-1.1-1.31.31.4-1.4-1.4-1.41.3-1.61.41.5-1.4-1.2-1.9
Locomotor testing rearing0.20.31.50.2-0.6-0.60.2-0.6-0.1-0.40.40.5-0.5-0.5-0.60.5-0.70.50.6-0.4-0.4-1.2
Locomotion in novel chamber1.31.62.31.3-1.5-1.51.2-1.4-1.2-1.31.31.3-1.3-1.2-1.21.4-1.31.31.3-1.4-0.9-0.5
Locomotion in novel chamber post-restriction0.50.81.5-1.20.90.9-1.11.01.11.0-1.0-1.00.90.91.0-0.90.7-0.9-0.90.80.6-0.2
Fecal boli incidents, locomotor time 15.47.910.5-3.22.92.9-3.13.23.13.0-2.9-2.92.82.82.8-2.82.9-2.9-2.72.92.00.9
Change in fecal boli incidents, locomotor task6.46.38.52.8-2.3-2.32.8-2.9-2.8-2.72.62.6-2.5-2.5-2.52.5-2.62.72.5-2.6-1.8-0.5
Time >=10cm from walls, locomotor time 10.10.20.3-0.50.20.2-0.40.50.40.4-0.3-0.40.30.30.4-0.50.4-0.6-0.30.60.0-0.2
Bouts of movement, locomotor time 10.50.61.1-1.10.30.3-1.01.01.00.9-0.7-0.70.70.60.7-0.90.6-0.9-0.70.9-0.0-1.1
Total resting periods, locomotor time 10.50.51.0-1.00.40.4-0.90.90.90.8-0.6-0.70.60.50.7-0.80.6-0.8-0.60.8-0.1-1.0
Rest time, locomotor task time 10.50.61.2-0.91.11.1-0.81.00.80.8-0.7-0.70.60.60.8-0.90.7-0.9-0.60.90.0-0.4
Distance moved, locomotor task time 11.42.03.01.7-1.7-1.71.4-1.6-1.4-1.51.41.5-1.4-1.4-1.41.3-1.41.41.4-1.4-1.0-0.7
Vertical activity count, locomotor time 10.10.20.60.4-0.8-0.80.3-0.5-0.3-0.40.30.4-0.3-0.3-0.50.5-0.50.50.4-0.50.20.1
Time >=10cm from walls, locomotor time 24.46.57.12.4-2.6-2.62.4-2.5-2.4-2.52.62.5-2.6-2.6-2.62.6-2.52.62.6-2.7-2.6-2.2
Bouts of movement, locomotor time 20.20.30.6-0.50.60.6-0.30.60.30.5-0.5-0.50.60.60.6-0.50.7-0.5-0.60.50.80.7
Total resting periods, locomotor time 20.10.20.4-0.40.50.5-0.20.50.20.4-0.4-0.40.40.40.5-0.40.5-0.4-0.50.40.70.5
Rest time, locomotor task time 21.72.22.7-1.41.71.7-1.41.51.41.4-1.4-1.41.41.41.6-1.61.4-1.6-1.41.61.51.2
Distance moved, locomotor task time 25.05.97.42.4-2.6-2.62.2-2.3-2.2-2.32.42.4-2.4-2.5-2.42.3-2.52.32.5-2.5-2.7-2.7
Vertical activity count, locomotor time 22.23.03.51.7-1.9-1.91.7-1.7-1.7-1.71.71.7-1.7-1.7-1.81.8-1.71.91.7-1.9-1.7-1.2
Light reinforcement 10.10.20.60.6-0.3-0.30.7-0.3-0.7-0.50.50.5-0.5-0.4-0.40.6-0.20.50.4-0.5-0.8-0.0
Light reinforcement 20.00.10.40.7-0.2-0.20.4-0.1-0.4-0.30.30.2-0.2-0.2-0.10.2-0.00.10.2-0.2-0.20.1
Bone: marrow area0.10.20.4-0.50.60.6-0.50.40.50.4-0.5-0.50.50.50.4-0.40.4-0.5-0.40.50.60.3
Bone: maximum diameter0.30.51.00.7-0.8-0.80.6-0.5-0.6-0.60.70.6-0.7-0.7-0.70.7-0.60.60.6-0.6-0.8-1.0
Bone: maximum force0.10.20.60.8-0.3-0.30.6-0.5-0.6-0.50.50.5-0.5-0.5-0.40.4-0.40.30.5-0.3-0.4-0.0
Bone: maximum moment0.00.00.20.40.10.10.2-0.1-0.2-0.10.10.1-0.1-0.1-0.00.00.0-0.10.10.1-0.10.3
Mean time between licks in bursts0.51.21.8-0.91.11.1-1.01.01.01.1-1.1-1.11.21.21.1-1.11.1-1.1-1.11.11.41.3
Mean num. licks in bursts0.00.00.10.10.20.20.20.2-0.20.00.0-0.00.10.10.1-0.10.3-0.1-0.20.1-0.30.3
Cd content in liver3.23.54.91.7-1.9-1.91.7-1.7-1.7-1.81.91.9-1.9-1.9-1.92.0-1.91.91.9-1.9-1.9-2.2
Co content in liver1.11.31.6-1.31.11.1-1.31.21.31.2-1.2-1.21.11.11.2-1.21.1-1.2-1.11.20.90.4
Cu content in liver1.01.21.6-1.21.11.1-1.21.11.21.1-1.1-1.11.11.11.1-1.11.0-1.3-1.01.30.90.4
Fe content in liver0.30.40.8-0.90.50.5-0.80.60.80.7-0.6-0.60.60.50.6-0.60.4-0.6-0.50.60.4-0.4
K content in liver4.24.06.6-1.52.12.1-1.71.91.71.9-1.9-1.92.02.02.1-2.12.1-1.9-2.11.92.12.6
Mg content in liver1.31.31.8-1.11.21.2-1.11.21.11.2-1.1-1.11.11.11.2-1.31.1-1.3-1.11.30.80.5
Mn content in liver1.41.62.1-1.21.31.3-1.31.41.31.3-1.2-1.31.21.21.4-1.51.3-1.4-1.21.41.00.4
Na content in liver0.10.10.50.3-0.2-0.20.3-0.1-0.3-0.30.30.3-0.3-0.4-0.30.3-0.20.30.2-0.3-0.6-0.7
Rb content in liver2.02.32.9-1.51.71.7-1.61.71.61.6-1.5-1.61.51.51.5-1.51.6-1.6-1.61.61.10.8
Se content in liver4.65.46.9-2.52.22.2-2.62.22.62.4-2.4-2.42.42.32.3-2.42.1-2.5-2.22.52.41.3
Sr content in liver0.10.10.2-0.40.30.3-0.20.20.20.3-0.3-0.30.30.30.3-0.30.3-0.1-0.30.10.30.4
Zn content in liver0.30.30.40.7-0.6-0.60.6-0.6-0.6-0.60.60.6-0.6-0.6-0.50.4-0.50.50.6-0.5-0.5-0.3
Bone: minimum diameter0.91.63.51.3-1.3-1.31.2-1.0-1.2-1.21.31.2-1.3-1.3-1.21.0-1.21.01.2-1.0-1.9-1.8
Time in familiar zone, hab. session 10.60.60.9-0.70.80.8-0.70.90.70.8-0.8-0.80.80.80.8-0.61.0-0.5-0.90.50.80.8
Time in novel zone, hab. session 11.21.21.81.0-1.1-1.11.0-1.3-1.0-1.11.01.1-1.1-1.1-1.10.9-1.30.91.3-0.9-1.0-1.1
Total zone transitions, hab. session 12.13.03.81.8-1.6-1.61.8-1.9-1.8-1.81.71.8-1.7-1.7-1.81.9-1.82.01.8-2.0-1.2-0.5
Total locomotion distance, hab. session 10.91.32.11.2-0.9-0.91.3-1.4-1.3-1.21.11.1-1.0-0.9-1.21.3-1.01.41.0-1.4-0.40.9
Locomotion velocity, hab. session 10.60.81.41.0-0.7-0.71.1-1.1-1.1-1.00.80.8-0.7-0.6-0.91.1-0.71.10.7-1.1-0.11.2
Time in familiar zone, hab. session 20.10.11.50.20.00.00.2-0.2-0.2-0.10.00.00.10.1-0.10.30.20.2-0.1-0.20.51.2
Time in novel zone, hab. session 20.20.22.9-0.1-0.2-0.2-0.10.00.1-0.10.20.2-0.3-0.4-0.1-0.1-0.4-0.00.30.0-0.8-1.7
Total zone transitions, hab. session 21.51.92.51.5-1.3-1.31.6-1.4-1.6-1.41.51.4-1.4-1.4-1.41.5-1.21.41.4-1.4-1.4-0.7
Total locomotion distance, hab. session 20.10.11.20.30.10.10.3-0.1-0.3-0.10.10.00.00.1-0.00.10.20.1-0.1-0.10.31.1
Locomotion velocity, hab. session 20.10.11.40.20.20.20.3-0.0-0.3-0.0-0.0-0.00.10.20.10.10.30.0-0.2-0.00.41.2
Novel to familiar place preference ratio0.80.91.21.0-1.0-1.01.1-1.1-1.1-1.01.01.0-0.9-0.9-1.00.9-0.90.91.0-0.9-0.5-0.3
Novelty place preference0.80.81.10.9-1.0-1.01.0-1.1-1.0-1.00.91.0-0.9-0.9-1.00.9-0.90.91.0-0.9-0.5-0.4
Time in novel zone, NPP test0.60.60.80.7-0.8-0.80.8-0.9-0.8-0.80.80.8-0.8-0.8-0.80.8-0.80.80.9-0.8-0.4-0.4
Total zone transitions, NPP test0.50.71.2-1.10.80.8-1.00.81.00.9-0.9-0.90.90.90.7-0.60.7-0.7-0.80.71.00.5
Total locomotion distance, NPP test0.50.61.8-0.80.90.9-0.70.60.70.7-0.8-0.80.80.90.6-0.50.7-0.6-0.80.61.21.3
Locomotion velocity, NPP test0.40.62.2-0.60.80.8-0.60.50.60.6-0.7-0.70.70.80.6-0.50.7-0.6-0.70.61.11.5
Intraocular pressure0.00.00.4-0.20.00.0-0.1-0.10.10.1-0.1-0.10.10.10.1-0.2-0.1-0.20.00.30.60.2
Delta distance traveled before/after self-admin0.30.31.4-0.70.20.2-0.70.80.70.6-0.4-0.50.40.30.5-0.50.5-0.4-0.40.4-0.5-1.2
Delta ambulatory time before/after self-admin0.10.22.2-0.4-0.1-0.1-0.30.30.30.2-0.0-0.1-0.0-0.10.1-0.10.0-0.00.10.0-0.7-1.5
Parametrial fat weight0.10.20.40.7-0.5-0.50.6-0.5-0.6-0.40.40.4-0.4-0.4-0.30.3-0.30.40.4-0.4-0.30.3
Pavlov. Cond. lever latency0.60.81.6-0.80.80.8-0.80.70.80.9-0.9-0.90.90.90.9-0.80.9-0.8-0.90.80.91.3
Pavlov. Cond. magazine entry latency0.70.91.31.1-0.9-0.91.1-0.7-1.1-1.01.01.0-1.0-1.0-0.91.0-0.70.90.9-0.9-1.1-0.9
Pavlov. Cond. change in total contacts0.10.20.3-0.10.50.5-0.20.50.20.4-0.3-0.40.40.40.4-0.40.5-0.5-0.40.50.50.3
Pavlov. Cond. index score0.30.40.70.8-0.5-0.50.8-0.5-0.8-0.70.70.7-0.7-0.7-0.60.6-0.50.60.6-0.6-0.6-0.6
Pavlov. Cond. latency score0.40.50.80.9-0.5-0.50.8-0.5-0.8-0.70.70.7-0.7-0.7-0.60.6-0.50.60.6-0.6-0.7-0.5
Pavlov. Cond. lever contacts0.60.71.90.8-0.8-0.80.7-0.7-0.7-0.80.90.8-0.9-0.9-0.90.8-0.80.80.9-0.8-0.9-1.4
Pavlov. Cond. magazine entry number0.91.11.6-1.21.01.0-1.20.81.21.1-1.1-1.11.11.11.0-1.10.8-1.1-1.01.11.20.9
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.30.10.1-0.3-0.10.30.1-0.2-0.10.10.10.0-0.1-0.2-0.30.10.30.40.0
Pavlov. Cond. lever-magazine prob. diff.0.30.40.60.8-0.5-0.50.7-0.5-0.7-0.60.70.6-0.7-0.7-0.60.6-0.50.60.6-0.6-0.6-0.6
Pavlov. Cond. response bias0.91.11.61.1-1.0-1.01.1-0.8-1.0-1.01.11.1-1.1-1.1-1.11.1-0.91.11.0-1.1-1.1-1.2
Pavlov. Cond. lever latency1.72.43.3-1.51.61.6-1.31.71.31.5-1.5-1.61.61.61.6-1.61.8-1.6-1.71.51.21.5
Pavlov. Cond. magazine entry latency0.70.91.51.2-1.0-1.01.0-1.2-1.0-1.00.91.0-0.9-0.9-1.00.9-1.00.91.0-0.8-0.6-0.3
Pavlov. Cond. change in total contacts0.91.52.01.1-1.3-1.31.1-1.3-1.1-1.21.21.2-1.2-1.2-1.21.2-1.41.21.3-1.1-1.0-1.2
Pavlov. Cond. index score1.92.53.21.6-1.7-1.71.4-1.8-1.4-1.61.51.6-1.6-1.6-1.61.5-1.81.51.7-1.5-1.3-1.3
Pavlov. Cond. latency score2.33.03.81.8-1.8-1.81.6-1.9-1.6-1.81.71.8-1.8-1.8-1.81.7-2.01.71.9-1.6-1.4-1.3
Pavlov. Cond. lever contacts2.53.54.71.8-2.0-2.01.6-2.0-1.6-1.81.81.9-1.9-1.9-1.91.9-2.21.92.0-1.8-1.5-1.8
Pavlov. Cond. magazine entry number0.70.81.2-1.11.01.0-1.01.11.01.0-0.9-1.00.90.90.9-0.81.0-0.8-1.00.80.50.4
Pavlov. Cond. intertrial magazine entries0.20.30.6-0.80.40.4-0.60.60.60.5-0.5-0.50.50.50.5-0.50.5-0.5-0.50.40.3-0.2
Pavlov. Cond. lever-magazine prob. diff.1.62.12.71.5-1.6-1.61.3-1.6-1.3-1.41.41.5-1.5-1.5-1.51.4-1.61.41.6-1.3-1.2-1.3
Pavlov. Cond. response bias2.02.73.61.6-1.8-1.81.4-1.8-1.4-1.61.61.7-1.7-1.7-1.71.6-1.91.61.8-1.6-1.3-1.6
Time in closed arm before self-admin2.63.312.31.1-2.1-2.10.9-1.6-0.9-1.51.61.6-1.8-1.8-1.91.7-2.11.61.9-1.5-1.8-3.5
Time in closed arm after self-admin0.70.73.10.5-0.9-0.90.6-0.8-0.6-0.70.70.8-0.8-0.9-0.90.7-1.00.60.9-0.6-1.0-1.7
Time in open arm before self-admin4.44.87.1-1.92.32.3-1.82.21.82.2-2.2-2.22.32.32.3-2.22.4-2.3-2.32.32.02.7
Time in open arm after self-admin1.71.87.5-1.01.41.4-0.90.80.91.1-1.3-1.21.31.41.2-1.11.1-1.0-1.11.02.22.7
Bone: periosteal estimation0.00.00.20.00.10.1-0.10.20.10.1-0.1-0.10.10.00.0-0.10.1-0.2-0.10.2-0.1-0.4
Bone: periosteal perimeter1.22.12.71.6-1.5-1.51.5-1.4-1.5-1.41.51.5-1.5-1.5-1.41.3-1.31.41.4-1.4-1.6-1.2
Bone: post-yield work0.00.00.10.2-0.2-0.20.1-0.3-0.1-0.20.10.2-0.2-0.2-0.30.3-0.30.20.3-0.2-0.0-0.0
Progressive ratio test 1 active lever presses3.44.15.22.1-2.3-2.32.0-1.9-2.0-2.02.12.1-2.1-2.1-2.01.9-2.01.92.0-1.8-2.3-1.9
Progressive ratio test 1 breakpoint3.44.15.42.1-2.2-2.22.0-1.9-2.0-2.02.12.0-2.1-2.1-2.01.9-1.91.92.0-1.8-2.3-2.0
Progressive ratio test 1 inactive lever presses1.11.62.31.5-1.2-1.21.5-1.2-1.5-1.41.41.4-1.3-1.3-1.31.2-1.21.21.3-1.1-1.1-0.8
Progressive ratio test 2 active lever presses6.17.18.22.9-2.9-2.92.8-2.7-2.8-2.72.82.7-2.7-2.7-2.62.5-2.62.62.6-2.6-2.6-1.8
Progressive ratio test 2 breakpoint6.57.48.52.9-2.9-2.92.8-2.8-2.8-2.82.82.8-2.8-2.8-2.72.6-2.62.62.7-2.6-2.7-1.8
Progressive ratio test 2 inactive lever presses2.94.76.12.5-2.3-2.32.4-2.2-2.4-2.32.32.3-2.3-2.2-2.12.0-2.02.12.1-2.1-2.1-1.2
Incentive Sensitization - Responses3.75.26.72.6-2.4-2.42.6-2.4-2.5-2.42.42.3-2.3-2.3-2.22.1-2.12.22.2-2.3-2.2-1.1
Incentive Sensitization - Breakpoint3.84.96.42.5-2.3-2.32.5-2.3-2.5-2.32.32.3-2.2-2.2-2.22.1-2.12.12.1-2.2-2.0-1.0
Sum of active levers in priming session hrs 5-61.61.52.4-0.81.51.5-0.81.30.81.1-1.1-1.11.21.21.4-1.31.5-1.2-1.31.10.91.4
Progressive ratio0.30.50.70.8-0.6-0.60.8-0.7-0.8-0.80.80.7-0.7-0.7-0.70.6-0.60.80.7-0.7-0.7-0.6
Food seeking constrained by brief footshock0.70.91.21.1-0.8-0.81.0-1.0-1.0-1.01.01.0-1.0-1.0-0.90.9-0.90.71.0-0.7-1.1-0.7
Seeking ratio, punishment vs. effort0.00.10.1-0.30.20.2-0.30.10.30.2-0.3-0.20.30.20.2-0.10.1-0.3-0.20.30.40.3
Retroperitoneal fat weight11.348.152.37.1-6.8-6.87.2-7.1-7.1-7.17.17.1-7.0-7.0-7.07.2-7.07.17.1-7.2-6.7-4.5
Reaction time number correct0.10.11.0-0.30.10.1-0.40.30.40.2-0.2-0.10.10.00.3-0.4-0.0-0.30.00.2-0.2-1.0
Reaction time mean minus median0.10.20.70.8-0.2-0.20.8-0.5-0.8-0.60.50.5-0.4-0.4-0.30.4-0.20.20.2-0.2-0.20.8
Reaction time mean minus median AUC0.10.20.60.8-0.1-0.10.8-0.5-0.8-0.60.60.5-0.5-0.4-0.40.5-0.30.40.3-0.4-0.40.5
Reaction time num false alarms1.52.12.9-1.51.51.5-1.51.41.51.4-1.5-1.51.41.41.6-1.71.4-1.6-1.31.61.20.7
Reaction time num false alarms AUC2.03.14.2-1.91.71.7-1.91.81.91.8-1.8-1.81.81.71.9-2.01.6-2.0-1.62.01.50.6
Reaction time trials correct on left0.10.11.0-0.30.10.1-0.40.30.40.2-0.2-0.10.10.00.3-0.4-0.0-0.30.00.2-0.2-1.0
Reaction time trials on left0.10.10.8-0.30.20.2-0.40.40.50.3-0.2-0.20.20.10.4-0.50.1-0.4-0.10.3-0.1-0.9
Reaction time mean0.20.40.50.7-0.7-0.70.7-0.5-0.7-0.60.70.6-0.6-0.6-0.60.6-0.50.40.5-0.5-0.7-0.4
Reaction time mean AUC0.40.60.90.7-0.8-0.80.8-0.7-0.8-0.80.90.8-0.8-0.8-0.80.8-0.70.70.7-0.7-1.0-0.7
Median of all reaction times0.40.50.90.7-0.9-0.90.7-0.6-0.7-0.70.80.7-0.7-0.7-0.70.7-0.60.60.6-0.6-0.9-0.8
Reaction time omissions1.01.42.2-0.91.31.3-0.91.10.91.1-1.1-1.11.21.21.3-1.31.3-1.3-1.31.31.21.5
Reaction time false alarm rate2.33.23.8-1.91.81.8-1.71.71.71.8-1.8-1.81.81.91.9-1.91.8-1.9-1.72.01.81.5
Reaction time premature initiation rate0.20.20.5-0.60.10.1-0.50.70.50.5-0.4-0.50.40.30.4-0.40.4-0.6-0.40.60.3-0.7
Reaction time premature initiations0.20.31.0-0.70.20.2-0.70.80.70.6-0.5-0.50.40.40.6-0.70.4-0.7-0.40.70.1-1.0
Std. dev. reaction times0.00.10.20.3-0.1-0.10.5-0.2-0.4-0.30.30.3-0.3-0.2-0.10.2-0.10.10.1-0.0-0.10.3
Reaction time trials completed0.10.10.8-0.30.20.2-0.40.40.50.3-0.2-0.20.20.10.4-0.50.1-0.4-0.10.3-0.1-0.9
Reaction time trials AUC0.00.11.2-0.2-0.0-0.0-0.30.20.30.1-0.1-0.0-0.0-0.10.2-0.3-0.1-0.20.10.1-0.3-1.1
Run reversals in cocaine runway, females0.20.20.30.5-0.4-0.40.4-0.3-0.4-0.40.50.4-0.4-0.4-0.30.3-0.20.40.3-0.3-0.5-0.5
Run reversals in cocaine runway, males4.64.65.3-2.02.32.3-2.02.22.02.1-2.1-2.22.22.22.2-2.22.3-2.2-2.22.22.02.0
Latency to leave start box in cocaine runway0.40.52.8-0.10.50.5-0.30.30.30.4-0.5-0.50.60.70.6-0.50.6-0.6-0.70.71.21.7
Latency to leave start box in cocaine runway, F0.20.33.00.50.10.10.3-0.2-0.3-0.1-0.1-0.00.20.30.1-0.10.3-0.4-0.30.40.91.7
Latency to leave start box in cocaine runway, M0.40.40.7-0.80.70.7-0.80.70.80.6-0.6-0.60.60.60.6-0.60.6-0.4-0.60.50.60.2
Std. dev. time between licks in bursts0.30.40.8-0.90.50.5-0.80.60.80.7-0.7-0.60.60.50.6-0.70.3-0.7-0.50.70.7-0.5
Total sessions with >9 infusions2.22.73.61.7-1.9-1.91.7-1.5-1.6-1.61.71.6-1.6-1.7-1.61.5-1.51.61.5-1.4-1.9-1.3
Short access day 1 total inactive lever presses0.91.21.41.1-1.1-1.11.0-1.1-1.0-1.11.11.1-1.1-1.1-1.21.2-1.21.21.1-1.1-1.0-1.0
Short access day 10 total inactive lever presses0.00.10.30.3-0.1-0.10.4-0.4-0.5-0.40.30.3-0.2-0.2-0.20.3-0.20.40.3-0.40.50.6
Short access day 1 total infusions3.54.67.52.0-2.3-2.31.9-1.9-1.8-2.12.22.1-2.2-2.2-2.12.0-2.02.02.1-1.8-2.7-2.6
Short access day 10 total infusions3.13.94.92.2-2.2-2.22.1-2.1-2.1-2.12.12.1-2.0-2.0-2.01.9-2.01.91.9-1.7-1.8-1.1
Short access total infusions3.64.66.42.2-2.4-2.42.2-2.1-2.1-2.12.22.2-2.2-2.2-2.12.0-2.02.02.1-1.9-2.5-1.9
Short access day 1 locomotion2.63.23.91.8-2.0-2.01.8-1.9-1.8-1.81.81.8-1.8-1.8-1.81.8-1.81.81.8-1.7-1.5-1.1
Short access day 10 total locomotion2.24.26.82.5-2.0-2.02.6-2.3-2.6-2.22.22.1-2.1-2.0-1.91.9-1.92.01.9-1.8-1.30.2
Short access total locomotion3.13.85.32.3-2.1-2.12.3-2.1-2.3-2.12.02.0-2.0-1.9-1.91.9-1.81.91.9-1.8-1.4-0.3
One hour access (0.3 mA shock)4.75.48.22.8-2.3-2.32.9-2.5-2.8-2.52.52.4-2.3-2.3-2.22.2-2.12.32.2-2.3-1.9-0.1
Compulsive drug intake4.14.86.5-1.92.22.2-1.92.11.92.1-2.2-2.22.22.32.3-2.32.4-2.2-2.32.12.32.5
One hour access (shock baseline)6.610.211.13.3-3.3-3.33.3-3.3-3.3-3.33.33.3-3.3-3.2-3.23.2-3.23.23.2-3.2-3.0-2.0
Social response proportion4.24.85.5-2.22.22.2-2.32.32.32.3-2.2-2.22.22.22.2-2.22.3-2.1-2.32.22.01.5
Social responses0.00.00.10.3-0.2-0.20.3-0.1-0.3-0.20.20.2-0.2-0.2-0.10.0-0.10.20.1-0.1-0.10.1
Social time1.82.43.7-1.91.21.2-1.81.61.71.7-1.7-1.71.61.61.5-1.61.5-1.6-1.51.61.50.5
Soleus weight1.44.04.9-1.82.02.0-1.81.91.82.0-2.0-2.02.12.12.0-2.02.1-2.0-2.11.92.02.2
Bone: stiffness0.61.01.81.3-0.9-0.91.2-1.0-1.2-1.11.11.1-1.0-1.0-1.01.1-1.01.01.0-1.0-0.8-0.3
Tibialis anterior weight2.79.311.0-3.23.03.0-3.33.23.33.2-3.1-3.23.13.03.1-3.23.0-3.3-3.13.32.41.3
Time to tail flick, vehicle, before self-admin2.32.43.51.8-1.4-1.41.9-1.8-1.9-1.71.61.6-1.5-1.5-1.51.5-1.41.61.4-1.8-0.90.1
Time to tail flick, vehicle, after self-admin4.25.67.52.1-2.7-2.72.1-2.4-2.1-2.32.32.3-2.4-2.4-2.42.5-2.52.32.3-2.2-2.4-2.4
Time to tail flick, test, before self-admin1.92.02.81.1-1.2-1.21.2-1.5-1.2-1.41.41.4-1.5-1.5-1.51.6-1.71.61.4-1.6-1.3-1.5
Time to tail flick, test, after self-admin4.85.07.31.7-2.1-2.11.7-2.5-1.7-2.22.12.3-2.3-2.3-2.42.4-2.72.32.5-2.2-2.0-2.5
Delta time to tail flick, vehicle, before/after SA0.30.32.4-0.1-0.6-0.6-0.1-0.20.1-0.20.20.3-0.3-0.4-0.40.5-0.60.30.4-0.1-0.7-1.5
Delta time to tail flick, test, before/after SA0.10.10.30.2-0.6-0.60.0-0.5-0.0-0.30.30.3-0.3-0.3-0.40.3-0.50.30.5-0.2-0.2-0.4
Tibia length0.20.71.4-0.70.80.8-0.91.20.90.9-0.7-0.80.70.60.8-0.80.8-1.0-0.81.00.0-0.8
Ambulatory time before self-admin0.10.10.30.00.50.5-0.00.40.00.2-0.1-0.20.20.20.3-0.20.4-0.3-0.30.30.20.6
Ambulatory time after self-admin0.30.32.30.2-0.3-0.30.3-0.0-0.3-0.40.50.4-0.5-0.6-0.40.4-0.40.40.5-0.4-1.0-1.5
Bone: tissue strength0.20.22.00.20.50.50.1-0.1-0.1-0.0-0.1-0.10.10.20.1-0.10.1-0.1-0.10.10.71.4
Total heroin consumption1.11.21.9-0.80.90.9-0.91.30.91.1-1.0-1.11.11.11.3-1.31.4-1.3-1.31.30.91.2
Bone: trabecular number0.50.91.10.9-1.0-1.00.8-1.0-0.8-0.90.90.9-0.9-0.9-0.90.9-1.01.01.0-1.0-0.9-0.6
Bone: trabecular spacing0.10.20.40.6-0.4-0.40.5-0.4-0.5-0.40.40.4-0.4-0.4-0.40.6-0.30.40.3-0.4-0.20.1
Bone: trabecular thickness0.50.60.80.9-0.7-0.70.8-0.8-0.8-0.80.80.8-0.8-0.8-0.70.7-0.80.80.8-0.8-0.8-0.4
Bone: trabecular tissue density0.91.34.0-0.71.31.3-0.81.10.81.0-1.0-1.11.11.21.1-0.91.3-0.8-1.20.81.52.0
Water consumed over 24 hours0.50.61.40.7-0.9-0.90.7-0.7-0.7-0.80.80.8-0.8-0.9-0.70.6-0.90.60.8-0.6-0.9-1.2
Number of responses in last shaping day3.53.84.82.0-2.2-2.21.8-1.8-1.7-1.92.02.0-2.0-2.0-2.01.9-1.91.91.9-1.8-2.1-2.0