Hub : Genes

C3h11orf91

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye intron excision ratio chr3_90482837_90486337 0.48 0.36 1.9e-03 0.26 0.25 0.16 0.26 6.3e-05 8.2e-05 1.9e-03 6.5e-05
2 Eye intron excision ratio chr3_90485168_90486337 0.42 0.36 4.0e-03 0.23 0.22 0.16 0.23 1.7e-04 3.1e-04 1.8e-03 1.7e-04
3 Adipose gene expression C3h11orf91 0.49 0.14 0.0e+00 0.55 0.55 0.56 0.55 2.6e-73 2.4e-73 1.5e-74 8.3e-74
4 Adipose intron excision ratio chr3_90482837_90486337 0.06 0.05 1.3e-07 0.05 0.05 0.04 0.05 1.5e-06 3.5e-06 1.5e-05 3.4e-06
5 Adipose alternative TSS XM_017591901.2 0.03 0.02 8.5e-04 0.02 0.02 0.02 0.02 1.8e-03 1.4e-03 3.0e-03 3.5e-03
6 Adipose alternative TSS XM_039105441.1 0.03 0.02 9.8e-04 0.02 0.02 0.02 0.02 2.1e-03 1.8e-03 3.6e-03 4.3e-03
7 Adipose alternative TSS XM_017591901.2 0.03 0.03 1.9e-04 0.03 0.03 0.03 0.03 4.4e-04 2.9e-04 4.0e-04 7.0e-04
8 Adipose alternative TSS XM_039105441.1 0.03 0.03 1.8e-04 0.03 0.03 0.03 0.03 4.5e-04 3.0e-04 4.2e-04 6.9e-04
9 Adipose isoform ratio XM_039105441.1 0.41 0.15 0.0e+00 0.36 0.38 0.38 0.38 2.8e-42 1.5e-44 9.0e-45 7.3e-44
10 Brain isoform ratio XM_039105441.1 0.05 0.04 1.6e-05 0.05 0.06 0.05 0 2.9e-05 1.4e-06 2.5e-05 2.3e-01
11 Liver gene expression C3h11orf91 0.18 0.12 0.0e+00 0.14 0.14 0.14 0.14 9.0e-16 2.9e-15 1.7e-15 1.2e-15

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.40.71.31.11.00.80.90.9-0.90.9-0.9-0.60.80.4
Area under the delay curve0.30.30.6-0.2-0.2-0.5-0.0-0.60.6-0.60.60.8-0.6-0.8
BMI with tail0.10.30.60.70.50.50.80.5-0.50.5-0.5-0.60.40.3
BMI without tail0.51.01.41.00.91.01.20.9-0.90.9-0.9-1.10.91.1
Body weight0.73.03.71.51.51.71.61.8-1.81.8-1.8-1.91.81.8
Weight adjusted by age1.92.12.5-1.4-1.5-1.6-1.6-1.41.4-1.41.41.3-1.5-1.5
Bone surface0.40.71.11.01.00.81.00.8-0.80.8-0.8-0.50.80.6
Bone volume1.01.72.61.61.61.31.51.2-1.21.3-1.3-0.91.20.9
Breakpoint value in progressive ratio session0.70.81.7-1.1-1.3-0.9-1.0-0.80.8-0.80.80.5-0.7-0.5
Number of licking bursts0.20.20.40.70.70.50.70.3-0.30.4-0.4-0.30.40.1
Context. condit. distance diff. score4.14.96.02.02.02.22.02.3-2.32.3-2.3-2.42.22.4
Locomotion velocity, session 10.10.10.2-0.3-0.2-0.2-0.4-0.40.4-0.40.40.3-0.3-0.1
Locomotion distance, session 10.10.10.3-0.10.0-0.3-0.1-0.40.4-0.40.30.6-0.3-0.5
Locomotion velocity, session 20.00.00.00.00.0-0.10.0-0.00.0-0.00.00.2-0.00.1
Locomotion distance, session 20.10.20.20.50.50.40.50.4-0.40.4-0.4-0.40.40.4
Locomotion velocity, session 30.10.10.50.20.3-0.20.2-0.30.3-0.30.30.7-0.3-0.5
Locomotion distance, session 30.10.10.30.40.50.20.40.1-0.10.1-0.10.20.10.1
Stereotopy head waving bouts, day 30.30.40.9-0.3-0.2-0.5-0.3-0.70.7-0.60.60.8-0.6-0.9
Stereotopy head waving duration, day 30.30.40.60.70.80.60.70.5-0.50.6-0.6-0.50.60.4
Locomotion velocity, session 70.10.10.4-0.1-0.10.2-0.00.4-0.30.3-0.3-0.50.30.7
Locomotion distance, session 70.20.30.8-0.8-0.9-0.5-0.8-0.30.3-0.40.40.1-0.40.1
Stereotopy head waving bouts, day 70.10.10.30.30.4-0.10.3-0.30.3-0.20.20.6-0.2-0.3
Stereotopy head waving duration, day 70.00.10.20.20.3-0.10.2-0.20.2-0.20.20.5-0.1-0.2
Locomotion velocity, session 80.60.71.40.60.60.80.60.9-0.90.9-0.9-1.00.91.2
Locomotion distance, session 83.45.05.92.12.12.22.22.3-2.32.3-2.3-2.22.32.4
Degree of sensitization distance0.20.20.5-0.7-0.7-0.0-0.60.1-0.10.1-0.1-0.70.10.5
Degree of sensitization stereotypy0.20.20.70.10.2-0.30.1-0.50.5-0.50.50.8-0.4-0.4
Conditioned locomotion4.95.77.0-2.1-2.0-2.4-2.0-2.62.6-2.52.52.7-2.4-2.4
Cocaine response after cond. corrected3.03.33.7-1.8-1.7-1.8-1.8-1.81.8-1.81.81.9-1.8-1.9
Cocaine response after cond. not corrected0.50.60.7-0.7-0.7-0.7-0.7-0.80.8-0.80.80.8-0.7-0.8
Cocaine response before conditioning6.68.08.52.92.82.92.92.8-2.82.8-2.8-2.72.82.7
Saline control response0.40.61.11.01.10.71.00.6-0.60.6-0.7-0.30.70.6
Bone: connectivity density0.50.81.21.11.00.81.10.9-0.90.9-0.9-0.70.80.5
Bone: cortical apparent density0.10.10.4-0.4-0.6-0.1-0.40.0-0.00.0-0.0-0.40.00.4
Bone: cortical area0.60.92.60.50.30.80.51.0-1.00.9-0.9-1.21.01.6
Bone: cortical porosity0.40.50.7-0.6-0.6-0.7-0.6-0.70.7-0.70.70.8-0.7-0.7
Bone: cortical porosity0.10.10.2-0.4-0.4-0.4-0.4-0.30.3-0.30.30.4-0.4-0.2
Bone: cortical thickness0.20.31.20.2-0.10.40.20.4-0.40.4-0.4-0.70.51.1
Bone: cortical thickness2.52.94.1-1.9-2.0-1.8-1.8-1.71.7-1.71.71.5-1.7-1.4
Bone: cortical tissue density0.10.10.3-0.3-0.5-0.0-0.30.1-0.10.1-0.1-0.40.10.4
Condit. Reinf. active minus inactive responses1.51.62.01.41.41.31.41.3-1.31.3-1.3-1.11.21.1
Condit. Reinf. active-inactive response ratio3.53.84.12.02.01.92.02.0-2.02.0-2.0-1.81.91.6
Condit. Reinf. active responses0.40.50.80.90.90.70.80.7-0.70.7-0.7-0.50.70.5
Condit. Reinf. inactive responses0.50.70.8-0.8-0.7-0.8-0.9-0.90.9-0.80.80.8-0.8-0.6
Incentive salience index mean1.41.72.21.51.41.31.41.3-1.31.3-1.3-1.21.31.1
Condit. Reinf. lever presses1.21.51.91.41.31.21.31.2-1.21.2-1.2-1.21.31.0
Condit. Reinf. active minus inactive responses2.02.53.01.51.41.61.51.6-1.61.6-1.6-1.71.61.6
Condit. Reinf. active-inactive response ratio5.45.76.32.22.12.42.22.5-2.52.4-2.4-2.52.42.5
Condit. Reinf. active responses1.11.51.61.21.21.21.21.3-1.31.2-1.2-1.21.21.1
Condit. Reinf. inactive responses0.10.20.4-0.1-0.1-0.4-0.1-0.40.4-0.40.40.6-0.4-0.6
Condit. Reinf. lever presses1.01.31.61.11.01.21.01.2-1.21.2-1.2-1.31.11.2
Condit. Reinf. lever reinforcers received1.01.41.51.21.11.21.21.2-1.21.2-1.2-1.21.11.0
Conditioned reinforcement - actives4.94.95.92.41.72.12.42.2-2.22.2-2.2-2.32.22.4
Conditioned reinforcement - inactives8.89.911.83.43.23.13.23.2-3.23.2-3.2-2.93.12.8
Conditioned locomotion1.41.72.91.71.41.21.51.3-1.31.3-1.3-1.01.20.9
Patch foraging indifference point 0 sec1.01.63.2-0.6-0.6-1.2-0.8-1.31.3-1.31.31.8-1.3-1.8
Patch foraging indifference point AUC1.01.22.1-1.3-1.4-1.2-1.1-1.11.1-1.11.10.8-1.0-0.7
Delay disc. indifference point, 0s delay0.00.00.10.30.00.10.30.1-0.10.1-0.1-0.10.10.1
Delay disc. indifference point, 16s delay1.21.21.6-1.3-1.2-1.1-0.7-1.11.1-1.11.11.1-1.1-1.1
Delay disc. indifference point, 2s delay0.10.10.1-0.0-0.3-0.3-0.0-0.30.3-0.30.30.2-0.3-0.2
Delay disc. indifference point, 24s delay0.30.30.5-0.3-0.3-0.5-0.1-0.60.6-0.60.60.7-0.6-0.7
Delay disc. indifference point, 4s delay0.10.20.3-0.1-0.2-0.4-0.2-0.50.5-0.40.40.5-0.4-0.5
Delay disc. indifference point, 8s delay0.20.20.50.70.70.30.70.2-0.20.2-0.20.00.2-0.1
Indifference point function ln k0.81.11.61.31.31.11.01.1-1.11.1-1.1-0.81.00.7
Indifference point function log k0.81.11.61.31.31.11.01.1-1.11.1-1.1-0.81.00.7
Patch foraging total patch changes 0 sec0.91.53.2-0.5-0.4-1.1-0.7-1.21.2-1.21.21.8-1.3-1.8
Patch foraging total patch changes 12 sec0.00.00.00.10.20.00.10.0-0.00.1-0.0-0.00.00.1
Patch foraging total patch changes 18 sec0.81.11.7-0.9-0.8-1.1-0.5-1.11.1-1.11.11.3-1.1-1.2
Patch foraging total patch changes 24 sec1.82.13.2-1.1-1.2-1.6-0.9-1.51.5-1.51.51.7-1.6-1.8
Patch foraging total patch changes 6 sec0.71.02.0-0.6-0.6-1.1-0.5-1.11.1-1.11.11.4-1.1-1.2
Patch foraging time to switch 0 sec0.00.00.1-0.2-0.2-0.20.0-0.10.1-0.10.10.0-0.1-0.2
Patch foraging water rate 0 sec0.00.00.20.30.1-0.1-0.0-0.10.1-0.10.10.4-0.1-0.2
Patch foraging water rate 12 sec0.00.00.1-0.2-0.4-0.1-0.3-0.00.0-0.00.0-0.0-0.10.0
Patch foraging water rate 18 sec0.91.21.51.11.11.10.91.1-1.11.1-1.1-1.21.11.0
Patch foraging water rate 24 sec0.10.20.50.3-0.10.30.20.5-0.50.5-0.5-0.70.50.6
Patch foraging water rate 6 sec0.00.00.00.20.0-0.10.00.0-0.00.0-0.00.10.0-0.1
Seeking ratio, delayed vs. immediate footshock0.30.40.60.70.50.60.80.6-0.60.6-0.6-0.70.60.6
Distance traveled before self-admin0.70.71.10.60.80.90.70.9-0.90.9-0.9-1.10.91.0
Distance traveled after self-admin1.41.52.80.70.81.21.01.2-1.21.2-1.2-1.71.31.6
Extensor digitorum longus weight0.20.91.3-1.1-1.1-1.0-1.1-0.90.9-0.90.90.9-0.9-0.8
Bone: elastic displacement1.01.11.9-1.3-1.4-1.1-1.3-1.01.0-1.01.00.8-1.0-0.5
Bone: elastic work0.81.01.9-1.3-1.4-1.0-1.2-0.90.9-0.90.90.7-1.0-0.5
Bone: endosteal estimation0.20.50.8-0.8-0.5-0.7-0.9-0.70.7-0.70.70.7-0.7-0.6
Bone: endosteal perimeter0.20.50.70.70.80.70.60.6-0.60.7-0.7-0.60.70.8
Epididymis fat weight0.92.02.61.61.41.41.31.5-1.51.4-1.4-1.31.41.3
Delta time in closed arm before/after self-admin0.10.10.4-0.5-0.3-0.2-0.6-0.20.2-0.10.2-0.1-0.1-0.1
Delta time in open arm before/after self-admin0.60.61.2-0.1-0.2-0.6-0.3-0.90.9-0.90.91.1-0.9-1.0
Diff in mean of infusions in LGA sessions0.00.10.2-0.3-0.5-0.1-0.30.0-0.00.00.0-0.30.00.3
Delay discount exponential model param0.40.40.70.30.30.60.10.7-0.70.7-0.7-0.80.70.8
Extinction: sum of active levers before priming0.20.20.5-0.10.00.4-0.20.5-0.50.5-0.5-0.70.50.7
Active lever presses in extinction session 60.20.20.40.20.30.50.10.6-0.60.5-0.5-0.50.50.6
Bone: final force0.10.20.6-0.1-0.10.3-0.20.4-0.40.4-0.4-0.60.40.8
Bone: final moment0.10.10.3-0.5-0.5-0.1-0.60.1-0.10.1-0.1-0.30.10.4
Food consumed during 24 hour testing period7.69.29.82.93.03.12.93.1-3.13.1-3.1-3.13.13.0
Glucose2.64.04.91.81.72.01.72.0-2.02.0-2.0-2.22.02.2
Heart weight0.10.10.6-0.5-0.4-0.2-0.8-0.20.2-0.20.2-0.2-0.2-0.1
Delay discount hyperbolic model param0.30.30.50.20.20.50.10.6-0.60.6-0.6-0.70.60.7
Intermittent access intake day 1-15 change0.20.20.50.50.50.30.70.4-0.40.3-0.3-0.30.30.3
Intermittent access intake escalation0.40.40.90.70.80.60.90.6-0.60.6-0.6-0.50.50.5
Intermittent access intake escalation 22.82.83.51.71.91.71.91.6-1.61.6-1.6-1.71.61.6
Intermitt. access day 1 inactive lever presses0.40.40.9-0.3-0.20.3-0.40.9-0.90.8-0.8-0.90.70.7
Intermitt. access day 15 inactive lever presses3.23.54.21.61.61.81.42.0-2.02.0-2.0-2.01.91.9
Intermitt. access escalation Index0.60.51.50.90.50.71.20.5-0.50.6-0.6-0.50.70.9
Intermittent access day 1 total infusions2.63.04.52.11.81.72.11.7-1.71.7-1.7-1.31.71.6
Intermittent access day 15 total infusions4.24.87.42.52.32.22.72.0-2.02.1-2.1-1.82.12.0
Intermittent access terminal intake (last 3 days)6.06.69.52.92.82.63.12.3-2.42.4-2.4-2.32.52.4
Intermittent access total infusions5.86.59.33.02.72.63.02.4-2.42.4-2.4-2.12.42.4
Intermittent access day 1 locomotion0.90.91.91.41.10.91.30.9-0.90.9-0.9-0.50.90.6
Intermittent access day 15 total locomotion0.50.61.91.21.40.71.20.4-0.40.5-0.5-0.00.40.0
Intermittent access total locomotion1.11.22.81.71.61.11.31.0-1.01.0-1.0-0.50.90.6
Intermittent access standard deviation5.05.36.82.52.62.42.42.2-2.22.2-2.2-2.12.32.2
Left kidney weight0.92.54.20.91.21.60.71.7-1.71.7-1.7-2.11.71.9
Right kidney weight0.61.62.80.81.01.20.71.4-1.41.3-1.3-1.71.31.5
Cocaine induced anxiety0.80.91.70.60.60.90.31.1-1.11.1-1.1-1.31.01.1
Post-drug Anxiety0.00.00.10.2-0.20.1-0.10.3-0.30.2-0.2-0.20.20.3
Baseline Anxiety3.84.05.4-1.7-1.8-2.0-1.5-2.12.1-2.12.12.3-2.1-2.1
Tail length0.72.24.31.11.01.31.21.5-1.51.5-1.5-1.81.62.1
Length with tail0.72.63.71.31.31.51.31.7-1.71.7-1.7-1.71.71.9
Length without tail0.30.60.80.60.80.80.50.9-0.90.9-0.9-0.70.90.7
Times rat made contact with spout0.10.10.10.40.40.30.40.4-0.40.4-0.4-0.30.40.2
Lifetime Intake6.27.09.53.12.82.73.02.5-2.52.6-2.6-2.22.62.5
Liver weight, left0.81.32.30.50.61.10.61.3-1.31.2-1.2-1.51.21.5
Liver weight, right2.33.95.91.41.32.01.32.1-2.12.1-2.1-2.42.02.4
Locomotor activity0.00.00.20.40.40.20.10.1-0.10.1-0.10.10.1-0.1
Locomotor testing distance1.22.12.51.61.51.51.31.5-1.51.5-1.5-1.21.41.2
Locomotor testing rearing0.30.40.50.60.50.60.50.7-0.70.7-0.7-0.70.60.4
Locomotion in novel chamber0.30.31.41.20.80.40.80.4-0.40.4-0.4-0.10.40.0
Locomotion in novel chamber post-restriction1.01.21.8-1.3-0.9-1.0-1.1-1.11.1-1.11.11.2-1.1-1.1
Fecal boli incidents, locomotor time 15.25.78.9-2.5-3.0-2.5-2.4-2.42.4-2.42.42.0-2.3-1.9
Change in fecal boli incidents, locomotor task3.33.16.62.12.61.92.01.6-1.61.6-1.6-1.21.61.2
Time >=10cm from walls, locomotor time 10.00.00.2-0.3-0.5-0.10.1-0.10.1-0.10.1-0.2-0.00.1
Bouts of movement, locomotor time 10.20.20.8-0.4-0.9-0.5-0.2-0.30.3-0.40.40.3-0.4-0.1
Total resting periods, locomotor time 10.10.10.7-0.5-0.8-0.4-0.2-0.20.2-0.20.20.1-0.20.1
Rest time, locomotor task time 10.10.10.6-0.8-0.6-0.1-0.2-0.20.2-0.20.2-0.3-0.10.5
Distance moved, locomotor task time 11.51.72.31.31.51.31.01.4-1.41.4-1.4-1.21.31.1
Vertical activity count, locomotor time 10.10.10.20.40.50.2-0.00.3-0.30.2-0.20.20.1-0.0
Time >=10cm from walls, locomotor time 26.56.97.42.52.62.72.72.6-2.62.6-2.6-2.62.72.7
Bouts of movement, locomotor time 20.10.10.4-0.6-0.5-0.2-0.60.2-0.20.1-0.1-0.1-0.10.2
Total resting periods, locomotor time 20.10.10.3-0.5-0.4-0.1-0.50.2-0.20.1-0.1-0.10.00.2
Rest time, locomotor task time 22.12.42.7-1.6-1.5-1.5-1.4-1.61.6-1.61.61.5-1.5-1.4
Distance moved, locomotor task time 25.16.06.72.02.42.52.02.6-2.62.5-2.5-2.62.52.6
Vertical activity count, locomotor time 22.72.93.51.41.61.71.21.9-1.91.8-1.8-1.71.81.9
Light reinforcement 10.20.31.10.20.10.50.20.6-0.60.6-0.6-1.00.60.8
Light reinforcement 20.20.31.10.1-0.00.4-0.10.4-0.40.4-0.4-1.00.50.9
Bone: marrow area0.20.50.9-0.9-0.6-0.7-0.9-0.70.7-0.70.70.8-0.7-0.6
Bone: maximum diameter0.40.81.90.60.60.80.50.9-0.90.9-0.9-1.10.91.4
Bone: maximum force0.10.10.30.10.10.30.10.3-0.30.3-0.3-0.40.30.5
Bone: maximum moment0.00.00.1-0.4-0.3-0.2-0.4-0.10.1-0.10.10.0-0.10.1
Mean time between licks in bursts1.31.82.4-1.2-1.2-1.3-1.2-1.31.3-1.31.31.5-1.4-1.6
Mean num. licks in bursts0.00.00.0-0.2-0.2-0.0-0.20.1-0.10.1-0.1-0.10.10.2
Cd content in liver1.01.11.41.21.11.11.21.0-1.01.0-1.0-1.01.00.9
Co content in liver1.51.72.3-1.1-1.2-1.4-1.1-1.31.3-1.41.41.5-1.3-1.3
Cu content in liver0.20.30.3-0.5-0.5-0.5-0.5-0.50.5-0.50.50.4-0.5-0.4
Fe content in liver0.30.40.5-0.7-0.7-0.7-0.7-0.60.6-0.60.60.7-0.6-0.7
K content in liver2.72.63.2-1.8-1.7-1.7-1.8-1.51.5-1.61.61.5-1.6-1.5
Mg content in liver1.51.62.1-1.4-1.4-1.3-1.4-1.21.2-1.21.21.1-1.2-1.1
Mn content in liver1.41.62.4-1.6-1.5-1.3-1.6-1.21.2-1.21.20.9-1.2-1.0
Na content in liver0.00.00.1-0.3-0.3-0.0-0.30.2-0.20.1-0.1-0.20.10.3
Rb content in liver1.11.31.9-1.4-1.3-1.1-1.4-1.11.1-1.11.11.0-1.1-0.9
Se content in liver4.04.96.8-1.9-1.9-2.3-1.9-2.32.3-2.32.32.4-2.3-2.6
Sr content in liver0.10.10.1-0.3-0.3-0.3-0.3-0.20.2-0.20.20.2-0.2-0.1
Zn content in liver0.10.10.1-0.3-0.3-0.3-0.3-0.40.4-0.30.30.2-0.3-0.2
Bone: minimum diameter1.01.93.51.11.11.31.01.4-1.41.4-1.4-1.41.41.9
Time in familiar zone, hab. session 10.60.60.7-0.8-0.8-0.8-0.9-0.80.8-0.80.80.7-0.7-0.6
Time in novel zone, hab. session 11.31.31.91.11.41.21.11.1-1.11.1-1.1-1.01.11.0
Total zone transitions, hab. session 11.52.03.71.71.91.41.81.3-1.31.3-1.3-0.91.31.0
Total locomotion distance, hab. session 10.20.31.21.01.10.31.00.1-0.10.1-0.10.50.1-0.2
Locomotion velocity, hab. session 10.20.20.70.70.80.10.7-0.10.1-0.10.10.7-0.2-0.5
Time in familiar zone, hab. session 20.20.20.7-0.1-0.1-0.4-0.1-0.40.4-0.40.40.5-0.4-0.8
Time in novel zone, hab. session 20.50.51.50.30.30.70.30.7-0.70.7-0.7-1.00.81.2
Total zone transitions, hab. session 21.41.82.21.41.41.41.41.3-1.31.3-1.3-1.21.31.5
Total locomotion distance, hab. session 20.10.20.4-0.1-0.1-0.3-0.1-0.50.5-0.50.50.7-0.4-0.3
Locomotion velocity, hab. session 20.20.20.6-0.1-0.2-0.4-0.2-0.60.6-0.50.50.8-0.5-0.4
Novel to familiar place preference ratio0.70.81.00.90.80.90.81.0-1.00.9-0.9-0.90.80.5
Novelty place preference0.80.81.10.90.80.90.91.0-1.01.0-1.0-1.00.90.6
Time in novel zone, NPP test0.70.70.90.80.70.80.71.0-1.00.9-0.9-0.90.80.5
Total zone transitions, NPP test0.81.21.9-0.7-0.7-1.1-0.7-1.21.2-1.21.21.4-1.1-1.2
Total locomotion distance, NPP test1.21.62.9-0.8-0.8-1.2-0.8-1.41.4-1.41.41.7-1.3-1.3
Locomotion velocity, NPP test1.11.53.0-0.7-0.7-1.2-0.7-1.41.4-1.41.31.7-1.3-1.3
Intraocular pressure0.10.10.20.20.2-0.00.2-0.30.3-0.30.30.3-0.3-0.4
Delta distance traveled before/after self-admin0.10.10.3-0.2-0.5-0.10.1-0.00.0-0.00.0-0.40.00.4
Delta ambulatory time before/after self-admin0.10.10.4-0.1-0.30.20.10.3-0.30.2-0.2-0.60.30.6
Parametrial fat weight0.71.32.61.31.11.11.61.0-1.01.1-1.1-1.01.11.0
Pavlov. Cond. lever latency0.40.50.8-0.9-0.8-0.7-0.8-0.70.7-0.70.70.6-0.8-0.5
Pavlov. Cond. magazine entry latency1.31.72.61.01.01.31.01.4-1.41.4-1.3-1.61.41.4
Pavlov. Cond. change in total contacts0.20.20.3-0.4-0.4-0.4-0.5-0.40.4-0.40.40.4-0.4-0.5
Pavlov. Cond. index score0.30.40.50.50.50.60.50.6-0.60.6-0.6-0.70.70.5
Pavlov. Cond. latency score0.30.40.50.50.50.60.50.7-0.70.7-0.6-0.70.70.5
Pavlov. Cond. lever contacts0.40.50.60.70.70.70.60.8-0.80.8-0.8-0.80.80.6
Pavlov. Cond. magazine entry number1.21.52.2-1.0-0.9-1.2-0.9-1.31.3-1.31.31.5-1.3-1.3
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.10.1-0.2-0.1-0.20.2-0.20.20.6-0.3-0.2
Pavlov. Cond. lever-magazine prob. diff.0.20.20.30.50.40.50.50.5-0.50.5-0.5-0.50.50.4
Pavlov. Cond. response bias1.21.42.01.00.91.20.91.3-1.31.2-1.2-1.41.31.3
Pavlov. Cond. lever latency2.53.43.5-1.9-1.9-1.9-1.9-1.81.8-1.91.91.9-1.8-1.7
Pavlov. Cond. magazine entry latency0.80.91.21.01.01.01.10.9-0.90.9-0.9-0.90.90.7
Pavlov. Cond. change in total contacts1.11.51.81.31.31.31.31.2-1.21.2-1.2-1.21.21.0
Pavlov. Cond. index score2.02.63.11.71.71.61.71.6-1.61.6-1.6-1.51.51.3
Pavlov. Cond. latency score2.32.93.71.91.91.71.91.7-1.71.7-1.7-1.61.61.4
Pavlov. Cond. lever contacts2.83.84.32.12.12.02.11.9-1.91.9-1.9-1.91.91.7
Pavlov. Cond. magazine entry number0.50.60.7-0.8-0.8-0.8-0.8-0.80.8-0.80.80.7-0.7-0.5
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.2-0.2-0.2-0.20.0-0.0-0.00.00.0-0.0-0.0
Pavlov. Cond. lever-magazine prob. diff.1.82.32.71.61.61.61.61.5-1.51.5-1.5-1.51.51.3
Pavlov. Cond. response bias2.33.23.51.71.71.81.71.8-1.81.8-1.8-1.91.71.6
Time in closed arm before self-admin3.13.54.21.81.61.82.01.9-1.91.9-1.9-1.81.92.1
Time in closed arm after self-admin1.01.11.40.80.81.00.91.1-1.11.1-1.1-1.11.01.2
Time in open arm before self-admin2.42.63.3-1.4-1.4-1.6-1.5-1.61.6-1.61.61.8-1.6-1.8
Time in open arm after self-admin4.04.46.4-1.5-1.5-1.9-1.7-2.32.3-2.22.22.5-2.2-2.3
Bone: periosteal estimation0.00.10.3-0.3-0.2-0.0-0.30.1-0.10.1-0.1-0.20.10.5
Bone: periosteal perimeter1.11.93.21.31.31.31.31.3-1.31.3-1.3-1.41.41.8
Bone: post-yield work0.10.10.50.10.0-0.10.0-0.30.3-0.30.30.3-0.3-0.7
Progressive ratio test 1 active lever presses3.53.74.82.21.92.01.91.9-1.91.9-1.9-1.71.92.0
Progressive ratio test 1 breakpoint3.43.64.62.11.81.91.91.8-1.81.9-1.9-1.81.92.0
Progressive ratio test 1 inactive lever presses2.22.43.01.41.31.51.21.6-1.61.6-1.6-1.61.61.7
Progressive ratio test 2 active lever presses2.72.93.51.81.71.71.91.7-1.71.7-1.7-1.61.71.7
Progressive ratio test 2 breakpoint3.43.94.62.11.92.02.11.9-1.91.9-1.9-1.91.92.0
Progressive ratio test 2 inactive lever presses3.94.54.92.12.02.11.82.2-2.22.2-2.2-2.12.22.2
Incentive Sensitization - Responses1.31.42.01.11.01.11.41.2-1.21.2-1.2-1.11.21.1
Incentive Sensitization - Breakpoint1.11.11.61.01.01.01.31.0-1.01.0-1.0-1.01.01.0
Sum of active levers in priming session hrs 5-60.50.41.3-1.1-1.1-0.5-1.1-0.40.4-0.40.4-0.1-0.40.0
Progressive ratio0.50.61.10.50.70.90.20.8-0.80.8-0.8-1.00.81.0
Food seeking constrained by brief footshock0.70.91.20.91.11.01.00.9-0.91.0-1.0-1.01.00.7
Seeking ratio, punishment vs. effort0.50.61.2-0.4-0.4-0.8-0.1-0.80.8-0.80.81.0-0.8-1.1
Retroperitoneal fat weight8.728.632.35.45.75.45.05.6-5.65.5-5.5-5.15.34.8
Reaction time number correct0.00.10.20.50.20.20.40.2-0.20.2-0.2-0.20.20.1
Reaction time mean minus median0.10.20.40.20.30.50.20.3-0.30.4-0.4-0.60.40.6
Reaction time mean minus median AUC0.10.20.40.10.40.50.30.4-0.40.4-0.4-0.50.40.6
Reaction time num false alarms1.62.22.7-1.4-1.2-1.4-1.5-1.61.6-1.51.51.5-1.5-1.6
Reaction time num false alarms AUC2.02.83.1-1.6-1.4-1.6-1.8-1.71.7-1.71.71.7-1.7-1.8
Reaction time trials correct on left0.00.10.20.50.20.20.40.2-0.20.2-0.2-0.20.20.1
Reaction time trials on left0.00.00.10.30.10.10.30.1-0.10.1-0.1-0.10.20.0
Reaction time mean0.40.50.90.60.40.70.60.8-0.70.7-0.7-0.90.71.0
Reaction time mean AUC0.70.91.40.70.60.90.71.0-1.00.9-0.9-1.10.91.2
Median of all reaction times0.71.01.60.90.61.00.91.0-1.01.0-1.0-1.11.01.3
Reaction time omissions1.01.41.9-1.4-1.2-1.2-1.2-1.11.1-1.21.21.0-1.2-1.1
Reaction time false alarm rate2.94.14.6-2.0-1.7-2.0-2.1-2.12.1-2.02.02.0-2.0-2.1
Reaction time premature initiation rate0.10.10.3-0.0-0.6-0.3-0.3-0.20.2-0.20.2-0.1-0.10.2
Reaction time premature initiations0.00.00.20.2-0.4-0.2-0.1-0.10.1-0.10.1-0.1-0.00.2
Std. dev. reaction times0.10.10.3-0.00.10.3-0.00.2-0.20.2-0.2-0.50.30.5
Reaction time trials completed0.00.00.10.30.10.10.30.1-0.10.1-0.1-0.10.20.0
Reaction time trials AUC0.10.10.30.60.30.30.50.3-0.30.3-0.3-0.30.40.2
Run reversals in cocaine runway, females0.40.40.70.30.30.50.40.8-0.80.8-0.8-0.80.70.7
Run reversals in cocaine runway, males4.54.36.6-2.4-2.3-2.2-2.6-1.81.8-1.91.91.7-2.1-2.1
Latency to leave start box in cocaine runway0.40.51.1-0.7-0.6-0.6-1.1-0.60.6-0.60.60.7-0.6-0.7
Latency to leave start box in cocaine runway, F0.40.41.0-0.6-0.5-0.6-1.0-0.60.6-0.60.60.6-0.6-0.8
Latency to leave start box in cocaine runway, M0.10.10.2-0.4-0.5-0.3-0.4-0.20.3-0.30.30.2-0.3-0.1
Std. dev. time between licks in bursts0.10.10.3-0.5-0.5-0.3-0.5-0.30.3-0.30.30.2-0.3-0.2
Total sessions with >9 infusions2.52.83.92.01.51.61.81.7-1.71.7-1.7-1.51.61.6
Short access day 1 total inactive lever presses0.60.71.11.01.00.80.80.8-0.80.8-0.8-0.50.80.5
Short access day 10 total inactive lever presses0.60.61.40.00.20.7-0.30.9-0.90.9-0.9-1.20.80.9
Short access day 1 total infusions9.29.811.63.43.13.23.13.1-3.13.1-3.1-2.93.23.1
Short access day 10 total infusions2.73.05.62.42.21.72.21.5-1.51.6-1.6-1.11.61.3
Short access total infusions5.15.78.32.92.52.42.72.3-2.32.3-2.3-2.12.32.2
Short access day 1 locomotion2.62.85.62.42.11.81.81.4-1.41.5-1.5-1.31.61.3
Short access day 10 total locomotion2.02.33.51.91.91.61.31.4-1.41.5-1.5-1.21.41.3
Short access total locomotion2.32.44.82.21.91.61.61.4-1.41.4-1.4-1.21.41.3
One hour access (0.3 mA shock)2.63.13.51.91.81.71.81.7-1.71.7-1.7-1.71.71.7
Compulsive drug intake1.71.72.6-1.4-1.6-1.3-1.6-1.21.2-1.31.31.2-1.2-1.0
One hour access (shock baseline)5.66.58.42.82.82.62.92.4-2.42.5-2.4-2.32.42.3
Social response proportion3.33.65.2-2.1-2.3-2.0-2.1-1.81.8-1.81.81.6-1.8-1.6
Social responses0.10.20.60.30.10.30.10.4-0.40.4-0.4-0.80.40.6
Social time2.43.23.6-1.3-1.8-1.9-1.5-1.91.9-1.91.91.9-1.8-1.9
Soleus weight1.64.85.7-2.3-2.4-2.3-2.3-2.02.1-2.12.12.1-2.2-2.2
Bone: stiffness0.50.81.20.70.70.90.70.9-0.91.0-1.0-1.11.01.0
Tibialis anterior weight2.38.010.1-3.1-3.2-2.9-3.1-2.72.7-2.82.82.5-2.8-2.6
Time to tail flick, vehicle, before self-admin2.02.03.51.71.91.51.61.3-1.31.3-1.3-1.11.41.1
Time to tail flick, vehicle, after self-admin4.04.25.72.42.42.12.31.9-1.92.0-2.0-1.72.01.8
Time to tail flick, test, before self-admin1.21.21.81.21.31.30.91.0-1.01.0-1.0-1.01.11.1
Time to tail flick, test, after self-admin1.61.63.01.61.71.31.31.2-1.21.2-1.2-0.91.20.8
Delta time to tail flick, vehicle, before/after SA0.10.10.20.40.30.30.40.4-0.40.4-0.4-0.30.30.3
Delta time to tail flick, test, before/after SA0.10.10.30.30.1-0.20.4-0.20.2-0.20.20.4-0.2-0.6
Tibia length0.10.20.5-0.7-0.6-0.1-0.70.1-0.10.0-0.0-0.40.10.6
Ambulatory time before self-admin0.60.61.10.40.60.70.90.8-0.80.8-0.8-1.00.81.0
Ambulatory time after self-admin2.32.54.80.90.91.61.21.6-1.61.6-1.5-2.21.62.2
Bone: tissue strength0.30.30.4-0.4-0.2-0.4-0.4-0.60.6-0.60.60.6-0.6-0.6
Total heroin consumption0.91.02.1-1.1-1.4-1.2-1.1-0.90.9-0.90.90.7-0.9-0.8
Bone: trabecular number0.50.71.11.10.90.80.90.9-0.90.8-0.8-0.70.80.5
Bone: trabecular spacing0.10.10.20.30.40.40.40.3-0.30.4-0.4-0.50.40.4
Bone: trabecular thickness0.20.30.30.50.50.50.50.6-0.60.6-0.6-0.50.50.4
Bone: trabecular tissue density1.21.82.2-1.5-1.4-1.3-1.4-1.21.2-1.31.31.2-1.3-1.5
Water consumed over 24 hours0.30.40.50.50.50.60.50.7-0.70.7-0.7-0.70.70.7
Number of responses in last shaping day2.42.52.91.71.31.51.51.6-1.61.6-1.6-1.71.61.6