Hub : Genes

C10h17orf75

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression C10h17orf75 0.05 0.04 1.0e-05 0.03 0.03 0.03 0.03 8.5e-04 3.9e-04 3.5e-04 4.8e-04
2 OFC gene expression C10h17orf75 0.17 0.12 3.1e-04 0.13 0.16 0.16 0.13 4.8e-04 1.5e-04 1.6e-04 5.5e-04
3 NAcc mRNA stability C10h17orf75 0.01 0.01 2.7e-03 0.01 0.01 0.01 0.01 4.3e-03 3.4e-03 8.4e-03 8.8e-03
4 IC gene expression C10h17orf75 0.08 0.05 9.2e-05 0.04 0.08 0.05 0.04 7.7e-03 4.0e-04 4.3e-03 9.3e-03
5 NAcc gene expression C10h17orf75 0.19 0.02 0.0e+00 0.14 0.15 0.14 0.15 9.0e-21 1.5e-21 7.3e-21 1.3e-21
6 IL gene expression C10h17orf75 0.22 0.14 2.2e-05 0.13 0.23 0.19 0.21 4.2e-04 3.7e-06 2.9e-05 1.0e-05
7 pVTA gene expression C10h17orf75 0.24 0 0.0e+00 0.21 0.22 0.21 0.22 6.7e-17 2.0e-17 5.8e-17 3.0e-17
8 PL gene expression C10h17orf75 0.2 0.1 0.0e+00 0.19 0.21 0.21 0.21 1.5e-20 1.1e-22 8.2e-23 6.5e-23
9 Brain gene expression C10h17orf75 0.23 0.11 0.0e+00 0.29 0.3 0.29 0.3 2.4e-27 2.5e-28 7.9e-27 5.7e-28
10 Adipose gene expression C10h17orf75 0.02 0.02 6.5e-03 0.01 0 0.01 0 1.0e-02 1.1e-01 6.9e-02 8.5e-02
11 BLA gene expression C10h17orf75 0.19 0.1 8.9e-09 0.13 0.14 0.17 0.16 1.8e-07 6.9e-08 3.8e-09 4.9e-09
12 RMTg gene expression C10h17orf75 0.43 0.19 7.0e-04 0.04 0.13 0.1 0.08 3.4e-02 3.2e-04 1.7e-03 4.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density2.34.04.72.12.22.22.12.12.12.12.12.02.01.61.1
Area under the delay curve0.00.00.1-0.1-0.0-0.0-0.00.1-0.0-0.0-0.1-0.0-0.3-0.2-0.1
BMI with tail1.13.77.52.72.22.22.11.51.81.81.61.71.82.20.3
BMI without tail0.61.83.60.71.01.11.21.21.31.31.41.41.71.51.9
Body weight2.29.611.32.53.23.23.23.03.23.23.33.23.23.42.5
Weight adjusted by age1.01.52.3-1.5-1.4-1.4-1.4-1.2-1.2-1.2-1.1-1.2-1.2-1.1-0.5
Bone surface0.51.01.31.11.11.11.10.91.11.11.11.01.00.70.4
Bone volume1.12.02.51.61.51.51.51.41.51.51.51.41.41.10.8
Breakpoint value in progressive ratio session0.60.73.6-0.60.20.20.40.80.60.71.10.80.90.21.9
Number of licking bursts0.20.31.71.20.10.10.0-0.1-0.1-0.2-0.5-0.4-0.5-0.4-1.3
Context. condit. distance diff. score0.30.41.01.00.70.70.60.70.60.60.30.50.40.6-0.1
Locomotion velocity, session 10.60.71.00.91.00.90.90.60.90.90.90.80.80.70.2
Locomotion distance, session 10.00.00.2-0.4-0.1-0.1-0.1-0.2-0.1-0.1-0.1-0.1-0.0-0.1-0.1
Locomotion velocity, session 20.00.00.1-0.2-0.1-0.1-0.1-0.1-0.0-0.00.2-0.00.1-0.20.1
Locomotion distance, session 20.50.71.10.30.70.80.80.70.80.81.00.91.00.60.9
Locomotion velocity, session 32.02.32.6-1.2-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.4-1.4-1.2
Locomotion distance, session 30.60.61.0-1.0-0.8-0.8-0.9-1.0-0.9-0.8-0.7-0.8-0.7-0.4-0.5
Stereotopy head waving bouts, day 30.10.20.3-0.3-0.6-0.6-0.5-0.4-0.5-0.4-0.3-0.4-0.3-0.1-0.0
Stereotopy head waving duration, day 30.20.30.5-0.2-0.7-0.7-0.6-0.3-0.5-0.5-0.5-0.6-0.5-0.5-0.2
Locomotion velocity, session 70.40.41.41.20.60.60.60.50.60.60.60.50.80.5-0.0
Locomotion distance, session 70.20.30.60.80.50.60.50.40.50.50.50.50.60.30.1
Stereotopy head waving bouts, day 70.30.31.9-0.9-0.1-0.10.00.30.20.30.60.40.50.31.4
Stereotopy head waving duration, day 70.20.21.1-1.0-0.3-0.3-0.20.1-0.00.00.40.20.3-0.01.1
Locomotion velocity, session 80.00.00.30.30.20.10.0-0.1-0.0-0.0-0.1-0.1-0.1-0.1-0.6
Locomotion distance, session 80.10.20.30.40.50.50.50.60.40.40.30.40.40.40.2
Degree of sensitization distance1.92.02.51.41.41.41.41.61.51.51.51.51.50.91.2
Degree of sensitization stereotypy0.50.51.7-0.40.40.40.50.60.70.70.90.80.80.61.3
Conditioned locomotion2.22.52.8-1.6-1.6-1.6-1.6-1.6-1.7-1.7-1.5-1.7-1.6-1.6-1.3
Cocaine response after cond. corrected1.82.22.61.41.61.61.61.41.51.51.61.51.61.41.0
Cocaine response after cond. not corrected2.53.03.51.21.71.71.81.91.81.71.81.81.91.71.6
Cocaine response before conditioning0.20.21.1-0.5-0.00.00.10.60.30.30.20.40.30.31.1
Saline control response0.20.31.4-1.2-0.7-0.6-0.5-0.2-0.4-0.4-0.3-0.3-0.3-0.60.5
Bone: connectivity density2.43.74.72.02.22.12.12.02.12.02.02.01.91.40.9
Bone: cortical apparent density0.00.00.10.1-0.1-0.1-0.10.1-0.0-0.0-0.1-0.00.00.10.2
Bone: cortical area1.01.62.3-1.0-1.5-1.5-1.4-1.2-1.3-1.3-1.2-1.3-1.2-1.4-0.6
Bone: cortical porosity0.10.10.1-0.0-0.3-0.3-0.3-0.1-0.3-0.3-0.3-0.3-0.3-0.2-0.1
Bone: cortical porosity0.00.00.20.4-0.1-0.0-0.00.1-0.1-0.1-0.1-0.1-0.10.0-0.2
Bone: cortical thickness1.82.94.7-1.6-2.2-2.1-2.0-1.4-1.8-1.8-1.6-1.7-1.6-1.8-0.4
Bone: cortical thickness0.10.10.5-0.5-0.5-0.4-0.30.0-0.2-0.10.1-0.10.2-0.30.7
Bone: cortical tissue density0.00.10.10.30.10.10.20.40.20.20.10.20.20.40.4
Condit. Reinf. active minus inactive responses0.10.10.50.70.10.10.1-0.1-0.00.00.1-0.00.10.4-0.4
Condit. Reinf. active-inactive response ratio0.10.10.2-0.3-0.4-0.4-0.4-0.5-0.4-0.3-0.3-0.3-0.20.3-0.0
Condit. Reinf. active responses0.10.20.90.90.30.40.30.20.20.30.30.20.30.3-0.3
Condit. Reinf. inactive responses0.10.10.50.70.40.40.30.20.20.20.20.10.1-0.4-0.4
Incentive salience index mean0.00.00.20.3-0.0-0.0-0.0-0.2-0.1-0.00.2-0.00.10.4-0.1
Condit. Reinf. lever presses0.10.10.40.10.20.20.30.10.30.30.60.40.50.50.6
Condit. Reinf. active minus inactive responses0.10.10.30.2-0.2-0.2-0.2-0.1-0.2-0.2-0.5-0.3-0.2-0.4-0.4
Condit. Reinf. active-inactive response ratio0.10.10.2-0.2-0.3-0.3-0.3-0.1-0.2-0.2-0.4-0.3-0.3-0.4-0.0
Condit. Reinf. active responses0.10.20.50.0-0.4-0.4-0.4-0.3-0.4-0.4-0.7-0.5-0.4-0.5-0.5
Condit. Reinf. inactive responses0.10.10.20.1-0.3-0.3-0.3-0.3-0.3-0.3-0.4-0.3-0.2-0.2-0.4
Condit. Reinf. lever presses0.40.61.0-0.5-1.0-0.9-0.9-0.7-0.8-0.8-1.0-0.8-0.7-0.7-0.5
Condit. Reinf. lever reinforcers received0.30.40.7-0.3-0.6-0.6-0.6-0.5-0.6-0.6-0.9-0.7-0.5-0.6-0.5
Conditioned reinforcement - actives0.40.72.0-1.4-1.0-1.0-0.9-0.8-0.8-0.8-0.6-0.7-0.5-0.80.4
Conditioned reinforcement - inactives2.13.14.8-2.2-2.2-2.1-2.0-1.7-1.8-1.7-1.5-1.6-1.5-1.7-0.2
Conditioned locomotion2.33.06.0-2.4-2.2-2.1-2.0-2.0-1.8-1.7-1.4-1.6-1.2-0.90.3
Patch foraging indifference point 0 sec0.00.00.10.3-0.00.00.10.20.10.20.20.20.10.40.3
Patch foraging indifference point AUC1.72.42.8-1.4-1.7-1.7-1.7-1.6-1.6-1.6-1.6-1.6-1.6-1.3-1.0
Delay disc. indifference point, 0s delay0.60.61.0-1.0-0.9-0.9-0.9-0.8-0.8-0.8-0.7-0.7-0.7-0.8-0.1
Delay disc. indifference point, 16s delay0.10.20.30.50.50.50.50.60.40.40.10.3-0.00.1-0.1
Delay disc. indifference point, 2s delay0.60.71.0-0.4-0.8-0.8-0.8-0.6-0.8-0.8-0.9-0.9-1.0-0.9-0.9
Delay disc. indifference point, 24s delay0.20.20.30.50.40.50.50.50.50.50.50.40.40.50.2
Delay disc. indifference point, 4s delay1.21.22.50.91.11.11.11.61.31.21.11.20.90.81.1
Delay disc. indifference point, 8s delay0.10.10.3-0.20.10.10.20.30.30.30.20.30.10.30.5
Indifference point function ln k5.59.615.74.03.63.53.42.73.13.12.93.03.03.10.7
Indifference point function log k5.59.615.74.03.63.53.42.73.13.12.93.03.03.10.7
Patch foraging total patch changes 0 sec0.00.00.20.1-0.2-0.2-0.10.10.00.10.10.10.00.20.4
Patch foraging total patch changes 12 sec0.60.71.8-1.3-1.2-1.1-1.0-0.7-0.8-0.7-0.5-0.6-0.6-0.60.5
Patch foraging total patch changes 18 sec1.11.63.6-1.9-1.7-1.6-1.5-1.0-1.2-1.2-1.1-1.1-1.0-1.20.5
Patch foraging total patch changes 24 sec0.91.52.1-1.2-1.4-1.4-1.4-1.4-1.3-1.2-1.1-1.2-1.2-1.0-0.5
Patch foraging total patch changes 6 sec2.13.14.3-1.8-2.1-2.0-2.0-1.8-1.8-1.8-1.7-1.8-1.8-1.6-0.7
Patch foraging time to switch 0 sec0.40.84.6-2.1-0.9-0.9-0.7-0.1-0.5-0.5-0.3-0.3-0.6-1.01.0
Patch foraging water rate 0 sec0.20.41.61.2-0.1-0.1-0.3-0.8-0.4-0.4-0.5-0.5-0.30.1-1.3
Patch foraging water rate 12 sec1.02.04.62.11.51.51.41.01.41.41.41.31.41.40.3
Patch foraging water rate 18 sec2.33.65.02.22.12.12.01.51.91.91.91.91.92.10.7
Patch foraging water rate 24 sec0.91.33.61.91.21.21.10.71.01.01.00.91.11.30.1
Patch foraging water rate 6 sec0.30.53.11.70.60.60.4-0.10.20.30.20.10.20.5-1.0
Seeking ratio, delayed vs. immediate footshock0.10.10.50.0-0.2-0.1-0.10.2-0.1-0.1-0.0-0.10.00.70.6
Distance traveled before self-admin1.72.33.1-1.5-1.8-1.8-1.7-1.4-1.5-1.5-1.4-1.5-1.6-1.3-0.7
Distance traveled after self-admin0.40.52.1-1.5-0.8-0.7-0.6-0.0-0.3-0.3-0.0-0.2-0.10.11.4
Extensor digitorum longus weight0.10.20.60.40.60.60.50.20.40.40.50.50.40.80.1
Bone: elastic displacement0.10.10.70.7-0.00.0-0.0-0.3-0.2-0.2-0.3-0.3-0.1-0.3-0.8
Bone: elastic work3.54.65.4-1.5-2.3-2.2-2.2-2.3-2.3-2.2-2.2-2.3-2.0-2.2-1.7
Bone: endosteal estimation0.10.30.6-0.3-0.3-0.4-0.4-0.7-0.5-0.5-0.5-0.5-0.6-0.7-0.8
Bone: endosteal perimeter0.20.40.80.90.80.80.70.30.60.60.50.50.40.5-0.3
Epididymis fat weight7.224.628.83.34.74.74.95.45.25.25.35.35.15.25.0
Delta time in closed arm before/after self-admin0.20.21.01.00.40.40.40.40.30.2-0.10.1-0.00.3-0.3
Delta time in open arm before/after self-admin0.70.71.4-0.10.70.70.80.80.80.80.90.91.00.91.2
Diff in mean of infusions in LGA sessions0.10.10.4-0.6-0.3-0.3-0.3-0.2-0.2-0.2-0.1-0.1-0.2-0.60.3
Delay discount exponential model param0.00.00.1-0.2-0.2-0.2-0.2-0.3-0.2-0.1-0.0-0.10.10.00.1
Extinction: sum of active levers before priming0.20.20.9-0.8-0.3-0.3-0.3-0.2-0.2-0.2-0.1-0.2-0.3-1.00.1
Active lever presses in extinction session 60.90.92.9-1.7-1.1-1.1-1.1-0.9-0.8-0.8-0.5-0.7-0.8-0.80.4
Bone: final force0.50.81.8-1.3-1.2-1.1-1.0-0.8-0.9-0.8-0.6-0.7-0.5-0.80.4
Bone: final moment0.40.71.3-1.1-1.1-1.0-1.0-0.9-0.9-0.8-0.5-0.7-0.5-0.80.2
Food consumed during 24 hour testing period0.30.51.90.3-0.4-0.4-0.5-0.8-0.6-0.6-0.7-0.7-0.7-0.6-1.4
Glucose0.30.51.0-0.2-0.8-0.8-0.7-0.6-0.7-0.7-0.7-0.8-0.5-1.0-0.3
Heart weight1.01.52.10.81.21.21.31.11.31.31.51.41.41.01.2
Delay discount hyperbolic model param0.00.00.0-0.0-0.0-0.0-0.0-0.2-0.1-0.00.0-0.00.20.10.1
Intermittent access intake day 1-15 change0.10.20.3-0.2-0.4-0.4-0.4-0.5-0.5-0.4-0.6-0.4-0.4-0.2-0.3
Intermittent access intake escalation0.10.10.3-0.2-0.3-0.3-0.3-0.5-0.5-0.4-0.6-0.4-0.3-0.2-0.3
Intermittent access intake escalation 20.10.10.3-0.2-0.5-0.4-0.4-0.4-0.4-0.4-0.6-0.4-0.2-0.1-0.0
Intermitt. access day 1 inactive lever presses0.31.01.4-1.0-1.1-1.1-1.1-1.2-1.1-1.1-1.1-1.1-0.8-0.8-0.7
Intermitt. access day 15 inactive lever presses3.77.610.8-3.0-2.9-2.9-2.9-2.4-2.7-2.8-2.6-2.7-2.8-3.3-1.4
Intermitt. access escalation Index0.20.30.70.50.70.60.60.40.60.60.40.60.40.80.1
Intermittent access day 1 total infusions1.01.75.3-2.3-1.5-1.5-1.4-1.1-1.1-1.1-0.8-1.0-0.9-1.20.5
Intermittent access day 15 total infusions1.21.85.0-2.2-1.6-1.6-1.5-1.3-1.3-1.2-1.0-1.1-0.9-1.00.4
Intermittent access terminal intake (last 3 days)0.70.93.7-1.9-1.1-1.1-1.0-0.7-0.7-0.6-0.5-0.5-0.3-0.41.0
Intermittent access total infusions1.01.24.0-2.0-1.3-1.3-1.2-1.1-1.0-1.0-0.8-0.8-0.7-0.80.5
Intermittent access day 1 locomotion2.43.07.1-2.7-2.1-2.1-2.0-1.8-1.7-1.6-1.3-1.5-1.3-1.30.2
Intermittent access day 15 total locomotion1.42.54.2-2.1-1.9-1.9-1.8-1.8-1.7-1.6-1.3-1.5-1.3-0.9-0.2
Intermittent access total locomotion1.61.94.1-2.0-1.7-1.6-1.6-1.7-1.4-1.3-1.0-1.2-0.9-0.70.1
Intermittent access standard deviation1.53.05.3-2.0-1.9-1.9-1.8-1.5-1.7-1.7-1.6-1.6-1.7-2.3-0.6
Left kidney weight0.10.61.6-0.10.50.50.60.60.70.70.80.80.81.11.3
Right kidney weight0.00.20.60.10.10.10.20.20.30.30.50.40.40.80.8
Cocaine induced anxiety0.20.30.50.50.50.50.60.70.60.60.50.60.50.30.6
Post-drug Anxiety0.50.52.5-0.20.20.30.41.00.70.70.80.80.50.31.6
Baseline Anxiety0.60.71.0-0.8-1.0-1.0-0.9-0.6-0.8-0.8-0.7-0.8-0.9-1.0-0.2
Tail length0.31.47.3-0.80.20.30.51.10.91.01.21.21.30.62.7
Length with tail0.93.78.40.11.41.51.62.12.02.02.32.22.01.62.9
Length without tail0.92.83.61.21.81.71.71.91.81.81.91.81.41.51.2
Times rat made contact with spout0.40.51.11.10.70.70.70.50.60.60.60.60.80.80.1
Lifetime Intake1.61.96.4-2.5-1.6-1.6-1.5-1.4-1.3-1.2-1.0-1.1-1.0-1.10.4
Liver weight, left2.54.17.00.61.81.81.92.22.12.12.32.32.11.72.6
Liver weight, right3.25.513.10.41.71.82.02.82.42.42.52.62.42.33.6
Locomotor activity0.81.37.2-0.50.20.30.51.30.90.91.11.11.31.02.7
Locomotor testing distance0.61.28.6-1.4-0.6-0.4-0.11.00.40.40.70.60.80.22.9
Locomotor testing rearing0.20.52.9-1.2-0.7-0.6-0.30.6-0.1-0.10.00.10.1-0.31.7
Locomotion in novel chamber0.60.81.5-0.4-0.6-0.7-0.7-1.0-0.9-0.9-1.0-1.0-1.1-0.6-1.2
Locomotion in novel chamber post-restriction2.43.95.72.42.12.12.11.92.02.02.01.91.92.11.0
Fecal boli incidents, locomotor time 10.40.61.51.20.80.80.80.60.70.70.50.60.91.00.1
Change in fecal boli incidents, locomotor task0.40.40.70.80.80.80.80.50.70.70.60.60.30.7-0.1
Time >=10cm from walls, locomotor time 10.10.10.3-0.2-0.3-0.2-0.2-0.4-0.3-0.2-0.1-0.20.20.60.2
Bouts of movement, locomotor time 12.42.75.4-0.5-1.3-1.3-1.5-1.9-1.7-1.7-1.7-1.8-1.9-1.5-2.3
Total resting periods, locomotor time 12.52.85.8-0.5-1.3-1.3-1.5-1.9-1.7-1.7-1.7-1.8-2.0-1.6-2.4
Rest time, locomotor task time 10.50.61.70.1-0.5-0.5-0.6-0.7-0.7-0.8-0.8-0.8-0.7-1.2-1.3
Distance moved, locomotor task time 10.30.52.3-0.60.20.20.30.50.50.60.80.70.70.61.5
Vertical activity count, locomotor time 11.22.94.01.21.61.71.71.71.81.81.71.81.82.01.6
Time >=10cm from walls, locomotor time 20.20.31.80.30.30.40.4-0.10.10.20.30.30.81.30.3
Bouts of movement, locomotor time 20.20.30.8-0.4-0.5-0.5-0.5-0.4-0.5-0.5-0.7-0.6-0.6-0.9-0.4
Total resting periods, locomotor time 20.20.40.9-0.4-0.5-0.5-0.5-0.5-0.5-0.6-0.7-0.6-0.6-0.9-0.6
Rest time, locomotor task time 20.91.22.0-0.0-1.0-1.0-1.0-0.9-1.1-1.1-1.2-1.2-1.2-1.4-1.3
Distance moved, locomotor task time 20.10.10.5-0.60.20.20.20.20.30.30.40.40.20.20.7
Vertical activity count, locomotor time 20.70.92.0-0.10.80.80.91.11.01.01.01.11.01.01.4
Light reinforcement 10.30.83.4-0.30.40.40.61.00.80.81.11.01.00.51.9
Light reinforcement 20.10.21.1-0.7-0.2-0.2-0.10.20.10.10.20.20.10.11.0
Bone: marrow area0.20.30.6-0.4-0.4-0.4-0.5-0.7-0.5-0.5-0.6-0.5-0.6-0.8-0.8
Bone: maximum diameter0.20.41.40.4-0.3-0.4-0.5-0.8-0.6-0.6-0.7-0.7-0.7-0.5-1.2
Bone: maximum force1.12.04.0-2.0-1.8-1.7-1.6-1.2-1.4-1.4-1.2-1.3-1.1-1.50.3
Bone: maximum moment1.11.93.3-1.8-1.7-1.6-1.5-1.3-1.4-1.3-1.2-1.3-1.1-1.40.0
Mean time between licks in bursts0.00.10.3-0.6-0.4-0.4-0.3-0.0-0.3-0.3-0.2-0.2-0.2-0.40.3
Mean num. licks in bursts0.40.62.4-0.80.20.20.30.40.50.50.90.70.90.81.5
Cd content in liver0.00.00.1-0.30.10.10.1-0.00.10.00.10.1-0.1-0.10.1
Co content in liver0.20.20.5-0.3-0.4-0.4-0.4-0.5-0.4-0.4-0.5-0.4-0.5-0.7-0.4
Cu content in liver3.23.85.1-1.6-1.9-1.9-2.0-1.9-1.9-2.0-2.0-2.0-2.3-2.2-1.8
Fe content in liver0.60.71.10.20.90.90.91.01.00.91.01.00.90.40.9
K content in liver0.20.20.90.90.50.40.30.00.20.1-0.10.0-0.20.3-0.9
Mg content in liver0.30.31.20.1-0.1-0.2-0.3-0.5-0.4-0.5-0.6-0.5-0.6-0.4-1.1
Mn content in liver0.70.71.4-0.3-0.6-0.7-0.7-0.8-0.8-0.8-1.0-0.9-1.1-1.0-1.2
Na content in liver1.11.21.70.71.21.21.21.21.11.11.11.10.91.30.7
Rb content in liver0.10.10.8-0.3-0.2-0.2-0.2-0.1-0.2-0.2-0.2-0.3-0.3-0.9-0.3
Se content in liver3.23.87.5-2.7-2.1-2.1-2.0-1.7-1.9-1.9-1.8-1.8-2.0-2.2-0.7
Sr content in liver0.00.00.0-0.0-0.0-0.0-0.0-0.00.0-0.00.1-0.0-0.0-0.0-0.0
Zn content in liver0.20.20.30.10.40.40.50.50.50.50.50.50.40.20.5
Bone: minimum diameter0.40.71.1-0.7-0.9-0.9-0.9-0.7-0.8-0.8-0.8-0.8-0.9-1.0-0.4
Time in familiar zone, hab. session 10.10.10.3-0.6-0.3-0.3-0.3-0.2-0.2-0.2-0.2-0.2-0.2-0.50.0
Time in novel zone, hab. session 10.20.20.40.60.40.40.40.40.50.40.30.40.40.70.3
Total zone transitions, hab. session 10.10.10.4-0.6-0.4-0.4-0.3-0.2-0.3-0.3-0.2-0.2-0.2-0.30.2
Total locomotion distance, hab. session 10.10.10.6-0.4-0.4-0.3-0.3-0.1-0.3-0.3-0.3-0.3-0.3-0.8-0.1
Locomotion velocity, hab. session 10.60.82.0-0.8-0.9-0.9-0.9-0.7-0.8-0.9-0.8-0.9-0.9-1.4-0.7
Time in familiar zone, hab. session 20.30.31.50.3-0.1-0.2-0.3-0.5-0.4-0.4-0.5-0.5-0.7-0.4-1.2
Time in novel zone, hab. session 20.30.31.4-1.0-0.5-0.4-0.30.1-0.1-0.10.10.00.3-0.31.2
Total zone transitions, hab. session 20.10.10.4-0.6-0.3-0.2-0.20.2-0.1-0.10.10.00.1-0.10.6
Total locomotion distance, hab. session 20.50.61.2-0.8-0.9-0.9-0.8-0.5-0.8-0.8-0.7-0.8-0.7-1.1-0.4
Locomotion velocity, hab. session 20.40.60.9-0.7-0.8-0.8-0.8-0.5-0.7-0.8-0.7-0.7-0.7-1.0-0.4
Novel to familiar place preference ratio1.61.72.60.81.21.31.31.31.31.31.51.41.61.21.4
Novelty place preference2.83.04.31.21.61.71.71.71.71.82.01.82.11.61.8
Time in novel zone, NPP test2.93.14.41.21.61.71.71.71.81.82.01.82.11.61.9
Total zone transitions, NPP test0.10.20.8-0.9-0.6-0.5-0.5-0.1-0.3-0.3-0.3-0.3-0.3-0.30.5
Total locomotion distance, NPP test1.01.42.2-1.2-1.3-1.3-1.2-0.9-1.1-1.2-1.2-1.1-1.2-1.5-0.5
Locomotion velocity, NPP test1.01.42.1-1.1-1.3-1.3-1.2-0.9-1.2-1.2-1.2-1.2-1.2-1.5-0.7
Intraocular pressure0.60.91.2-0.7-1.1-1.1-1.0-0.8-1.0-0.9-0.8-1.0-0.8-1.1-0.5
Delta distance traveled before/after self-admin1.31.35.3-0.50.50.60.81.00.90.91.21.11.41.32.3
Delta ambulatory time before/after self-admin1.82.25.4-0.01.11.21.31.61.41.41.61.61.81.42.3
Parametrial fat weight4.811.217.41.82.82.93.13.53.43.53.73.63.73.44.2
Pavlov. Cond. lever latency0.10.10.40.60.30.30.20.20.10.1-0.10.1-0.00.2-0.4
Pavlov. Cond. magazine entry latency0.40.52.11.50.90.80.70.10.50.50.30.40.20.7-1.0
Pavlov. Cond. change in total contacts0.40.40.6-0.6-0.7-0.7-0.7-0.6-0.6-0.6-0.5-0.6-0.7-0.7-0.3
Pavlov. Cond. index score0.00.00.10.30.20.20.1-0.10.10.10.10.10.00.1-0.3
Pavlov. Cond. latency score0.00.00.10.30.20.20.2-0.00.20.20.20.10.10.1-0.2
Pavlov. Cond. lever contacts0.00.10.3-0.5-0.2-0.2-0.1-0.0-0.00.00.20.10.1-0.00.5
Pavlov. Cond. magazine entry number0.20.21.3-1.1-0.6-0.5-0.4-0.0-0.3-0.3-0.2-0.2-0.1-0.30.8
Pavlov. Cond. intertrial magazine entries0.70.92.9-1.7-1.1-1.1-0.9-0.5-0.8-0.8-0.6-0.6-0.6-1.00.6
Pavlov. Cond. lever-magazine prob. diff.0.00.00.20.30.10.10.0-0.2-0.0-0.00.0-0.1-0.1-0.0-0.5
Pavlov. Cond. response bias0.10.10.30.50.40.30.30.10.30.30.30.30.20.3-0.1
Pavlov. Cond. lever latency0.20.30.6-0.20.60.60.60.40.60.50.80.60.60.40.5
Pavlov. Cond. magazine entry latency0.30.40.60.60.50.60.60.80.70.70.50.70.50.80.6
Pavlov. Cond. change in total contacts0.10.20.91.0-0.0-0.0-0.1-0.2-0.2-0.2-0.4-0.3-0.20.1-0.9
Pavlov. Cond. index score0.10.10.30.1-0.5-0.4-0.4-0.1-0.3-0.3-0.5-0.4-0.4-0.1-0.2
Pavlov. Cond. latency score0.10.20.40.2-0.5-0.5-0.4-0.2-0.4-0.4-0.6-0.5-0.5-0.2-0.4
Pavlov. Cond. lever contacts0.10.10.30.5-0.3-0.2-0.2-0.1-0.2-0.2-0.4-0.3-0.2-0.1-0.3
Pavlov. Cond. magazine entry number0.40.51.0-0.5-0.4-0.5-0.5-0.8-0.7-0.7-0.6-0.7-0.7-0.9-1.0
Pavlov. Cond. intertrial magazine entries0.10.10.20.30.40.40.40.40.40.40.40.40.40.30.3
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.3-0.2-0.2-0.10.1-0.1-0.1-0.3-0.1-0.10.10.0
Pavlov. Cond. response bias0.00.00.40.6-0.00.0-0.00.10.00.0-0.2-0.1-0.10.1-0.2
Time in closed arm before self-admin2.63.37.80.41.21.31.52.01.81.82.12.02.11.72.8
Time in closed arm after self-admin0.50.51.10.50.50.50.60.90.70.70.70.70.70.71.1
Time in open arm before self-admin1.51.73.4-0.1-1.0-1.0-1.1-1.4-1.3-1.3-1.4-1.4-1.4-1.4-1.9
Time in open arm after self-admin0.30.32.00.3-0.0-0.1-0.2-0.7-0.4-0.4-0.6-0.5-0.5-0.5-1.4
Bone: periosteal estimation0.61.21.7-0.8-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.3-0.8
Bone: periosteal perimeter0.00.00.10.30.10.10.1-0.00.10.10.00.00.00.1-0.0
Bone: post-yield work0.10.10.5-0.7-0.3-0.3-0.2-0.0-0.1-0.1-0.0-0.0-0.1-0.60.4
Progressive ratio test 1 active lever presses2.32.86.8-2.6-1.9-1.9-1.8-1.6-1.6-1.6-1.3-1.5-1.4-1.5-0.0
Progressive ratio test 1 breakpoint2.63.27.5-2.7-2.0-2.0-1.9-1.7-1.7-1.7-1.4-1.6-1.5-1.7-0.1
Progressive ratio test 1 inactive lever presses4.26.09.4-3.1-2.8-2.7-2.7-2.3-2.5-2.5-2.4-2.4-2.3-2.2-0.8
Progressive ratio test 2 active lever presses3.23.75.4-2.3-2.1-2.1-2.1-2.2-2.0-2.0-2.0-1.9-1.7-1.3-0.8
Progressive ratio test 2 breakpoint3.54.05.5-2.4-2.2-2.2-2.2-2.3-2.1-2.0-2.1-2.0-1.8-1.4-0.9
Progressive ratio test 2 inactive lever presses1.21.92.9-1.6-1.7-1.6-1.6-1.4-1.5-1.4-1.3-1.3-1.2-1.0-0.1
Incentive Sensitization - Responses1.01.42.7-1.0-1.2-1.2-1.3-1.6-1.3-1.2-1.4-1.2-1.0-0.4-0.8
Incentive Sensitization - Breakpoint1.01.32.4-1.1-1.2-1.2-1.2-1.6-1.3-1.2-1.3-1.2-1.0-0.4-0.7
Sum of active levers in priming session hrs 5-60.70.71.10.50.90.90.80.70.90.91.10.90.90.60.6
Progressive ratio2.23.47.4-2.7-2.2-2.1-2.0-1.9-1.9-1.8-1.5-1.7-1.5-1.5-0.1
Food seeking constrained by brief footshock0.20.31.2-1.1-0.6-0.6-0.5-0.2-0.4-0.3-0.2-0.2-0.2-0.40.6
Seeking ratio, punishment vs. effort1.31.83.01.71.51.51.51.61.41.41.11.31.11.20.5
Retroperitoneal fat weight2.08.410.91.92.62.72.83.33.13.13.03.12.92.93.0
Reaction time number correct1.22.23.51.91.51.51.51.21.51.51.51.51.61.60.9
Reaction time mean minus median0.10.10.40.60.40.40.40.40.40.30.40.3-0.00.2-0.1
Reaction time mean minus median AUC0.71.83.81.91.51.51.41.31.41.31.21.20.91.30.3
Reaction time num false alarms1.42.02.9-0.5-1.3-1.3-1.3-1.4-1.4-1.4-1.4-1.5-1.5-1.7-1.7
Reaction time num false alarms AUC2.13.34.0-0.9-1.7-1.7-1.8-1.9-1.9-1.9-1.9-2.0-2.0-2.0-2.0
Reaction time trials correct on left1.22.23.51.91.51.51.51.21.51.51.51.51.61.60.9
Reaction time trials on left1.32.44.12.01.61.61.61.21.51.61.61.51.61.70.8
Reaction time mean0.71.11.91.11.01.01.01.41.11.11.11.10.81.00.8
Reaction time mean AUC0.60.91.51.10.90.90.91.21.01.01.01.00.71.00.6
Median of all reaction times0.81.22.11.11.01.01.01.41.21.11.11.11.01.20.9
Reaction time omissions2.53.65.92.42.22.22.11.91.91.91.71.81.61.80.5
Reaction time false alarm rate3.95.36.3-2.0-2.3-2.3-2.4-2.2-2.4-2.4-2.4-2.4-2.5-2.5-1.9
Reaction time premature initiation rate1.01.42.41.61.51.41.30.81.21.21.11.10.91.2-0.2
Reaction time premature initiations1.62.96.02.42.02.01.81.21.71.71.61.61.51.8-0.0
Std. dev. reaction times0.20.41.01.00.70.70.60.70.60.60.60.50.30.4-0.1
Reaction time trials completed1.32.44.12.01.61.61.61.21.51.61.61.51.61.70.8
Reaction time trials AUC1.32.43.92.01.61.61.61.31.51.61.61.51.71.70.8
Run reversals in cocaine runway, females0.10.10.80.30.0-0.0-0.1-0.1-0.2-0.2-0.4-0.3-0.4-0.5-0.9
Run reversals in cocaine runway, males0.30.32.1-0.7-0.3-0.3-0.10.50.20.20.50.30.30.31.4
Latency to leave start box in cocaine runway0.80.91.1-0.9-1.0-1.0-1.0-1.0-0.9-1.0-0.8-0.9-1.0-1.0-0.8
Latency to leave start box in cocaine runway, F0.20.20.5-0.7-0.6-0.6-0.5-0.4-0.4-0.4-0.3-0.3-0.3-0.50.2
Latency to leave start box in cocaine runway, M1.61.52.7-0.8-1.0-1.1-1.2-1.4-1.2-1.2-1.2-1.3-1.5-1.1-1.6
Std. dev. time between licks in bursts0.70.91.3-1.0-1.1-1.0-1.0-0.8-1.0-1.0-1.1-1.0-0.8-1.0-0.5
Total sessions with >9 infusions0.81.03.7-1.9-1.1-1.1-1.0-1.0-0.8-0.8-0.5-0.7-0.6-1.10.2
Short access day 1 total inactive lever presses0.10.20.7-0.5-0.1-0.1-0.0-0.10.00.10.40.20.60.70.8
Short access day 10 total inactive lever presses0.10.21.30.5-0.0-0.1-0.2-0.7-0.4-0.4-0.5-0.5-0.2-0.1-1.1
Short access day 1 total infusions1.01.33.2-1.8-1.1-1.2-1.2-1.5-1.1-1.1-0.9-1.0-0.9-1.0-0.5
Short access day 10 total infusions0.30.31.5-1.2-0.5-0.6-0.5-0.5-0.4-0.5-0.3-0.4-0.6-0.70.1
Short access total infusions1.72.26.6-2.6-1.7-1.7-1.6-1.4-1.4-1.4-1.1-1.2-1.3-1.40.0
Short access day 1 locomotion1.72.13.2-1.7-1.3-1.4-1.4-1.8-1.5-1.4-1.3-1.4-1.2-1.5-1.2
Short access day 10 total locomotion1.73.16.1-1.8-1.7-1.7-1.8-2.5-1.9-1.8-1.7-1.8-1.5-1.4-1.5
Short access total locomotion4.04.87.4-2.4-2.3-2.3-2.3-2.7-2.3-2.3-2.0-2.2-2.0-1.8-1.5
One hour access (0.3 mA shock)2.02.35.0-2.2-1.7-1.7-1.6-1.6-1.5-1.5-1.3-1.4-1.1-1.3-0.2
Compulsive drug intake0.20.30.60.60.80.70.50.20.50.50.50.40.30.3-0.6
One hour access (shock baseline)1.01.54.3-2.1-1.5-1.5-1.3-1.0-1.2-1.2-1.0-1.0-0.8-0.80.5
Social response proportion2.02.33.20.81.31.31.41.61.51.51.81.61.71.61.8
Social responses0.70.94.8-0.9-0.00.10.31.00.60.71.10.81.00.32.2
Social time0.20.31.8-0.60.10.10.20.50.50.50.60.60.50.31.4
Soleus weight1.85.26.42.02.22.32.32.22.32.42.42.42.42.51.9
Bone: stiffness0.20.42.5-1.0-0.1-0.00.10.50.30.30.50.50.50.31.6
Tibialis anterior weight0.51.62.40.71.31.31.31.31.41.41.51.41.40.91.2
Time to tail flick, vehicle, before self-admin0.00.00.10.10.10.10.0-0.10.00.00.20.00.2-0.3-0.1
Time to tail flick, vehicle, after self-admin1.21.51.91.11.21.31.31.41.31.31.31.31.31.01.0
Time to tail flick, test, before self-admin0.40.41.30.40.30.40.50.80.60.60.60.60.70.71.1
Time to tail flick, test, after self-admin0.40.41.1-0.2-0.4-0.5-0.5-0.8-0.6-0.7-0.7-0.7-0.8-0.6-1.1
Delta time to tail flick, vehicle, before/after SA0.60.60.70.70.80.80.80.90.80.80.70.80.80.80.5
Delta time to tail flick, test, before/after SA2.42.54.2-1.1-1.2-1.3-1.4-1.8-1.6-1.6-1.6-1.6-1.8-1.6-2.1
Tibia length0.00.10.2-0.4-0.3-0.2-0.2-0.1-0.2-0.2-0.2-0.1-0.1-0.50.2
Ambulatory time before self-admin0.30.50.9-0.8-1.0-0.9-0.9-0.5-0.7-0.7-0.6-0.7-0.8-0.6-0.0
Ambulatory time after self-admin1.41.66.2-0.40.50.60.81.31.11.11.41.31.31.42.5
Bone: tissue strength0.10.10.30.2-0.3-0.3-0.3-0.4-0.4-0.3-0.4-0.4-0.4-0.0-0.6
Total heroin consumption0.50.62.5-0.60.30.30.40.80.70.71.00.80.9-0.11.6
Bone: trabecular number2.84.65.92.22.42.42.42.32.32.32.32.22.11.51.1
Bone: trabecular spacing0.81.01.5-0.7-1.0-1.0-1.1-1.2-1.1-1.1-1.1-1.1-1.0-0.5-0.9
Bone: trabecular thickness0.30.41.10.10.30.40.50.70.60.60.70.60.70.41.0
Bone: trabecular tissue density0.30.40.7-0.8-0.8-0.8-0.7-0.5-0.6-0.6-0.7-0.6-0.6-0.20.1
Water consumed over 24 hours0.60.93.71.91.11.10.90.50.70.70.50.60.50.8-0.9
Number of responses in last shaping day0.80.82.7-0.3-0.5-0.5-0.7-1.0-0.9-0.9-1.2-1.0-1.0-0.7-1.6