Hub : Genes

C10h17orf58

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression C10h17orf58 0.42 0.09 0.0e+00 0.4 0.47 0.5 0.51 3.1e-39 3.2e-49 2.0e-52 2.4e-54
2 Adipose mRNA stability C10h17orf58 0.09 0.04 1.6e-09 0.03 0.07 0.05 0.07 8.5e-04 6.0e-08 1.9e-06 7.9e-08
3 IL gene expression C10h17orf58 0.35 0.11 1.6e-07 0.27 0.3 0.17 0.27 4.1e-07 6.8e-08 7.5e-05 2.8e-07
4 Brain mRNA stability C10h17orf58 0.18 0.08 2.0e-10 0.07 0.11 0.12 0.12 5.9e-07 8.6e-11 4.2e-11 1.5e-11
5 PL mRNA stability C10h17orf58 0.12 0.08 2.8e-06 0.03 0.05 0.06 0.05 7.7e-04 1.3e-06 5.7e-07 1.5e-06
6 IC gene expression C10h17orf58 0.51 0.13 0.0e+00 0.32 0.39 0.42 0.43 3.1e-14 2.9e-17 3.2e-19 1.4e-19
7 PL gene expression C10h17orf58 0.43 0.1 0.0e+00 0.46 0.46 0.5 0.5 5.2e-56 2.8e-55 5.9e-62 8.6e-62
8 NAcc gene expression C10h17orf58 0.56 0.09 0.0e+00 0.6 0.56 0.62 0.63 4.8e-114 8.1e-104 3.4e-122 3.0e-123
9 Liver gene expression C10h17orf58 0.13 0.06 2.6e-09 0.03 0.05 0.08 0.06 1.0e-04 7.3e-06 3.4e-09 1.3e-07
10 Adipose gene expression C10h17orf58 0.32 0.07 0.0e+00 0.34 0.37 0.4 0.41 2.8e-38 3.1e-43 2.9e-47 8.5e-49
11 pVTA gene expression C10h17orf58 0.4 0.1 0.0e+00 0.36 0.44 0.44 0.45 6.7e-30 1.5e-38 3.5e-38 2.8e-39
12 BLA gene expression C10h17orf58 0.47 0.14 0.0e+00 0.36 0.35 0.39 0.38 4.1e-20 1.8e-19 1.0e-21 1.6e-21
13 OFC gene expression C10h17orf58 0.36 0.13 2.2e-06 0.23 0.19 0.23 0.23 3.8e-06 2.6e-05 4.2e-06 2.8e-06
14 LHb gene expression C10h17orf58 0.24 0.11 4.0e-03 0.02 -0.01 -0.01 0.01 9.7e-02 6.3e-01 4.9e-01 2.3e-01
15 RMTg mRNA stability C10h17orf58 0.15 0.08 3.1e-03 0.06 0.08 0.01 0.08 1.1e-02 4.2e-03 2.0e-01 4.6e-03
16 RMTg gene expression C10h17orf58 0.15 0.09 8.3e-03 0.12 0.08 0.09 0.1 3.4e-04 3.1e-03 2.6e-03 1.2e-03
17 NAcc mRNA stability C10h17orf58 0.03 0.02 3.8e-03 0.02 0.01 0.01 0.01 3.8e-04 5.0e-03 2.7e-03 6.7e-03
18 BLA mRNA stability C10h17orf58 0.17 0.08 9.9e-06 0.01 0.1 0.09 0.07 8.9e-02 9.7e-06 2.5e-05 1.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.40.62.4-0.9-0.5-0.8-0.7-0.9-1.1-1.0-0.9-0.4-0.7-0.9-0.6-0.7-0.6-0.6-0.4-1.50.1
Area under the delay curve0.20.21.10.10.20.20.2-0.2-0.10.20.2-0.10.30.00.40.4-0.00.6-0.8-1.00.9
BMI with tail2.06.915.7-3.1-3.2-3.2-3.1-2.1-2.0-2.9-2.8-4.0-1.5-2.3-2.6-1.7-3.3-0.3-3.90.5-0.5
BMI without tail4.413.327.3-4.3-4.3-4.4-4.3-3.3-3.0-4.0-4.0-5.1-2.6-3.4-3.7-2.9-4.1-0.8-5.2-0.2-0.8
Body weight3.816.726.0-5.1-4.4-5.0-4.2-4.0-4.1-4.7-4.8-4.7-3.8-4.4-4.5-3.9-3.7-2.0-4.5-2.1-1.1
Weight adjusted by age0.40.61.10.90.60.90.70.60.71.01.00.60.91.01.01.10.20.70.1-0.20.6
Bone surface3.76.714.2-2.9-2.0-2.7-1.8-2.9-3.2-3.0-3.0-0.9-3.0-2.9-2.5-3.1-1.3-3.0-0.5-3.8-1.5
Bone volume2.85.110.6-2.6-1.8-2.4-1.7-2.6-2.8-2.6-2.6-1.2-2.5-2.5-2.1-2.5-1.3-2.2-1.0-3.3-0.9
Breakpoint value in progressive ratio session0.30.31.90.0-0.7-0.3-1.00.6-0.30.30.4-0.50.00.6-0.00.2-0.8-0.80.1-0.0-1.4
Number of licking bursts0.10.10.80.2-0.20.10.20.0-0.10.10.30.4-0.10.20.20.2-0.1-0.50.2-0.9-0.6
Context. condit. distance diff. score0.10.21.4-0.1-0.4-0.2-1.2-0.5-0.3-0.2-0.1-0.6-0.1-0.1-0.10.0-0.5-0.3-0.10.3-0.5
Locomotion velocity, session 10.80.81.3-1.1-1.0-1.1-0.9-0.9-1.1-1.0-1.2-0.9-0.9-0.9-0.9-0.9-0.8-0.7-1.0-0.6-0.4
Locomotion distance, session 10.60.83.7-1.1-1.1-0.8-0.6-1.3-0.7-0.8-1.1-1.0-0.4-0.6-0.4-0.5-1.3-0.2-1.9-0.1-0.1
Locomotion velocity, session 21.41.65.3-1.2-1.6-1.2-1.3-1.0-1.2-0.9-0.9-1.1-1.2-0.6-1.0-1.1-1.6-2.0-0.1-0.4-2.3
Locomotion distance, session 20.50.82.8-0.7-1.4-0.7-1.0-0.8-0.8-0.4-0.5-1.1-0.2-0.0-0.2-0.2-1.7-1.0-1.0-0.3-1.4
Locomotion velocity, session 30.60.73.8-0.2-1.1-0.1-0.90.2-0.00.40.4-1.10.60.90.60.7-2.0-0.1-1.50.1-0.8
Locomotion distance, session 30.30.30.9-0.5-0.7-0.3-0.4-0.4-0.5-0.2-0.2-0.4-0.20.10.1-0.2-0.9-0.9-0.3-0.9-0.9
Stereotopy head waving bouts, day 30.70.81.51.00.80.90.61.10.91.11.00.31.21.01.01.20.31.2-0.20.51.1
Stereotopy head waving duration, day 30.60.71.71.00.60.90.30.90.71.21.10.11.11.11.11.30.11.0-0.40.10.9
Locomotion velocity, session 70.20.21.10.40.30.40.50.50.60.20.40.60.60.50.40.50.50.40.41.00.1
Locomotion distance, session 70.00.00.20.0-0.1-0.10.0-0.4-0.0-0.2-0.20.2-0.0-0.0-0.00.00.4-0.0-0.10.2-0.0
Stereotopy head waving bouts, day 70.70.82.01.0-0.10.8-0.30.90.61.21.30.01.01.41.21.4-0.80.1-0.00.0-0.7
Stereotopy head waving duration, day 71.72.15.01.80.61.60.51.81.22.02.20.91.62.22.02.0-0.30.30.80.2-0.6
Locomotion velocity, session 80.60.71.5-0.8-0.5-0.9-0.9-0.5-1.1-1.0-0.9-0.4-1.0-0.9-0.9-1.1-0.1-1.20.6-0.8-0.9
Locomotion distance, session 80.60.82.1-0.8-1.2-0.9-1.5-1.1-1.0-0.8-0.7-1.1-0.6-0.5-0.6-0.5-1.0-1.1-0.4-0.1-1.3
Degree of sensitization distance0.20.21.0-0.10.4-0.2-0.0-0.4-0.2-0.4-0.60.3-0.4-0.6-0.6-0.51.00.3-0.10.10.7
Degree of sensitization stereotypy0.80.82.30.7-0.70.6-0.70.60.51.01.2-0.20.91.41.11.2-1.5-0.4-0.40.5-1.5
Conditioned locomotion0.20.30.7-0.4-0.3-0.6-0.8-0.1-0.6-0.5-0.5-0.7-0.6-0.6-0.8-0.5-0.1-0.2-0.4-0.3-0.0
Cocaine response after cond. corrected1.01.22.71.41.41.31.60.80.81.21.11.61.01.01.20.91.10.61.0-0.40.9
Cocaine response after cond. not corrected1.31.53.41.61.11.51.50.80.81.41.51.91.01.31.51.11.0-0.11.6-0.6-0.2
Cocaine response before conditioning0.30.43.1-0.0-0.8-0.0-0.6-0.5-0.20.20.4-0.1-0.10.30.40.3-0.9-1.10.1-0.3-1.8
Saline control response1.82.46.7-1.4-2.0-2.0-2.2-1.0-1.2-1.4-1.1-2.6-1.4-1.3-1.9-1.1-1.9-1.0-1.20.2-1.6
Bone: connectivity density1.01.54.3-1.4-0.8-1.3-1.0-1.2-1.6-1.4-1.5-0.5-1.3-1.3-1.2-1.4-0.6-1.2-0.4-2.1-0.3
Bone: cortical apparent density2.43.37.11.41.01.91.41.52.21.61.80.72.52.02.22.40.02.7-1.12.11.9
Bone: cortical area2.84.39.1-2.6-3.0-2.2-2.0-2.4-1.9-2.2-1.9-2.1-1.4-1.6-1.3-1.2-3.0-1.3-3.0-1.0-1.4
Bone: cortical porosity4.24.511.2-1.9-2.5-2.2-2.3-1.9-2.3-1.8-1.5-1.4-2.4-1.9-2.0-1.9-1.2-3.2-0.1-2.0-3.3
Bone: cortical porosity4.24.68.4-2.2-2.8-2.3-2.5-2.2-2.4-1.9-1.6-1.8-2.2-1.8-1.8-1.7-1.8-2.8-0.9-2.1-2.9
Bone: cortical thickness2.84.611.00.8-0.91.50.81.12.21.61.9-0.63.02.42.73.1-2.82.5-3.32.90.7
Bone: cortical thickness1.31.55.00.3-0.90.80.30.31.50.61.1-0.21.61.31.41.7-1.61.1-1.92.2-0.4
Bone: cortical tissue density2.53.47.31.51.11.91.51.62.21.71.80.72.52.02.22.40.12.7-0.92.21.9
Condit. Reinf. active minus inactive responses2.93.27.7-1.6-2.0-1.8-2.4-2.8-1.8-1.4-1.3-2.1-1.9-1.8-1.5-1.2-1.5-2.0-1.1-1.2-2.1
Condit. Reinf. active-inactive response ratio0.91.02.8-0.5-0.9-0.8-1.7-1.6-1.0-0.5-0.5-0.9-1.1-0.9-0.8-0.6-0.4-1.40.1-0.9-1.4
Condit. Reinf. active responses3.74.69.7-2.0-2.4-2.2-2.6-3.1-2.2-2.0-1.7-2.3-2.3-2.4-1.9-1.6-1.6-2.2-1.4-1.7-2.2
Condit. Reinf. inactive responses1.41.83.4-1.5-1.4-1.4-0.9-1.8-1.4-1.6-1.4-1.1-1.5-1.7-1.1-1.2-0.9-1.0-1.3-1.4-0.6
Incentive salience index mean2.53.05.3-1.6-2.1-1.8-2.1-2.3-1.8-1.5-1.2-1.8-1.9-1.7-1.5-1.3-1.5-2.1-0.9-1.3-2.3
Condit. Reinf. lever presses0.50.73.0-0.6-1.3-0.8-0.9-0.4-0.6-0.6-0.1-1.0-0.8-0.5-0.6-0.3-1.1-1.1-0.3-0.5-1.7
Condit. Reinf. active minus inactive responses7.69.815.7-3.0-3.8-3.2-4.0-3.6-3.6-2.7-2.5-2.7-3.0-2.6-2.4-2.4-3.1-3.7-2.1-3.7-3.4
Condit. Reinf. active-inactive response ratio2.32.66.8-1.3-1.7-1.6-1.9-1.7-1.9-1.2-1.0-1.2-1.8-1.4-1.3-1.2-1.1-2.3-0.2-2.6-2.1
Condit. Reinf. active responses9.312.919.6-3.8-4.1-3.9-4.4-4.2-4.0-3.4-3.3-3.3-3.7-3.5-3.2-3.2-3.3-3.8-2.5-3.3-3.3
Condit. Reinf. inactive responses5.57.110.4-3.1-3.2-2.9-3.2-3.2-2.6-2.8-2.7-2.8-2.5-2.7-2.4-2.4-2.9-2.0-2.9-0.9-1.8
Condit. Reinf. lever presses4.56.311.2-2.5-3.3-2.6-2.7-2.9-2.3-2.3-1.9-2.8-2.4-2.1-2.1-1.8-3.3-2.6-2.1-1.3-3.0
Condit. Reinf. lever reinforcers received7.710.716.0-3.4-3.7-3.5-4.0-3.8-3.6-3.2-3.0-3.0-3.4-3.2-3.0-3.0-2.9-3.4-2.3-3.0-3.0
Conditioned reinforcement - actives0.61.03.7-1.0-1.3-1.1-1.4-0.7-0.9-0.7-0.7-1.9-0.7-0.8-0.9-0.6-1.3-0.4-1.3-0.5-0.5
Conditioned reinforcement - inactives1.42.03.7-1.8-1.4-1.7-1.3-1.5-1.5-1.7-1.8-1.9-1.3-1.4-1.5-1.6-1.1-0.9-1.2-0.1-0.5
Conditioned locomotion2.73.55.7-2.2-1.8-2.3-2.1-1.7-2.0-2.2-2.1-2.4-2.0-2.2-2.2-1.9-1.3-1.1-1.6-1.1-0.7
Patch foraging indifference point 0 sec4.99.115.1-3.6-3.3-3.4-2.9-3.9-3.1-3.5-3.4-3.2-3.0-3.4-3.0-2.7-2.5-1.9-3.1-1.5-1.3
Patch foraging indifference point AUC1.42.03.3-1.8-1.3-1.7-1.3-1.2-1.5-1.7-1.8-1.3-1.5-1.5-1.5-1.7-1.4-0.9-1.2-0.7-0.5
Delay disc. indifference point, 0s delay1.11.22.21.21.31.21.51.11.01.11.11.21.01.01.11.00.91.10.6-0.31.3
Delay disc. indifference point, 16s delay0.30.42.2-0.2-0.3-0.3-0.5-0.4-0.4-0.1-0.1-1.00.0-0.3-0.00.3-0.40.4-1.2-1.50.7
Delay disc. indifference point, 2s delay0.40.53.7-0.30.1-0.20.3-1.0-0.8-0.5-0.50.5-0.6-0.8-0.2-0.50.4-0.2-0.3-1.90.8
Delay disc. indifference point, 24s delay1.71.95.1-1.6-1.4-1.6-1.4-1.5-1.3-1.4-1.5-1.8-1.1-1.5-1.2-1.0-1.3-0.2-2.3-1.30.4
Delay disc. indifference point, 4s delay0.80.81.81.10.71.20.90.60.81.11.20.91.01.11.41.20.20.60.4-0.20.4
Delay disc. indifference point, 8s delay0.40.51.90.50.70.60.70.40.50.60.50.30.70.50.80.70.31.1-0.6-0.11.4
Indifference point function ln k0.20.41.60.4-0.50.6-0.0-0.20.50.60.9-0.10.70.60.91.3-0.90.2-0.90.4-0.6
Indifference point function log k0.20.41.60.4-0.50.6-0.0-0.20.50.60.9-0.10.70.60.91.3-0.90.2-0.90.4-0.6
Patch foraging total patch changes 0 sec4.78.914.2-3.6-3.2-3.4-2.9-3.8-3.1-3.5-3.4-3.1-3.0-3.3-3.1-2.8-2.4-1.9-3.0-1.6-1.2
Patch foraging total patch changes 12 sec5.77.411.8-3.2-2.3-3.2-2.4-3.0-3.1-3.3-3.4-2.1-3.3-3.3-3.3-3.3-1.1-2.1-1.4-1.9-0.9
Patch foraging total patch changes 18 sec3.75.68.2-2.9-2.6-2.8-2.4-2.4-2.4-2.6-2.8-2.7-2.4-2.3-2.6-2.5-2.2-1.8-2.1-0.6-1.4
Patch foraging total patch changes 24 sec4.27.210.9-3.3-2.9-3.1-2.7-3.2-2.8-3.1-3.1-2.8-2.6-2.8-2.5-2.5-2.6-1.7-2.9-1.6-1.0
Patch foraging total patch changes 6 sec4.16.310.7-3.1-2.7-2.9-2.1-3.3-2.6-3.0-3.0-2.3-2.6-2.8-2.5-2.5-2.2-1.8-2.0-1.0-1.2
Patch foraging time to switch 0 sec0.81.63.11.61.61.31.31.81.31.31.31.21.21.30.90.91.50.91.70.80.7
Patch foraging water rate 0 sec2.45.08.2-2.8-2.3-2.5-2.3-2.9-2.1-2.7-2.7-2.2-2.2-2.6-2.2-2.2-1.8-1.2-2.4-0.7-0.7
Patch foraging water rate 12 sec0.20.41.90.1-0.50.50.3-0.30.60.40.30.00.90.70.90.9-1.00.5-1.40.2-0.0
Patch foraging water rate 18 sec0.30.51.7-0.5-1.2-0.2-0.7-1.1-0.5-0.3-0.1-0.20.1-0.10.40.4-1.1-0.5-1.3-1.2-0.8
Patch foraging water rate 24 sec0.10.21.4-0.0-0.30.2-0.2-0.4-0.10.30.10.40.10.10.40.2-0.2-0.5-0.4-1.2-0.4
Patch foraging water rate 6 sec0.20.21.9-0.4-0.7-0.1-0.4-0.5-0.0-0.1-0.2-0.20.2-0.10.10.2-0.90.2-1.4-0.50.0
Seeking ratio, delayed vs. immediate footshock0.10.10.6-0.3-0.2-0.2-0.4-0.00.2-0.2-0.2-0.50.1-0.2-0.1-0.0-0.40.6-0.80.50.3
Distance traveled before self-admin0.70.92.11.10.41.10.60.70.61.41.31.01.01.41.41.1-0.1-0.10.5-0.5-0.4
Distance traveled after self-admin0.30.42.30.1-0.70.0-0.5-0.5-0.50.30.40.1-0.20.50.40.1-0.6-1.30.2-0.9-1.5
Extensor digitorum longus weight2.49.422.22.83.92.73.53.23.62.32.21.62.71.81.62.33.34.71.14.24.5
Bone: elastic displacement1.21.33.21.10.21.30.90.91.41.41.50.41.61.41.81.7-0.41.0-0.51.20.1
Bone: elastic work0.30.31.6-0.8-0.9-0.40.1-0.50.0-0.7-0.4-0.60.1-0.3-0.0-0.0-0.90.3-1.30.9-0.1
Bone: endosteal estimation12.026.343.4-5.3-3.7-5.6-4.5-5.6-6.1-5.7-5.8-2.5-6.6-6.0-6.0-6.5-0.8-6.10.1-5.2-3.9
Bone: endosteal perimeter13.127.843.9-5.6-3.9-5.9-4.8-5.7-6.5-5.8-6.1-2.8-6.6-6.1-6.0-6.4-1.3-5.9-0.6-6.0-3.4
Epididymis fat weight0.31.02.0-1.2-0.8-1.3-0.9-0.3-0.9-1.4-1.3-1.0-0.8-1.1-1.4-1.2-0.70.0-1.0-0.60.4
Delta time in closed arm before/after self-admin0.50.51.70.61.10.71.10.50.60.30.31.30.30.30.50.11.20.41.00.30.7
Delta time in open arm before/after self-admin0.20.20.70.30.40.2-0.00.50.40.50.3-0.70.40.40.30.5-0.00.8-0.40.50.8
Diff in mean of infusions in LGA sessions1.31.65.61.20.61.20.81.71.51.31.40.31.61.61.21.60.01.30.12.40.3
Delay discount exponential model param0.20.21.40.0-0.1-0.0-0.10.50.30.00.00.2-0.00.2-0.2-0.2-0.0-0.40.71.2-0.8
Extinction: sum of active levers before priming0.10.10.30.0-0.3-0.2-0.50.1-0.1-0.00.2-0.60.1-0.0-0.10.4-0.30.3-0.5-0.10.1
Active lever presses in extinction session 61.41.42.7-1.2-1.4-1.4-1.5-1.1-1.2-1.2-1.0-1.6-1.3-1.2-1.2-1.0-1.0-1.0-0.8-0.4-1.1
Bone: final force1.32.14.7-1.9-1.9-1.4-1.0-2.2-1.6-1.7-1.6-0.5-1.2-1.3-0.9-1.2-1.3-1.4-1.3-1.6-1.2
Bone: final moment1.32.04.7-1.9-1.9-1.4-0.9-2.2-1.5-1.7-1.6-0.5-1.1-1.3-0.9-1.2-1.4-1.4-1.3-1.5-1.2
Food consumed during 24 hour testing period2.02.85.2-2.1-1.6-2.2-1.7-0.8-1.7-2.0-2.0-2.2-1.6-1.8-2.3-1.8-1.3-0.6-1.6-0.5-0.1
Glucose0.81.22.81.10.51.21.11.41.11.61.40.51.41.71.51.3-0.20.7-0.10.70.1
Heart weight0.30.51.70.4-0.10.60.50.30.40.70.60.10.90.70.91.0-0.50.9-1.3-0.40.8
Delay discount hyperbolic model param0.10.21.3-0.0-0.2-0.1-0.20.40.20.00.0-0.00.00.2-0.2-0.1-0.1-0.40.61.1-0.9
Intermittent access intake day 1-15 change0.20.52.30.51.00.40.70.90.50.20.30.70.00.1-0.1-0.21.40.21.50.90.4
Intermittent access intake escalation0.10.21.20.00.4-0.10.10.3-0.0-0.3-0.10.2-0.4-0.4-0.6-0.60.9-0.11.10.30.1
Intermittent access intake escalation 20.40.52.2-0.00.7-0.20.30.5-0.0-0.5-0.30.5-0.6-0.6-0.9-0.91.4-0.11.50.50.3
Intermitt. access day 1 inactive lever presses0.93.65.7-2.1-1.8-2.2-2.2-1.7-2.0-2.0-1.9-2.3-2.1-2.0-2.4-2.1-1.3-1.7-0.8-0.7-1.6
Intermitt. access day 15 inactive lever presses0.51.02.8-1.1-0.5-1.3-0.8-0.4-0.6-1.4-1.3-1.7-1.0-1.3-1.6-1.2-0.1-0.2-0.10.9-0.1
Intermitt. access escalation Index1.72.44.82.00.81.91.21.61.32.02.11.51.82.12.22.20.50.50.9-0.1-0.3
Intermittent access day 1 total infusions2.33.87.1-2.1-2.7-1.9-2.4-2.2-2.0-1.5-1.7-2.6-1.3-1.2-1.1-1.1-2.7-1.7-2.5-1.5-1.7
Intermittent access day 15 total infusions1.52.25.0-1.7-1.6-1.7-1.7-1.5-1.6-1.5-1.5-2.2-1.4-1.5-1.4-1.3-1.3-1.1-1.3-1.0-0.8
Intermittent access terminal intake (last 3 days)2.83.75.2-2.3-1.7-2.3-1.9-1.9-2.2-2.2-2.3-2.2-2.1-2.2-2.1-2.2-1.0-1.6-0.9-1.5-0.9
Intermittent access total infusions4.65.58.5-2.7-2.7-2.6-2.6-2.6-2.6-2.4-2.5-2.9-2.2-2.2-2.0-2.0-2.2-2.0-2.1-1.8-1.5
Intermittent access day 1 locomotion6.38.012.8-3.1-3.6-3.1-3.5-3.1-2.8-2.8-2.7-3.6-2.4-2.5-2.4-2.1-3.3-2.2-3.0-1.5-2.3
Intermittent access day 15 total locomotion5.09.012.3-3.5-3.2-3.4-3.3-3.2-3.1-3.3-3.3-3.4-3.1-3.2-3.1-3.1-2.4-2.4-2.3-2.0-1.9
Intermittent access total locomotion12.915.521.5-4.5-4.6-4.4-4.5-4.5-4.0-4.3-4.1-4.5-3.7-4.0-3.7-3.5-3.8-3.1-3.7-2.1-2.7
Intermittent access standard deviation0.40.91.8-1.2-0.6-1.1-0.8-0.9-0.8-1.3-1.3-0.9-1.1-1.2-1.2-1.3-0.3-0.6-0.30.3-0.2
Left kidney weight0.21.04.4-0.9-1.7-0.5-0.8-1.1-0.6-0.3-0.4-0.80.10.10.20.1-2.1-0.8-2.1-0.7-1.1
Right kidney weight0.20.83.8-0.8-1.5-0.5-0.5-0.8-0.7-0.3-0.4-0.60.10.10.30.1-1.9-0.6-1.8-1.3-0.7
Cocaine induced anxiety0.20.30.70.5-0.10.70.3-0.40.50.70.7-0.00.60.60.90.7-0.4-0.1-0.00.2-0.7
Post-drug Anxiety0.40.41.00.60.30.90.60.00.80.80.80.30.90.81.00.8-0.10.4-0.00.60.0
Baseline Anxiety0.40.51.80.30.60.30.41.10.70.30.20.10.70.50.20.40.31.3-0.41.11.4
Tail length2.710.515.0-3.9-3.3-3.9-3.3-3.4-3.5-3.7-3.8-2.9-3.5-3.5-3.7-3.8-2.2-2.5-2.4-2.1-1.7
Length with tail1.77.512.5-3.3-2.1-3.1-2.0-2.8-3.3-3.1-3.4-1.6-3.4-3.3-3.1-3.5-0.9-2.4-1.2-3.3-0.9
Length without tail0.20.51.7-0.60.6-0.30.80.2-0.6-0.5-0.70.6-0.7-0.7-0.6-0.91.1-0.10.5-1.31.0
Times rat made contact with spout0.40.51.1-0.8-0.6-0.9-0.5-0.4-0.8-0.7-0.8-0.3-0.8-0.7-0.9-1.1-0.2-0.8-0.1-0.6-0.6
Lifetime Intake5.77.011.8-3.0-3.2-2.9-3.1-3.0-2.8-2.6-2.7-3.4-2.3-2.4-2.2-2.2-2.8-2.1-2.7-1.7-1.8
Liver weight, left4.47.212.5-2.8-2.7-2.9-2.9-2.6-3.1-2.8-2.6-1.5-3.1-2.5-2.5-2.8-1.7-3.5-0.5-3.3-2.9
Liver weight, right0.30.63.4-0.1-0.90.2-0.4-0.20.30.40.1-0.50.80.90.70.6-1.80.2-1.60.7-0.5
Locomotor activity3.45.416.5-2.2-3.7-2.2-2.8-2.5-1.8-1.6-1.4-2.6-1.4-1.1-1.1-1.0-4.1-2.2-2.9-0.5-3.0
Locomotor testing distance3.36.016.5-2.3-3.8-2.4-3.3-2.5-1.8-1.6-1.4-3.1-1.5-1.2-1.5-1.1-4.1-2.2-2.8-0.2-3.2
Locomotor testing rearing1.83.610.6-1.6-2.7-2.0-2.6-1.6-1.3-1.4-1.1-2.1-1.7-1.2-1.8-1.4-2.4-2.2-0.91.0-3.3
Locomotion in novel chamber0.20.31.60.30.10.40.5-0.2-0.10.40.30.80.00.30.50.10.3-0.80.8-1.3-0.7
Locomotion in novel chamber post-restriction1.11.89.2-1.2-0.3-1.00.1-1.6-1.7-1.4-1.50.2-1.6-1.7-1.1-1.70.6-1.30.3-3.0-0.0
Fecal boli incidents, locomotor time 10.40.62.30.91.10.70.90.70.40.60.60.80.20.40.30.41.50.41.1-0.40.7
Change in fecal boli incidents, locomotor task0.40.42.80.20.90.40.90.10.6-0.0-0.10.30.3-0.20.20.10.71.2-0.30.71.7
Time >=10cm from walls, locomotor time 11.21.33.51.20.71.41.21.01.01.51.21.91.21.61.50.90.6-0.11.1-0.3-0.5
Bouts of movement, locomotor time 10.60.72.40.70.90.70.90.71.00.50.50.10.80.30.50.60.81.40.11.51.3
Total resting periods, locomotor time 10.91.02.70.81.30.91.20.91.00.50.50.50.80.30.50.51.31.60.31.61.6
Rest time, locomotor task time 11.31.74.11.22.01.21.91.51.10.90.81.40.70.60.70.52.01.21.60.81.6
Distance moved, locomotor task time 10.60.91.8-1.2-1.1-1.2-1.3-0.6-1.0-1.0-1.1-1.0-0.7-0.7-1.0-0.9-0.8-0.5-1.0-0.4-0.4
Vertical activity count, locomotor time 10.20.61.1-0.9-1.0-0.9-1.1-0.6-0.8-0.8-0.8-0.5-0.5-0.5-0.7-0.6-0.8-0.7-0.7-0.9-0.6
Time >=10cm from walls, locomotor time 20.40.62.40.60.60.60.81.20.50.60.51.30.30.80.30.00.8-0.31.50.4-0.6
Bouts of movement, locomotor time 20.30.41.60.50.50.40.50.90.80.40.5-0.40.70.60.30.60.31.3-0.31.00.9
Total resting periods, locomotor time 20.30.61.70.70.60.60.70.91.00.60.7-0.30.90.80.60.90.21.3-0.31.00.9
Rest time, locomotor task time 25.26.69.13.03.03.03.02.82.52.92.72.12.72.62.72.62.32.41.60.92.3
Distance moved, locomotor task time 20.70.81.8-1.1-1.0-1.2-1.0-0.1-0.8-1.1-1.1-0.5-0.9-0.8-1.3-1.3-0.5-0.9-0.00.3-1.1
Vertical activity count, locomotor time 22.33.25.0-2.1-2.0-2.2-2.1-1.4-1.6-2.1-1.9-1.6-1.8-1.8-2.2-1.9-1.5-1.6-0.80.1-1.7
Light reinforcement 10.61.48.5-0.9-1.5-0.9-1.2-0.4-0.4-0.7-0.4-2.10.1-0.4-0.40.3-2.20.8-2.90.10.4
Light reinforcement 20.40.63.3-0.7-0.5-0.6-0.7-0.2-0.4-0.4-0.5-1.10.1-0.4-0.20.1-1.10.9-1.8-0.41.2
Bone: marrow area11.525.141.6-5.1-3.6-5.4-4.4-5.5-5.9-5.6-5.7-2.3-6.4-5.9-5.9-6.4-0.7-6.00.2-5.1-3.8
Bone: maximum diameter4.58.413.1-3.4-2.8-3.1-2.4-3.6-3.4-3.2-3.2-1.7-3.3-3.2-2.7-3.1-1.9-3.1-1.5-3.4-1.9
Bone: maximum force2.64.79.9-2.7-2.7-2.2-1.5-3.2-2.3-2.4-2.4-1.5-1.8-2.1-1.6-1.9-2.0-1.6-2.8-2.1-1.0
Bone: maximum moment2.54.49.5-2.7-2.6-2.1-1.4-3.1-2.2-2.5-2.4-1.4-1.7-2.1-1.5-1.9-1.9-1.6-2.7-1.9-1.0
Mean time between licks in bursts0.10.21.1-0.30.3-0.30.40.1-0.3-0.4-0.6-0.0-0.2-0.5-0.5-0.50.50.4-0.2-0.71.0
Mean num. licks in bursts0.20.30.6-0.6-0.0-0.6-0.5-0.2-0.3-0.5-0.7-0.8-0.3-0.5-0.7-0.60.10.4-0.50.60.6
Cd content in liver6.06.715.13.23.62.72.32.32.52.32.33.12.01.71.92.03.92.13.41.92.1
Co content in liver1.31.53.11.41.41.30.91.81.21.41.40.91.21.31.21.31.00.91.50.90.7
Cu content in liver0.10.10.3-0.10.3-0.10.50.10.0-0.2-0.20.0-0.4-0.5-0.4-0.40.50.10.2-0.10.4
Fe content in liver0.91.15.0-0.9-1.5-0.6-0.4-1.0-0.7-0.5-0.3-0.5-0.8-0.4-0.2-0.5-1.6-1.8-0.6-0.9-2.2
K content in liver0.50.53.8-0.7-0.6-0.50.0-0.6-0.9-0.4-0.4-0.1-0.7-0.5-0.2-0.5-0.5-1.1-0.1-2.0-0.7
Mg content in liver0.70.71.50.81.00.91.20.90.70.80.90.90.60.70.80.70.80.51.1-0.20.7
Mn content in liver0.30.31.6-0.3-0.70.00.1-0.8-0.40.0-0.00.1-0.10.10.50.1-1.0-0.8-0.3-1.3-0.7
Na content in liver0.70.73.1-0.4-1.1-0.6-1.0-0.3-1.0-0.10.2-0.7-0.6-0.1-0.00.0-1.2-1.30.1-1.8-1.5
Rb content in liver1.82.14.61.51.02.02.11.01.61.71.91.61.51.82.21.70.30.50.70.8-0.0
Se content in liver0.60.72.10.4-0.40.60.30.10.31.00.8-0.10.91.01.41.2-1.40.3-1.4-0.5-0.0
Sr content in liver0.50.40.8-0.8-0.5-0.9-0.8-0.1-0.8-0.9-0.9-0.4-0.6-0.6-0.9-0.7-0.4-0.3-0.0-0.40.0
Zn content in liver0.50.61.41.00.81.00.70.60.71.20.90.80.91.01.10.80.50.40.20.00.4
Bone: minimum diameter11.420.729.1-5.2-4.0-5.2-4.3-5.0-5.4-5.3-5.3-3.3-5.3-5.3-5.0-5.2-1.9-4.5-1.9-4.5-2.6
Time in familiar zone, hab. session 10.50.51.3-0.50.2-0.50.0-0.4-0.6-0.8-0.80.1-1.0-1.1-1.1-1.11.0-0.40.4-0.70.2
Time in novel zone, hab. session 10.70.71.80.7-0.00.70.20.60.80.90.90.01.21.21.11.2-0.80.7-0.51.30.0
Total zone transitions, hab. session 11.11.63.7-1.4-1.8-1.2-1.4-1.4-1.0-1.2-1.1-1.7-0.7-0.9-0.9-0.7-1.9-0.6-1.90.1-0.9
Total locomotion distance, hab. session 12.33.36.4-2.1-2.5-1.9-1.8-2.1-1.5-1.8-1.9-2.3-1.2-1.4-1.5-1.3-2.5-1.0-2.5-0.1-1.1
Locomotion velocity, hab. session 12.33.25.2-2.2-2.3-2.0-1.8-2.0-1.7-1.8-2.0-2.1-1.4-1.6-1.6-1.6-2.2-1.2-2.1-0.6-1.1
Time in familiar zone, hab. session 21.51.62.7-1.1-0.9-1.4-1.7-1.1-1.5-1.4-1.3-0.6-1.6-1.3-1.4-1.40.2-1.70.5-0.9-1.3
Time in novel zone, hab. session 21.41.43.41.01.11.31.80.71.41.10.80.91.51.11.31.10.21.6-0.50.91.6
Total zone transitions, hab. session 20.70.92.0-1.0-1.4-1.0-1.4-0.4-0.9-0.9-0.8-1.3-0.4-0.4-0.8-0.5-1.3-0.6-1.30.1-0.9
Total locomotion distance, hab. session 21.21.63.7-1.5-1.4-1.4-1.3-1.1-1.1-1.4-1.5-1.8-0.9-1.2-1.3-1.1-1.2-0.2-1.90.1-0.0
Locomotion velocity, hab. session 21.01.33.3-1.4-1.2-1.3-1.2-0.9-1.1-1.3-1.4-1.6-0.8-1.1-1.2-1.0-1.1-0.1-1.8-0.00.2
Novel to familiar place preference ratio0.60.61.4-1.0-0.8-0.8-0.4-1.2-0.7-1.0-1.0-0.5-0.8-1.1-0.7-0.8-0.8-0.6-0.7-0.4-0.3
Novelty place preference0.40.40.9-0.8-0.7-0.6-0.4-0.9-0.6-0.8-0.7-0.4-0.6-0.8-0.5-0.6-0.8-0.5-0.5-0.2-0.4
Time in novel zone, NPP test0.40.41.1-0.8-0.8-0.5-0.5-1.0-0.5-0.7-0.6-0.4-0.5-0.7-0.4-0.5-1.0-0.6-0.5-0.1-0.6
Total zone transitions, NPP test1.21.76.4-1.3-2.0-1.1-1.6-1.3-1.0-0.9-0.9-1.6-0.3-0.4-0.4-0.3-2.4-0.5-2.5-0.5-0.8
Total locomotion distance, NPP test1.62.13.7-1.8-1.7-1.6-1.4-1.7-1.3-1.6-1.8-1.5-1.1-1.3-1.2-1.3-1.9-0.8-1.9-0.4-0.6
Locomotion velocity, NPP test1.21.75.6-1.6-1.5-1.4-1.3-1.4-1.1-1.4-1.6-1.7-0.7-1.1-1.0-0.9-1.6-0.1-2.4-0.20.1
Intraocular pressure0.71.15.3-1.0-0.9-0.9-0.9-0.6-0.4-0.4-0.9-2.2-0.1-0.5-0.7-0.5-1.20.6-2.30.90.5
Delta distance traveled before/after self-admin0.60.71.8-0.7-1.3-0.7-1.2-0.8-0.6-0.5-0.4-1.1-0.4-0.3-0.4-0.2-1.3-0.6-1.00.2-1.1
Delta ambulatory time before/after self-admin0.40.61.0-0.8-1.0-0.8-1.0-0.9-0.7-0.8-0.6-0.9-0.7-0.7-0.7-0.5-0.7-0.5-0.8-0.3-0.6
Parametrial fat weight0.61.57.60.81.90.71.40.70.10.20.02.00.1-0.20.1-0.12.80.42.2-0.91.6
Pavlov. Cond. lever latency3.03.88.81.82.92.02.91.31.81.41.02.51.41.11.30.93.02.01.71.22.6
Pavlov. Cond. magazine entry latency3.74.77.4-2.2-2.7-2.4-2.7-2.0-2.3-1.8-1.7-2.5-2.2-1.9-1.9-1.7-2.6-2.3-1.4-1.7-2.3
Pavlov. Cond. change in total contacts3.73.98.9-2.0-2.6-2.1-3.0-1.6-1.9-1.6-1.2-2.6-1.8-1.6-1.6-1.2-2.7-2.0-1.2-0.9-2.4
Pavlov. Cond. index score4.15.19.9-2.2-3.0-2.4-3.1-1.9-2.3-1.8-1.5-2.8-2.1-1.7-1.8-1.5-2.9-2.4-1.6-1.8-2.6
Pavlov. Cond. latency score3.94.910.0-2.1-3.0-2.4-3.2-1.8-2.3-1.7-1.4-2.8-1.9-1.6-1.7-1.4-3.0-2.4-1.8-1.7-2.7
Pavlov. Cond. lever contacts2.32.86.0-1.5-2.3-1.8-2.4-1.0-1.6-1.3-0.9-2.0-1.5-1.2-1.4-1.0-2.2-1.9-0.9-1.0-2.4
Pavlov. Cond. magazine entry number2.53.26.31.72.21.92.51.71.91.31.12.31.71.51.41.22.22.01.01.52.1
Pavlov. Cond. intertrial magazine entries2.02.46.0-1.8-1.7-1.5-1.5-2.4-1.4-1.6-1.5-1.8-1.3-1.8-1.2-1.1-1.5-0.6-2.1-1.0-0.3
Pavlov. Cond. lever-magazine prob. diff.3.94.99.1-2.2-2.9-2.4-3.0-1.9-2.3-1.7-1.5-2.7-2.0-1.7-1.7-1.5-2.9-2.4-1.7-1.8-2.5
Pavlov. Cond. response bias3.74.67.8-2.1-2.8-2.3-2.8-2.0-2.3-1.7-1.5-2.5-2.1-1.8-1.7-1.5-2.6-2.4-1.3-1.9-2.5
Pavlov. Cond. lever latency1.01.32.80.91.61.01.11.41.10.80.61.21.00.70.70.61.71.50.81.21.6
Pavlov. Cond. magazine entry latency1.82.24.21.71.21.81.71.71.41.91.81.41.62.01.91.60.50.51.10.10.1
Pavlov. Cond. change in total contacts0.91.43.8-0.8-1.3-1.1-1.2-1.1-1.3-0.7-0.6-1.1-1.3-0.8-0.9-0.8-1.1-1.9-0.2-1.5-2.0
Pavlov. Cond. index score0.30.42.4-0.1-0.9-0.2-0.4-0.5-0.50.10.1-0.5-0.30.20.1-0.0-1.1-1.2-0.0-0.9-1.6
Pavlov. Cond. latency score0.30.42.60.1-0.8-0.0-0.3-0.3-0.30.30.3-0.3-0.10.40.30.2-1.1-1.20.0-0.8-1.6
Pavlov. Cond. lever contacts0.81.13.2-0.8-1.6-1.0-1.0-1.3-0.9-0.7-0.5-1.3-0.9-0.6-0.6-0.4-1.8-1.2-1.1-0.9-1.5
Pavlov. Cond. magazine entry number2.22.85.8-2.1-1.1-2.0-1.5-1.6-1.6-2.3-2.2-1.4-1.9-2.4-2.3-2.0-0.3-0.5-1.0-0.50.2
Pavlov. Cond. intertrial magazine entries7.411.120.7-4.0-2.1-4.2-3.1-2.8-3.7-4.3-4.4-2.7-4.0-4.5-4.5-4.4-0.8-1.8-1.5-2.1-0.1
Pavlov. Cond. lever-magazine prob. diff.0.30.32.00.1-0.7-0.0-0.2-0.4-0.30.20.3-0.3-0.20.30.30.1-1.0-1.10.1-0.8-1.4
Pavlov. Cond. response bias0.40.61.8-0.4-1.1-0.5-0.5-0.9-0.6-0.3-0.2-0.7-0.5-0.2-0.2-0.2-1.4-1.1-0.6-0.9-1.3
Time in closed arm before self-admin0.70.93.7-0.9-1.6-0.7-1.3-0.8-0.4-0.5-0.4-1.0-0.2-0.1-0.3-0.2-1.9-0.7-1.30.5-1.5
Time in closed arm after self-admin0.20.32.00.30.40.50.70.40.40.20.11.40.30.50.3-0.10.4-0.20.70.4-0.2
Time in open arm before self-admin1.41.62.41.51.11.41.51.41.11.41.51.51.41.51.51.30.80.71.00.10.5
Time in open arm after self-admin0.10.10.50.30.50.20.10.40.10.40.3-0.50.20.20.20.30.30.50.0-0.20.7
Bone: periosteal estimation8.918.825.9-4.9-4.1-4.8-4.0-5.1-5.0-5.0-4.9-2.7-5.0-4.9-4.6-4.9-2.2-4.7-1.7-4.1-3.2
Bone: periosteal perimeter4.78.112.9-3.1-2.9-3.1-2.8-3.4-3.6-3.0-2.9-1.8-3.1-2.9-2.5-2.8-1.7-3.3-1.2-3.6-2.3
Bone: post-yield work1.82.74.4-1.8-1.5-1.7-1.1-2.1-1.9-2.0-1.9-0.9-1.9-1.7-1.7-2.0-0.8-2.0-0.7-1.5-1.4
Progressive ratio test 1 active lever presses4.86.09.9-2.8-3.1-2.7-2.9-2.6-2.5-2.4-2.3-3.1-2.0-2.1-2.1-1.8-2.9-1.7-2.9-1.3-1.7
Progressive ratio test 1 breakpoint5.36.410.5-3.0-3.2-2.8-3.0-2.7-2.6-2.6-2.5-3.2-2.1-2.3-2.3-2.0-2.8-1.7-2.9-1.3-1.6
Progressive ratio test 1 inactive lever presses5.88.413.0-3.3-3.5-3.2-3.2-3.2-3.0-3.1-3.0-3.6-2.6-2.7-2.6-2.4-2.9-2.4-2.7-1.7-2.2
Progressive ratio test 2 active lever presses4.65.39.0-2.6-2.3-2.6-2.6-2.4-2.7-2.2-2.4-3.0-2.3-2.3-2.2-2.3-1.8-1.8-1.9-2.3-1.0
Progressive ratio test 2 breakpoint4.95.69.0-2.7-2.4-2.7-2.6-2.4-2.8-2.3-2.5-3.0-2.4-2.4-2.3-2.4-1.7-1.9-1.8-2.4-1.1
Progressive ratio test 2 inactive lever presses2.94.711.4-2.6-2.3-2.4-2.3-2.4-2.2-2.3-2.3-3.4-1.8-2.1-2.0-1.8-2.1-1.0-2.6-1.1-0.5
Incentive Sensitization - Responses1.72.46.1-1.6-1.1-1.8-1.6-1.2-2.1-1.4-1.7-1.7-1.6-1.5-1.6-1.8-0.5-1.5-0.6-2.5-0.5
Incentive Sensitization - Breakpoint1.82.36.1-1.6-1.1-1.8-1.5-1.2-2.1-1.4-1.7-1.6-1.7-1.5-1.6-1.8-0.5-1.5-0.5-2.5-0.5
Sum of active levers in priming session hrs 5-60.80.72.31.0-0.30.7-0.30.50.81.11.5-0.40.91.10.81.5-0.60.3-0.10.7-0.8
Progressive ratio0.30.43.10.30.90.40.5-0.1-0.20.20.00.9-0.10.00.4-0.11.2-0.20.9-1.80.6
Food seeking constrained by brief footshock2.53.16.2-1.8-1.0-2.1-1.5-1.0-2.0-2.1-2.0-0.8-2.3-1.9-2.4-2.50.1-2.21.0-1.1-1.6
Seeking ratio, punishment vs. effort1.72.44.0-1.7-1.8-1.9-1.8-1.1-1.4-1.7-1.5-1.7-1.7-1.5-2.0-1.6-1.5-1.4-0.70.4-1.7
Retroperitoneal fat weight0.31.43.8-1.5-0.8-1.5-0.7-0.7-1.0-1.8-1.7-1.0-1.3-1.6-1.9-1.6-0.3-0.1-0.9-0.20.3
Reaction time number correct0.50.92.11.00.61.20.70.40.71.31.00.81.21.11.41.30.30.9-0.5-0.50.8
Reaction time mean minus median0.51.12.41.11.51.11.21.31.20.80.91.30.70.70.60.61.51.11.00.61.0
Reaction time mean minus median AUC0.51.32.31.31.11.51.30.81.41.21.31.51.21.11.41.40.81.10.30.10.8
Reaction time num false alarms4.15.88.6-2.7-2.9-2.6-2.8-2.7-2.7-2.1-2.2-2.3-2.4-2.1-2.0-2.2-2.5-2.7-1.9-2.2-2.3
Reaction time num false alarms AUC3.55.47.3-2.6-2.7-2.5-2.7-2.6-2.7-2.2-2.2-2.1-2.4-2.2-2.0-2.2-2.2-2.5-1.6-2.4-2.0
Reaction time trials correct on left0.50.92.11.00.61.20.70.40.71.31.00.81.21.11.41.30.30.9-0.5-0.50.8
Reaction time trials on left0.50.92.01.00.61.20.80.40.71.31.00.91.21.11.41.30.40.9-0.5-0.50.9
Reaction time mean0.81.22.51.41.21.41.40.71.31.21.21.60.91.01.31.11.10.41.10.30.2
Reaction time mean AUC1.01.72.71.61.31.61.51.01.61.41.51.61.11.21.41.31.10.61.30.60.1
Median of all reaction times0.71.01.91.20.91.31.20.41.11.11.11.40.91.01.31.10.70.20.90.3-0.2
Reaction time omissions0.30.41.8-0.10.90.00.90.00.2-0.4-0.60.4-0.2-0.6-0.4-0.61.30.70.10.11.3
Reaction time false alarm rate3.85.37.0-2.5-2.5-2.6-2.6-2.2-2.5-2.3-2.2-2.1-2.6-2.2-2.3-2.5-1.9-2.6-0.9-1.7-2.3
Reaction time premature initiation rate1.11.52.8-1.4-1.5-1.4-1.4-1.5-1.0-1.4-1.1-1.7-1.1-1.3-1.1-0.8-1.4-0.4-1.70.2-0.5
Reaction time premature initiations0.30.62.8-0.8-1.0-0.7-0.8-1.0-0.6-0.6-0.6-1.0-0.4-0.7-0.4-0.1-1.00.1-1.7-0.30.1
Std. dev. reaction times0.81.64.31.31.81.31.61.11.30.90.91.90.60.60.80.62.10.81.70.40.9
Reaction time trials completed0.50.92.01.00.61.20.80.40.71.31.00.91.21.11.41.30.40.9-0.5-0.50.9
Reaction time trials AUC0.50.91.91.00.71.20.80.30.71.20.90.91.21.01.41.30.50.9-0.4-0.40.9
Run reversals in cocaine runway, females1.81.84.41.11.71.11.51.71.50.80.80.81.20.90.60.91.52.10.91.81.9
Run reversals in cocaine runway, males0.40.40.90.60.90.70.90.30.50.60.50.70.40.30.60.40.90.60.60.20.8
Latency to leave start box in cocaine runway0.10.10.70.1-0.30.10.10.50.30.40.3-0.30.40.60.20.2-0.70.1-0.20.8-0.4
Latency to leave start box in cocaine runway, F0.50.52.50.1-0.80.2-0.30.20.30.60.6-0.90.71.00.60.6-1.6-0.2-0.80.8-1.0
Latency to leave start box in cocaine runway, M0.20.20.90.20.50.00.40.80.1-0.1-0.00.5-0.2-0.1-0.3-0.30.90.10.90.30.2
Std. dev. time between licks in bursts0.10.10.5-0.00.2-0.1-0.30.70.0-0.1-0.1-0.50.1-0.0-0.30.00.10.6-0.20.40.7
Total sessions with >9 infusions1.82.28.1-1.3-2.2-1.3-2.1-1.1-0.9-0.7-0.7-2.5-0.2-0.3-0.4-0.1-2.8-0.2-2.70.0-0.9
Short access day 1 total inactive lever presses3.44.59.1-2.6-2.5-2.3-2.3-2.5-2.0-2.2-2.4-3.0-1.7-1.8-1.7-1.8-2.3-1.4-2.4-0.5-1.2
Short access day 10 total inactive lever presses0.10.30.8-0.5-0.0-0.3-0.1-0.7-0.0-0.7-0.7-0.9-0.3-0.8-0.6-0.3-0.00.5-0.30.80.5
Short access day 1 total infusions3.04.012.8-1.8-3.1-1.7-2.9-2.1-1.4-1.0-1.0-3.3-0.6-0.7-0.6-0.3-3.6-0.8-3.5-0.3-1.6
Short access day 10 total infusions5.47.011.4-3.2-3.2-3.0-3.1-2.7-2.6-2.9-2.9-3.4-2.3-2.4-2.4-2.2-2.9-1.7-2.8-0.8-1.5
Short access total infusions4.15.210.2-2.5-3.2-2.3-3.0-2.5-2.1-2.0-1.9-3.2-1.6-1.6-1.5-1.4-3.1-1.6-2.8-0.8-1.9
Short access day 1 locomotion5.06.216.8-2.7-3.3-2.5-3.2-2.6-1.9-2.2-2.0-4.0-1.3-1.8-1.7-1.1-3.7-0.5-4.1-0.3-0.8
Short access day 10 total locomotion4.78.713.1-3.4-3.3-3.5-3.6-3.0-2.9-3.4-3.1-3.1-3.0-3.2-3.4-2.8-2.5-2.1-2.4-0.8-2.0
Short access total locomotion5.76.912.3-3.1-3.3-3.0-3.4-2.6-2.3-2.7-2.6-3.5-2.0-2.3-2.3-1.8-3.3-1.2-3.5-0.5-1.3
One hour access (0.3 mA shock)1.11.32.1-1.2-1.3-1.3-1.4-1.0-1.4-1.0-1.0-1.4-1.1-0.9-1.1-1.2-1.0-1.3-0.6-1.0-1.0
Compulsive drug intake0.91.02.51.20.81.21.20.90.81.21.21.61.01.31.31.00.60.01.1-0.1-0.1
One hour access (shock baseline)1.52.34.5-1.8-1.4-1.8-1.7-1.3-1.6-1.6-1.7-2.1-1.5-1.6-1.6-1.7-1.0-1.0-1.2-0.9-0.5
Social response proportion0.20.20.80.50.20.60.90.00.70.50.60.30.40.30.60.5-0.20.4-0.20.30.1
Social responses0.70.93.1-0.8-1.6-0.8-1.0-1.0-0.5-0.6-0.4-1.1-0.6-0.5-0.5-0.3-1.8-0.9-1.2-0.2-1.5
Social time0.60.92.31.11.20.91.11.10.71.01.01.00.50.70.70.51.40.31.5-0.30.3
Soleus weight0.30.83.1-0.6-1.4-0.7-1.4-0.7-0.7-0.1-0.1-1.3-0.3-0.2-0.10.2-1.8-0.6-1.2-0.7-1.0
Bone: stiffness1.82.95.8-2.0-2.1-1.6-1.1-2.3-2.0-1.8-1.7-0.6-1.5-1.4-1.2-1.5-1.5-1.9-1.7-2.4-1.4
Tibialis anterior weight0.20.62.3-0.40.2-0.6-0.30.50.2-0.6-0.4-1.2-0.2-0.8-1.1-0.1-0.01.4-0.61.51.4
Time to tail flick, vehicle, before self-admin1.21.35.11.11.31.21.50.40.40.90.82.30.30.80.90.41.7-0.31.9-1.20.2
Time to tail flick, vehicle, after self-admin0.20.21.50.20.50.40.4-0.3-0.10.30.10.50.2-0.00.50.20.60.2-0.1-1.20.8
Time to tail flick, test, before self-admin0.30.31.60.60.60.50.50.10.50.10.50.7-0.10.10.10.20.9-0.11.30.9-0.3
Time to tail flick, test, after self-admin0.00.00.10.1-0.10.0-0.0-0.3-0.1-0.10.1-0.0-0.2-0.2-0.10.1-0.1-0.0-0.0-0.2-0.1
Delta time to tail flick, vehicle, before/after SA0.70.61.7-1.0-0.2-1.0-0.5-0.5-0.7-1.1-1.2-0.8-0.9-1.3-1.1-1.10.2-0.1-0.3-0.10.5
Delta time to tail flick, test, before/after SA0.10.11.30.00.00.10.1-0.5-0.30.1-0.00.3-0.1-0.10.2-0.00.1-0.3-0.0-1.20.0
Tibia length0.30.83.6-0.7-1.4-0.3-0.4-1.1-0.6-0.0-0.3-0.30.20.20.50.1-1.4-0.6-1.9-1.6-0.7
Ambulatory time before self-admin0.30.41.20.70.20.70.40.50.31.00.90.80.61.11.00.7-0.2-0.40.5-0.6-0.6
Ambulatory time after self-admin0.30.31.3-0.3-0.9-0.3-0.8-0.7-0.5-0.1-0.0-0.4-0.30.10.0-0.0-0.9-0.9-0.4-0.6-1.2
Bone: tissue strength0.50.51.50.5-0.40.70.5-0.00.40.90.70.21.01.01.20.8-0.80.0-1.0-0.3-0.4
Total heroin consumption1.11.35.2-0.5-1.5-0.8-1.6-0.9-1.2-0.2-0.1-0.6-0.7-0.1-0.2-0.3-1.3-1.9-0.3-2.0-2.3
Bone: trabecular number1.01.75.8-1.4-1.1-1.4-1.2-1.4-1.7-1.4-1.5-0.7-1.3-1.3-1.0-1.2-1.0-1.2-0.7-2.4-0.4
Bone: trabecular spacing0.30.41.20.70.50.50.40.90.70.70.70.40.40.60.30.40.70.30.71.1-0.1
Bone: trabecular thickness0.70.91.6-1.1-0.5-1.0-0.4-0.9-1.0-1.2-1.2-0.9-0.9-1.2-0.9-1.0-0.4-0.1-1.1-1.30.7
Bone: trabecular tissue density0.50.83.70.30.10.80.50.10.60.70.50.41.30.91.31.0-0.11.2-1.90.11.2
Water consumed over 24 hours0.30.41.4-0.8-0.9-0.70.0-0.2-0.3-0.7-0.6-0.6-0.3-0.3-0.5-0.5-1.0-0.1-1.20.1-0.2
Number of responses in last shaping day0.20.21.1-0.4-0.7-0.3-0.6-0.6-0.1-0.2-0.3-0.9-0.1-0.1-0.1-0.0-1.00.0-1.00.1-0.2