Hub : Genes

Bccip

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Bccip 0.1 0.05 1.4e-12 0.07 0.11 0.11 0.1 8.2e-09 9.9e-13 2.3e-12 3.4e-12
2 PL mRNA stability Bccip 0.17 0.09 5.2e-14 0.1 0.14 0.12 0.13 1.0e-10 1.1e-14 4.7e-13 2.0e-14
3 BLA mRNA stability Bccip 0.08 0.06 1.3e-03 0.04 0.04 0.03 0.04 2.9e-03 2.4e-03 9.5e-03 2.9e-03
4 pVTA mRNA stability Bccip 0.2 0.15 6.4e-03 0.03 0.05 0.02 0.05 1.9e-02 3.5e-03 3.8e-02 3.7e-03
5 LHb mRNA stability Bccip 0.32 0.16 5.2e-06 0.21 0.24 0.22 0.24 1.1e-05 1.9e-06 5.8e-06 2.0e-06
6 Adipose mRNA stability Bccip 0.07 0.04 6.8e-07 0.04 0.04 0.04 0.04 1.8e-05 2.1e-05 1.1e-05 1.1e-05
7 pVTA gene expression Bccip 0.56 0.14 1.4e-13 0.32 0.31 0.3 0.32 1.6e-14 6.5e-14 9.9e-14 2.1e-14
8 Liver gene expression Bccip 0.59 0.15 0.0e+00 0.36 0.37 0.38 0.38 2.7e-41 1.2e-43 2.1e-44 2.9e-44
9 Brain gene expression Bccip 0.43 0.15 0.0e+00 0.32 0.31 0.31 0.32 6.2e-31 4.9e-29 2.8e-29 6.9e-31
10 PL gene expression Bccip 0.39 0.13 0.0e+00 0.29 0.3 0.3 0.31 1.9e-32 9.6e-34 1.8e-33 4.3e-34
11 RMTg gene expression Bccip 0.31 0.14 7.4e-08 0.26 0.25 0.23 0.26 1.6e-07 1.9e-07 5.7e-07 1.5e-07
12 LHb gene expression Bccip 0.37 0.17 5.8e-07 0.28 0.27 0.26 0.27 1.9e-07 4.0e-07 8.6e-07 3.2e-07
13 OFC gene expression Bccip 0.3 0.16 1.4e-04 0.12 0.1 0.1 0.08 9.5e-04 2.0e-03 2.8e-03 6.1e-03
14 IL gene expression Bccip 0.22 0.15 3.1e-03 0.07 0.03 0.03 0.05 1.2e-02 7.7e-02 8.1e-02 3.0e-02
15 Brain mRNA stability Bccip 0.12 0.07 2.6e-12 0.15 0.15 0.14 0.15 5.2e-14 1.9e-13 4.1e-13 1.4e-13
16 NAcc gene expression Bccip 0.25 0.1 0.0e+00 0.24 0.25 0.24 0.25 1.2e-27 2.6e-28 7.2e-28 9.2e-29
17 BLA gene expression Bccip 0.61 0.2 5.6e-17 0.3 0.3 0.31 0.31 1.0e-16 2.0e-16 5.2e-17 5.6e-17
18 IL mRNA stability Bccip 0.39 0.18 3.9e-05 0.07 0.14 0.15 0.14 8.5e-03 3.1e-04 2.0e-04 3.3e-04
19 Liver mRNA stability Bccip 0.26 0.14 2.0e-13 0.08 0.09 0.11 0.1 1.2e-09 1.1e-09 6.2e-12 4.5e-11
20 RMTg mRNA stability Bccip 0.11 0.08 9.6e-03 0.04 0.03 0.05 0.04 2.8e-02 4.7e-02 2.0e-02 3.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density2.33.94.52.02.12.12.02.12.0-2.0-2.1-1.91.92.1-1.9-1.9-2.1-2.11.9-1.9-1.7-1.6-1.3
Area under the delay curve0.10.10.3-0.4-0.5-0.4-0.4-0.3-0.40.40.40.3-0.3-0.60.10.10.30.0-0.40.30.2-0.30.5
BMI with tail0.30.92.2-1.1-1.2-1.1-1.2-0.7-1.00.90.50.8-0.9-0.71.01.00.40.1-0.70.81.5-0.4-1.3
BMI without tail1.63.36.61.51.61.71.71.81.6-1.8-2.0-1.91.81.7-1.5-1.5-1.8-2.21.8-1.8-1.2-2.6-2.2
Body weight0.10.33.6-0.1-0.2-0.2-0.3-0.1-0.20.3-0.10.2-0.2-0.00.30.30.1-0.4-0.30.11.4-0.1-1.9
Weight adjusted by age0.50.61.20.30.60.60.70.50.9-1.0-0.7-0.90.90.5-1.1-1.1-0.4-0.41.0-0.6-0.7-0.8-0.3
Bone surface2.03.55.72.42.32.22.22.12.0-1.9-2.0-1.81.82.1-1.7-1.7-1.8-1.91.6-1.7-0.5-0.8-1.8
Bone volume2.74.56.92.62.62.52.42.42.2-2.1-2.3-2.12.12.4-1.9-1.9-2.1-2.31.9-2.0-1.1-1.1-1.9
Breakpoint value in progressive ratio session1.61.73.5-1.2-1.1-1.1-1.0-1.4-1.41.11.31.1-1.1-1.71.21.21.91.6-1.21.31.61.31.3
Number of licking bursts0.40.41.0-0.7-0.8-0.8-0.9-0.6-0.40.80.70.8-0.7-0.40.30.30.30.4-0.70.8-0.10.61.0
Context. condit. distance diff. score1.61.93.81.31.31.41.31.51.4-1.3-1.6-1.31.31.3-1.4-1.4-1.5-1.61.3-1.3-0.6-1.4-1.9
Locomotion velocity, session 10.10.10.30.1-0.1-0.1-0.2-0.0-0.40.40.10.4-0.3-0.20.50.5-0.1-0.1-0.30.40.3-0.00.4
Locomotion distance, session 10.10.10.6-0.2-0.2-0.2-0.2-0.0-0.0-0.00.10.00.00.20.10.1-0.3-0.20.20.0-0.8-0.40.5
Locomotion velocity, session 20.10.20.6-0.0-0.2-0.2-0.3-0.2-0.30.40.30.5-0.4-0.20.40.40.30.3-0.60.40.40.80.7
Locomotion distance, session 21.01.42.3-1.2-1.5-1.4-1.5-1.1-1.21.31.21.3-1.3-0.51.51.50.60.6-1.11.30.00.81.4
Locomotion velocity, session 30.10.20.4-0.2-0.4-0.4-0.5-0.3-0.40.60.20.6-0.5-0.30.50.5-0.00.1-0.50.50.50.30.1
Locomotion distance, session 32.22.43.2-1.8-1.7-1.8-1.8-1.7-1.61.71.51.6-1.6-1.61.51.51.41.6-1.51.61.40.80.8
Stereotopy head waving bouts, day 30.10.10.50.50.40.40.40.30.4-0.2-0.1-0.20.20.5-0.4-0.4-0.1-0.20.1-0.3-0.60.70.6
Stereotopy head waving duration, day 30.10.10.40.50.30.30.20.40.4-0.0-0.2-0.00.10.6-0.2-0.2-0.5-0.50.0-0.1-0.60.60.6
Locomotion velocity, session 70.20.31.50.80.40.30.10.20.00.5-0.10.5-0.4-0.20.20.2-0.1-0.1-0.80.41.21.20.2
Locomotion distance, session 71.52.03.3-0.7-1.2-1.2-1.5-1.0-1.31.81.11.8-1.7-1.01.61.60.70.7-1.81.71.81.70.8
Stereotopy head waving bouts, day 71.31.52.31.31.31.31.31.31.2-1.2-1.2-1.21.21.1-1.2-1.2-1.3-1.31.2-1.2-1.5-1.1-0.1
Stereotopy head waving duration, day 72.42.94.51.91.81.81.71.91.7-1.6-1.8-1.61.61.6-1.6-1.6-2.0-2.11.5-1.6-1.6-1.6-0.8
Locomotion velocity, session 80.50.61.60.0-0.4-0.4-0.6-0.3-0.91.00.51.0-1.0-0.51.31.30.20.1-1.00.91.10.80.7
Locomotion distance, session 80.00.10.2-0.2-0.3-0.3-0.4-0.1-0.20.30.10.4-0.30.10.30.3-0.2-0.2-0.20.30.10.1-0.1
Degree of sensitization distance0.20.20.70.80.50.50.30.60.4-0.1-0.4-0.10.10.7-0.1-0.1-0.6-0.8-0.0-0.2-0.10.4-0.0
Degree of sensitization stereotypy1.61.72.21.51.51.51.51.41.3-1.4-1.4-1.41.41.1-1.3-1.3-1.3-1.41.3-1.3-1.2-1.2-0.6
Conditioned locomotion1.01.11.70.81.01.01.20.91.0-1.3-1.0-1.31.30.9-1.1-1.1-0.7-0.81.3-1.2-1.2-1.2-0.8
Cocaine response after cond. corrected2.52.93.81.71.71.71.61.81.8-1.6-1.9-1.61.71.7-1.7-1.7-1.9-1.81.6-1.6-1.1-1.8-1.9
Cocaine response after cond. not corrected1.82.03.01.71.71.71.61.51.4-1.4-1.5-1.41.41.2-1.2-1.2-1.4-1.31.3-1.4-0.4-0.9-1.6
Cocaine response before conditioning1.01.25.0-0.0-0.2-0.3-0.2-0.8-1.10.71.00.8-0.8-1.31.11.11.41.3-1.10.91.92.21.2
Saline control response2.22.97.0-2.7-2.2-2.1-1.9-2.1-1.81.31.81.4-1.4-2.21.11.12.11.8-1.01.50.40.21.8
Bone: connectivity density0.71.11.71.31.31.21.21.21.1-1.1-1.2-1.01.01.1-1.1-1.1-1.1-1.20.9-1.0-0.6-0.7-0.8
Bone: cortical apparent density0.81.12.5-0.7-0.7-0.8-0.7-1.0-1.00.91.20.9-0.9-1.60.70.71.21.2-1.11.01.11.11.6
Bone: cortical area2.43.76.32.52.42.32.32.12.2-1.9-2.0-1.81.82.0-2.2-2.2-1.7-1.71.5-1.7-0.6-0.1-1.7
Bone: cortical porosity0.30.41.40.00.20.30.30.40.5-0.7-0.5-0.60.60.4-0.8-0.8-0.6-0.50.7-0.6-1.2-0.8-0.0
Bone: cortical porosity0.60.71.70.40.60.60.70.70.8-1.0-0.8-0.90.90.7-1.0-1.0-0.9-0.81.0-0.9-1.3-0.9-0.4
Bone: cortical thickness0.91.43.41.81.61.51.51.31.4-1.0-1.2-0.91.01.0-1.4-1.4-1.1-1.10.6-0.90.10.4-0.8
Bone: cortical thickness0.40.51.21.11.00.91.00.70.8-0.7-0.6-0.50.60.4-0.9-0.9-0.4-0.30.3-0.50.60.6-0.9
Bone: cortical tissue density1.11.43.1-0.8-0.9-0.9-0.9-1.2-1.21.11.31.1-1.1-1.80.80.81.41.4-1.31.11.31.21.6
Condit. Reinf. active minus inactive responses2.93.35.0-2.2-2.0-2.0-1.9-2.1-1.91.72.01.7-1.6-2.21.41.42.02.2-1.51.70.90.72.1
Condit. Reinf. active-inactive response ratio2.22.43.9-1.7-1.6-1.7-1.6-1.7-1.71.51.61.5-1.4-1.91.41.41.61.7-1.31.50.70.42.0
Condit. Reinf. active responses0.60.71.9-1.4-1.1-1.1-0.9-1.1-0.80.71.00.8-0.6-1.00.40.41.01.2-0.50.6-0.0-0.10.9
Condit. Reinf. inactive responses1.21.43.50.40.80.80.90.91.4-1.2-1.0-1.21.41.4-1.5-1.5-0.9-0.91.4-1.4-1.9-1.3-1.0
Incentive salience index mean1.61.92.9-1.7-1.6-1.6-1.4-1.6-1.41.31.51.4-1.2-1.61.01.01.51.7-1.21.20.60.71.6
Condit. Reinf. lever presses0.00.10.5-0.2-0.2-0.1-0.2-0.0-0.00.00.10.10.00.2-0.0-0.0-0.2-0.10.1-0.0-0.7-0.10.5
Condit. Reinf. active minus inactive responses0.10.10.3-0.4-0.2-0.2-0.0-0.20.3-0.10.1-0.10.20.0-0.6-0.60.30.10.2-0.1-0.50.20.3
Condit. Reinf. active-inactive response ratio0.80.81.70.20.40.50.60.61.2-0.9-0.8-0.81.01.1-1.3-1.3-0.8-0.91.0-1.0-1.3-0.9-1.0
Condit. Reinf. active responses0.30.40.9-0.9-0.7-0.8-0.6-0.8-0.50.50.70.5-0.5-0.80.30.31.00.6-0.50.60.20.60.8
Condit. Reinf. inactive responses1.41.83.0-1.3-1.3-1.3-1.2-1.4-1.61.21.41.2-1.3-1.71.31.31.61.3-1.21.41.10.91.6
Condit. Reinf. lever presses0.50.61.5-0.9-0.7-0.7-0.5-1.0-0.80.50.80.5-0.6-1.10.50.51.21.1-0.50.70.70.80.8
Condit. Reinf. lever reinforcers received0.60.81.7-1.3-1.0-1.1-0.9-1.2-0.80.81.00.8-0.8-1.10.40.41.31.0-0.70.80.50.80.9
Conditioned reinforcement - actives7.57.516.5-4.1-3.6-3.5-3.3-3.3-2.82.72.92.8-2.6-2.62.52.52.92.6-2.22.51.40.90.9
Conditioned reinforcement - inactives3.84.36.7-2.6-2.5-2.5-2.5-2.3-2.12.22.12.3-2.2-1.92.12.12.01.8-1.91.91.31.20.8
Conditioned locomotion6.37.618.1-4.2-3.8-3.7-3.5-3.3-3.02.52.92.7-2.6-2.62.52.52.72.4-2.02.51.20.91.0
Patch foraging indifference point 0 sec0.50.91.41.11.11.01.11.01.0-0.9-1.0-0.90.91.2-1.0-1.0-0.9-0.80.8-1.0-0.5-0.2-0.9
Patch foraging indifference point AUC0.20.20.5-0.4-0.4-0.4-0.3-0.5-0.40.50.60.4-0.4-0.40.40.40.70.7-0.60.30.30.60.4
Delay disc. indifference point, 0s delay0.10.10.4-0.3-0.4-0.3-0.4-0.1-0.20.20.20.2-0.2-0.20.10.1-0.3-0.4-0.20.2-0.2-0.60.4
Delay disc. indifference point, 16s delay0.10.10.4-0.2-0.2-0.2-0.1-0.30.00.30.20.2-0.2-0.2-0.0-0.00.70.4-0.30.20.40.30.1
Delay disc. indifference point, 2s delay0.10.11.10.10.10.20.10.20.0-0.2-0.2-0.30.2-0.2-0.3-0.3-0.2-0.20.30.0-0.3-1.10.6
Delay disc. indifference point, 24s delay0.40.40.8-0.9-0.8-0.7-0.7-0.7-0.80.60.60.5-0.6-0.80.60.60.60.5-0.50.60.3-0.20.5
Delay disc. indifference point, 4s delay1.41.42.1-1.2-1.4-1.3-1.4-1.1-1.31.41.31.3-1.3-1.31.21.21.00.8-1.41.21.00.80.9
Delay disc. indifference point, 8s delay0.50.51.0-0.7-0.8-0.7-0.8-0.6-0.80.80.70.7-0.7-1.00.60.60.60.3-0.70.60.50.10.7
Indifference point function ln k0.60.91.71.31.11.11.01.10.9-0.9-1.1-0.80.81.0-0.7-0.7-1.1-1.10.8-0.8-0.2-0.5-1.0
Indifference point function log k0.60.91.71.31.11.11.01.10.9-0.9-1.1-0.80.81.0-0.7-0.7-1.1-1.10.8-0.8-0.2-0.5-1.0
Patch foraging total patch changes 0 sec0.30.50.90.90.90.80.80.80.7-0.5-0.7-0.60.61.0-0.7-0.7-0.7-0.70.5-0.7-0.20.0-0.7
Patch foraging total patch changes 12 sec0.10.20.7-0.2-0.3-0.3-0.3-0.4-0.20.70.50.5-0.50.00.40.40.40.5-0.70.30.40.80.1
Patch foraging total patch changes 18 sec1.51.93.41.51.41.41.31.51.4-1.2-1.4-1.31.21.9-1.0-1.0-1.5-1.71.2-1.5-1.0-1.0-1.8
Patch foraging total patch changes 24 sec0.10.10.5-0.1-0.1-0.0-0.10.20.3-0.0-0.3-0.00.10.7-0.2-0.2-0.5-0.60.2-0.3-0.5-0.4-0.6
Patch foraging total patch changes 6 sec0.50.71.6-0.6-0.7-0.7-0.8-0.8-0.71.00.80.9-0.9-0.70.50.50.70.8-1.10.81.31.30.2
Patch foraging time to switch 0 sec0.10.10.5-0.5-0.4-0.4-0.3-0.4-0.40.20.40.2-0.2-0.40.40.40.40.5-0.10.4-0.00.00.7
Patch foraging water rate 0 sec0.00.10.50.00.00.00.00.10.30.0-0.10.00.10.2-0.5-0.5-0.1-0.20.0-0.20.2-0.0-0.7
Patch foraging water rate 12 sec0.10.10.70.0-0.1-0.0-0.20.30.4-0.1-0.30.10.10.5-0.5-0.5-0.7-0.80.2-0.2-0.5-0.4-0.5
Patch foraging water rate 18 sec0.30.51.2-0.8-1.0-0.9-1.1-0.6-0.31.00.51.1-0.8-0.30.20.20.10.3-0.80.70.50.5-0.1
Patch foraging water rate 24 sec0.00.10.5-0.2-0.1-0.1-0.10.10.0-0.2-0.3-0.10.1-0.0-0.1-0.1-0.2-0.30.30.0-0.0-0.7-0.5
Patch foraging water rate 6 sec0.10.10.4-0.4-0.3-0.2-0.2-0.00.1-0.1-0.1-0.00.10.2-0.2-0.2-0.2-0.30.3-0.2-0.5-0.7-0.7
Seeking ratio, delayed vs. immediate footshock0.50.62.2-0.5-0.6-0.6-0.5-0.8-0.70.50.80.6-0.6-0.90.30.31.01.0-0.70.71.21.50.4
Distance traveled before self-admin3.73.98.3-2.9-2.9-2.7-2.8-2.1-2.22.12.02.1-2.0-1.82.02.01.11.2-1.51.90.8-0.20.9
Distance traveled after self-admin2.83.14.9-2.2-2.2-2.1-2.2-1.9-1.71.91.81.9-1.8-2.01.41.41.41.5-1.71.81.51.01.0
Extensor digitorum longus weight1.14.36.72.12.12.12.12.12.2-1.9-2.3-1.92.02.2-2.2-2.2-2.1-2.11.9-2.0-1.0-1.7-2.6
Bone: elastic displacement0.10.10.30.60.40.30.20.30.10.1-0.20.1-0.10.20.20.2-0.5-0.3-0.2-0.00.00.10.2
Bone: elastic work1.52.03.11.41.41.41.31.51.5-1.3-1.6-1.21.31.6-1.4-1.4-1.8-1.61.3-1.4-1.3-1.2-1.2
Bone: endosteal estimation1.84.06.01.51.71.81.81.92.0-2.1-2.1-2.02.02.3-1.9-1.9-1.9-2.02.2-2.1-1.8-2.2-2.5
Bone: endosteal perimeter1.93.95.01.72.02.02.21.92.1-2.2-2.0-2.22.22.2-2.1-2.1-1.6-1.52.2-2.1-1.9-1.4-1.6
Epididymis fat weight1.43.34.6-2.1-2.1-2.1-2.1-1.9-2.02.01.81.8-1.9-1.81.91.91.81.5-1.61.81.70.70.7
Delta time in closed arm before/after self-admin1.11.01.81.11.11.11.11.11.1-1.0-1.0-1.01.00.8-1.3-1.3-1.1-1.00.9-0.8-0.7-0.8-0.2
Delta time in open arm before/after self-admin0.30.30.60.70.60.60.50.70.3-0.4-0.5-0.50.40.80.10.1-0.7-0.80.4-0.6-0.6-0.3-0.7
Diff in mean of infusions in LGA sessions1.01.11.6-0.7-0.7-0.8-0.7-1.0-1.20.90.90.9-1.0-1.21.21.21.31.2-1.11.21.20.81.3
Delay discount exponential model param0.30.30.70.70.70.60.60.60.6-0.6-0.6-0.50.50.9-0.3-0.3-0.6-0.30.6-0.6-0.40.0-0.7
Extinction: sum of active levers before priming3.53.45.2-1.4-1.6-1.6-1.6-1.8-1.91.81.81.9-1.9-2.01.91.92.11.8-2.02.02.32.11.7
Active lever presses in extinction session 60.60.61.0-0.8-0.8-0.7-0.7-0.8-0.80.80.70.7-0.7-1.00.70.70.90.8-0.60.80.70.50.7
Bone: final force1.21.93.01.51.61.51.61.31.6-1.4-1.4-1.31.41.4-1.7-1.7-1.1-1.11.2-1.4-0.8-0.2-1.1
Bone: final moment1.83.04.51.82.01.92.01.72.0-1.8-1.7-1.71.81.8-2.1-2.1-1.5-1.41.6-1.7-1.1-0.5-1.4
Food consumed during 24 hour testing period0.91.11.80.81.11.11.30.91.0-1.3-1.0-1.41.30.9-1.1-1.1-0.4-0.61.3-1.2-0.8-1.0-0.9
Glucose0.00.10.3-0.4-0.3-0.2-0.1-0.1-0.1-0.30.0-0.30.20.10.00.0-0.1-0.10.4-0.2-0.6-0.2-0.2
Heart weight0.81.21.5-1.0-1.0-1.1-1.1-1.1-1.01.21.21.2-1.1-1.00.80.81.11.2-1.21.21.21.10.8
Delay discount hyperbolic model param0.30.30.70.60.70.60.60.50.6-0.5-0.6-0.40.50.8-0.3-0.3-0.6-0.30.5-0.5-0.40.1-0.7
Intermittent access intake day 1-15 change0.60.62.40.20.50.50.50.60.4-0.8-0.7-0.90.80.5-0.6-0.6-0.8-0.71.0-0.8-1.2-1.6-0.5
Intermittent access intake escalation0.30.32.7-0.3-0.00.00.00.20.1-0.4-0.4-0.60.40.3-0.2-0.2-0.6-0.50.8-0.5-1.2-1.6-0.3
Intermittent access intake escalation 20.10.10.7-0.2-0.0-0.00.00.10.2-0.3-0.3-0.30.30.2-0.3-0.3-0.3-0.30.5-0.3-0.8-0.8-0.2
Intermitt. access day 1 inactive lever presses2.22.44.6-0.9-1.2-1.3-1.4-1.4-1.31.81.51.8-1.7-1.41.51.51.51.4-1.91.62.02.11.0
Intermitt. access day 15 inactive lever presses3.23.55.1-1.6-1.9-1.9-2.0-1.8-1.72.11.82.3-2.1-1.71.91.91.71.8-2.12.01.91.81.5
Intermitt. access escalation Index0.50.40.90.50.50.60.60.70.6-0.6-0.7-0.60.60.5-0.6-0.6-0.8-0.70.7-0.7-0.9-0.9-0.4
Intermittent access day 1 total infusions3.13.66.7-2.6-2.4-2.4-2.3-2.1-2.02.12.02.0-1.9-1.52.12.11.91.7-1.71.60.90.70.3
Intermittent access day 15 total infusions1.82.05.1-2.3-2.0-1.9-1.9-1.6-1.61.51.41.3-1.4-1.01.61.61.11.0-0.91.00.0-0.50.1
Intermittent access terminal intake (last 3 days)3.64.07.5-2.7-2.6-2.6-2.5-2.2-2.12.32.02.2-2.1-1.62.22.21.71.6-1.81.60.80.60.5
Intermittent access total infusions4.75.39.4-3.1-2.9-2.8-2.7-2.6-2.52.52.42.4-2.3-2.02.52.52.32.1-2.01.91.21.10.5
Intermittent access day 1 locomotion5.15.411.0-3.3-3.1-3.0-2.9-2.6-2.42.52.42.4-2.4-1.92.32.32.22.0-1.92.11.10.80.6
Intermittent access day 15 total locomotion4.54.811.3-3.4-3.0-2.9-2.8-2.6-2.22.12.22.2-2.1-2.02.02.02.21.8-1.72.01.00.60.7
Intermittent access total locomotion4.34.912.5-3.5-3.1-3.0-2.9-2.6-2.22.22.32.2-2.1-1.82.02.02.11.9-1.61.80.70.50.3
Intermittent access standard deviation0.30.30.6-0.8-0.6-0.7-0.6-0.7-0.50.50.60.4-0.5-0.60.40.40.70.7-0.50.20.30.8-0.1
Left kidney weight0.10.11.20.30.10.10.00.10.20.2-0.10.2-0.10.0-0.3-0.3-0.0-0.2-0.20.21.10.4-0.9
Right kidney weight0.00.11.00.20.20.10.1-0.00.00.10.00.0-0.1-0.2-0.4-0.40.30.1-0.20.21.00.8-0.5
Cocaine induced anxiety0.10.10.8-0.2-0.2-0.3-0.2-0.3-0.10.10.20.5-0.2-0.20.20.20.50.4-0.30.10.40.9-0.1
Post-drug Anxiety0.00.00.2-0.4-0.4-0.3-0.3-0.2-0.0-0.00.10.4-0.00.00.00.00.10.1-0.0-0.1-0.10.0-0.2
Baseline Anxiety0.30.31.20.30.40.40.40.50.5-0.3-0.4-0.50.50.5-0.6-0.6-0.6-0.60.5-0.4-0.7-1.1-0.3
Tail length2.78.310.42.93.13.13.22.93.0-3.1-3.0-3.13.12.7-3.0-3.0-2.4-2.72.8-3.1-2.1-2.5-2.4
Length with tail0.10.31.40.40.50.50.60.40.7-0.5-0.5-0.50.60.6-0.6-0.6-0.2-0.40.5-0.7-0.1-0.1-1.2
Length without tail2.45.26.5-2.3-2.4-2.5-2.5-2.4-2.32.62.42.5-2.4-1.92.32.32.12.1-2.32.32.32.30.7
Times rat made contact with spout0.40.42.3-1.0-0.8-0.7-0.6-0.4-0.50.10.30.1-0.2-0.20.30.30.00.10.30.2-1.5-1.21.0
Lifetime Intake4.65.210.6-3.3-3.0-2.9-2.8-2.6-2.42.42.42.3-2.2-1.92.32.32.32.1-1.91.81.10.90.5
Liver weight, left0.10.21.3-0.10.10.10.20.10.6-0.3-0.2-0.40.50.6-0.9-0.9-0.1-0.30.4-0.4-0.10.2-1.2
Liver weight, right0.60.95.80.10.40.50.60.60.9-1.0-0.9-1.01.00.8-1.1-1.1-0.6-0.61.1-1.0-0.3-1.0-2.4
Locomotor activity1.42.24.0-2.0-2.0-1.9-2.0-1.6-1.51.61.71.4-1.5-1.41.31.31.31.2-1.31.60.80.21.0
Locomotor testing distance0.81.43.0-1.7-1.7-1.6-1.7-1.2-1.31.21.21.1-1.2-0.91.21.20.60.6-0.91.20.2-0.30.5
Locomotor testing rearing2.43.76.4-2.5-2.4-2.3-2.3-2.1-2.21.82.01.7-1.9-2.01.91.91.71.8-1.52.00.60.21.9
Locomotion in novel chamber0.70.92.5-1.6-1.3-1.3-1.2-1.1-1.20.70.80.7-0.8-0.71.21.20.80.8-0.40.80.0-0.80.3
Locomotion in novel chamber post-restriction1.92.34.1-1.2-1.5-1.4-1.6-1.3-1.71.71.61.8-1.7-1.32.02.01.01.1-1.61.51.31.40.9
Fecal boli incidents, locomotor time 10.20.30.60.10.20.30.40.30.4-0.8-0.5-0.70.60.3-0.7-0.7-0.3-0.50.7-0.5-0.8-0.5-0.5
Change in fecal boli incidents, locomotor task0.80.82.0-0.6-0.6-0.7-0.7-0.9-0.60.90.90.9-0.8-1.00.50.51.11.0-1.00.81.41.40.7
Time >=10cm from walls, locomotor time 10.30.30.50.70.60.60.60.60.6-0.4-0.5-0.30.40.4-0.7-0.7-0.5-0.70.3-0.5-0.20.3-0.2
Bouts of movement, locomotor time 10.20.20.50.0-0.2-0.2-0.3-0.2-0.30.50.30.5-0.5-0.30.40.40.30.4-0.60.50.70.70.5
Total resting periods, locomotor time 10.10.10.2-0.0-0.2-0.2-0.2-0.2-0.10.40.10.3-0.3-0.10.20.20.10.2-0.40.30.30.40.3
Rest time, locomotor task time 10.00.10.20.20.20.20.20.20.1-0.2-0.2-0.20.10.50.10.1-0.2-0.30.2-0.2-0.30.2-0.4
Distance moved, locomotor task time 11.31.41.9-1.2-1.4-1.3-1.4-1.2-1.31.21.31.2-1.2-1.31.11.10.91.0-1.21.41.10.41.1
Vertical activity count, locomotor time 10.20.20.5-0.7-0.6-0.6-0.5-0.6-0.50.40.60.4-0.4-0.50.30.30.60.7-0.30.40.30.00.1
Time >=10cm from walls, locomotor time 21.21.33.4-0.4-0.8-0.7-0.9-0.8-1.21.11.21.1-1.2-1.31.11.10.90.8-1.41.21.61.91.3
Bouts of movement, locomotor time 20.20.20.4-0.2-0.4-0.4-0.5-0.2-0.50.50.40.5-0.6-0.30.60.6-0.10.0-0.50.50.40.20.5
Total resting periods, locomotor time 20.00.00.30.40.20.20.10.30.1-0.0-0.10.0-0.00.20.10.1-0.5-0.4-0.1-0.1-0.10.00.0
Rest time, locomotor task time 20.91.01.81.11.31.11.20.91.2-1.0-1.0-0.91.01.3-1.0-1.0-0.6-0.60.8-1.1-0.60.4-1.3
Distance moved, locomotor task time 23.33.85.5-1.8-2.1-1.9-2.1-1.9-2.22.02.11.9-2.0-2.32.02.01.61.7-2.02.22.01.12.0
Vertical activity count, locomotor time 21.21.31.8-1.2-1.3-1.2-1.3-1.1-1.31.21.31.1-1.2-1.21.31.30.90.9-1.01.21.00.30.9
Light reinforcement 11.93.55.0-2.1-2.2-2.2-2.2-1.9-1.92.11.82.1-2.0-1.81.71.71.51.5-2.01.91.41.31.4
Light reinforcement 20.70.92.0-1.0-0.9-1.0-0.9-1.1-0.61.11.01.0-0.8-1.00.20.21.21.4-1.00.81.11.30.5
Bone: marrow area1.94.26.01.51.81.81.92.02.0-2.1-2.2-2.12.12.3-2.0-2.0-2.0-2.02.3-2.1-1.9-2.3-2.4
Bone: maximum diameter1.42.64.72.22.12.02.01.81.8-1.6-1.7-1.51.61.8-1.7-1.7-1.3-1.41.3-1.4-0.40.0-1.4
Bone: maximum force3.05.27.72.12.42.32.52.22.5-2.5-2.3-2.42.42.3-2.8-2.8-2.0-2.02.3-2.3-1.9-1.4-1.8
Bone: maximum moment3.86.69.62.42.72.62.82.52.9-2.7-2.6-2.72.72.6-3.1-3.1-2.3-2.32.6-2.6-2.2-1.6-2.0
Mean time between licks in bursts0.71.01.5-1.2-1.2-1.2-1.2-1.1-1.11.11.01.1-1.1-1.10.90.90.90.8-1.01.10.50.30.9
Mean num. licks in bursts0.20.31.7-0.10.20.20.30.2-0.0-0.6-0.4-0.70.50.20.00.0-0.2-0.20.8-0.6-0.9-1.3-0.3
Cd content in liver1.31.44.00.40.80.81.00.91.0-1.3-1.0-1.31.30.9-1.4-1.4-0.8-1.11.5-1.3-2.0-1.7-0.3
Co content in liver0.30.40.80.80.80.70.80.50.8-0.5-0.5-0.50.60.4-0.9-0.9-0.2-0.20.3-0.50.50.5-0.8
Cu content in liver0.20.30.90.50.40.40.30.60.6-0.3-0.7-0.30.40.7-0.6-0.6-0.9-0.80.4-0.4-0.3-0.4-0.7
Fe content in liver0.10.10.70.80.50.50.30.40.30.1-0.30.1-0.10.2-0.1-0.1-0.5-0.5-0.30.10.70.5-0.0
K content in liver0.70.71.90.91.00.90.90.90.8-0.8-1.0-0.80.80.7-0.7-0.7-0.9-0.70.7-0.80.0-0.5-1.4
Mg content in liver0.90.91.91.41.31.21.11.11.0-0.8-1.2-0.80.80.8-0.8-0.8-1.1-0.90.6-0.80.4-0.2-1.4
Mn content in liver0.10.10.40.2-0.0-0.1-0.2-0.1-0.30.40.10.4-0.4-0.20.60.60.00.0-0.50.50.70.30.3
Na content in liver0.20.20.50.10.20.30.30.30.3-0.4-0.4-0.40.40.2-0.5-0.5-0.3-0.30.5-0.4-0.2-0.7-0.7
Rb content in liver0.30.40.70.60.70.60.60.60.8-0.5-0.8-0.50.60.6-0.8-0.8-0.9-0.60.5-0.6-0.3-0.3-0.8
Se content in liver2.53.14.2-1.7-2.0-1.9-2.0-1.7-1.92.01.72.0-1.9-1.61.91.91.51.1-1.81.91.71.31.1
Sr content in liver2.82.55.60.91.01.21.11.51.5-1.4-1.6-1.41.51.9-1.5-1.5-1.7-2.01.7-1.5-1.4-2.0-2.4
Zn content in liver4.04.58.02.52.52.42.42.22.3-2.1-2.2-2.12.22.2-2.1-2.1-1.8-1.81.8-2.1-0.3-0.9-2.8
Bone: minimum diameter1.83.44.61.82.01.92.01.82.1-1.9-1.9-1.81.92.0-2.1-2.1-1.7-1.61.8-1.9-1.7-1.2-1.6
Time in familiar zone, hab. session 10.30.21.00.20.40.30.40.30.5-0.4-0.5-0.40.50.3-0.5-0.5-0.4-0.30.5-0.5-0.1-0.9-1.0
Time in novel zone, hab. session 10.30.30.80.90.70.70.70.60.5-0.6-0.4-0.50.50.5-0.4-0.4-0.4-0.40.3-0.5-0.40.60.3
Total zone transitions, hab. session 10.20.20.9-0.10.10.10.20.30.3-0.5-0.3-0.50.50.5-0.3-0.3-0.4-0.20.7-0.5-0.8-1.0-0.6
Total locomotion distance, hab. session 13.65.17.31.51.92.02.12.12.4-2.4-2.1-2.42.52.5-2.4-2.4-2.1-1.92.6-2.5-2.7-2.0-2.1
Locomotion velocity, hab. session 11.82.64.30.81.21.21.41.31.8-1.7-1.4-1.71.81.9-1.8-1.8-1.4-1.31.9-1.8-2.1-1.5-1.7
Time in familiar zone, hab. session 20.90.92.60.10.40.40.50.70.9-0.8-0.9-0.91.01.0-1.0-1.0-0.8-1.01.2-0.9-1.0-1.6-1.6
Time in novel zone, hab. session 20.50.51.70.2-0.1-0.2-0.2-0.3-0.60.60.50.7-0.7-0.70.90.90.50.7-1.00.71.01.31.1
Total zone transitions, hab. session 20.40.51.2-1.1-1.1-1.0-1.0-0.8-0.80.70.80.7-0.7-0.60.70.70.40.5-0.50.7-0.1-0.20.7
Total locomotion distance, hab. session 20.60.82.00.20.50.50.60.71.0-0.9-0.7-1.01.01.0-1.1-1.1-0.8-0.71.2-1.0-1.4-1.2-0.9
Locomotion velocity, hab. session 20.60.82.00.10.40.50.50.60.9-0.9-0.6-0.91.01.0-1.0-1.0-0.7-0.71.2-0.9-1.4-1.3-0.9
Novel to familiar place preference ratio1.01.12.8-0.4-0.7-0.7-0.9-0.8-0.91.10.91.2-1.2-0.71.21.20.70.8-1.31.11.41.70.7
Novelty place preference1.41.43.3-0.6-0.9-1.0-1.1-1.0-1.11.31.11.3-1.3-0.91.31.30.91.0-1.41.31.51.80.9
Time in novel zone, NPP test1.61.63.3-0.8-1.1-1.1-1.2-1.1-1.21.41.21.4-1.4-1.01.41.41.11.1-1.51.41.51.81.0
Total zone transitions, NPP test0.10.11.0-0.3-0.3-0.3-0.3-0.2-0.10.10.30.1-0.1-0.1-0.1-0.1-0.10.00.00.2-0.7-0.11.0
Total locomotion distance, NPP test0.71.02.70.60.80.80.90.81.1-1.1-0.7-1.11.21.0-1.3-1.3-0.8-0.71.1-1.0-1.6-0.6-0.1
Locomotion velocity, NPP test0.40.51.80.50.60.60.70.60.9-0.7-0.4-0.80.80.8-1.0-1.0-0.4-0.40.8-0.7-1.4-0.10.3
Intraocular pressure0.10.20.40.40.50.40.40.40.5-0.2-0.3-0.10.40.5-0.5-0.5-0.3-0.20.3-0.5-0.60.1-0.2
Delta distance traveled before/after self-admin0.10.11.00.30.30.20.30.10.20.00.00.0-0.0-0.2-0.4-0.40.20.1-0.20.10.51.00.2
Delta ambulatory time before/after self-admin0.10.10.50.40.30.30.30.20.30.1-0.10.00.00.1-0.3-0.3-0.0-0.0-0.2-0.10.30.7-0.1
Parametrial fat weight0.10.32.1-0.8-0.5-0.5-0.3-0.6-0.20.10.30.1-0.1-0.30.10.10.80.5-0.0-0.00.70.0-1.4
Pavlov. Cond. lever latency0.10.20.50.70.60.50.40.60.4-0.2-0.6-0.30.20.3-0.2-0.2-0.7-0.60.2-0.20.1-0.4-0.5
Pavlov. Cond. magazine entry latency0.10.20.5-0.6-0.3-0.20.0-0.3-0.1-0.30.3-0.30.3-0.5-0.4-0.40.50.50.3-0.2-0.7-0.50.5
Pavlov. Cond. change in total contacts0.20.20.8-0.7-0.5-0.5-0.4-0.5-0.30.20.60.3-0.2-0.6-0.2-0.20.70.6-0.20.3-0.20.30.9
Pavlov. Cond. index score0.10.10.4-0.7-0.4-0.3-0.1-0.4-0.2-0.10.4-0.10.1-0.3-0.2-0.20.60.50.2-0.1-0.5-0.20.5
Pavlov. Cond. latency score0.20.20.7-0.8-0.5-0.5-0.3-0.6-0.40.00.60.1-0.1-0.5-0.0-0.00.80.7-0.00.1-0.20.10.6
Pavlov. Cond. lever contacts0.10.10.5-0.5-0.2-0.2-0.0-0.10.1-0.30.1-0.20.30.2-0.4-0.40.20.10.4-0.3-0.7-0.4-0.1
Pavlov. Cond. magazine entry number0.10.20.50.60.40.40.20.40.2-0.1-0.4-0.10.00.60.20.2-0.5-0.5-0.0-0.10.40.4-0.7
Pavlov. Cond. intertrial magazine entries0.70.81.21.01.01.01.01.00.9-0.8-1.0-0.90.90.8-1.0-1.0-1.0-0.80.8-0.8-0.3-1.1-1.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.6-0.3-0.3-0.1-0.3-0.1-0.20.3-0.10.2-0.2-0.3-0.30.50.40.2-0.1-0.6-0.20.5
Pavlov. Cond. response bias0.30.41.7-0.20.10.20.40.20.4-0.7-0.3-0.60.70.2-0.8-0.8-0.1-0.20.8-0.7-1.3-1.10.1
Pavlov. Cond. lever latency0.50.61.70.70.60.70.60.80.7-0.7-0.9-0.70.70.9-0.6-0.6-1.1-1.00.7-0.8-0.7-1.3-1.0
Pavlov. Cond. magazine entry latency1.51.84.6-0.8-0.8-1.0-0.8-1.3-1.11.21.51.2-1.2-1.31.11.11.71.7-1.41.21.12.21.9
Pavlov. Cond. change in total contacts1.62.14.4-1.3-1.1-1.3-1.0-1.6-1.41.31.61.3-1.3-1.71.11.12.02.1-1.41.31.52.01.4
Pavlov. Cond. index score2.43.15.7-1.5-1.4-1.5-1.4-1.9-1.71.61.91.6-1.6-1.91.51.52.32.2-1.81.71.72.42.0
Pavlov. Cond. latency score2.63.25.9-1.4-1.4-1.5-1.3-1.9-1.71.62.01.7-1.6-1.91.51.52.32.2-1.81.71.62.42.2
Pavlov. Cond. lever contacts1.01.32.9-1.1-1.0-1.0-0.9-1.2-1.11.01.31.1-1.0-1.30.80.81.51.4-1.11.11.21.71.1
Pavlov. Cond. magazine entry number4.35.37.22.02.12.22.02.42.2-2.3-2.5-2.32.32.4-2.1-2.1-2.7-2.62.4-2.3-2.1-2.6-2.3
Pavlov. Cond. intertrial magazine entries0.30.42.30.30.30.40.30.60.5-0.5-0.8-0.50.50.6-0.5-0.5-1.0-0.60.6-0.6-0.3-1.2-1.5
Pavlov. Cond. lever-magazine prob. diff.2.73.46.4-1.5-1.5-1.6-1.4-2.0-1.71.72.01.7-1.7-2.01.51.52.42.3-1.91.81.82.52.1
Pavlov. Cond. response bias1.52.04.4-1.2-1.2-1.3-1.2-1.5-1.31.41.61.4-1.3-1.41.11.11.71.7-1.41.41.42.11.3
Time in closed arm before self-admin0.10.10.2-0.1-0.3-0.3-0.4-0.1-0.30.40.00.5-0.4-0.30.40.4-0.1-0.2-0.40.20.10.10.3
Time in closed arm after self-admin0.50.51.00.90.70.80.60.90.8-0.5-0.8-0.40.60.5-0.9-0.9-1.0-0.90.4-0.6-0.4-0.2-0.1
Time in open arm before self-admin0.50.61.2-1.0-0.8-0.8-0.7-0.9-0.80.60.90.5-0.7-0.80.70.71.11.1-0.60.70.60.30.5
Time in open arm after self-admin0.60.61.7-0.5-0.5-0.6-0.6-0.7-0.90.80.80.7-0.9-0.51.31.31.00.7-0.70.60.80.80.1
Bone: periosteal estimation3.16.38.62.52.72.62.72.52.7-2.6-2.7-2.52.62.7-2.7-2.7-2.3-2.32.5-2.5-1.5-1.6-2.9
Bone: periosteal perimeter2.54.26.42.22.52.32.52.02.4-2.2-2.0-2.12.22.1-2.5-2.5-1.5-1.41.9-2.1-1.3-0.4-1.4
Bone: post-yield work2.23.05.51.11.61.61.81.51.7-2.1-1.5-2.01.91.7-1.9-1.9-1.2-1.42.1-1.8-2.3-1.8-0.8
Progressive ratio test 1 active lever presses2.72.95.9-2.4-2.2-2.1-2.0-2.0-1.91.61.81.7-1.6-1.71.61.61.81.7-1.41.31.01.00.2
Progressive ratio test 1 breakpoint3.23.36.4-2.5-2.3-2.2-2.1-2.1-2.01.72.01.7-1.7-1.91.71.72.01.9-1.51.31.21.30.3
Progressive ratio test 1 inactive lever presses1.81.93.3-1.7-1.8-1.7-1.8-1.4-1.21.71.41.8-1.6-0.91.41.41.11.0-1.51.20.91.10.2
Progressive ratio test 2 active lever presses5.15.511.3-3.4-2.9-2.9-2.6-2.8-2.52.32.52.2-2.2-2.32.22.22.82.6-1.92.01.30.70.8
Progressive ratio test 2 breakpoint4.04.59.3-3.0-2.6-2.6-2.3-2.6-2.22.12.31.9-2.0-2.11.91.92.62.5-1.71.81.20.70.7
Progressive ratio test 2 inactive lever presses2.73.15.7-2.4-2.2-2.2-2.1-2.0-1.81.91.81.9-1.8-1.71.71.71.91.7-1.61.51.11.00.5
Incentive Sensitization - Responses2.32.34.0-1.9-1.5-1.7-1.4-1.8-1.61.51.61.3-1.4-1.51.61.62.02.0-1.21.51.00.21.0
Incentive Sensitization - Breakpoint2.12.13.5-1.8-1.5-1.6-1.4-1.7-1.51.51.51.3-1.4-1.41.51.51.81.9-1.21.41.00.21.0
Sum of active levers in priming session hrs 5-60.80.81.2-1.1-1.0-1.0-1.0-1.0-1.00.90.90.8-0.8-1.10.70.71.00.9-0.70.90.70.30.9
Progressive ratio0.20.30.90.90.90.70.80.50.5-0.3-0.3-0.40.40.4-0.4-0.4-0.2-0.10.2-0.50.10.6-0.3
Food seeking constrained by brief footshock1.31.62.8-0.8-1.2-1.1-1.3-1.0-1.21.41.11.7-1.5-1.01.41.40.90.8-1.71.21.41.50.9
Seeking ratio, punishment vs. effort1.41.73.0-1.5-1.7-1.6-1.7-1.3-1.41.31.21.5-1.4-1.21.41.41.00.8-1.31.41.00.60.9
Retroperitoneal fat weight0.62.13.7-1.9-1.9-1.8-1.9-1.5-1.61.51.51.5-1.5-1.21.61.61.11.0-1.21.31.10.00.1
Reaction time number correct2.02.85.7-1.1-1.5-1.5-1.8-1.4-1.32.31.52.2-2.0-1.31.41.41.31.2-2.31.72.42.20.5
Reaction time mean minus median0.20.20.60.20.50.40.7-0.00.2-0.60.0-0.70.5-0.2-0.4-0.40.70.70.4-0.50.30.1-0.4
Reaction time mean minus median AUC0.70.91.80.61.00.91.20.60.9-1.3-0.7-1.31.20.5-1.1-1.1-0.0-0.11.1-1.1-0.2-0.6-1.3
Reaction time num false alarms2.63.65.8-1.7-2.0-1.9-2.1-1.8-2.12.21.92.1-2.2-1.42.42.41.41.3-2.11.91.61.40.9
Reaction time num false alarms AUC2.53.45.9-1.5-1.8-1.8-2.0-1.7-2.02.21.92.1-2.2-1.32.42.41.41.3-2.11.81.91.60.5
Reaction time trials correct on left2.02.85.7-1.1-1.5-1.5-1.8-1.4-1.32.31.52.2-2.0-1.31.41.41.31.2-2.31.72.42.20.5
Reaction time trials on left2.13.05.8-1.1-1.6-1.6-1.8-1.5-1.42.31.62.2-2.0-1.41.41.41.31.3-2.31.72.42.30.5
Reaction time mean1.41.94.2-1.0-1.0-1.1-0.9-1.5-1.41.01.51.1-1.2-1.81.21.22.02.0-1.21.41.51.61.7
Reaction time mean AUC1.11.43.5-0.9-0.7-0.8-0.6-1.3-1.20.81.30.8-0.9-1.61.01.01.81.9-1.01.11.41.31.5
Median of all reaction times2.53.45.7-1.4-1.4-1.5-1.4-1.9-1.91.61.91.7-1.7-2.21.71.72.22.4-1.91.92.12.02.0
Reaction time omissions1.21.73.4-1.1-1.0-1.2-1.0-1.4-1.31.21.41.1-1.2-1.51.31.31.71.8-1.21.11.21.31.2
Reaction time false alarm rate0.81.12.7-1.2-1.2-1.2-1.2-1.1-1.41.01.11.0-1.1-0.71.61.60.90.8-0.81.00.50.30.4
Reaction time premature initiation rate0.71.01.5-0.8-1.0-1.0-1.1-0.9-1.01.10.91.2-1.1-1.10.90.90.50.8-1.11.21.20.70.7
Reaction time premature initiations2.33.35.5-1.4-1.8-1.8-2.0-1.6-1.62.21.62.2-2.1-1.81.61.61.21.5-2.22.02.32.01.0
Std. dev. reaction times0.40.62.5-0.5-0.2-0.4-0.1-0.8-0.70.20.80.2-0.3-1.00.50.51.51.6-0.40.40.91.00.6
Reaction time trials completed2.13.05.8-1.1-1.6-1.6-1.8-1.5-1.42.31.62.2-2.0-1.41.41.41.31.3-2.31.72.42.30.5
Reaction time trials AUC2.23.25.8-1.2-1.6-1.7-1.9-1.5-1.52.41.72.3-2.1-1.41.51.51.41.3-2.41.82.42.40.7
Run reversals in cocaine runway, females0.10.10.30.00.0-0.1-0.0-0.1-0.20.30.20.1-0.30.10.60.60.20.1-0.20.10.20.3-0.1
Run reversals in cocaine runway, males5.25.16.62.12.32.32.52.22.5-2.5-2.2-2.32.52.2-2.6-2.6-1.9-2.02.3-2.4-2.0-1.3-1.8
Latency to leave start box in cocaine runway0.40.41.50.70.40.50.30.80.6-0.4-0.7-0.30.41.0-0.3-0.3-1.2-1.20.4-0.5-0.8-0.7-0.5
Latency to leave start box in cocaine runway, F0.10.10.30.2-0.1-0.1-0.3-0.1-0.10.50.20.5-0.5-0.10.40.4-0.1-0.0-0.60.50.50.50.4
Latency to leave start box in cocaine runway, M1.81.73.90.70.81.00.91.31.1-1.2-1.3-1.21.31.5-1.0-1.0-1.6-1.71.5-1.4-1.9-2.0-1.2
Std. dev. time between licks in bursts0.30.31.3-1.1-0.9-0.8-0.7-0.8-0.60.30.60.4-0.4-0.60.40.40.70.7-0.20.5-0.1-0.20.3
Total sessions with >9 infusions1.92.06.7-2.6-2.2-2.1-2.0-1.8-1.41.41.41.3-1.2-1.21.11.11.41.2-0.81.00.1-0.3-0.1
Short access day 1 total inactive lever presses6.67.39.6-2.6-2.8-2.8-2.9-2.7-2.73.12.73.1-3.0-2.53.03.02.62.5-2.92.72.41.91.8
Short access day 10 total inactive lever presses2.02.25.9-0.6-0.9-1.1-1.1-1.3-1.01.61.21.7-1.6-1.31.31.31.61.6-1.91.72.22.41.4
Short access day 1 total infusions3.74.09.1-3.0-2.6-2.6-2.4-2.4-1.91.92.11.9-1.8-2.01.61.62.32.1-1.51.81.00.70.7
Short access day 10 total infusions2.83.16.9-2.6-2.3-2.3-2.2-2.1-1.91.71.81.7-1.7-1.51.71.71.81.6-1.41.40.80.90.3
Short access total infusions2.42.77.4-2.7-2.4-2.3-2.1-2.0-1.81.61.71.5-1.5-1.41.51.51.71.5-1.11.20.50.10.1
Short access day 1 locomotion5.35.613.8-3.7-3.3-3.2-3.0-2.9-2.52.22.52.2-2.2-2.42.02.02.52.3-1.72.01.20.70.6
Short access day 10 total locomotion2.32.67.3-2.7-2.4-2.3-2.2-1.9-1.71.61.71.5-1.5-1.41.51.51.31.3-1.11.30.30.20.1
Short access total locomotion6.76.915.9-4.0-3.6-3.5-3.3-3.1-2.92.62.72.5-2.5-2.62.42.42.62.5-2.02.21.20.90.6
One hour access (0.3 mA shock)0.50.52.5-1.6-1.2-1.2-1.0-1.0-0.50.50.70.7-0.5-0.40.30.31.00.6-0.30.4-0.2-0.1-0.4
Compulsive drug intake0.80.82.01.01.01.01.00.81.3-0.8-0.9-0.91.00.5-1.4-1.4-0.5-0.50.7-0.7-0.2-0.2-0.1
One hour access (shock baseline)3.94.57.8-2.8-2.6-2.6-2.5-2.4-2.32.02.22.2-2.1-2.02.22.22.21.9-1.81.91.31.40.7
Social response proportion1.01.12.7-1.3-1.1-1.1-0.9-1.3-1.20.81.20.9-0.8-1.10.80.81.41.6-0.70.80.30.71.3
Social responses1.31.72.5-1.5-1.3-1.4-1.2-1.5-1.41.11.61.1-1.2-1.21.31.31.51.5-1.01.10.31.11.5
Social time1.21.62.7-1.1-1.0-1.1-1.0-1.3-1.51.21.31.0-1.2-1.51.61.61.41.6-1.11.31.20.61.3
Soleus weight3.18.910.02.82.93.03.03.13.0-3.1-3.1-3.03.13.1-2.9-2.9-3.1-3.23.0-3.1-2.5-2.9-3.0
Bone: stiffness0.91.53.11.01.31.21.41.01.4-1.4-1.0-1.41.41.0-1.8-1.8-0.7-0.81.3-1.2-1.1-0.6-0.7
Tibialis anterior weight0.72.26.41.21.41.31.41.41.5-1.4-1.6-1.51.51.7-1.5-1.5-1.4-1.41.6-1.4-0.6-1.6-2.5
Time to tail flick, vehicle, before self-admin0.10.10.30.30.30.30.30.30.3-0.5-0.4-0.40.40.4-0.2-0.2-0.4-0.20.5-0.5-0.6-0.6-0.2
Time to tail flick, vehicle, after self-admin0.10.10.60.40.20.10.10.10.20.4-0.00.3-0.20.20.20.20.00.1-0.40.10.30.8-0.0
Time to tail flick, test, before self-admin0.20.20.6-0.2-0.5-0.4-0.6-0.1-0.30.50.10.6-0.50.20.50.5-0.5-0.4-0.40.2-0.3-0.80.1
Time to tail flick, test, after self-admin0.70.82.11.00.70.80.51.10.9-0.6-0.9-0.50.71.1-0.8-0.8-1.3-1.40.6-0.7-0.9-0.9-0.4
Delta time to tail flick, vehicle, before/after SA0.20.20.90.1-0.0-0.1-0.1-0.2-0.10.60.30.5-0.4-0.30.30.30.40.4-0.60.50.71.00.2
Delta time to tail flick, test, before/after SA0.40.30.60.70.70.70.60.60.8-0.6-0.5-0.60.60.3-0.8-0.8-0.4-0.60.5-0.5-0.10.1-0.1
Tibia length5.214.627.1-3.0-3.3-3.5-3.6-3.7-3.84.03.54.0-4.0-3.84.14.13.93.8-4.14.05.24.21.7
Ambulatory time before self-admin2.22.35.8-2.4-2.3-2.1-2.2-1.7-1.71.51.51.5-1.4-1.51.31.30.91.0-1.01.30.4-0.30.6
Ambulatory time after self-admin2.42.65.2-2.3-2.2-2.1-2.1-1.8-1.71.71.71.6-1.5-1.81.31.31.41.5-1.31.51.00.60.8
Bone: tissue strength1.01.05.40.20.30.40.30.80.8-0.6-0.8-0.70.71.1-0.8-0.8-1.3-1.41.0-0.7-2.3-1.50.4
Total heroin consumption6.17.19.3-2.2-2.5-2.4-2.5-2.6-3.02.82.82.6-2.7-3.12.72.72.62.6-2.82.72.92.82.3
Bone: trabecular number0.40.71.71.21.01.00.81.10.7-0.6-1.0-0.60.60.9-0.4-0.4-1.2-1.30.6-0.6-0.4-0.7-0.4
Bone: trabecular spacing0.30.41.3-0.3-0.4-0.4-0.5-0.5-0.50.70.70.6-0.6-0.40.70.70.60.8-0.70.60.61.10.7
Bone: trabecular thickness0.00.00.2-0.00.0-0.00.1-0.2-0.1-0.00.10.1-0.1-0.4-0.0-0.00.40.3-0.10.00.10.30.5
Bone: trabecular tissue density0.40.51.20.80.70.70.60.80.8-0.5-0.6-0.60.60.7-0.7-0.7-1.1-0.90.6-0.6-1.0-0.4-0.0
Water consumed over 24 hours0.10.10.3-0.4-0.4-0.4-0.5-0.3-0.40.30.30.4-0.4-0.20.50.50.20.3-0.30.30.2-0.10.0
Number of responses in last shaping day0.30.31.50.40.40.30.30.50.5-0.1-0.5-0.10.31.20.10.1-0.6-0.70.3-0.7-0.6-0.6-1.0