Hub : Genes

Ankrd24

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr7_8063190_8065278 0.02 0.02 1.0e-03 0.02 0.02 0.01 0.02 5.4e-03 2.2e-03 1.7e-02 4.6e-03
2 NAcc isoform ratio XM_039078671.1 0.02 0.01 7.3e-03 0.01 0.01 0 0 5.9e-02 2.9e-02 1.0e-01 7.5e-02
3 BLA gene expression Ankrd24 0.24 0.14 1.1e-09 0.16 0.18 0.19 0.19 4.5e-09 6.3e-10 1.2e-10 2.5e-10
4 Brain isoform ratio XM_039078671.1 0.03 0.02 4.4e-03 0.02 0.01 0.01 0.01 5.7e-03 1.6e-02 3.9e-02 1.4e-02
5 Brain isoform ratio XM_039078672.1 0.03 0.02 5.8e-03 0.02 0.01 0.01 0.01 9.7e-03 2.6e-02 5.5e-02 3.1e-02
6 BLA mRNA stability Ankrd24 0.07 0.06 4.9e-03 0.03 0.02 0.01 0.02 6.8e-03 2.9e-02 6.6e-02 1.9e-02
7 Liver alternative polyA XM_039078672.1 0.03 0.02 4.1e-03 0.01 0.01 0 0.01 9.3e-03 3.8e-02 1.7e-01 3.1e-02
8 Liver alternative polyA NM_001106771.1 0.03 0.03 1.8e-03 0.02 0.01 0.01 0.01 4.1e-03 1.2e-02 8.5e-03 1.4e-02
9 Liver mRNA stability Ankrd24 0.03 0.03 2.0e-03 0.02 0.01 0.01 0.02 9.4e-04 9.3e-03 2.8e-02 6.5e-03
10 pVTA gene expression Ankrd24 0.31 0.14 7.9e-12 0.24 0.25 0.25 0.25 1.2e-10 2.2e-11 2.2e-11 2.2e-11
11 NAcc gene expression Ankrd24 0.2 0.12 0.0e+00 0.13 0.17 0.16 0.16 5.3e-15 5.5e-19 7.9e-18 9.7e-18
12 OFC gene expression Ankrd24 0.31 0.17 3.8e-05 0.21 0.16 0.22 0.2 8.5e-06 1.1e-04 6.6e-06 2.0e-05
13 PL gene expression Ankrd24 0.31 0.15 0.0e+00 0.21 0.26 0.26 0.26 2.4e-22 6.5e-29 1.1e-28 2.9e-28
14 Adipose gene expression Ankrd24 0.09 0.06 5.3e-08 0.03 0.06 0.06 0.05 1.9e-04 7.8e-07 5.3e-07 1.1e-06
15 Brain gene expression Ankrd24 0.32 0.16 0.0e+00 0.14 0.21 0.22 0.22 2.9e-13 3.3e-19 5.3e-20 7.1e-20
16 Liver gene expression Ankrd24 0.07 0.05 1.1e-05 0.03 0.04 0.05 0.04 3.2e-04 8.5e-06 5.7e-06 1.2e-05
17 Adipose mRNA stability Ankrd24 0.08 0.05 3.0e-06 0.05 0.05 0.04 0.05 7.2e-06 4.4e-06 1.7e-05 7.6e-06
18 LHb gene expression Ankrd24 0.2 0.14 5.3e-03 0.01 0.04 0.04 0.04 1.7e-01 4.0e-02 4.4e-02 3.5e-02
19 Brain mRNA stability Ankrd24 0.06 0.05 8.5e-04 0.03 0.03 0.03 0.03 8.2e-04 5.4e-04 1.0e-03 7.8e-04
20 PL mRNA stability Ankrd24 0.08 0.06 3.0e-06 0.01 0.04 0.04 0.03 6.5e-02 1.3e-05 4.3e-05 2.1e-04
21 pVTA mRNA stability Ankrd24 0.1 0.07 8.4e-03 0.02 0.02 0 0.01 3.0e-02 3.3e-02 2.4e-01 8.8e-02
22 Liver isoform ratio XM_039078671.1 0.05 0.04 7.1e-04 0.03 0.03 0.03 0.03 2.3e-04 3.8e-04 2.8e-04 2.9e-04
23 Liver isoform ratio XM_039078672.1 0.05 0.04 6.2e-04 0.03 0.03 0.03 0.03 1.9e-04 3.2e-04 2.7e-04 2.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density2.13.67.0-0.00.0-1.9-1.61.6-0.5-0.50.6-0.62.02.2-2.12.3-2.2-2.4-2.41.52.61.92.2-2.6-2.62.6
Area under the delay curve1.21.22.71.5-1.50.81.2-1.2-1.6-1.61.6-1.6-0.7-0.60.9-0.50.50.60.31.6-0.31.51.4-0.4-0.40.4
BMI with tail3.912.722.44.7-4.73.84.3-4.3-4.6-4.64.5-4.5-3.7-3.43.8-3.13.23.22.63.7-2.63.12.50.80.8-0.8
BMI without tail1.73.55.62.2-2.22.22.4-2.4-2.0-2.01.9-1.9-2.3-2.12.3-2.02.02.11.81.3-1.80.90.61.01.0-1.0
Body weight0.83.35.42.3-2.32.12.3-2.3-2.2-2.22.1-2.1-1.9-1.92.1-1.71.71.81.51.8-1.51.41.10.60.6-0.6
Weight adjusted by age0.40.51.00.6-0.60.80.8-0.8-0.4-0.40.4-0.4-1.0-0.90.8-0.91.00.90.8-0.0-0.8-0.2-0.30.70.7-0.7
Bone surface4.68.115.1-0.50.5-3.1-2.52.5-0.3-0.30.3-0.33.33.5-3.23.6-3.5-3.6-3.71.73.92.42.9-3.9-3.93.9
Bone volume4.88.215.1-0.50.5-3.2-2.62.6-0.3-0.20.3-0.33.33.5-3.33.6-3.5-3.7-3.71.73.92.42.9-3.9-3.93.9
Breakpoint value in progressive ratio session2.93.27.1-2.52.5-1.4-2.02.02.52.4-2.72.71.21.1-1.60.9-1.0-1.1-0.7-2.40.7-2.2-2.00.40.4-0.4
Number of licking bursts0.70.81.90.2-0.21.10.3-0.3-0.0-0.0-0.20.2-1.2-1.20.6-1.31.20.91.3-0.5-1.1-0.8-0.91.41.4-1.4
Context. condit. distance diff. score0.30.40.90.7-0.70.60.9-0.9-0.7-0.70.5-0.5-0.6-0.60.9-0.60.50.70.50.5-0.60.30.30.20.2-0.2
Locomotion velocity, session 11.11.22.6-0.80.8-1.5-0.50.50.60.6-0.50.51.61.6-0.81.6-1.6-1.1-1.60.01.20.30.6-1.4-1.41.4
Locomotion distance, session 11.11.43.4-0.30.3-1.5-0.20.2-0.0-0.00.1-0.11.51.6-0.71.7-1.6-1.1-1.70.71.41.11.3-1.8-1.81.8
Locomotion velocity, session 24.04.68.0-2.02.0-2.8-2.12.11.71.7-1.61.62.82.8-2.42.8-2.8-2.5-2.7-0.72.5-0.10.3-2.1-2.12.1
Locomotion distance, session 22.33.26.3-1.41.4-2.4-1.31.31.01.0-1.01.02.52.5-1.72.5-2.4-2.0-2.4-0.12.10.40.8-2.1-2.12.1
Locomotion velocity, session 33.64.27.7-2.82.8-2.0-2.42.42.82.8-2.72.71.91.8-2.11.6-1.6-1.7-1.3-2.41.3-2.0-1.7-0.2-0.20.2
Locomotion distance, session 30.00.00.1-0.10.10.10.0-0.00.20.2-0.10.1-0.1-0.10.1-0.10.10.10.2-0.3-0.2-0.3-0.30.20.2-0.2
Stereotopy head waving bouts, day 33.33.95.8-2.42.4-2.3-2.42.42.22.2-2.22.22.22.1-2.32.0-2.0-2.1-1.9-1.61.8-1.2-0.9-1.0-1.01.0
Stereotopy head waving duration, day 33.54.26.9-2.62.6-2.3-2.42.42.52.5-2.52.52.22.1-2.22.0-2.0-2.0-1.8-1.91.7-1.5-1.2-0.8-0.80.8
Locomotion velocity, session 70.70.81.5-1.00.9-1.1-1.21.20.90.9-0.80.81.01.0-1.21.0-1.0-1.1-0.9-0.51.0-0.3-0.2-0.6-0.60.6
Locomotion distance, session 70.30.40.80.2-0.20.70.4-0.4-0.0-0.00.1-0.1-0.8-0.80.6-0.80.80.70.9-0.4-0.8-0.5-0.60.90.9-0.9
Stereotopy head waving bouts, day 70.70.82.00.0-0.0-0.9-0.10.1-0.3-0.30.3-0.31.01.1-0.51.2-1.2-0.9-1.30.81.01.01.2-1.4-1.41.4
Stereotopy head waving duration, day 71.11.32.7-0.30.3-1.3-0.70.70.00.0-0.10.11.41.5-1.01.5-1.5-1.3-1.60.61.40.91.1-1.7-1.71.7
Locomotion velocity, session 81.72.14.3-0.60.6-1.8-0.90.90.20.2-0.30.31.91.9-1.32.0-2.0-1.6-2.10.61.81.01.2-2.0-2.02.0
Locomotion distance, session 80.20.20.5-0.30.3-0.70.0-0.00.20.2-0.20.20.70.7-0.20.7-0.7-0.4-0.70.10.50.30.3-0.7-0.70.7
Degree of sensitization distance0.20.20.50.7-0.70.50.5-0.5-0.7-0.70.6-0.6-0.4-0.40.4-0.40.30.30.30.6-0.30.50.40.00.0-0.0
Degree of sensitization stereotypy1.21.33.31.5-1.50.31.1-1.1-1.6-1.61.6-1.6-0.2-0.10.60.1-0.10.2-0.31.80.11.81.8-1.0-1.01.0
Conditioned locomotion2.32.74.61.4-1.42.11.7-1.7-1.1-1.11.1-1.1-2.1-2.11.9-2.12.12.02.10.3-1.9-0.1-0.41.61.6-1.6
Cocaine response after cond. corrected5.15.79.82.4-2.42.93.1-3.1-2.1-2.12.0-2.0-2.9-2.83.1-2.82.82.92.61.2-2.70.60.21.81.8-1.8
Cocaine response after cond. not corrected5.66.210.32.5-2.53.13.2-3.2-2.1-2.12.1-2.1-3.0-3.03.2-2.92.93.12.71.2-2.80.60.11.91.9-1.9
Cocaine response before conditioning0.50.61.3-0.80.8-0.9-1.11.10.70.7-0.60.60.90.9-1.10.9-0.9-1.0-0.8-0.40.9-0.2-0.1-0.6-0.60.6
Saline control response0.10.20.30.2-0.20.50.5-0.5-0.1-0.10.2-0.2-0.5-0.50.6-0.50.50.60.5-0.1-0.6-0.2-0.20.50.5-0.5
Bone: connectivity density1.21.93.90.4-0.4-1.1-0.80.8-0.8-0.81.0-1.01.21.4-1.21.5-1.4-1.5-1.61.51.71.81.9-2.0-2.02.0
Bone: cortical apparent density0.81.01.91.3-1.31.11.4-1.4-1.4-1.41.0-1.0-1.0-0.91.2-0.90.81.00.71.1-0.80.90.70.20.2-0.2
Bone: cortical area0.81.23.40.9-1.0-0.4-0.20.2-1.3-1.31.1-1.10.50.6-0.50.7-0.7-0.8-0.91.71.01.81.8-1.4-1.41.4
Bone: cortical porosity0.70.81.4-0.80.7-1.1-1.11.10.60.6-0.60.61.01.0-1.21.0-1.1-1.1-1.0-0.21.1-0.00.1-0.8-0.80.8
Bone: cortical porosity0.70.71.3-0.10.1-0.9-0.70.7-0.2-0.10.1-0.10.91.0-0.91.0-1.0-1.1-1.10.61.10.80.9-1.2-1.21.2
Bone: cortical thickness0.71.12.71.5-1.50.60.8-0.8-1.6-1.61.5-1.5-0.5-0.40.5-0.20.20.20.11.6-0.01.61.5-0.6-0.60.6
Bone: cortical thickness0.30.30.7-0.10.10.50.2-0.20.30.3-0.30.3-0.6-0.60.4-0.70.70.60.7-0.5-0.7-0.7-0.70.80.8-0.8
Bone: cortical tissue density0.60.81.51.1-1.10.91.2-1.2-1.2-1.20.8-0.8-0.9-0.81.1-0.80.70.90.60.9-0.80.70.60.20.2-0.2
Condit. Reinf. active minus inactive responses2.52.85.0-2.22.2-1.8-1.91.92.22.2-2.22.21.71.6-1.71.5-1.5-1.5-1.3-1.71.2-1.4-1.2-0.4-0.40.4
Condit. Reinf. active-inactive response ratio1.21.32.8-1.61.6-0.8-1.21.21.71.7-1.71.70.70.6-0.90.4-0.5-0.5-0.2-1.70.3-1.6-1.50.50.5-0.5
Condit. Reinf. active responses2.93.65.4-2.12.1-2.3-2.22.21.91.9-1.91.92.32.2-2.22.1-2.1-2.1-2.0-1.21.9-0.8-0.4-1.3-1.31.3
Condit. Reinf. inactive responses1.51.83.2-0.90.9-1.7-1.41.40.70.7-0.70.71.71.7-1.61.7-1.7-1.7-1.80.01.70.40.6-1.5-1.51.5
Incentive salience index mean1.92.33.6-1.61.6-1.9-1.71.71.41.4-1.51.51.91.8-1.81.8-1.8-1.7-1.7-0.81.6-0.5-0.2-1.1-1.11.1
Condit. Reinf. lever presses1.41.94.1-0.10.1-1.5-0.80.8-0.3-0.30.2-0.21.61.6-1.21.7-1.7-1.6-1.91.01.81.41.6-2.0-2.02.0
Condit. Reinf. active minus inactive responses1.51.84.1-1.81.8-0.7-1.51.51.91.9-1.91.90.50.4-1.00.2-0.2-0.5-0.0-2.00.2-2.0-1.90.80.8-0.8
Condit. Reinf. active-inactive response ratio1.11.12.6-0.40.40.90.2-0.20.70.7-0.70.7-1.0-1.10.6-1.21.21.01.3-1.2-1.2-1.4-1.61.61.6-1.6
Condit. Reinf. active responses1.52.14.0-1.91.9-1.3-2.02.01.91.9-1.91.91.31.1-1.71.0-1.0-1.3-0.8-1.71.0-1.4-1.3-0.0-0.00.0
Condit. Reinf. inactive responses1.31.62.7-1.31.3-1.5-1.61.61.11.1-1.11.11.51.5-1.61.4-1.4-1.5-1.3-0.71.4-0.4-0.2-0.9-0.90.9
Condit. Reinf. lever presses1.41.94.1-1.91.9-0.9-1.61.62.02.0-2.02.00.80.7-1.20.5-0.5-0.7-0.3-2.00.4-1.9-1.80.60.6-0.6
Condit. Reinf. lever reinforcers received1.11.63.2-1.71.7-1.0-1.71.71.81.8-1.71.70.90.8-1.30.6-0.6-0.9-0.4-1.70.6-1.5-1.40.30.3-0.3
Conditioned reinforcement - actives1.91.93.0-1.71.7-1.5-1.71.71.61.6-1.71.71.41.4-1.61.3-1.2-1.4-1.2-1.31.2-1.0-0.8-0.5-0.50.5
Conditioned reinforcement - inactives1.31.52.60.9-0.91.61.4-1.4-0.6-0.60.6-0.6-1.5-1.61.5-1.61.51.51.60.2-1.6-0.2-0.51.31.3-1.3
Conditioned locomotion5.06.010.7-3.33.3-2.5-3.03.03.23.2-3.23.22.32.1-2.61.9-1.9-2.1-1.7-2.71.7-2.3-2.0-0.3-0.30.3
Patch foraging indifference point 0 sec0.10.20.40.5-0.50.30.4-0.4-0.6-0.50.6-0.6-0.2-0.30.3-0.20.20.20.10.6-0.10.50.5-0.1-0.10.1
Patch foraging indifference point AUC0.60.71.4-1.21.2-0.9-1.01.01.11.2-1.21.20.70.7-0.80.6-0.6-0.6-0.5-1.10.5-0.9-0.8-0.0-0.00.0
Delay disc. indifference point, 0s delay4.34.711.72.9-2.90.92.0-2.0-3.1-3.13.2-3.2-0.7-0.51.2-0.20.20.4-0.33.40.23.33.2-1.6-1.61.6
Delay disc. indifference point, 16s delay0.10.10.20.4-0.40.10.3-0.3-0.4-0.40.4-0.4-0.1-0.10.2-0.00.10.1-0.00.40.00.40.4-0.2-0.20.2
Delay disc. indifference point, 2s delay3.23.68.02.6-2.61.32.0-2.0-2.7-2.72.8-2.8-1.1-0.91.5-0.70.70.90.32.7-0.42.62.4-0.8-0.80.8
Delay disc. indifference point, 24s delay0.20.20.50.7-0.70.50.6-0.6-0.7-0.70.6-0.6-0.5-0.40.4-0.30.60.40.00.5-0.20.50.5-0.1-0.10.1
Delay disc. indifference point, 4s delay0.90.92.51.1-1.1-0.00.5-0.5-1.2-1.21.3-1.30.10.20.10.4-0.3-0.2-0.61.50.51.61.6-1.1-1.11.1
Delay disc. indifference point, 8s delay0.91.01.51.0-1.01.21.2-1.2-0.9-0.91.0-1.0-1.1-1.21.2-1.11.01.11.20.6-1.10.30.10.70.7-0.7
Indifference point function ln k0.20.30.40.6-0.60.60.6-0.6-0.6-0.60.5-0.5-0.6-0.60.6-0.60.50.50.50.5-0.50.30.20.30.3-0.3
Indifference point function log k0.20.30.40.6-0.60.60.6-0.6-0.6-0.60.5-0.5-0.6-0.60.6-0.60.50.50.50.5-0.50.30.20.30.3-0.3
Patch foraging total patch changes 0 sec0.10.10.20.5-0.50.40.4-0.4-0.5-0.40.5-0.5-0.3-0.40.3-0.30.30.30.30.5-0.20.40.30.10.1-0.1
Patch foraging total patch changes 12 sec0.50.61.20.6-0.61.00.8-0.8-0.4-0.30.5-0.5-1.1-1.00.9-1.01.11.01.1-0.0-1.0-0.2-0.30.90.9-0.9
Patch foraging total patch changes 18 sec0.60.81.5-1.21.2-0.8-1.11.11.11.1-1.21.20.80.7-0.90.6-0.7-0.7-0.5-1.00.6-0.9-0.7-0.1-0.10.1
Patch foraging total patch changes 24 sec0.10.10.2-0.40.4-0.5-0.40.40.40.3-0.30.30.40.5-0.40.5-0.4-0.4-0.4-0.20.4-0.10.0-0.3-0.30.3
Patch foraging total patch changes 6 sec0.10.10.3-0.50.5-0.3-0.30.30.40.5-0.50.50.30.2-0.30.2-0.2-0.2-0.2-0.40.1-0.3-0.30.10.1-0.1
Patch foraging time to switch 0 sec1.01.54.01.6-1.60.50.9-0.9-1.7-1.81.9-1.9-0.3-0.20.50.00.10.1-0.22.00.22.01.9-1.0-1.01.0
Patch foraging water rate 0 sec0.61.02.1-0.20.20.80.5-0.50.50.7-0.70.7-1.0-1.10.9-1.11.11.11.1-1.0-1.3-1.2-1.41.51.5-1.5
Patch foraging water rate 12 sec1.62.44.11.2-1.22.01.8-1.8-0.9-0.90.7-0.7-2.0-2.01.9-2.02.02.01.90.1-2.0-0.3-0.61.61.6-1.6
Patch foraging water rate 18 sec2.23.06.5-0.40.41.50.8-0.80.81.0-1.01.0-1.7-1.81.4-2.02.01.92.1-1.8-2.1-2.1-2.32.52.5-2.5
Patch foraging water rate 24 sec3.65.09.80.5-0.52.51.8-1.80.10.2-0.20.2-2.6-2.82.4-2.92.92.83.0-1.2-3.0-1.8-2.23.13.1-3.1
Patch foraging water rate 6 sec1.11.64.1-0.80.80.70.0-0.01.21.1-1.21.2-0.8-1.00.5-1.11.11.01.3-1.7-1.3-1.9-2.01.81.8-1.8
Seeking ratio, delayed vs. immediate footshock3.84.47.3-2.52.5-2.4-2.72.72.32.3-2.22.22.32.2-2.52.1-2.1-2.2-1.9-1.72.0-1.3-0.9-0.9-0.90.9
Distance traveled before self-admin0.10.20.40.5-0.5-0.00.3-0.3-0.6-0.40.6-0.6-0.00.10.10.1-0.1-0.0-0.20.60.10.70.7-0.4-0.40.4
Distance traveled after self-admin0.70.81.3-1.11.1-1.1-1.11.11.01.2-0.90.91.01.0-1.10.9-0.8-1.0-0.9-0.70.8-0.6-0.4-0.4-0.40.4
Extensor digitorum longus weight3.313.219.74.3-4.34.44.1-4.1-4.0-3.93.9-3.9-4.3-4.24.1-4.04.03.83.72.7-3.51.91.22.12.1-2.1
Bone: elastic displacement0.20.20.3-0.60.6-0.5-0.40.40.60.5-0.50.50.50.5-0.40.5-0.5-0.4-0.4-0.40.3-0.3-0.2-0.2-0.20.2
Bone: elastic work0.20.20.60.5-0.5-0.10.3-0.3-0.6-0.60.6-0.60.10.20.10.2-0.3-0.1-0.30.80.20.80.8-0.6-0.60.6
Bone: endosteal estimation0.20.41.20.7-0.7-0.10.2-0.2-0.9-0.90.8-0.80.20.2-0.00.3-0.3-0.3-0.41.10.41.11.1-0.8-0.80.8
Bone: endosteal perimeter0.71.42.6-0.60.6-1.4-1.31.30.30.3-0.40.41.51.5-1.51.5-1.6-1.6-1.60.21.60.50.7-1.4-1.41.4
Epididymis fat weight0.10.31.0-0.60.60.0-0.30.30.80.8-0.70.7-0.2-0.2-0.1-0.30.30.20.3-1.0-0.3-1.0-1.00.70.7-0.7
Delta time in closed arm before/after self-admin2.82.75.10.6-0.61.91.4-1.4-0.2-0.20.3-0.3-2.0-2.01.8-2.12.22.12.3-0.7-2.2-1.1-1.32.22.2-2.2
Delta time in open arm before/after self-admin0.80.81.61.2-1.20.71.0-1.0-1.3-1.21.2-1.2-0.6-0.60.8-0.50.50.60.31.2-0.41.10.9-0.2-0.20.2
Diff in mean of infusions in LGA sessions0.91.01.9-1.41.4-0.9-1.21.21.31.3-1.41.40.90.8-1.00.7-0.7-0.8-0.6-1.20.6-1.0-0.9-0.0-0.00.0
Delay discount exponential model param1.01.12.3-1.41.4-0.8-1.21.21.51.5-1.51.50.70.6-0.90.5-0.5-0.6-0.3-1.50.3-1.4-1.20.40.4-0.4
Extinction: sum of active levers before priming1.01.02.8-1.11.1-0.0-0.60.61.31.4-1.41.4-0.1-0.2-0.2-0.40.30.20.4-1.6-0.5-1.7-1.71.11.1-1.1
Active lever presses in extinction session 62.12.03.3-1.81.8-1.6-1.81.81.71.7-1.81.81.51.4-1.61.3-1.3-1.4-1.1-1.41.2-1.1-0.9-0.5-0.50.5
Bone: final force0.81.43.81.4-1.40.10.4-0.4-1.7-1.71.6-1.6-0.00.1-0.00.3-0.3-0.3-0.51.90.62.01.9-1.2-1.21.2
Bone: final moment0.71.23.31.3-1.30.00.3-0.3-1.5-1.51.4-1.40.10.2-0.10.3-0.3-0.4-0.51.80.61.81.8-1.1-1.11.1
Food consumed during 24 hour testing period0.30.40.60.8-0.80.70.8-0.8-0.8-0.80.7-0.7-0.6-0.60.7-0.50.60.60.50.6-0.50.50.40.20.2-0.2
Glucose0.81.22.11.3-1.31.21.4-1.4-1.2-1.21.3-1.3-1.1-1.11.3-1.01.11.10.91.0-1.00.70.60.40.4-0.4
Heart weight0.30.41.2-0.80.8-0.1-0.30.30.90.9-0.80.8-0.0-0.1-0.1-0.20.10.20.5-1.1-0.3-1.1-1.10.70.7-0.7
Delay discount hyperbolic model param1.51.63.4-1.71.7-0.9-1.41.41.81.8-1.91.90.80.7-1.10.6-0.6-0.7-0.4-1.80.4-1.6-1.50.40.4-0.4
Intermittent access intake day 1-15 change3.83.88.0-2.72.7-1.6-2.22.22.82.8-2.82.81.51.3-1.71.1-1.1-1.3-0.9-2.50.8-2.3-2.10.30.3-0.3
Intermittent access intake escalation3.83.88.9-2.62.6-0.8-1.71.72.92.9-2.92.90.70.4-1.00.2-0.3-0.40.0-3.0-0.1-2.9-2.91.31.3-1.3
Intermittent access intake escalation 24.64.610.4-2.92.9-1.2-2.12.13.23.2-3.23.21.00.7-1.40.5-0.6-0.7-0.1-3.20.2-3.1-2.91.11.1-1.1
Intermitt. access day 1 inactive lever presses0.50.51.5-0.70.70.1-0.30.30.90.9-0.90.9-0.2-0.30.0-0.40.40.30.5-1.1-0.5-1.2-1.20.90.9-0.9
Intermitt. access day 15 inactive lever presses0.30.30.9-0.60.60.1-0.20.20.70.7-0.80.8-0.0-0.2-0.0-0.20.20.10.3-0.8-0.3-0.9-0.90.60.6-0.6
Intermitt. access escalation Index1.00.92.10.4-0.5-0.7-0.20.2-0.8-0.80.7-0.70.70.9-0.61.0-1.0-0.9-1.01.11.11.31.5-1.4-1.41.4
Intermittent access day 1 total infusions0.10.10.20.4-0.40.20.3-0.3-0.4-0.40.3-0.3-0.1-0.10.2-0.10.00.10.00.4-0.10.40.4-0.1-0.10.1
Intermittent access day 15 total infusions1.01.12.8-1.41.4-0.4-0.90.91.51.5-1.71.70.40.2-0.50.1-0.2-0.2-0.0-1.6-0.0-1.6-1.50.70.7-0.7
Intermittent access terminal intake (last 3 days)0.60.71.5-1.11.1-0.8-1.01.01.01.0-1.21.20.70.7-0.80.6-0.7-0.7-0.5-1.00.5-0.8-0.7-0.1-0.10.1
Intermittent access total infusions0.10.10.3-0.30.40.1-0.10.10.40.4-0.60.6-0.1-0.20.0-0.20.10.10.2-0.5-0.2-0.5-0.60.40.4-0.4
Intermittent access day 1 locomotion0.10.20.4-0.50.50.0-0.20.20.50.5-0.60.60.0-0.1-0.0-0.10.00.00.1-0.6-0.2-0.6-0.60.40.4-0.4
Intermittent access day 15 total locomotion1.81.94.6-1.91.9-1.0-1.51.52.02.0-2.22.20.90.7-1.10.6-0.7-0.8-0.5-1.90.4-1.8-1.70.50.5-0.5
Intermittent access total locomotion0.50.61.4-1.11.1-0.6-0.90.91.01.0-1.21.20.70.5-0.70.5-0.6-0.6-0.5-0.90.4-0.9-0.80.10.1-0.1
Intermittent access standard deviation1.81.94.3-1.91.9-1.0-1.51.52.02.0-2.12.10.90.8-1.10.6-0.6-0.7-0.4-1.90.4-1.8-1.70.40.4-0.4
Left kidney weight0.30.91.7-0.30.3-1.1-0.80.80.00.0-0.10.11.11.2-1.11.3-1.2-1.2-1.10.41.30.70.9-1.3-1.31.3
Right kidney weight1.13.15.3-2.12.1-2.0-2.32.32.01.9-1.91.91.91.9-2.21.8-1.8-1.9-1.4-1.51.6-1.1-0.8-0.8-0.80.8
Cocaine induced anxiety1.51.72.9-1.01.0-1.7-1.51.50.70.7-0.60.61.61.7-1.61.7-1.6-1.7-1.5-0.11.70.20.5-1.4-1.41.4
Post-drug Anxiety2.02.24.1-0.70.7-1.9-1.51.50.40.4-0.30.31.82.0-1.82.0-1.8-1.9-1.90.32.00.81.1-1.9-1.91.9
Baseline Anxiety0.10.10.3-0.10.10.40.2-0.20.20.2-0.30.3-0.4-0.40.3-0.50.40.40.3-0.4-0.5-0.5-0.50.60.6-0.6
Tail length1.75.210.8-3.23.2-1.9-2.52.53.33.3-3.33.31.71.5-2.01.2-1.3-1.4-0.9-3.10.9-2.8-2.60.50.5-0.5
Length with tail1.14.07.3-2.72.7-2.1-2.32.32.62.6-2.62.62.11.9-2.01.7-1.8-1.8-1.5-2.01.4-1.7-1.4-0.4-0.40.4
Length without tail0.30.61.2-0.20.3-0.9-0.60.60.00.0-0.10.11.01.0-0.81.0-1.1-1.0-1.00.51.00.70.7-1.0-1.01.0
Times rat made contact with spout0.40.51.00.4-0.40.90.4-0.4-0.2-0.20.3-0.3-0.9-0.90.6-0.91.00.81.0-0.1-0.8-0.3-0.40.90.9-0.9
Lifetime Intake0.00.00.1-0.20.2-0.1-0.10.10.10.1-0.30.30.10.1-0.10.0-0.1-0.1-0.1-0.10.0-0.1-0.10.00.0-0.0
Liver weight, left1.72.84.22.0-2.02.01.9-1.9-1.9-1.91.9-1.9-2.0-1.81.8-1.81.81.71.61.3-1.51.00.70.80.8-0.8
Liver weight, right1.01.73.11.8-1.81.21.5-1.5-1.7-1.71.8-1.8-1.2-1.11.3-1.00.91.00.81.5-0.81.31.10.10.1-0.1
Locomotor activity3.04.78.1-2.32.3-2.6-2.82.82.01.9-2.02.02.62.5-2.82.4-2.4-2.6-2.3-1.22.3-0.7-0.4-1.4-1.41.4
Locomotor testing distance1.52.53.7-1.81.8-1.9-1.91.91.61.6-1.71.71.91.8-1.91.7-1.8-1.8-1.6-1.01.6-0.7-0.4-0.9-0.90.9
Locomotor testing rearing0.00.10.1-0.10.10.10.1-0.10.20.2-0.30.3-0.2-0.20.2-0.20.20.20.2-0.3-0.3-0.3-0.40.30.3-0.3
Locomotion in novel chamber0.30.40.9-0.80.8-0.5-0.70.70.90.9-0.90.90.30.3-0.60.3-0.1-0.3-0.3-1.00.3-0.9-0.80.10.1-0.1
Locomotion in novel chamber post-restriction0.50.61.0-0.90.9-0.8-1.01.01.00.9-1.01.00.70.7-0.90.7-0.6-0.8-0.7-0.70.7-0.6-0.5-0.3-0.30.3
Fecal boli incidents, locomotor time 12.02.23.71.5-1.41.71.9-1.9-1.3-1.01.2-1.2-1.8-1.81.9-1.81.61.81.80.6-1.80.30.01.21.2-1.2
Change in fecal boli incidents, locomotor task1.41.32.4-0.50.5-1.3-1.11.10.30.1-0.30.31.41.4-1.31.5-1.5-1.5-1.50.31.50.60.8-1.5-1.51.5
Time >=10cm from walls, locomotor time 10.50.51.40.6-0.6-0.30.3-0.3-0.7-0.70.7-0.70.30.4-0.10.5-0.5-0.4-0.71.10.61.21.2-1.0-1.01.0
Bouts of movement, locomotor time 10.10.10.3-0.40.4-0.2-0.20.20.40.5-0.50.50.10.1-0.10.1-0.1-0.1-0.1-0.4-0.0-0.4-0.40.20.2-0.2
Total resting periods, locomotor time 10.10.10.3-0.50.5-0.4-0.40.40.40.6-0.50.50.40.3-0.30.3-0.4-0.3-0.3-0.40.2-0.3-0.2-0.1-0.10.1
Rest time, locomotor task time 10.20.20.6-0.40.4-0.6-0.40.40.30.3-0.40.40.60.6-0.50.6-0.5-0.5-0.7-0.10.50.00.1-0.5-0.50.5
Distance moved, locomotor task time 10.50.61.50.6-0.6-0.20.0-0.0-0.8-0.90.8-0.80.40.4-0.30.5-0.5-0.5-0.61.10.71.21.2-1.0-1.01.0
Vertical activity count, locomotor time 10.10.10.20.2-0.20.40.2-0.2-0.1-0.00.2-0.2-0.4-0.40.3-0.40.50.40.5-0.1-0.4-0.1-0.20.40.4-0.4
Time >=10cm from walls, locomotor time 21.01.01.81.1-1.11.31.2-1.2-1.0-1.10.9-0.9-1.2-1.21.2-1.21.21.21.00.6-1.10.30.20.70.7-0.7
Bouts of movement, locomotor time 20.90.91.7-0.60.6-1.2-0.90.90.40.4-0.40.41.21.3-1.11.3-1.3-1.2-1.30.11.20.40.5-1.2-1.21.2
Total resting periods, locomotor time 21.01.12.0-0.60.5-1.3-0.90.90.40.4-0.30.31.31.4-1.21.4-1.4-1.3-1.40.21.40.50.7-1.3-1.31.3
Rest time, locomotor task time 20.70.81.5-0.70.7-1.2-1.01.00.50.6-0.60.61.11.2-1.11.2-1.2-1.1-1.2-0.11.10.10.3-1.0-1.01.0
Distance moved, locomotor task time 20.91.12.01.0-0.91.41.2-1.2-0.8-0.90.8-0.8-1.3-1.31.3-1.31.31.31.20.3-1.20.1-0.11.01.0-1.0
Vertical activity count, locomotor time 21.61.73.00.9-0.91.71.4-1.4-0.7-0.70.6-0.6-1.6-1.71.6-1.71.71.71.60.0-1.7-0.3-0.61.51.5-1.5
Light reinforcement 13.56.411.2-3.33.4-2.7-3.13.13.23.2-3.23.22.62.4-2.72.2-2.2-2.3-1.9-2.61.9-2.1-1.8-0.5-0.50.5
Light reinforcement 21.01.42.4-1.51.5-1.2-1.51.51.41.5-1.51.51.21.1-1.31.0-1.0-1.1-0.9-1.20.9-1.0-0.8-0.2-0.20.2
Bone: marrow area0.20.41.20.7-0.7-0.10.2-0.2-0.9-0.90.8-0.80.10.2-0.00.3-0.3-0.2-0.41.10.41.11.1-0.7-0.70.7
Bone: maximum diameter1.42.54.6-1.01.0-1.9-1.91.90.60.6-0.80.81.91.9-2.12.0-2.0-2.1-2.00.12.10.50.8-1.8-1.81.8
Bone: maximum force0.81.33.61.5-1.50.40.6-0.6-1.8-1.81.6-1.6-0.3-0.10.20.00.0-0.1-0.21.90.31.91.8-0.9-0.90.9
Bone: maximum moment0.71.13.21.4-1.40.30.6-0.6-1.7-1.61.5-1.5-0.2-0.10.20.1-0.1-0.1-0.21.80.31.81.7-0.9-0.90.9
Mean time between licks in bursts2.13.06.5-2.42.4-1.4-1.81.82.52.5-2.62.61.21.1-1.40.9-0.9-1.0-0.6-2.40.6-2.2-2.00.50.5-0.5
Mean num. licks in bursts0.10.10.30.0-0.0-0.40.2-0.2-0.1-0.10.3-0.30.40.4-0.00.5-0.4-0.2-0.40.30.30.40.4-0.5-0.50.5
Cd content in liver0.10.10.20.4-0.40.20.1-0.1-0.5-0.50.5-0.5-0.2-0.20.1-0.10.10.00.10.50.00.50.4-0.1-0.10.1
Co content in liver0.40.51.1-0.90.9-0.2-0.90.90.90.9-0.90.90.20.1-0.60.0-0.0-0.30.1-1.00.1-1.0-1.00.50.5-0.5
Cu content in liver0.50.61.30.3-0.3-0.6-0.30.3-0.5-0.50.5-0.50.70.8-0.60.8-0.8-0.8-0.90.90.91.01.1-1.2-1.21.2
Fe content in liver0.20.20.5-0.10.10.40.1-0.10.20.2-0.20.2-0.4-0.50.3-0.50.50.40.6-0.5-0.5-0.6-0.60.70.7-0.7
K content in liver0.60.61.3-0.00.0-0.8-0.30.3-0.2-0.20.2-0.20.91.0-0.51.0-1.0-0.8-1.00.60.90.80.9-1.1-1.11.1
Mg content in liver0.90.92.1-0.00.0-1.0-0.50.5-0.2-0.20.2-0.21.11.2-0.91.3-1.2-1.1-1.30.81.21.01.2-1.4-1.41.4
Mn content in liver3.54.07.7-1.01.0-2.5-1.61.60.50.5-0.50.52.62.7-2.12.7-2.7-2.4-2.80.62.61.11.5-2.6-2.62.6
Na content in liver0.70.71.81.1-1.10.30.8-0.8-1.2-1.21.2-1.2-0.2-0.10.50.00.00.1-0.11.30.11.31.3-0.6-0.60.6
Rb content in liver0.81.02.60.7-0.7-0.50.1-0.1-0.9-0.90.9-0.90.60.7-0.40.9-0.8-0.7-1.01.40.91.51.6-1.4-1.41.4
Se content in liver0.10.20.3-0.50.5-0.5-0.40.40.40.4-0.40.40.60.6-0.40.5-0.5-0.4-0.5-0.30.4-0.2-0.1-0.3-0.30.3
Sr content in liver0.80.81.8-0.10.10.90.4-0.40.30.3-0.30.3-0.9-1.00.7-1.11.11.01.2-0.8-1.1-1.0-1.11.31.3-1.3
Zn content in liver1.92.16.0-1.61.60.1-0.70.71.91.9-1.91.9-0.3-0.4-0.1-0.60.60.40.9-2.4-0.8-2.4-2.41.71.7-1.7
Bone: minimum diameter0.30.61.30.2-0.2-0.7-0.50.5-0.4-0.40.3-0.30.80.8-0.70.9-0.9-0.9-1.00.81.00.91.0-1.1-1.11.1
Time in familiar zone, hab. session 11.21.12.5-1.51.5-0.8-1.11.11.61.6-1.51.50.70.6-0.80.5-0.5-0.6-0.3-1.50.3-1.4-1.30.30.3-0.3
Time in novel zone, hab. session 10.90.92.61.0-1.0-0.10.1-0.1-1.2-1.21.1-1.10.20.3-0.20.4-0.4-0.5-0.61.50.71.61.6-1.2-1.21.2
Total zone transitions, hab. session 11.41.93.6-1.11.1-1.8-1.21.20.80.8-0.80.81.91.9-1.51.9-1.8-1.6-1.9-0.11.70.30.6-1.6-1.61.6
Total locomotion distance, hab. session 12.84.07.3-1.21.2-2.5-1.71.70.80.8-0.60.62.62.7-2.22.7-2.6-2.5-2.70.32.60.91.2-2.5-2.52.5
Locomotion velocity, hab. session 12.43.46.1-1.41.4-2.4-1.81.81.11.1-1.01.02.42.5-2.12.5-2.4-2.2-2.4-0.22.30.30.7-2.1-2.12.1
Time in familiar zone, hab. session 23.63.78.0-2.72.7-1.3-2.12.12.82.8-2.72.71.11.0-1.60.7-0.7-1.0-0.4-2.80.5-2.6-2.40.80.8-0.8
Time in novel zone, hab. session 22.72.76.52.2-2.20.91.6-1.6-2.4-2.42.4-2.4-0.7-0.51.1-0.30.30.50.02.5-0.12.52.3-1.0-1.01.0
Total zone transitions, hab. session 21.01.33.30.4-0.4-0.90.5-0.5-0.7-0.70.8-0.81.01.2-0.11.3-1.2-0.6-1.41.41.01.61.8-1.8-1.81.8
Total locomotion distance, hab. session 21.11.53.1-1.11.1-1.7-0.70.70.90.9-0.70.71.71.8-1.01.8-1.7-1.3-1.7-0.21.30.20.4-1.4-1.41.4
Locomotion velocity, hab. session 21.52.04.1-1.01.0-1.9-0.80.80.70.7-0.60.61.92.0-1.22.0-1.9-1.5-2.00.11.60.50.8-1.8-1.81.8
Novel to familiar place preference ratio2.52.66.42.1-2.10.51.5-1.5-2.3-2.32.3-2.3-0.4-0.20.90.0-0.00.3-0.32.50.12.52.4-1.3-1.31.3
Novelty place preference1.61.74.31.5-1.60.21.1-1.1-1.8-1.81.8-1.8-0.10.10.60.2-0.20.1-0.52.10.32.12.1-1.3-1.31.3
Time in novel zone, NPP test1.71.84.41.7-1.70.41.2-1.2-1.9-1.91.9-1.9-0.3-0.10.70.1-0.10.2-0.32.10.22.12.0-1.2-1.21.2
Total zone transitions, NPP test0.20.30.90.1-0.1-0.60.4-0.4-0.2-0.20.3-0.30.60.70.10.7-0.7-0.2-0.80.60.40.70.8-0.9-0.90.9
Total locomotion distance, NPP test0.50.71.90.1-0.1-0.80.1-0.1-0.3-0.30.5-0.50.91.0-0.31.1-1.0-0.7-1.10.80.91.11.2-1.4-1.41.4
Locomotion velocity, NPP test0.50.71.8-0.20.2-1.0-0.10.1-0.0-0.00.2-0.21.11.2-0.41.2-1.1-0.8-1.20.60.90.81.0-1.3-1.31.3
Intraocular pressure0.70.92.1-0.20.20.80.4-0.40.50.6-0.50.5-1.0-1.00.7-1.11.21.01.1-1.1-1.2-1.3-1.31.41.4-1.4
Delta distance traveled before/after self-admin1.01.11.9-1.41.4-1.1-1.31.31.31.3-1.31.31.00.9-1.10.9-0.9-1.0-0.8-1.10.8-0.9-0.8-0.2-0.20.2
Delta ambulatory time before/after self-admin1.41.52.4-1.41.4-1.5-1.51.51.31.3-1.31.31.41.4-1.51.3-1.3-1.4-1.2-0.91.2-0.6-0.4-0.7-0.70.7
Parametrial fat weight0.30.51.1-1.01.0-0.4-0.90.91.01.0-1.01.00.40.2-0.60.1-0.2-0.4-0.1-1.00.1-1.0-1.00.40.4-0.4
Pavlov. Cond. lever latency0.60.81.8-0.10.10.90.4-0.40.30.3-0.40.4-0.9-1.00.7-1.11.11.01.1-0.8-1.1-1.0-1.11.31.3-1.3
Pavlov. Cond. magazine entry latency1.41.93.9-1.91.9-1.3-1.41.41.91.9-2.02.01.21.0-1.20.9-0.9-0.9-0.7-1.70.6-1.5-1.40.10.1-0.1
Pavlov. Cond. change in total contacts0.00.00.1-0.30.3-0.3-0.00.00.30.3-0.20.20.30.3-0.10.3-0.2-0.1-0.3-0.20.1-0.1-0.0-0.2-0.20.2
Pavlov. Cond. index score0.50.71.2-0.70.7-1.1-0.70.70.50.5-0.50.51.11.1-0.91.1-1.1-1.0-1.1-0.11.00.10.3-0.9-0.90.9
Pavlov. Cond. latency score0.81.12.0-0.60.6-1.3-0.80.80.40.4-0.40.41.31.4-1.11.4-1.4-1.2-1.40.21.30.40.6-1.3-1.31.3
Pavlov. Cond. lever contacts1.11.22.6-0.20.2-1.2-0.80.8-0.1-0.10.2-0.21.31.4-1.11.4-1.4-1.3-1.50.71.51.01.2-1.6-1.61.6
Pavlov. Cond. magazine entry number0.30.40.80.9-0.90.70.6-0.6-0.8-0.80.9-0.9-0.7-0.60.6-0.60.60.50.50.7-0.40.60.50.10.1-0.1
Pavlov. Cond. intertrial magazine entries0.30.40.9-0.30.30.5-0.00.00.50.5-0.60.6-0.5-0.60.3-0.60.70.50.7-0.8-0.6-0.9-1.01.01.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.70.91.6-0.90.9-1.2-0.90.90.80.8-0.80.81.21.2-1.01.2-1.2-1.1-1.2-0.31.1-0.10.1-0.9-0.90.9
Pavlov. Cond. response bias0.60.81.3-1.11.1-1.0-1.01.01.11.1-1.11.10.90.9-0.90.8-0.8-0.8-0.7-0.90.7-0.7-0.6-0.3-0.30.3
Pavlov. Cond. lever latency0.70.91.71.2-1.21.01.3-1.3-1.1-1.11.0-1.0-1.0-1.01.2-0.90.91.00.80.9-0.90.70.50.30.3-0.3
Pavlov. Cond. magazine entry latency0.60.61.3-0.80.8-0.9-1.21.20.60.6-0.70.70.90.9-1.10.9-0.9-1.0-0.9-0.40.9-0.2-0.1-0.6-0.60.6
Pavlov. Cond. change in total contacts0.60.81.6-1.21.2-0.8-1.31.31.21.2-1.11.10.80.7-1.00.6-0.6-0.8-0.5-1.10.6-0.9-0.80.00.0-0.0
Pavlov. Cond. index score0.70.91.9-1.21.2-1.0-1.41.41.11.1-1.11.10.90.9-1.20.8-0.8-1.0-0.7-0.90.8-0.8-0.6-0.2-0.20.2
Pavlov. Cond. latency score0.81.02.1-1.11.1-1.1-1.41.41.01.0-1.01.01.11.0-1.31.0-1.0-1.2-0.9-0.71.0-0.5-0.4-0.5-0.50.5
Pavlov. Cond. lever contacts0.50.71.4-1.11.1-0.7-1.01.01.21.2-1.11.10.60.6-0.80.5-0.5-0.6-0.3-1.10.4-1.0-0.90.10.1-0.1
Pavlov. Cond. magazine entry number0.81.01.91.1-1.11.21.4-1.4-0.9-0.91.0-1.0-1.2-1.21.3-1.11.11.21.00.6-1.10.40.20.60.6-0.6
Pavlov. Cond. intertrial magazine entries0.81.02.10.8-0.81.21.4-1.4-0.6-0.60.4-0.4-1.2-1.21.4-1.21.21.41.10.2-1.3-0.1-0.20.90.9-0.9
Pavlov. Cond. lever-magazine prob. diff.0.81.02.0-1.21.2-1.1-1.41.41.11.1-1.11.11.11.0-1.30.9-1.0-1.1-0.9-0.81.0-0.6-0.5-0.4-0.40.4
Pavlov. Cond. response bias1.21.63.0-1.71.7-1.1-1.61.61.71.7-1.71.71.00.9-1.30.8-0.8-1.0-0.6-1.60.7-1.4-1.30.10.1-0.1
Time in closed arm before self-admin0.80.92.31.0-1.0-0.00.5-0.5-1.2-1.31.2-1.20.10.20.10.3-0.3-0.3-0.61.50.51.51.5-1.1-1.11.1
Time in closed arm after self-admin0.00.00.1-0.20.2-0.1-0.10.10.30.3-0.00.00.00.1-0.10.00.10.00.1-0.3-0.0-0.2-0.20.10.1-0.1
Time in open arm before self-admin0.70.71.6-1.21.2-0.6-1.01.01.31.2-1.21.20.60.5-0.70.4-0.3-0.4-0.2-1.20.2-1.1-1.00.30.3-0.3
Time in open arm after self-admin0.60.71.21.0-1.01.11.0-1.0-0.9-0.90.8-0.8-0.9-1.01.0-0.90.90.90.80.6-0.90.40.20.50.5-0.5
Bone: periosteal estimation0.71.33.70.9-0.9-0.5-0.20.2-1.3-1.31.1-1.10.60.7-0.60.9-0.9-0.9-1.11.71.11.81.9-1.6-1.61.6
Bone: periosteal perimeter0.91.63.0-0.20.2-1.3-1.21.2-0.2-0.20.0-0.01.41.4-1.51.5-1.6-1.6-1.60.81.71.11.3-1.7-1.71.7
Bone: post-yield work0.40.51.11.0-1.00.80.7-0.7-1.1-1.00.8-0.8-0.7-0.70.7-0.60.60.60.50.8-0.50.70.60.10.1-0.1
Progressive ratio test 1 active lever presses0.30.30.60.4-0.40.70.7-0.7-0.3-0.30.2-0.2-0.7-0.70.7-0.70.60.70.80.1-0.7-0.1-0.20.50.5-0.5
Progressive ratio test 1 breakpoint0.30.30.40.5-0.50.70.7-0.7-0.5-0.50.3-0.3-0.6-0.60.7-0.60.50.60.70.2-0.60.10.00.40.4-0.4
Progressive ratio test 1 inactive lever presses0.00.00.0-0.00.00.0-0.00.00.00.0-0.10.10.0-0.0-0.0-0.0-0.0-0.0-0.00.0-0.0-0.0-0.00.00.0-0.0
Progressive ratio test 2 active lever presses0.20.20.5-0.50.50.0-0.20.20.60.6-0.70.7-0.1-0.1-0.0-0.20.10.10.1-0.7-0.2-0.7-0.70.50.5-0.5
Progressive ratio test 2 breakpoint0.20.20.5-0.60.6-0.5-0.60.60.60.6-0.70.70.40.4-0.50.4-0.4-0.4-0.4-0.50.3-0.4-0.3-0.1-0.10.1
Progressive ratio test 2 inactive lever presses0.00.00.1-0.20.2-0.3-0.20.20.10.1-0.20.20.30.3-0.30.2-0.3-0.3-0.3-0.10.2-0.00.0-0.2-0.20.2
Incentive Sensitization - Responses0.30.30.7-0.60.6-0.2-0.40.40.70.7-0.80.80.10.1-0.20.00.1-0.0-0.1-0.9-0.0-0.8-0.80.40.4-0.4
Incentive Sensitization - Breakpoint0.30.30.7-0.70.7-0.4-0.60.60.80.8-0.80.80.30.3-0.40.2-0.2-0.2-0.3-0.80.2-0.7-0.60.10.1-0.1
Sum of active levers in priming session hrs 5-60.00.00.10.0-0.00.20.1-0.1-0.00.0-0.10.1-0.2-0.20.2-0.20.20.20.2-0.1-0.2-0.1-0.20.20.2-0.2
Progressive ratio0.20.30.50.4-0.40.60.5-0.5-0.3-0.30.4-0.4-0.7-0.60.6-0.60.70.70.7-0.1-0.7-0.2-0.20.60.6-0.6
Food seeking constrained by brief footshock0.10.10.2-0.40.4-0.3-0.50.50.50.3-0.30.30.30.3-0.40.3-0.2-0.3-0.1-0.40.3-0.3-0.2-0.0-0.00.0
Seeking ratio, punishment vs. effort0.10.10.2-0.30.3-0.4-0.40.40.30.2-0.30.30.40.4-0.40.4-0.4-0.5-0.4-0.00.40.00.0-0.3-0.30.3
Retroperitoneal fat weight0.61.83.31.3-1.31.71.8-1.8-1.2-1.11.0-1.0-1.5-1.71.8-1.61.41.61.50.7-1.60.30.11.01.0-1.0
Reaction time number correct1.01.52.60.8-0.81.51.4-1.4-0.5-0.60.5-0.5-1.6-1.61.5-1.61.61.61.5-0.0-1.6-0.4-0.61.31.3-1.3
Reaction time mean minus median0.60.81.3-1.11.0-1.2-1.01.00.91.1-1.11.11.01.0-1.00.9-1.0-0.9-0.8-0.70.8-0.5-0.3-0.5-0.50.5
Reaction time mean minus median AUC1.01.33.0-0.10.1-1.4-0.50.5-0.4-0.20.1-0.11.31.4-0.91.5-1.5-1.2-1.60.91.41.21.4-1.7-1.71.7
Reaction time num false alarms0.10.10.30.2-0.20.40.4-0.4-0.0-0.10.0-0.0-0.5-0.40.5-0.40.50.50.5-0.1-0.5-0.2-0.30.40.4-0.4
Reaction time num false alarms AUC0.30.40.80.3-0.30.80.7-0.7-0.1-0.20.1-0.1-0.8-0.80.8-0.80.80.90.9-0.3-0.9-0.4-0.50.80.8-0.8
Reaction time trials correct on left1.01.52.60.8-0.81.51.4-1.4-0.5-0.60.5-0.5-1.6-1.61.5-1.61.61.61.5-0.0-1.6-0.4-0.61.31.3-1.3
Reaction time trials on left1.01.42.40.9-0.91.51.3-1.3-0.6-0.60.5-0.5-1.5-1.51.5-1.51.51.51.50.0-1.5-0.3-0.51.21.2-1.2
Reaction time mean0.50.81.70.1-0.1-0.9-0.40.4-0.4-0.20.2-0.20.91.0-0.71.1-1.1-0.9-1.10.81.11.01.1-1.3-1.31.3
Reaction time mean AUC0.50.71.60.2-0.2-0.8-0.30.3-0.5-0.30.3-0.30.80.9-0.60.9-1.0-0.9-1.10.91.01.01.1-1.2-1.21.2
Median of all reaction times0.50.72.00.6-0.6-0.40.1-0.1-1.0-0.80.8-0.80.50.6-0.30.7-0.7-0.6-0.81.20.81.41.4-1.2-1.21.2
Reaction time omissions0.20.30.5-0.50.5-0.7-0.50.50.40.4-0.60.60.70.7-0.50.7-0.7-0.6-0.6-0.20.6-0.10.0-0.5-0.50.5
Reaction time false alarm rate0.00.00.00.0-0.1-0.10.1-0.1-0.1-0.10.1-0.10.10.2-0.00.2-0.1-0.1-0.10.10.10.20.2-0.2-0.20.2
Reaction time premature initiation rate0.70.92.4-1.11.1-0.1-0.40.41.41.3-1.31.30.0-0.1-0.0-0.30.20.20.3-1.5-0.5-1.6-1.61.01.0-1.0
Reaction time premature initiations1.11.63.9-0.80.80.70.3-0.31.21.1-1.21.2-0.8-1.00.8-1.11.11.11.2-1.6-1.4-1.9-2.01.81.8-1.8
Std. dev. reaction times0.40.61.3-0.60.5-1.2-0.60.60.20.5-0.60.61.01.1-0.81.1-1.1-0.9-1.1-0.00.90.20.4-1.0-1.01.0
Reaction time trials completed1.01.42.40.9-0.91.51.3-1.3-0.6-0.60.5-0.5-1.5-1.51.5-1.51.51.51.50.0-1.5-0.3-0.51.21.2-1.2
Reaction time trials AUC1.21.73.00.8-0.81.61.4-1.4-0.5-0.50.4-0.4-1.7-1.71.6-1.71.71.71.7-0.2-1.7-0.5-0.71.51.5-1.5
Run reversals in cocaine runway, females1.01.01.8-0.90.9-1.3-1.31.30.80.8-0.50.51.21.3-1.31.3-1.1-1.3-1.0-0.41.2-0.10.1-0.9-0.90.9
Run reversals in cocaine runway, males1.41.42.3-1.21.1-1.4-1.51.51.11.0-1.01.01.41.4-1.51.4-1.3-1.4-1.2-0.61.3-0.3-0.1-0.9-0.90.9
Latency to leave start box in cocaine runway1.92.03.9-1.01.0-1.8-1.51.50.60.8-0.90.91.81.8-1.71.8-1.8-1.8-2.00.01.80.40.6-1.6-1.61.6
Latency to leave start box in cocaine runway, F2.02.24.90.1-0.1-1.5-0.90.9-0.5-0.40.2-0.21.61.7-1.31.8-1.8-1.7-2.01.21.91.61.8-2.2-2.22.2
Latency to leave start box in cocaine runway, M1.71.74.2-1.71.7-0.6-1.11.11.81.9-1.91.90.40.3-0.60.1-0.1-0.20.1-2.1-0.1-2.0-1.91.01.0-1.0
Std. dev. time between licks in bursts1.21.52.5-1.00.9-1.5-1.41.40.70.7-0.80.81.51.5-1.61.5-1.5-1.6-1.5-0.21.50.10.3-1.2-1.21.2
Total sessions with >9 infusions0.50.51.2-0.00.0-0.8-0.50.5-0.2-0.20.1-0.10.80.9-0.70.9-0.9-0.9-0.90.51.00.70.8-1.1-1.11.1
Short access day 1 total inactive lever presses0.00.00.0-0.20.2-0.1-0.10.10.20.2-0.20.20.10.1-0.10.0-0.1-0.10.1-0.20.0-0.2-0.20.00.0-0.0
Short access day 10 total inactive lever presses0.30.30.7-0.20.20.50.2-0.20.40.4-0.40.4-0.4-0.60.4-0.60.50.50.8-0.6-0.7-0.8-0.90.80.8-0.8
Short access day 1 total infusions0.60.71.3-0.20.2-1.0-0.70.7-0.0-0.0-0.10.11.01.1-0.91.1-1.1-1.0-1.00.41.10.60.8-1.1-1.11.1
Short access day 10 total infusions0.00.00.00.0-0.0-0.00.0-0.0-0.1-0.1-0.20.2-0.00.0-0.00.0-0.10.0-0.2-0.00.00.00.0-0.1-0.10.1
Short access total infusions0.20.20.60.0-0.1-0.5-0.30.3-0.2-0.20.0-0.00.50.6-0.50.6-0.6-0.5-0.60.40.70.50.6-0.8-0.80.8
Short access day 1 locomotion0.60.61.1-0.80.9-0.9-0.90.90.70.7-0.90.91.00.9-0.90.9-1.0-0.9-0.8-0.30.8-0.2-0.1-0.5-0.50.5
Short access day 10 total locomotion2.32.55.7-2.22.2-1.1-1.71.72.32.3-2.42.41.10.8-1.30.7-0.7-0.9-0.6-2.20.5-2.1-1.90.50.5-0.5
Short access total locomotion0.60.61.0-0.90.9-0.9-1.01.00.80.8-1.01.00.90.8-0.90.8-0.9-0.8-0.7-0.60.7-0.5-0.4-0.3-0.30.3
One hour access (0.3 mA shock)0.20.30.40.6-0.60.60.7-0.7-0.5-0.50.4-0.4-0.5-0.60.6-0.60.50.60.50.4-0.50.20.10.30.3-0.3
Compulsive drug intake0.50.51.40.9-0.90.40.7-0.7-0.9-0.91.2-1.2-0.4-0.30.5-0.30.40.30.21.0-0.20.90.9-0.2-0.20.2
One hour access (shock baseline)0.20.30.6-0.10.10.50.3-0.30.20.2-0.40.4-0.5-0.60.5-0.60.50.60.6-0.4-0.7-0.6-0.70.70.7-0.7
Social response proportion0.60.61.1-0.80.8-1.0-0.90.90.80.7-0.60.61.01.0-0.91.0-1.0-0.9-0.9-0.40.9-0.2-0.0-0.6-0.60.6
Social responses5.87.411.0-3.23.2-3.3-3.33.33.02.8-2.82.83.23.2-3.23.0-3.0-2.9-2.7-2.12.6-1.4-0.9-1.5-1.51.5
Social time0.70.92.01.0-1.01.11.4-1.4-0.9-1.00.9-0.9-1.0-1.01.3-1.00.91.20.90.6-1.00.40.30.50.5-0.5
Soleus weight5.415.728.45.3-5.34.24.5-4.5-5.2-5.25.2-5.2-3.9-3.74.0-3.33.33.32.94.3-2.73.63.00.80.8-0.8
Bone: stiffness1.62.56.02.3-2.31.21.1-1.1-2.5-2.42.3-2.3-1.0-0.90.8-0.70.70.50.52.4-0.22.22.0-0.5-0.50.5
Tibialis anterior weight0.51.73.61.8-1.81.41.0-1.0-1.8-1.81.9-1.9-1.3-1.20.9-1.11.10.81.01.5-0.71.31.10.20.2-0.2
Time to tail flick, vehicle, before self-admin1.71.83.1-0.80.8-1.7-1.31.30.50.5-0.50.51.61.8-1.61.8-1.7-1.7-1.70.11.80.50.7-1.7-1.71.7
Time to tail flick, vehicle, after self-admin0.40.41.0-0.30.30.40.1-0.10.60.6-0.40.4-0.5-0.50.3-0.60.70.60.7-0.9-0.7-1.0-1.00.90.9-0.9
Time to tail flick, test, before self-admin1.31.32.6-0.30.3-1.3-0.90.90.1-0.0-0.10.11.31.5-1.21.5-1.5-1.4-1.50.51.50.81.0-1.6-1.61.6
Time to tail flick, test, after self-admin0.60.61.2-0.40.4-1.0-0.70.70.20.1-0.30.30.91.0-0.91.0-1.1-1.0-1.00.11.10.30.5-1.1-1.11.1
Delta time to tail flick, vehicle, before/after SA1.91.93.30.7-0.71.71.3-1.3-0.3-0.30.4-0.4-1.7-1.71.6-1.81.81.71.8-0.4-1.8-0.7-0.91.81.8-1.8
Delta time to tail flick, test, before/after SA0.50.41.0-0.30.30.40.1-0.10.50.5-0.50.5-0.5-0.60.4-0.70.60.60.7-0.8-0.7-0.9-1.01.01.0-1.0
Tibia length0.51.52.9-1.61.7-1.0-1.51.51.71.7-1.71.70.90.8-1.20.6-0.7-0.9-0.5-1.60.6-1.4-1.30.20.2-0.2
Ambulatory time before self-admin0.10.10.20.5-0.50.20.4-0.4-0.5-0.40.5-0.5-0.2-0.10.3-0.10.10.20.00.5-0.10.50.4-0.1-0.10.1
Ambulatory time after self-admin0.40.40.8-0.80.8-0.8-0.80.80.70.9-0.70.70.70.7-0.80.7-0.6-0.7-0.7-0.50.6-0.4-0.3-0.3-0.30.3
Bone: tissue strength1.21.22.51.5-1.50.81.4-1.4-1.6-1.61.4-1.4-0.8-0.71.1-0.60.50.80.41.5-0.51.31.2-0.2-0.20.2
Total heroin consumption1.41.62.5-1.51.5-1.5-1.61.61.41.4-1.61.61.31.3-1.51.2-1.3-1.3-1.1-1.11.2-0.8-0.6-0.6-0.60.6
Bone: trabecular number1.93.05.5-1.11.1-2.1-2.12.10.70.8-0.60.62.12.2-2.32.2-2.2-2.3-2.20.12.30.50.8-1.9-1.91.9
Bone: trabecular spacing3.14.07.60.7-0.62.32.0-2.0-0.1-0.10.1-0.1-2.4-2.52.4-2.62.52.72.6-0.9-2.8-1.4-1.72.62.6-2.6
Bone: trabecular thickness5.06.011.9-0.10.1-2.5-1.91.9-0.7-0.60.7-0.72.62.8-2.63.0-3.0-3.0-3.11.93.32.52.8-3.5-3.53.5
Bone: trabecular tissue density2.43.35.41.9-1.92.32.2-2.2-1.7-1.81.4-1.4-2.3-2.22.3-2.22.12.22.01.0-2.00.50.21.41.4-1.4
Water consumed over 24 hours0.60.71.90.8-0.8-0.2-0.10.1-1.0-1.01.0-1.00.30.4-0.40.5-0.4-0.6-0.61.30.81.41.4-1.1-1.11.1
Number of responses in last shaping day0.10.10.2-0.40.4-0.4-0.40.40.30.3-0.40.40.40.3-0.40.3-0.4-0.3-0.3-0.20.3-0.2-0.1-0.2-0.20.2