Hub : Genes

Alg8

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS XM_039105968.1 0.03 0.02 4.6e-03 0 0.01 -0 -0 2.8e-01 6.6e-02 8.0e-01 4.6e-01
2 NAcc mRNA stability Alg8 0.11 0.06 3.3e-13 0.11 0.12 0.12 0.11 1.4e-12 2.1e-13 2.5e-13 5.7e-13
3 NAcc gene expression Alg8 0.12 0.06 5.1e-12 0.1 0.1 0.1 0.1 2.8e-11 9.6e-12 1.6e-11 9.3e-12
4 Brain isoform ratio XM_039105983.1 0.11 0.06 2.1e-10 0.1 0.11 0.1 0.1 6.0e-10 4.6e-10 5.3e-10 6.9e-10
5 BLA mRNA stability Alg8 0.16 0.08 6.6e-08 0.13 0.13 0.13 0.13 2.6e-07 3.1e-07 2.5e-07 1.6e-07
6 BLA gene expression Alg8 0.38 0.16 2.2e-15 0.27 0.23 0.23 0.26 9.6e-15 8.1e-13 1.3e-12 2.2e-14
7 BLA alternative TSS XM_039105978.1 0.06 0.04 2.7e-03 0.03 0.02 0.02 0.02 1.0e-02 3.2e-02 4.3e-02 4.4e-02
8 PL mRNA stability Alg8 0.09 0.05 8.0e-09 0.08 0.07 0.07 0.08 2.8e-09 4.7e-08 1.9e-08 8.4e-09
9 Adipose mRNA stability Alg8 0.41 0.17 0.0e+00 0.13 0.12 0.12 0.12 6.8e-14 1.1e-12 1.9e-13 8.6e-13
10 Liver gene expression Alg8 0.09 0.05 1.7e-08 0.03 0.05 0.04 0.04 3.2e-04 3.5e-06 2.2e-05 5.0e-05
11 Adipose isoform ratio NM_001034127.1 0.03 0.02 3.4e-03 0.01 0.01 0.01 0.01 7.4e-03 2.0e-02 1.0e-02 2.1e-02
12 Brain mRNA stability Alg8 0.15 0.07 6.2e-15 0.16 0.15 0.14 0.15 8.8e-15 6.6e-14 8.1e-13 3.3e-14
13 Adipose alternative TSS XM_039105971.1 0.05 0.03 5.2e-05 0.03 0.02 0.03 0.03 3.1e-04 9.1e-04 7.5e-04 3.1e-04
14 Adipose isoform ratio XM_039105978.1 0.13 0.06 4.4e-13 0.09 0.08 0.08 0.08 3.3e-10 2.8e-09 7.5e-09 3.6e-09
15 Adipose alternative TSS NM_001034127.1 0.04 0.03 3.3e-03 0.02 0 0.01 0 5.2e-03 1.1e-01 1.7e-02 7.8e-02
16 Adipose alternative TSS XM_039105978.1 0.13 0.07 1.6e-12 0.08 0.08 0.08 0.08 1.9e-09 1.6e-09 7.6e-09 2.7e-09
17 LHb isoform ratio NM_001034127.1 0.23 0.13 2.6e-03 0.04 0.06 0.03 0.04 5.1e-02 1.2e-02 6.1e-02 4.1e-02
18 PL gene expression Alg8 0.14 0.08 1.7e-12 0.12 0.12 0.12 0.11 1.4e-12 4.7e-13 1.0e-12 1.7e-12
19 pVTA gene expression Alg8 0.13 0.08 1.8e-04 0.07 0.08 0.09 0.09 5.2e-04 2.4e-04 9.6e-05 1.2e-04
20 Adipose gene expression Alg8 0.26 0.15 2.3e-07 0.03 0.03 0.04 0.04 1.5e-04 1.1e-04 2.3e-05 6.2e-05
21 BLA isoform ratio XR_005501993.1 0.13 0.1 1.8e-03 0.02 0.04 0.04 0.04 2.8e-02 3.1e-03 4.8e-03 4.8e-03
22 LHb mRNA stability Alg8 0.23 0.15 6.3e-03 0.11 0.05 0.04 0.09 1.5e-03 2.6e-02 4.4e-02 3.8e-03
23 Brain gene expression Alg8 0.11 0.07 2.0e-08 0.06 0.08 0.08 0.08 7.6e-06 4.5e-08 4.0e-08 9.8e-08
24 LHb gene expression Alg8 0.18 0.11 8.6e-03 0.01 0.05 0.01 0.03 1.5e-01 2.1e-02 1.7e-01 5.3e-02
25 pVTA isoform ratio NM_001034127.1 0.08 0.06 6.5e-03 0.06 0.05 0.05 0.05 9.4e-04 3.8e-03 4.4e-03 2.5e-03
26 BLA isoform ratio NM_001034127.1 0.18 0.11 2.1e-04 0.01 0.03 0.04 0.01 4.8e-02 1.3e-02 3.3e-03 1.1e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.10.10.4-0.20.20.4-0.20.4-0.4-0.4-0.4-0.50.00.3-0.40.3-0.30.50.30.10.3-0.6-0.40.1-0.7-0.40.6-0.5-0.2
Area under the delay curve0.91.01.6-1.31.21.2-1.10.9-1.2-0.8-0.8-1.2-0.91.1-1.11.1-1.11.11.00.80.9-1.0-0.8-0.6-1.2-1.00.90.1-0.0
BMI with tail1.34.47.41.4-1.7-1.71.8-2.42.02.52.52.31.6-2.12.4-2.12.1-2.1-2.2-2.0-2.52.22.72.01.12.1-1.92.31.9
BMI without tail7.114.719.93.1-3.4-3.73.4-3.84.13.93.94.12.6-4.24.2-4.24.2-4.2-4.1-3.4-4.54.44.22.83.14.3-4.23.82.9
Body weight3.012.721.12.3-2.8-3.02.9-3.83.64.04.03.92.4-3.53.9-3.63.6-3.6-3.8-3.3-4.34.04.63.22.13.9-3.54.33.2
Weight adjusted by age0.50.52.30.3-0.3-0.70.1-0.20.70.10.10.4-0.5-0.80.5-0.70.8-0.8-0.40.2-0.71.50.3-0.61.31.0-1.50.7-0.5
Bone surface0.91.73.1-1.51.51.3-1.61.5-1.4-1.4-1.4-1.3-1.81.2-1.31.2-1.21.41.41.71.1-0.6-1.2-1.6-0.6-0.50.5-0.5-1.3
Bone volume0.40.71.5-1.11.10.9-1.11.0-0.9-0.9-0.9-0.9-1.20.7-0.80.7-0.71.00.81.10.6-0.3-0.7-1.0-0.6-0.20.20.1-0.7
Breakpoint value in progressive ratio session0.30.30.6-0.40.50.5-0.50.5-0.6-0.5-0.5-0.5-0.40.7-0.60.7-0.70.80.60.50.7-0.7-0.6-0.4-0.4-0.60.6-0.7-0.6
Number of licking bursts2.12.43.71.7-1.7-1.51.8-1.71.61.61.61.81.9-1.61.8-1.61.6-1.5-1.7-1.9-1.51.01.81.90.91.1-0.70.61.3
Context. condit. distance diff. score3.84.66.5-2.22.32.1-2.42.3-2.3-2.2-2.2-2.1-2.52.2-2.22.2-2.22.22.42.52.3-1.6-2.2-2.5-1.1-1.31.4-1.6-2.1
Locomotion velocity, session 11.81.93.1-1.11.21.2-1.21.6-1.4-1.6-1.6-1.6-1.01.4-1.61.4-1.41.41.41.21.6-1.5-1.7-1.2-1.0-1.61.4-1.3-1.0
Locomotion distance, session 10.60.81.5-0.80.90.8-0.90.9-1.0-0.9-0.9-0.9-1.01.0-0.90.9-1.00.91.01.11.2-0.7-1.0-1.2-0.1-0.80.6-0.8-0.8
Locomotion velocity, session 20.50.61.1-0.80.90.7-0.91.0-0.7-1.0-1.0-1.0-0.90.7-0.90.7-0.70.80.80.90.7-0.4-1.0-0.9-0.5-0.70.3-0.2-0.6
Locomotion distance, session 20.00.10.5-0.10.00.10.10.00.10.00.00.00.2-0.10.0-0.10.1-0.0-0.2-0.3-0.2-0.00.30.4-0.4-0.30.10.70.7
Locomotion velocity, session 30.40.40.7-0.70.70.7-0.70.8-0.7-0.8-0.8-0.7-0.60.6-0.70.7-0.60.60.70.70.6-0.6-0.7-0.6-0.6-0.50.5-0.4-0.5
Locomotion distance, session 32.93.23.9-1.81.91.8-1.92.0-1.9-2.0-2.0-1.9-1.81.9-1.91.9-1.91.72.01.91.9-1.6-1.9-1.8-1.2-1.51.4-1.2-1.5
Stereotopy head waving bouts, day 33.03.66.02.5-2.4-2.32.2-2.12.12.02.01.92.1-2.11.8-2.12.1-1.9-2.0-1.9-1.91.61.41.71.71.4-1.40.20.7
Stereotopy head waving duration, day 30.20.31.40.3-0.3-0.10.5-0.30.30.20.20.20.9-0.30.1-0.30.3-0.1-0.5-0.9-0.5-0.20.51.2-0.8-0.30.30.61.0
Locomotion velocity, session 70.50.50.8-0.70.80.7-0.80.9-0.8-0.9-0.9-0.8-0.70.7-0.70.7-0.70.50.80.70.7-0.6-0.7-0.6-0.4-0.80.6-0.4-0.6
Locomotion distance, session 70.50.61.6-1.01.00.8-1.10.8-0.9-0.7-0.7-0.7-1.30.8-0.60.8-0.80.50.91.10.7-0.1-0.6-1.20.0-0.30.1-0.1-0.9
Stereotopy head waving bouts, day 70.30.31.2-0.00.20.1-0.30.5-0.4-0.5-0.5-0.6-0.30.4-0.70.4-0.40.60.60.50.6-0.5-1.0-0.5-0.1-0.70.4-1.1-1.0
Stereotopy head waving duration, day 70.20.30.5-0.50.50.5-0.50.7-0.5-0.7-0.7-0.7-0.50.4-0.70.4-0.40.60.50.50.5-0.5-0.7-0.5-0.5-0.50.4-0.3-0.5
Locomotion velocity, session 88.09.613.1-3.53.53.6-3.43.5-3.5-3.5-3.5-3.5-3.03.1-3.23.2-3.13.13.23.03.0-2.8-2.9-2.4-3.1-2.72.6-1.2-1.9
Locomotion distance, session 81.62.43.1-1.71.81.7-1.81.8-1.7-1.7-1.7-1.7-1.71.6-1.61.6-1.61.61.61.71.5-1.2-1.5-1.6-1.2-1.11.1-0.7-1.2
Degree of sensitization distance1.91.93.81.0-1.1-1.31.0-1.41.31.51.51.50.6-1.41.6-1.51.4-1.5-1.4-0.9-1.51.91.50.51.71.7-1.81.30.7
Degree of sensitization stereotypy2.83.14.8-1.51.61.5-1.81.9-1.8-1.9-1.9-1.9-1.71.7-1.91.7-1.71.81.91.91.9-1.5-2.2-1.9-0.9-1.61.3-1.7-1.9
Conditioned locomotion0.20.31.4-0.40.40.6-0.10.4-0.3-0.4-0.4-0.50.20.5-0.50.5-0.50.50.2-0.20.3-0.8-0.00.5-1.2-0.60.90.30.8
Cocaine response after cond. corrected0.10.10.8-0.00.1-0.2-0.2-0.2-0.10.20.20.3-0.50.20.10.1-0.20.10.20.50.20.50.1-0.70.90.8-0.4-0.2-0.4
Cocaine response after cond. not corrected0.20.20.9-0.10.20.0-0.40.1-0.4-0.0-0.00.1-0.70.5-0.20.4-0.50.40.50.70.60.1-0.3-0.90.80.4-0.0-0.8-0.9
Cocaine response before conditioning0.20.22.20.4-0.2-0.10.10.1-0.2-0.2-0.2-0.20.20.1-0.20.2-0.10.10.30.20.5-0.6-0.7-0.20.2-0.60.5-1.5-0.9
Saline control response0.30.44.0-0.60.40.3-0.1-0.00.20.10.10.1-0.1-0.20.3-0.20.2-0.2-0.4-0.3-0.60.50.90.4-0.50.7-0.42.01.4
Bone: connectivity density1.11.72.9-0.91.11.1-1.21.3-1.4-1.4-1.4-1.4-1.01.2-1.41.3-1.21.31.51.31.5-1.4-1.7-1.2-0.8-1.21.2-1.7-1.5
Bone: cortical apparent density0.30.41.10.4-0.5-0.30.7-0.50.60.50.50.50.8-0.60.6-0.60.6-0.4-0.7-0.9-0.70.20.80.9-0.20.4-0.20.81.0
Bone: cortical area0.10.20.6-0.50.40.2-0.5-0.0-0.10.20.20.2-0.8-0.10.4-0.10.1-0.30.00.4-0.20.80.4-0.50.50.8-0.70.7-0.3
Bone: cortical porosity0.10.10.50.1-0.0-0.0-0.00.1-0.2-0.2-0.2-0.10.00.2-0.30.2-0.20.20.30.20.4-0.3-0.4-0.20.1-0.30.3-0.7-0.3
Bone: cortical porosity0.10.10.90.4-0.2-0.30.10.1-0.0-0.2-0.2-0.10.10.1-0.20.1-0.10.00.20.20.4-0.2-0.5-0.30.5-0.20.2-0.9-0.6
Bone: cortical thickness0.10.20.40.4-0.4-0.30.3-0.40.20.40.40.50.2-0.40.7-0.40.4-0.6-0.3-0.2-0.30.50.50.10.60.6-0.40.1-0.0
Bone: cortical thickness0.91.13.5-1.01.00.8-1.30.9-1.1-0.9-0.9-0.7-1.61.0-0.71.0-1.00.71.21.61.2-0.2-0.9-1.90.6-0.10.2-0.9-1.4
Bone: cortical tissue density0.30.41.10.5-0.5-0.30.7-0.50.60.40.40.40.8-0.60.6-0.60.6-0.4-0.7-0.9-0.70.20.70.9-0.20.4-0.20.71.0
Condit. Reinf. active minus inactive responses1.01.12.50.4-0.6-0.80.6-0.91.01.11.11.10.3-1.11.1-1.11.1-1.3-1.0-0.7-1.21.51.30.50.91.5-1.31.61.0
Condit. Reinf. active-inactive response ratio1.11.22.60.5-0.7-0.80.7-1.11.01.21.21.20.4-1.01.2-1.11.0-1.3-1.1-0.8-1.31.51.50.70.91.6-1.31.61.2
Condit. Reinf. active responses0.81.01.70.6-0.8-0.80.8-0.90.90.90.91.00.6-1.21.0-1.11.1-1.3-1.1-0.9-1.11.21.10.70.71.1-1.11.21.0
Condit. Reinf. inactive responses0.00.00.10.2-0.2-0.10.2-0.00.10.00.0-0.00.2-0.30.0-0.20.3-0.2-0.1-0.1-0.1-0.0-0.10.10.0-0.2-0.1-0.00.0
Incentive salience index mean0.20.31.10.0-0.1-0.30.1-0.30.40.40.40.4-0.3-0.50.5-0.50.5-0.7-0.4-0.0-0.61.00.5-0.20.70.9-1.01.00.2
Condit. Reinf. lever presses0.40.60.9-0.90.90.8-0.91.0-0.7-0.9-0.9-0.9-1.00.6-0.80.7-0.60.60.80.90.6-0.4-0.9-0.9-0.6-0.60.3-0.1-0.7
Condit. Reinf. active minus inactive responses0.81.03.9-1.71.51.2-1.60.9-0.9-0.6-0.6-0.7-2.00.6-0.40.7-0.70.40.81.40.40.5-0.1-1.6-0.10.5-0.61.4-0.2
Condit. Reinf. active-inactive response ratio0.91.02.5-1.61.41.3-1.41.1-1.1-0.9-0.9-1.0-1.60.9-0.81.0-0.90.81.01.30.8-0.2-0.5-1.3-0.6-0.30.20.6-0.4
Condit. Reinf. active responses0.71.04.3-1.81.41.0-1.50.7-0.6-0.3-0.3-0.4-2.00.4-0.10.4-0.50.20.51.3-0.01.10.4-1.50.21.0-1.12.10.1
Condit. Reinf. inactive responses0.60.73.5-0.1-0.1-0.40.1-0.50.80.60.60.7-0.3-0.70.8-0.70.7-0.8-0.7-0.2-1.01.51.0-0.00.71.4-1.41.90.7
Condit. Reinf. lever presses4.56.115.2-3.93.53.4-3.32.7-2.7-2.4-2.4-2.5-3.32.6-2.22.6-2.62.42.42.61.8-1.3-1.1-2.3-2.4-1.01.21.4-0.4
Condit. Reinf. lever reinforcers received0.91.35.5-2.01.71.3-1.81.0-0.9-0.6-0.6-0.6-2.30.7-0.30.7-0.70.50.81.60.30.90.1-1.90.10.9-0.91.8-0.2
Conditioned reinforcement - actives3.93.98.9-1.51.71.4-2.11.3-2.0-1.0-1.0-2.0-2.32.0-2.02.0-1.91.92.32.62.3-1.4-2.7-2.7-0.2-1.31.1-2.6-3.0
Conditioned reinforcement - inactives0.10.10.90.3-0.1-0.2-0.00.3-0.0-0.5-0.5-0.0-0.10.2-0.30.2-0.30.30.20.20.1-0.0-0.4-0.20.3-0.40.1-0.9-0.9
Conditioned locomotion3.54.28.4-1.51.71.6-2.11.9-2.1-1.9-1.9-2.1-2.12.0-2.22.1-2.12.12.32.52.3-1.6-2.7-2.4-0.6-1.61.3-2.6-2.9
Patch foraging indifference point 0 sec0.40.62.1-1.41.21.2-1.10.8-0.7-0.6-0.6-0.6-1.10.8-0.40.7-0.70.70.60.70.3-0.10.1-0.6-0.80.10.21.20.3
Patch foraging indifference point AUC0.00.00.2-0.20.20.1-0.2-0.1-0.00.30.30.0-0.40.10.20.0-0.00.00.10.30.00.30.0-0.40.30.3-0.30.2-0.1
Delay disc. indifference point, 0s delay0.20.31.1-0.10.2-0.0-0.40.6-0.1-0.7-0.7-0.1-0.80.1-0.10.1-0.10.10.30.70.20.5-0.5-1.00.80.2-0.5-0.4-1.1
Delay disc. indifference point, 16s delay1.31.33.9-1.41.31.5-0.91.1-1.3-1.1-1.1-1.3-0.41.2-1.21.2-1.21.20.90.41.0-1.6-0.5-0.0-2.0-1.41.50.50.9
Delay disc. indifference point, 2s delay0.60.71.1-0.80.90.7-1.00.8-0.9-0.8-0.8-0.9-1.00.8-0.80.8-0.80.80.91.00.7-0.4-0.9-0.9-0.4-0.60.4-0.5-1.0
Delay disc. indifference point, 24s delay0.40.42.1-0.70.60.7-0.3-0.2-0.50.50.5-0.50.10.5-0.50.5-0.50.50.2-0.20.3-0.90.10.5-1.5-0.70.90.61.0
Delay disc. indifference point, 4s delay0.40.41.3-1.00.90.8-1.00.6-0.6-0.4-0.4-0.6-1.10.6-0.60.6-0.60.60.60.90.3-0.0-0.4-0.8-0.5-0.1-0.10.4-0.5
Delay disc. indifference point, 8s delay1.21.32.1-1.51.41.4-1.30.9-1.4-0.6-0.6-1.4-1.01.3-1.31.3-1.31.31.11.01.1-1.2-0.9-0.8-1.4-1.01.10.10.1
Indifference point function ln k0.60.82.2-1.01.01.1-0.70.8-1.0-0.8-0.8-1.0-0.30.9-1.11.0-1.00.80.80.40.8-1.3-0.5-0.0-1.5-1.11.3-0.00.3
Indifference point function log k0.60.82.2-1.01.01.1-0.70.8-1.0-0.8-0.8-1.0-0.30.9-1.11.0-1.00.80.80.40.8-1.3-0.5-0.0-1.5-1.11.3-0.00.3
Patch foraging total patch changes 0 sec0.40.72.3-1.51.31.3-1.20.8-0.9-0.7-0.7-0.7-1.10.9-0.60.8-0.80.80.70.80.4-0.30.0-0.6-0.9-0.00.31.10.3
Patch foraging total patch changes 12 sec0.20.20.9-0.10.1-0.1-0.40.10.10.10.10.1-0.8-0.10.4-0.10.1-0.20.10.6-0.10.9-0.0-0.90.90.9-1.00.1-0.8
Patch foraging total patch changes 18 sec0.20.31.2-0.90.70.6-0.80.7-0.3-0.5-0.5-0.3-1.10.3-0.30.2-0.20.30.30.80.10.4-0.2-1.00.10.5-0.60.9-0.0
Patch foraging total patch changes 24 sec0.20.31.2-0.10.1-0.1-0.40.10.10.10.10.1-0.9-0.00.2-0.10.10.10.10.7-0.00.8-0.2-1.11.00.9-1.00.2-0.6
Patch foraging total patch changes 6 sec0.10.20.9-0.60.50.6-0.20.2-0.3-0.1-0.1-0.20.10.40.10.3-0.40.30.0-0.2-0.0-0.30.60.5-0.9-0.20.50.80.9
Patch foraging time to switch 0 sec1.21.94.92.2-2.0-1.91.9-1.41.61.11.11.51.9-1.41.3-1.41.4-1.2-1.3-1.5-1.00.70.81.41.40.5-0.5-0.90.2
Patch foraging water rate 0 sec1.21.93.8-1.91.81.7-1.81.4-1.5-1.2-1.2-1.4-1.91.5-1.41.5-1.51.31.51.71.2-0.8-1.0-1.6-1.0-0.60.60.1-0.7
Patch foraging water rate 12 sec1.21.83.9-2.01.81.7-1.51.4-1.3-1.2-1.2-1.5-1.21.4-1.51.4-1.41.51.21.01.0-1.3-0.8-0.6-2.0-1.21.10.70.4
Patch foraging water rate 18 sec0.40.61.6-1.31.10.8-0.90.8-0.4-0.7-0.7-0.7-0.90.8-1.00.8-0.80.80.50.50.3-0.2-0.1-0.4-0.9-0.20.31.30.7
Patch foraging water rate 24 sec1.92.65.2-1.91.81.8-1.61.6-1.6-1.5-1.5-1.8-1.11.9-2.21.9-1.92.01.51.11.4-1.8-1.2-0.6-2.3-1.81.70.10.1
Patch foraging water rate 6 sec1.11.52.6-1.41.31.5-1.21.4-1.4-1.5-1.5-1.4-0.91.2-1.51.3-1.31.31.20.91.2-1.4-1.1-0.6-1.6-1.31.3-0.2-0.1
Seeking ratio, delayed vs. immediate footshock0.10.10.80.3-0.2-0.40.0-0.20.30.10.10.1-0.20.2-0.10.1-0.20.20.20.30.20.1-0.3-0.50.80.1-0.1-0.9-0.8
Distance traveled before self-admin0.10.10.20.2-0.3-0.20.3-0.40.20.50.50.40.3-0.20.0-0.30.3-0.3-0.3-0.3-0.30.10.40.40.00.2-0.10.20.3
Distance traveled after self-admin0.30.41.40.7-0.7-0.40.8-0.60.30.60.60.51.2-0.40.2-0.50.5-0.4-0.5-1.0-0.3-0.50.51.2-0.4-0.20.5-0.30.7
Extensor digitorum longus weight0.20.84.3-0.1-0.2-0.30.3-0.80.60.90.90.90.3-0.70.9-0.70.7-0.7-0.9-0.7-1.21.11.60.90.11.1-0.92.11.3
Bone: elastic displacement0.10.10.40.1-0.00.20.2-0.1-0.10.10.1-0.00.40.1-0.10.1-0.20.10.0-0.30.2-0.50.20.5-0.4-0.50.6-0.20.3
Bone: elastic work0.60.82.5-0.50.60.9-0.40.8-1.0-0.9-0.9-0.80.10.9-0.80.9-0.90.70.80.21.0-1.5-0.60.2-1.3-1.41.6-1.0-0.1
Bone: endosteal estimation0.20.31.5-0.70.60.3-0.80.3-0.1-0.1-0.1-0.2-1.2-0.0-0.10.00.00.10.20.8-0.10.8-0.2-1.10.40.6-1.00.8-0.5
Bone: endosteal perimeter0.61.23.6-1.71.61.2-1.61.2-0.9-1.0-1.0-1.1-1.90.8-1.10.9-0.81.21.01.50.50.0-0.9-1.5-0.7-0.3-0.20.8-0.7
Epididymis fat weight3.68.315.42.6-2.7-3.32.3-3.73.13.93.93.21.4-2.82.9-2.92.8-2.9-2.7-1.8-3.13.62.61.33.33.4-3.41.60.6
Delta time in closed arm before/after self-admin0.90.87.6-0.80.40.50.0-0.10.10.30.30.20.2-0.40.4-0.40.5-0.4-0.7-0.8-0.90.31.41.0-1.10.6-0.32.82.4
Delta time in open arm before/after self-admin0.40.41.5-0.50.60.3-0.80.3-0.5-0.2-0.2-0.3-1.20.6-0.50.5-0.50.60.61.10.40.2-0.6-1.20.40.3-0.4-0.4-1.2
Diff in mean of infusions in LGA sessions1.71.94.91.4-1.5-1.21.7-1.41.51.21.21.32.0-1.31.4-1.31.2-1.4-1.5-1.9-1.50.61.62.20.00.6-0.30.81.5
Delay discount exponential model param0.90.91.61.3-1.2-1.21.0-0.81.20.60.61.20.8-1.11.1-1.11.1-1.1-1.0-0.8-0.91.10.70.51.31.0-1.0-0.1-0.1
Extinction: sum of active levers before priming0.10.10.6-0.30.20.1-0.20.00.00.00.00.1-0.30.10.10.1-0.10.0-0.10.1-0.20.30.3-0.1-0.10.4-0.30.70.3
Active lever presses in extinction session 60.70.71.6-0.40.60.4-0.70.6-0.8-0.6-0.6-0.5-0.81.0-0.81.0-1.11.11.01.01.1-0.6-1.0-1.20.2-0.50.6-1.3-1.2
Bone: final force0.30.41.1-0.80.80.8-0.80.7-1.0-0.7-0.7-0.5-0.70.7-0.40.7-0.70.60.70.70.7-0.6-0.3-0.5-0.5-0.40.7-0.4-0.5
Bone: final moment0.20.40.9-0.80.80.8-0.80.7-1.0-0.7-0.7-0.5-0.70.7-0.40.6-0.70.50.70.70.6-0.5-0.3-0.5-0.5-0.30.5-0.4-0.6
Food consumed during 24 hour testing period2.02.44.3-1.31.41.4-1.51.9-1.4-2.0-2.0-2.0-1.21.4-2.01.5-1.41.61.51.41.4-1.6-2.1-1.1-1.7-1.61.2-1.0-1.2
Glucose0.40.61.5-1.01.01.0-0.90.8-0.8-0.8-0.8-0.9-0.70.9-0.80.9-0.80.70.80.70.5-0.7-0.5-0.3-1.2-0.60.7-0.0-0.4
Heart weight0.50.71.7-1.21.10.9-1.20.4-0.8-0.1-0.1-0.8-1.31.0-0.81.0-1.01.10.91.10.9-0.3-0.6-1.3-0.4-0.20.30.1-0.4
Delay discount hyperbolic model param0.90.91.61.2-1.2-1.21.1-0.81.20.60.61.21.0-1.11.1-1.11.1-1.1-1.0-0.9-0.90.90.80.81.10.9-0.8-0.00.3
Intermittent access intake day 1-15 change2.32.33.2-1.61.61.5-1.71.0-1.7-0.7-0.7-1.7-1.61.8-1.81.8-1.81.81.71.71.6-1.4-1.6-1.4-1.2-1.61.2-0.9-1.4
Intermittent access intake escalation2.52.53.5-1.71.81.6-1.81.1-1.8-0.7-0.7-1.8-1.71.9-1.91.8-1.91.91.81.81.7-1.4-1.6-1.5-1.2-1.61.2-0.8-1.3
Intermittent access intake escalation 20.40.41.7-0.30.40.2-0.7-0.2-0.50.50.5-0.5-0.90.5-0.50.5-0.50.50.60.90.5-0.0-0.8-1.00.3-0.2-0.1-0.8-1.3
Intermitt. access day 1 inactive lever presses0.50.62.21.2-1.0-1.30.7-0.70.60.60.60.70.4-0.70.6-0.50.5-0.5-0.4-0.2-0.30.7-0.1-0.11.50.5-0.7-1.0-0.9
Intermitt. access day 15 inactive lever presses0.10.10.6-0.10.10.2-0.10.60.0-0.8-0.80.0-0.00.4-0.30.3-0.30.30.10.10.1-0.2-0.10.1-0.1-0.60.3-0.2-0.3
Intermitt. access escalation Index0.20.20.70.3-0.3-0.00.40.40.2-0.7-0.70.20.6-0.10.2-0.20.2-0.2-0.3-0.6-0.4-0.20.30.9-0.5-0.40.3-0.10.2
Intermittent access day 1 total infusions0.70.92.1-1.01.01.0-1.11.3-0.8-1.4-1.4-0.8-1.20.9-0.80.8-0.80.80.91.10.6-0.3-0.8-1.1-0.4-0.30.2-0.3-0.9
Intermittent access day 15 total infusions3.43.95.4-2.12.12.0-2.31.7-2.1-1.5-1.5-2.1-2.22.2-2.22.2-2.22.22.22.31.9-1.5-2.1-2.0-1.3-1.61.3-1.3-2.1
Intermittent access terminal intake (last 3 days)1.51.74.0-1.21.31.1-1.61.0-1.3-0.8-0.8-1.3-1.71.4-1.41.3-1.31.31.51.81.2-0.7-1.6-1.6-0.4-0.80.5-1.2-2.0
Intermittent access total infusions1.21.34.5-0.81.00.7-1.31.0-1.0-0.9-0.9-1.0-1.61.1-1.11.0-1.01.01.31.71.0-0.3-1.5-1.60.1-0.40.2-1.4-2.1
Intermittent access day 1 locomotion1.01.03.5-0.30.50.6-0.81.1-0.9-1.3-1.3-1.0-0.80.8-0.90.8-0.80.81.11.11.0-0.7-1.5-1.0-0.1-0.70.6-1.9-1.9
Intermittent access day 15 total locomotion1.21.32.3-1.11.21.0-1.41.0-1.2-0.9-0.9-1.1-1.51.2-1.21.1-1.11.11.31.51.1-0.6-1.3-1.5-0.3-0.70.5-0.9-1.5
Intermittent access total locomotion0.60.63.0-0.50.60.5-0.90.6-0.7-0.6-0.6-0.7-1.10.6-0.70.6-0.60.60.91.20.6-0.2-1.1-1.20.1-0.20.1-1.1-1.7
Intermittent access standard deviation0.20.21.10.3-0.2-0.5-0.1-0.40.20.50.50.2-0.40.00.00.0-0.10.10.10.4-0.00.5-0.3-0.60.80.3-0.5-0.7-1.1
Left kidney weight0.72.04.80.5-0.7-1.20.6-1.51.41.81.81.20.1-1.51.4-1.51.5-1.4-1.3-0.6-1.72.21.30.21.32.0-2.22.00.7
Right kidney weight0.82.24.20.8-1.0-1.31.0-1.61.61.81.81.40.5-1.51.5-1.61.6-1.5-1.5-1.0-1.72.01.60.71.21.8-1.92.01.1
Cocaine induced anxiety0.70.91.91.0-1.0-0.71.2-1.00.81.01.00.81.4-1.10.9-1.11.1-1.1-1.0-1.3-0.80.20.91.40.00.1-0.20.20.8
Post-drug Anxiety0.10.21.00.1-0.2-0.10.4-0.30.30.30.30.30.5-0.30.3-0.30.3-0.3-0.4-0.6-0.30.10.60.6-0.20.2-0.00.81.0
Baseline Anxiety1.71.83.0-1.71.61.4-1.61.7-1.3-1.7-1.7-1.3-1.71.5-1.61.5-1.51.51.41.51.2-0.7-1.0-1.5-0.7-0.50.60.2-0.4
Tail length2.88.617.11.8-2.1-2.72.0-2.73.12.92.93.01.0-3.13.1-3.23.2-3.2-3.0-1.9-3.54.13.11.22.83.9-4.03.72.0
Length with tail2.28.212.91.8-2.2-2.52.2-2.93.03.03.03.11.6-3.03.1-3.03.0-3.0-3.0-2.4-3.63.53.52.21.93.4-3.33.62.3
Length without tail0.10.31.5-0.10.00.30.2-0.3-0.00.30.30.20.70.10.10.1-0.10.0-0.3-0.7-0.3-0.40.81.2-1.1-0.30.60.60.9
Times rat made contact with spout1.11.31.91.3-1.3-1.31.3-1.11.41.01.01.01.2-1.41.0-1.31.4-1.0-1.3-1.2-1.41.10.91.20.60.9-1.00.70.7
Lifetime Intake1.41.64.1-1.01.10.9-1.41.2-1.1-1.2-1.2-1.1-1.71.3-1.21.1-1.11.11.41.81.2-0.5-1.6-1.90.1-0.50.3-1.3-2.0
Liver weight, left1.11.72.80.9-1.1-1.11.1-1.61.21.71.71.31.0-1.31.5-1.31.3-1.4-1.4-1.2-1.71.41.71.40.61.4-1.21.41.0
Liver weight, right6.110.214.03.3-3.3-3.43.1-3.53.33.43.43.42.7-3.53.7-3.53.5-3.6-3.3-2.9-3.63.43.22.72.73.3-3.11.51.3
Locomotor activity0.61.04.00.6-0.8-0.81.1-0.21.00.10.10.71.1-1.20.8-1.11.1-1.0-1.2-1.3-1.10.71.11.10.10.8-0.71.82.0
Locomotor testing distance0.40.74.4-0.0-0.2-0.40.30.10.6-0.0-0.00.6-0.1-1.00.7-0.90.9-0.8-0.8-0.4-0.81.20.9-0.00.71.2-1.32.11.4
Locomotor testing rearing2.13.26.11.2-1.4-1.61.4-1.11.91.11.11.90.8-2.22.0-2.12.1-2.0-1.9-1.4-2.12.52.00.81.82.3-2.42.41.6
Locomotion in novel chamber2.12.64.4-1.11.31.6-1.41.6-1.9-1.6-1.6-2.0-1.11.4-1.41.5-1.41.21.61.51.6-1.8-2.1-1.1-1.5-2.01.5-2.0-2.0
Locomotion in novel chamber post-restriction5.26.39.0-2.52.62.8-2.62.6-3.0-2.6-2.6-3.0-2.12.7-2.82.7-2.62.52.62.32.4-2.6-2.6-1.7-2.5-2.62.4-1.5-1.7
Fecal boli incidents, locomotor time 13.63.99.0-1.61.81.5-2.12.2-2.1-2.1-2.1-2.0-2.42.0-1.91.9-1.91.92.22.62.3-1.2-2.5-3.00.3-1.10.8-1.8-2.3
Change in fecal boli incidents, locomotor task1.51.54.71.0-1.1-0.71.4-1.11.01.01.01.11.9-1.11.1-1.11.1-1.2-1.3-1.9-1.20.11.52.2-0.60.20.11.01.9
Time >=10cm from walls, locomotor time 11.61.62.3-1.21.31.4-1.31.3-1.4-1.2-1.2-1.3-1.11.5-1.31.3-1.31.31.41.21.4-1.5-1.2-1.0-1.1-1.21.2-0.9-0.8
Bouts of movement, locomotor time 10.91.04.2-1.21.01.2-0.71.7-0.8-2.1-2.1-0.8-0.40.8-0.70.7-0.70.70.40.20.3-0.8-0.00.2-1.5-0.90.71.00.8
Total resting periods, locomotor time 11.31.45.4-1.21.11.5-0.81.9-1.1-2.3-2.3-1.1-0.41.1-1.01.0-1.01.00.70.30.6-1.2-0.30.2-1.8-1.31.20.70.6
Rest time, locomotor task time 11.11.22.1-1.21.21.4-1.01.1-1.3-1.0-1.0-1.3-0.61.3-1.21.2-1.21.21.00.61.0-1.3-0.9-0.3-1.5-1.41.3-0.30.1
Distance moved, locomotor task time 10.70.82.40.6-0.6-0.90.4-0.61.00.70.71.0-0.1-1.00.9-0.90.9-0.9-0.7-0.1-0.91.40.8-0.21.41.5-1.50.8-0.1
Vertical activity count, locomotor time 10.40.41.10.3-0.4-0.60.3-0.50.70.60.60.7-0.1-0.70.5-0.60.6-0.7-0.5-0.1-0.70.90.6-0.10.71.1-1.00.80.2
Time >=10cm from walls, locomotor time 20.30.41.3-0.70.70.5-0.90.3-0.5-0.1-0.1-0.4-1.10.7-0.50.5-0.50.50.71.00.5-0.0-0.6-1.10.20.1-0.1-0.3-0.9
Bouts of movement, locomotor time 20.20.22.0-0.0-0.00.20.11.00.1-1.4-1.40.20.0-0.20.2-0.30.3-0.3-0.2-0.2-0.40.30.30.2-0.10.2-0.30.40.2
Total resting periods, locomotor time 20.20.22.0-0.0-0.00.20.01.0-0.0-1.4-1.40.1-0.0-0.10.1-0.20.2-0.2-0.1-0.1-0.20.20.10.1-0.10.1-0.20.10.1
Rest time, locomotor task time 20.40.41.11.0-0.9-0.70.9-1.00.41.11.10.51.0-0.50.6-0.60.6-0.5-0.5-0.7-0.1-0.20.10.60.4-0.10.2-0.90.1
Distance moved, locomotor task time 20.50.62.4-0.60.60.1-1.00.4-0.2-0.3-0.3-0.2-1.60.3-0.40.3-0.30.30.51.30.10.9-0.4-1.50.90.8-1.00.2-1.3
Vertical activity count, locomotor time 20.30.41.6-0.20.2-0.3-0.4-0.20.30.30.30.2-1.0-0.30.1-0.20.1-0.2-0.00.7-0.41.20.1-1.01.01.1-1.30.7-0.5
Light reinforcement 11.42.63.71.9-1.9-1.81.8-1.61.81.41.41.91.6-1.61.9-1.71.6-1.8-1.7-1.6-1.51.51.61.31.71.5-1.20.40.8
Light reinforcement 20.10.10.60.6-0.5-0.50.4-0.20.20.10.10.30.3-0.30.5-0.20.2-0.5-0.1-0.1-0.00.20.00.00.70.1-0.1-0.8-0.5
Bone: marrow area0.10.31.2-0.60.50.2-0.70.2-0.0-0.0-0.0-0.1-1.1-0.10.0-0.00.10.00.10.7-0.20.9-0.1-0.90.50.7-1.00.8-0.4
Bone: maximum diameter0.40.72.3-1.41.31.0-1.30.8-0.8-0.6-0.6-0.6-1.50.7-0.50.7-0.70.60.71.10.30.2-0.2-1.0-0.40.1-0.20.8-0.5
Bone: maximum force0.71.32.6-1.31.31.5-1.31.3-1.6-1.3-1.3-1.1-1.01.1-0.91.1-1.11.01.21.11.1-1.1-0.8-0.7-1.2-0.91.1-0.6-0.8
Bone: maximum moment0.71.22.4-1.31.31.4-1.31.3-1.5-1.3-1.3-1.2-1.11.1-0.91.1-1.11.01.21.11.0-1.0-0.8-0.8-1.1-0.81.0-0.6-0.9
Mean time between licks in bursts0.40.63.1-0.30.2-0.4-0.60.10.40.00.00.1-1.3-0.40.1-0.30.4-0.2-0.00.9-0.51.6-0.2-1.41.31.2-1.80.7-1.0
Mean num. licks in bursts1.31.62.6-1.41.41.2-1.51.5-1.2-1.4-1.4-1.5-1.61.2-1.51.3-1.21.21.31.51.1-0.7-1.5-1.5-0.8-0.80.4-0.3-1.1
Cd content in liver0.60.60.90.8-0.8-0.80.8-0.90.80.90.90.90.6-0.80.9-0.80.8-0.8-0.8-0.7-0.80.90.80.50.80.9-0.80.50.5
Co content in liver0.30.31.3-0.70.60.3-0.80.6-0.2-0.5-0.5-0.4-1.10.2-0.40.2-0.20.20.40.90.10.5-0.5-1.10.30.2-0.70.6-0.6
Cu content in liver0.60.73.00.0-0.2-0.50.2-0.60.80.80.80.7-0.1-0.80.7-0.80.8-0.7-0.7-0.3-0.91.30.90.00.81.2-1.31.70.9
Fe content in liver0.40.51.9-0.40.50.2-0.80.5-0.5-0.4-0.4-0.4-1.10.5-0.40.5-0.50.40.71.10.70.1-0.7-1.40.70.0-0.2-0.8-1.3
K content in liver0.70.71.31.1-1.1-1.01.1-0.91.00.80.80.71.1-1.00.7-1.01.0-0.9-0.9-1.0-0.90.60.50.90.50.6-0.60.20.6
Mg content in liver0.00.00.0-0.10.0-0.0-0.0-0.10.10.10.1-0.0-0.0-0.1-0.0-0.10.10.0-0.1-0.0-0.10.10.0-0.0-0.00.2-0.10.20.2
Mn content in liver0.20.21.70.5-0.3-0.10.30.0-0.2-0.2-0.2-0.30.50.2-0.30.2-0.20.40.2-0.10.4-0.8-0.50.3-0.3-0.60.8-1.3-0.4
Na content in liver0.30.33.00.6-0.4-0.40.1-0.0-0.1-0.1-0.1-0.30.00.2-0.30.2-0.20.20.40.40.6-0.3-0.9-0.60.7-0.30.2-1.7-1.2
Rb content in liver0.20.32.2-1.00.70.7-0.50.3-0.2-0.2-0.2-0.2-0.40.2-0.20.2-0.20.20.00.0-0.20.00.40.2-0.90.20.01.50.9
Se content in liver0.60.82.61.6-1.4-1.31.3-1.00.80.80.80.71.3-0.80.6-0.80.8-0.7-0.7-0.9-0.30.10.10.71.00.2-0.1-1.10.0
Sr content in liver1.00.91.1-0.91.01.0-1.01.0-1.0-1.1-1.1-1.1-0.91.0-1.11.0-1.01.01.01.01.0-0.8-1.0-0.9-0.7-0.90.8-0.7-0.8
Zn content in liver0.30.31.3-0.90.80.5-0.80.5-0.3-0.4-0.4-0.3-1.20.3-0.30.3-0.30.30.40.80.20.4-0.2-1.00.20.4-0.50.7-0.2
Bone: minimum diameter0.40.72.70.1-0.2-0.50.1-0.50.70.70.70.7-0.4-0.90.9-0.90.9-0.9-0.70.0-0.91.60.7-0.41.11.4-1.61.30.1
Time in familiar zone, hab. session 10.00.00.1-0.10.20.1-0.20.2-0.1-0.2-0.2-0.3-0.20.2-0.10.2-0.20.20.20.30.2-0.1-0.3-0.2-0.1-0.10.1-0.2-0.4
Time in novel zone, hab. session 10.80.81.60.5-0.7-0.60.8-0.90.80.90.91.00.7-0.80.9-0.90.8-0.9-1.0-1.0-0.90.81.30.90.40.8-0.71.21.2
Total zone transitions, hab. session 10.30.42.1-0.20.20.60.20.3-0.5-0.4-0.4-0.30.80.3-0.10.3-0.30.20.0-0.60.3-1.10.21.1-1.4-1.11.30.00.9
Total locomotion distance, hab. session 17.210.213.93.7-3.6-3.73.4-3.63.43.53.53.52.9-3.43.5-3.43.4-3.5-3.3-2.9-3.13.22.92.33.42.9-2.91.11.5
Locomotion velocity, hab. session 16.18.712.63.5-3.4-3.53.2-3.33.23.23.23.32.6-3.13.2-3.13.1-3.2-3.0-2.6-2.82.92.52.03.42.7-2.70.71.1
Time in familiar zone, hab. session 20.20.20.7-0.70.60.5-0.50.6-0.3-0.6-0.6-0.5-0.50.2-0.40.3-0.20.50.20.3-0.1-0.1-0.2-0.1-0.8-0.2-0.10.80.2
Time in novel zone, hab. session 20.10.10.6-0.00.1-0.0-0.3-0.1-0.20.10.10.0-0.50.3-0.10.2-0.30.00.40.50.50.1-0.2-0.80.70.2-0.0-0.7-0.8
Total zone transitions, hab. session 20.30.41.7-0.60.50.9-0.20.3-0.6-0.4-0.4-0.30.30.5-0.20.4-0.50.30.2-0.30.3-0.90.30.7-1.3-1.01.10.40.9
Total locomotion distance, hab. session 25.26.98.62.7-2.7-2.82.7-2.92.72.92.92.92.2-2.82.9-2.82.8-2.9-2.7-2.4-2.62.72.71.92.72.5-2.51.61.7
Locomotion velocity, hab. session 25.87.89.62.8-2.9-2.92.8-3.12.93.13.13.12.4-2.93.1-2.92.9-3.0-3.0-2.7-2.82.82.92.22.62.6-2.51.92.0
Novel to familiar place preference ratio0.10.10.30.2-0.2-0.20.2-0.40.20.40.40.40.3-0.00.3-0.10.0-0.3-0.2-0.3-0.20.10.50.40.20.10.00.10.2
Novelty place preference0.00.00.20.0-0.0-0.10.1-0.30.10.30.30.20.10.10.10.0-0.1-0.1-0.1-0.1-0.10.10.40.20.10.00.00.20.2
Time in novel zone, NPP test0.00.00.1-0.30.30.2-0.2-0.0-0.10.00.0-0.0-0.10.3-0.10.3-0.30.10.10.00.1-0.10.20.1-0.3-0.20.20.30.2
Total zone transitions, NPP test0.81.12.0-1.11.11.4-0.91.1-1.3-1.1-1.1-1.1-0.51.1-1.01.1-1.11.21.00.61.2-1.4-0.7-0.4-1.4-1.41.4-0.4-0.0
Total locomotion distance, NPP test3.54.811.42.5-2.4-2.72.1-2.52.32.52.52.51.4-2.32.4-2.32.3-2.4-2.0-1.4-1.82.61.70.63.42.3-2.40.20.2
Locomotion velocity, NPP test4.46.213.92.9-2.8-3.12.5-2.82.62.82.82.81.7-2.62.8-2.62.6-2.6-2.3-1.7-2.12.81.90.83.72.6-2.60.20.3
Intraocular pressure5.77.911.4-3.13.13.2-3.03.3-3.0-3.4-3.4-3.1-2.73.0-3.03.0-3.03.02.92.72.7-2.5-2.5-2.2-2.7-2.62.3-1.0-1.6
Delta distance traveled before/after self-admin0.20.21.10.3-0.4-0.10.6-0.30.20.30.30.20.9-0.30.3-0.30.3-0.2-0.4-0.8-0.3-0.40.51.0-0.6-0.30.50.20.9
Delta ambulatory time before/after self-admin0.30.42.0-0.20.10.50.20.2-0.4-0.3-0.3-0.30.80.3-0.20.3-0.30.3-0.0-0.60.2-1.10.21.0-1.4-0.91.10.21.0
Parametrial fat weight2.44.67.41.8-2.0-1.82.1-2.52.02.52.52.32.0-2.22.6-2.12.1-2.3-2.3-2.3-2.31.92.72.21.22.0-1.51.82.1
Pavlov. Cond. lever latency0.50.61.30.9-0.9-0.71.0-0.90.80.90.90.91.2-0.60.7-0.70.6-0.6-0.8-1.1-0.60.31.01.10.30.2-0.10.30.9
Pavlov. Cond. magazine entry latency0.20.31.3-0.90.80.6-0.90.5-0.6-0.3-0.3-0.4-1.20.2-0.20.2-0.20.10.40.90.20.4-0.2-1.00.10.6-0.40.5-0.4
Pavlov. Cond. change in total contacts0.90.93.4-0.80.80.5-1.20.8-0.9-0.7-0.7-0.8-1.60.7-0.60.7-0.70.51.01.60.90.1-1.1-1.90.60.3-0.3-0.9-1.7
Pavlov. Cond. index score0.40.52.0-1.00.90.6-1.10.8-0.6-0.6-0.6-0.7-1.40.3-0.40.4-0.30.20.61.20.40.3-0.6-1.40.20.4-0.50.4-0.7
Pavlov. Cond. latency score0.40.51.9-0.90.80.6-1.00.7-0.6-0.6-0.6-0.6-1.40.4-0.40.4-0.40.30.61.20.40.3-0.6-1.30.20.4-0.50.2-0.9
Pavlov. Cond. lever contacts0.30.41.3-0.70.70.4-0.80.8-0.5-0.7-0.7-0.7-1.10.3-0.40.4-0.30.30.61.00.40.1-0.8-1.20.10.1-0.40.0-0.8
Pavlov. Cond. magazine entry number0.40.51.81.2-1.1-0.91.1-0.80.70.60.60.61.3-0.50.5-0.50.5-0.3-0.6-1.0-0.4-0.10.31.10.2-0.30.2-0.60.3
Pavlov. Cond. intertrial magazine entries0.50.71.51.2-1.1-1.11.1-0.81.00.80.80.81.0-0.90.7-0.90.9-0.8-0.8-0.8-0.70.50.30.60.80.4-0.6-0.20.2
Pavlov. Cond. lever-magazine prob. diff.0.40.51.9-0.90.90.6-1.00.8-0.7-0.7-0.7-0.7-1.40.4-0.50.4-0.40.30.71.20.50.2-0.8-1.30.10.3-0.40.1-0.8
Pavlov. Cond. response bias0.10.10.7-0.50.40.2-0.50.4-0.2-0.2-0.2-0.3-0.8-0.0-0.10.00.0-0.10.20.60.10.4-0.3-0.80.20.5-0.50.3-0.3
Pavlov. Cond. lever latency6.99.321.44.6-4.3-4.14.0-3.43.43.13.13.13.9-3.22.8-3.23.2-3.0-3.0-3.2-2.51.81.72.92.81.5-1.7-1.30.5
Pavlov. Cond. magazine entry latency5.15.910.4-3.23.13.1-2.92.7-2.8-2.6-2.6-2.5-2.62.6-2.42.6-2.62.42.52.32.4-2.1-1.6-2.0-2.3-1.82.0-0.1-0.6
Pavlov. Cond. change in total contacts3.85.312.6-3.63.33.1-3.12.5-2.6-2.2-2.2-2.3-3.12.5-2.02.4-2.42.22.32.51.9-1.2-1.1-2.3-2.0-1.01.21.1-0.4
Pavlov. Cond. index score6.78.518.2-4.34.03.8-3.83.3-3.3-3.0-3.0-3.0-3.73.1-2.73.1-3.12.92.93.12.6-1.9-1.8-2.9-2.6-1.51.70.7-0.8
Pavlov. Cond. latency score6.88.417.5-4.23.93.8-3.73.3-3.3-3.0-3.0-3.0-3.53.1-2.73.1-3.12.92.93.02.6-2.0-1.8-2.7-2.7-1.71.90.6-0.7
Pavlov. Cond. lever contacts5.87.919.4-4.44.03.8-3.73.1-3.1-2.8-2.8-2.9-3.63.0-2.62.9-2.92.82.72.92.2-1.6-1.3-2.6-2.8-1.31.51.6-0.2
Pavlov. Cond. magazine entry number9.411.420.14.5-4.3-4.24.2-3.83.83.53.53.64.0-3.63.3-3.63.6-3.4-3.5-3.7-3.22.52.63.32.92.1-2.20.21.6
Pavlov. Cond. intertrial magazine entries3.74.86.82.2-2.3-2.52.1-2.22.52.22.22.31.5-2.52.2-2.52.5-2.5-2.3-1.7-2.32.61.81.12.52.3-2.61.41.0
Pavlov. Cond. lever-magazine prob. diff.6.07.616.6-4.13.83.6-3.63.1-3.1-2.8-2.8-2.8-3.62.9-2.52.9-2.92.72.83.02.4-1.7-1.6-2.8-2.4-1.41.50.8-0.8
Pavlov. Cond. response bias7.29.821.4-4.64.34.0-4.13.5-3.5-3.2-3.2-3.2-4.13.3-2.93.3-3.33.13.13.52.7-1.8-1.9-3.2-2.6-1.51.61.0-0.9
Time in closed arm before self-admin0.91.01.7-0.60.70.8-0.71.1-1.0-1.2-1.2-1.0-0.41.1-1.11.1-1.11.11.00.71.2-1.2-1.1-0.6-0.8-1.31.2-1.1-0.6
Time in closed arm after self-admin2.32.34.3-1.41.41.8-1.21.7-1.8-1.8-1.8-1.8-0.61.5-1.61.5-1.51.61.40.81.6-2.1-1.3-0.5-2.0-2.02.0-0.7-0.0
Time in open arm before self-admin1.11.21.71.1-1.1-1.01.2-1.11.21.11.11.21.3-1.21.3-1.11.1-1.3-1.2-1.3-1.00.71.21.20.60.8-0.60.71.1
Time in open arm after self-admin1.01.12.00.8-0.9-1.00.7-1.11.11.11.11.10.4-1.21.2-1.11.1-1.1-1.0-0.6-1.21.41.00.41.11.4-1.40.70.1
Bone: periosteal estimation0.30.62.9-1.11.00.6-1.20.6-0.5-0.4-0.4-0.4-1.70.3-0.20.3-0.30.30.61.30.20.7-0.3-1.50.40.6-0.80.6-0.9
Bone: periosteal perimeter0.20.42.4-1.31.00.9-0.90.6-0.3-0.5-0.5-0.5-0.90.3-0.50.3-0.30.40.20.5-0.20.20.1-0.3-0.9-0.0-0.21.60.4
Bone: post-yield work0.20.20.6-0.30.40.6-0.30.5-0.6-0.6-0.6-0.6-0.10.3-0.30.3-0.30.60.40.20.4-0.7-0.50.0-0.7-0.70.6-0.5-0.3
Progressive ratio test 1 active lever presses0.10.10.80.2-0.10.0-0.0-0.1-0.10.10.1-0.20.00.2-0.10.1-0.10.10.20.20.3-0.3-0.4-0.10.0-0.30.2-0.9-0.6
Progressive ratio test 1 breakpoint0.10.11.20.3-0.2-0.10.0-0.0-0.10.00.0-0.20.00.0-0.10.00.0-0.00.20.20.3-0.2-0.5-0.20.2-0.20.2-1.1-0.8
Progressive ratio test 1 inactive lever presses0.10.10.40.00.0-0.1-0.10.4-0.0-0.5-0.50.0-0.30.1-0.10.1-0.10.10.20.40.20.2-0.3-0.50.6-0.0-0.2-0.5-0.6
Progressive ratio test 2 active lever presses0.80.93.3-0.91.00.5-1.30.4-0.6-0.2-0.2-0.6-1.81.0-0.80.8-0.80.81.01.60.60.3-1.0-1.70.50.1-0.4-0.6-1.8
Progressive ratio test 2 breakpoint0.50.62.7-0.60.70.2-1.00.1-0.30.10.1-0.4-1.50.7-0.60.6-0.60.60.81.40.40.4-0.8-1.50.60.3-0.6-0.5-1.7
Progressive ratio test 2 inactive lever presses0.50.52.1-0.60.70.4-0.90.5-0.5-0.4-0.4-0.5-1.20.8-0.70.6-0.60.60.81.20.60.0-0.8-1.30.4-0.2-0.1-0.7-1.4
Incentive Sensitization - Responses0.70.72.9-1.00.90.4-1.30.4-0.4-0.2-0.2-0.4-1.70.9-0.70.7-0.80.80.81.40.30.5-0.6-1.50.50.3-0.6-0.0-1.4
Incentive Sensitization - Breakpoint0.70.72.8-0.90.90.4-1.20.5-0.4-0.3-0.3-0.4-1.70.9-0.70.8-0.80.80.91.50.40.5-0.7-1.50.40.3-0.5-0.1-1.5
Sum of active levers in priming session hrs 5-60.50.50.80.7-0.7-0.70.7-0.90.80.90.90.90.7-0.60.8-0.60.5-0.6-0.8-0.8-0.80.50.90.80.30.7-0.50.50.6
Progressive ratio2.22.65.7-1.71.71.8-1.52.2-1.7-2.4-2.4-1.8-1.21.5-1.81.6-1.51.51.51.31.6-1.6-1.3-1.1-1.5-1.51.5-0.3-0.2
Food seeking constrained by brief footshock0.40.52.8-0.1-0.1-0.20.2-0.10.60.10.10.6-0.1-0.70.7-0.60.6-0.7-0.6-0.3-0.61.00.9-0.00.61.0-1.01.71.1
Seeking ratio, punishment vs. effort3.23.96.71.8-1.9-2.31.6-2.42.22.62.62.40.9-1.92.2-2.01.9-1.9-1.8-1.2-2.02.61.70.72.52.5-2.40.90.3
Retroperitoneal fat weight7.825.834.74.3-4.6-5.04.5-5.75.45.95.95.53.7-5.45.5-5.35.3-5.4-5.3-4.5-5.95.75.64.14.05.4-5.14.53.3
Reaction time number correct0.20.21.10.3-0.30.10.50.10.0-0.2-0.2-0.00.9-0.0-0.2-0.00.0-0.2-0.2-0.70.2-0.80.10.8-0.6-0.70.80.01.0
Reaction time mean minus median0.10.21.4-0.30.10.2-0.0-0.10.20.20.20.1-0.0-0.40.5-0.30.4-0.5-0.4-0.2-0.50.50.60.2-0.20.3-0.51.20.7
Reaction time mean minus median AUC0.10.10.5-0.50.30.5-0.20.4-0.2-0.3-0.3-0.3-0.1-0.10.1-0.00.0-0.1-0.0-0.1-0.1-0.00.20.2-0.6-0.10.00.70.4
Reaction time num false alarms0.60.81.30.9-1.0-0.91.0-0.91.00.90.91.11.0-1.01.1-1.01.0-0.9-1.0-1.0-1.00.81.00.90.70.9-0.70.60.7
Reaction time num false alarms AUC0.00.10.10.4-0.3-0.30.3-0.10.30.10.10.30.3-0.30.3-0.30.3-0.1-0.3-0.3-0.20.10.10.20.30.2-0.2-0.1-0.0
Reaction time trials correct on left0.20.21.10.3-0.30.10.50.10.0-0.2-0.2-0.00.9-0.0-0.2-0.00.0-0.2-0.2-0.70.2-0.80.10.8-0.6-0.70.80.01.0
Reaction time trials on left0.20.21.10.3-0.30.10.50.10.0-0.2-0.2-0.00.9-0.0-0.2-0.00.0-0.2-0.2-0.70.2-0.80.10.8-0.6-0.70.80.01.0
Reaction time mean0.50.71.30.8-0.8-0.90.8-1.01.01.01.01.00.6-0.81.0-0.80.7-1.0-0.8-0.7-0.71.01.00.51.10.9-0.70.40.5
Reaction time mean AUC0.30.40.70.6-0.6-0.70.6-0.70.70.70.70.80.5-0.50.7-0.50.5-0.7-0.6-0.5-0.50.60.80.40.80.6-0.40.20.4
Median of all reaction times0.30.51.60.8-0.8-0.90.7-0.80.80.80.80.90.5-0.50.8-0.50.5-0.7-0.5-0.4-0.30.70.60.21.30.7-0.5-0.20.1
Reaction time omissions0.10.21.2-0.1-0.0-0.10.1-0.10.30.10.10.6-0.1-0.20.3-0.30.2-0.3-0.4-0.2-0.40.80.90.10.50.7-0.51.10.7
Reaction time false alarm rate0.10.10.40.2-0.2-0.30.0-0.20.20.20.20.4-0.2-0.20.4-0.20.2-0.0-0.10.2-0.20.50.1-0.20.70.5-0.5-0.3-0.7
Reaction time premature initiation rate2.63.57.61.1-1.3-1.81.2-2.11.92.32.32.00.5-1.92.0-1.81.8-2.0-1.8-1.0-2.12.82.00.62.12.7-2.52.00.9
Reaction time premature initiations1.62.23.91.0-1.2-1.41.1-1.61.61.81.81.60.7-1.51.5-1.51.4-1.7-1.5-1.1-1.61.91.70.71.52.0-1.81.71.1
Std. dev. reaction times0.50.72.30.2-0.4-0.50.4-0.70.80.80.80.80.2-0.90.9-0.80.8-0.9-0.8-0.5-1.01.21.10.30.71.1-1.11.50.9
Reaction time trials completed0.20.21.10.3-0.30.10.50.10.0-0.2-0.2-0.00.9-0.0-0.2-0.00.0-0.2-0.2-0.70.2-0.80.10.8-0.6-0.70.80.01.0
Reaction time trials AUC0.20.21.30.4-0.4-0.10.6-0.10.20.00.00.20.9-0.20.0-0.20.2-0.4-0.3-0.80.0-0.60.30.8-0.4-0.40.60.21.2
Run reversals in cocaine runway, females2.12.16.50.6-0.8-1.00.9-1.01.41.01.01.50.5-1.41.2-1.51.5-1.5-1.5-1.0-1.82.11.80.71.12.1-2.02.61.6
Run reversals in cocaine runway, males2.52.44.6-1.81.81.9-1.51.8-1.6-1.8-1.8-1.6-1.11.8-1.81.8-1.81.81.41.11.4-1.6-1.0-0.6-2.1-1.61.60.10.0
Latency to leave start box in cocaine runway1.51.63.71.7-1.6-1.71.4-1.41.41.41.41.31.1-1.21.2-1.41.4-1.3-1.1-0.9-0.81.10.70.51.91.4-1.0-0.50.1
Latency to leave start box in cocaine runway, F1.61.86.51.6-1.5-1.81.2-1.51.41.51.51.40.6-1.21.2-1.41.4-1.4-1.0-0.5-0.81.60.5-0.22.61.7-1.5-0.4-0.3
Latency to leave start box in cocaine runway, M0.20.20.80.7-0.6-0.50.6-0.20.30.10.10.30.8-0.10.1-0.20.1-0.1-0.2-0.50.0-0.4-0.00.60.1-0.10.4-0.90.0
Std. dev. time between licks in bursts1.61.94.01.2-1.3-1.51.1-1.21.71.21.21.30.6-1.71.3-1.61.7-1.4-1.5-0.9-1.62.01.10.41.61.7-2.01.40.7
Total sessions with >9 infusions1.11.22.5-0.80.90.8-1.11.0-0.9-1.0-1.0-1.0-1.31.2-1.11.0-1.01.01.21.51.2-0.6-1.5-1.60.2-0.70.4-1.3-1.6
Short access day 1 total inactive lever presses0.40.40.8-0.60.60.5-0.70.8-0.5-0.9-0.9-0.5-0.70.8-0.70.7-0.70.70.70.70.6-0.3-0.6-0.7-0.2-0.40.3-0.5-0.7
Short access day 10 total inactive lever presses1.01.12.51.2-1.2-1.11.3-1.21.11.01.01.21.4-0.90.9-0.90.9-0.9-1.2-1.4-1.20.71.21.60.30.4-0.40.50.9
Short access day 1 total infusions0.80.83.2-0.60.80.4-1.10.7-0.6-0.6-0.6-0.6-1.50.9-0.70.7-0.70.71.01.50.90.1-1.2-1.80.80.0-0.2-0.9-1.6
Short access day 10 total infusions0.91.03.4-0.80.90.6-1.21.0-0.8-1.0-1.0-0.8-1.60.8-0.80.7-0.70.71.11.60.9-0.0-1.3-1.80.5-0.0-0.2-0.9-1.6
Short access total infusions0.60.72.7-0.40.50.3-0.80.9-0.5-0.9-0.9-0.5-1.20.6-0.60.5-0.50.50.81.30.80.1-1.2-1.60.80.0-0.2-1.1-1.6
Short access day 1 locomotion3.33.64.9-1.71.81.7-1.91.9-2.0-1.8-1.8-2.0-1.92.1-2.22.1-2.22.22.12.12.1-1.6-2.2-2.0-0.9-1.51.5-1.6-1.6
Short access day 10 total locomotion0.10.10.8-0.10.20.1-0.30.7-0.4-0.9-0.9-0.3-0.4-0.0-0.10.2-0.10.10.30.40.20.0-0.5-0.50.10.1-0.1-0.3-0.6
Short access total locomotion0.40.42.50.4-0.2-0.3-0.10.6-0.2-0.9-0.9-0.2-0.30.0-0.20.1-0.10.10.40.60.5-0.0-1.0-0.80.9-0.0-0.1-1.6-1.5
One hour access (0.3 mA shock)0.80.93.3-1.01.00.5-1.30.3-0.70.10.1-0.7-1.80.8-0.90.9-0.90.91.01.60.70.3-1.0-1.80.50.1-0.4-0.3-1.5
Compulsive drug intake0.10.10.50.3-0.2-0.40.1-0.00.2-0.1-0.10.2-0.0-0.10.2-0.10.1-0.1-0.00.10.00.2-0.2-0.30.70.2-0.2-0.4-0.3
One hour access (shock baseline)0.60.81.8-1.01.10.8-1.20.4-0.9-0.1-0.1-0.9-1.40.9-1.00.9-1.01.01.01.30.7-0.2-0.9-1.2-0.3-0.40.2-0.3-1.1
Social response proportion2.32.54.02.0-1.9-1.91.8-1.81.71.81.81.71.6-1.71.7-1.71.7-1.7-1.6-1.5-1.51.41.21.31.71.5-1.20.00.5
Social responses2.83.64.81.7-1.9-1.81.9-1.82.11.81.82.11.7-2.02.0-2.12.0-1.9-2.1-2.0-2.11.92.21.81.52.0-1.71.71.7
Social time1.21.63.01.7-1.7-1.61.6-1.41.41.31.31.41.5-1.21.4-1.21.2-1.3-1.3-1.4-0.90.91.11.11.41.1-0.7-0.10.9
Soleus weight1.13.14.81.1-1.4-1.41.4-1.71.81.81.81.81.1-2.02.0-1.92.0-2.0-1.9-1.5-2.22.12.11.41.21.9-2.02.21.5
Bone: stiffness0.10.10.4-0.30.30.5-0.30.2-0.6-0.3-0.3-0.1-0.10.30.10.3-0.30.20.30.10.2-0.40.20.2-0.5-0.10.5-0.2-0.0
Tibialis anterior weight0.20.82.10.4-0.6-0.60.7-0.90.80.90.91.10.7-0.81.0-0.90.8-0.9-1.0-1.0-1.11.01.51.00.30.8-0.71.41.1
Time to tail flick, vehicle, before self-admin0.90.91.40.8-0.9-0.80.9-1.10.91.21.21.20.9-0.80.8-1.00.9-0.8-1.0-1.0-0.90.71.20.90.40.9-0.60.91.0
Time to tail flick, vehicle, after self-admin1.71.83.0-1.71.61.7-1.41.6-1.6-1.5-1.5-1.5-1.31.4-1.41.3-1.31.61.31.21.4-1.4-1.1-1.1-1.4-1.21.20.10.0
Time to tail flick, test, before self-admin0.40.40.9-0.90.90.9-0.80.7-0.8-0.7-0.7-0.7-0.90.7-0.60.7-0.70.60.60.70.5-0.4-0.5-0.7-0.6-0.30.30.2-0.2
Time to tail flick, test, after self-admin0.20.30.9-0.90.70.5-0.70.5-0.3-0.3-0.3-0.3-0.90.2-0.30.3-0.30.30.30.60.20.3-0.1-0.90.10.3-0.31.00.3
Delta time to tail flick, vehicle, before/after SA4.04.05.3-2.02.12.1-2.02.3-2.2-2.3-2.3-2.3-1.82.1-2.12.1-2.12.22.12.02.1-2.0-2.1-1.8-1.5-1.91.7-1.1-1.1
Delta time to tail flick, test, before/after SA0.10.10.20.4-0.4-0.40.4-0.40.50.30.30.30.4-0.40.4-0.30.3-0.3-0.4-0.4-0.20.30.30.30.30.2-0.10.20.5
Tibia length0.71.92.9-1.41.51.3-1.61.3-1.5-1.1-1.1-1.5-1.61.5-1.41.5-1.51.31.61.71.6-1.1-1.6-1.7-0.6-1.21.0-1.1-1.5
Ambulatory time before self-admin0.10.10.4-0.30.30.3-0.30.3-0.4-0.3-0.3-0.3-0.20.4-0.70.4-0.40.40.40.20.4-0.5-0.3-0.1-0.5-0.50.5-0.4-0.3
Ambulatory time after self-admin0.30.41.70.1-0.00.40.30.1-0.4-0.1-0.1-0.20.80.3-0.40.2-0.20.30.1-0.50.3-1.3-0.01.0-1.3-1.01.2-0.60.4
Bone: tissue strength0.40.42.20.4-0.30.10.30.0-0.4-0.2-0.2-0.20.80.3-0.20.3-0.30.10.2-0.40.4-1.2-0.20.9-0.8-0.91.3-1.5-0.4
Total heroin consumption0.10.20.6-0.40.30.3-0.2-0.5-0.20.80.8-0.2-0.00.6-0.10.5-0.50.50.2-0.00.1-0.40.00.2-0.7-0.30.40.30.4
Bone: trabecular number0.20.31.0-0.10.20.4-0.10.4-0.6-0.5-0.5-0.50.20.4-0.50.4-0.40.50.40.00.5-1.0-0.50.3-0.8-0.81.0-0.9-0.3
Bone: trabecular spacing0.20.31.4-0.40.40.2-0.60.5-0.3-0.5-0.5-0.4-0.80.5-0.40.4-0.50.40.60.80.6-0.0-0.7-1.20.5-0.1-0.1-0.4-0.7
Bone: trabecular thickness0.40.53.1-0.30.00.20.3-0.40.30.40.40.30.5-0.40.4-0.40.4-0.5-0.7-0.9-0.90.31.11.2-0.90.4-0.11.81.6
Bone: trabecular tissue density3.24.57.11.7-1.9-1.72.2-2.12.12.12.12.12.2-2.22.4-2.22.2-2.2-2.4-2.5-2.41.72.72.50.71.7-1.42.22.5
Water consumed over 24 hours0.60.71.91.1-1.1-0.81.1-0.80.90.60.60.61.4-0.90.6-0.80.9-0.7-0.9-1.2-0.80.10.61.4-0.10.1-0.10.10.8
Number of responses in last shaping day1.61.77.41.3-1.2-1.70.8-1.21.51.31.31.4-0.1-1.11.2-1.21.1-1.1-0.8-0.0-0.82.00.4-0.82.71.7-2.0-0.2-0.9