Agpat1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	Agpat1	0.03	0.02	6.2e-03	0.01	0	0	0	3.4e-02	9.8e-02	3.7e-01	2.2e-01
2	NAcc	gene expression	Agpat1	0.03	0.02	2.5e-04	0.01	0	0	0	2.4e-02	8.3e-02	5.3e-02	8.6e-02
3	BLA	gene expression	Agpat1	0.16	0.08	1.2e-07	0.16	0.12	0.12	0.15	5.1e-09	5.3e-07	5.0e-07	3.7e-08
4	OFC	gene expression	Agpat1	0.19	0.11	1.6e-03	0.13	0.07	0.08	0.08	5.1e-04	8.1e-03	6.5e-03	6.8e-03
5	PL	gene expression	Agpat1	0.1	0.05	8.2e-11	0.11	0.09	0.11	0.1	3.8e-12	1.3e-09	1.4e-11	1.9e-11
6	Brain	isoform ratio	NM_212458.1	0.03	0.02	9.3e-03	0.02	0.01	0	0.01	2.3e-03	2.7e-02	1.7e-01	3.1e-02
7	Brain	alternative TSS	NM_212458.1	0.03	0.02	2.1e-03	0.02	0.02	0.02	0.01	2.8e-03	8.5e-03	1.1e-02	2.5e-02
8	IC	gene expression	Agpat1	0.13	0.07	6.4e-04	0.09	0.05	0.04	0.06	1.7e-04	4.0e-03	6.1e-03	1.5e-03
9	Liver	gene expression	Agpat1	0.03	0.02	1.4e-03	0	0.01	0.01	0	1.5e-01	3.2e-02	4.8e-02	8.1e-02
10	Brain	gene expression	Agpat1	0.2	0.09	2.3e-15	0.11	0.13	0.13	0.13	8.7e-11	2.7e-12	4.9e-12	3.8e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	0.7	1.2	4.7	0.5	-2.2	-1.1	-0.6	-1.1	0.6	0.5	0.3	-1.8	-0.8
Area under the delay curve	0.3	0.4	1.5	-0.2	1.0	0.5	0.0	0.5	0.6	0.3	-1.2	0.4	0.0
BMI with tail	1.9	6.5	10.6	-2.6	1.7	2.5	2.2	2.4	-2.4	-2.6	3.2	2.4	3.1
BMI without tail	3.0	9.0	12.0	-3.5	2.8	3.1	3.0	2.8	-3.3	-3.3	2.6	2.9	2.7
Body weight	3.2	14.2	20.5	-3.4	4.5	3.7	3.5	3.6	-3.3	-3.3	3.3	4.5	4.2
Weight adjusted by age	1.2	1.7	4.2	-1.0	2.0	1.0	1.1	1.1	-1.0	-1.0	0.7	2.1	1.5
Bone surface	0.0	0.1	0.2	-0.0	-0.1	-0.5	0.0	-0.4	-0.0	-0.2	0.2	-0.0	-0.0
Bone volume	0.1	0.2	0.5	-0.4	-0.5	-0.2	0.3	-0.2	-0.3	-0.5	0.7	-0.3	0.0
Breakpoint value in progressive ratio session	0.3	0.3	0.7	0.7	-0.4	-0.7	-0.5	-0.8	0.4	0.2	-0.8	-0.5	-0.6
Number of licking bursts	0.6	1.0	1.8	1.3	0.0	-1.0	-0.9	-1.0	1.2	1.2	-1.3	-0.3	-0.8
Context. condit. distance diff. score	6.3	7.6	10.9	3.1	-2.4	-3.3	-3.0	-3.3	3.0	2.9	-2.0	-2.2	-2.1
Locomotion velocity, session 1	2.0	2.1	3.1	1.1	-1.2	-1.6	-1.2	-1.7	1.4	1.4	-1.7	-1.3	-1.8
Locomotion distance, session 1	1.0	1.2	2.7	1.1	-1.6	-1.1	-0.9	-1.1	1.1	1.0	-0.4	-1.5	-0.9
Locomotion velocity, session 2	0.8	1.0	1.6	1.1	-0.5	-0.8	-1.1	-0.8	1.3	1.2	-1.2	-0.7	-0.9
Locomotion distance, session 2	1.4	2.0	3.6	1.7	-1.3	-1.2	-1.8	-1.2	1.9	1.8	-0.8	-1.2	-0.7
Locomotion velocity, session 3	0.2	0.2	0.4	-0.5	0.1	0.6	0.5	0.6	-0.5	-0.5	0.1	-0.0	-0.1
Locomotion distance, session 3	1.9	2.0	3.1	1.4	-1.8	-1.2	-1.5	-1.3	1.4	1.4	-1.0	-1.8	-1.4
Stereotopy head waving bouts, day 3	0.5	0.6	2.5	-0.2	1.6	0.5	0.7	0.6	-0.2	-0.3	-0.3	1.3	0.6
Stereotopy head waving duration, day 3	0.7	0.8	2.3	-0.8	1.5	0.7	1.0	0.7	-0.8	-0.9	-0.2	1.3	0.5
Locomotion velocity, session 7	5.2	5.7	8.4	2.6	-2.9	-2.2	-2.6	-2.2	2.7	2.7	-1.4	-2.5	-1.5
Locomotion distance, session 7	5.8	7.4	11.7	2.6	-3.4	-2.6	-2.7	-2.6	2.8	2.7	-1.9	-3.2	-2.4
Stereotopy head waving bouts, day 7	0.3	0.3	1.0	-0.4	0.7	0.4	0.5	0.5	-0.3	-0.5	-1.0	0.1	-0.6
Stereotopy head waving duration, day 7	0.4	0.5	1.3	-0.7	1.1	0.8	0.7	0.9	-0.7	-0.8	-0.4	0.6	0.0
Locomotion velocity, session 8	3.0	3.7	5.4	2.3	-0.2	-2.0	-2.3	-2.0	2.2	2.3	-2.3	-0.6	-1.4
Locomotion distance, session 8	6.4	9.3	13.9	3.7	-2.7	-3.4	-3.5	-3.4	3.5	3.4	-1.8	-2.4	-1.9
Degree of sensitization distance	0.4	0.4	0.7	0.8	-0.2	-0.7	-0.6	-0.8	0.8	0.8	-0.7	-0.2	-0.3
Degree of sensitization stereotypy	0.3	0.3	1.2	0.0	-0.1	-0.2	-0.1	-0.1	0.1	-0.0	-1.1	-0.6	-1.1
Conditioned locomotion	0.6	0.7	1.5	-0.4	1.1	0.6	0.7	0.6	-0.4	-0.6	0.8	1.2	1.2
Cocaine response after cond. corrected	0.3	0.4	1.1	1.1	-0.4	-0.5	-0.4	-0.5	1.0	0.7	0.5	-0.1	0.5
Cocaine response after cond. not corrected	0.2	0.2	0.8	0.4	0.9	0.1	-0.0	0.1	0.4	0.1	0.1	0.8	0.7
Cocaine response before conditioning	2.2	2.7	7.4	-1.8	2.7	1.6	1.4	1.6	-1.6	-1.5	-0.2	2.0	0.6
Saline control response	5.8	7.7	12.7	-3.6	2.1	3.0	3.4	3.0	-3.1	-3.1	2.1	2.0	1.8
Bone: connectivity density	0.6	0.9	3.0	0.6	-1.7	-1.1	-0.8	-1.1	0.6	0.5	0.6	-1.3	-0.4
Bone: cortical apparent density	1.9	2.7	3.9	-1.4	1.2	1.9	1.8	2.0	-1.5	-1.7	1.9	1.2	1.7
Bone: cortical area	0.1	0.2	0.6	0.0	0.8	0.5	0.5	0.5	-0.1	-0.1	-0.0	0.6	0.4
Bone: cortical porosity	0.7	0.7	4.2	0.1	0.0	-0.3	0.1	-0.2	0.3	0.2	-2.0	-0.6	-1.6
Bone: cortical porosity	0.9	0.9	4.9	0.4	0.0	-0.6	-0.2	-0.6	0.6	0.6	-2.2	-0.5	-1.6
Bone: cortical thickness	0.8	1.3	2.4	-0.8	0.6	1.5	1.6	1.5	-1.0	-1.1	1.1	0.5	0.9
Bone: cortical thickness	2.2	2.6	4.6	-1.4	1.1	2.1	1.9	2.1	-1.5	-1.5	1.7	1.0	1.5
Bone: cortical tissue density	1.8	2.5	3.6	-1.4	1.2	1.8	1.7	1.9	-1.4	-1.6	1.8	1.2	1.6
Condit. Reinf. active minus inactive responses	1.2	1.3	3.3	0.8	-0.9	-0.7	-1.1	-0.7	1.3	1.1	-1.8	-1.2	-1.4
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.6	-0.4	0.3	0.8	0.4	0.8	-0.1	-0.3	-0.4	0.1	-0.0
Condit. Reinf. active responses	1.1	1.3	2.0	0.9	-1.3	-0.7	-1.2	-0.7	1.4	1.2	-1.4	-1.3	-1.1
Condit. Reinf. inactive responses	1.2	1.5	3.7	1.0	-1.9	-1.0	-1.3	-1.0	1.1	1.1	-0.4	-1.7	-0.9
Incentive salience index mean	3.4	4.2	6.5	2.1	-1.6	-1.8	-2.3	-1.8	2.5	2.4	-2.3	-1.6	-1.7
Condit. Reinf. lever presses	4.7	6.6	9.7	3.0	-2.1	-2.7	-2.9	-2.8	3.1	3.1	-1.9	-1.8	-1.5
Condit. Reinf. active minus inactive responses	0.4	0.5	1.2	-0.8	1.1	0.7	0.6	0.7	-0.9	-0.8	-0.1	0.9	0.2
Condit. Reinf. active-inactive response ratio	0.4	0.4	1.7	-0.6	1.3	0.3	0.4	0.4	-0.7	-0.6	-0.2	1.0	0.2
Condit. Reinf. active responses	0.1	0.2	0.5	-0.5	0.3	0.3	0.4	0.3	-0.7	-0.6	0.1	0.2	-0.1
Condit. Reinf. inactive responses	0.2	0.2	0.4	-0.4	-0.0	0.6	0.4	0.6	-0.6	-0.5	0.6	0.0	0.3
Condit. Reinf. lever presses	0.4	0.5	1.4	0.3	-0.8	-0.7	-0.6	-0.6	0.2	0.3	-0.7	-1.0	-1.2
Condit. Reinf. lever reinforcers received	0.1	0.1	0.2	-0.3	0.2	0.2	0.1	0.1	-0.5	-0.4	-0.3	0.0	-0.4
Conditioned reinforcement - actives	0.0	0.1	0.3	-0.5	-0.4	0.1	-0.0	-0.1	-0.3	-0.2	0.3	-0.2	0.0
Conditioned reinforcement - inactives	0.0	0.0	0.2	-0.4	-0.3	0.0	0.0	0.1	-0.2	-0.1	-0.2	-0.1	-0.1
Conditioned locomotion	0.1	0.1	0.5	0.2	-0.4	-0.3	-0.4	-0.7	0.3	0.4	-0.2	-0.2	-0.2
Patch foraging indifference point 0 sec	2.2	4.1	6.1	-2.5	1.9	2.4	2.1	2.1	-2.2	-2.1	1.6	1.6	1.6
Patch foraging indifference point AUC	0.1	0.2	0.6	-0.3	0.6	0.3	0.4	-0.0	-0.0	-0.2	-0.8	0.3	-0.3
Delay disc. indifference point, 0s delay	0.4	0.4	1.2	0.6	0.3	-0.3	-0.8	-0.2	1.0	1.1	-0.9	0.1	-0.1
Delay disc. indifference point, 16s delay	0.2	0.2	0.5	-0.6	0.3	0.6	0.4	0.7	0.1	-0.3	-0.4	0.1	0.1
Delay disc. indifference point, 2s delay	0.4	0.5	2.3	-0.2	1.0	0.0	-0.3	-0.1	0.6	0.5	-1.5	0.5	-0.3
Delay disc. indifference point, 24s delay	0.4	0.4	1.3	-0.5	1.0	0.7	0.6	0.8	0.2	-0.2	-1.1	0.5	-0.1
Delay disc. indifference point, 4s delay	0.9	0.9	2.9	-1.1	1.7	1.2	0.8	1.0	-0.5	-0.6	-0.5	1.2	0.6
Delay disc. indifference point, 8s delay	0.3	0.4	1.6	0.3	0.5	0.2	-0.2	0.3	0.9	0.8	-1.2	0.0	-0.2
Indifference point function ln k	0.5	0.9	2.1	1.2	-0.2	-0.9	-1.0	-0.5	1.1	1.0	-1.5	-0.5	-0.8
Indifference point function log k	0.5	0.9	2.1	1.2	-0.2	-0.9	-1.0	-0.5	1.1	1.0	-1.5	-0.5	-0.8
Patch foraging total patch changes 0 sec	2.3	4.3	6.4	-2.5	1.8	2.5	2.2	2.2	-2.2	-2.1	1.6	1.6	1.6
Patch foraging total patch changes 12 sec	2.1	2.7	4.4	-2.1	1.3	1.9	1.9	1.5	-1.9	-1.8	1.2	1.2	1.1
Patch foraging total patch changes 18 sec	2.2	3.4	5.3	-2.1	0.7	2.1	1.9	1.9	-1.9	-1.9	2.3	1.0	1.7
Patch foraging total patch changes 24 sec	0.3	0.5	1.1	-1.0	-0.5	1.0	0.7	0.5	-0.7	-0.6	1.0	-0.4	0.3
Patch foraging total patch changes 6 sec	2.1	3.2	6.1	-2.5	1.4	2.2	1.8	1.9	-1.9	-1.7	1.5	1.3	1.3
Patch foraging time to switch 0 sec	0.6	1.3	5.9	-0.6	0.1	0.8	0.5	1.1	-0.9	-0.7	2.4	0.7	1.7
Patch foraging water rate 0 sec	0.1	0.3	0.7	-0.5	0.8	0.6	0.5	0.5	-0.1	-0.3	-0.2	0.7	0.5
Patch foraging water rate 12 sec	0.0	0.1	0.3	0.1	-0.3	0.3	0.5	0.2	-0.3	-0.4	0.2	-0.4	-0.0
Patch foraging water rate 18 sec	0.3	0.4	0.8	-0.5	0.7	0.9	0.7	0.8	-0.6	-0.7	0.3	0.6	0.7
Patch foraging water rate 24 sec	0.3	0.4	1.0	-0.6	0.2	0.5	0.8	0.6	-0.9	-1.0	0.7	0.3	0.4
Patch foraging water rate 6 sec	0.1	0.2	0.4	-0.2	0.2	0.6	0.6	0.5	-0.3	-0.4	0.3	0.3	0.5
Seeking ratio, delayed vs. immediate footshock	1.8	2.2	3.6	-1.1	1.8	1.8	1.9	1.5	-1.8	-1.7	0.6	1.2	0.6
Distance traveled before self-admin	0.3	0.4	1.6	0.0	0.4	-0.1	0.1	-0.1	-0.4	-0.3	1.2	0.7	1.0
Distance traveled after self-admin	1.7	2.0	3.7	-1.3	1.9	1.3	1.4	1.1	-1.6	-1.5	1.1	1.7	1.3
Extensor digitorum longus weight	0.0	0.2	0.5	0.4	0.1	-0.7	-0.4	-0.6	0.3	0.4	0.1	0.3	0.1
Bone: elastic displacement	0.1	0.1	0.2	-0.0	-0.2	0.2	0.4	0.3	-0.0	0.1	-0.3	-0.5	-0.5
Bone: elastic work	0.1	0.2	0.5	-0.2	0.5	0.5	0.7	0.5	-0.1	-0.2	-0.1	0.4	0.3
Bone: endosteal estimation	0.8	1.7	6.6	-0.9	2.6	0.4	0.6	0.4	-0.9	-0.8	-0.0	2.5	1.1
Bone: endosteal perimeter	0.3	0.6	0.9	0.7	0.9	-0.9	-0.7	-0.9	0.7	0.8	-0.9	0.9	0.1
Epididymis fat weight	4.7	16.1	29.8	-4.2	1.1	4.3	4.1	4.1	-4.3	-4.4	5.5	2.2	4.2
Delta time in closed arm before/after self-admin	0.3	0.3	0.7	-0.5	0.6	0.2	0.2	0.2	-0.5	-0.4	0.8	0.8	0.8
Delta time in open arm before/after self-admin	0.1	0.1	0.5	-0.7	-0.3	0.2	0.2	0.2	-0.5	-0.3	0.3	-0.2	-0.2
Diff in mean of infusions in LGA sessions	1.9	2.3	3.4	1.7	-1.8	-1.6	-1.8	-1.3	1.5	1.8	-0.6	-1.5	-0.9
Delay discount exponential model param	0.4	0.4	1.7	0.3	-1.0	-0.5	-0.1	-0.5	-0.5	-0.2	1.3	-0.5	0.1
Extinction: sum of active levers before priming	0.8	0.9	1.6	0.7	-0.3	-1.0	-1.2	-1.3	1.1	1.1	-1.0	-0.4	-0.5
Active lever presses in extinction session 6	0.2	0.2	0.6	-0.1	-0.8	-0.3	-0.3	-0.4	0.5	0.2	-0.4	-0.5	-0.2
Bone: final force	2.7	4.3	5.6	-1.8	2.0	2.2	2.1	2.2	-1.8	-1.8	2.1	2.1	2.4
Bone: final moment	2.1	3.3	4.0	-1.7	1.7	1.8	1.9	1.9	-1.7	-1.7	1.9	1.8	2.0
Food consumed during 24 hour testing period	0.4	0.5	1.6	-0.1	1.1	0.4	0.2	0.4	-0.1	-0.1	0.7	1.2	1.3
Glucose	3.1	4.9	6.9	2.5	-0.5	-2.6	-2.6	-2.5	2.4	2.4	-2.6	-0.7	-1.7
Heart weight	1.1	1.7	4.4	-1.8	2.1	1.2	1.1	1.3	-1.1	-1.0	-0.1	1.6	0.7
Delay discount hyperbolic model param	0.4	0.4	2.0	0.4	-1.1	-0.6	-0.1	-0.5	-0.4	-0.2	1.4	-0.5	0.1
Intermittent access intake day 1-15 change	0.1	0.2	0.4	-0.6	0.5	0.5	0.4	0.5	-0.5	-0.5	0.2	0.2	0.0
Intermittent access intake escalation	0.3	0.7	1.3	-1.1	0.6	1.1	0.9	1.0	-1.0	-1.0	0.4	0.2	0.1
Intermittent access intake escalation 2	0.0	0.0	0.2	-0.0	0.2	-0.0	-0.2	-0.0	-0.0	-0.0	-0.4	-0.2	-0.4
Intermitt. access day 1 inactive lever presses	0.1	0.4	0.8	0.9	0.3	-0.8	-0.9	-0.6	0.5	0.6	-0.4	0.4	0.1
Intermitt. access day 15 inactive lever presses	0.1	0.3	0.7	-0.8	0.7	0.4	0.4	0.4	-0.5	-0.5	0.3	0.8	0.6
Intermitt. access escalation Index	1.3	1.8	2.9	1.7	-1.2	-1.5	-1.5	-1.3	1.5	1.6	-0.8	-1.1	-0.8
Intermittent access day 1 total infusions	1.5	2.5	4.3	0.8	-2.1	-1.6	-1.5	-1.8	1.3	1.6	-1.2	-1.9	-1.6
Intermittent access day 15 total infusions	0.2	0.3	0.8	-0.6	-0.9	-0.1	-0.2	-0.2	-0.1	0.2	-0.3	-0.9	-0.8
Intermittent access terminal intake (last 3 days)	0.1	0.2	0.5	-0.7	-0.6	-0.1	-0.1	-0.3	-0.2	0.0	-0.4	-0.6	-0.7
Intermittent access total infusions	0.4	0.4	1.1	-0.3	-1.1	-0.5	-0.5	-0.6	0.2	0.4	-0.6	-1.0	-0.9
Intermittent access day 1 locomotion	0.1	0.2	0.8	-0.2	-0.9	-0.3	-0.3	-0.5	0.0	0.1	0.4	-0.6	-0.2
Intermittent access day 15 total locomotion	0.5	0.9	1.4	-1.2	1.0	1.0	1.0	0.9	-0.9	-0.9	0.9	0.9	0.9
Intermittent access total locomotion	0.2	0.3	0.8	-0.9	0.1	0.6	0.6	0.5	-0.6	-0.6	0.5	0.1	0.3
Intermittent access standard deviation	1.7	3.4	4.7	-2.2	1.6	2.0	2.1	1.8	-2.0	-1.9	1.7	1.6	1.6
Left kidney weight	3.2	14.7	16.8	-3.8	4.0	4.0	3.9	4.1	-3.7	-3.8	3.2	4.1	3.8
Right kidney weight	3.0	13.7	16.3	-3.5	3.8	3.7	3.7	3.9	-3.5	-3.5	3.4	4.0	3.9
Cocaine induced anxiety	0.1	0.1	0.3	0.5	0.1	-0.4	-0.4	-0.3	0.5	0.5	-0.1	0.2	0.2
Post-drug Anxiety	0.2	0.2	0.4	-0.5	0.6	0.3	0.3	0.4	-0.4	-0.3	0.4	0.6	0.6
Baseline Anxiety	0.2	0.2	0.4	-0.5	0.6	0.5	0.5	0.6	-0.6	-0.4	0.4	0.5	0.3
Tail length	1.1	4.2	14.8	-1.7	3.8	1.8	1.7	1.6	-1.7	-1.5	-0.2	2.9	1.1
Length with tail	1.5	6.4	20.5	-1.9	4.5	2.2	2.1	2.1	-1.8	-1.6	0.6	3.8	2.3
Length without tail	2.0	6.5	14.3	-1.7	3.5	2.1	2.0	2.2	-1.7	-1.6	2.2	3.8	3.5
Times rat made contact with spout	0.3	0.3	1.0	-0.1	-0.7	0.4	-0.0	0.4	0.1	-0.0	-0.6	-1.0	-0.8
Lifetime Intake	0.3	0.3	0.8	-0.4	-0.9	-0.4	-0.4	-0.5	0.3	0.4	-0.6	-0.8	-0.8
Liver weight, left	0.4	0.7	3.0	0.1	1.7	0.2	0.0	0.2	-0.4	-0.2	0.5	1.6	1.0
Liver weight, right	0.3	0.5	2.1	0.2	1.4	-0.2	-0.6	-0.3	0.4	0.4	-0.7	1.3	0.4
Locomotor activity	0.6	1.0	3.6	-0.7	1.9	1.0	0.9	0.7	-0.9	-0.8	-0.2	1.3	0.4
Locomotor testing distance	0.3	0.5	2.1	-0.5	1.4	0.7	0.3	0.1	-0.6	-0.3	0.1	1.0	0.5
Locomotor testing rearing	0.5	1.0	2.2	-0.9	1.5	0.7	0.6	0.3	-1.0	-0.7	0.9	1.4	1.1
Locomotion in novel chamber	0.1	0.2	0.4	-0.5	0.4	0.5	0.4	0.3	-0.6	-0.3	0.5	0.2	0.3
Locomotion in novel chamber post-restriction	1.2	2.0	2.3	-1.4	1.4	1.5	1.5	1.1	-1.4	-1.4	1.4	1.4	1.5
Fecal boli incidents, locomotor time 1	0.3	0.4	1.3	-0.2	-1.1	-0.9	-0.4	-1.1	0.1	0.1	0.3	-0.6	-0.1
Change in fecal boli incidents, locomotor task	0.5	0.5	2.6	0.4	1.6	0.5	0.1	0.5	0.1	0.3	-0.2	1.1	0.5
Time >=10cm from walls, locomotor time 1	1.8	2.0	4.7	-0.3	2.0	1.1	0.8	1.2	-0.7	-1.0	1.4	2.2	2.0
Bouts of movement, locomotor time 1	0.4	0.5	1.6	1.3	-0.5	-0.6	-0.3	-0.1	0.8	0.5	-0.7	-0.7	-0.6
Total resting periods, locomotor time 1	0.4	0.4	1.5	1.2	-0.5	-0.6	-0.3	-0.3	0.7	0.5	-0.6	-0.6	-0.6
Rest time, locomotor task time 1	0.1	0.2	0.5	0.4	-0.2	-0.7	-0.3	-0.5	-0.1	0.0	-0.6	-0.2	-0.5
Distance moved, locomotor task time 1	0.4	0.6	1.3	-0.6	0.9	1.1	0.9	1.0	-0.1	-0.5	0.4	0.9	0.9
Vertical activity count, locomotor time 1	0.7	1.8	3.1	-1.2	1.4	1.7	1.4	1.8	-0.7	-0.9	1.1	1.3	1.4
Time >=10cm from walls, locomotor time 2	0.8	1.2	3.8	-0.5	2.0	1.1	0.8	1.0	-0.2	-0.0	0.4	1.8	1.3
Bouts of movement, locomotor time 2	0.1	0.1	0.4	-0.0	0.5	0.3	0.4	0.4	-0.1	-0.1	-0.6	0.1	-0.5
Total resting periods, locomotor time 2	0.2	0.3	1.4	0.4	0.3	-0.2	0.1	0.0	0.2	0.1	-1.2	-0.2	-0.9
Rest time, locomotor task time 2	0.5	0.7	2.4	1.6	-0.3	-1.2	-0.9	-0.9	0.8	0.7	-0.4	-0.1	-0.2
Distance moved, locomotor task time 2	1.0	1.1	2.3	-1.5	0.7	1.4	1.1	1.4	-0.3	-0.6	0.9	0.9	1.2
Vertical activity count, locomotor time 2	0.7	1.0	1.9	-1.4	0.9	1.3	0.9	1.2	-0.5	-0.4	0.8	1.0	1.1
Light reinforcement 1	0.6	1.5	3.2	-0.9	1.1	1.2	0.8	1.4	-0.7	-0.7	1.7	1.3	1.8
Light reinforcement 2	0.3	0.5	1.7	-0.3	0.8	0.5	0.0	0.3	-0.1	-0.1	1.0	1.0	1.3
Bone: marrow area	0.9	2.1	7.4	-1.1	2.7	0.6	0.7	0.6	-1.1	-1.0	0.2	2.6	1.3
Bone: maximum diameter	0.6	1.2	2.2	1.2	0.2	-1.1	-1.2	-1.2	1.3	1.3	-1.5	0.0	-0.7
Bone: maximum force	1.2	2.2	2.9	-1.3	1.5	1.4	1.5	1.5	-1.3	-1.3	1.5	1.6	1.7
Bone: maximum moment	0.8	1.5	1.8	-1.2	1.2	1.1	1.3	1.1	-1.1	-1.1	1.2	1.3	1.4
Mean time between licks in bursts	1.0	2.4	4.2	1.6	-0.7	-2.1	-1.4	-2.0	1.5	1.5	-1.7	-0.9	-1.5
Mean num. licks in bursts	0.6	1.0	2.0	-1.4	-0.2	1.2	0.9	1.2	-1.2	-1.2	1.0	-0.1	0.4
Cd content in liver	0.3	0.3	1.3	-0.1	-0.9	-0.3	-0.0	-0.3	0.0	-0.0	1.1	-0.2	0.7
Co content in liver	1.8	2.1	3.8	-1.3	1.1	1.4	1.4	1.5	-1.4	-1.2	2.0	1.3	1.7
Cu content in liver	0.3	0.3	1.2	0.6	-0.9	0.3	-0.1	0.3	0.4	0.1	-0.7	-1.1	-0.6
Fe content in liver	1.0	1.2	2.0	-1.4	0.4	0.9	1.1	0.9	-1.1	-1.3	1.4	0.7	1.1
K content in liver	0.8	0.8	1.5	1.2	-1.0	-0.9	-1.0	-0.9	0.8	0.8	-0.4	-1.0	-0.7
Mg content in liver	2.5	2.6	4.9	2.2	-0.9	-1.7	-1.9	-1.7	1.7	1.8	-1.3	-1.0	-1.1
Mn content in liver	2.3	2.5	4.8	2.2	-0.3	-1.6	-2.0	-1.6	2.1	1.9	-1.6	-0.2	-0.5
Na content in liver	0.1	0.1	0.4	0.0	0.0	0.4	0.3	0.4	0.0	-0.3	-0.6	-0.3	-0.3
Rb content in liver	0.3	0.3	0.6	0.3	-0.8	-0.7	-0.6	-0.7	0.2	0.5	0.7	-0.5	-0.0
Se content in liver	2.7	3.1	6.8	1.9	-0.3	-1.5	-2.1	-1.5	1.9	2.1	-2.6	-0.9	-1.8
Sr content in liver	0.1	0.1	0.2	-0.4	-0.1	-0.4	0.3	-0.4	-0.2	-0.3	0.0	0.4	0.3
Zn content in liver	0.2	0.2	0.5	0.7	-0.2	-0.6	-0.7	-0.6	0.4	0.6	-0.1	-0.1	-0.1
Bone: minimum diameter	0.3	0.5	1.1	0.8	1.1	-0.4	-0.5	-0.4	0.7	0.7	-0.5	1.0	0.3
Time in familiar zone, hab. session 1	0.7	0.7	3.2	0.1	-1.8	-0.2	-0.1	-0.3	-0.1	0.1	-0.0	-1.6	-1.1
Time in novel zone, hab. session 1	0.9	0.9	3.3	-0.7	1.8	0.5	0.6	0.5	-0.4	-0.5	0.3	1.7	1.0
Total zone transitions, hab. session 1	0.4	0.6	0.8	0.9	-0.9	-0.8	-0.7	-0.8	0.6	0.7	-0.3	-0.8	-0.7
Total locomotion distance, hab. session 1	0.4	0.6	1.1	0.9	-1.1	-0.9	-0.8	-0.9	0.7	0.7	-0.2	-0.9	-0.6
Locomotion velocity, hab. session 1	0.3	0.4	0.6	0.7	-0.8	-0.7	-0.6	-0.7	0.5	0.4	-0.2	-0.7	-0.5
Time in familiar zone, hab. session 2	0.6	0.6	1.3	-0.5	0.2	0.9	1.0	0.9	-1.1	-1.0	1.0	0.2	0.4
Time in novel zone, hab. session 2	0.1	0.1	0.2	-0.5	0.2	-0.1	-0.1	-0.1	0.2	0.2	-0.4	0.2	-0.1
Total zone transitions, hab. session 2	0.1	0.1	0.5	0.5	-0.2	-0.0	-0.2	-0.1	0.1	0.1	0.7	-0.0	0.4
Total locomotion distance, hab. session 2	0.5	0.7	1.5	1.1	-1.2	-0.9	-1.0	-0.9	0.8	0.7	0.4	-0.9	-0.1
Locomotion velocity, hab. session 2	1.0	1.4	2.4	1.5	-1.4	-1.3	-1.4	-1.2	1.3	1.1	-0.1	-1.1	-0.5
Novel to familiar place preference ratio	0.2	0.2	0.5	0.3	-0.4	-0.5	-0.2	-0.4	0.4	0.3	-0.7	-0.5	-0.6
Novelty place preference	0.2	0.2	0.6	0.1	-0.2	-0.4	-0.2	-0.3	0.3	0.2	-0.8	-0.4	-0.7
Time in novel zone, NPP test	0.1	0.1	0.6	-0.1	-0.0	-0.3	-0.0	-0.2	0.2	0.1	-0.7	-0.3	-0.6
Total zone transitions, NPP test	1.6	2.3	3.4	1.5	-1.8	-1.8	-1.7	-1.8	1.4	1.4	-0.3	-1.6	-1.1
Total locomotion distance, NPP test	1.4	1.9	3.9	1.2	-2.0	-1.6	-1.6	-1.6	1.3	1.3	0.0	-1.4	-0.5
Locomotion velocity, NPP test	2.0	2.8	5.5	1.6	-2.3	-2.0	-2.0	-1.9	1.7	1.6	-0.1	-1.8	-0.7
Intraocular pressure	0.2	0.3	1.4	-0.4	-0.8	0.1	0.6	0.0	-0.3	-0.2	1.2	-0.5	0.1
Delta distance traveled before/after self-admin	1.3	1.4	2.8	-1.5	1.7	1.3	1.3	1.2	-1.2	-1.2	-0.4	1.0	0.1
Delta ambulatory time before/after self-admin	0.9	1.2	3.0	-1.1	1.7	1.3	1.1	1.2	-1.0	-1.0	-0.4	1.0	0.2
Parametrial fat weight	2.1	5.0	10.3	-2.1	1.3	2.2	1.9	2.3	-2.0	-2.0	3.2	1.9	2.9
Pavlov. Cond. lever latency	7.3	9.2	11.3	-3.1	2.3	3.4	3.1	3.4	-3.1	-3.1	3.2	2.5	3.0
Pavlov. Cond. magazine entry latency	3.2	4.2	7.9	2.2	-1.1	-1.8	-2.0	-1.9	2.0	2.2	-2.8	-1.6	-2.4
Pavlov. Cond. change in total contacts	1.7	1.8	4.1	1.4	-0.5	-1.1	-1.3	-1.1	1.4	1.4	-2.0	-0.9	-1.6
Pavlov. Cond. index score	6.0	7.6	10.2	3.1	-1.8	-2.7	-2.8	-2.8	2.9	3.0	-3.2	-2.1	-2.7
Pavlov. Cond. latency score	6.2	7.9	10.5	3.1	-1.8	-2.8	-2.8	-2.9	3.0	3.0	-3.2	-2.2	-2.8
Pavlov. Cond. lever contacts	6.2	7.4	9.2	3.0	-2.0	-3.0	-2.9	-3.0	3.0	3.0	-2.6	-2.0	-2.3
Pavlov. Cond. magazine entry number	2.3	2.9	5.0	-1.9	1.1	1.6	1.6	1.6	-1.7	-1.8	2.2	1.4	2.0
Pavlov. Cond. intertrial magazine entries	0.6	0.7	2.2	-1.2	-0.5	0.7	0.7	0.6	-0.7	-0.8	1.5	-0.1	0.8
Pavlov. Cond. lever-magazine prob. diff.	6.1	7.6	10.1	3.1	-1.8	-2.7	-2.9	-2.7	2.9	3.0	-3.2	-2.1	-2.7
Pavlov. Cond. response bias	4.3	5.3	7.4	2.6	-1.5	-2.2	-2.4	-2.3	2.5	2.5	-2.7	-1.7	-2.3
Pavlov. Cond. lever latency	0.1	0.1	0.4	0.2	0.5	-0.1	0.0	-0.1	0.3	0.2	0.2	0.6	0.6
Pavlov. Cond. magazine entry latency	0.4	0.5	0.9	0.5	-0.6	-0.8	-0.9	-0.9	0.5	0.7	-0.6	-0.6	-0.7
Pavlov. Cond. change in total contacts	0.1	0.1	0.4	-0.4	-0.1	0.1	0.2	0.1	-0.5	-0.4	-0.3	-0.3	-0.6
Pavlov. Cond. index score	0.1	0.2	0.6	0.1	-0.5	-0.3	-0.4	-0.4	0.1	0.1	-0.6	-0.6	-0.8
Pavlov. Cond. latency score	0.1	0.1	0.3	-0.1	-0.3	-0.1	-0.3	-0.2	-0.2	-0.1	-0.4	-0.4	-0.6
Pavlov. Cond. lever contacts	0.1	0.1	0.2	-0.2	-0.4	0.2	0.1	0.2	-0.3	-0.3	-0.1	-0.5	-0.4
Pavlov. Cond. magazine entry number	0.1	0.1	0.2	-0.1	0.3	0.3	0.5	0.4	-0.1	-0.2	0.0	0.3	0.2
Pavlov. Cond. intertrial magazine entries	0.5	0.8	1.7	1.1	-0.3	-0.8	-0.7	-0.8	1.0	0.9	-1.3	-0.6	-0.9
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.4	0.1	-0.4	-0.2	-0.4	-0.3	0.1	0.1	-0.5	-0.5	-0.7
Pavlov. Cond. response bias	0.3	0.4	0.8	0.4	-0.7	-0.4	-0.6	-0.5	0.4	0.4	-0.7	-0.8	-0.9
Time in closed arm before self-admin	0.0	0.0	0.1	-0.2	0.3	-0.1	-0.1	-0.3	0.0	0.1	-0.2	0.2	-0.1
Time in closed arm after self-admin	0.1	0.1	0.2	-0.3	0.0	-0.1	-0.2	-0.3	-0.4	-0.1	0.4	0.2	0.2
Time in open arm before self-admin	0.9	1.0	2.2	1.0	-0.6	-0.8	-0.8	-0.8	0.9	0.9	-1.5	-1.1	-1.4
Time in open arm after self-admin	0.2	0.2	0.6	0.0	-0.3	-0.2	-0.2	-0.3	0.0	0.1	-0.7	-0.5	-0.8
Bone: periosteal estimation	0.7	1.6	5.2	-0.9	2.3	0.8	0.9	0.8	-0.9	-0.9	0.2	2.1	1.1
Bone: periosteal perimeter	0.2	0.4	1.3	0.5	1.1	-0.0	-0.2	-0.1	0.5	0.4	-0.9	0.9	0.1
Bone: post-yield work	0.2	0.2	0.7	0.3	0.3	-0.8	-0.6	-0.8	0.2	0.4	0.2	0.5	0.2
Progressive ratio test 1 active lever presses	0.2	0.3	0.6	0.2	-0.7	-0.5	-0.5	-0.7	0.5	0.5	-0.4	-0.5	-0.5
Progressive ratio test 1 breakpoint	0.2	0.3	0.5	0.2	-0.6	-0.5	-0.5	-0.7	0.5	0.5	-0.4	-0.5	-0.5
Progressive ratio test 1 inactive lever presses	0.2	0.2	1.0	-0.4	-0.4	0.2	0.3	0.2	-0.4	-0.5	1.0	-0.0	0.5
Progressive ratio test 2 active lever presses	0.4	0.4	1.2	0.2	-1.1	-0.5	-0.6	-0.6	0.4	0.5	-0.4	-1.0	-0.7
Progressive ratio test 2 breakpoint	0.4	0.4	1.2	0.1	-1.1	-0.5	-0.6	-0.6	0.4	0.4	-0.4	-1.1	-0.8
Progressive ratio test 2 inactive lever presses	0.7	1.1	1.9	0.3	-1.0	-1.3	-1.4	-1.2	1.0	1.3	-0.9	-0.8	-0.9
Incentive Sensitization - Responses	0.3	0.4	0.9	0.4	-0.8	-0.6	-0.6	-0.6	0.4	0.4	-0.6	-1.0	-0.9
Incentive Sensitization - Breakpoint	0.3	0.4	1.0	0.3	-0.9	-0.5	-0.6	-0.6	0.3	0.3	-0.4	-1.0	-0.8
Sum of active levers in priming session hrs 5-6	0.5	0.4	1.2	0.4	-0.3	-0.7	-0.7	-0.6	0.6	0.4	-1.1	-0.5	-0.8
Progressive ratio	6.2	9.8	12.0	-2.7	2.9	3.4	3.4	3.4	-3.5	-3.4	2.8	2.9	2.7
Food seeking constrained by brief footshock	0.1	0.1	0.7	-0.9	-0.0	0.2	0.1	0.2	-0.3	-0.3	-0.1	-0.1	-0.1
Seeking ratio, punishment vs. effort	4.4	6.3	7.5	2.1	-2.1	-2.7	-2.7	-2.7	2.7	2.5	-2.6	-2.4	-2.5
Retroperitoneal fat weight	0.1	0.4	1.4	-0.6	-0.0	0.5	0.1	0.4	-0.3	-0.4	1.2	0.4	1.1
Reaction time number correct	1.4	2.6	4.0	-1.9	0.7	1.6	2.0	1.6	-1.8	-2.0	1.6	1.1	1.3
Reaction time mean minus median	1.4	3.5	5.3	2.0	-1.5	-2.1	-1.9	-2.3	1.9	2.0	-1.7	-1.5	-1.7
Reaction time mean minus median AUC	2.0	5.0	7.0	2.3	-2.1	-2.5	-2.3	-2.7	2.3	2.3	-1.9	-2.0	-2.0
Reaction time num false alarms	0.1	0.2	0.9	0.6	0.4	-0.1	-0.1	0.0	0.5	0.3	-0.9	0.0	-0.4
Reaction time num false alarms AUC	0.2	0.3	1.3	0.5	0.8	0.2	0.1	0.3	0.4	0.0	-1.1	0.3	-0.4
Reaction time trials correct on left	1.4	2.6	4.0	-1.9	0.7	1.6	2.0	1.6	-1.8	-2.0	1.6	1.1	1.3
Reaction time trials on left	1.3	2.5	3.9	-1.9	0.7	1.5	2.0	1.6	-1.8	-1.9	1.6	1.0	1.3
Reaction time mean	2.5	3.9	6.3	2.4	-1.3	-2.2	-2.2	-2.3	2.3	2.5	-1.4	-1.2	-1.2
Reaction time mean AUC	2.4	3.8	6.2	2.3	-1.3	-2.2	-2.2	-2.2	2.3	2.5	-1.4	-1.3	-1.2
Median of all reaction times	1.7	2.4	4.4	1.9	-0.9	-1.7	-1.8	-1.8	1.9	2.1	-0.9	-0.8	-0.7
Reaction time omissions	1.2	1.8	3.3	1.6	-1.0	-1.6	-1.4	-1.8	1.5	1.6	-0.9	-0.8	-0.9
Reaction time false alarm rate	1.0	1.4	4.4	1.5	0.3	-0.9	-1.1	-0.8	1.4	1.2	-2.1	-0.4	-1.2
Reaction time premature initiation rate	0.2	0.3	0.6	-0.8	0.5	0.4	0.3	-0.0	-0.6	-0.6	0.8	0.7	0.7
Reaction time premature initiations	1.3	2.3	3.5	-1.9	1.1	1.4	1.6	1.0	-1.7	-1.7	1.7	1.4	1.5
Std. dev. reaction times	2.2	4.1	5.4	2.3	-1.2	-2.2	-2.1	-2.3	2.1	2.3	-2.2	-1.4	-1.8
Reaction time trials completed	1.3	2.5	3.9	-1.9	0.7	1.5	2.0	1.6	-1.8	-1.9	1.6	1.0	1.3
Reaction time trials AUC	1.3	2.4	3.7	-1.8	0.6	1.5	1.9	1.5	-1.7	-1.9	1.7	1.0	1.4
Run reversals in cocaine runway, females	0.2	0.2	0.7	-0.4	-0.4	0.3	0.3	0.5	-0.6	-0.5	0.8	0.0	0.4
Run reversals in cocaine runway, males	0.8	0.8	2.2	0.7	-0.5	-1.1	-1.1	-1.5	0.8	0.8	-0.7	-0.6	-0.8
Latency to leave start box in cocaine runway	1.1	1.3	2.2	1.1	-0.6	-1.3	-1.4	-1.4	1.5	1.3	-1.0	-0.6	-0.6
Latency to leave start box in cocaine runway, F	1.1	1.3	2.2	1.0	-0.9	-1.3	-1.5	-1.3	1.4	1.2	-0.9	-0.8	-0.7
Latency to leave start box in cocaine runway, M	0.1	0.1	0.2	0.3	0.4	-0.2	-0.1	-0.2	0.4	0.3	-0.2	0.3	0.3
Std. dev. time between licks in bursts	1.0	1.3	2.5	1.2	0.2	-1.6	-1.1	-1.5	1.1	1.3	-1.4	-0.0	-0.9
Total sessions with >9 infusions	0.1	0.2	0.5	-0.1	-0.4	-0.1	-0.1	-0.4	0.1	0.3	-0.7	-0.5	-0.7
Short access day 1 total inactive lever presses	0.8	1.1	1.7	0.9	-0.7	-1.3	-1.3	-1.1	1.0	1.2	-1.3	-0.6	-0.9
Short access day 10 total inactive lever presses	0.1	0.2	0.6	0.8	-0.2	-0.4	-0.5	-0.2	0.4	0.4	0.1	-0.2	0.0
Short access day 1 total infusions	0.8	1.0	1.9	0.2	-0.9	-0.9	-1.0	-1.2	1.0	1.1	-1.4	-0.9	-1.1
Short access day 10 total infusions	0.3	0.4	1.1	-0.0	-1.0	-0.5	-0.4	-0.7	0.3	0.5	-0.3	-0.9	-0.7
Short access total infusions	0.5	0.6	1.0	-0.0	-1.0	-0.7	-0.7	-0.9	0.7	0.8	-0.9	-0.9	-0.9
Short access day 1 locomotion	0.9	1.1	1.6	1.2	-1.0	-1.1	-1.1	-1.3	1.0	1.0	-0.6	-1.1	-0.9
Short access day 10 total locomotion	0.8	1.5	5.1	-0.8	2.3	1.0	1.0	0.8	-0.9	-0.9	0.4	1.8	1.0
Short access total locomotion	0.1	0.1	0.3	0.2	0.6	-0.1	-0.1	-0.4	0.1	0.1	-0.0	0.4	0.2
One hour access (0.3 mA shock)	1.2	1.3	2.3	0.9	-1.4	-1.0	-1.1	-1.3	1.0	1.2	-0.7	-1.5	-1.2
Compulsive drug intake	1.0	1.2	3.6	1.9	-0.3	-1.3	-1.3	-1.2	1.4	1.2	-0.4	-0.3	-0.2
One hour access (shock baseline)	0.2	0.3	0.8	-0.8	-0.9	0.1	0.1	-0.1	-0.3	0.0	-0.1	-0.9	-0.6
Social response proportion	0.3	0.3	1.2	-0.1	1.1	0.2	0.2	0.3	-0.0	0.1	-0.3	1.1	0.6
Social responses	0.4	0.5	1.9	-0.4	1.4	0.6	0.4	0.6	-0.3	-0.2	-0.5	1.1	0.5
Social time	1.0	1.4	2.8	1.7	0.2	-1.3	-1.4	-1.4	1.4	1.4	-1.2	-0.2	-0.5
Soleus weight	0.5	1.5	2.5	1.6	1.3	-1.1	-1.3	-1.1	1.5	1.5	-1.0	1.1	0.1
Bone: stiffness	0.9	1.5	2.2	-1.1	1.0	1.2	1.4	1.3	-1.1	-1.1	1.5	1.1	1.4
Tibialis anterior weight	0.2	0.8	1.3	-0.7	0.5	1.1	0.9	1.2	-0.9	-1.0	1.1	0.4	0.8
Time to tail flick, vehicle, before self-admin	0.2	0.2	0.9	0.9	-0.0	0.2	0.1	0.4	0.4	0.2	0.5	-0.1	0.5
Time to tail flick, vehicle, after self-admin	0.6	0.8	1.4	0.9	-0.4	-0.9	-0.7	-0.6	1.2	1.0	-1.1	-0.6	-0.8
Time to tail flick, test, before self-admin	0.2	0.2	0.6	-0.3	0.1	0.6	0.7	0.2	-0.4	-0.5	0.1	-0.2	-0.2
Time to tail flick, test, after self-admin	1.5	1.6	3.3	0.8	-1.8	-1.1	-1.1	-1.0	0.8	0.9	-1.0	-1.8	-1.6
Delta time to tail flick, vehicle, before/after SA	1.4	1.3	2.0	0.3	-1.4	-1.1	-0.9	-1.0	1.1	1.0	-1.4	-1.4	-1.4
Delta time to tail flick, test, before/after SA	0.5	0.6	1.6	0.7	-1.3	-0.9	-1.0	-0.5	0.5	0.6	0.1	-0.9	-0.3
Tibia length	1.0	2.7	6.8	-1.6	2.6	1.0	1.1	1.0	-1.5	-1.2	1.4	2.6	1.6
Ambulatory time before self-admin	0.1	0.1	0.4	0.1	-0.2	-0.4	-0.2	-0.5	-0.1	-0.1	0.6	0.0	0.3
Ambulatory time after self-admin	0.9	1.1	2.4	-1.2	1.6	0.9	0.9	0.7	-1.1	-1.1	0.6	1.3	0.8
Bone: tissue strength	0.1	0.1	0.3	-0.5	0.2	0.0	0.2	0.1	-0.3	-0.2	0.6	0.3	0.5
Total heroin consumption	0.0	0.0	0.1	0.3	0.1	-0.1	-0.2	-0.1	0.1	-0.1	-0.3	0.1	-0.1
Bone: trabecular number	1.0	1.7	6.6	0.6	-2.6	-1.2	-0.8	-1.2	0.8	0.6	0.3	-2.1	-0.9
Bone: trabecular spacing	1.6	2.1	7.0	-0.8	2.7	1.4	1.0	1.5	-0.9	-0.8	0.1	2.2	1.2
Bone: trabecular thickness	0.5	0.6	2.7	0.1	-1.6	-0.7	-0.4	-0.6	0.3	0.3	0.6	-1.3	-0.3
Bone: trabecular tissue density	0.2	0.3	0.6	-0.8	0.3	-0.1	0.6	0.0	-0.5	-0.6	-0.7	-0.1	-0.7
Water consumed over 24 hours	0.1	0.1	0.4	0.5	0.3	-0.1	-0.4	-0.2	0.5	0.5	-0.6	0.1	-0.1
Number of responses in last shaping day	0.5	0.5	2.4	0.1	1.1	-0.5	-0.4	-0.6	0.6	0.4	-1.6	0.5	-0.5