Agpat1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Agpat1 0.03 0.02 6.2e-03 0.01 0 0 0 3.4e-02 9.8e-02 3.7e-01 2.6e-01
2 NAcc gene expression Agpat1 0.03 0.02 2.5e-04 0.01 0 0 0 2.4e-02 8.3e-02 5.3e-02 8.3e-02
3 BLA gene expression Agpat1 0.16 0.08 1.2e-07 0.16 0.12 0.12 0.15 5.1e-09 5.3e-07 5.0e-07 3.5e-08
4 OFC gene expression Agpat1 0.19 0.11 1.6e-03 0.13 0.07 0.08 0.08 5.1e-04 8.1e-03 6.5e-03 6.8e-03
5 PL gene expression Agpat1 0.1 0.05 8.2e-11 0.11 0.09 0.11 0.1 3.8e-12 1.3e-09 1.4e-11 1.8e-11
6 Brain isoform ratio NM_212458.1 0.03 0.02 9.3e-03 0.02 0.01 0 0.01 2.3e-03 2.7e-02 1.7e-01 3.0e-02
7 Brain alternative TSS NM_212458.1 0.03 0.02 2.1e-03 0.02 0.02 0.02 0.01 2.8e-03 8.5e-03 1.1e-02 2.5e-02
8 IC gene expression Agpat1 0.13 0.07 6.4e-04 0.09 0.05 0.04 0.06 1.7e-04 4.0e-03 6.1e-03 1.5e-03
9 Liver gene expression Agpat1 0.03 0.02 1.4e-03 0 0.01 0.01 0 1.5e-01 3.2e-02 4.8e-02 8.5e-02
10 Brain gene expression Agpat1 0.2 0.09 2.3e-15 0.11 0.13 0.13 0.13 8.7e-11 2.7e-12 4.9e-12 3.9e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.71.24.7-0.52.21.10.61.1-0.6-0.5-0.3-1.8-0.8
Area under the delay curve0.20.41.50.2-1.0-0.5-0.0-0.5-0.6-0.31.20.40.0
BMI with tail1.96.510.62.6-1.7-2.5-2.2-2.42.42.6-3.22.43.1
BMI without tail1.79.012.03.5-2.8-3.1-3.0-2.83.33.3-2.62.92.7
Body weight3.214.220.53.4-4.5-3.7-3.5-3.63.33.3-3.34.54.2
Weight adjusted by age0.61.74.21.0-2.0-1.0-1.1-1.11.01.0-0.72.11.5
Bone surface0.00.10.20.00.10.5-0.00.40.00.2-0.2-0.0-0.0
Bone volume0.10.20.50.40.50.2-0.30.20.30.5-0.7-0.30.0
Breakpoint value in progressive ratio session0.20.30.7-0.70.40.70.50.8-0.4-0.20.8-0.5-0.6
Number of licking bursts0.31.01.8-1.3-0.01.00.91.0-1.2-1.21.3-0.3-0.8
Context. condit. distance diff. score6.37.610.9-3.12.43.33.03.3-3.0-2.92.0-2.2-2.1
Locomotion velocity, session 11.92.13.1-1.11.21.61.21.7-1.4-1.41.7-1.3-1.8
Locomotion distance, session 11.01.22.7-1.11.61.10.91.1-1.1-1.00.4-1.5-0.9
Locomotion velocity, session 20.81.01.6-1.10.50.81.10.8-1.3-1.21.2-0.7-0.9
Locomotion distance, session 21.42.03.6-1.71.31.21.81.2-1.9-1.80.8-1.2-0.7
Locomotion velocity, session 30.20.20.40.5-0.1-0.6-0.5-0.60.50.5-0.1-0.0-0.1
Locomotion distance, session 31.82.03.1-1.41.81.21.51.3-1.4-1.41.0-1.8-1.4
Stereotopy head waving bouts, day 30.50.62.50.2-1.6-0.5-0.7-0.60.20.30.31.30.6
Stereotopy head waving duration, day 30.70.82.30.8-1.5-0.7-1.0-0.70.80.90.21.30.5
Locomotion velocity, session 75.25.78.4-2.62.92.22.62.2-2.7-2.71.4-2.5-1.5
Locomotion distance, session 75.87.411.7-2.63.42.62.72.6-2.8-2.71.9-3.2-2.4
Stereotopy head waving bouts, day 70.30.31.00.4-0.7-0.4-0.5-0.50.30.51.00.1-0.6
Stereotopy head waving duration, day 70.40.51.30.7-1.1-0.8-0.7-0.90.70.80.40.60.0
Locomotion velocity, session 83.03.75.4-2.30.22.02.32.0-2.2-2.32.3-0.6-1.4
Locomotion distance, session 86.49.313.9-3.72.73.43.53.4-3.5-3.41.8-2.4-1.9
Degree of sensitization distance0.40.40.7-0.80.20.70.60.8-0.8-0.80.7-0.2-0.3
Degree of sensitization stereotypy0.30.31.2-0.00.10.20.10.1-0.10.01.1-0.6-1.1
Conditioned locomotion0.60.71.50.4-1.1-0.6-0.7-0.60.40.6-0.81.21.2
Cocaine response after cond. corrected0.30.41.1-1.10.40.50.40.5-1.0-0.7-0.5-0.10.5
Cocaine response after cond. not corrected0.20.20.8-0.4-0.9-0.10.0-0.1-0.4-0.1-0.10.80.7
Cocaine response before conditioning2.22.77.41.8-2.7-1.6-1.4-1.61.61.50.22.00.6
Saline control response5.67.712.73.6-2.1-3.0-3.4-3.03.13.1-2.12.01.8
Bone: connectivity density0.60.93.0-0.61.71.10.81.1-0.6-0.5-0.6-1.3-0.4
Bone: cortical apparent density1.72.73.91.4-1.2-1.9-1.8-2.01.51.7-1.91.21.7
Bone: cortical area0.10.20.6-0.0-0.8-0.5-0.5-0.50.10.10.00.60.4
Bone: cortical porosity0.70.74.2-0.1-0.00.3-0.10.2-0.3-0.22.0-0.6-1.6
Bone: cortical porosity0.90.94.9-0.4-0.00.60.20.6-0.6-0.62.2-0.5-1.6
Bone: cortical thickness0.81.32.40.8-0.6-1.5-1.6-1.51.01.1-1.10.50.9
Bone: cortical thickness2.22.64.61.4-1.1-2.1-1.9-2.11.51.5-1.71.01.5
Bone: cortical tissue density1.62.53.61.4-1.2-1.8-1.7-1.91.41.6-1.81.21.6
Condit. Reinf. active minus inactive responses1.21.33.3-0.80.90.71.10.7-1.3-1.11.8-1.2-1.4
Condit. Reinf. active-inactive response ratio0.20.20.60.4-0.3-0.8-0.4-0.80.10.30.40.1-0.0
Condit. Reinf. active responses1.01.32.0-0.91.30.71.20.7-1.4-1.21.4-1.3-1.1
Condit. Reinf. inactive responses1.11.53.7-1.01.91.01.31.0-1.1-1.10.4-1.7-0.9
Incentive salience index mean3.34.26.5-2.11.61.82.31.8-2.5-2.42.3-1.6-1.7
Condit. Reinf. lever presses4.46.69.7-3.02.12.72.92.8-3.1-3.11.9-1.8-1.5
Condit. Reinf. active minus inactive responses0.30.51.20.8-1.1-0.7-0.6-0.70.90.80.10.90.2
Condit. Reinf. active-inactive response ratio0.30.41.70.6-1.3-0.3-0.4-0.40.70.60.21.00.2
Condit. Reinf. active responses0.10.20.50.5-0.3-0.3-0.4-0.30.70.6-0.10.2-0.1
Condit. Reinf. inactive responses0.10.20.40.40.0-0.6-0.4-0.60.60.5-0.60.00.3
Condit. Reinf. lever presses0.30.51.4-0.30.80.70.60.6-0.2-0.30.7-1.0-1.2
Condit. Reinf. lever reinforcers received0.10.10.20.3-0.2-0.2-0.1-0.10.50.40.30.0-0.4
Conditioned reinforcement - actives0.00.10.30.50.4-0.10.00.10.30.2-0.3-0.20.0
Conditioned reinforcement - inactives0.00.00.20.40.3-0.0-0.0-0.10.20.10.2-0.1-0.1
Conditioned locomotion0.10.10.5-0.20.40.30.40.7-0.3-0.40.2-0.2-0.2
Patch foraging indifference point 0 sec1.54.16.12.5-1.9-2.4-2.1-2.12.22.1-1.61.61.6
Patch foraging indifference point AUC0.10.20.60.3-0.6-0.3-0.40.00.00.20.80.3-0.3
Delay disc. indifference point, 0s delay0.40.41.2-0.6-0.30.30.80.2-1.0-1.10.90.1-0.1
Delay disc. indifference point, 16s delay0.10.20.50.6-0.3-0.6-0.4-0.7-0.10.30.40.10.1
Delay disc. indifference point, 2s delay0.40.52.30.2-1.0-0.00.30.1-0.6-0.51.50.5-0.3
Delay disc. indifference point, 24s delay0.30.41.30.5-1.0-0.7-0.6-0.8-0.20.21.10.5-0.1
Delay disc. indifference point, 4s delay0.90.92.91.1-1.7-1.2-0.8-1.00.50.60.51.20.6
Delay disc. indifference point, 8s delay0.20.41.6-0.3-0.5-0.20.2-0.3-0.9-0.81.20.0-0.2
Indifference point function ln k0.30.92.1-1.20.20.91.00.5-1.1-1.01.5-0.5-0.8
Indifference point function log k0.30.92.1-1.20.20.91.00.5-1.1-1.01.5-0.5-0.8
Patch foraging total patch changes 0 sec1.54.36.42.5-1.8-2.5-2.2-2.22.22.1-1.61.61.6
Patch foraging total patch changes 12 sec2.02.74.42.1-1.3-1.9-1.9-1.51.91.8-1.21.21.1
Patch foraging total patch changes 18 sec1.43.45.32.1-0.7-2.1-1.9-1.91.91.9-2.31.01.7
Patch foraging total patch changes 24 sec0.20.51.11.00.5-1.0-0.7-0.50.70.6-1.0-0.40.3
Patch foraging total patch changes 6 sec1.93.26.12.5-1.4-2.2-1.8-1.91.91.7-1.51.31.3
Patch foraging time to switch 0 sec0.31.35.90.6-0.1-0.8-0.5-1.10.90.7-2.40.71.7
Patch foraging water rate 0 sec0.10.30.70.5-0.8-0.6-0.5-0.50.10.30.20.70.5
Patch foraging water rate 12 sec0.00.10.3-0.10.3-0.3-0.5-0.20.30.4-0.2-0.4-0.0
Patch foraging water rate 18 sec0.20.40.80.5-0.7-0.9-0.7-0.80.60.7-0.30.60.7
Patch foraging water rate 24 sec0.30.41.00.6-0.2-0.5-0.8-0.60.91.0-0.70.30.4
Patch foraging water rate 6 sec0.10.20.40.2-0.2-0.6-0.6-0.50.30.4-0.30.30.5
Seeking ratio, delayed vs. immediate footshock1.52.23.61.1-1.8-1.8-1.9-1.51.81.7-0.61.20.6
Distance traveled before self-admin0.20.41.6-0.0-0.40.1-0.10.10.40.3-1.20.71.0
Distance traveled after self-admin1.22.03.71.3-1.9-1.3-1.4-1.11.61.5-1.11.71.3
Extensor digitorum longus weight0.00.20.5-0.4-0.10.70.40.6-0.3-0.4-0.10.30.1
Bone: elastic displacement0.10.10.20.00.2-0.2-0.4-0.30.0-0.10.3-0.5-0.5
Bone: elastic work0.10.20.50.2-0.5-0.5-0.7-0.50.10.20.10.40.3
Bone: endosteal estimation0.71.76.60.9-2.6-0.4-0.6-0.40.90.80.02.51.1
Bone: endosteal perimeter0.30.60.9-0.7-0.90.90.70.9-0.7-0.80.90.90.1
Epididymis fat weight3.216.129.84.2-1.1-4.3-4.1-4.14.34.4-5.52.24.2
Delta time in closed arm before/after self-admin0.30.30.70.5-0.6-0.2-0.2-0.20.50.4-0.80.80.8
Delta time in open arm before/after self-admin0.10.10.50.70.3-0.2-0.2-0.20.50.3-0.3-0.2-0.2
Diff in mean of infusions in LGA sessions1.32.33.4-1.71.81.61.81.3-1.5-1.80.6-1.5-0.9
Delay discount exponential model param0.30.41.7-0.31.00.50.10.50.50.2-1.3-0.50.1
Extinction: sum of active levers before priming0.60.91.6-0.70.31.01.21.3-1.1-1.11.0-0.4-0.5
Active lever presses in extinction session 60.20.20.60.10.80.30.30.4-0.5-0.20.4-0.5-0.2
Bone: final force2.64.35.61.8-2.0-2.2-2.1-2.21.81.8-2.12.12.4
Bone: final moment2.13.34.01.7-1.7-1.8-1.9-1.91.71.7-1.91.82.0
Food consumed during 24 hour testing period0.30.51.60.1-1.1-0.4-0.2-0.40.10.1-0.71.21.3
Glucose3.14.96.9-2.50.52.62.62.5-2.4-2.42.6-0.7-1.7
Heart weight1.11.74.41.8-2.1-1.2-1.1-1.31.11.00.11.60.7
Delay discount hyperbolic model param0.30.42.0-0.41.10.60.10.50.40.2-1.4-0.50.1
Intermittent access intake day 1-15 change0.00.20.40.6-0.5-0.5-0.4-0.50.50.5-0.20.20.0
Intermittent access intake escalation0.10.71.31.1-0.6-1.1-0.9-1.01.01.0-0.40.20.1
Intermittent access intake escalation 20.00.00.20.0-0.20.00.20.00.00.00.4-0.2-0.4
Intermitt. access day 1 inactive lever presses0.00.40.8-0.9-0.30.80.90.6-0.5-0.60.40.40.1
Intermitt. access day 15 inactive lever presses0.10.30.70.8-0.7-0.4-0.4-0.40.50.5-0.30.80.6
Intermitt. access escalation Index0.61.82.9-1.71.21.51.51.3-1.5-1.60.8-1.1-0.8
Intermittent access day 1 total infusions0.82.54.3-0.82.11.61.51.8-1.3-1.61.2-1.9-1.6
Intermittent access day 15 total infusions0.10.30.80.60.90.10.20.20.1-0.20.3-0.9-0.8
Intermittent access terminal intake (last 3 days)0.10.20.50.70.60.10.10.30.2-0.00.4-0.6-0.7
Intermittent access total infusions0.40.41.10.31.10.50.50.6-0.2-0.40.6-1.0-0.9
Intermittent access day 1 locomotion0.10.20.80.20.90.30.30.5-0.0-0.1-0.4-0.6-0.2
Intermittent access day 15 total locomotion0.20.91.41.2-1.0-1.0-1.0-0.90.90.9-0.90.90.9
Intermittent access total locomotion0.20.30.80.9-0.1-0.6-0.6-0.50.60.6-0.50.10.3
Intermittent access standard deviation0.73.44.72.2-1.6-2.0-2.1-1.82.01.9-1.71.61.6
Left kidney weight1.814.716.83.8-4.0-4.0-3.9-4.13.73.8-3.24.13.8
Right kidney weight2.013.716.33.5-3.8-3.7-3.7-3.93.53.5-3.44.03.9
Cocaine induced anxiety0.00.10.3-0.5-0.10.40.40.3-0.5-0.50.10.20.2
Post-drug Anxiety0.20.20.40.5-0.6-0.3-0.3-0.40.40.3-0.40.60.6
Baseline Anxiety0.10.20.40.5-0.6-0.5-0.5-0.60.60.4-0.40.50.3
Tail length0.84.214.81.7-3.8-1.8-1.7-1.61.71.50.22.91.1
Length with tail1.46.420.51.9-4.5-2.2-2.1-2.11.81.6-0.63.82.3
Length without tail1.26.514.31.7-3.5-2.1-2.0-2.21.71.6-2.23.83.5
Times rat made contact with spout0.30.31.00.10.7-0.40.0-0.4-0.10.00.6-1.0-0.8
Lifetime Intake0.30.30.80.40.90.40.40.5-0.3-0.40.6-0.8-0.8
Liver weight, left0.40.73.0-0.1-1.7-0.2-0.0-0.20.40.2-0.51.61.0
Liver weight, right0.30.52.1-0.2-1.40.20.60.3-0.4-0.40.71.30.4
Locomotor activity0.61.03.60.7-1.9-1.0-0.9-0.70.90.80.21.30.4
Locomotor testing distance0.20.52.10.5-1.4-0.7-0.3-0.10.60.3-0.11.00.5
Locomotor testing rearing0.31.02.20.9-1.5-0.7-0.6-0.31.00.7-0.91.41.1
Locomotion in novel chamber0.10.20.40.5-0.4-0.5-0.4-0.30.60.3-0.50.20.3
Locomotion in novel chamber post-restriction0.72.02.31.4-1.4-1.5-1.5-1.11.41.4-1.41.41.5
Fecal boli incidents, locomotor time 10.10.41.30.21.10.90.41.1-0.1-0.1-0.3-0.6-0.1
Change in fecal boli incidents, locomotor task0.50.52.6-0.4-1.6-0.5-0.1-0.5-0.1-0.30.21.10.5
Time >=10cm from walls, locomotor time 11.62.04.70.3-2.0-1.1-0.8-1.20.71.0-1.42.22.0
Bouts of movement, locomotor time 10.40.51.6-1.30.50.60.30.1-0.8-0.50.7-0.7-0.6
Total resting periods, locomotor time 10.40.41.5-1.20.50.60.30.3-0.7-0.50.6-0.6-0.6
Rest time, locomotor task time 10.10.20.5-0.40.20.70.30.50.1-0.00.6-0.2-0.5
Distance moved, locomotor task time 10.20.61.30.6-0.9-1.1-0.9-1.00.10.5-0.40.90.9
Vertical activity count, locomotor time 10.31.83.11.2-1.4-1.7-1.4-1.80.70.9-1.11.31.4
Time >=10cm from walls, locomotor time 20.41.23.80.5-2.0-1.1-0.8-1.00.20.0-0.41.81.3
Bouts of movement, locomotor time 20.00.10.40.0-0.5-0.3-0.4-0.40.10.10.60.1-0.5
Total resting periods, locomotor time 20.10.31.4-0.4-0.30.2-0.1-0.0-0.2-0.11.2-0.2-0.9
Rest time, locomotor task time 20.40.72.4-1.60.31.20.90.9-0.8-0.70.4-0.1-0.2
Distance moved, locomotor task time 20.91.12.31.5-0.7-1.4-1.1-1.40.30.6-0.90.91.2
Vertical activity count, locomotor time 20.41.01.91.4-0.9-1.3-0.9-1.20.50.4-0.81.01.1
Light reinforcement 10.31.53.20.9-1.1-1.2-0.8-1.40.70.7-1.71.31.8
Light reinforcement 20.20.51.70.3-0.8-0.5-0.0-0.30.10.1-1.01.01.3
Bone: marrow area0.82.17.41.1-2.7-0.6-0.7-0.61.11.0-0.22.61.3
Bone: maximum diameter0.61.22.2-1.2-0.21.11.21.2-1.3-1.31.50.0-0.7
Bone: maximum force1.12.22.91.3-1.5-1.4-1.5-1.51.31.3-1.51.61.7
Bone: maximum moment0.81.51.81.2-1.2-1.1-1.3-1.11.11.1-1.21.31.4
Mean time between licks in bursts0.42.44.2-1.60.72.11.42.0-1.5-1.51.7-0.9-1.5
Mean num. licks in bursts0.41.02.01.40.2-1.2-0.9-1.21.21.2-1.0-0.10.4
Cd content in liver0.30.31.30.10.90.30.00.3-0.00.0-1.1-0.20.7
Co content in liver1.82.13.81.3-1.1-1.4-1.4-1.51.41.2-2.01.31.7
Cu content in liver0.30.31.2-0.60.9-0.30.1-0.3-0.4-0.10.7-1.1-0.6
Fe content in liver0.91.22.01.4-0.4-0.9-1.1-0.91.11.3-1.40.71.1
K content in liver0.80.81.5-1.21.00.91.00.9-0.8-0.80.4-1.0-0.7
Mg content in liver2.32.64.9-2.20.91.71.91.7-1.7-1.81.3-1.0-1.1
Mn content in liver2.22.54.8-2.20.31.62.01.6-2.1-1.91.6-0.2-0.5
Na content in liver0.10.10.4-0.0-0.0-0.4-0.3-0.4-0.00.30.6-0.3-0.3
Rb content in liver0.30.30.6-0.30.80.70.60.7-0.2-0.5-0.7-0.5-0.0
Se content in liver2.73.16.8-1.90.31.52.11.5-1.9-2.12.6-0.9-1.8
Sr content in liver0.10.10.20.40.10.4-0.30.40.20.3-0.00.40.3
Zn content in liver0.20.20.5-0.70.20.60.70.6-0.4-0.60.1-0.1-0.1
Bone: minimum diameter0.20.51.1-0.8-1.10.40.50.4-0.7-0.70.51.00.3
Time in familiar zone, hab. session 10.60.73.2-0.11.80.20.10.30.1-0.10.0-1.6-1.1
Time in novel zone, hab. session 10.80.93.30.7-1.8-0.5-0.6-0.50.40.5-0.31.71.0
Total zone transitions, hab. session 10.40.60.8-0.90.90.80.70.8-0.6-0.70.3-0.8-0.7
Total locomotion distance, hab. session 10.40.61.1-0.91.10.90.80.9-0.7-0.70.2-0.9-0.6
Locomotion velocity, hab. session 10.30.40.6-0.70.80.70.60.7-0.5-0.40.2-0.7-0.5
Time in familiar zone, hab. session 20.60.61.30.5-0.2-0.9-1.0-0.91.11.0-1.00.20.4
Time in novel zone, hab. session 20.10.10.20.5-0.20.10.10.1-0.2-0.20.40.2-0.1
Total zone transitions, hab. session 20.10.10.5-0.50.20.00.20.1-0.1-0.1-0.7-0.00.4
Total locomotion distance, hab. session 20.50.71.5-1.11.20.91.00.9-0.8-0.7-0.4-0.9-0.1
Locomotion velocity, hab. session 21.01.42.4-1.51.41.31.41.2-1.3-1.10.1-1.1-0.5
Novel to familiar place preference ratio0.20.20.5-0.30.40.50.20.4-0.4-0.30.7-0.5-0.6
Novelty place preference0.10.20.6-0.10.20.40.20.3-0.3-0.20.8-0.4-0.7
Time in novel zone, NPP test0.10.10.60.10.00.30.00.2-0.2-0.10.7-0.3-0.6
Total zone transitions, NPP test1.52.33.4-1.51.81.81.71.8-1.4-1.40.3-1.6-1.1
Total locomotion distance, NPP test1.41.93.9-1.22.01.61.61.6-1.3-1.3-0.0-1.4-0.5
Locomotion velocity, NPP test2.02.85.5-1.62.32.02.01.9-1.7-1.60.1-1.8-0.7
Intraocular pressure0.20.31.40.40.8-0.1-0.6-0.00.30.2-1.2-0.50.1
Delta distance traveled before/after self-admin1.31.42.81.5-1.7-1.3-1.3-1.21.21.20.41.00.1
Delta ambulatory time before/after self-admin0.71.23.01.1-1.7-1.3-1.1-1.21.01.00.41.00.2
Parametrial fat weight2.15.010.32.1-1.3-2.2-1.9-2.32.02.0-3.21.92.9
Pavlov. Cond. lever latency7.39.211.33.1-2.3-3.4-3.1-3.43.13.1-3.22.53.0
Pavlov. Cond. magazine entry latency3.24.27.9-2.21.11.82.01.9-2.0-2.22.8-1.6-2.4
Pavlov. Cond. change in total contacts1.61.84.1-1.40.51.11.31.1-1.4-1.42.0-0.9-1.6
Pavlov. Cond. index score6.07.610.2-3.11.82.72.82.8-2.9-3.03.2-2.1-2.7
Pavlov. Cond. latency score6.27.910.5-3.11.82.82.82.9-3.0-3.03.2-2.2-2.8
Pavlov. Cond. lever contacts6.17.49.2-3.02.03.02.93.0-3.0-3.02.6-2.0-2.3
Pavlov. Cond. magazine entry number2.32.95.01.9-1.1-1.6-1.6-1.61.71.8-2.21.42.0
Pavlov. Cond. intertrial magazine entries0.60.72.21.20.5-0.7-0.7-0.60.70.8-1.5-0.10.8
Pavlov. Cond. lever-magazine prob. diff.6.17.610.1-3.11.82.72.92.7-2.9-3.03.2-2.1-2.7
Pavlov. Cond. response bias4.25.37.4-2.61.52.22.42.3-2.5-2.52.7-1.7-2.3
Pavlov. Cond. lever latency0.10.10.4-0.2-0.50.1-0.00.1-0.3-0.2-0.20.60.6
Pavlov. Cond. magazine entry latency0.30.50.9-0.50.60.80.90.9-0.5-0.70.6-0.6-0.7
Pavlov. Cond. change in total contacts0.10.10.40.40.1-0.1-0.2-0.10.50.40.3-0.3-0.6
Pavlov. Cond. index score0.10.20.6-0.10.50.30.40.4-0.1-0.10.6-0.6-0.8
Pavlov. Cond. latency score0.10.10.30.10.30.10.30.20.20.10.4-0.4-0.6
Pavlov. Cond. lever contacts0.10.10.20.20.4-0.2-0.1-0.20.30.30.1-0.5-0.4
Pavlov. Cond. magazine entry number0.10.10.20.1-0.3-0.3-0.5-0.40.10.2-0.00.30.2
Pavlov. Cond. intertrial magazine entries0.40.81.7-1.10.30.80.70.8-1.0-0.91.3-0.6-0.9
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.10.40.20.40.3-0.1-0.10.5-0.5-0.7
Pavlov. Cond. response bias0.30.40.8-0.40.70.40.60.5-0.4-0.40.7-0.8-0.9
Time in closed arm before self-admin0.00.00.10.2-0.30.10.10.3-0.0-0.10.20.2-0.1
Time in closed arm after self-admin0.10.10.20.3-0.00.10.20.30.40.1-0.40.20.2
Time in open arm before self-admin0.81.02.2-1.00.60.80.80.8-0.9-0.91.5-1.1-1.4
Time in open arm after self-admin0.20.20.6-0.00.30.20.20.3-0.0-0.10.7-0.5-0.8
Bone: periosteal estimation0.71.65.20.9-2.3-0.8-0.9-0.80.90.9-0.22.11.1
Bone: periosteal perimeter0.20.41.3-0.5-1.10.00.20.1-0.5-0.40.90.90.1
Bone: post-yield work0.10.20.7-0.3-0.30.80.60.8-0.2-0.4-0.20.50.2
Progressive ratio test 1 active lever presses0.20.30.6-0.20.70.50.50.7-0.5-0.50.4-0.5-0.5
Progressive ratio test 1 breakpoint0.10.30.5-0.20.60.50.50.7-0.5-0.50.4-0.5-0.5
Progressive ratio test 1 inactive lever presses0.10.21.00.40.4-0.2-0.3-0.20.40.5-1.0-0.00.5
Progressive ratio test 2 active lever presses0.30.41.2-0.21.10.50.60.6-0.4-0.50.4-1.0-0.7
Progressive ratio test 2 breakpoint0.40.41.2-0.11.10.50.60.6-0.4-0.40.4-1.1-0.8
Progressive ratio test 2 inactive lever presses0.41.11.9-0.31.01.31.41.2-1.0-1.30.9-0.8-0.9
Incentive Sensitization - Responses0.20.40.9-0.40.80.60.60.6-0.4-0.40.6-1.0-0.9
Incentive Sensitization - Breakpoint0.20.41.0-0.30.90.50.60.6-0.3-0.30.4-1.0-0.8
Sum of active levers in priming session hrs 5-60.50.41.2-0.40.30.70.70.6-0.6-0.41.1-0.5-0.8
Progressive ratio3.39.812.02.7-2.9-3.4-3.4-3.43.53.4-2.82.92.7
Food seeking constrained by brief footshock0.10.10.70.90.0-0.2-0.1-0.20.30.30.1-0.1-0.1
Seeking ratio, punishment vs. effort2.86.37.5-2.12.12.72.72.7-2.7-2.52.6-2.4-2.5
Retroperitoneal fat weight0.10.41.40.60.0-0.5-0.1-0.40.30.4-1.20.41.1
Reaction time number correct0.72.64.01.9-0.7-1.6-2.0-1.61.82.0-1.61.11.3
Reaction time mean minus median0.53.55.3-2.01.52.11.92.3-1.9-2.01.7-1.5-1.7
Reaction time mean minus median AUC0.85.07.0-2.32.12.52.32.7-2.3-2.31.9-2.0-2.0
Reaction time num false alarms0.10.20.9-0.6-0.40.10.1-0.0-0.5-0.30.90.0-0.4
Reaction time num false alarms AUC0.10.31.3-0.5-0.8-0.2-0.1-0.3-0.4-0.01.10.3-0.4
Reaction time trials correct on left0.72.64.01.9-0.7-1.6-2.0-1.61.82.0-1.61.11.3
Reaction time trials on left0.72.53.91.9-0.7-1.5-2.0-1.61.81.9-1.61.01.3
Reaction time mean1.83.96.3-2.41.32.22.22.3-2.3-2.51.4-1.2-1.2
Reaction time mean AUC1.63.86.2-2.31.32.22.22.2-2.3-2.51.4-1.3-1.2
Median of all reaction times1.52.44.4-1.90.91.71.81.8-1.9-2.10.9-0.8-0.7
Reaction time omissions1.11.83.3-1.61.01.61.41.8-1.5-1.60.9-0.8-0.9
Reaction time false alarm rate1.01.44.4-1.5-0.30.91.10.8-1.4-1.22.1-0.4-1.2
Reaction time premature initiation rate0.20.30.60.8-0.5-0.4-0.30.00.60.6-0.80.70.7
Reaction time premature initiations0.82.33.51.9-1.1-1.4-1.6-1.01.71.7-1.71.41.5
Std. dev. reaction times1.24.15.4-2.31.22.22.12.3-2.1-2.32.2-1.4-1.8
Reaction time trials completed0.72.53.91.9-0.7-1.5-2.0-1.61.81.9-1.61.01.3
Reaction time trials AUC0.72.43.71.8-0.6-1.5-1.9-1.51.71.9-1.71.01.4
Run reversals in cocaine runway, females0.20.20.70.40.4-0.3-0.3-0.50.60.5-0.80.00.4
Run reversals in cocaine runway, males0.70.82.2-0.70.51.11.11.5-0.8-0.80.7-0.6-0.8
Latency to leave start box in cocaine runway0.91.32.2-1.10.61.31.41.4-1.5-1.31.0-0.6-0.6
Latency to leave start box in cocaine runway, F1.01.32.2-1.00.91.31.51.3-1.4-1.20.9-0.8-0.7
Latency to leave start box in cocaine runway, M0.10.10.2-0.3-0.40.20.10.2-0.4-0.30.20.30.3
Std. dev. time between licks in bursts0.71.32.5-1.2-0.21.61.11.5-1.1-1.31.4-0.0-0.9
Total sessions with >9 infusions0.10.20.50.10.40.10.10.4-0.1-0.30.7-0.5-0.7
Short access day 1 total inactive lever presses0.61.11.7-0.90.71.31.31.1-1.0-1.21.3-0.6-0.9
Short access day 10 total inactive lever presses0.00.20.6-0.80.20.40.50.2-0.4-0.4-0.1-0.20.0
Short access day 1 total infusions0.51.01.9-0.20.90.91.01.2-1.0-1.11.4-0.9-1.1
Short access day 10 total infusions0.20.41.10.01.00.50.40.7-0.3-0.50.3-0.9-0.7
Short access total infusions0.40.61.00.01.00.70.70.9-0.7-0.80.9-0.9-0.9
Short access day 1 locomotion0.71.11.6-1.21.01.11.11.3-1.0-1.00.6-1.1-0.9
Short access day 10 total locomotion0.41.55.10.8-2.3-1.0-1.0-0.80.90.9-0.41.81.0
Short access total locomotion0.10.10.3-0.2-0.60.10.10.4-0.1-0.10.00.40.2
One hour access (0.3 mA shock)1.11.32.3-0.91.41.01.11.3-1.0-1.20.7-1.5-1.2
Compulsive drug intake0.81.23.6-1.90.31.31.31.2-1.4-1.20.4-0.3-0.2
One hour access (shock baseline)0.10.30.80.80.9-0.1-0.10.10.3-0.00.1-0.9-0.6
Social response proportion0.20.31.20.1-1.1-0.2-0.2-0.30.0-0.10.31.10.6
Social responses0.40.51.90.4-1.4-0.6-0.4-0.60.30.20.51.10.5
Social time0.91.42.8-1.7-0.21.31.41.4-1.4-1.41.2-0.2-0.5
Soleus weight0.51.52.5-1.6-1.31.11.31.1-1.5-1.51.01.10.1
Bone: stiffness0.81.52.21.1-1.0-1.2-1.4-1.31.11.1-1.51.11.4
Tibialis anterior weight0.20.81.30.7-0.5-1.1-0.9-1.20.91.0-1.10.40.8
Time to tail flick, vehicle, before self-admin0.10.20.9-0.90.0-0.2-0.1-0.4-0.4-0.2-0.5-0.10.5
Time to tail flick, vehicle, after self-admin0.40.81.4-0.90.40.90.70.6-1.2-1.01.1-0.6-0.8
Time to tail flick, test, before self-admin0.10.20.60.3-0.1-0.6-0.7-0.20.40.5-0.1-0.2-0.2
Time to tail flick, test, after self-admin1.51.63.3-0.81.81.11.11.0-0.8-0.91.0-1.8-1.6
Delta time to tail flick, vehicle, before/after SA1.21.32.0-0.31.41.10.91.0-1.1-1.01.4-1.4-1.4
Delta time to tail flick, test, before/after SA0.50.61.6-0.71.30.91.00.5-0.5-0.6-0.1-0.9-0.3
Tibia length1.02.76.81.6-2.6-1.0-1.1-1.01.51.2-1.42.61.6
Ambulatory time before self-admin0.00.10.4-0.10.20.40.20.50.10.1-0.60.00.3
Ambulatory time after self-admin0.71.12.41.2-1.6-0.9-0.9-0.71.11.1-0.61.30.8
Bone: tissue strength0.10.10.30.5-0.2-0.0-0.2-0.10.30.2-0.60.30.5
Total heroin consumption0.00.00.1-0.3-0.10.10.20.1-0.10.10.30.1-0.1
Bone: trabecular number0.91.76.6-0.62.61.20.81.2-0.8-0.6-0.3-2.1-0.9
Bone: trabecular spacing1.42.17.00.8-2.7-1.4-1.0-1.50.90.8-0.12.21.2
Bone: trabecular thickness0.40.62.7-0.11.60.70.40.6-0.3-0.3-0.6-1.3-0.3
Bone: trabecular tissue density0.20.30.60.8-0.30.1-0.6-0.00.50.60.7-0.1-0.7
Water consumed over 24 hours0.10.10.4-0.5-0.30.10.40.2-0.5-0.50.60.1-0.1
Number of responses in last shaping day0.40.52.4-0.1-1.10.50.40.6-0.6-0.41.60.5-0.5