Hub : Genes

Abtb2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Abtb2 0.11 0.09 1.2e-03 0.05 0.03 0.01 0.04 5.4e-03 1.4e-02 8.7e-02 6.5e-03
2 Brain gene expression Abtb2 0.2 0.12 1.1e-16 0.17 0.18 0.16 0.13 1.5e-15 8.7e-17 3.3e-15 7.2e-12
3 pVTA gene expression Abtb2 0.14 0.08 9.5e-15 0.19 0.2 0.19 0.19 4.5e-15 1.2e-15 4.1e-15 3.0e-15
4 Liver gene expression Abtb2 0.2 0.12 0.0e+00 0.18 0.19 0.18 0.18 7.6e-20 6.3e-21 5.6e-20 4.0e-20
5 BLA gene expression Abtb2 0.08 0.07 4.1e-04 0.03 0.03 0.02 0.02 1.4e-02 8.9e-03 2.0e-02 2.8e-02
6 OFC gene expression Abtb2 0.14 0.12 3.3e-03 0.09 0.1 0.09 0.1 3.4e-03 2.0e-03 4.9e-03 2.6e-03
7 LHb gene expression Abtb2 0.14 0.11 2.7e-03 0.01 0.09 0.04 0.04 1.4e-01 4.2e-03 3.3e-02 4.1e-02
8 PL gene expression Abtb2 0.04 0.03 4.9e-05 0.03 0.04 0.04 0.04 5.0e-04 2.9e-05 4.0e-05 1.8e-05
9 Eye gene expression Abtb2 0.34 0.22 2.4e-03 0.17 0.16 0.14 0.18 1.3e-03 1.8e-03 3.4e-03 1.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.81.31.6-1.1-1.2-1.11.1-1.1-1.1-1.1-1.21.3
Area under the delay curve0.00.10.20.40.10.2-0.20.20.30.20.1-0.2
BMI with tail0.10.30.50.10.50.6-0.60.60.70.70.6-0.5
BMI without tail0.00.10.3-0.5-0.0-0.20.3-0.3-0.3-0.3-0.30.2
Body weight0.20.91.8-1.3-0.7-0.90.9-1.0-1.0-0.9-0.80.8
Weight adjusted by age2.33.53.91.81.81.8-1.91.91.91.91.9-2.0
Bone surface0.71.31.7-1.1-1.2-1.11.1-1.1-1.1-1.1-1.11.3
Bone volume1.73.03.7-1.8-1.8-1.71.7-1.7-1.6-1.7-1.71.9
Breakpoint value in progressive ratio session1.62.02.51.41.61.4-1.41.31.31.41.4-1.4
Number of licking bursts0.20.30.5-0.3-0.7-0.60.6-0.6-0.5-0.6-0.70.5
Context. condit. distance diff. score3.33.94.2-1.7-2.0-2.02.0-2.0-2.0-2.0-2.02.0
Locomotion velocity, session 10.00.10.10.10.30.3-0.30.30.30.30.2-0.1
Locomotion distance, session 10.00.00.0-0.2-0.2-0.0-0.00.00.10.0-0.00.2
Locomotion velocity, session 20.00.00.10.30.10.0-0.10.00.10.0-0.10.0
Locomotion distance, session 20.20.30.5-0.7-0.6-0.50.5-0.5-0.5-0.5-0.50.7
Locomotion velocity, session 30.10.10.2-0.3-0.4-0.20.2-0.2-0.1-0.2-0.20.4
Locomotion distance, session 30.20.20.2-0.5-0.5-0.40.4-0.4-0.4-0.4-0.40.5
Stereotopy head waving bouts, day 30.00.00.10.00.10.2-0.20.20.30.30.2-0.1
Stereotopy head waving duration, day 30.30.30.5-0.5-0.6-0.60.6-0.6-0.5-0.6-0.60.7
Locomotion velocity, session 70.00.00.1-0.4-0.1-0.10.1-0.1-0.2-0.1-0.00.2
Locomotion distance, session 70.30.40.60.40.70.7-0.60.60.60.60.8-0.6
Stereotopy head waving bouts, day 70.00.00.10.1-0.1-0.10.1-0.1-0.0-0.1-0.10.3
Stereotopy head waving duration, day 70.00.00.10.1-0.1-0.10.1-0.1-0.1-0.1-0.10.3
Locomotion velocity, session 80.50.60.8-0.9-0.7-0.70.7-0.8-0.8-0.8-0.70.9
Locomotion distance, session 83.24.64.9-2.1-2.2-2.22.2-2.2-2.2-2.2-2.02.2
Degree of sensitization distance0.30.30.50.60.70.5-0.50.50.50.50.6-0.7
Degree of sensitization stereotypy0.00.00.10.1-0.1-0.00.00.00.00.0-0.00.3
Conditioned locomotion3.74.34.92.22.02.1-2.12.12.12.12.0-2.0
Cocaine response after cond. corrected2.73.23.41.61.81.8-1.81.81.81.81.8-1.9
Cocaine response after cond. not corrected0.70.80.90.80.90.9-0.90.90.90.90.9-1.0
Cocaine response before conditioning5.66.77.5-2.3-2.5-2.72.6-2.7-2.6-2.7-2.72.5
Saline control response0.81.01.1-1.0-1.0-1.01.0-1.0-1.0-1.0-1.11.0
Bone: connectivity density0.60.91.2-0.8-1.0-1.01.0-0.9-0.9-0.9-1.01.1
Bone: cortical apparent density0.00.00.1-0.20.20.1-0.00.10.00.10.30.3
Bone: cortical area0.20.30.4-0.5-0.3-0.50.6-0.6-0.7-0.6-0.50.4
Bone: cortical porosity0.10.10.20.40.30.3-0.40.30.40.30.2-0.4
Bone: cortical porosity0.20.20.30.60.40.4-0.40.40.40.40.3-0.6
Bone: cortical thickness0.00.00.0-0.00.2-0.00.0-0.1-0.1-0.10.1-0.0
Bone: cortical thickness3.64.34.72.12.12.0-2.02.02.02.02.0-2.2
Bone: cortical tissue density0.00.00.1-0.20.20.1-0.00.0-0.00.10.20.3
Condit. Reinf. active minus inactive responses1.61.82.3-1.1-1.4-1.41.4-1.3-1.3-1.4-1.51.3
Condit. Reinf. active-inactive response ratio3.23.54.0-1.6-1.9-1.91.9-1.8-1.8-1.9-2.01.9
Condit. Reinf. active responses0.60.70.9-0.6-0.9-0.90.8-0.8-0.8-0.9-1.00.8
Condit. Reinf. inactive responses0.50.60.70.70.80.7-0.70.70.70.70.9-0.7
Incentive salience index mean1.51.82.2-1.1-1.4-1.41.3-1.4-1.3-1.4-1.51.3
Condit. Reinf. lever presses0.81.11.3-0.9-1.0-1.11.1-1.1-1.1-1.1-1.21.0
Condit. Reinf. active minus inactive responses1.01.31.7-0.9-1.1-1.21.2-1.2-1.2-1.2-1.31.1
Condit. Reinf. active-inactive response ratio3.23.84.4-1.6-1.8-2.02.0-2.0-2.0-2.0-2.11.9
Condit. Reinf. active responses0.60.81.1-0.8-1.0-1.00.9-0.9-0.9-0.9-1.00.8
Condit. Reinf. inactive responses0.00.10.10.10.10.2-0.20.30.30.30.2-0.2
Condit. Reinf. lever presses0.70.91.2-0.8-1.0-1.01.0-1.0-1.0-1.0-1.10.9
Condit. Reinf. lever reinforcers received0.60.81.1-0.8-1.0-0.90.9-0.9-0.9-0.9-1.00.9
Conditioned reinforcement - actives2.74.65.2-2.2-1.9-2.22.2-2.3-2.3-2.2-2.02.0
Conditioned reinforcement - inactives6.29.19.4-3.1-3.1-3.03.0-3.0-3.0-3.0-3.02.9
Conditioned locomotion1.31.72.8-1.7-1.4-1.31.3-1.3-1.2-1.2-1.11.1
Patch foraging indifference point 0 sec0.20.30.50.30.20.5-0.60.60.70.60.5-0.6
Patch foraging indifference point AUC1.21.72.11.31.51.3-1.31.21.21.31.4-1.4
Delay disc. indifference point, 0s delay0.00.00.00.10.0-0.10.1-0.1-0.1-0.10.10.2
Delay disc. indifference point, 16s delay1.71.92.11.51.41.3-1.41.31.31.31.4-1.4
Delay disc. indifference point, 2s delay0.20.30.60.80.50.4-0.50.50.50.50.4-0.5
Delay disc. indifference point, 24s delay0.20.20.20.50.40.4-0.40.40.40.40.4-0.5
Delay disc. indifference point, 4s delay0.20.20.40.70.40.4-0.40.40.50.40.4-0.3
Delay disc. indifference point, 8s delay0.30.40.5-0.4-0.7-0.60.6-0.6-0.5-0.6-0.70.6
Indifference point function ln k0.91.61.8-1.2-1.3-1.31.2-1.2-1.2-1.2-1.31.3
Indifference point function log k0.91.61.8-1.2-1.3-1.31.2-1.2-1.2-1.2-1.31.3
Patch foraging total patch changes 0 sec0.10.20.30.20.10.4-0.40.50.50.50.3-0.5
Patch foraging total patch changes 12 sec0.00.00.1-0.3-0.1-0.10.1-0.1-0.1-0.1-0.0-0.0
Patch foraging total patch changes 18 sec0.50.71.00.90.80.8-0.80.80.90.90.8-1.0
Patch foraging total patch changes 24 sec0.91.61.81.01.11.3-1.31.31.31.31.2-1.3
Patch foraging total patch changes 6 sec0.30.50.60.50.70.7-0.70.80.80.80.8-0.6
Patch foraging time to switch 0 sec0.00.00.00.00.10.1-0.10.10.10.10.1-0.0
Patch foraging water rate 0 sec0.00.00.0-0.0-0.2-0.10.1-0.0-0.0-0.0-0.2-0.0
Patch foraging water rate 12 sec0.10.20.40.60.60.5-0.50.50.50.40.4-0.5
Patch foraging water rate 18 sec0.71.11.1-1.1-1.0-1.01.0-1.0-1.0-1.0-1.10.9
Patch foraging water rate 24 sec0.10.10.30.60.40.2-0.20.20.10.10.0-0.3
Patch foraging water rate 6 sec0.00.00.00.20.00.0-0.00.00.00.0-0.0-0.0
Seeking ratio, delayed vs. immediate footshock0.10.10.2-0.3-0.3-0.30.3-0.3-0.4-0.3-0.30.4
Distance traveled before self-admin0.00.00.2-0.5-0.1-0.00.1-0.1-0.1-0.00.1-0.3
Distance traveled after self-admin0.00.00.0-0.20.1-0.10.1-0.2-0.2-0.2-0.10.0
Extensor digitorum longus weight0.31.01.51.11.11.0-1.00.90.90.90.9-1.2
Bone: elastic displacement1.51.82.21.41.41.3-1.31.31.21.31.3-1.5
Bone: elastic work1.41.82.61.31.41.3-1.31.31.31.31.3-1.6
Bone: endosteal estimation0.10.20.30.50.40.4-0.40.50.50.40.4-0.5
Bone: endosteal perimeter0.40.80.9-0.8-1.0-0.90.9-0.9-0.9-0.9-0.90.9
Epididymis fat weight1.13.64.0-1.9-1.9-1.91.9-1.9-1.9-1.9-2.01.8
Delta time in closed arm before/after self-admin0.30.30.40.20.60.6-0.60.60.50.60.7-0.5
Delta time in open arm before/after self-admin0.40.40.9-0.4-1.0-0.70.6-0.6-0.5-0.6-0.70.8
Diff in mean of infusions in LGA sessions1.31.51.91.41.31.2-1.21.21.21.21.1-1.4
Delay discount exponential model param0.10.10.2-0.5-0.2-0.20.3-0.3-0.3-0.3-0.20.2
Extinction: sum of active levers before priming0.30.30.40.10.60.6-0.50.50.40.50.6-0.6
Active lever presses in extinction session 60.00.00.3-0.5-0.1-0.10.1-0.1-0.2-0.1-0.1-0.1
Bone: final force0.00.00.1-0.2-0.1-0.20.2-0.2-0.3-0.2-0.20.0
Bone: final moment0.00.00.10.00.20.1-0.10.10.00.00.1-0.2
Food consumed during 24 hour testing period6.28.69.1-2.9-2.8-3.03.0-3.0-3.0-3.0-2.92.8
Glucose2.13.43.7-1.7-1.7-1.91.9-1.9-1.9-1.9-1.91.6
Heart weight0.71.01.31.11.01.0-1.01.01.01.00.9-0.8
Delay discount hyperbolic model param0.10.10.3-0.6-0.3-0.30.4-0.4-0.4-0.3-0.30.3
Intermittent access intake day 1-15 change0.50.91.2-0.9-1.1-1.01.0-0.9-0.9-0.9-1.10.9
Intermittent access intake escalation0.61.31.6-1.1-1.3-1.21.1-1.1-1.1-1.1-1.21.1
Intermittent access intake escalation 22.32.62.8-1.6-1.7-1.61.6-1.6-1.6-1.6-1.71.6
Intermitt. access day 1 inactive lever presses0.00.10.1-0.2-0.0-0.20.2-0.3-0.3-0.3-0.20.2
Intermitt. access day 15 inactive lever presses0.51.01.6-1.3-1.0-1.01.0-1.0-1.0-1.0-0.80.9
Intermitt. access escalation Index0.00.10.10.2-0.1-0.30.2-0.3-0.2-0.3-0.30.3
Intermittent access day 1 total infusions2.94.86.0-2.5-2.1-2.22.2-2.2-2.2-2.2-2.02.0
Intermittent access day 15 total infusions4.16.16.7-2.5-2.6-2.52.5-2.5-2.4-2.5-2.52.3
Intermittent access terminal intake (last 3 days)4.35.65.7-2.4-2.4-2.42.4-2.4-2.4-2.4-2.42.3
Intermittent access total infusions5.36.26.5-2.5-2.5-2.52.5-2.5-2.5-2.5-2.52.3
Intermittent access day 1 locomotion2.02.63.8-1.9-1.7-1.61.6-1.6-1.6-1.6-1.41.3
Intermittent access day 15 total locomotion1.12.03.1-1.8-1.7-1.31.3-1.3-1.2-1.3-1.31.3
Intermittent access total locomotion2.22.63.8-1.9-1.8-1.61.6-1.5-1.5-1.5-1.51.4
Intermittent access standard deviation2.44.96.2-2.5-2.3-2.22.2-2.2-2.2-2.2-2.11.9
Left kidney weight0.73.15.3-2.3-1.5-1.71.7-1.8-1.9-1.7-1.61.6
Right kidney weight1.25.39.0-3.0-2.1-2.22.2-2.3-2.3-2.2-2.02.2
Cocaine induced anxiety0.10.20.20.40.50.4-0.40.40.40.40.4-0.5
Post-drug Anxiety1.92.02.61.61.61.4-1.41.41.41.41.4-1.3
Baseline Anxiety0.70.81.71.30.90.8-0.90.90.90.90.7-0.7
Tail length0.51.92.5-1.4-1.0-1.41.4-1.6-1.6-1.5-1.31.1
Length with tail0.83.54.2-1.9-1.5-1.91.9-2.0-2.0-2.0-1.81.6
Length without tail0.72.43.2-1.8-1.5-1.51.5-1.5-1.5-1.5-1.51.5
Times rat made contact with spout0.20.20.3-0.5-0.4-0.50.5-0.5-0.5-0.5-0.40.4
Lifetime Intake4.96.06.3-2.5-2.4-2.52.5-2.5-2.5-2.5-2.42.2
Liver weight, left1.01.72.0-1.4-1.1-1.31.3-1.3-1.4-1.3-1.31.2
Liver weight, right1.01.72.5-1.6-1.1-1.21.3-1.3-1.4-1.3-1.11.2
Locomotor activity0.00.00.1-0.1-0.3-0.20.2-0.2-0.1-0.2-0.30.2
Locomotor testing distance1.01.92.2-1.2-1.3-1.41.4-1.4-1.4-1.4-1.51.4
Locomotor testing rearing0.10.20.4-0.2-0.5-0.50.5-0.5-0.4-0.5-0.60.4
Locomotion in novel chamber1.31.72.1-1.3-1.4-1.31.3-1.2-1.2-1.2-1.31.4
Locomotion in novel chamber post-restriction0.60.91.61.21.00.9-0.90.90.90.90.7-1.0
Fecal boli incidents, locomotor time 15.98.59.83.13.12.9-2.82.82.82.82.9-3.0
Change in fecal boli incidents, locomotor task7.17.08.5-2.8-2.9-2.62.6-2.5-2.5-2.5-2.72.7
Time >=10cm from walls, locomotor time 10.10.20.30.40.50.4-0.30.30.30.30.5-0.3
Bouts of movement, locomotor time 10.60.61.01.01.00.7-0.70.60.60.70.7-1.0
Total resting periods, locomotor time 10.50.50.90.90.90.6-0.60.60.50.60.7-0.9
Rest time, locomotor task time 10.40.61.00.80.90.7-0.70.60.60.60.7-1.0
Distance moved, locomotor task time 11.42.12.5-1.4-1.5-1.41.4-1.4-1.4-1.4-1.51.6
Vertical activity count, locomotor time 10.10.20.4-0.3-0.5-0.40.4-0.3-0.3-0.3-0.40.6
Time >=10cm from walls, locomotor time 24.46.57.2-2.4-2.5-2.62.6-2.6-2.6-2.6-2.52.7
Bouts of movement, locomotor time 20.20.30.40.30.60.6-0.50.50.50.50.7-0.5
Total resting periods, locomotor time 20.10.20.30.20.50.4-0.40.40.30.40.5-0.4
Rest time, locomotor task time 21.72.12.51.41.41.4-1.41.41.41.41.4-1.6
Distance moved, locomotor task time 24.85.76.5-2.2-2.3-2.42.4-2.4-2.4-2.4-2.52.4
Vertical activity count, locomotor time 22.12.93.6-1.7-1.7-1.71.7-1.7-1.7-1.7-1.71.9
Light reinforcement 10.10.20.6-0.8-0.3-0.40.5-0.5-0.5-0.5-0.30.6
Light reinforcement 20.00.10.3-0.5-0.1-0.20.2-0.2-0.3-0.3-0.10.3
Bone: marrow area0.10.20.30.50.40.5-0.50.50.50.50.4-0.5
Bone: maximum diameter0.20.40.5-0.6-0.5-0.70.7-0.7-0.7-0.7-0.60.7
Bone: maximum force0.10.30.4-0.6-0.5-0.50.5-0.5-0.5-0.5-0.50.4
Bone: maximum moment0.00.00.0-0.2-0.1-0.10.1-0.1-0.1-0.1-0.1-0.0
Mean time between licks in bursts0.51.31.41.01.01.1-1.21.21.21.21.1-1.1
Mean num. licks in bursts0.00.00.1-0.30.20.1-0.10.0-0.00.00.2-0.1
Cd content in liver3.13.43.7-1.7-1.7-1.91.9-1.9-1.9-1.9-1.91.9
Co content in liver1.21.31.61.31.21.1-1.11.11.21.11.1-1.2
Cu content in liver1.11.31.61.21.11.1-1.11.11.11.11.0-1.3
Fe content in liver0.30.40.70.80.70.6-0.60.60.60.60.5-0.6
K content in liver3.93.84.21.71.92.0-2.02.02.02.02.0-1.9
Mg content in liver1.31.31.81.11.21.1-1.11.11.11.11.1-1.3
Mn content in liver1.51.72.01.31.41.3-1.31.21.21.21.2-1.4
Na content in liver0.10.10.2-0.3-0.1-0.30.3-0.4-0.4-0.4-0.20.3
Rb content in liver2.12.42.81.61.71.5-1.51.51.51.51.5-1.6
Se content in liver4.85.76.92.62.32.3-2.42.42.42.42.2-2.5
Sr content in liver0.10.10.10.20.20.3-0.30.30.30.30.3-0.1
Zn content in liver0.30.30.4-0.6-0.6-0.60.6-0.6-0.6-0.6-0.60.5
Bone: minimum diameter0.81.51.8-1.2-1.0-1.31.3-1.3-1.3-1.3-1.21.0
Time in familiar zone, hab. session 10.60.60.90.70.90.8-0.80.80.80.80.9-0.6
Time in novel zone, hab. session 11.21.21.7-1.0-1.2-1.11.1-1.1-1.1-1.1-1.30.8
Total zone transitions, hab. session 12.33.23.8-1.8-1.9-1.81.8-1.7-1.7-1.7-1.81.9
Total locomotion distance, hab. session 10.91.32.2-1.3-1.4-1.11.1-1.0-0.9-1.0-1.01.5
Locomotion velocity, hab. session 10.60.81.4-1.1-1.2-0.80.8-0.7-0.7-0.7-0.71.2
Time in familiar zone, hab. session 20.00.00.0-0.2-0.20.00.00.00.00.10.10.2
Time in novel zone, hab. session 20.00.00.10.10.1-0.20.2-0.3-0.3-0.3-0.3-0.0
Total zone transitions, hab. session 21.62.02.5-1.6-1.4-1.41.4-1.4-1.4-1.4-1.41.4
Total locomotion distance, hab. session 20.00.00.1-0.3-0.10.00.00.00.00.00.10.1
Locomotion velocity, hab. session 20.00.00.1-0.3-0.10.1-0.10.10.10.10.20.0
Novel to familiar place preference ratio0.91.01.2-1.1-1.1-1.01.0-0.9-0.9-0.9-1.00.9
Novelty place preference0.80.91.1-1.0-1.1-0.90.9-0.9-0.9-0.9-1.00.9
Time in novel zone, NPP test0.60.70.8-0.8-0.9-0.80.8-0.8-0.8-0.8-0.80.8
Total zone transitions, NPP test0.50.71.11.00.70.8-0.80.90.90.90.8-0.7
Total locomotion distance, NPP test0.40.60.80.80.50.8-0.80.80.90.80.8-0.6
Locomotion velocity, NPP test0.30.40.60.60.40.7-0.70.70.80.70.7-0.6
Intraocular pressure0.00.00.10.2-0.10.1-0.10.10.20.1-0.0-0.3
Delta distance traveled before/after self-admin0.20.20.60.70.80.4-0.40.30.30.40.4-0.2
Delta ambulatory time before/after self-admin0.00.00.10.30.30.0-0.0-0.0-0.1-0.0-0.10.1
Parametrial fat weight0.10.20.3-0.6-0.5-0.40.4-0.4-0.4-0.4-0.30.5
Pavlov. Cond. lever latency0.60.81.00.80.80.9-0.90.90.90.91.0-0.9
Pavlov. Cond. magazine entry latency0.81.01.2-1.1-0.8-0.91.0-1.0-1.1-1.0-0.91.1
Pavlov. Cond. change in total contacts0.10.10.20.10.50.4-0.40.40.40.40.4-0.4
Pavlov. Cond. index score0.40.50.6-0.8-0.5-0.60.6-0.7-0.7-0.7-0.60.7
Pavlov. Cond. latency score0.40.50.8-0.9-0.6-0.70.7-0.7-0.7-0.7-0.70.8
Pavlov. Cond. lever contacts0.60.70.9-0.8-0.7-0.80.8-0.9-0.9-0.9-1.00.9
Pavlov. Cond. magazine entry number0.91.21.51.20.91.0-1.11.11.21.11.0-1.1
Pavlov. Cond. intertrial magazine entries0.00.00.10.3-0.10.0-0.10.10.10.1-0.1-0.3
Pavlov. Cond. lever-magazine prob. diff.0.40.40.5-0.7-0.5-0.60.6-0.7-0.7-0.7-0.60.7
Pavlov. Cond. response bias0.91.21.4-1.1-0.9-1.11.1-1.1-1.2-1.1-1.11.2
Pavlov. Cond. lever latency1.72.42.81.41.61.6-1.51.51.51.51.7-1.5
Pavlov. Cond. magazine entry latency0.80.91.2-1.1-1.1-1.00.9-0.9-0.9-0.9-1.00.9
Pavlov. Cond. change in total contacts0.91.51.8-1.1-1.3-1.21.2-1.2-1.2-1.2-1.31.1
Pavlov. Cond. index score1.92.52.8-1.6-1.7-1.61.6-1.6-1.5-1.6-1.71.5
Pavlov. Cond. latency score2.33.13.5-1.7-1.9-1.81.7-1.7-1.7-1.7-1.81.7
Pavlov. Cond. lever contacts2.53.54.1-1.7-2.0-1.91.9-1.8-1.8-1.9-2.01.8
Pavlov. Cond. magazine entry number0.70.91.01.01.00.9-0.90.90.90.90.9-0.9
Pavlov. Cond. intertrial magazine entries0.20.30.60.80.60.5-0.50.50.40.50.5-0.5
Pavlov. Cond. lever-magazine prob. diff.1.62.12.3-1.4-1.5-1.51.4-1.4-1.4-1.4-1.51.3
Pavlov. Cond. response bias2.02.73.0-1.5-1.7-1.71.6-1.6-1.6-1.6-1.71.6
Time in closed arm before self-admin2.12.73.8-1.0-1.5-1.81.7-1.7-1.7-1.8-2.01.5
Time in closed arm after self-admin0.60.61.1-0.5-0.7-0.80.8-0.8-0.8-0.8-1.10.6
Time in open arm before self-admin4.54.95.41.92.12.3-2.22.32.32.32.3-2.3
Time in open arm after self-admin1.31.41.81.00.81.2-1.21.31.31.31.3-1.1
Bone: periosteal estimation0.00.00.00.10.20.1-0.10.10.00.10.1-0.2
Bone: periosteal perimeter1.22.12.3-1.5-1.3-1.41.5-1.5-1.5-1.5-1.41.4
Bone: post-yield work0.00.00.1-0.1-0.3-0.20.2-0.1-0.1-0.2-0.30.2
Progressive ratio test 1 active lever presses3.34.04.4-2.0-1.9-2.12.1-2.1-2.1-2.1-1.91.8
Progressive ratio test 1 breakpoint3.34.04.4-2.0-1.9-2.02.1-2.1-2.1-2.1-1.91.8
Progressive ratio test 1 inactive lever presses1.21.72.2-1.5-1.3-1.31.3-1.4-1.4-1.4-1.21.1
Progressive ratio test 2 active lever presses6.37.48.2-2.9-2.7-2.72.7-2.8-2.8-2.7-2.62.6
Progressive ratio test 2 breakpoint6.77.78.4-2.9-2.8-2.82.8-2.8-2.8-2.8-2.72.7
Progressive ratio test 2 inactive lever presses3.15.16.1-2.5-2.2-2.22.3-2.3-2.3-2.2-2.12.2
Incentive Sensitization - Responses3.95.46.6-2.6-2.3-2.32.3-2.3-2.3-2.3-2.22.3
Incentive Sensitization - Breakpoint4.05.26.2-2.5-2.3-2.32.3-2.3-2.3-2.2-2.22.3
Sum of active levers in priming session hrs 5-61.31.21.60.81.21.2-1.21.11.11.11.1-1.1
Progressive ratio0.40.60.7-0.7-0.7-0.70.8-0.8-0.8-0.8-0.80.7
Food seeking constrained by brief footshock0.81.01.4-1.2-1.0-1.00.9-1.0-0.9-0.9-1.20.7
Seeking ratio, punishment vs. effort0.00.10.10.20.10.2-0.30.30.30.30.2-0.3
Retroperitoneal fat weight11.850.251.7-7.2-7.1-7.17.1-7.0-7.0-7.0-7.17.1
Reaction time number correct0.00.00.10.20.30.1-0.20.10.10.10.1-0.2
Reaction time mean minus median0.10.20.6-0.8-0.5-0.40.5-0.4-0.5-0.4-0.40.3
Reaction time mean minus median AUC0.10.30.5-0.7-0.5-0.50.5-0.5-0.5-0.5-0.50.4
Reaction time num false alarms1.52.12.41.51.41.4-1.51.41.51.41.4-1.6
Reaction time num false alarms AUC2.13.33.92.01.81.8-1.81.81.81.81.7-1.9
Reaction time trials correct on left0.00.00.10.20.30.1-0.20.10.10.10.1-0.2
Reaction time trials on left0.00.10.10.30.40.2-0.30.20.20.20.2-0.3
Reaction time mean0.20.40.5-0.7-0.5-0.60.6-0.6-0.7-0.6-0.60.5
Reaction time mean AUC0.40.60.8-0.8-0.7-0.80.8-0.8-0.9-0.8-0.80.7
Median of all reaction times0.40.50.6-0.7-0.6-0.70.7-0.8-0.8-0.7-0.70.6
Reaction time omissions0.91.31.40.91.11.2-1.21.11.11.21.1-1.2
Reaction time false alarm rate2.43.33.61.91.71.8-1.81.81.81.81.8-1.9
Reaction time premature initiation rate0.20.20.40.60.60.4-0.40.40.40.40.5-0.5
Reaction time premature initiations0.20.30.60.60.80.5-0.50.40.40.40.5-0.6
Std. dev. reaction times0.00.10.1-0.4-0.2-0.20.3-0.3-0.3-0.3-0.30.1
Reaction time trials completed0.00.10.10.30.40.2-0.30.20.20.20.2-0.3
Reaction time trials AUC0.00.00.00.10.20.0-0.1-0.00.0-0.00.0-0.1
Run reversals in cocaine runway, females0.20.20.3-0.5-0.3-0.40.4-0.4-0.5-0.4-0.40.3
Run reversals in cocaine runway, males4.64.64.82.02.22.2-2.22.22.12.22.2-2.2
Latency to leave start box in cocaine runway0.30.30.60.20.30.6-0.50.60.60.60.6-0.7
Latency to leave start box in cocaine runway, F0.00.10.2-0.4-0.20.1-0.10.20.20.20.1-0.4
Latency to leave start box in cocaine runway, M0.40.40.70.80.60.6-0.60.60.60.60.7-0.5
Std. dev. time between licks in bursts0.30.40.90.90.60.6-0.60.60.60.60.5-0.7
Total sessions with >9 infusions2.12.53.0-1.7-1.5-1.61.6-1.7-1.6-1.6-1.51.3
Short access day 1 total inactive lever presses0.91.21.3-1.1-1.2-1.21.1-1.1-1.1-1.1-1.10.9
Short access day 10 total inactive lever presses0.00.10.2-0.4-0.4-0.20.3-0.2-0.3-0.3-0.30.4
Short access day 1 total infusions3.34.34.9-2.0-1.9-2.22.2-2.2-2.2-2.2-2.01.8
Short access day 10 total infusions3.14.04.7-2.2-2.1-2.02.0-2.0-2.0-2.0-2.01.7
Short access total infusions3.54.54.9-2.2-2.1-2.22.2-2.2-2.2-2.2-2.01.8
Short access day 1 locomotion2.53.23.7-1.8-1.9-1.81.8-1.8-1.8-1.8-1.71.5
Short access day 10 total locomotion2.44.46.5-2.5-2.3-2.12.1-2.1-2.1-2.0-2.01.8
Short access total locomotion3.33.95.3-2.3-2.1-2.02.0-2.0-1.9-1.9-1.81.7
One hour access (0.3 mA shock)5.05.88.3-2.9-2.5-2.32.4-2.3-2.4-2.3-2.22.3
Compulsive drug intake4.04.85.41.92.12.2-2.22.22.22.22.3-2.2
One hour access (shock baseline)6.910.611.4-3.4-3.3-3.33.3-3.3-3.3-3.2-3.23.2
Social response proportion4.45.05.52.22.32.3-2.22.22.22.22.3-2.3
Social responses0.00.00.1-0.3-0.1-0.20.2-0.2-0.3-0.2-0.10.1
Social time2.12.83.41.81.61.6-1.71.71.71.71.6-1.6
Soleus weight1.44.04.31.81.92.0-2.02.12.12.12.0-1.9
Bone: stiffness0.71.11.3-1.2-1.1-1.01.1-1.0-1.1-1.1-1.01.0
Tibialis anterior weight2.910.010.83.33.23.1-3.13.13.13.13.1-3.3
Time to tail flick, vehicle, before self-admin2.52.63.4-1.8-1.8-1.61.6-1.5-1.5-1.5-1.51.7
Time to tail flick, vehicle, after self-admin4.05.35.7-2.0-2.4-2.42.4-2.4-2.3-2.4-2.42.1
Time to tail flick, test, before self-admin2.12.23.0-1.1-1.5-1.51.4-1.4-1.4-1.5-1.61.7
Time to tail flick, test, after self-admin5.05.16.6-1.6-2.5-2.32.3-2.2-2.2-2.3-2.62.3
Delta time to tail flick, vehicle, before/after SA0.10.10.20.2-0.2-0.30.3-0.3-0.3-0.3-0.50.1
Delta time to tail flick, test, before/after SA0.10.10.2-0.1-0.4-0.30.3-0.3-0.2-0.3-0.40.1
Tibia length0.20.71.30.81.10.8-0.80.70.60.70.8-1.0
Ambulatory time before self-admin0.00.10.3-0.00.30.2-0.20.20.20.20.4-0.5
Ambulatory time after self-admin0.20.20.4-0.3-0.1-0.40.5-0.6-0.6-0.6-0.50.4
Bone: tissue strength0.00.00.0-0.1-0.10.1-0.10.10.10.10.0-0.0
Total heroin consumption1.11.31.70.81.31.2-1.11.11.01.11.3-1.3
Bone: trabecular number0.50.91.0-0.8-1.0-0.90.9-0.9-0.9-0.9-1.01.0
Bone: trabecular spacing0.10.20.3-0.5-0.4-0.40.4-0.4-0.4-0.4-0.30.3
Bone: trabecular thickness0.50.70.7-0.8-0.8-0.80.8-0.8-0.8-0.8-0.80.8
Bone: trabecular tissue density0.71.11.50.81.01.1-1.11.11.11.11.2-0.8
Water consumed over 24 hours0.40.60.7-0.7-0.7-0.80.8-0.8-0.8-0.8-0.80.6
Number of responses in last shaping day3.43.84.1-1.9-1.8-2.02.0-2.0-2.0-2.0-1.81.9