Hub : Genes

Abca7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression Abca7 0.33 0.17 1.2e-06 0.19 0.17 0.19 0.19 2.1e-05 7.4e-05 2.8e-05 2.9e-05
2 Adipose isoform ratio XR_005486555.1 0.03 0.02 4.1e-03 0.02 0.01 0.01 0.01 2.0e-03 2.0e-02 6.3e-02 7.5e-03
3 BLA intron excision ratio chr7_9696516_9696633 0.06 0.05 3.4e-03 0.04 0.04 0.04 0.04 1.9e-03 5.3e-03 5.2e-03 5.7e-03
4 OFC gene expression Abca7 0.14 0.1 1.6e-03 0.09 0.08 0.07 0.08 4.2e-03 5.8e-03 8.5e-03 6.7e-03
5 Brain intron excision ratio chr7_9710403_9711217 0.02 0.02 9.5e-03 0.01 0.02 0.01 0.01 1.9e-02 1.1e-02 3.5e-02 1.6e-02
6 BLA gene expression Abca7 0.5 0.18 0.0e+00 0.42 0.46 0.44 0.43 2.5e-24 6.3e-27 6.3e-26 7.0e-25
7 Brain isoform ratio XM_006240871.4 0.03 0.02 2.1e-03 0.01 0.01 0.01 0.01 1.5e-02 1.9e-02 7.4e-02 3.1e-02
8 NAcc alternative polyA XM_039078646.1 0.04 0.03 6.1e-05 0.04 0.04 0.04 0.04 1.5e-05 4.1e-05 5.0e-05 2.1e-05
9 OFC mRNA stability Abca7 0.28 0.15 8.9e-07 0.24 0.24 0.24 0.25 1.9e-06 2.5e-06 2.3e-06 1.1e-06
10 BLA isoform ratio XR_005486559.1 0.52 0.22 0.0e+00 0.36 0.35 0.35 0.36 3.3e-20 1.1e-19 1.0e-19 3.8e-20
11 PL isoform ratio NM_207598.2 0.04 0.03 5.3e-05 0.04 0.03 0.02 0.04 2.4e-05 1.4e-04 1.1e-03 9.5e-05
12 BLA alternative polyA XM_006240874.4 0.06 0.05 3.1e-03 0.05 0.04 0.03 0.04 1.1e-03 2.8e-03 1.6e-02 2.3e-03
13 BLA alternative polyA XM_039078646.1 0.08 0.06 8.8e-04 0.06 0.05 0.05 0.05 3.4e-04 1.0e-03 1.4e-03 1.1e-03
14 BLA mRNA stability Abca7 0.53 0.15 0.0e+00 0.5 0.47 0.48 0.47 4.2e-30 7.2e-28 9.9e-29 5.1e-28
15 NAcc alternative polyA XM_006240874.4 0.04 0.03 6.2e-05 0.04 0.04 0.04 0.04 1.3e-05 3.6e-05 3.1e-05 2.4e-05
16 Brain mRNA stability Abca7 0.58 0.15 0.0e+00 0.38 0.37 0.38 0.38 9.6e-37 3.4e-36 7.9e-37 4.1e-37
17 PL gene expression Abca7 0.44 0.15 0.0e+00 0.51 0.51 0.52 0.52 1.1e-64 2.5e-65 1.1e-65 3.1e-66
18 NAcc gene expression Abca7 0.28 0.13 0.0e+00 0.29 0.3 0.3 0.31 6.1e-34 2.4e-35 2.0e-35 2.1e-36
19 IL mRNA stability Abca7 0.55 0.18 5.0e-10 0.22 0.18 0.2 0.2 6.0e-06 3.3e-05 1.3e-05 1.6e-05
20 pVTA mRNA stability Abca7 0.32 0.16 6.4e-13 0.3 0.29 0.28 0.3 3.0e-13 7.3e-13 9.2e-13 2.8e-13
21 Adipose gene expression Abca7 0.06 0.04 3.0e-06 0.05 0.04 0.05 0.04 6.7e-06 1.1e-05 6.3e-06 9.2e-06
22 PL mRNA stability Abca7 0.43 0.16 0.0e+00 0.46 0.46 0.47 0.47 2.1e-56 1.2e-56 2.2e-57 2.7e-58
23 NAcc mRNA stability Abca7 0.19 0.1 0.0e+00 0.21 0.21 0.21 0.21 9.6e-24 1.8e-23 1.1e-23 1.2e-23
24 Brain gene expression Abca7 0.28 0.13 0.0e+00 0.25 0.24 0.25 0.24 6.1e-23 2.8e-22 5.1e-23 1.5e-22
25 pVTA gene expression Abca7 0.28 0.15 6.9e-09 0.16 0.21 0.19 0.2 1.3e-07 2.6e-09 1.1e-08 4.6e-09
26 BLA isoform ratio NM_207598.2 0.1 0.07 3.0e-04 0.06 0.06 0.06 0.06 4.1e-04 3.2e-04 2.7e-04 3.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.50.84.10.9-1.11.11.0-0.10.61.0-1.0-0.4-0.70.70.7-0.70.70.7-0.70.70.60.6-0.6-0.6-0.60.6-1.02.01.5
Area under the delay curve2.12.32.9-1.71.4-1.4-1.2-1.71.61.6-1.6-1.4-1.51.51.5-1.51.51.5-1.61.61.61.4-1.4-1.5-1.51.5-1.51.21.4
BMI with tail6.420.723.9-4.74.8-4.8-4.8-4.94.64.5-4.5-4.7-4.74.74.7-4.74.74.7-4.54.54.64.6-4.6-4.6-4.64.6-4.23.03.5
BMI without tail2.14.49.1-2.73.0-3.0-3.0-2.42.11.8-1.8-2.2-1.91.91.9-1.91.91.9-2.12.02.12.0-2.0-2.1-2.02.1-1.50.60.9
Body weight1.25.06.0-2.32.4-2.4-2.5-2.42.32.1-2.1-2.4-2.32.32.3-2.32.32.3-2.32.22.32.3-2.3-2.3-2.32.3-2.01.41.6
Weight adjusted by age0.40.41.8-1.31.3-1.3-1.2-0.80.50.5-0.5-0.5-0.40.40.4-0.40.40.4-0.40.50.40.4-0.4-0.4-0.40.4-0.2-0.5-0.2
Bone surface0.61.05.11.8-2.02.01.90.60.20.5-0.50.0-0.40.40.4-0.40.40.4-0.30.30.20.3-0.3-0.2-0.30.2-0.82.31.6
Bone volume0.61.05.31.7-1.91.91.90.50.30.6-0.6-0.0-0.50.50.5-0.50.50.5-0.40.40.30.3-0.3-0.3-0.30.3-0.92.31.6
Breakpoint value in progressive ratio session5.76.37.22.2-2.02.11.92.5-2.6-2.52.52.52.6-2.6-2.62.6-2.6-2.62.6-2.6-2.6-2.62.62.62.6-2.52.6-2.3-2.7
Number of licking bursts0.10.10.7-0.90.5-0.5-0.6-0.30.0-0.10.10.10.0-0.0-0.00.0-0.0-0.00.1-0.2-0.1-0.20.20.20.2-0.20.2-0.8-0.7
Context. condit. distance diff. score0.20.20.7-0.30.8-0.8-0.8-0.40.40.0-0.0-0.60.0-0.0-0.00.0-0.0-0.0-0.50.40.60.6-0.6-0.6-0.60.6-0.20.00.1
Locomotion velocity, session 10.40.41.61.2-1.31.21.30.8-0.5-0.30.30.60.3-0.3-0.30.3-0.3-0.30.5-0.5-0.5-0.50.50.50.5-0.50.20.50.3
Locomotion distance, session 10.40.63.81.9-1.41.41.40.8-0.1-0.30.30.10.2-0.2-0.20.2-0.2-0.2-0.10.10.10.1-0.1-0.1-0.10.1-0.51.51.1
Locomotion velocity, session 23.74.311.53.4-3.03.03.02.6-1.9-2.12.11.92.0-2.0-2.02.0-2.0-2.01.8-1.8-1.7-1.71.71.71.7-1.71.3-0.1-0.5
Locomotion distance, session 21.31.86.92.5-2.62.62.61.7-1.0-0.80.81.20.9-0.9-0.90.9-0.9-0.90.9-0.9-1.0-1.01.01.01.0-1.00.30.90.5
Locomotion velocity, session 37.28.49.92.7-2.52.52.52.9-3.0-3.13.12.93.1-3.1-3.13.1-3.1-3.12.9-2.9-2.9-2.92.92.92.9-2.92.8-2.4-2.6
Locomotion distance, session 30.00.00.20.00.3-0.3-0.30.0-0.1-0.30.3-0.00.2-0.2-0.20.2-0.2-0.20.0-0.10.0-0.00.00.00.0-0.00.2-0.4-0.3
Stereotopy head waving bouts, day 35.26.28.83.0-2.72.72.82.8-2.6-2.72.72.42.7-2.7-2.72.7-2.7-2.72.3-2.4-2.3-2.32.32.32.3-2.32.1-1.4-1.6
Stereotopy head waving duration, day 36.37.68.92.9-2.92.82.93.0-2.8-2.92.92.72.9-2.9-2.92.9-2.9-2.92.7-2.7-2.7-2.62.62.72.6-2.62.4-1.8-2.0
Locomotion velocity, session 70.80.91.81.0-0.40.30.40.8-0.8-1.41.40.71.3-1.3-1.31.3-1.3-1.30.7-0.8-0.7-0.70.70.70.7-0.70.9-0.9-1.0
Locomotion distance, session 70.20.21.1-0.71.0-1.0-1.0-0.50.3-0.00.0-0.30.1-0.1-0.10.1-0.1-0.1-0.20.20.20.2-0.2-0.2-0.20.20.1-0.6-0.5
Stereotopy head waving bouts, day 70.10.10.80.9-0.60.60.60.3-0.0-0.10.1-0.10.0-0.0-0.00.0-0.0-0.0-0.10.10.10.2-0.2-0.2-0.20.2-0.30.70.6
Stereotopy head waving duration, day 70.20.31.51.2-1.01.01.10.6-0.3-0.30.30.30.2-0.2-0.20.2-0.2-0.20.2-0.2-0.2-0.20.20.20.2-0.2-0.10.60.5
Locomotion velocity, session 80.80.94.12.0-1.61.61.61.1-0.6-1.01.00.51.0-1.0-1.01.0-1.0-1.00.4-0.4-0.4-0.40.40.40.4-0.40.00.70.4
Locomotion distance, session 80.20.31.61.3-0.80.80.80.7-0.4-0.60.60.30.7-0.7-0.70.7-0.7-0.70.2-0.3-0.2-0.20.20.20.2-0.20.10.30.2
Degree of sensitization distance0.30.30.5-0.50.6-0.6-0.6-0.60.70.5-0.5-0.7-0.50.50.5-0.50.50.5-0.70.60.70.7-0.7-0.7-0.70.7-0.60.50.5
Degree of sensitization stereotypy2.12.32.9-0.91.0-1.0-1.0-1.41.51.6-1.6-1.5-1.71.71.7-1.71.71.7-1.61.61.61.6-1.6-1.6-1.61.6-1.61.61.7
Conditioned locomotion1.11.33.3-1.71.8-1.8-1.8-1.51.11.0-1.0-1.1-1.01.01.0-1.01.01.0-1.01.01.01.0-1.0-1.0-1.01.0-0.7-0.00.2
Cocaine response after cond. corrected4.55.011.6-3.43.2-3.2-3.2-2.82.22.3-2.3-2.3-1.91.91.9-1.91.91.9-2.12.02.12.1-2.1-2.1-2.02.1-1.60.41.0
Cocaine response after cond. not corrected4.75.111.5-3.43.4-3.4-3.3-2.82.22.2-2.2-2.3-1.91.91.9-1.91.91.9-2.12.02.12.1-2.1-2.1-2.12.1-1.60.30.9
Cocaine response before conditioning0.50.61.21.1-0.80.80.80.9-0.8-1.01.00.70.7-0.7-0.70.7-0.7-0.70.7-0.7-0.7-0.70.70.70.7-0.70.7-0.4-0.6
Saline control response0.00.10.1-0.30.3-0.3-0.2-0.30.20.2-0.2-0.2-0.30.30.3-0.30.30.3-0.20.20.20.2-0.2-0.2-0.20.2-0.10.00.1
Bone: connectivity density0.60.93.50.3-0.40.40.3-0.40.91.1-1.1-0.7-0.90.90.9-0.90.90.9-0.91.00.90.9-0.9-0.8-0.90.9-1.11.91.4
Bone: cortical apparent density0.91.22.2-1.50.9-0.9-0.9-1.21.11.4-1.4-1.0-1.21.21.2-1.21.21.2-1.01.00.91.0-1.0-0.9-1.01.0-1.10.80.9
Bone: cortical area0.81.11.9-0.40.4-0.4-0.5-0.91.11.0-1.0-1.1-1.21.21.2-1.21.21.2-1.21.21.11.1-1.1-1.1-1.11.1-1.21.41.2
Bone: cortical porosity0.40.41.21.1-1.11.11.10.8-0.5-0.50.50.60.5-0.5-0.50.5-0.5-0.50.5-0.5-0.5-0.60.60.50.6-0.50.30.1-0.0
Bone: cortical porosity0.20.20.90.9-0.80.80.80.20.10.1-0.1-0.0-0.10.10.1-0.10.10.1-0.20.20.20.2-0.2-0.2-0.20.2-0.40.90.7
Bone: cortical thickness1.32.22.6-1.01.0-1.0-1.0-1.41.51.5-1.5-1.5-1.61.61.6-1.61.61.6-1.51.61.51.5-1.5-1.5-1.51.5-1.51.51.5
Bone: cortical thickness0.10.10.8-0.80.7-0.7-0.7-0.2-0.1-0.10.10.10.0-0.0-0.00.0-0.0-0.00.2-0.2-0.2-0.20.20.20.2-0.20.4-0.9-0.6
Bone: cortical tissue density0.60.81.8-1.30.8-0.7-0.8-1.00.91.2-1.2-0.8-1.01.01.0-1.01.01.0-0.80.80.70.8-0.8-0.7-0.80.8-0.90.60.8
Condit. Reinf. active minus inactive responses4.65.16.32.4-2.22.22.22.5-2.4-2.52.52.32.3-2.3-2.32.3-2.3-2.32.3-2.4-2.2-2.22.22.22.2-2.22.2-1.8-1.9
Condit. Reinf. active-inactive response ratio2.32.53.41.0-1.11.11.11.5-1.7-1.51.51.71.5-1.5-1.51.5-1.5-1.51.8-1.8-1.7-1.71.71.71.7-1.71.8-1.8-1.8
Condit. Reinf. active responses3.64.48.62.9-2.72.62.72.5-2.1-2.22.22.12.0-2.0-2.02.0-2.0-2.02.0-2.1-2.0-2.02.02.02.0-2.01.7-0.8-1.1
Condit. Reinf. inactive responses0.81.04.32.1-1.81.81.81.2-0.8-0.80.80.90.7-0.7-0.70.7-0.7-0.70.7-0.7-0.7-0.70.70.70.7-0.70.30.60.3
Incentive salience index mean2.32.75.92.4-2.12.02.02.0-1.7-1.81.81.61.6-1.6-1.61.6-1.6-1.61.6-1.6-1.5-1.51.51.51.5-1.51.4-0.7-0.9
Condit. Reinf. lever presses0.40.52.71.4-1.11.11.10.40.20.2-0.2-0.1-0.40.40.4-0.40.40.4-0.30.30.30.3-0.3-0.3-0.30.3-0.71.61.3
Condit. Reinf. active minus inactive responses2.22.74.00.8-1.11.11.11.4-1.7-1.61.61.81.5-1.5-1.51.5-1.5-1.51.8-1.8-1.9-1.91.91.91.9-1.91.8-2.0-1.9
Condit. Reinf. active-inactive response ratio0.20.20.9-0.80.2-0.2-0.2-0.1-0.30.1-0.10.50.0-0.0-0.00.0-0.0-0.00.5-0.5-0.6-0.60.60.60.6-0.60.5-1.0-0.7
Condit. Reinf. active responses1.92.63.31.0-1.31.31.31.5-1.7-1.71.71.81.5-1.5-1.51.5-1.5-1.51.8-1.7-1.8-1.81.81.81.8-1.81.7-1.7-1.7
Condit. Reinf. inactive responses1.11.32.21.0-0.90.90.91.2-1.2-1.51.51.11.2-1.2-1.21.2-1.2-1.21.1-1.1-1.1-1.11.11.11.1-1.11.1-1.1-1.1
Condit. Reinf. lever presses2.23.13.91.2-1.21.21.21.6-1.9-1.71.71.91.6-1.6-1.61.6-1.6-1.61.9-1.9-1.9-1.91.91.91.9-1.92.0-1.9-2.0
Condit. Reinf. lever reinforcers received1.52.03.30.7-0.90.90.91.2-1.5-1.51.51.61.3-1.3-1.31.3-1.3-1.31.6-1.5-1.7-1.71.71.71.7-1.71.6-1.8-1.7
Conditioned reinforcement - actives1.81.82.71.6-1.41.41.31.5-1.4-1.41.41.21.4-1.4-1.41.4-1.4-1.41.4-1.4-1.3-1.21.21.31.2-1.21.4-1.0-1.1
Conditioned reinforcement - inactives0.40.41.3-0.81.1-1.1-1.1-0.70.50.5-0.5-0.9-0.50.50.5-0.50.50.5-0.60.60.60.8-0.8-0.6-0.70.6-0.3-0.00.3
Conditioned locomotion6.78.09.13.0-2.82.82.73.0-2.9-2.82.82.92.9-2.9-2.92.9-2.9-2.92.9-2.9-2.9-2.92.92.92.9-2.92.8-2.1-2.4
Patch foraging indifference point 0 sec0.20.30.5-0.30.3-0.3-0.2-0.50.60.6-0.6-0.5-0.70.70.7-0.70.70.7-0.60.50.50.5-0.5-0.5-0.50.5-0.60.70.6
Patch foraging indifference point AUC0.70.81.00.8-0.80.80.90.9-1.0-0.80.81.00.8-0.8-0.80.8-0.8-0.81.0-1.0-1.0-1.01.01.01.0-1.00.9-0.8-0.9
Delay disc. indifference point, 0s delay8.29.013.4-1.71.6-1.7-1.5-2.73.13.2-3.2-2.9-3.23.23.2-3.23.23.2-3.23.23.13.1-3.1-3.1-3.13.1-3.43.73.6
Delay disc. indifference point, 16s delay0.10.10.3-0.60.3-0.2-0.3-0.30.30.4-0.4-0.3-0.30.30.3-0.30.30.3-0.30.30.30.3-0.3-0.3-0.30.3-0.30.20.2
Delay disc. indifference point, 2s delay5.86.47.4-2.12.1-2.2-2.0-2.62.72.6-2.6-2.5-2.62.62.6-2.62.62.6-2.72.72.72.5-2.5-2.6-2.62.5-2.72.52.5
Delay disc. indifference point, 24s delay0.90.91.7-1.31.2-1.1-1.2-1.10.91.0-1.0-0.9-1.01.01.0-1.01.01.0-0.80.90.80.8-0.8-0.9-0.90.9-0.80.40.5
Delay disc. indifference point, 4s delay0.90.91.2-0.80.7-0.7-0.6-1.01.01.0-1.0-0.9-1.01.01.0-1.01.01.0-1.01.01.00.9-0.9-1.0-1.01.0-1.01.01.1
Delay disc. indifference point, 8s delay1.01.02.5-1.61.2-1.4-1.0-1.31.21.0-1.0-0.9-0.90.90.9-0.90.90.9-1.11.11.10.9-0.9-1.0-0.90.9-0.90.40.6
Indifference point function ln k0.20.30.7-0.80.8-0.8-0.8-0.60.50.5-0.5-0.6-0.50.50.5-0.50.50.5-0.50.50.50.5-0.5-0.5-0.50.5-0.40.10.2
Indifference point function log k0.20.30.7-0.80.8-0.8-0.8-0.60.50.5-0.5-0.6-0.50.50.5-0.50.50.5-0.50.50.50.5-0.5-0.5-0.50.5-0.40.10.2
Patch foraging total patch changes 0 sec0.10.20.2-0.30.3-0.3-0.2-0.40.40.4-0.4-0.4-0.50.50.5-0.50.50.5-0.50.40.40.4-0.4-0.4-0.40.4-0.40.40.4
Patch foraging total patch changes 12 sec0.20.30.8-0.80.9-0.9-0.9-0.70.60.5-0.5-0.5-0.50.50.5-0.50.50.5-0.50.50.50.4-0.4-0.5-0.40.5-0.30.10.1
Patch foraging total patch changes 18 sec1.11.41.71.2-1.21.21.21.2-1.2-1.21.21.31.1-1.1-1.11.1-1.1-1.11.2-1.3-1.2-1.31.31.21.3-1.31.1-0.9-1.0
Patch foraging total patch changes 24 sec0.00.10.20.2-0.40.40.40.2-0.2-0.00.00.3-0.00.00.0-0.00.00.00.2-0.2-0.2-0.30.30.20.3-0.30.10.0-0.1
Patch foraging total patch changes 6 sec0.20.20.60.5-0.80.80.80.5-0.5-0.30.30.60.4-0.4-0.40.4-0.4-0.40.5-0.5-0.5-0.60.60.50.5-0.50.3-0.1-0.2
Patch foraging time to switch 0 sec1.42.15.50.10.3-0.3-0.3-0.91.41.3-1.3-1.6-1.21.21.2-1.21.21.2-1.71.61.71.7-1.7-1.7-1.81.7-1.82.32.1
Patch foraging water rate 0 sec0.30.52.6-1.11.1-1.1-1.1-0.3-0.2-0.50.50.30.4-0.4-0.40.4-0.4-0.40.4-0.4-0.4-0.50.50.40.5-0.50.7-1.6-1.4
Patch foraging water rate 12 sec1.01.55.7-2.42.2-2.2-2.2-1.61.01.0-1.0-1.0-1.11.11.1-1.11.11.1-0.80.80.80.7-0.8-0.8-0.80.8-0.5-0.6-0.2
Patch foraging water rate 18 sec0.81.15.9-1.41.2-1.2-1.2-0.2-0.6-0.70.70.70.6-0.6-0.60.6-0.6-0.60.9-0.8-0.9-0.90.90.91.0-0.91.3-2.4-2.0
Patch foraging water rate 24 sec0.60.84.1-2.01.9-1.9-2.0-1.00.30.1-0.1-0.2-0.10.10.1-0.10.10.1-0.00.0-0.0-0.10.10.10.1-0.10.5-1.7-1.3
Patch foraging water rate 6 sec0.60.93.5-0.70.5-0.5-0.50.2-0.7-0.70.70.90.7-0.7-0.70.7-0.7-0.70.9-0.9-1.0-1.01.01.01.0-1.01.2-1.9-1.7
Seeking ratio, delayed vs. immediate footshock3.94.56.02.2-2.42.42.52.3-2.2-2.22.22.22.1-2.1-2.12.1-2.1-2.12.1-2.1-2.1-2.12.12.12.1-2.11.8-1.3-1.6
Distance traveled before self-admin0.70.81.2-0.60.4-0.5-0.5-0.80.91.0-1.0-0.9-0.90.90.9-0.90.90.9-0.90.90.91.0-1.0-0.9-0.90.9-1.01.01.1
Distance traveled after self-admin0.40.40.80.8-0.90.80.80.8-0.7-0.60.60.60.6-0.6-0.60.6-0.6-0.60.6-0.6-0.6-0.60.60.60.6-0.60.5-0.2-0.3
Extensor digitorum longus weight4.116.124.1-4.54.9-4.9-4.9-4.54.13.6-3.6-4.3-3.93.93.9-3.93.93.9-4.14.04.14.1-4.1-4.1-4.14.1-3.42.02.5
Bone: elastic displacement0.10.10.40.2-0.60.60.60.3-0.4-0.00.00.50.2-0.2-0.20.2-0.2-0.20.5-0.4-0.5-0.50.50.50.5-0.50.2-0.2-0.1
Bone: elastic work0.30.40.8-0.70.4-0.4-0.4-0.70.70.9-0.9-0.6-0.60.60.6-0.60.60.6-0.60.60.70.6-0.6-0.7-0.60.6-0.70.60.7
Bone: endosteal estimation0.20.30.6-0.40.4-0.4-0.4-0.50.60.4-0.4-0.7-0.60.60.6-0.60.60.6-0.70.60.70.7-0.7-0.7-0.70.7-0.80.50.6
Bone: endosteal perimeter0.20.41.31.1-0.90.90.90.8-0.6-0.70.70.60.6-0.6-0.60.6-0.6-0.60.5-0.5-0.5-0.50.50.50.5-0.50.4-0.0-0.2
Epididymis fat weight0.30.81.00.7-0.60.60.60.9-0.9-0.90.90.90.9-0.9-0.90.9-0.9-0.90.9-0.9-0.9-1.01.01.01.0-1.01.0-0.9-1.0
Delta time in closed arm before/after self-admin0.80.73.4-1.81.8-1.8-1.7-1.10.50.4-0.4-0.6-0.50.50.5-0.50.50.5-0.40.40.40.4-0.4-0.4-0.40.40.0-1.0-0.5
Delta time in open arm before/after self-admin1.21.21.7-0.80.6-0.7-0.7-1.11.21.3-1.3-1.0-1.21.21.2-1.21.21.2-1.11.11.11.0-1.0-1.1-1.01.1-1.21.21.2
Diff in mean of infusions in LGA sessions2.12.32.61.5-1.41.51.41.6-1.6-1.41.41.61.6-1.6-1.61.6-1.6-1.61.6-1.5-1.6-1.61.61.51.5-1.51.4-1.2-1.4
Delay discount exponential model param2.02.12.81.7-1.41.41.21.6-1.6-1.51.51.31.5-1.5-1.51.5-1.5-1.51.5-1.5-1.5-1.31.31.51.4-1.41.4-1.1-1.3
Extinction: sum of active levers before priming1.41.42.70.8-0.50.60.41.1-1.2-1.21.21.11.3-1.3-1.31.3-1.3-1.31.2-1.2-1.2-1.21.21.21.2-1.11.3-1.4-1.6
Active lever presses in extinction session 62.12.02.61.5-1.61.51.51.6-1.5-1.21.21.61.4-1.4-1.41.4-1.4-1.41.5-1.4-1.5-1.51.51.41.5-1.41.3-0.9-1.1
Bone: final force1.42.32.9-1.11.0-1.0-1.1-1.51.61.4-1.4-1.6-1.61.61.6-1.61.61.6-1.71.61.71.6-1.6-1.6-1.61.6-1.71.51.5
Bone: final moment1.11.82.3-1.00.9-0.9-0.9-1.31.41.3-1.3-1.4-1.41.41.4-1.41.41.4-1.51.41.51.5-1.5-1.4-1.41.4-1.51.31.3
Food consumed during 24 hour testing period0.50.61.9-1.40.9-0.9-1.0-0.90.80.8-0.8-0.8-0.60.60.6-0.60.60.6-0.80.70.80.7-0.7-0.7-0.70.7-0.80.20.4
Glucose1.52.33.4-1.81.6-1.6-1.6-1.71.51.6-1.6-1.5-1.61.61.6-1.61.61.6-1.51.51.51.4-1.4-1.5-1.41.5-1.41.01.1
Heart weight0.30.40.9-0.0-0.20.20.30.4-0.7-0.40.40.80.3-0.3-0.30.3-0.3-0.30.8-0.8-0.8-0.80.80.80.8-0.80.9-1.0-0.9
Delay discount hyperbolic model param2.82.93.61.9-1.61.71.41.9-1.9-1.81.81.61.7-1.7-1.71.7-1.7-1.71.8-1.8-1.8-1.61.61.81.7-1.71.7-1.4-1.5
Intermittent access intake day 1-15 change6.56.47.62.3-2.22.22.22.6-2.7-2.82.82.62.6-2.6-2.62.6-2.6-2.62.6-2.6-2.6-2.52.52.52.5-2.52.6-2.2-2.4
Intermittent access intake escalation6.66.47.81.9-1.71.71.82.4-2.7-2.82.82.52.7-2.7-2.72.7-2.7-2.72.7-2.6-2.6-2.62.62.62.6-2.62.7-2.7-2.8
Intermittent access intake escalation 28.18.09.82.1-2.02.02.02.7-2.9-2.92.92.92.9-2.9-2.92.9-2.9-2.93.0-2.9-3.0-3.03.02.93.0-2.83.0-2.9-3.1
Intermitt. access day 1 inactive lever presses0.20.20.8-0.10.3-0.3-0.20.2-0.4-0.40.40.30.5-0.5-0.50.5-0.5-0.50.4-0.4-0.4-0.40.40.40.4-0.40.6-0.9-0.8
Intermitt. access day 15 inactive lever presses0.60.60.80.6-0.50.50.50.8-0.8-0.90.90.80.8-0.8-0.80.8-0.8-0.80.8-0.8-0.8-0.80.80.80.8-0.90.9-0.9-0.8
Intermitt. access escalation Index0.50.41.1-0.0-0.10.10.2-0.40.60.6-0.6-0.6-0.60.60.6-0.60.60.6-0.70.70.70.7-0.7-0.7-0.70.8-0.91.11.0
Intermittent access day 1 total infusions0.00.10.1-0.10.2-0.2-0.2-0.20.20.4-0.4-0.2-0.20.20.2-0.20.20.2-0.20.20.20.2-0.2-0.2-0.20.1-0.20.30.3
Intermittent access day 15 total infusions2.12.32.91.1-1.01.01.01.5-1.6-1.61.61.51.6-1.6-1.61.6-1.6-1.61.6-1.6-1.6-1.61.61.61.6-1.61.7-1.6-1.6
Intermittent access terminal intake (last 3 days)0.91.01.31.0-0.80.80.81.1-1.1-1.11.11.01.1-1.1-1.11.1-1.1-1.11.1-1.0-1.0-1.11.11.01.0-1.01.2-0.9-1.0
Intermittent access total infusions0.20.20.40.3-0.20.20.20.5-0.5-0.50.50.50.5-0.5-0.50.5-0.5-0.50.5-0.5-0.5-0.50.50.50.5-0.50.6-0.6-0.5
Intermittent access day 1 locomotion0.50.50.60.5-0.50.50.50.7-0.8-0.70.70.60.8-0.8-0.80.8-0.8-0.80.7-0.7-0.7-0.60.60.70.7-0.70.8-0.7-0.6
Intermittent access day 15 total locomotion3.63.94.41.9-1.81.81.82.1-2.1-2.12.11.92.1-2.1-2.12.1-2.1-2.12.0-2.0-2.0-1.91.92.01.9-1.92.0-1.6-1.7
Intermittent access total locomotion0.80.91.21.1-1.01.01.01.1-1.1-1.01.00.91.0-1.0-1.01.0-1.0-1.01.0-1.0-1.0-0.90.90.90.9-0.91.0-0.7-0.7
Intermittent access standard deviation2.72.93.51.3-1.21.21.21.6-1.8-1.81.81.71.8-1.8-1.81.8-1.8-1.81.8-1.8-1.8-1.71.71.81.7-1.81.9-1.8-1.7
Left kidney weight0.00.10.30.3-0.50.50.50.2-0.1-0.10.10.0-0.00.00.0-0.00.00.0-0.00.00.10.0-0.0-0.0-0.00.1-0.20.40.4
Right kidney weight1.23.44.11.8-2.02.02.02.0-1.9-1.91.91.91.9-1.9-1.91.9-1.9-1.91.8-1.9-1.8-1.81.81.81.8-1.81.6-1.4-1.5
Cocaine induced anxiety0.40.41.61.2-1.31.31.30.8-0.5-0.40.40.50.4-0.4-0.40.4-0.4-0.40.4-0.4-0.4-0.40.40.40.4-0.40.10.50.3
Post-drug Anxiety0.40.41.61.3-1.31.31.30.8-0.5-0.50.50.60.5-0.5-0.50.5-0.5-0.50.5-0.5-0.5-0.50.50.50.4-0.50.20.40.2
Baseline Anxiety0.40.41.20.00.0-0.0-0.00.4-0.6-0.60.60.60.6-0.6-0.60.6-0.6-0.60.6-0.6-0.6-0.60.60.60.6-0.60.8-1.1-1.0
Tail length3.29.711.72.8-2.52.52.53.2-3.2-3.43.43.13.4-3.4-3.43.4-3.4-3.43.1-3.1-3.1-3.13.13.13.1-3.13.2-2.7-3.1
Length with tail1.76.17.52.7-2.72.72.72.7-2.5-2.62.62.52.6-2.6-2.62.6-2.6-2.62.4-2.4-2.4-2.42.42.42.4-2.42.3-1.6-1.9
Length without tail0.10.21.01.0-1.01.00.90.4-0.1-0.20.20.1-0.10.10.1-0.10.10.10.1-0.1-0.10.0-0.00.10.0-0.0-0.20.70.6
Times rat made contact with spout0.20.21.3-1.10.8-0.8-0.8-0.60.30.2-0.2-0.3-0.10.10.1-0.10.10.1-0.30.30.30.3-0.3-0.3-0.30.3-0.2-0.4-0.1
Lifetime Intake0.10.10.20.2-0.10.10.10.3-0.3-0.30.30.20.3-0.3-0.30.3-0.3-0.30.3-0.3-0.3-0.20.20.30.3-0.30.4-0.3-0.2
Liver weight, left2.03.24.0-1.92.0-2.0-2.0-1.91.81.7-1.7-1.9-1.81.81.8-1.81.81.8-1.81.81.81.8-1.8-1.8-1.81.8-1.61.11.3
Liver weight, right1.52.53.2-1.21.4-1.4-1.4-1.51.71.4-1.4-1.7-1.51.51.5-1.51.51.5-1.71.71.71.8-1.8-1.8-1.81.8-1.61.51.5
Locomotor activity2.53.97.92.7-2.82.82.82.3-1.9-1.91.92.11.8-1.8-1.81.8-1.8-1.81.8-1.8-1.9-2.02.01.91.9-1.91.5-0.5-1.0
Locomotor testing distance1.52.54.52.0-2.12.12.11.8-1.5-1.41.41.81.4-1.4-1.41.4-1.4-1.41.5-1.5-1.6-1.71.71.61.7-1.61.3-0.6-1.0
Locomotor testing rearing0.10.10.4-0.30.3-0.3-0.2-0.0-0.2-0.20.20.3-0.00.00.0-0.00.00.00.3-0.2-0.3-0.30.30.30.3-0.30.4-0.6-0.6
Locomotion in novel chamber0.20.20.5-0.2-0.30.20.30.3-0.5-0.50.50.50.4-0.4-0.40.4-0.4-0.40.5-0.5-0.5-0.60.60.50.5-0.60.3-0.7-0.5
Locomotion in novel chamber post-restriction1.21.41.90.8-0.70.60.71.1-1.2-1.41.41.21.3-1.3-1.31.3-1.3-1.31.2-1.2-1.1-1.21.21.21.2-1.21.2-1.3-1.3
Fecal boli incidents, locomotor time 11.71.82.6-1.41.5-1.3-1.2-1.41.41.2-1.2-1.5-1.11.11.1-1.11.11.1-1.51.51.51.6-1.6-1.6-1.61.6-1.30.91.2
Change in fecal boli incidents, locomotor task0.00.00.20.4-0.20.10.20.3-0.2-0.40.40.10.2-0.2-0.20.2-0.2-0.20.1-0.1-0.1-0.10.10.10.1-0.20.10.0-0.1
Time >=10cm from walls, locomotor time 11.21.22.5-0.50.3-0.2-0.4-0.81.11.2-1.2-1.1-1.11.11.1-1.11.11.1-1.21.11.21.2-1.2-1.2-1.21.3-1.41.61.5
Bouts of movement, locomotor time 10.30.30.90.3-0.20.20.10.5-0.5-0.90.90.30.7-0.7-0.70.7-0.7-0.70.4-0.5-0.4-0.30.30.40.4-0.30.5-0.6-0.6
Total resting periods, locomotor time 10.30.30.90.5-0.30.40.30.6-0.6-0.90.90.30.8-0.8-0.80.8-0.8-0.80.5-0.5-0.5-0.30.30.40.4-0.40.5-0.6-0.6
Rest time, locomotor task time 10.40.51.31.0-0.60.70.40.8-0.6-1.21.20.20.9-0.9-0.90.9-0.9-0.90.4-0.5-0.4-0.20.20.40.3-0.30.4-0.3-0.4
Distance moved, locomotor task time 11.11.22.2-0.60.5-0.5-0.4-0.91.11.5-1.5-0.9-1.21.21.2-1.21.21.2-1.01.11.00.9-0.9-1.0-1.01.0-1.31.51.4
Vertical activity count, locomotor time 10.30.41.5-1.20.8-0.9-0.7-0.80.51.0-1.0-0.2-0.60.60.6-0.60.60.6-0.30.30.30.2-0.2-0.3-0.20.2-0.2-0.10.0
Time >=10cm from walls, locomotor time 21.61.72.7-1.61.5-1.5-1.5-1.51.41.2-1.2-1.3-1.21.21.2-1.21.21.2-1.41.31.31.3-1.3-1.3-1.21.3-1.20.70.9
Bouts of movement, locomotor time 20.50.52.01.1-1.41.31.40.9-0.6-0.50.50.70.5-0.5-0.50.5-0.5-0.50.5-0.6-0.6-0.60.60.60.6-0.60.30.30.1
Total resting periods, locomotor time 20.50.51.91.1-1.41.31.40.9-0.5-0.40.40.70.4-0.4-0.40.4-0.4-0.40.5-0.5-0.5-0.60.60.60.6-0.60.20.40.1
Rest time, locomotor task time 20.50.51.21.0-1.11.11.10.9-0.7-0.80.80.70.7-0.7-0.70.7-0.7-0.70.6-0.7-0.7-0.70.70.70.7-0.60.4-0.1-0.2
Distance moved, locomotor task time 20.60.71.4-0.91.1-1.2-1.2-1.00.90.8-0.8-0.8-0.80.80.8-0.80.80.8-0.80.80.80.8-0.8-0.8-0.80.8-0.60.30.5
Vertical activity count, locomotor time 20.60.62.0-1.21.4-1.4-1.4-1.00.80.8-0.8-0.8-0.50.50.5-0.50.50.5-0.70.70.70.7-0.7-0.7-0.70.7-0.4-0.20.1
Light reinforcement 15.510.013.93.7-3.73.73.73.6-3.3-3.03.03.33.0-3.0-3.03.0-3.0-3.03.2-3.1-3.2-3.23.23.23.1-3.12.9-1.7-2.2
Light reinforcement 21.92.54.12.0-1.91.92.01.8-1.6-1.41.41.61.5-1.5-1.51.5-1.5-1.51.6-1.5-1.6-1.61.61.61.5-1.61.5-0.7-1.0
Bone: marrow area0.20.40.6-0.40.4-0.4-0.5-0.50.60.4-0.4-0.7-0.60.60.6-0.60.60.6-0.70.60.70.7-0.7-0.7-0.70.7-0.80.50.6
Bone: maximum diameter0.50.92.71.6-1.61.51.51.2-0.9-1.01.00.90.8-0.8-0.80.8-0.8-0.80.8-0.8-0.8-0.80.80.80.8-0.80.60.0-0.3
Bone: maximum force1.32.32.8-1.21.2-1.2-1.3-1.51.61.3-1.3-1.6-1.61.61.6-1.61.61.6-1.71.61.61.6-1.6-1.6-1.61.6-1.61.31.3
Bone: maximum moment1.11.82.2-1.21.1-1.1-1.1-1.41.41.3-1.3-1.4-1.41.41.4-1.41.41.4-1.51.41.51.4-1.4-1.4-1.41.4-1.51.11.2
Mean time between licks in bursts4.15.86.62.2-2.22.22.22.4-2.5-2.52.52.62.3-2.3-2.32.3-2.3-2.32.5-2.5-2.5-2.62.62.62.6-2.62.5-2.1-2.4
Mean num. licks in bursts0.00.00.2-0.10.2-0.2-0.1-0.10.20.2-0.2-0.3-0.00.00.0-0.00.00.0-0.20.30.30.3-0.3-0.3-0.30.3-0.20.30.4
Cd content in liver0.40.40.8-0.50.3-0.3-0.3-0.60.70.7-0.7-0.5-0.90.90.9-0.90.90.9-0.60.60.50.5-0.5-0.5-0.50.5-0.70.70.6
Co content in liver0.60.70.90.9-0.70.70.70.8-0.8-0.90.90.90.8-0.8-0.80.8-0.8-0.80.8-0.8-0.8-0.90.90.80.9-0.90.9-0.7-0.9
Cu content in liver0.30.31.30.3-0.20.20.2-0.20.60.4-0.4-0.5-0.50.50.5-0.50.50.5-0.60.60.60.6-0.6-0.6-0.60.6-0.81.10.9
Fe content in liver0.20.20.60.60.1-0.1-0.10.3-0.4-0.80.80.20.7-0.7-0.70.7-0.7-0.70.3-0.3-0.3-0.30.30.30.3-0.30.5-0.6-0.7
K content in liver0.20.21.21.1-0.60.60.60.20.2-0.30.3-0.2-0.20.20.2-0.20.20.2-0.40.40.40.3-0.3-0.3-0.30.3-0.51.00.7
Mg content in liver0.20.21.20.9-0.60.60.60.10.3-0.10.1-0.2-0.40.40.4-0.40.40.4-0.40.40.50.4-0.4-0.4-0.40.4-0.61.10.8
Mn content in liver0.91.05.52.3-1.91.91.91.3-0.7-1.01.00.60.9-0.9-0.90.9-0.9-0.90.4-0.5-0.5-0.50.50.50.4-0.50.20.80.3
Na content in liver1.01.12.90.40.3-0.3-0.3-0.71.10.7-0.7-1.1-1.01.01.0-1.01.01.0-1.21.31.21.2-1.2-1.2-1.21.2-1.21.71.4
Rb content in liver0.60.82.20.1-0.00.00.0-0.50.90.8-0.8-0.8-0.90.90.9-0.90.90.9-1.01.01.00.9-0.9-1.0-0.90.9-1.11.51.3
Se content in liver0.40.41.11.1-0.60.60.60.7-0.6-1.01.00.40.9-0.9-0.90.9-0.9-0.90.4-0.4-0.4-0.40.40.40.4-0.40.5-0.2-0.4
Sr content in liver0.10.10.7-0.40.4-0.4-0.4-0.0-0.2-0.20.20.20.3-0.3-0.30.3-0.3-0.30.4-0.3-0.4-0.30.30.30.3-0.30.5-0.8-0.7
Zn content in liver2.22.55.30.3-0.50.50.51.2-1.6-1.51.51.61.5-1.5-1.51.5-1.5-1.51.7-1.8-1.7-1.81.81.81.8-1.82.0-2.3-2.1
Bone: minimum diameter0.00.00.20.4-0.20.20.10.00.1-0.20.2-0.2-0.10.10.1-0.10.10.1-0.20.20.20.3-0.3-0.2-0.20.2-0.30.40.2
Time in familiar zone, hab. session 12.92.73.71.0-1.11.11.11.5-1.6-1.51.51.61.9-1.9-1.91.9-1.9-1.91.7-1.7-1.7-1.71.71.71.7-1.71.8-1.7-1.8
Time in novel zone, hab. session 11.71.62.5-0.60.6-0.6-0.6-1.01.21.2-1.2-1.2-1.51.51.5-1.51.51.5-1.31.31.31.3-1.3-1.3-1.31.3-1.51.51.6
Total zone transitions, hab. session 10.81.24.02.0-1.91.91.91.4-0.9-1.01.01.00.8-0.8-0.80.8-0.8-0.80.8-0.8-0.8-0.80.80.80.8-0.80.40.50.2
Total locomotion distance, hab. session 11.11.56.62.6-2.22.22.21.6-0.9-1.21.20.91.0-1.0-1.01.0-1.0-1.00.7-0.8-0.7-0.70.70.70.7-0.70.30.80.4
Locomotion velocity, hab. session 11.52.27.62.8-2.42.42.41.8-1.2-1.51.51.21.3-1.3-1.31.3-1.3-1.31.1-1.1-1.0-1.01.01.01.0-1.00.60.50.1
Time in familiar zone, hab. session 26.97.18.71.6-1.92.02.02.6-2.8-2.62.62.72.8-2.8-2.82.8-2.8-2.82.8-2.9-2.8-2.82.82.82.8-2.82.9-2.8-2.8
Time in novel zone, hab. session 25.45.46.9-1.81.7-1.7-1.7-2.32.42.3-2.3-2.3-2.52.52.5-2.52.52.5-2.42.42.42.4-2.4-2.4-2.42.4-2.62.42.5
Total zone transitions, hab. session 20.70.94.80.8-1.00.91.0-0.00.70.6-0.6-0.5-0.90.90.9-0.90.90.9-0.80.80.70.7-0.7-0.7-0.70.7-1.42.21.9
Total locomotion distance, hab. session 20.91.24.11.9-2.02.02.01.4-0.9-0.90.91.00.7-0.7-0.70.7-0.7-0.70.8-0.9-0.8-0.80.80.80.8-0.80.30.60.3
Locomotion velocity, hab. session 20.91.24.92.0-2.22.22.21.5-0.8-0.80.80.90.6-0.6-0.60.6-0.6-0.60.7-0.7-0.7-0.70.70.70.7-0.70.11.00.6
Novel to familiar place preference ratio5.25.37.3-1.41.5-1.5-1.5-2.12.42.4-2.4-2.4-2.42.42.4-2.42.42.4-2.42.42.42.4-2.4-2.4-2.42.4-2.62.62.7
Novelty place preference3.33.35.0-1.01.0-1.1-1.1-1.61.91.9-1.9-1.9-1.91.91.9-1.91.91.9-1.91.91.91.9-1.9-1.9-1.91.9-2.12.22.2
Time in novel zone, NPP test3.53.65.0-1.21.2-1.3-1.3-1.72.01.9-1.9-2.0-1.91.91.9-1.91.91.9-2.02.02.02.0-2.0-2.0-2.02.0-2.12.22.2
Total zone transitions, NPP test0.20.42.00.9-1.01.01.00.20.20.3-0.3-0.1-0.30.30.3-0.30.30.3-0.30.30.20.2-0.2-0.2-0.20.2-0.71.41.2
Total locomotion distance, NPP test0.30.42.01.1-0.80.80.80.20.30.2-0.2-0.2-0.30.30.3-0.30.30.3-0.40.40.40.4-0.4-0.4-0.40.4-0.71.41.2
Locomotion velocity, NPP test0.20.31.61.2-1.11.11.10.50.0-0.00.00.0-0.10.10.1-0.10.10.1-0.10.10.10.1-0.1-0.1-0.10.1-0.51.31.0
Intraocular pressure0.30.41.9-1.10.7-0.7-0.7-0.2-0.30.0-0.00.30.4-0.4-0.40.4-0.4-0.40.5-0.5-0.5-0.50.50.50.5-0.50.8-1.4-1.0
Delta distance traveled before/after self-admin1.82.02.21.5-1.31.31.31.5-1.4-1.51.51.51.5-1.5-1.51.5-1.5-1.51.4-1.3-1.4-1.51.51.31.4-1.31.3-1.0-1.2
Delta ambulatory time before/after self-admin1.92.12.71.7-1.51.41.51.6-1.5-1.61.61.51.5-1.5-1.51.5-1.5-1.51.4-1.4-1.4-1.41.41.41.4-1.41.3-0.9-1.1
Parametrial fat weight0.40.81.10.5-0.40.40.40.8-0.9-0.90.90.81.1-1.1-1.11.1-1.1-1.10.9-0.9-0.8-0.90.90.80.8-0.81.0-1.0-1.0
Pavlov. Cond. lever latency0.10.21.4-1.20.5-0.5-0.5-0.3-0.10.3-0.30.2-0.10.10.1-0.10.10.10.3-0.2-0.3-0.30.30.30.3-0.30.4-0.9-0.7
Pavlov. Cond. magazine entry latency3.74.86.42.4-1.91.91.92.4-2.3-2.52.52.12.4-2.4-2.42.4-2.4-2.42.1-2.2-2.1-2.12.12.12.1-2.12.2-1.7-1.9
Pavlov. Cond. change in total contacts0.20.20.91.0-0.40.40.40.5-0.3-0.80.80.20.6-0.6-0.60.6-0.6-0.60.3-0.3-0.2-0.20.20.20.2-0.20.3-0.1-0.2
Pavlov. Cond. index score0.70.93.21.8-1.11.11.11.2-0.8-1.31.30.71.1-1.1-1.11.1-1.1-1.10.6-0.7-0.6-0.60.60.60.6-0.60.6-0.1-0.3
Pavlov. Cond. latency score0.70.83.92.0-1.21.21.21.2-0.7-1.21.20.61.0-1.0-1.01.0-1.0-1.00.5-0.6-0.5-0.50.50.50.5-0.50.40.2-0.1
Pavlov. Cond. lever contacts0.20.32.01.4-0.80.80.80.5-0.1-0.50.5-0.00.3-0.3-0.30.3-0.3-0.3-0.10.10.10.1-0.1-0.1-0.10.1-0.30.90.6
Pavlov. Cond. magazine entry number1.11.32.4-1.61.0-0.9-1.1-1.31.21.4-1.4-1.0-1.31.31.3-1.31.31.3-1.11.11.01.0-1.0-1.0-1.01.0-1.10.80.9
Pavlov. Cond. intertrial magazine entries0.20.20.9-0.30.0-0.10.00.2-0.5-0.30.30.50.3-0.3-0.30.3-0.3-0.30.6-0.5-0.6-0.60.60.60.6-0.60.6-1.0-0.8
Pavlov. Cond. lever-magazine prob. diff.1.11.43.81.9-1.31.31.31.4-1.1-1.51.50.91.3-1.3-1.31.3-1.3-1.30.9-1.0-0.9-0.90.90.90.9-0.90.9-0.3-0.6
Pavlov. Cond. response bias1.61.93.31.8-1.31.21.31.5-1.4-1.71.71.21.5-1.5-1.51.5-1.5-1.51.2-1.3-1.2-1.21.21.21.2-1.21.3-0.9-1.1
Pavlov. Cond. lever latency0.50.71.0-0.70.7-0.7-0.7-0.80.90.8-0.8-1.0-0.80.80.8-0.80.80.8-0.90.90.91.0-1.0-0.9-1.00.9-0.90.91.0
Pavlov. Cond. magazine entry latency0.40.50.70.7-0.50.50.50.7-0.7-0.90.90.60.8-0.8-0.80.8-0.8-0.80.6-0.7-0.6-0.60.60.60.6-0.60.7-0.6-0.7
Pavlov. Cond. change in total contacts0.50.71.10.4-0.70.70.70.7-0.9-0.70.71.00.7-0.7-0.70.7-0.7-0.71.0-0.9-1.0-1.11.11.11.1-1.11.0-0.9-1.0
Pavlov. Cond. index score0.70.91.20.7-0.60.60.60.8-1.0-1.01.01.01.0-1.0-1.01.0-1.0-1.01.0-1.0-1.0-1.01.01.01.0-1.01.0-1.0-1.1
Pavlov. Cond. latency score0.60.70.90.7-0.70.70.70.8-0.9-0.80.80.90.8-0.8-0.80.8-0.8-0.80.9-0.9-0.9-0.90.90.90.9-0.90.9-0.8-0.9
Pavlov. Cond. lever contacts0.60.81.40.5-0.50.50.50.7-0.9-0.90.91.00.9-0.9-0.90.9-0.9-0.91.0-1.0-1.0-1.01.01.01.0-1.01.1-1.2-1.2
Pavlov. Cond. magazine entry number0.70.91.2-1.00.7-0.7-0.7-0.90.91.1-1.1-0.9-1.01.01.0-1.01.01.0-0.90.90.90.9-0.9-0.9-0.90.9-1.00.81.0
Pavlov. Cond. intertrial magazine entries0.20.31.0-1.01.0-1.0-0.9-0.70.50.4-0.4-0.5-0.60.60.6-0.60.60.6-0.40.40.40.4-0.4-0.4-0.40.4-0.3-0.20.0
Pavlov. Cond. lever-magazine prob. diff.0.70.91.00.8-0.70.70.70.9-0.9-1.01.01.01.0-1.0-1.01.0-1.0-1.00.9-0.9-1.0-1.01.01.01.0-1.01.0-0.9-1.0
Pavlov. Cond. response bias1.62.23.00.9-1.01.01.01.3-1.5-1.51.51.61.5-1.5-1.51.5-1.5-1.51.6-1.6-1.6-1.61.61.61.6-1.61.7-1.7-1.7
Time in closed arm before self-admin1.01.13.0-0.0-0.00.0-0.0-0.71.01.0-1.0-1.1-1.01.01.0-1.01.01.0-1.11.11.11.2-1.2-1.1-1.11.1-1.31.71.6
Time in closed arm after self-admin0.00.00.10.0-0.00.0-0.00.1-0.2-0.20.20.10.2-0.2-0.20.2-0.2-0.20.2-0.2-0.2-0.20.20.20.2-0.20.2-0.3-0.3
Time in open arm before self-admin0.60.71.10.6-0.50.50.50.8-0.9-1.01.00.80.8-0.8-0.80.8-0.8-0.80.9-0.9-0.9-0.80.80.90.8-0.90.9-0.9-1.0
Time in open arm after self-admin0.70.81.1-1.10.9-0.9-0.9-1.00.91.0-1.0-0.9-1.01.01.0-1.01.01.0-0.90.90.90.9-0.9-0.8-0.80.8-0.80.60.7
Bone: periosteal estimation0.40.81.4-0.20.2-0.2-0.3-0.70.90.7-0.7-0.9-1.01.01.0-1.01.01.0-1.01.01.01.0-1.0-1.0-1.01.0-1.11.21.1
Bone: periosteal perimeter0.10.10.60.8-0.70.70.60.3-0.0-0.20.20.10.0-0.0-0.00.0-0.0-0.0-0.1-0.00.00.0-0.0-0.00.00.0-0.10.60.3
Bone: post-yield work0.40.51.1-0.71.0-1.0-1.0-0.80.80.3-0.3-0.8-0.60.60.6-0.60.60.6-0.80.80.80.8-0.8-0.8-0.80.8-0.60.20.2
Progressive ratio test 1 active lever presses0.10.10.3-0.50.5-0.5-0.5-0.20.1-0.00.0-0.2-0.00.00.0-0.00.00.0-0.00.10.10.1-0.1-0.1-0.10.10.1-0.4-0.1
Progressive ratio test 1 breakpoint0.10.10.4-0.60.6-0.6-0.6-0.30.20.0-0.0-0.3-0.10.10.1-0.10.10.1-0.20.20.20.2-0.2-0.2-0.20.2-0.0-0.30.1
Progressive ratio test 1 inactive lever presses0.00.00.10.1-0.20.20.10.2-0.2-0.20.20.00.2-0.2-0.20.2-0.2-0.20.2-0.2-0.1-0.00.00.10.1-0.00.2-0.20.0
Progressive ratio test 2 active lever presses0.20.20.7-0.00.1-0.1-0.10.3-0.5-0.50.50.30.5-0.5-0.50.5-0.5-0.50.5-0.5-0.5-0.30.30.40.4-0.40.7-0.8-0.7
Progressive ratio test 2 breakpoint0.20.20.40.3-0.20.20.20.4-0.5-0.50.50.30.5-0.5-0.50.5-0.5-0.50.5-0.5-0.5-0.30.30.40.4-0.40.6-0.6-0.5
Progressive ratio test 2 inactive lever presses0.00.00.20.4-0.20.20.20.2-0.1-0.10.10.00.1-0.1-0.10.1-0.1-0.10.1-0.1-0.10.0-0.00.10.0-0.00.10.10.1
Incentive Sensitization - Responses0.10.10.5-0.10.2-0.2-0.20.2-0.3-0.30.30.20.4-0.4-0.40.4-0.4-0.40.4-0.3-0.3-0.20.20.30.2-0.30.5-0.7-0.7
Incentive Sensitization - Breakpoint0.20.20.50.00.1-0.1-0.10.3-0.4-0.40.40.20.5-0.5-0.50.5-0.5-0.50.4-0.4-0.4-0.30.30.40.3-0.30.6-0.7-0.7
Sum of active levers in priming session hrs 5-60.00.00.00.1-0.1-0.00.00.00.10.2-0.2-0.1-0.10.10.1-0.10.10.1-0.10.10.10.1-0.1-0.1-0.10.1-0.10.20.2
Progressive ratio0.10.10.2-0.20.3-0.4-0.4-0.30.30.1-0.1-0.4-0.10.10.1-0.10.10.1-0.30.20.30.4-0.4-0.3-0.30.3-0.20.10.2
Food seeking constrained by brief footshock0.30.41.21.1-0.90.90.70.8-0.6-0.80.80.40.8-0.8-0.80.8-0.8-0.80.5-0.5-0.4-0.30.30.40.4-0.40.40.0-0.3
Seeking ratio, punishment vs. effort0.20.20.60.8-0.70.70.70.6-0.5-0.40.40.40.5-0.5-0.50.5-0.5-0.50.3-0.3-0.4-0.40.40.40.4-0.40.20.1-0.2
Retroperitoneal fat weight0.20.61.0-0.91.0-1.0-1.0-0.80.70.7-0.7-0.8-0.70.70.7-0.70.70.7-0.80.70.80.8-0.8-0.8-0.80.9-0.60.30.5
Reaction time number correct0.40.63.0-1.71.7-1.7-1.7-1.00.50.4-0.4-0.6-0.40.40.4-0.40.40.4-0.40.40.40.5-0.5-0.4-0.40.4-0.1-0.8-0.4
Reaction time mean minus median0.60.91.10.6-0.70.70.60.8-0.9-1.01.01.00.9-0.9-0.90.9-0.9-0.91.0-1.0-1.0-1.01.01.01.0-1.01.1-1.1-1.1
Reaction time mean minus median AUC0.00.10.30.4-0.40.40.30.10.10.0-0.0-0.1-0.10.10.1-0.10.10.1-0.20.10.20.2-0.2-0.2-0.20.2-0.30.50.4
Reaction time num false alarms0.20.21.2-0.71.1-1.1-1.1-0.50.2-0.00.0-0.2-0.10.10.1-0.10.10.1-0.10.10.10.1-0.1-0.1-0.10.10.3-0.7-0.6
Reaction time num false alarms AUC0.20.31.6-0.91.3-1.3-1.3-0.60.3-0.00.0-0.3-0.10.10.1-0.10.10.1-0.20.20.10.1-0.1-0.1-0.10.10.3-0.9-0.7
Reaction time trials correct on left0.40.63.0-1.71.7-1.7-1.7-1.00.50.4-0.4-0.6-0.40.40.4-0.40.40.4-0.40.40.40.5-0.5-0.4-0.40.4-0.1-0.8-0.4
Reaction time trials on left0.50.63.0-1.71.6-1.6-1.7-1.00.60.4-0.4-0.7-0.40.40.4-0.40.40.4-0.40.50.40.5-0.5-0.5-0.50.5-0.2-0.7-0.3
Reaction time mean0.10.10.2-0.2-0.10.10.1-0.20.20.3-0.3-0.2-0.40.40.4-0.40.40.4-0.20.30.20.2-0.2-0.2-0.20.2-0.30.40.4
Reaction time mean AUC0.10.10.3-0.2-0.00.00.0-0.30.40.5-0.5-0.3-0.50.50.5-0.50.50.5-0.30.30.30.3-0.3-0.3-0.30.3-0.40.50.5
Median of all reaction times0.40.60.9-0.50.3-0.3-0.3-0.70.80.9-0.9-0.7-0.90.90.9-0.90.90.9-0.80.80.70.7-0.7-0.7-0.70.7-0.90.90.9
Reaction time omissions0.10.20.70.3-0.80.80.80.5-0.5-0.10.10.50.2-0.2-0.20.2-0.2-0.20.5-0.5-0.5-0.40.40.50.4-0.40.2-0.1-0.0
Reaction time false alarm rate0.00.00.10.10.4-0.4-0.4-0.20.20.0-0.0-0.2-0.10.10.1-0.10.10.1-0.20.20.10.1-0.1-0.1-0.10.10.1-0.0-0.1
Reaction time premature initiation rate1.11.52.10.5-0.80.80.91.1-1.3-1.11.11.41.1-1.1-1.11.1-1.1-1.11.4-1.4-1.4-1.41.41.41.4-1.41.4-1.4-1.4
Reaction time premature initiations0.91.34.0-0.4-0.00.00.00.6-1.1-1.01.01.21.0-1.0-1.01.0-1.0-1.01.3-1.3-1.3-1.31.31.31.3-1.31.4-2.0-1.7
Std. dev. reaction times0.10.20.20.3-0.40.40.40.3-0.4-0.40.40.50.3-0.3-0.30.3-0.3-0.30.4-0.5-0.5-0.50.50.50.5-0.40.4-0.4-0.4
Reaction time trials completed0.50.63.0-1.71.6-1.6-1.7-1.00.60.4-0.4-0.7-0.40.40.4-0.40.40.4-0.40.50.40.5-0.5-0.5-0.50.5-0.2-0.7-0.3
Reaction time trials AUC0.50.73.3-1.81.7-1.7-1.7-1.00.50.3-0.3-0.6-0.30.30.3-0.30.30.3-0.30.40.30.4-0.4-0.4-0.40.4-0.0-1.0-0.5
Run reversals in cocaine runway, females0.40.40.60.7-0.70.80.60.7-0.6-0.70.70.50.7-0.7-0.70.7-0.7-0.70.6-0.7-0.6-0.50.50.60.6-0.60.5-0.3-0.5
Run reversals in cocaine runway, males1.51.42.21.4-1.51.51.51.4-1.3-1.11.11.21.2-1.2-1.21.2-1.2-1.21.2-1.2-1.2-1.21.21.21.2-1.21.1-0.6-0.7
Latency to leave start box in cocaine runway0.40.42.21.2-1.41.31.50.7-0.5-0.20.20.70.1-0.1-0.10.1-0.1-0.10.4-0.4-0.5-0.60.60.50.5-0.50.10.50.3
Latency to leave start box in cocaine runway, F0.80.83.20.4-0.70.60.8-0.30.71.0-1.0-0.4-1.01.01.0-1.01.01.0-0.70.80.70.6-0.6-0.7-0.60.6-1.21.81.6
Latency to leave start box in cocaine runway, M3.33.14.21.1-1.01.01.01.6-1.8-2.02.01.71.9-1.9-1.91.9-1.9-1.91.8-1.8-1.9-1.81.81.91.8-1.91.9-2.1-2.0
Std. dev. time between licks in bursts0.50.61.01.0-1.01.00.90.9-0.8-0.90.90.80.6-0.6-0.60.6-0.6-0.60.8-0.7-0.8-0.80.80.80.8-0.80.6-0.4-0.6
Total sessions with >9 infusions0.10.10.3-0.00.0-0.0-0.1-0.10.30.2-0.2-0.4-0.30.30.3-0.30.30.3-0.30.30.30.4-0.4-0.3-0.40.3-0.30.50.5
Short access day 1 total inactive lever presses0.10.10.10.4-0.30.30.30.4-0.3-0.30.30.20.3-0.3-0.30.3-0.3-0.30.2-0.2-0.2-0.10.10.20.2-0.20.2-0.10.1
Short access day 10 total inactive lever presses0.00.00.0-0.20.2-0.2-0.2-0.10.00.0-0.00.1-0.00.00.0-0.00.00.00.0-0.1-0.1-0.20.20.10.1-0.20.1-0.1-0.2
Short access day 1 total infusions0.10.10.80.9-0.80.80.70.6-0.3-0.30.30.20.2-0.2-0.20.2-0.2-0.20.2-0.2-0.2-0.10.10.20.1-0.10.10.40.3
Short access day 10 total infusions0.10.10.4-0.10.2-0.2-0.20.2-0.3-0.40.40.10.4-0.4-0.40.4-0.4-0.40.3-0.3-0.3-0.20.20.30.2-0.30.5-0.6-0.3
Short access total infusions0.00.00.00.1-0.00.0-0.00.00.00.0-0.0-0.2-0.10.10.1-0.10.10.1-0.10.10.10.2-0.2-0.1-0.10.1-0.00.20.2
Short access day 1 locomotion0.70.81.41.2-1.21.21.11.1-0.9-0.90.90.80.9-0.9-0.90.9-0.9-0.90.8-0.8-0.8-0.70.70.80.7-0.80.8-0.3-0.3
Short access day 10 total locomotion3.74.14.71.8-1.71.71.62.0-2.2-2.22.21.92.1-2.1-2.12.1-2.1-2.12.1-2.1-2.1-2.02.02.12.0-2.12.1-1.9-1.9
Short access total locomotion0.60.71.01.0-0.90.90.80.9-0.9-0.90.90.70.8-0.8-0.80.8-0.8-0.80.8-0.8-0.8-0.70.70.80.7-0.80.9-0.5-0.6
One hour access (0.3 mA shock)0.10.10.3-0.30.5-0.5-0.5-0.40.30.3-0.3-0.5-0.30.30.3-0.30.30.3-0.30.30.40.5-0.5-0.3-0.40.2-0.20.10.4
Compulsive drug intake1.61.62.1-0.80.8-0.8-0.8-1.21.31.3-1.3-1.3-1.41.41.4-1.41.41.4-1.41.31.31.4-1.4-1.3-1.31.2-1.41.51.3
One hour access (shock baseline)0.20.31.0-0.00.2-0.2-0.20.3-0.5-0.60.60.30.6-0.6-0.60.6-0.6-0.60.5-0.5-0.5-0.40.40.50.4-0.50.8-1.0-0.6
Social response proportion0.60.72.11.2-1.41.41.41.0-0.7-0.70.70.80.6-0.6-0.60.6-0.6-0.60.7-0.7-0.7-0.70.70.70.7-0.70.40.1-0.1
Social responses5.97.610.83.3-3.33.33.33.1-2.8-2.82.82.92.6-2.6-2.62.6-2.6-2.62.7-2.7-2.7-2.82.82.82.8-2.82.4-1.5-2.0
Social time0.70.91.3-0.70.5-0.5-0.5-0.90.91.1-1.1-0.9-1.11.11.1-1.11.11.1-1.01.00.90.9-0.9-0.9-0.90.9-1.01.11.0
Soleus weight8.925.929.6-5.25.2-5.2-5.3-5.45.35.1-5.1-5.3-5.25.25.2-5.25.25.2-5.25.25.25.2-5.2-5.2-5.25.2-4.73.64.0
Bone: stiffness3.04.75.7-1.61.9-1.9-2.0-2.12.21.8-1.8-2.3-2.32.32.3-2.32.32.3-2.42.32.42.3-2.3-2.3-2.32.3-2.11.81.8
Tibialis anterior weight1.13.74.7-1.82.1-2.1-2.2-2.02.01.6-1.6-2.1-1.91.91.9-1.91.91.9-2.02.02.12.1-2.1-2.1-2.12.1-1.71.31.4
Time to tail flick, vehicle, before self-admin0.40.41.51.1-1.21.21.20.8-0.5-0.30.30.60.4-0.4-0.40.4-0.4-0.40.4-0.5-0.5-0.50.50.50.5-0.50.20.30.1
Time to tail flick, vehicle, after self-admin0.50.51.5-0.00.1-0.1-0.20.3-0.6-0.70.70.70.6-0.6-0.60.6-0.6-0.60.7-0.7-0.7-0.80.80.70.8-0.71.0-1.2-1.2
Time to tail flick, test, before self-admin0.20.20.90.8-1.00.90.90.5-0.2-0.10.10.20.1-0.1-0.10.1-0.1-0.10.2-0.2-0.2-0.10.10.20.2-0.2-0.00.50.4
Time to tail flick, test, after self-admin0.40.40.90.8-0.91.00.90.7-0.5-0.70.70.70.5-0.5-0.50.5-0.5-0.50.5-0.6-0.6-0.70.70.60.7-0.70.4-0.1-0.2
Delta time to tail flick, vehicle, before/after SA0.30.31.7-1.01.3-1.3-1.3-0.60.3-0.00.0-0.3-0.20.20.2-0.20.20.2-0.20.20.20.2-0.2-0.2-0.20.20.2-0.8-0.7
Delta time to tail flick, test, before/after SA0.50.41.00.20.00.00.10.4-0.6-0.80.80.60.7-0.7-0.70.7-0.7-0.70.6-0.6-0.6-0.70.70.60.7-0.60.8-1.0-0.9
Tibia length0.92.42.91.3-1.51.51.41.6-1.6-1.61.61.71.5-1.5-1.51.5-1.5-1.51.6-1.6-1.7-1.71.71.71.7-1.71.5-1.3-1.5
Ambulatory time before self-admin0.70.71.0-0.60.5-0.5-0.5-0.70.81.0-1.0-0.8-0.90.90.9-0.90.90.9-0.80.80.80.9-0.9-0.8-0.80.8-0.90.91.0
Ambulatory time after self-admin0.20.20.50.6-0.70.60.60.6-0.5-0.40.40.40.5-0.5-0.50.5-0.5-0.50.4-0.4-0.4-0.40.40.40.4-0.40.3-0.1-0.1
Bone: tissue strength2.01.92.4-1.10.9-0.9-1.0-1.41.51.5-1.5-1.3-1.61.61.6-1.61.61.6-1.41.41.41.4-1.4-1.4-1.41.4-1.41.41.3
Total heroin consumption1.92.22.61.5-1.61.61.51.6-1.6-1.41.41.61.5-1.5-1.51.5-1.5-1.51.5-1.6-1.5-1.51.51.51.5-1.51.4-1.0-1.3
Bone: trabecular number0.50.72.91.7-1.61.61.51.1-0.7-0.60.60.70.7-0.7-0.70.7-0.7-0.70.6-0.6-0.6-0.60.60.60.6-0.60.40.50.1
Bone: trabecular spacing0.50.73.6-1.91.8-1.8-1.8-0.90.30.1-0.1-0.3-0.20.20.2-0.20.20.2-0.10.10.10.1-0.1-0.1-0.10.10.2-1.4-0.9
Bone: trabecular thickness1.11.37.01.2-1.41.41.4-0.00.81.1-1.1-0.5-0.90.90.9-0.90.90.9-0.90.90.80.7-0.7-0.8-0.70.8-1.42.62.0
Bone: trabecular tissue density1.21.82.4-1.61.5-1.5-1.5-1.51.41.1-1.1-1.4-1.31.31.3-1.31.31.3-1.41.31.41.4-1.4-1.4-1.31.4-1.30.70.9
Water consumed over 24 hours0.70.81.5-0.70.5-0.5-0.5-0.91.00.9-0.9-0.9-0.90.90.9-0.90.90.9-1.01.01.01.0-1.0-1.0-1.01.0-1.21.11.2
Number of responses in last shaping day0.10.10.20.4-0.20.20.20.4-0.4-0.30.30.10.4-0.4-0.40.4-0.4-0.40.3-0.3-0.3-0.10.10.30.2-0.20.4-0.3-0.2