Hub : Genes

Aars2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio XM_006244513.5 0.04 0.03 4.9e-04 0.05 0.04 0.03 0.04 2.9e-05 1.9e-04 5.6e-04 5.3e-05
2 Brain alternative polyA XM_006244515.5 0.03 0.02 1.5e-03 0.01 0.02 0.02 0.02 3.6e-02 5.5e-03 8.2e-03 9.0e-03
3 Brain alternative polyA NM_001106891.1 0.04 0.02 1.2e-03 0.01 0.02 0.02 0.02 2.9e-02 4.3e-03 8.3e-03 8.1e-03
4 PL intron excision ratio chr9_22983699_22984236 0.03 0.02 1.3e-03 0.02 0.02 0.01 0.02 1.4e-03 6.9e-03 3.3e-02 6.7e-03
5 PL intron excision ratio chr9_22983930_22984236 0.03 0.02 1.5e-03 0.02 0.02 0.01 0.02 1.3e-03 4.6e-03 2.4e-02 4.6e-03
6 PL isoform ratio XM_006244513.5 0.05 0.03 1.0e-04 0.04 0.03 0.04 0.03 6.1e-05 5.2e-04 6.7e-05 1.4e-04
7 Liver isoform ratio XM_006244515.5 0.03 0.02 1.5e-03 0.01 0.02 0.01 0.01 6.3e-02 1.2e-03 1.0e-02 8.7e-03
8 PL gene expression Aars2 0.07 0.04 2.0e-05 0.03 0.04 0.04 0.04 9.0e-04 5.4e-05 6.7e-05 6.2e-05
9 Brain mRNA stability Aars2 0.09 0.05 2.3e-06 0.06 0.07 0.06 0.06 1.7e-06 8.0e-07 1.5e-06 3.4e-06
10 NAcc isoform ratio XM_006244513.5 0.04 0.03 4.7e-04 0 0.02 0.02 0.01 1.1e-01 2.6e-04 1.3e-03 8.2e-03
11 Liver isoform ratio XM_006244513.5 0.04 0.03 1.5e-04 0.01 0.03 0.02 0.02 1.6e-02 3.6e-04 2.5e-03 1.6e-03
12 NAcc isoform ratio XM_006244515.5 0.02 0.01 7.9e-03 0.01 0 0 0 1.4e-02 6.2e-02 5.6e-02 1.4e-01
13 PL isoform ratio XM_006244515.5 0.07 0.05 5.6e-04 0.02 0.02 0.02 0.03 1.5e-03 2.8e-03 1.3e-03 8.4e-04
14 Adipose gene expression Aars2 0.24 0.09 0.0e+00 0.17 0.16 0.16 0.17 5.2e-19 2.3e-17 1.5e-17 3.1e-18
15 Adipose isoform ratio XM_006244515.5 0.03 0.02 1.9e-03 0.03 0.02 0.01 0.03 2.8e-04 2.8e-03 1.6e-02 4.0e-04
16 PL alternative polyA XM_006244515.5 0.06 0.03 1.5e-05 0.06 0.03 0.05 0.05 8.2e-07 3.9e-04 6.8e-06 5.2e-06
17 PL alternative polyA NM_001106891.1 0.07 0.04 4.5e-06 0.06 0.03 0.05 0.06 2.2e-07 1.2e-04 4.2e-06 1.2e-06
18 Liver gene expression Aars2 0.24 0.08 0.0e+00 0.22 0.24 0.24 0.24 1.4e-24 3.7e-26 3.8e-26 3.0e-26
19 Brain isoform ratio XM_006244515.5 0.07 0.04 8.5e-06 0.04 0.05 0.04 0.05 4.4e-05 1.2e-05 1.2e-04 1.1e-05
20 NAcc alternative polyA NM_001106891.1 0.06 0.03 4.8e-07 0.02 0.04 0.03 0.04 1.1e-03 6.0e-07 5.0e-06 9.7e-07
21 NAcc gene expression Aars2 0.13 0.05 2.2e-16 0.1 0.11 0.12 0.12 4.4e-15 6.9e-17 3.8e-17 8.3e-18
22 Brain isoform ratio NM_001106891.1 0.05 0.03 1.2e-03 0.02 0.02 0.01 0.02 6.9e-03 6.5e-03 3.6e-02 5.5e-03
23 NAcc alternative polyA XM_006244515.5 0.06 0.03 4.9e-08 0.02 0.05 0.04 0.04 4.0e-04 8.1e-08 1.3e-06 3.1e-07
24 Brain gene expression Aars2 0.11 0.05 6.3e-10 0.12 0.11 0.11 0.11 3.4e-11 3.3e-10 1.0e-10 9.7e-11
25 Adipose isoform ratio XM_006244513.5 0.03 0.02 5.0e-03 0 0 0.01 -0 2.1e-01 2.0e-01 2.6e-02 4.5e-01
26 PL mRNA stability Aars2 0.03 0.02 5.0e-03 0.02 0.01 0.02 0.02 1.4e-03 4.1e-02 6.0e-03 5.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.50.93.00.30.1-0.1-0.70.70.2-0.1-1.2-0.6-0.1-0.01.20.10.90.91.2-1.21.6-1.1-1.3-1.41.71.3-1.7-0.50.0
Area under the delay curve3.44.09.9-3.12.6-2.51.3-1.3-2.72.43.03.1-2.5-2.31.82.71.81.91.2-1.20.61.8-0.31.9-1.70.31.2-1.50.0
BMI with tail2.07.117.60.0-1.92.0-0.40.4-0.0-2.01.20.22.32.1-3.8-0.9-3.8-3.7-3.83.8-4.22.53.72.8-3.2-3.83.33.00.0
BMI without tail3.09.019.41.4-3.13.2-1.81.81.1-3.20.1-0.93.43.3-3.8-2.1-4.2-4.2-4.34.3-4.41.93.92.1-2.5-3.92.73.00.0
Body weight1.98.516.82.5-3.83.8-2.92.92.0-4.0-1.9-2.43.94.0-3.5-2.7-4.1-4.0-3.43.4-3.10.82.80.3-0.6-2.80.82.50.0
Weight adjusted by age0.10.10.5-0.20.1-0.10.0-0.0-0.70.20.00.2-0.1-0.2-0.00.6-0.5-0.70.2-0.20.20.20.20.3-0.2-0.2-0.10.40.0
Bone surface1.83.39.5-0.51.5-1.60.3-0.3-0.51.1-0.80.1-1.4-1.32.81.12.52.42.7-2.73.1-1.1-2.5-1.62.12.5-2.5-1.60.0
Bone volume1.32.37.3-0.21.1-1.10.1-0.1-0.30.8-1.0-0.2-1.0-0.92.30.81.81.82.3-2.32.7-1.2-2.1-1.52.02.2-2.3-0.90.0
Breakpoint value in progressive ratio session0.81.02.2-0.71.2-1.21.2-1.2-0.61.50.50.6-1.5-1.51.10.91.01.01.5-1.51.1-0.2-0.9-0.20.30.9-0.3-0.30.0
Number of licking bursts0.60.92.01.2-1.21.2-1.21.21.4-1.1-1.3-1.21.31.1-0.7-1.4-0.8-0.9-0.60.6-0.3-0.70.0-0.90.7-0.0-0.60.80.0
Context. condit. distance diff. score1.41.74.51.1-1.41.40.0-0.00.9-1.5-0.6-1.31.21.5-1.9-1.1-2.0-2.1-1.61.6-1.50.81.70.6-0.6-1.60.90.90.0
Locomotion velocity, session 10.91.03.0-1.71.3-1.31.0-1.0-1.41.01.41.2-1.3-1.00.61.50.80.90.5-0.50.40.90.00.9-0.7-0.00.6-1.10.0
Locomotion distance, session 10.20.31.8-0.40.4-0.41.3-1.3-0.00.20.6-0.2-0.6-0.3-0.10.00.30.3-0.30.3-0.30.40.40.5-0.6-0.30.5-1.10.0
Locomotion velocity, session 21.61.95.5-0.3-1.01.0-0.00.00.3-1.20.8-0.50.31.2-2.2-0.5-1.6-1.6-2.02.0-2.01.22.31.5-1.8-2.31.90.20.0
Locomotion distance, session 20.40.61.6-0.80.4-0.41.2-1.2-0.40.21.20.3-0.6-0.2-0.50.3-0.10.0-0.70.7-0.70.80.91.2-1.3-0.91.1-0.60.0
Locomotion velocity, session 30.70.82.3-1.30.6-0.61.3-1.3-0.90.71.50.7-1.3-0.6-0.00.9-0.0-0.1-0.50.5-0.60.60.81.2-1.4-0.81.30.10.0
Locomotion distance, session 30.50.52.0-0.70.8-0.81.4-1.4-0.90.61.00.6-0.8-0.70.60.80.60.60.1-0.10.00.60.10.7-0.6-0.10.4-0.60.0
Stereotopy head waving bouts, day 30.20.21.00.5-0.50.5-0.70.70.7-0.8-0.8-0.51.00.70.0-0.6-0.3-0.2-0.20.2-0.10.1-0.0-0.30.40.1-0.40.20.0
Stereotopy head waving duration, day 30.20.30.9-0.1-0.40.4-0.20.20.2-0.40.10.00.60.4-0.6-0.2-0.9-0.8-0.70.7-0.70.60.70.5-0.5-0.70.60.70.0
Locomotion velocity, session 70.60.71.6-0.51.0-1.11.1-1.10.00.90.20.2-1.1-0.91.20.31.31.01.2-1.21.0-0.3-0.8-0.20.30.8-0.4-0.80.0
Locomotion distance, session 70.70.83.3-1.11.2-1.21.8-1.8-1.01.01.20.9-1.0-1.10.41.00.50.50.3-0.3-0.00.40.20.9-0.9-0.10.8-0.40.0
Stereotopy head waving bouts, day 70.80.92.10.7-1.11.1-0.80.81.1-1.4-0.8-0.91.41.3-0.6-1.1-1.3-1.4-0.70.7-0.70.71.00.10.0-0.90.10.50.0
Stereotopy head waving duration, day 70.40.51.30.7-0.80.8-0.70.71.1-1.0-1.0-0.91.01.0-0.3-1.0-0.7-0.7-0.20.2-0.00.10.3-0.40.5-0.2-0.50.00.0
Locomotion velocity, session 80.30.41.5-0.10.6-0.61.2-1.20.30.4-0.2-0.5-0.9-0.50.8-0.10.70.60.8-0.81.0-0.6-0.6-0.50.60.6-0.5-0.30.0
Locomotion distance, session 80.60.82.20.0-0.20.31.5-1.50.3-0.50.6-0.7-0.20.4-1.1-0.4-0.7-0.8-1.31.3-1.20.91.41.1-1.1-1.31.2-0.30.0
Degree of sensitization distance0.20.20.6-0.60.3-0.30.2-0.2-0.50.20.60.4-0.2-0.2-0.40.4-0.4-0.3-0.10.1-0.40.30.50.6-0.7-0.50.80.20.0
Degree of sensitization stereotypy0.20.30.90.0-0.40.4-0.20.20.3-0.7-0.1-0.30.60.7-0.3-0.4-0.8-0.9-0.30.3-0.40.90.80.5-0.3-0.80.3-0.10.0
Conditioned locomotion1.72.04.1-1.91.8-1.81.5-1.5-2.01.71.61.6-1.8-1.71.52.01.71.81.1-1.10.80.7-0.60.8-0.50.60.4-1.20.0
Cocaine response after cond. corrected0.30.32.10.2-0.10.1-0.40.4-0.10.2-0.7-0.3-0.1-0.2-0.10.3-0.1-0.10.4-0.40.6-1.4-0.6-1.00.80.6-0.61.40.0
Cocaine response after cond. not corrected0.40.41.7-0.20.2-0.3-0.10.1-0.50.5-0.50.0-0.4-0.50.20.80.20.20.9-0.90.9-1.3-0.8-0.90.80.8-0.61.30.0
Cocaine response before conditioning0.91.01.9-1.31.4-1.41.1-1.1-1.21.20.81.0-1.2-1.31.11.31.11.11.2-1.21.00.4-0.60.3-0.00.6-0.1-1.10.0
Saline control response0.40.52.7-1.00.9-0.90.4-0.4-0.91.00.60.5-1.6-1.00.71.00.40.41.0-1.00.7-0.3-0.50.00.00.50.0-0.00.0
Bone: connectivity density0.61.02.7-0.00.4-0.5-0.70.7-0.10.2-0.8-0.0-0.2-0.31.40.51.41.41.4-1.41.6-0.7-1.4-1.11.51.4-1.6-0.90.0
Bone: cortical apparent density0.20.21.90.3-0.0-0.00.1-0.10.3-0.4-0.7-0.30.60.30.4-0.10.40.40.5-0.50.60.4-0.4-0.40.70.4-0.7-1.40.0
Bone: cortical area0.30.52.40.40.2-0.21.2-1.20.4-0.2-0.6-1.1-0.30.00.7-0.20.80.70.6-0.60.8-0.6-0.4-0.50.60.5-0.7-1.50.0
Bone: cortical porosity0.40.51.60.3-0.70.7-0.90.90.3-0.50.40.00.50.6-0.7-0.6-0.4-0.5-1.31.3-1.10.20.80.4-0.7-0.80.70.60.0
Bone: cortical porosity0.30.41.60.2-0.40.4-0.30.30.1-0.20.60.20.30.3-0.7-0.4-0.3-0.5-1.31.3-1.10.20.80.6-0.9-0.80.80.60.0
Bone: cortical thickness0.20.31.80.4-0.40.40.9-0.90.4-0.8-0.1-0.90.40.7-0.4-0.50.0-0.0-0.50.5-0.50.30.70.4-0.4-0.70.3-1.30.0
Bone: cortical thickness0.30.40.90.6-0.20.10.1-0.10.7-0.5-0.8-0.80.40.40.7-0.60.80.70.2-0.20.6-0.6-0.7-0.80.80.7-0.9-0.90.0
Bone: cortical tissue density0.20.21.80.20.0-0.10.0-0.00.2-0.3-0.7-0.30.50.20.5-0.00.40.40.6-0.60.70.4-0.4-0.40.80.5-0.7-1.30.0
Condit. Reinf. active minus inactive responses0.91.02.70.20.7-0.71.6-1.60.40.8-0.7-0.7-0.8-0.91.2-0.10.90.81.3-1.31.4-1.1-1.2-1.11.11.3-1.2-0.70.0
Condit. Reinf. active-inactive response ratio0.50.51.40.80.1-0.10.8-0.80.60.3-1.1-0.70.0-0.30.5-0.40.20.00.8-0.80.9-0.9-0.9-1.11.21.0-1.20.00.0
Condit. Reinf. active responses0.50.61.60.30.3-0.31.1-1.10.60.4-0.7-1.0-0.9-0.50.7-0.30.30.20.9-0.91.0-1.3-0.8-1.00.90.8-0.9-0.10.0
Condit. Reinf. inactive responses0.20.30.90.0-0.60.6-0.70.70.4-0.5-0.0-0.5-0.20.5-0.6-0.4-0.9-0.9-0.40.4-0.4-0.40.70.1-0.3-0.70.40.90.0
Incentive salience index mean0.50.62.70.10.5-0.51.6-1.60.40.6-0.4-0.8-1.0-0.70.6-0.20.60.50.7-0.70.8-0.9-0.7-0.70.70.7-0.7-0.60.0
Condit. Reinf. lever presses0.10.20.5-0.2-0.30.40.5-0.50.2-0.10.3-0.5-0.40.2-0.6-0.3-0.5-0.6-0.70.7-0.6-0.20.70.2-0.4-0.70.50.20.0
Condit. Reinf. active minus inactive responses0.40.53.3-0.30.9-0.91.8-1.8-0.50.80.20.1-0.4-0.80.80.60.70.80.4-0.40.5-0.4-0.6-0.20.10.6-0.3-0.20.0
Condit. Reinf. active-inactive response ratio0.20.21.70.40.2-0.21.3-1.30.00.1-0.5-0.50.3-0.20.40.10.00.10.3-0.30.3-0.4-0.3-0.40.30.4-0.40.60.0
Condit. Reinf. active responses0.91.34.3-1.21.6-1.62.1-2.1-1.31.41.21.0-1.3-1.41.11.31.21.40.7-0.70.60.1-0.60.4-0.40.60.1-0.80.0
Condit. Reinf. inactive responses0.91.23.0-1.71.5-1.41.0-1.0-1.51.21.51.5-1.4-1.20.71.41.31.30.6-0.60.40.7-0.30.8-0.70.30.4-1.30.0
Condit. Reinf. lever presses0.20.21.5-0.50.5-0.51.2-1.2-0.50.40.60.3-0.3-0.40.10.40.30.4-0.30.3-0.10.40.10.5-0.5-0.10.2-0.30.0
Condit. Reinf. lever reinforcers received0.91.24.8-1.11.5-1.52.2-2.2-1.21.31.10.8-1.3-1.31.01.21.21.30.6-0.60.60.1-0.60.4-0.40.60.0-0.80.0
Conditioned reinforcement - actives0.20.31.7-0.50.4-0.41.3-1.3-0.90.40.3-0.1-0.7-0.5-0.30.7-0.3-0.40.1-0.10.1-0.10.50.4-0.5-0.40.6-0.10.0
Conditioned reinforcement - inactives0.40.61.6-0.80.1-0.11.0-1.0-0.9-0.10.60.1-0.10.0-0.80.7-0.3-0.4-0.50.5-0.81.11.01.1-1.2-1.01.3-1.00.0
Conditioned locomotion0.10.20.70.8-0.40.40.0-0.00.4-0.4-0.7-0.80.40.3-0.7-0.5-0.3-0.1-0.20.20.1-0.40.0-0.40.40.0-0.2-0.20.0
Patch foraging indifference point 0 sec0.40.83.1-0.4-0.40.4-0.20.2-1.0-0.70.40.51.10.7-1.20.4-1.2-1.0-1.01.0-1.11.71.31.1-1.1-1.31.10.10.0
Patch foraging indifference point AUC1.82.66.8-2.21.6-1.62.5-2.5-2.61.42.41.7-1.5-1.40.22.20.61.0-0.00.0-0.51.60.91.9-1.9-0.91.7-1.90.0
Delay disc. indifference point, 0s delay3.23.59.9-2.12.6-2.63.1-3.1-1.92.51.72.2-1.4-2.51.82.01.51.71.4-1.41.31.3-0.81.0-0.40.80.0-1.90.0
Delay disc. indifference point, 16s delay1.61.75.3-2.01.7-1.70.0-0.0-1.41.61.82.3-1.7-1.61.31.71.61.61.0-1.00.71.1-0.80.9-0.70.70.3-1.20.0
Delay disc. indifference point, 2s delay2.32.66.6-2.42.1-2.11.4-1.4-2.12.12.42.6-1.8-2.01.22.11.31.60.9-0.90.31.2-0.21.5-1.30.21.1-1.10.0
Delay disc. indifference point, 24s delay0.50.52.2-1.30.2-0.2-0.30.3-0.7-0.01.20.8-0.70.0-0.50.60.00.1-0.20.2-0.41.50.81.1-1.0-0.81.1-0.50.0
Delay disc. indifference point, 4s delay3.43.59.4-2.72.3-2.21.8-1.8-2.52.33.13.0-1.9-2.21.42.31.41.60.3-0.3-0.22.00.22.2-2.1-0.31.6-1.30.0
Delay disc. indifference point, 8s delay3.03.57.2-2.72.5-2.41.3-1.3-2.62.22.22.3-2.6-2.22.32.71.81.91.7-1.71.21.1-0.81.2-1.00.80.5-1.10.0
Indifference point function ln k0.50.93.10.7-1.11.1-1.81.81.1-0.8-0.6-0.11.40.9-1.1-1.1-1.1-1.3-0.80.8-0.50.10.4-0.20.1-0.5-0.11.70.0
Indifference point function log k0.50.93.10.7-1.11.1-1.81.81.1-0.8-0.6-0.11.40.9-1.1-1.1-1.1-1.3-0.80.8-0.50.10.4-0.20.1-0.5-0.11.70.0
Patch foraging total patch changes 0 sec0.50.93.9-0.5-0.30.30.1-0.1-1.0-0.60.60.71.20.6-1.30.5-1.1-1.0-1.11.1-1.22.01.31.3-1.2-1.31.20.10.0
Patch foraging total patch changes 12 sec1.11.55.2-0.80.1-0.11.1-1.1-1.4-0.41.30.60.30.4-0.90.8-0.8-0.6-1.11.1-1.52.31.81.9-1.8-1.81.8-0.80.0
Patch foraging total patch changes 18 sec0.61.04.4-1.61.0-1.01.3-1.3-2.10.60.90.8-0.7-0.70.31.80.30.70.6-0.60.31.10.30.9-0.6-0.30.5-1.50.0
Patch foraging total patch changes 24 sec0.91.55.8-1.10.4-0.41.1-1.1-1.8-0.11.61.00.20.1-0.91.1-0.7-0.5-1.01.0-1.32.41.62.1-1.9-1.61.8-0.70.0
Patch foraging total patch changes 6 sec1.01.54.3-0.6-0.30.40.4-0.4-1.2-0.81.00.50.90.8-1.40.4-1.3-1.3-1.51.5-1.72.12.01.8-1.7-2.01.9-0.20.0
Patch foraging time to switch 0 sec1.32.65.61.3-0.10.0-2.12.11.5-0.0-1.5-0.9-0.8-0.02.2-0.81.61.31.7-1.72.1-2.2-2.4-2.22.32.3-2.20.40.0
Patch foraging water rate 0 sec1.32.77.6-1.60.5-0.52.6-2.6-1.9-0.01.51.00.7-0.1-1.71.2-1.5-1.2-1.21.2-1.42.82.32.4-2.2-2.22.0-0.80.0
Patch foraging water rate 12 sec1.73.59.8-0.3-0.80.82.0-2.00.2-1.00.6-0.31.40.9-2.8-0.7-3.1-2.9-2.42.4-2.32.02.91.9-1.9-2.82.11.70.0
Patch foraging water rate 18 sec1.11.64.80.2-0.80.80.3-0.30.4-0.90.30.21.50.9-2.0-0.8-2.2-2.2-1.71.7-1.51.61.71.2-1.1-1.71.21.30.0
Patch foraging water rate 24 sec1.52.26.80.4-1.11.10.7-0.70.8-1.1-0.0-0.22.21.1-2.6-1.1-2.3-2.1-2.32.3-1.81.51.90.9-0.9-1.90.90.80.0
Patch foraging water rate 6 sec0.50.85.4-0.80.8-0.82.3-2.3-0.30.70.90.5-0.1-0.7-0.80.2-0.4-0.3-0.40.4-0.31.20.71.0-0.7-0.70.7-0.20.0
Seeking ratio, delayed vs. immediate footshock0.10.21.60.6-0.30.3-0.30.30.5-0.3-0.4-0.30.40.40.1-0.7-0.4-0.7-0.10.10.2-0.00.1-0.30.1-0.1-0.31.30.0
Distance traveled before self-admin1.11.42.90.9-1.51.5-0.60.61.2-1.7-0.6-1.11.71.7-1.7-1.4-1.2-1.5-1.51.5-1.50.31.30.2-0.2-1.30.50.40.0
Distance traveled after self-admin0.20.21.5-0.1-0.20.20.3-0.30.00.1-0.3-0.3-0.1-0.1-0.60.1-1.1-1.20.4-0.4-0.1-0.30.5-0.10.0-0.4-0.01.20.0
Extensor digitorum longus weight0.20.72.00.6-0.90.90.3-0.30.4-1.0-0.8-1.01.11.0-0.9-0.6-1.2-1.3-1.11.1-0.8-0.10.8-0.2-0.0-0.70.01.40.0
Bone: elastic displacement0.30.31.50.8-0.70.7-1.21.20.8-0.6-0.6-0.70.20.6-0.1-0.70.1-0.0-0.20.2-0.1-0.8-0.2-0.60.50.2-0.5-0.10.0
Bone: elastic work2.02.66.62.4-2.12.1-1.91.92.5-2.0-2.2-2.61.32.0-0.6-2.3-0.5-0.7-0.80.8-0.2-1.7-0.3-1.71.50.3-1.60.40.0
Bone: endosteal estimation1.02.36.00.20.9-1.00.4-0.4-0.01.1-1.1-0.3-0.9-1.12.10.51.71.52.0-2.02.4-1.6-2.4-1.92.12.4-2.3-0.30.0
Bone: endosteal perimeter0.91.95.10.30.9-0.90.8-0.80.11.0-0.9-0.5-1.2-1.12.00.41.61.52.0-2.02.3-1.4-1.9-1.61.82.0-1.9-0.70.0
Epididymis fat weight3.913.224.72.7-4.44.5-3.53.52.4-4.6-0.9-2.04.64.7-4.3-3.4-4.7-4.5-5.05.0-4.61.84.21.4-1.8-4.22.12.30.0
Delta time in closed arm before/after self-admin0.60.53.40.8-0.90.9-1.81.80.4-0.9-0.3-0.11.00.9-0.5-0.7-0.40.0-0.70.7-0.50.10.2-0.20.1-0.2-0.10.40.0
Delta time in open arm before/after self-admin1.61.63.9-2.01.5-1.51.7-1.7-1.71.72.01.9-1.5-1.60.51.60.50.50.2-0.2-0.00.80.41.4-1.2-0.41.1-0.70.0
Diff in mean of infusions in LGA sessions0.50.51.81.2-0.60.6-0.60.61.4-0.1-1.0-0.80.60.2-0.2-1.2-0.10.10.0-0.00.4-1.1-0.7-1.11.10.7-0.90.60.0
Delay discount exponential model param3.53.910.23.2-2.52.4-1.11.12.7-2.3-3.1-3.12.62.2-1.7-2.7-1.8-1.9-1.11.1-0.5-1.90.2-2.11.9-0.1-1.41.40.0
Extinction: sum of active levers before priming0.50.61.1-0.51.0-1.01.0-1.0-0.71.00.40.5-0.9-1.00.80.71.00.90.9-0.90.9-0.3-0.7-0.20.30.7-0.4-0.20.0
Active lever presses in extinction session 60.10.10.60.1-0.30.30.2-0.2-0.20.0-0.1-0.6-0.40.0-0.40.1-0.6-0.8-0.10.1-0.4-0.10.3-0.0-0.1-0.3-0.00.60.0
Bone: final force0.40.63.11.0-0.60.60.6-0.60.9-1.0-1.3-1.80.70.8-0.1-0.80.20.2-0.10.10.3-0.7-0.3-1.01.00.3-0.8-1.10.0
Bone: final moment0.30.52.30.9-0.50.40.8-0.80.7-0.9-1.1-1.50.60.7-0.1-0.60.20.2-0.20.20.2-0.4-0.1-0.70.80.2-0.6-1.20.0
Food consumed during 24 hour testing period0.00.00.3-0.10.1-0.1-0.00.00.10.20.10.2-0.2-0.2-0.4-0.2-0.2-0.20.0-0.00.00.50.10.2-0.1-0.10.20.30.0
Glucose1.52.45.00.9-1.81.8-0.50.50.7-1.8-0.4-1.21.91.8-2.2-1.1-2.1-2.1-2.22.2-2.20.72.00.8-1.1-1.91.31.40.0
Heart weight0.60.92.51.1-1.31.3-1.61.60.7-1.5-0.7-1.01.01.5-0.8-0.9-0.8-0.8-0.90.9-0.70.10.6-0.10.1-0.6-0.00.30.0
Delay discount hyperbolic model param3.54.010.03.2-2.52.5-1.21.22.7-2.3-3.0-3.02.52.2-1.8-2.7-1.8-2.0-1.21.2-0.5-1.80.2-2.01.8-0.2-1.31.60.0
Intermittent access intake day 1-15 change0.40.82.50.6-0.0-0.0-0.40.40.60.4-1.1-0.5-0.1-0.30.0-0.30.3-0.31.0-1.01.1-1.6-1.3-1.41.41.3-1.51.10.0
Intermittent access intake escalation0.61.24.60.9-0.20.2-0.70.70.90.3-1.6-0.80.0-0.2-0.0-0.50.3-0.21.2-1.21.3-2.1-1.5-1.91.71.5-1.91.40.0
Intermittent access intake escalation 20.91.12.8-0.10.7-0.7-0.20.2-0.10.8-0.6-0.0-0.9-0.81.10.51.40.81.6-1.61.7-1.3-1.6-1.21.31.6-1.4-0.20.0
Intermitt. access day 1 inactive lever presses0.31.33.41.8-1.51.5-1.01.01.6-1.1-1.7-1.71.31.1-0.7-1.6-0.9-0.9-0.90.9-0.4-1.3-0.1-1.31.00.1-0.80.90.0
Intermitt. access day 15 inactive lever presses0.10.31.0-0.00.0-0.00.2-0.2-0.4-0.10.30.61.00.1-0.80.1-0.20.1-0.80.8-0.90.60.40.6-0.6-0.40.7-0.20.0
Intermitt. access escalation Index0.20.20.5-0.20.2-0.20.6-0.6-0.70.30.60.60.2-0.3-0.50.4-0.4-0.5-0.50.5-0.50.70.40.6-0.6-0.40.70.50.0
Intermittent access day 1 total infusions0.20.41.1-0.1-0.60.6-0.50.5-0.8-0.5-0.0-0.20.30.5-1.10.4-1.1-0.7-0.70.7-0.80.30.80.4-0.6-0.80.70.00.0
Intermittent access day 15 total infusions0.40.62.10.7-0.70.7-1.01.00.3-0.4-1.3-0.80.40.4-0.9-0.2-0.7-0.90.3-0.30.3-1.4-0.4-1.10.90.4-0.91.30.0
Intermittent access terminal intake (last 3 days)0.10.20.80.1-0.10.1-0.60.6-0.4-0.0-0.6-0.4-0.2-0.0-0.40.40.0-0.20.5-0.50.4-0.9-0.3-0.60.40.4-0.40.10.0
Intermittent access total infusions0.10.10.4-0.3-0.10.1-0.40.4-0.60.1-0.10.1-0.2-0.1-0.60.5-0.3-0.40.2-0.20.1-0.30.10.0-0.1-0.10.10.30.0
Intermittent access day 1 locomotion0.70.82.10.6-1.21.2-0.70.70.3-1.1-0.4-0.90.71.2-1.4-0.7-1.2-1.0-1.41.4-1.20.21.10.3-0.4-1.10.50.20.0
Intermittent access day 15 total locomotion0.10.10.60.2-0.50.5-0.60.60.2-0.5-0.5-0.7-0.20.5-0.8-0.2-0.1-0.1-0.10.1-0.1-0.30.1-0.30.3-0.1-0.3-0.40.0
Intermittent access total locomotion0.10.10.60.3-0.50.5-0.50.50.3-0.5-0.5-0.70.00.5-0.8-0.3-0.2-0.2-0.20.2-0.2-0.30.1-0.20.2-0.1-0.2-0.10.0
Intermittent access standard deviation0.30.51.7-0.00.3-0.3-0.60.6-0.20.2-0.6-0.3-0.5-0.20.60.40.90.61.3-1.31.2-0.8-0.9-0.91.01.0-1.1-0.80.0
Left kidney weight0.52.25.50.7-1.71.7-0.90.90.4-1.6-0.3-0.71.71.7-2.4-1.0-2.3-2.3-2.12.1-1.90.81.70.7-0.8-1.71.01.70.0
Right kidney weight0.73.27.7-0.2-1.21.3-0.10.1-0.7-1.50.70.11.71.5-2.4-0.3-2.7-2.5-2.62.6-2.52.42.82.0-2.0-2.71.90.80.0
Cocaine induced anxiety0.20.31.00.7-0.50.5-1.01.00.4-0.3-0.8-0.30.70.3-0.4-0.4-0.2-0.40.0-0.00.1-1.0-0.4-0.90.70.4-0.70.70.0
Post-drug Anxiety1.01.12.91.2-0.60.6-1.71.71.0-0.6-1.6-0.71.00.60.4-0.70.40.30.6-0.60.9-1.2-1.3-1.61.61.2-1.60.20.0
Baseline Anxiety0.80.92.90.10.6-0.7-0.10.10.10.2-0.6-0.2-0.6-0.41.70.31.31.41.4-1.41.5-0.4-1.4-0.91.11.4-1.1-1.10.0
Tail length1.14.39.52.7-3.03.0-2.52.52.2-3.1-2.3-2.62.73.0-1.5-2.5-2.2-2.4-1.71.7-1.1-0.31.2-0.90.8-1.2-0.60.70.0
Length with tail2.29.421.64.5-4.03.9-3.93.94.1-4.0-4.6-4.43.63.9-1.2-4.0-2.1-2.1-1.11.1-0.0-2.1-0.2-3.13.10.3-2.80.80.0
Length without tail1.54.911.03.0-2.92.9-2.82.82.9-3.1-3.3-3.32.53.0-1.5-2.8-1.7-1.7-0.90.9-0.2-1.30.1-2.02.0-0.1-1.70.60.0
Times rat made contact with spout0.50.62.70.2-0.70.8-0.70.70.0-0.70.00.00.80.8-1.7-0.2-1.0-1.0-1.01.0-1.00.80.90.6-0.7-0.90.90.70.0
Lifetime Intake0.10.10.6-0.40.3-0.3-0.20.2-0.80.40.00.3-0.4-0.4-0.20.7-0.1-0.00.4-0.40.3-0.2-0.2-0.0-0.10.20.00.30.0
Liver weight, left0.40.62.0-1.10.0-0.00.2-0.2-1.0-0.11.00.4-0.80.1-1.00.8-0.6-0.6-0.30.3-0.81.31.11.2-1.2-1.11.4-0.30.0
Liver weight, right1.01.74.21.5-2.02.0-1.81.81.2-1.7-1.2-2.10.61.7-1.2-1.4-1.1-1.1-1.21.2-0.9-1.20.7-0.80.4-0.7-0.10.40.0
Locomotor activity1.72.66.32.4-2.22.2-1.91.91.8-2.4-2.2-2.52.12.3-0.9-2.0-1.2-1.3-1.21.2-0.7-0.50.3-1.21.2-0.3-1.1-0.10.0
Locomotor testing distance1.62.87.12.3-2.32.3-1.51.52.0-2.7-2.1-2.62.32.6-1.0-2.2-1.5-1.5-1.51.5-0.9-0.20.7-0.90.9-0.7-0.9-0.40.0
Locomotor testing rearing0.61.23.11.3-1.31.30.3-0.31.1-1.5-1.1-1.81.61.4-0.8-1.3-1.6-1.5-1.21.2-0.8-0.10.9-0.40.2-0.9-0.30.40.0
Locomotion in novel chamber1.01.34.5-1.51.1-1.11.2-1.2-1.51.12.11.5-1.7-1.10.01.30.5-0.1-0.00.0-0.41.20.61.6-1.7-0.71.40.60.0
Locomotion in novel chamber post-restriction2.03.38.8-2.52.3-2.31.6-1.6-2.62.51.61.9-3.0-2.51.82.81.40.72.3-2.31.80.3-0.90.6-0.30.90.30.00.0
Fecal boli incidents, locomotor time 10.30.51.8-0.70.9-0.81.3-1.3-1.00.50.70.5-0.5-0.60.70.70.60.60.4-0.40.10.70.10.6-0.6-0.10.5-1.10.0
Change in fecal boli incidents, locomotor task0.40.41.4-0.50.5-0.5-0.50.5-0.71.00.30.8-1.0-0.90.20.9-0.3-0.20.7-0.70.6-0.3-0.5-0.20.10.5-0.21.20.0
Time >=10cm from walls, locomotor time 10.10.20.9-0.40.4-0.40.9-0.9-0.30.50.40.5-0.2-0.5-0.10.3-0.2-0.0-0.00.0-0.10.60.00.3-0.2-0.00.20.30.0
Bouts of movement, locomotor time 10.50.61.8-0.90.3-0.30.5-0.5-1.30.41.00.9-0.3-0.4-0.00.8-0.9-0.7-0.20.2-0.71.30.91.1-1.2-0.91.10.80.0
Total resting periods, locomotor time 10.30.31.0-0.40.1-0.10.6-0.6-0.90.10.40.40.2-0.1-0.10.5-0.9-0.7-0.00.0-0.51.00.70.6-0.6-0.70.60.60.0
Rest time, locomotor task time 11.11.34.1-1.51.5-1.51.5-1.5-2.01.21.41.6-0.5-1.30.51.70.40.70.7-0.70.11.40.21.0-1.0-0.21.0-1.10.0
Distance moved, locomotor task time 10.20.40.90.3-0.90.9-0.20.20.8-0.6-0.3-0.80.10.7-0.5-0.7-0.6-0.7-1.01.0-0.8-0.60.5-0.10.1-0.50.10.50.0
Vertical activity count, locomotor time 10.20.51.70.7-0.91.0-0.90.91.1-0.5-0.5-1.0-0.40.6-0.2-0.9-0.4-0.4-0.60.6-0.3-1.3-0.0-0.70.50.0-0.20.80.0
Time >=10cm from walls, locomotor time 20.10.11.00.6-0.30.3-0.30.31.0-0.1-0.3-0.20.40.2-0.4-0.8-0.10.0-0.10.1-0.2-0.3-0.3-0.40.30.3-0.10.40.0
Bouts of movement, locomotor time 20.40.61.8-0.6-0.30.30.0-0.0-0.1-0.60.60.20.10.5-0.80.0-1.1-1.1-0.90.9-0.81.21.41.3-1.0-1.30.80.20.0
Total resting periods, locomotor time 20.20.41.2-0.5-0.30.3-0.30.3-0.1-0.40.60.30.10.4-0.6-0.0-1.0-1.0-0.80.8-0.61.01.11.0-0.8-1.10.60.40.0
Rest time, locomotor task time 20.50.61.7-1.01.0-1.00.7-0.7-1.11.01.11.3-0.5-0.90.30.90.60.60.4-0.40.31.0-0.00.6-0.70.00.8-0.50.0
Distance moved, locomotor task time 20.10.10.80.1-0.00.00.4-0.40.30.2-0.2-0.4-0.3-0.20.5-0.20.10.10.2-0.20.1-0.9-0.3-0.50.50.3-0.40.00.0
Vertical activity count, locomotor time 20.60.83.00.30.3-0.40.1-0.10.40.7-0.5-0.4-1.0-0.61.10.01.21.20.9-0.91.1-1.7-1.3-1.21.21.3-1.1-0.40.0
Light reinforcement 10.10.20.60.2-0.40.40.3-0.30.1-0.5-0.1-0.50.10.5-0.2-0.3-0.8-0.7-0.40.4-0.30.60.70.2-0.1-0.70.1-0.30.0
Light reinforcement 20.30.51.51.2-0.80.8-0.50.50.9-0.7-0.9-1.00.70.7-0.6-1.0-0.8-0.9-0.40.4-0.2-0.40.1-0.60.7-0.1-0.50.60.0
Bone: marrow area1.12.46.20.30.9-1.00.3-0.30.11.0-1.2-0.4-1.0-1.12.10.51.81.62.0-2.02.4-1.7-2.5-2.02.22.5-2.4-0.50.0
Bone: maximum diameter0.71.43.1-0.61.4-1.41.8-1.8-0.51.30.20.2-1.5-1.31.70.81.31.31.6-1.61.6-0.4-1.0-0.30.61.1-0.7-1.50.0
Bone: maximum force0.61.14.21.6-0.90.9-0.10.11.6-1.1-1.8-2.00.81.00.0-1.40.20.1-0.10.10.5-1.3-0.8-1.61.60.8-1.5-0.40.0
Bone: maximum moment0.50.93.21.5-0.80.80.1-0.11.4-1.0-1.6-1.80.90.9-0.1-1.20.20.1-0.20.20.4-0.9-0.6-1.31.40.7-1.3-0.50.0
Mean time between licks in bursts0.41.02.4-0.50.9-0.9-0.20.2-0.40.9-0.10.6-0.8-0.91.30.81.51.41.4-1.41.3-0.8-1.6-0.81.01.5-0.9-0.00.0
Mean num. licks in bursts0.50.82.4-1.20.9-0.90.8-0.8-1.60.81.41.4-0.9-0.8-0.21.40.20.40.1-0.1-0.21.30.51.3-1.2-0.51.2-0.30.0
Cd content in liver0.50.51.4-0.00.6-0.70.2-0.2-0.01.20.10.4-1.1-1.10.70.20.70.60.9-0.91.0-1.1-1.0-0.70.61.0-0.70.40.0
Co content in liver0.40.52.70.7-0.70.7-1.21.20.7-0.10.10.00.10.3-0.7-0.9-0.3-0.4-0.80.8-0.7-1.00.0-0.2-0.1-0.10.21.60.0
Cu content in liver0.60.81.8-1.31.2-1.21.1-1.1-1.01.31.01.0-1.3-1.30.71.00.60.80.7-0.70.5-0.0-0.40.3-0.30.40.2-0.10.0
Fe content in liver0.50.72.1-0.3-0.10.20.9-0.9-0.5-0.41.00.1-0.10.4-0.80.2-0.1-0.1-1.01.0-1.20.91.21.3-1.4-1.21.4-0.50.0
K content in liver1.91.84.31.7-1.21.1-1.61.62.1-1.2-2.0-1.70.91.10.6-1.80.50.40.1-0.10.9-1.9-1.2-2.01.91.2-1.80.10.0
Mg content in liver0.20.20.80.1-0.60.6-0.60.60.5-0.9-0.2-0.50.50.9-0.3-0.7-0.0-0.0-0.70.7-0.40.30.40.1-0.1-0.40.0-0.70.0
Mn content in liver0.10.10.70.10.3-0.3-0.10.10.20.3-0.00.80.6-0.20.4-0.10.10.00.4-0.40.40.7-0.40.00.20.4-0.30.60.0
Na content in liver0.70.81.80.8-1.21.2-0.50.50.8-1.3-0.7-1.20.91.3-0.8-0.9-1.2-1.1-1.01.0-0.8-0.10.9-0.1-0.1-0.90.50.60.0
Rb content in liver1.31.64.5-0.81.1-1.20.4-0.4-0.61.0-0.00.3-1.4-1.11.70.92.12.11.5-1.51.7-1.0-1.8-0.91.11.8-1.3-1.00.0
Se content in liver1.21.44.6-1.50.9-0.91.1-1.1-1.60.41.81.6-0.4-0.50.11.3-0.2-0.1-0.30.3-0.72.11.32.0-1.8-1.31.8-0.40.0
Sr content in liver0.50.41.71.1-0.60.6-0.10.11.0-0.4-1.0-1.00.60.4-0.1-0.9-0.2-0.3-0.10.10.1-1.3-0.3-1.00.90.3-0.80.40.0
Zn content in liver0.40.51.3-1.20.8-0.81.1-1.1-0.90.50.90.5-0.9-0.60.40.80.50.60.1-0.10.10.70.30.8-0.7-0.30.6-0.90.0
Bone: minimum diameter0.91.63.90.50.6-0.70.8-0.80.20.5-1.0-0.9-0.8-0.61.80.31.81.71.7-1.72.0-1.5-1.7-1.41.61.8-1.8-1.20.0
Time in familiar zone, hab. session 12.01.94.9-0.5-0.70.8-0.60.6-0.4-0.71.20.60.30.8-1.5-0.1-2.0-1.9-1.71.7-1.91.22.21.7-1.9-2.22.11.90.0
Time in novel zone, hab. session 11.41.43.80.20.9-1.00.9-0.90.31.0-0.70.0-0.3-1.11.10.21.61.51.5-1.51.5-0.8-1.9-1.21.51.9-1.6-1.20.0
Total zone transitions, hab. session 10.50.71.70.1-0.50.50.6-0.60.2-0.50.4-0.50.30.5-1.0-0.4-1.0-0.9-1.31.3-1.30.61.20.9-1.1-1.21.10.30.0
Total locomotion distance, hab. session 10.60.81.90.1-0.60.61.1-1.10.3-0.60.2-0.70.50.6-1.3-0.5-1.2-1.2-1.21.2-1.40.61.30.9-1.1-1.31.10.60.0
Locomotion velocity, hab. session 10.40.61.20.2-0.60.61.0-1.00.3-0.7-0.1-1.00.40.6-1.1-0.5-1.1-1.0-1.01.0-1.10.21.00.5-0.7-1.00.80.50.0
Time in familiar zone, hab. session 20.60.63.10.7-1.01.0-1.81.80.6-0.8-0.8-0.60.50.9-0.1-0.5-0.5-0.6-0.10.10.0-1.0-0.0-0.80.60.0-0.41.30.0
Time in novel zone, hab. session 20.70.73.2-0.60.8-0.71.8-1.8-0.50.50.90.70.1-0.6-0.60.3-0.10.0-0.40.4-0.61.60.61.2-1.0-0.60.9-1.10.0
Total zone transitions, hab. session 20.40.51.41.2-0.80.8-0.50.51.1-0.9-1.0-1.11.00.8-0.2-1.0-0.2-0.4-0.40.4-0.1-0.7-0.1-0.70.60.1-0.70.40.0
Total locomotion distance, hab. session 20.30.41.00.6-0.80.8-0.40.40.7-0.8-0.7-0.80.80.7-0.6-0.6-0.9-1.0-0.50.5-0.5-0.20.5-0.20.1-0.5-0.00.90.0
Locomotion velocity, hab. session 20.20.20.50.5-0.60.6-0.70.70.5-0.6-0.7-0.70.60.6-0.2-0.5-0.5-0.6-0.10.1-0.1-0.40.2-0.40.3-0.1-0.30.70.0
Novel to familiar place preference ratio0.10.10.40.4-0.40.4-0.20.20.3-0.4-0.4-0.30.40.4-0.2-0.2-0.3-0.3-0.20.2-0.1-0.10.1-0.20.1-0.1-0.2-0.70.0
Novelty place preference0.20.20.50.6-0.60.6-0.30.30.6-0.7-0.5-0.60.60.7-0.4-0.5-0.5-0.4-0.40.4-0.3-0.10.3-0.20.1-0.3-0.2-0.70.0
Time in novel zone, NPP test0.20.20.40.3-0.50.5-0.20.20.3-0.6-0.2-0.20.70.6-0.5-0.3-0.6-0.5-0.50.5-0.50.30.50.2-0.2-0.50.2-0.60.0
Total zone transitions, NPP test0.40.51.30.4-0.60.70.4-0.40.5-1.0-0.1-0.80.70.9-0.8-0.6-0.6-0.7-1.01.0-1.00.51.10.5-0.6-1.10.7-0.40.0
Total locomotion distance, NPP test0.40.51.10.5-0.70.70.5-0.50.8-0.9-0.4-1.10.80.9-0.9-0.8-0.6-0.7-0.90.9-0.90.30.90.3-0.4-0.90.4-0.50.0
Locomotion velocity, NPP test0.71.04.11.3-1.21.20.1-0.11.5-1.5-1.2-2.01.11.4-0.8-1.4-0.5-0.6-0.80.8-0.6-0.50.6-0.50.4-0.5-0.3-0.60.0
Intraocular pressure0.20.32.70.5-0.00.0-0.00.0-0.20.6-0.30.2-0.0-0.5-0.40.1-0.3-0.40.4-0.40.1-1.2-0.6-0.70.50.6-0.41.60.0
Delta distance traveled before/after self-admin0.50.51.5-0.50.5-0.50.2-0.2-0.81.2-0.20.3-1.1-1.10.31.0-0.4-0.31.2-1.20.9-0.8-0.5-0.40.30.5-0.51.10.0
Delta ambulatory time before/after self-admin0.60.72.3-0.20.5-0.5-0.30.3-0.51.2-0.50.1-1.1-1.10.30.9-0.2-0.21.5-1.51.3-1.1-0.9-0.90.80.9-1.01.00.0
Parametrial fat weight3.07.015.01.8-3.13.1-1.61.61.7-2.9-0.7-1.53.33.0-3.7-2.5-3.9-3.7-3.73.7-3.61.13.01.0-1.3-3.11.62.70.0
Pavlov. Cond. lever latency0.20.31.00.60.1-0.1-0.30.30.30.3-0.60.20.4-0.20.1-0.10.40.30.6-0.60.7-0.5-1.0-0.80.91.0-1.00.30.0
Pavlov. Cond. magazine entry latency0.50.72.8-1.21.1-1.11.7-1.7-1.01.00.90.7-1.1-1.00.50.90.20.10.4-0.40.30.20.10.6-0.6-0.10.60.10.0
Pavlov. Cond. change in total contacts0.30.41.1-0.80.4-0.41.0-1.0-0.40.40.80.4-0.4-0.40.00.3-0.5-0.4-0.30.3-0.50.60.70.8-0.9-0.71.00.20.0
Pavlov. Cond. index score0.30.41.4-0.90.4-0.41.2-1.2-0.50.20.70.1-0.6-0.30.00.4-0.4-0.4-0.20.2-0.30.40.80.8-0.9-0.80.90.00.0
Pavlov. Cond. latency score0.30.41.7-1.00.6-0.51.3-1.3-0.60.30.80.2-0.8-0.40.30.6-0.0-0.0-0.10.1-0.20.40.60.8-0.8-0.60.8-0.40.0
Pavlov. Cond. lever contacts0.40.51.5-0.5-0.30.30.3-0.3-0.1-0.30.7-0.1-0.20.3-0.5-0.1-0.7-0.8-0.90.9-1.10.51.20.9-1.0-1.21.20.20.0
Pavlov. Cond. magazine entry number0.40.42.00.8-0.60.6-1.41.40.6-0.6-0.8-0.40.60.60.1-0.50.50.60.0-0.00.2-0.4-0.6-0.70.80.6-0.8-0.60.0
Pavlov. Cond. intertrial magazine entries0.00.00.30.2-0.20.2-0.30.30.5-0.10.20.0-0.10.10.0-0.40.20.2-0.30.3-0.30.10.00.2-0.1-0.00.20.10.0
Pavlov. Cond. lever-magazine prob. diff.0.30.41.7-0.90.4-0.41.3-1.3-0.60.30.80.2-0.7-0.4-0.10.5-0.5-0.5-0.20.2-0.40.30.80.7-0.9-0.70.90.30.0
Pavlov. Cond. response bias0.30.41.1-0.60.00.00.7-0.7-0.3-0.00.60.1-0.30.0-0.50.2-0.9-1.0-0.60.6-0.70.41.10.8-0.9-1.01.00.60.0
Pavlov. Cond. lever latency0.20.31.2-0.70.5-0.5-0.50.5-0.80.70.71.1-0.6-0.60.60.80.20.20.4-0.40.10.3-0.00.4-0.30.00.40.20.0
Pavlov. Cond. magazine entry latency0.50.62.20.8-0.90.90.5-0.51.1-1.1-0.6-1.50.71.0-1.4-1.2-0.4-0.4-0.90.9-0.8-0.10.70.0-0.2-0.60.2-0.60.0
Pavlov. Cond. change in total contacts0.50.71.81.0-1.01.00.1-0.11.2-1.3-0.8-1.31.11.2-1.3-1.3-0.7-0.6-1.11.1-0.8-0.10.6-0.1-0.1-0.60.10.20.0
Pavlov. Cond. index score0.60.82.30.8-0.91.00.5-0.51.1-1.3-0.6-1.41.01.2-1.5-1.2-0.6-0.6-1.21.2-0.90.20.90.2-0.3-0.80.3-0.40.0
Pavlov. Cond. latency score0.60.92.40.9-1.01.00.5-0.51.1-1.3-0.6-1.41.01.2-1.5-1.3-0.7-0.7-1.31.3-1.00.30.90.3-0.4-0.90.4-0.30.0
Pavlov. Cond. lever contacts0.30.41.70.9-0.70.70.3-0.30.9-0.9-0.8-1.30.70.9-0.8-1.0-0.3-0.3-0.60.6-0.3-0.30.2-0.30.3-0.2-0.3-0.30.0
Pavlov. Cond. magazine entry number0.40.52.1-0.80.6-0.6-0.70.7-1.11.00.61.4-0.5-0.90.91.1-0.0-0.00.6-0.60.40.2-0.30.1-0.00.30.00.90.0
Pavlov. Cond. intertrial magazine entries0.10.10.7-0.1-0.0-0.0-0.80.8-0.30.1-0.20.50.3-0.00.50.4-0.4-0.40.4-0.40.30.2-0.1-0.10.20.1-0.30.50.0
Pavlov. Cond. lever-magazine prob. diff.0.71.02.80.9-1.11.10.2-0.21.2-1.4-0.6-1.51.11.3-1.7-1.3-0.8-0.8-1.31.3-1.10.21.00.2-0.4-1.00.4-0.20.0
Pavlov. Cond. response bias0.30.41.90.7-0.40.40.6-0.61.0-0.8-0.9-1.40.40.7-0.5-0.90.30.2-0.20.20.2-0.5-0.2-0.60.60.3-0.7-0.80.0
Time in closed arm before self-admin0.30.31.80.9-0.60.6-0.20.21.0-0.6-1.0-0.61.30.6-0.3-0.8-0.3-0.5-0.20.2-0.2-0.6-0.1-0.70.70.1-0.50.30.0
Time in closed arm after self-admin1.92.07.71.8-1.71.7-1.31.31.4-1.5-1.1-0.72.81.6-2.1-1.8-1.6-1.5-1.71.7-1.5-0.30.8-0.40.2-0.8-0.01.60.0
Time in open arm before self-admin0.30.30.70.2-0.70.7-0.70.70.0-0.7-0.1-0.7-0.20.7-0.3-0.0-0.8-0.7-0.60.6-0.70.10.60.3-0.5-0.60.50.70.0
Time in open arm after self-admin0.70.83.2-1.30.8-0.81.0-1.0-1.11.21.40.9-1.8-1.10.71.10.20.50.1-0.1-0.10.40.21.0-1.0-0.30.9-0.00.0
Bone: periosteal estimation0.81.84.20.21.0-1.01.3-1.30.00.9-0.9-0.6-1.0-1.01.90.41.61.51.7-1.72.0-1.4-1.8-1.41.61.9-1.8-1.20.0
Bone: periosteal perimeter0.61.03.21.2-0.30.30.5-0.51.1-0.4-1.6-1.8-0.20.30.9-0.80.60.50.8-0.81.3-1.5-0.9-1.51.61.0-1.6-0.80.0
Bone: post-yield work0.60.92.41.5-1.11.1-1.01.01.6-1.0-1.2-1.21.11.0-0.4-1.5-0.3-0.4-0.70.7-0.1-0.8-0.2-1.00.90.2-0.90.30.0
Progressive ratio test 1 active lever presses0.91.12.11.3-1.41.4-1.31.30.8-1.1-1.3-1.21.21.1-1.4-1.0-1.2-1.0-0.80.8-0.7-1.20.3-0.80.5-0.3-0.31.10.0
Progressive ratio test 1 breakpoint0.81.01.81.3-1.31.3-1.31.30.8-1.0-1.3-1.11.11.0-1.3-1.0-1.1-1.0-0.70.7-0.6-1.30.1-0.90.6-0.1-0.51.20.0
Progressive ratio test 1 inactive lever presses0.50.82.20.7-1.11.1-0.50.50.6-1.2-0.7-0.81.31.1-1.5-0.8-1.1-1.1-1.11.1-1.00.20.80.0-0.1-0.80.30.40.0
Progressive ratio test 2 active lever presses1.21.43.91.2-1.51.5-0.80.80.8-1.1-1.0-1.31.11.1-1.9-1.0-1.9-2.0-1.11.1-1.1-1.10.9-0.50.1-0.80.21.90.0
Progressive ratio test 2 breakpoint1.51.74.51.3-1.71.7-1.01.00.9-1.2-1.1-1.31.21.3-2.1-1.2-2.1-2.1-1.21.2-1.2-1.11.0-0.50.1-1.00.22.00.0
Progressive ratio test 2 inactive lever presses0.20.41.4-0.2-0.30.30.1-0.1-0.5-0.30.1-0.00.40.3-1.20.2-1.0-1.1-0.70.7-0.90.40.90.6-0.7-0.90.90.50.0
Incentive Sensitization - Responses1.31.85.40.7-1.41.4-0.40.40.5-1.1-0.1-0.71.11.2-2.2-0.9-2.1-2.3-1.71.7-1.90.31.70.7-1.0-1.71.21.60.0
Incentive Sensitization - Breakpoint1.21.64.70.5-1.31.3-0.30.30.4-1.1-0.0-0.61.01.1-2.1-0.8-2.0-2.2-1.61.6-1.90.41.70.8-1.1-1.71.31.40.0
Sum of active levers in priming session hrs 5-65.04.710.2-2.82.8-2.82.0-2.0-2.82.92.02.4-3.2-2.92.03.11.81.82.8-2.82.01.0-1.01.0-0.71.00.2-1.00.0
Progressive ratio0.60.92.80.9-0.20.2-0.50.50.9-0.7-1.4-1.10.50.51.2-0.51.10.70.9-0.91.1-0.7-1.3-1.31.71.4-1.6-0.60.0
Food seeking constrained by brief footshock1.11.44.01.2-0.60.5-0.60.61.2-0.5-2.0-1.60.20.40.6-0.70.20.31.0-1.01.3-2.0-1.4-1.92.01.4-1.90.10.0
Seeking ratio, punishment vs. effort0.10.10.3-0.30.2-0.20.6-0.6-0.30.60.10.1-0.5-0.5-0.10.4-0.4-0.30.2-0.20.3-0.40.0-0.0-0.1-0.00.00.20.0
Retroperitoneal fat weight2.08.518.30.5-2.52.6-0.90.91.0-2.80.7-0.33.22.8-3.9-1.8-4.2-4.0-4.14.1-4.33.54.32.8-2.7-4.32.91.80.0
Reaction time number correct1.83.58.8-2.62.2-2.13.0-3.0-2.61.72.42.4-1.2-1.80.52.40.40.50.5-0.5-0.22.80.92.4-2.0-0.81.7-1.90.0
Reaction time mean minus median0.41.02.91.7-0.80.8-0.70.71.5-1.1-1.6-1.41.11.00.2-1.30.70.5-0.10.10.4-1.2-0.8-1.31.30.8-1.1-0.30.0
Reaction time mean minus median AUC0.51.23.21.7-0.50.5-0.40.41.4-0.7-1.7-1.31.10.60.8-1.10.90.90.3-0.30.8-1.4-1.3-1.71.81.3-1.6-0.50.0
Reaction time num false alarms0.50.72.3-1.30.8-0.80.5-0.5-1.50.61.21.2-0.6-0.60.01.20.20.2-0.00.0-0.21.40.41.2-1.2-0.40.9-0.70.0
Reaction time num false alarms AUC0.50.82.2-1.30.7-0.70.4-0.4-1.40.61.41.3-0.6-0.6-0.21.00.20.2-0.30.3-0.51.50.61.4-1.4-0.61.1-0.60.0
Reaction time trials correct on left1.83.58.8-2.62.2-2.13.0-3.0-2.61.72.42.4-1.2-1.80.52.40.40.50.5-0.5-0.22.80.92.4-2.0-0.81.7-1.90.0
Reaction time trials on left1.83.48.5-2.62.1-2.02.9-2.9-2.51.62.42.3-1.1-1.70.42.30.30.50.4-0.4-0.22.80.92.4-2.1-0.91.7-1.80.0
Reaction time mean2.03.28.42.7-2.22.2-2.32.32.9-2.0-2.4-2.31.92.0-0.9-2.6-0.5-0.7-1.01.0-0.3-2.1-0.5-1.91.80.5-1.31.40.0
Reaction time mean AUC1.93.08.32.6-2.12.0-2.02.02.9-1.9-2.4-2.31.91.9-0.8-2.5-0.4-0.6-0.80.8-0.2-2.0-0.6-2.01.90.5-1.41.10.0
Median of all reaction times2.33.28.22.5-2.32.3-2.52.52.9-2.0-2.2-2.21.72.0-1.2-2.5-0.9-1.1-1.11.1-0.5-2.0-0.2-1.71.50.2-1.01.70.0
Reaction time omissions0.71.02.31.3-1.31.3-1.11.11.3-1.5-0.7-1.11.01.5-0.6-1.3-1.1-1.2-1.01.0-0.9-0.10.9-0.00.0-0.90.31.00.0
Reaction time false alarm rate0.10.10.90.1-0.30.3-1.01.0-0.1-0.20.10.10.00.2-0.3-0.10.10.0-0.30.3-0.2-0.1-0.1-0.0-0.10.00.10.30.0
Reaction time premature initiation rate0.10.21.2-0.1-0.20.20.1-0.1-0.3-0.30.30.10.60.4-0.3-0.10.10.2-1.11.1-0.70.40.30.3-0.4-0.30.30.00.0
Reaction time premature initiations0.50.82.8-1.00.6-0.61.4-1.4-1.20.31.21.00.2-0.3-0.10.70.20.4-0.90.9-0.71.70.71.3-1.2-0.70.9-0.80.0
Std. dev. reaction times1.42.67.22.6-1.91.8-1.81.82.7-1.9-2.2-2.21.81.8-0.4-2.4-0.0-0.2-0.70.7-0.1-1.9-0.6-1.81.70.6-1.30.70.0
Reaction time trials completed1.83.48.5-2.62.1-2.02.9-2.9-2.51.62.42.3-1.1-1.70.42.30.30.50.4-0.4-0.22.80.92.4-2.1-0.91.7-1.80.0
Reaction time trials AUC1.63.18.4-2.51.9-1.92.9-2.9-2.31.52.22.1-1.0-1.50.22.10.10.30.3-0.3-0.32.81.02.4-2.0-1.01.7-1.70.0
Run reversals in cocaine runway, females0.70.72.50.70.0-0.10.7-0.70.70.1-1.0-1.1-0.2-0.20.2-0.30.71.00.9-0.91.0-1.0-1.0-1.11.41.1-1.5-1.60.0
Run reversals in cocaine runway, males0.30.31.1-0.10.0-0.00.7-0.7-0.6-0.20.40.50.90.2-0.60.2-0.6-0.6-0.70.7-0.81.00.60.7-0.6-0.60.60.30.0
Latency to leave start box in cocaine runway2.02.36.12.3-1.81.8-0.90.92.5-1.2-2.3-2.21.61.3-1.0-2.4-1.1-1.1-0.90.9-0.2-2.0-0.4-2.01.70.4-1.21.10.0
Latency to leave start box in cocaine runway, F0.60.71.91.3-0.80.80.1-0.11.4-0.6-1.3-1.40.80.6-0.4-1.4-0.5-0.5-0.40.40.1-1.1-0.4-1.31.20.4-0.80.20.0
Latency to leave start box in cocaine runway, M2.52.35.22.1-2.02.0-1.41.42.3-1.4-1.8-1.81.81.5-1.6-2.3-1.5-1.4-1.31.3-0.9-1.60.2-1.31.0-0.2-0.71.70.0
Std. dev. time between licks in bursts0.71.02.1-0.71.1-1.10.8-0.8-0.61.40.50.7-1.4-1.41.20.81.51.41.0-1.01.0-0.7-1.3-0.40.51.2-0.6-0.40.0
Total sessions with >9 infusions0.20.30.7-0.30.7-0.70.8-0.8-0.70.70.20.6-0.1-0.7-0.00.60.50.80.4-0.40.30.0-0.60.0-0.10.60.0-0.30.0
Short access day 1 total inactive lever presses0.10.20.60.1-0.30.4-0.10.10.2-0.10.3-0.10.20.2-0.6-0.3-0.3-0.2-0.80.8-0.70.50.50.5-0.5-0.50.7-0.10.0
Short access day 10 total inactive lever presses0.51.13.9-0.30.1-0.10.8-0.8-0.2-0.31.40.70.60.3-0.4-0.10.20.2-1.41.4-1.62.01.31.8-1.7-1.31.8-1.10.0
Short access day 1 total infusions0.30.41.2-0.50.4-0.30.9-0.9-0.80.50.90.7-0.1-0.5-0.60.5-0.20.0-0.60.6-0.70.50.50.8-1.0-0.51.10.20.0
Short access day 10 total infusions0.20.20.5-0.30.4-0.4-0.30.3-0.70.60.00.3-0.6-0.50.30.70.40.60.7-0.70.5-0.6-0.6-0.30.20.6-0.2-0.20.0
Short access total infusions0.40.51.5-0.70.9-0.90.6-0.6-1.21.10.60.9-0.7-1.10.51.10.60.70.7-0.70.40.1-0.60.2-0.20.60.1-0.20.0
Short access day 1 locomotion0.20.21.1-0.00.5-0.50.7-0.7-0.50.60.30.2-0.4-0.60.00.30.81.00.2-0.20.2-0.3-0.6-0.0-0.10.60.1-0.60.0
Short access day 10 total locomotion0.00.00.20.0-0.10.1-0.30.3-0.1-0.1-0.1-0.2-0.30.10.00.00.30.30.0-0.0-0.1-0.4-0.1-0.10.00.1-0.1-0.40.0
Short access total locomotion0.20.21.2-0.00.4-0.40.5-0.5-0.30.40.10.0-0.3-0.40.30.20.91.10.3-0.30.2-0.2-0.5-0.10.10.5-0.2-1.00.0
One hour access (0.3 mA shock)0.30.41.2-0.80.3-0.30.7-0.7-1.10.60.50.4-1.0-0.6-0.90.9-0.6-0.60.1-0.1-0.10.10.40.6-0.8-0.40.80.90.0
Compulsive drug intake0.80.92.5-1.01.1-1.11.5-1.5-0.51.11.61.6-0.7-1.10.20.60.50.8-0.20.2-0.21.60.21.3-1.1-0.31.0-0.20.0
One hour access (shock baseline)0.30.51.80.3-0.70.7-0.80.8-0.2-0.5-1.0-0.90.10.5-1.10.1-1.2-1.40.2-0.20.1-1.10.3-0.70.4-0.2-0.31.10.0
Social response proportion0.20.20.7-0.50.2-0.2-0.50.5-0.20.2-0.10.1-0.8-0.20.50.30.40.40.8-0.80.5-0.5-0.4-0.20.20.4-0.1-0.60.0
Social responses0.20.21.00.0-0.20.2-0.40.4-0.3-0.1-0.2-0.6-0.90.10.60.20.40.50.3-0.30.2-1.0-0.6-0.60.40.5-0.4-0.80.0
Social time1.72.46.5-2.21.5-1.42.0-2.0-2.51.42.61.7-1.9-1.40.31.90.10.2-0.30.3-0.71.51.02.0-2.2-1.02.0-0.30.0
Soleus weight0.10.31.60.6-0.70.70.6-0.60.4-0.5-0.6-1.30.10.5-0.3-0.6-0.4-0.5-0.60.6-0.4-0.80.3-0.50.4-0.3-0.20.20.0
Bone: stiffness0.00.10.30.1-0.20.10.5-0.50.2-0.3-0.4-0.50.40.3-0.3-0.20.00.1-0.20.20.10.0-0.0-0.20.20.0-0.1-0.40.0
Tibialis anterior weight0.30.92.3-0.0-0.50.51.1-1.1-0.3-0.70.3-0.30.80.6-1.0-0.1-1.2-1.1-1.41.4-1.41.01.50.9-1.0-1.51.00.30.0
Time to tail flick, vehicle, before self-admin0.30.33.6-0.00.1-0.10.4-0.4-0.0-0.5-0.3-0.8-0.00.40.50.10.90.60.4-0.40.30.0-0.1-0.30.40.2-0.3-1.90.0
Time to tail flick, vehicle, after self-admin0.71.02.80.40.1-0.1-0.70.70.40.1-0.8-0.7-0.5-0.11.2-0.11.41.31.2-1.21.2-1.7-1.3-1.31.31.3-1.3-1.40.0
Time to tail flick, test, before self-admin6.16.313.7-2.93.5-3.43.2-3.2-3.13.72.93.1-3.3-3.72.13.32.02.02.4-2.41.30.3-1.11.5-1.61.11.3-0.30.0
Time to tail flick, test, after self-admin0.30.31.7-0.40.6-0.61.3-1.3-0.30.50.60.0-0.5-0.60.20.30.50.4-0.10.1-0.0-0.20.10.3-0.4-0.10.3-0.70.0
Delta time to tail flick, vehicle, before/after SA0.30.30.8-0.30.5-0.50.1-0.1-0.40.80.30.4-0.9-0.80.60.50.60.80.7-0.70.5-0.6-0.5-0.1-0.00.5-0.1-0.00.0
Delta time to tail flick, test, before/after SA3.63.77.52.1-2.72.7-2.12.12.3-2.7-1.7-2.42.32.7-2.0-2.5-1.8-1.8-2.42.4-1.6-0.31.3-0.60.6-1.3-0.40.20.0
Tibia length0.41.03.2-1.20.7-0.71.8-1.8-1.20.71.30.7-0.7-0.7-0.70.9-0.7-0.6-0.60.6-0.71.01.21.4-1.4-1.11.6-0.40.0
Ambulatory time before self-admin1.42.25.90.3-1.31.3-0.10.10.6-1.60.3-0.41.81.6-2.3-1.0-1.6-1.8-2.22.2-2.41.22.11.2-1.3-2.11.50.60.0
Ambulatory time after self-admin0.50.63.10.2-0.70.70.2-0.20.3-0.6-0.4-0.60.90.6-1.3-0.3-1.5-1.8-0.50.5-1.00.21.10.2-0.3-1.00.31.00.0
Bone: tissue strength0.40.41.00.0-0.50.5-0.30.3-0.2-0.50.40.00.40.6-0.9-0.1-0.5-0.5-1.01.0-1.00.70.90.7-0.8-0.90.70.20.0
Total heroin consumption0.30.41.50.7-0.50.5-0.40.40.6-0.3-1.0-1.2-0.40.2-0.0-0.5-0.20.10.6-0.60.7-0.9-0.4-0.91.00.4-1.0-0.20.0
Bone: trabecular number0.40.72.4-0.20.3-0.4-0.30.3-0.2-0.1-0.9-0.6-0.2-0.01.20.61.01.01.3-1.31.6-0.5-1.0-1.01.31.0-1.4-0.90.0
Bone: trabecular spacing0.91.24.4-0.70.00.00.3-0.3-0.90.11.61.1-0.00.0-1.20.5-0.5-0.5-1.11.1-1.71.71.51.8-1.9-1.52.10.10.0
Bone: trabecular thickness2.32.89.10.11.1-1.10.2-0.20.10.9-1.3-0.5-1.0-1.02.50.51.81.92.5-2.53.0-1.5-2.5-1.92.32.5-2.6-1.00.0
Bone: trabecular tissue density3.55.213.9-3.02.5-2.53.7-3.7-3.12.43.33.0-1.6-2.40.22.70.30.40.1-0.1-0.53.11.13.0-2.7-1.12.4-1.20.0
Water consumed over 24 hours0.91.23.8-0.6-0.50.50.1-0.1-0.5-0.80.70.20.50.8-1.80.2-1.5-1.4-1.21.2-1.31.91.81.5-1.4-1.81.60.10.0
Number of responses in last shaping day0.30.32.10.2-0.30.30.4-0.4-0.10.1-0.1-0.10.3-0.0-1.1-0.0-1.2-1.3-0.40.4-0.5-0.30.50.1-0.3-0.50.41.40.0