Hub : Traits

Right kidney weight

Tags: Physiology · Weight

Project: dissection

958 significantly associated models · 161 unique genes

Significant Loci

# chr p0 p1 # assoc genes # joint models best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 169577644 171448580 6 1 1.6e-07 1.5e-07 1.0e+00 100 RGD1311703
2 1 255364313 257116355 2 1 1.1e-07 4.5e-08 4.5e-02 87 Afap1l2
3 1 257860954 260518987 12 5 3.2e-14 7.8e-14 0.0e+00 -3282 Rab11fip2 Cacul1 Nanos1 Zfp950 NA
4 3 105151820 106550924 1 1 2.8e-08 1.1e-05 1.0e+00 100 Ivd
5 3 106655041 108052408 1 1 4.6e-08 9.5e-06 5.7e-03 61 Ganc
6 5 109125119 110519277 1 1 2.6e-07 4.1e-06 3.9e-01 97 Mysm1
7 7 16845355 16970279 1 1 1.1e-43 NaN NA NA NA
8 7 110098486 119313462 94 8 4.3e-13 8.0e-13 NaN NaN Mei1 Ttll1 Trmu Slc25a17 Pnpla3 Rrp7a Serhl2 Cyp2d3
9 7 119468026 121146934 9 1 9.8e-08 1.5e-07 1.0e+00 100 NA
10 9 106993481 108434469 3 2 1.2e-08 7.8e-10 8.4e-12 -23 Arhgap28 AABR07068728.1
11 12 27006 6860177 27 5 2.1e-09 1.2e-08 1.0e+00 100 Rxfp2 Stxbp2 Snapc2 Pet100 Zfp958
12 16 19065621 19932386 1 1 4.7e-09 1.3e-03 6.9e-01 98 NA
13 19 36759451 38410018 3 1 3.6e-08 1.1e-08 6.6e-02 90 Pmfbp1

p0: physical position of the start of the locus. p1: physical position of the end of the locus. # joint models: number of models selected by step-wise conditional analysis.

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
BMI with tail 19.3 31 13 44.8 0.95 6.9e-34 Mapk11 Plxnb2 Sbf1 Ivd Rab11fip2 Ncaph2 Prlhr Cacul1 Dennd10 Prdx3 Grk5 Atxn10 Afap1l2 Nucb2 Pik3c2a Sox6 Plekha7 Nanos1 Ppp6r2 Lmf2 Zfp950 Ces2c Sfxn4 Tafa5 RGD1311703 Selenoo NA NA NA NA Rps13
BMI without tail 22.8 19 13 44.8 0.99 8.6e-40 Rab11fip2 Prlhr Cacul1 Dennd10 Prdx3 Grk5 Nucb2 Pik3c2a Sox6 Plekha7 Nanos1 Zfp950 Ces2c Sfxn4 RGD1311703 NA NA NA Rps13
Body weight 17.7 52 41 141.4 0.96 1.2e-79 Fry Rxfp2 Hsph1 Wdr95 Alox5ap Mcoln1 Camsap3 Xab2 Stxbp2 Trappc5 Evi5l Snapc2 Elavl1 N4bp2l2 Brca2 Ivd Rab11fip2 Prlhr Cacul1 Dennd10 Prdx3 Grk5 Arhgap28 Afap1l2 Fhip2a Nucb2 Pik3c2a Sox6 Plekha7 Nanos1 Arhgef18 Lrrc8e AABR07035218.1 Insr Zfp950 Ces2c Sfxn4 Katnal1 Tafa5 Pet100 RGD1311703 N4bp2l1 B3glct NA NA Zfp958 NA NA NA NA Rps13 NA
Epididymis fat weight 42.3 15 13 44.8 0.98 1.7e-27 Rab11fip2 Prlhr Cacul1 Dennd10 Prdx3 Grk5 Afap1l2 Fhip2a Nanos1 Zfp950 Ces2c Sfxn4 NA NA NA
Glucose 10.8 1 0 0.0 0.00 1.0e+00 Sfxn4
Heart weight 12.1 2 0 0.0 0.00 1.0e+00 Nanos1 Sfxn4
Left kidney weight 13.3 146 126 434.5 1.00 0.0e+00 Ep300 Fry Rxfp2 Hsph1 Wdr95 Alox5ap Mcoln1 Camsap3 Xab2 Stxbp2 Trappc5 Evi5l Snapc2 Elavl1 N4bp2l2 Brca2 Polr3h Csdc2 Pmm1 RGD1306782 Desi1 Xrcc6 Snu13 Mei1 Ccdc134 Srebf2 Septin3 Wbp2nl Cyp2d2 Ivd Rab11fip2 Tcf20 Cyb5r3 Pacsin2 Prlhr Cacul1 Ttll1 Dennd10 Bik Mcat Tspo Scube1 Mpped1 Prdx3 NA Grk5 Pick1 Samm50 Slc16a8 Pla2g6 Phf21b Csnk1e Nup50 Fam118a Fbln1 Josd1 Pmfbp1 Atxn10 Ist1 Sun2 Wnt7b Ttc38 Gtse1 Nptxr Trmu Gramd4 Cerk Tbc1d22a Arhgap28 Syngr1 Afap1l2 Mgat3 Mief1 Grap2 Mchr1 Slc25a17 Xpnpep3 Nucb2 Pik3c2a Sox6 Celsr1 Ppara Pnpla3 Ttll12 Tmem184b Poldip3 Rrp7a Serhl2 Nfam1 Cenpm Aco2 Phf5a Ganc Plekha7 L3mbtl2 Tnrc6b Nanos1 AABR07068728.1 Enthd1 Arhgef18 Lrrc8e Cyp2d5 Cyp2d3 Insr NA RGD1304694 Rangap1 Cyp2d4 Zfp950 Cdpf1 Arhgap8 Ces2c Sfxn4 NA NA Arfgap3 Sult4a1 Katnal1 Tafa5 Shisa8 Pet100 Tob2 NA Parvg Shisal1 RGD1311703 Parvb Zc3h7b Rbx1 N4bp2l1 Cacna1i B3glct NA NA NA NA Zfp958 NA NA NA NA NA NA Rps13 NA Smdt1
Tail length 10.8 19 18 62.1 1.00 1.2e-65 Rxfp2 Mcoln1 Camsap3 Xab2 Stxbp2 Trappc5 Evi5l Snapc2 Elavl1 N4bp2l2 Brca2 Arhgef18 Lrrc8e Insr Pet100 N4bp2l1 NA Zfp958 NA
Length with tail 16.9 30 24 82.8 0.97 5.5e-54 Fry Rxfp2 Hsph1 Wdr95 Alox5ap Mcoln1 Camsap3 Xab2 Stxbp2 Trappc5 Evi5l Snapc2 Elavl1 N4bp2l2 Brca2 Cacul1 Sun2 Arhgef18 Lrrc8e AABR07035218.1 Insr Sfxn4 Katnal1 Pet100 N4bp2l1 B3glct Zfp958 NA NA NA
Length without tail 14.4 31 24 82.8 0.79 4.5e-20 Fry Rxfp2 Hsph1 Wdr95 Alox5ap Mcoln1 Camsap3 Xab2 Stxbp2 Trappc5 Evi5l Snapc2 Elavl1 N4bp2l2 Brca2 Cacul1 Tmem184b Arhgef18 Lrrc8e AABR07035218.1 Insr Sfxn4 Katnal1 Pet100 N4bp2l1 B3glct NA Zfp958 NA NA NA
Liver weight, left 13.9 3 1 3.4 0.98 1.8e-02 Rab11fip2 Cacul1 NA
Liver weight, right 15.0 9 4 13.8 1.00 1.3e-20 Rxfp2 Rab11fip2 Prlhr Cacul1 Grk5 Nanos1 Zfp950 Sfxn4 NA
Parametrial fat weight 22.9 19 13 44.8 0.86 5.4e-15 Rab11fip2 Prlhr Cacul1 Dennd10 Prdx3 Grk5 Nucb2 Pik3c2a Sox6 Plekha7 Nanos1 Zfp950 Ces2c Sfxn4 RGD1311703 NA NA NA Rps13
Retroperitoneal fat weight 18.5 34 15 51.7 0.87 2.3e-34 Polr3h Csdc2 Pmm1 Snu13 Rab11fip2 Prlhr Cacul1 Dennd10 Prdx3 Grk5 Josd1 Sun2 Nptxr Syngr1 Afap1l2 Fhip2a Mgat3 Mief1 Grap2 Slc25a17 Xpnpep3 Phf5a Nanos1 Enthd1 Rangap1 Zfp950 Ces2c Sfxn4 Zc3h7b Rbx1 NA NA NA NA
Intraocular pressure 29.4 1 1 3.4 0.00 1.0e+00 NA
Extensor digitorum longus weight 6.7 20 9 31.0 0.76 1.5e-13 Fry Rxfp2 Mcoln1 Camsap3 Xab2 Stxbp2 Trappc5 Evi5l Snapc2 Elavl1 N4bp2l2 Brca2 Arhgef18 Lrrc8e Insr Pet100 N4bp2l1 NA Zfp958 NA
Soleus weight 11.3 3 1 3.4 0.00 1.0e+00 Afap1l2 Fhip2a NA
Tibialis anterior weight 9.7 20 15 51.7 0.69 1.4e-10 Fry Rxfp2 Mcoln1 Camsap3 Xab2 Stxbp2 Trappc5 Evi5l Snapc2 Elavl1 N4bp2l2 Brca2 Arhgef18 Lrrc8e Insr Pet100 N4bp2l1 NA Zfp958 NA
Tibia length 6.8 12 0 0.0 0.97 8.0e-19 Mcoln1 Stxbp2 Trappc5 Evi5l Snapc2 N4bp2l2 Brca2 Lrrc8e Insr Pet100 N4bp2l1 NA
Number of licking bursts 155.0 1 1 3.4 0.00 1.0e+00 NA
Food consumed during 24 hour testing period 17.5 1 0 0.0 0.00 1.0e+00 NA
Times rat made contact with spout 75.1 1 1 3.4 0.00 1.0e+00 NA
Mean time between licks in bursts 54.9 1 1 3.4 0.00 1.0e+00 NA
Mean num. licks in bursts 164.2 1 1 3.4 0.00 1.0e+00 NA
Std. dev. time between licks in bursts 177.7 1 1 3.4 0.00 1.0e+00 NA
Indifference point 0 sec 16.3 2 1 3.4 0.00 1.0e+00 NA NA
Indifference point AUC 42.1 1 1 3.4 0.00 1.0e+00 NA
Delay discounting total patch changes 0 sec 16.7 2 1 3.4 0.00 1.0e+00 NA NA
Delay discounting total patch changes 12 sec 102.7 1 1 3.4 0.00 1.0e+00 NA
Delay discounting total patch changes 18 sec 175.3 1 1 3.4 0.00 1.0e+00 NA
Delay discounting total patch changes 24 sec 43.7 1 1 3.4 0.00 1.0e+00 NA
Delay discounting total patch changes 6 sec 69.5 2 1 3.4 0.00 1.0e+00 NA NA
Delay discounting water rate 0 sec 11.8 1 0 0.0 0.00 1.0e+00 NA
Delay discounting water rate 12 sec 44.2 1 1 3.4 0.00 1.0e+00 NA
Delay discounting water rate 24 sec 62.7 1 1 3.4 0.00 1.0e+00 NA
Delay discounting water rate 6 sec 44.2 1 1 3.4 0.00 1.0e+00 NA
Locomotor testing distance 14.0 1 0 0.0 0.00 1.0e+00 NA
Locomotor testing rearing 23.9 1 1 3.4 0.00 1.0e+00 NA
Light reinforcement 1 54.8 1 1 3.4 0.00 1.0e+00 NA
Reaction time num false alarms 56.4 1 1 3.4 0.00 1.0e+00 NA
Reaction time num false alarms AUC 79.5 1 1 3.4 0.00 1.0e+00 NA
Reaction time mean 41.3 1 1 3.4 0.00 1.0e+00 NA
Reaction time mean AUC 58.0 1 1 3.4 0.00 1.0e+00 NA
Median of all reaction times 51.2 1 1 3.4 0.00 1.0e+00 NA
Reaction time false alarm rate 63.4 1 1 3.4 0.00 1.0e+00 NA
Reaction time premature initiation rate 32.1 1 1 3.4 0.00 1.0e+00 NA
Reaction time premature initiations 34.3 1 1 3.4 0.00 1.0e+00 NA
Std. dev. reaction times 27.0 1 1 3.4 0.00 1.0e+00 NA
Reaction time trials AUC 15.6 1 0 0.0 0.00 1.0e+00 NA
Social responses 74.3 1 1 3.4 0.00 1.0e+00 NA
Cocaine response after cond. corrected 78.0 1 1 3.4 0.00 1.0e+00 NA
Cocaine response after cond. not corrected 102.3 1 1 3.4 0.00 1.0e+00 NA
Cocaine response before conditioning 28.6 1 1 3.4 0.00 1.0e+00 NA
Saline control response 50.6 1 1 3.4 0.00 1.0e+00 NA
Condit. Reinf. active minus inactive responses 46.4 1 1 3.4 0.00 1.0e+00 NA
Condit. Reinf. active-inactive response ratio 68.7 1 1 3.4 0.00 1.0e+00 NA
Condit. Reinf. inactive responses 20.6 1 0 0.0 0.00 1.0e+00 NA
Pavlov. Cond. lever latency 36.3 1 1 3.4 0.00 1.0e+00 NA
Pavlov. Cond. magazine entry latency 104.9 1 1 3.4 0.00 1.0e+00 NA
Pavlov. Cond. change in total contacts 130.1 1 1 3.4 0.00 1.0e+00 NA
Pavlov. Cond. index score 62.2 1 1 3.4 0.00 1.0e+00 NA
Pavlov. Cond. latency score 67.1 1 1 3.4 0.00 1.0e+00 NA
Pavlov. Cond. lever contacts 29.4 1 1 3.4 0.00 1.0e+00 NA
Pavlov. Cond. magazine entry number 150.0 1 1 3.4 0.00 1.0e+00 NA
Pavlov. Cond. intertrial magazine entries 63.9 1 1 3.4 0.00 1.0e+00 NA
Pavlov. Cond. lever-magazine prob. diff. 55.1 1 1 3.4 0.00 1.0e+00 NA
Pavlov. Cond. response bias 51.3 1 1 3.4 0.00 1.0e+00 NA
Conditioned reinforcement - actives 18.5 1 0 0.0 0.00 1.0e+00 NA
Intermittent access intake day 1-15 change 61.5 1 1 3.4 0.00 1.0e+00 NA
Intermittent access intake escalation 82.5 1 1 3.4 0.00 1.0e+00 NA
Intermittent access intake escalation 2 42.5 1 1 3.4 0.00 1.0e+00 NA
Intermitt. access day 1 inactive lever presses 30.6 1 1 3.4 0.00 1.0e+00 NA
Intermittent access day 1 total infusions 52.9 1 1 3.4 0.00 1.0e+00 NA
Intermittent access day 1 locomotion 27.1 1 1 3.4 0.00 1.0e+00 NA
Cocaine induced anxiety 16.4 1 0 0.0 0.00 1.0e+00 Ganc
Post-drug Anxiety 20.6 1 0 0.0 0.00 1.0e+00 NA
Progressive ratio test 2 breakpoint 38.7 1 1 3.4 0.00 1.0e+00 NA
Short access day 10 total infusions 24.0 1 1 3.4 0.00 1.0e+00 NA
Short access day 1 locomotion 17.2 1 0 0.0 0.00 1.0e+00 NA
Compulsive drug intake 45.4 1 1 3.4 0.00 1.0e+00 NA
Context. condit. distance diff. score 149.8 1 1 3.4 0.00 1.0e+00 NA
Locomotion velocity, session 1 117.8 1 1 3.4 0.00 1.0e+00 NA
Locomotion distance, session 1 374.7 1 1 3.4 0.00 1.0e+00 NA
Locomotion velocity, session 2 82.2 1 1 3.4 0.00 1.0e+00 NA
Locomotion distance, session 2 776.0 1 1 3.4 0.00 1.0e+00 NA
Locomotion velocity, session 3 116.1 1 1 3.4 0.00 1.0e+00 NA
Locomotion distance, session 3 82.4 1 1 3.4 0.00 1.0e+00 NA
Stereotopy head waving duration, day 3 25.6 1 1 3.4 0.00 1.0e+00 NA
Locomotion velocity, session 7 66.3 1 1 3.4 0.00 1.0e+00 NA
Locomotion distance, session 7 31.8 1 1 3.4 0.00 1.0e+00 NA
Stereotopy head waving bouts, day 7 42.6 1 1 3.4 0.00 1.0e+00 NA
Stereotopy head waving duration, day 7 63.4 1 1 3.4 0.00 1.0e+00 NA
Locomotion distance, session 8 102.8 1 1 3.4 0.00 1.0e+00 NA
Degree of sensitization distance 140.6 1 1 3.4 0.00 1.0e+00 NA
Degree of sensitization stereotypy 37.5 1 1 3.4 0.00 1.0e+00 NA
Condit. Reinf. active-inactive response ratio 65.1 1 1 3.4 0.00 1.0e+00 NA
Condit. Reinf. active responses 20.0 1 0 0.0 0.00 1.0e+00 NA
Condit. Reinf. inactive responses 17.2 1 0 0.0 0.00 1.0e+00 NA
Incentive salience index mean 15.6 1 0 0.0 0.00 1.0e+00 NA
Condit. Reinf. lever presses 24.2 2 1 3.4 0.00 1.0e+00 NA NA
Time in novel zone, hab. session 1 17.4 1 0 0.0 0.00 1.0e+00 NA
Total zone transitions, hab. session 1 415.6 1 1 3.4 0.00 1.0e+00 NA
Total locomotion distance, hab. session 1 171.4 1 1 3.4 0.00 1.0e+00 NA
Locomotion velocity, hab. session 1 218.6 1 1 3.4 0.00 1.0e+00 NA
Time in familiar zone, hab. session 2 48.9 1 1 3.4 0.00 1.0e+00 NA
Time in novel zone, hab. session 2 58.4 1 1 3.4 0.00 1.0e+00 NA
Total zone transitions, hab. session 2 256.1 1 1 3.4 0.00 1.0e+00 NA
Total locomotion distance, hab. session 2 133.1 1 1 3.4 0.00 1.0e+00 NA
Locomotion velocity, hab. session 2 139.4 1 1 3.4 0.00 1.0e+00 NA
Novelty place preference 16.1 1 0 0.0 0.00 1.0e+00 Tcf20
Time in novel zone, NPP test 18.1 1 0 0.0 0.00 1.0e+00 Tcf20
Total zone transitions, NPP test 228.8 1 1 3.4 0.00 1.0e+00 NA
Total locomotion distance, NPP test 163.4 1 1 3.4 0.00 1.0e+00 NA
Locomotion velocity, NPP test 195.9 1 1 3.4 0.00 1.0e+00 NA
Pavlov. Cond. magazine entry latency 56.4 1 1 3.4 0.00 1.0e+00 NA
Pavlov. Cond. change in total contacts 28.1 2 1 3.4 0.00 1.0e+00 NA NA
Pavlov. Cond. index score 51.9 1 1 3.4 0.00 1.0e+00 NA
Pavlov. Cond. latency score 16.6 1 0 0.0 0.00 1.0e+00 NA
Pavlov. Cond. lever contacts 16.1 1 0 0.0 0.00 1.0e+00 NA
Pavlov. Cond. magazine entry number 61.6 1 1 3.4 0.00 1.0e+00 NA
Pavlov. Cond. intertrial magazine entries 17.1 1 0 0.0 0.00 1.0e+00 Ganc
Pavlov. Cond. lever-magazine prob. diff. 88.1 1 1 3.4 0.00 1.0e+00 NA
Pavlov. Cond. response bias 52.4 1 1 3.4 0.00 1.0e+00 NA
Bone: apparent density 12.6 6 1 3.4 0.42 1.5e-01 Fry Rxfp2 AABR07035218.1 Katnal1 NA NA
Bone surface 14.0 5 1 3.4 1.00 8.2e-11 Fry Rxfp2 Elavl1 Lrrc8e NA
Bone volume 17.7 5 1 3.4 1.00 1.2e-08 Rxfp2 Cacul1 Sfxn4 NA NA
Bone: connectivity density 12.7 5 0 0.0 1.00 2.5e-11 Fry Rxfp2 Elavl1 Lrrc8e Zfp958
Bone: cortical area 14.3 11 0 0.0 0.99 2.1e-26 Rab11fip2 Prlhr Cacul1 Dennd10 Grk5 Nanos1 Zfp950 Ces2c Sfxn4 NA NA
Bone: cortical porosity 109.3 1 1 3.4 0.00 1.0e+00 NA
Bone: cortical porosity 91.2 1 1 3.4 0.00 1.0e+00 NA
Bone: cortical thickness 10.7 3 0 0.0 1.00 3.0e-04 Rab11fip2 Cacul1 NA
Bone: cortical thickness 17.9 1 0 0.0 0.00 1.0e+00 NA
Bone: elastic displacement 28.2 1 1 3.4 0.00 1.0e+00 NA
Bone: endosteal estimation 18.4 1 1 3.4 0.00 1.0e+00 NA
Bone: final force 15.4 8 1 3.4 0.99 3.0e-11 Rab11fip2 Cacul1 Grk5 Nanos1 Zfp950 Sfxn4 NA NA
Bone: final moment 14.0 8 1 3.4 1.00 2.9e-15 Rab11fip2 Cacul1 Grk5 Nanos1 Zfp950 Sfxn4 NA NA
Bone: marrow area 15.3 1 1 3.4 0.00 1.0e+00 NA
Bone: maximum diameter 9.2 1 0 0.0 0.00 1.0e+00 Cacul1
Bone: maximum force 16.5 6 1 3.4 0.99 1.6e-08 Rab11fip2 Cacul1 Grk5 Sfxn4 NA NA
Bone: maximum moment 13.1 7 1 3.4 1.00 6.6e-14 Rab11fip2 Cacul1 Grk5 Zfp950 Sfxn4 NA NA
Bone: minimum diameter 57.3 1 1 3.4 0.00 1.0e+00 NA
Bone: periosteal estimation 9.7 11 0 0.0 0.97 6.5e-14 Rab11fip2 Prlhr Cacul1 Dennd10 Grk5 Nanos1 Zfp950 Ces2c Sfxn4 NA NA
Bone: periosteal perimeter 11.7 9 0 0.0 0.99 1.8e-16 Rab11fip2 Cacul1 Dennd10 Grk5 Nanos1 Zfp950 Ces2c Sfxn4 NA
Bone: post-yield work 82.8 1 1 3.4 0.00 1.0e+00 NA
Bone: stiffness 90.4 1 1 3.4 0.00 1.0e+00 NA
Bone: tissue strength 81.0 1 1 3.4 0.00 1.0e+00 NA
Bone: trabecular number 20.4 3 1 3.4 -0.44 3.8e-01 Rxfp2 Arhgap28 NA
Bone: trabecular thickness 14.7 6 0 0.0 0.94 5.9e-05 Rab11fip2 Cacul1 Grk5 Nanos1 Sfxn4 NA
Bone: trabecular tissue density 43.1 1 1 3.4 0.00 1.0e+00 NA
Delta time in open arm before/after self-admin 40.2 1 1 3.4 0.00 1.0e+00 NA
Time in closed arm before self-admin 50.0 1 1 3.4 0.00 1.0e+00 NA
Time in closed arm after self-admin 40.2 1 1 3.4 0.00 1.0e+00 NA
Time in open arm after self-admin 31.3 1 1 3.4 0.00 1.0e+00 NA
Delta time to tail flick, test, before/after SA 20.0 1 0 0.0 0.00 1.0e+00 NA
Time >=10cm from walls, locomotor time 1 19.5 1 0 0.0 0.00 1.0e+00 NA
Time >=10cm from walls, locomotor time 2 27.2 1 1 3.4 0.00 1.0e+00 NA
Weight adjusted by age 25.0 1 1 3.4 0.00 1.0e+00 NA
Run reversals in cocaine runway, males 39.3 1 1 3.4 0.00 1.0e+00 NA
Latency to leave start box in cocaine runway 18.8 1 0 0.0 0.00 1.0e+00 NA
Cd content in liver 140.5 1 1 3.4 0.00 1.0e+00 NA
Co content in liver 83.2 1 1 3.4 0.00 1.0e+00 NA
Fe content in liver 14.8 2 0 0.0 0.00 1.0e+00 Rxfp2 B3glct
K content in liver 62.6 1 1 3.4 0.00 1.0e+00 NA
Mn content in liver 130.2 1 1 3.4 0.00 1.0e+00 NA
Rb content in liver 31.4 1 1 3.4 0.00 1.0e+00 NA
Se content in liver 47.0 1 1 3.4 0.00 1.0e+00 NA
Zn content in liver 46.0 1 1 3.4 0.00 1.0e+00 NA

chisq ratio: Average Chi2 statistic for the selected genes in the secondary trait, divided by the average statistic for all genes in the secondary trait. # genes+: Shared significant genes at Bonferroni correction. # genes++: Shared significant genes at transcriptome-wide significance. % genes++: Number of [++] genes as a percentage of primary trait’s total joint genes. corr: Correlation of effect sizes across the [+] genes.

Associations by panel

tissue modality # hits % hits/tests avg chisq
Adipose alternative polyA 18 0.85 3.0
Adipose alternative TSS 11 0.68 3.2
Adipose gene expression 50 0.60 2.7
Adipose isoform ratio 16 0.57 2.8
Adipose intron excision ratio 17 0.58 2.8
Adipose mRNA stability 24 0.70 2.7
BLA alternative polyA 8 0.67 2.9
BLA alternative TSS 9 1.07 3.0
BLA gene expression 44 0.73 2.8
BLA isoform ratio 14 0.80 3.0
BLA intron excision ratio 28 0.94 3.0
BLA mRNA stability 18 0.89 3.1
Brain alternative polyA 11 0.55 2.8
Brain alternative TSS 17 0.99 2.9
Brain gene expression 54 0.60 2.8
Brain isoform ratio 22 0.70 2.8
Brain intron excision ratio 43 0.80 3.0
Brain mRNA stability 34 0.78 2.8
Eye alternative polyA 0 0.00 2.7
Eye alternative TSS 0 0.00 2.9
Eye gene expression 9 0.80 3.0
Eye isoform ratio 0 0.00 2.7
Eye intron excision ratio 6 0.98 3.2
Eye mRNA stability 2 0.86 3.0
IL alternative polyA 4 0.66 3.3
IL alternative TSS 0 0.00 2.6
IL gene expression 26 0.71 2.9
IL isoform ratio 5 0.63 3.2
IL intron excision ratio 7 0.73 2.9
IL mRNA stability 8 0.72 2.7
LHb alternative polyA 1 0.17 2.6
LHb alternative TSS 0 0.00 2.3
LHb gene expression 27 0.84 3.0
LHb isoform ratio 3 0.40 3.0
LHb intron excision ratio 10 0.97 3.0
LHb mRNA stability 7 0.68 2.9
Liver alternative polyA 8 0.53 3.0
Liver alternative TSS 0 0.00 2.6
Liver gene expression 32 0.45 2.6
Liver isoform ratio 12 0.50 2.9
Liver intron excision ratio 30 0.69 2.8
Liver mRNA stability 14 0.57 2.8
NAcc alternative polyA 10 0.76 3.0
NAcc alternative TSS 6 0.65 3.2
NAcc gene expression 54 0.86 2.9
NAcc isoform ratio 15 0.80 2.8
NAcc intron excision ratio 23 0.75 3.1
NAcc mRNA stability 19 0.84 2.9
OFC alternative polyA 6 1.03 3.3
OFC alternative TSS 0 0.00 2.3
OFC gene expression 26 0.70 3.0
OFC isoform ratio 7 0.86 3.1
OFC intron excision ratio 6 0.60 2.8
OFC mRNA stability 8 0.74 2.9
PL alternative polyA 12 0.84 2.9
PL alternative TSS 12 1.02 3.0
PL gene expression 48 0.65 2.8
PL isoform ratio 15 0.68 2.9
PL intron excision ratio 21 0.59 3.0
PL mRNA stability 21 0.72 2.9

avg chisq: Average Chi2 (squared Z-score) across all models in this panel for this trait.