Hub : Traits : Right kidney weight : ← →

chr7:119,468,026-121,146,934

Trait: Right kidney weight

Best TWAS P=9.783379e-08 · Best GWAS P=1.481452e-07 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Ncaph2	alternative polyA	ENSRNOT00000055808	0.02	0.00	blup	1870	0.01	1.0e-02	-5.0	5.1	3.5e-07	-0.98	0.36	0.53	FALSE
2	Adipose	Lmf2	gene expression	ENSRNOG00000030633	0.69	0.62	enet	180	0.63	9.2e-90	-5.1	-5.2	2.2e-07	0.98	0.31	0.69	FALSE
3	Adipose	Plxnb2	intron excision ratio	chr7:120245549:120248063	0.03	0.01	blup	1569	0.01	2.3e-02	-5.1	-5.2	1.7e-07	0.92	0.36	0.55	FALSE
4	BLA	Plxnb2	gene expression	ENSRNOG00000007133	0.32	0.27	enet	26	0.29	8.2e-16	-4.7	5.2	2.6e-07	-0.66	0.39	0.61	FALSE
5	BLA	Ppp6r2	intron excision ratio	chr7:120315244:120324177	0.05	0.03	blup	1603	0.03	7.3e-03	-5.1	-5.1	2.9e-07	0.97	0.38	0.44	FALSE
6	Brain	Plxnb2	gene expression	ENSRNOG00000007133	0.35	0.38	blup	1569	0.39	3.1e-38	-5.1	5.2	1.9e-07	-0.99	0.31	0.69	FALSE
7	Brain	Sbf1	isoform ratio	ENSRNOT00000072955	0.02	0.02	lasso	6	0.02	4.4e-03	-5.1	5.2	1.8e-07	-0.98	0.34	0.56	FALSE
8	Brain	Sbf1	isoform ratio	ENSRNOT00000119425	0.02	0.01	lasso	6	0.02	4.1e-03	-5.1	-5.2	1.6e-07	0.97	0.34	0.56	FALSE
9	Brain	Ppp6r2	intron excision ratio	chr7:120318886:120324177	0.03	0.02	enet	56	0.02	5.9e-03	-5.1	5.2	1.7e-07	-0.90	0.32	0.58	FALSE
10	IL	Mapk11	gene expression	ENSRNOG00000006984	0.22	0.11	blup	1586	0.18	4.8e-05	-4.9	-5.3	1.5e-07	0.95	0.42	0.54	FALSE
11	LHb	Mapk11	gene expression	ENSRNOG00000006984	0.46	0.27	top1	1	0.27	4.6e-07	-5.1	-5.1	3.0e-07	0.98	0.22	0.58	FALSE
12	LHb	Lmf2	gene expression	ENSRNOG00000030633	0.47	0.32	blup	1866	0.36	2.0e-09	-5.1	-5.2	2.0e-07	0.92	0.37	0.63	FALSE
13	Liver	Sbf1	gene expression	ENSRNOG00000008392	0.06	0.05	top1	1	0.05	5.0e-06	-5.2	5.2	2.0e-07	-0.96	0.16	0.69	FALSE
14	Liver	Ncaph2	gene expression	ENSRNOG00000009598	0.12	0.10	top1	1	0.10	4.5e-11	-5.1	5.1	3.4e-07	-0.96	0.27	0.73	FALSE
15	Liver	NA	gene expression	ENSRNOG00000066185	0.31	0.17	top1	1	0.17	7.3e-19	-5.1	-5.1	3.3e-07	0.98	0.28	0.72	FALSE
16	Liver	NA	mRNA stability	ENSRNOG00000066458	0.20	0.20	blup	1913	0.22	5.3e-24	-5.1	5.3	9.8e-08	-0.95	0.28	0.72	TRUE
17	NAcc	Ncaph2	gene expression	ENSRNOG00000009598	0.04	0.03	top1	1	0.03	5.3e-03	-5.1	-5.1	3.0e-07	0.97	0.07	0.07	FALSE
18	NAcc	Selenoo	intron excision ratio	chr7:120171788:120174402	0.07	0.05	blup	1632	0.06	5.3e-05	-4.5	-5.2	2.1e-07	0.91	0.54	0.43	FALSE
19	NAcc	Mapk11	mRNA stability	ENSRNOG00000006984	0.04	0.03	top1	1	0.03	3.4e-03	-5.2	5.2	2.0e-07	-0.98	0.06	0.07	FALSE
20	OFC	Plxnb2	gene expression	ENSRNOG00000007133	0.93	0.39	top1	1	0.39	3.0e-10	-5.1	5.1	3.3e-07	-0.97	0.27	0.72	FALSE
21	PL	Mapk11	gene expression	ENSRNOG00000006984	0.14	0.12	blup	1587	0.14	9.1e-11	-5.0	-5.2	1.9e-07	0.92	0.37	0.63	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.