Hub : Traits : Right kidney weight : ← : →

chr1:267,847,096-270,504,995

Trait: Right kidney weight

Best TWAS P = 7.37e-20 · Best GWAS P= 1.10e-20 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Dennd10	gene expression	Dennd10	0.04	1	0.04	4.7e-05	-7.25	4.26e-13	0.02	FALSE
Adipose	Grk5	gene expression	Grk5	0.19	1480	0.24	3.9e-26	7.95	1.91e-15	0	FALSE
Adipose	LOC120100068	gene expression	LOC120100068	0.03	1	0.02	4.3e-03	-6.46	1.07e-10	0.03	FALSE
Adipose	Prdx3	gene expression	Prdx3	0.19	1	0.24	1.6e-26	-7.29	3.19e-13	0	FALSE
Adipose	Sfxn4	gene expression	Sfxn4	0.02	1	0.02	2.5e-03	-7.32	2.48e-13	0.03	FALSE
Adipose	Zfp933l1	gene expression	Zfp933l1	0.05	19	0.06	4.1e-07	7.8	5.98e-15	0	TRUE
Adipose	Emx2os	intron excision ratio	chr1_268557371_268612388	0.03	1	0.01	1.7e-02	-6.14	8.16e-10	0.03	FALSE
Adipose	Emx2os	mRNA stability	Emx2os	0.19	16	0.15	2.0e-16	-6.6	4.18e-11	0	FALSE
Adipose	LOC120100068	mRNA stability	LOC120100068	0.31	2143	0.18	1.8e-19	7.59	3.18e-14	0	TRUE
BLA	Ces2c	gene expression	Ces2c	0.25	1	0.17	2.6e-09	7.34	2.18e-13	0.83	FALSE
BLA	Emx2os	gene expression	Emx2os	0.38	1	0.21	3.7e-11	-6.27	3.64e-10	0	FALSE
BLA	Rab11fip2	gene expression	Rab11fip2	0.1	2416	0.04	2.2e-03	-7.65	2.08e-14	0.22	FALSE
BLA	Sfxn4	gene expression	Sfxn4	0.07	1	0.02	3.4e-02	9.11	8.28e-20	0.07	FALSE
BLA	Emx2os	mRNA stability	Emx2os	0.3	26	0.12	9.6e-07	-6.63	3.30e-11	0.02	FALSE
BLA	LOC120100068	mRNA stability	LOC120100068	0.37	1	0.11	3.2e-06	6.08	1.20e-09	0.03	FALSE
BLA	Rab11fip2	mRNA stability	Rab11fip2	0.09	1	0.06	3.9e-04	-6.78	1.19e-11	0.04	FALSE
Brain	Ces2c	gene expression	Ces2c	0.23	1	0.27	2.7e-25	7.24	4.41e-13	0.72	FALSE
Brain	Emx2os	gene expression	Emx2os	0.37	2255	0.3	1.8e-28	-5.55	2.90e-08	0	FALSE
Brain	Nanos1	gene expression	Nanos1	0.11	1686	0.09	1.3e-08	-6.82	9.32e-12	0.59	FALSE
Brain	Rab11fip2	gene expression	Rab11fip2	0.1	1	0.06	3.8e-06	-8.02	1.05e-15	0.02	FALSE
Brain	Sfxn4	gene expression	Sfxn4	0.07	1433	0.08	4.5e-08	5.4	6.62e-08	0.11	FALSE
Brain	Zfp933l1	gene expression	Zfp933l1	0.05	2	0.06	5.6e-06	7.47	8.32e-14	0.04	FALSE
Brain	Cacul1	isoform ratio	NM_001014248.2	0.11	36	0.1	1.6e-09	6.2	5.54e-10	0.86	FALSE
Brain	Cacul1	isoform ratio	NM_001416001.1	0.1	1	0.08	3.5e-08	-8.97	2.93e-19	0.61	FALSE
Brain	Cacul1	intron excision ratio	chr1_269663603_269672274	0.11	1	0.08	4.3e-08	8.97	2.93e-19	0.61	FALSE
Brain	LOC134485267	intron excision ratio	chr1_269851730_269854168	0.02	1	0.03	1.9e-03	7.12	1.11e-12	0.03	FALSE
Brain	Emx2os	mRNA stability	Emx2os	0.26	84	0.17	1.8e-15	-5.59	2.31e-08	0	FALSE
Brain	Grk5	mRNA stability	Grk5	0.03	1480	0.02	2.3e-03	-8.51	1.78e-17	0.12	FALSE
Brain	LOC120100068	mRNA stability	LOC120100068	0.5	9	0.2	1.0e-18	6.83	8.44e-12	0	FALSE
IC	Ces2c	gene expression	Ces2c	0.26	1	0.22	1.9e-09	7.26	3.95e-13	0.73	FALSE
IC	Emx2os	gene expression	Emx2os	0.57	1	0.39	1.1e-17	-5.92	3.25e-09	0	FALSE
IC	Grk5	gene expression	Grk5	0.12	1	0.07	7.4e-04	8.97	2.99e-19	0.08	FALSE
IC	Cacul1	isoform ratio	NM_001014248.2	0.1	5	0.04	8.5e-03	8.56	1.11e-17	0.52	FALSE
IC	Cacul1	isoform ratio	NM_001416001.1	0.1	1	0.06	1.1e-03	-7.12	1.08e-12	0.04	FALSE
IL	Ces2c	gene expression	Ces2c	0.38	1	0.3	5.3e-08	7.34	2.18e-13	0.66	FALSE
IL	Sfxn4	mRNA stability	Sfxn4	0.51	1	0.22	4.5e-06	7.24	4.56e-13	0.05	FALSE
LHb	Ces2c	gene expression	Ces2c	0.26	73	0.21	1.2e-05	7.82	5.28e-15	0.69	FALSE
LHb	Rab11fip2	gene expression	Rab11fip2	0.24	1	0.1	2.3e-03	-8.02	1.05e-15	0.05	FALSE
Liver	Nanos1	gene expression	Nanos1	0.08	1	0.06	5.6e-07	-7.24	4.38e-13	0	FALSE
Liver	Cacul1	isoform ratio	NM_001014248.2	0.03	1822	0.01	7.0e-03	6.11	9.95e-10	0.33	FALSE
Liver	Ces2c	mRNA stability	Ces2c	0.02	1	0.01	7.1e-03	-7.3	2.91e-13	0.04	FALSE
Liver	Grk5	mRNA stability	Grk5	0.03	1480	0.01	3.6e-02	-6.37	1.92e-10	0.21	FALSE
NAcc	Ces2c	gene expression	Ces2c	0.15	105	0.21	1.0e-31	7.72	1.18e-14	0.69	FALSE
NAcc	Emx2os	gene expression	Emx2os	0.38	17	0.27	2.4e-40	-5.52	3.35e-08	0	FALSE
NAcc	LOC134485266	gene expression	LOC134485266	0.2	1	0.12	2.3e-18	5.62	1.96e-08	0	FALSE
NAcc	Prlhr	gene expression	Prlhr	0.16	116	0.15	5.0e-22	8.06	7.48e-16	0.93	FALSE
NAcc	Rab11fip2	gene expression	Rab11fip2	0.02	1	0.02	1.6e-03	-6.87	6.35e-12	0.02	FALSE
NAcc	Sfxn4	gene expression	Sfxn4	0.05	14	0.06	1.5e-09	8.81	1.21e-18	0.19	TRUE
NAcc	Cacul1	isoform ratio	NM_001014248.2	0.16	1	0.05	9.7e-08	9.04	1.62e-19	0.74	FALSE
NAcc	LOC134485267	intron excision ratio	chr1_269851730_269854168	0.07	1717	0.04	5.0e-07	7.18	6.81e-13	0.84	FALSE
NAcc	Emx2os	mRNA stability	Emx2os	0.07	1	0.07	1.6e-10	-6.03	1.61e-09	0	FALSE
NAcc	Grk5	mRNA stability	Grk5	0.04	1	0.05	9.3e-08	-7.38	1.58e-13	0	FALSE
OFC	Grk5	alternative TSS	XM_039088827.2	0.1	1	0.13	7.1e-04	7.11	1.19e-12	0.05	FALSE
OFC	Ces2c	gene expression	Ces2c	0.29	1	0.3	5.7e-08	7.03	2.03e-12	0.17	FALSE
OFC	LOC134485266	gene expression	LOC134485266	0.26	2202	0.11	1.2e-03	5.47	4.40e-08	0.13	FALSE
OFC	Rab11fip2	gene expression	Rab11fip2	0.27	164	0.21	8.5e-06	-8.03	9.41e-16	0.33	FALSE
OFC	Rab11fip2	mRNA stability	Rab11fip2	0.27	21	0.18	6.0e-05	-7.37	1.72e-13	0.41	FALSE
PL	Ces2c	gene expression	Ces2c	0.64	31	0.37	6.6e-43	7.25	4.28e-13	0.74	TRUE
PL	Emx2os	gene expression	Emx2os	0.43	2	0.31	5.9e-35	-6.17	6.75e-10	0	FALSE
PL	Nanos1	gene expression	Nanos1	0.11	1686	0.06	1.9e-07	-5.84	5.10e-09	0.27	FALSE
PL	Sfxn4	gene expression	Sfxn4	0.1	1433	0.1	4.4e-11	7.33	2.24e-13	0.07	FALSE
PL	Zfp933l1	gene expression	Zfp933l1	0.05	74	0.03	2.2e-04	6.56	5.56e-11	0.06	FALSE
PL	Cacul1	isoform ratio	NM_001014248.2	0.02	1822	0.01	1.3e-02	9.12	7.37e-20	0.75	TRUE
PL	Emx2os	mRNA stability	Emx2os	0.22	15	0.12	3.0e-13	-6.2	5.57e-10	0	FALSE
pVTA	Ces2c	gene expression	Ces2c	0.34	1	0.35	2.5e-29	7.11	1.15e-12	0.5	FALSE
pVTA	Emx2os	gene expression	Emx2os	0.25	1	0.12	1.0e-09	-6.32	2.61e-10	0	FALSE
pVTA	Sfxn4	gene expression	Sfxn4	0.06	1433	0.04	3.2e-04	7.68	1.57e-14	0.43	FALSE
pVTA	Grk5	mRNA stability	Grk5	0.06	1480	0.05	6.5e-05	-8.54	1.31e-17	0.24	FALSE