Best TWAS P=1.38e-07 · Best GWAS P=1.48e-07 conditioned to 1.00e+00
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Lmf2 | gene expression | Lmf2 | 0.72 | 178 | 0.63 | 2.1e-91 | 5.18 | 2.19e-07 | 0.69 | FALSE |
| Adipose | Plxnb2 | intron excision ratio | chr7_120245549_120248063 | 0.03 | 36 | 0.01 | 3.8e-02 | 5.17 | 2.29e-07 | 0.5 | FALSE |
| BLA | Plxnb2 | gene expression | Plxnb2 | 0.31 | 1568 | 0.28 | 4.0e-15 | 5.25 | 1.50e-07 | 0.61 | FALSE |
| Brain | Mapk11 | isoform ratio | XM_039079917.1 | 0.04 | 1 | 0.04 | 1.2e-04 | 5.22 | 1.80e-07 | 0.18 | FALSE |
| Brain | Sbf1 | isoform ratio | XM_039078878.1 | 0.03 | 1 | 0.04 | 1.9e-04 | 5.2 | 1.95e-07 | 0.13 | FALSE |
| Eye | Lmf2 | gene expression | Lmf2 | 0.45 | 1875 | 0.1 | 1.3e-02 | -5.24 | 1.62e-07 | 0.29 | FALSE |
| IL | Mapk11 | gene expression | Mapk11 | 0.24 | 1588 | 0.19 | 2.2e-05 | -5.26 | 1.47e-07 | 0.53 | FALSE |
| IL | Rabl2 | intron excision ratio | chr7_120659909_120660492 | 0.26 | 1 | 0.3 | 7.7e-08 | 5.2 | 1.95e-07 | 0.56 | FALSE |
| LHb | Lmf2 | gene expression | Lmf2 | 0.31 | 1875 | 0.17 | 6.3e-05 | -5.25 | 1.55e-07 | 0.62 | FALSE |
| LHb | LOC120093828 | gene expression | LOC120093828 | 0.18 | 1 | 0.16 | 1.6e-04 | -5.2 | 1.95e-07 | 0.09 | FALSE |
| LHb | Mapk11 | gene expression | Mapk11 | 0.51 | 1588 | 0.27 | 3.9e-07 | -5.23 | 1.69e-07 | 0.67 | FALSE |
| Liver | LOC102549998 | alternative polyA | XR_005487574.1 | 0.03 | 1890 | 0.02 | 1.2e-03 | -5.26 | 1.46e-07 | 0.52 | FALSE |
| Liver | Tymp | isoform ratio | XM_008765734.3 | 0.07 | 1 | 0.07 | 3.2e-08 | -5.18 | 2.25e-07 | 0.8 | FALSE |
| Liver | Ppp6r2 | mRNA stability | Ppp6r2 | 0.04 | 1601 | 0.03 | 2.9e-04 | -5.27 | 1.38e-07 | 0.64 | TRUE |
| pVTA | Selenoo | gene expression | Selenoo | 0.46 | 1635 | 0.47 | 1.6e-22 | 5.19 | 2.06e-07 | 0.51 | FALSE |