Best TWAS P=2.589178e-07 · Best GWAS P=4.133388e-06 conditioned to 0.3943228
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | Mysm1 | intron excision ratio | chr5:109814620:109816121 | 0.07 | 0 | blup | 2170 | 0 | 0.096 | 3.6 | -5.2 | 2.6e-07 | -0.79 | 0.27 | 0.34 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.