Hub : Traits : Right kidney weight : →

chr1:169,577,644-171,448,580

Trait: Right kidney weight

Best TWAS P=1.597444e-07 · Best GWAS P=1.549822e-07 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Nucb2	alternative TSS	ENSRNOT00000107803	0.04	0.03	lasso	2	0.03	2.8e-04	-5.1	-5.1	3.4e-07	0.97	0.50	0.44	FALSE
2	Adipose	Pik3c2a	mRNA stability	ENSRNOG00000020479	0.10	0.06	top1	1	0.06	6.4e-07	-5.2	5.2	2.4e-07	-0.99	0.29	0.63	FALSE
3	Adipose	RGD1311703	mRNA stability	ENSRNOG00000053659	0.07	0.04	blup	758	0.04	2.5e-05	-5.1	5.1	2.8e-07	-1.00	0.42	0.58	FALSE
4	BLA	Plekha7	gene expression	ENSRNOG00000024602	0.42	0.15	enet	26	0.17	3.5e-09	-5.0	-5.1	3.6e-07	0.99	0.42	0.58	FALSE
5	BLA	Rps13	isoform ratio	ENSRNOT00000118821	0.05	0.03	enet	24	0.04	4.0e-03	-5.1	-5.2	2.6e-07	0.98	0.35	0.40	FALSE
6	Brain	Plekha7	alternative TSS	ENSRNOT00000110407	0.03	0.02	top1	1	0.02	5.5e-03	-5.1	-5.1	3.2e-07	1.00	0.03	0.04	FALSE
7	Brain	RGD1311703	gene expression	ENSRNOG00000053659	0.08	0.05	blup	758	0.05	1.3e-05	-5.1	5.1	3.2e-07	-1.00	0.43	0.57	FALSE
8	Liver	Nucb2	isoform ratio	ENSRNOT00000027752	0.03	0.02	top1	1	0.02	6.1e-03	-5.2	5.2	2.5e-07	-0.98	0.04	0.04	FALSE
9	Liver	Nucb2	isoform ratio	ENSRNOT00000107803	0.03	0.01	top1	1	0.01	1.5e-02	-5.2	-5.2	2.5e-07	0.98	0.03	0.03	FALSE
10	Liver	Nucb2	intron excision ratio	chr1:170756101:170769341	0.04	0.02	top1	1	0.02	4.7e-03	-5.2	5.2	2.5e-07	-0.98	0.03	0.04	FALSE
11	Liver	Sox6	intron excision ratio	chr1:169943000:170010640	0.20	0.01	top1	1	0.01	2.2e-02	-5.2	5.2	2.4e-07	-1.00	0.02	0.03	FALSE
12	NAcc	RGD1311703	alternative polyA	ENSRNOT00000099493	0.05	0.03	enet	168	0.04	8.4e-04	-5.0	-5.2	2.2e-07	0.90	0.40	0.52	FALSE
13	NAcc	RGD1311703	gene expression	ENSRNOG00000053659	0.10	0.08	enet	13	0.08	9.4e-07	-5.1	5.2	1.6e-07	-0.99	0.43	0.57	TRUE
14	PL	Plekha7	gene expression	ENSRNOG00000024602	0.04	0.03	blup	907	0.03	2.3e-03	-5.1	-5.1	3.5e-07	1.00	0.40	0.48	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.