Hub : Traits : Right kidney weight : →

chr1:77,089,603-79,972,411

Trait: Right kidney weight

Best TWAS P = 3.59e-09 · Best GWAS P= 2.23e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Cdc42ep5	alternative TSS	XM_006228217.4	0.02	1749	0.01	4.6e-02	-5.35	8.79e-08	0.44	FALSE
Adipose	Cdc42ep5	alternative TSS	XM_008758944.4	0.03	1749	0.02	6.2e-03	5.31	1.10e-07	0.53	FALSE
Adipose	Tmem150b	alternative TSS	XM_039111106.2	0.03	1532	0.02	3.9e-03	5.4	6.84e-08	0.53	FALSE
Adipose	Ppp6r1	gene expression	Ppp6r1	0.05	174	0.01	2.4e-02	5.44	5.33e-08	0.39	TRUE
Adipose	Rdh13	gene expression	Rdh13	0.19	12	0.13	9.7e-14	-5.43	5.71e-08	0.64	FALSE
Adipose	Tmem150b	gene expression	Tmem150b	0.06	27	0.04	1.3e-05	5.39	7.02e-08	0.65	FALSE
Adipose	Ube2s	mRNA stability	Ube2s	0.09	1608	0.06	1.9e-07	-5.35	8.64e-08	0.66	FALSE
BLA	Cox6b2	gene expression	Cox6b2	0.12	1554	0.07	1.8e-04	5.41	6.44e-08	0.62	FALSE
BLA	Kmt5c	gene expression	Kmt5c	0.05	1540	0.03	1.2e-02	-5.3	1.14e-07	0.39	FALSE
BLA	LOC134482886	gene expression	LOC134482886	0.3	420	0.17	3.0e-09	-5.42	5.87e-08	0.73	FALSE
BLA	Ppp6r1	gene expression	Ppp6r1	0.06	1	0.04	4.1e-03	-5.47	4.41e-08	0.04	FALSE
BLA	Epn1	intron excision ratio	chr1_77773661_77773795	0.19	1	0.03	9.1e-03	-5.25	1.49e-07	0.04	FALSE
BLA	Epn1	intron excision ratio	chr1_77773664_77773795	0.17	1	0.03	6.3e-03	5.25	1.49e-07	0.04	FALSE
BLA	LOC108349515	mRNA stability	LOC108349515	0.1	14	0.06	3.1e-04	5.25	1.49e-07	0.55	FALSE
BLA	Ube2s	mRNA stability	Ube2s	0.08	1608	0.03	1.4e-02	-5.26	1.48e-07	0.48	FALSE
Brain	Tnnt1	alternative TSS	NM_134388.2	0.02	1	0.02	9.1e-03	-5.41	6.13e-08	0.04	FALSE
Brain	Ttyh1	alternative TSS	XM_063283039.1	0.04	54	0.05	4.1e-05	-5.23	1.66e-07	0.55	FALSE
Brain	Cox6b2	gene expression	Cox6b2	0.09	101	0.07	1.9e-07	5.41	6.19e-08	0.64	FALSE
Brain	Gp6	gene expression	Gp6	0.06	15	0.06	5.1e-06	-5.43	5.58e-08	0.64	FALSE
Brain	Isoc2a	gene expression	Isoc2a	0.05	1885	0.06	5.7e-06	5.2	1.94e-07	0.55	FALSE
Brain	Kmt5c	gene expression	Kmt5c	0.11	16	0.13	3.7e-12	-5.25	1.49e-07	0.64	FALSE
Brain	Lair1	isoform ratio	XM_017589623.3	0.03	1	0.01	1.7e-02	5.41	6.41e-08	0.04	FALSE
Brain	Epn1	intron excision ratio	chr1_77786232_77789209	0.03	1	0.03	5.0e-04	-5.26	1.42e-07	0.11	FALSE
Brain	Kmt5c	intron excision ratio	chr1_78132709_78133249	0.05	43	0.04	8.5e-05	-5.31	1.12e-07	0.63	FALSE
Brain	Hspbp1	mRNA stability	Hspbp1	0.06	1509	0.07	1.6e-07	-5.33	9.82e-08	0.63	FALSE
Brain	LOC108349515	mRNA stability	LOC108349515	0.03	1	0.04	4.3e-05	5.38	7.62e-08	0.05	FALSE
Brain	Tnni3	mRNA stability	Tnni3	0.02	1589	0.01	1.3e-02	5.21	1.90e-07	0.42	FALSE
IC	Epn1	intron excision ratio	chr1_77786232_77787609	0.1	1	0.01	7.2e-02	5.43	5.63e-08	0.05	FALSE
IC	Kmt5c	intron excision ratio	chr1_78132709_78133249	0.14	15	0.04	6.3e-03	-5.53	3.24e-08	0.48	FALSE
IL	Dnaaf3	alternative TSS	NM_001271115.1	0.16	1585	0.13	5.1e-04	-5.42	6.06e-08	0.38	FALSE
IL	Dnaaf3	alternative TSS	XM_039101524.2	0.19	1585	0.13	4.5e-04	5.28	1.27e-07	0.38	FALSE
IL	LOC134482886	gene expression	LOC134482886	0.38	1	0.24	1.5e-06	-5.33	9.56e-08	0.1	FALSE
IL	Rpl28	gene expression	Rpl28	0.16	1	0.1	2.2e-03	-5.48	4.21e-08	0.06	FALSE
IL	Tmem86b	gene expression	Tmem86b	0.2	1	0.12	7.2e-04	-5.46	4.64e-08	0.06	FALSE
IL	Lair1	isoform ratio	XM_063272104.1	0.19	1	0.16	1.3e-04	-5.46	4.65e-08	0.08	FALSE
IL	Syt5	mRNA stability	Syt5	0.28	15	0.22	4.9e-06	-5.44	5.41e-08	0.38	TRUE
LHb	Gp6	alternative TSS	XM_039097279.2	0.12	1	0.1	2.2e-03	5.36	8.28e-08	0.05	FALSE
LHb	Dnaaf3	gene expression	Dnaaf3	0.22	15	0.1	1.9e-03	-5.45	5.08e-08	0.45	FALSE
LHb	Kmt5c	gene expression	Kmt5c	0.17	1540	0.07	9.3e-03	-5.37	7.74e-08	0.43	FALSE
LHb	Lair1	isoform ratio	XM_063272104.1	0.31	1	0.19	3.3e-05	-5.33	9.56e-08	0.07	FALSE
LHb	Ppp6r1	isoform ratio	XM_063266289.1	0.13	1489	0.06	1.7e-02	5.3	1.19e-07	0.36	FALSE
Liver	Cox6b2	gene expression	Cox6b2	0.02	1	0.02	2.8e-03	5.45	5.08e-08	0.04	FALSE
Liver	Hspbp1	gene expression	Hspbp1	0.03	1	0.02	1.2e-03	-5.28	1.26e-07	0.04	FALSE
Liver	Rdh13	gene expression	Rdh13	0.08	1557	0.04	3.9e-05	-5.46	4.83e-08	0.59	FALSE
Liver	Tmem190	gene expression	Tmem190	0.03	1535	0.01	1.2e-02	-5.44	5.26e-08	0.47	FALSE
Liver	Tnni3	gene expression	Tnni3	0.04	1589	0.02	1.0e-03	-5.21	1.85e-07	0.37	FALSE
Liver	Lair1	isoform ratio	XM_063272104.1	0.04	1763	0.01	6.9e-02	-5.45	5.02e-08	0.44	FALSE
Liver	Rdh13	isoform ratio	XM_039081520.2	0.03	1557	0.02	5.9e-03	-5.43	5.57e-08	0.58	FALSE
Liver	Ube2s	mRNA stability	Ube2s	0.06	1	0.07	6.0e-08	-5.25	1.49e-07	0.42	FALSE
NAcc	Eps8l1	gene expression	Eps8l1	0.09	1	0.11	7.1e-16	5.24	1.60e-07	0.39	FALSE
NAcc	Gp6	gene expression	Gp6	0.09	1	0.06	3.9e-10	-5.39	7.12e-08	0.6	FALSE
NAcc	LOC108349515	gene expression	LOC108349515	0.15	162	0.09	1.1e-13	5.75	8.76e-09	0.62	FALSE
NAcc	Tnnt1	gene expression	Tnnt1	0.12	1591	0.12	5.4e-18	-5.22	1.76e-07	0.62	FALSE
NAcc	Zfp579	gene expression	Zfp579	0.04	285	0.02	1.4e-03	5.77	7.84e-09	0.2	FALSE
NAcc	Cdc42ep5	isoform ratio	XM_008758944.4	0.02	1	0.01	1.9e-03	5.58	2.44e-08	0.04	FALSE
NAcc	Kmt5c	intron excision ratio	chr1_78132709_78133249	0.06	1	0.05	4.1e-08	-5.39	7.12e-08	0.6	FALSE
NAcc	Tnnt1	intron excision ratio	chr1_78350613_78350777	0.02	1	0.02	2.9e-04	5.27	1.34e-07	0.04	FALSE
NAcc	LOC108349515	mRNA stability	LOC108349515	0.08	178	0.09	5.6e-13	5.9	3.59e-09	0.44	TRUE
OFC	Ccdc106	gene expression	Ccdc106	0.32	2118	0.09	4.0e-03	5.2	1.95e-07	0.47	FALSE
OFC	LOC134482886	gene expression	LOC134482886	0.32	1785	0.17	7.2e-05	-5.44	5.32e-08	0.61	FALSE
OFC	Rdh13	gene expression	Rdh13	0.19	121	0.1	2.2e-03	-5.51	3.57e-08	0.36	FALSE
OFC	Lair1	isoform ratio	XM_063272104.1	0.18	1	0.09	3.7e-03	-5.33	9.56e-08	0.05	FALSE
PL	Cox6b2	gene expression	Cox6b2	0.12	1554	0.11	1.3e-11	5.33	9.78e-08	0.66	TRUE
PL	Hspbp1	gene expression	Hspbp1	0.04	1	0.04	9.4e-05	-5.45	5.08e-08	0.17	FALSE
PL	LOC108349515	gene expression	LOC108349515	0.07	110	0.05	8.0e-06	5.46	4.73e-08	0.56	FALSE
PL	Hspbp1	mRNA stability	Hspbp1	0.03	1	0.01	1.0e-02	-5.47	4.60e-08	0.06	FALSE
pVTA	Hspbp1	gene expression	Hspbp1	0.08	1509	0.01	3.2e-02	-5.22	1.74e-07	0.35	FALSE
pVTA	Lilrb3	intron excision ratio	chr1_79009034_79010203	0.11	19	0.01	2.6e-02	-5.68	1.32e-08	0.19	FALSE
RMTg	LOC134482886	gene expression	LOC134482886	0.18	1	0.07	5.5e-03	-5.49	3.97e-08	0.06	FALSE