chr3:125,435,700-128,734,028

Trait: Right kidney weight

Best TWAS P = 2.11e-10 · Best GWAS P= 3.40e-08 conditioned to 1.92e-01

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Ehd4 gene expression Ehd4 0.07 1486 0.04 3.7e-05 -5.33 9.74e-08 0.72 FALSE
Adipose Vps18 gene expression Vps18 0.12 1 0.08 8.2e-09 5.26 1.47e-07 0.91 FALSE
BLA Rpap1 gene expression Rpap1 0.1 1 0.08 6.6e-05 -5.32 1.03e-07 0.22 FALSE
BLA Pla2g4b isoform ratio XM_006234775.4 0.05 1 0.03 1.7e-02 5.27 1.34e-07 0.04 FALSE
BLA Itpka mRNA stability Itpka 0.08 1 0.03 1.5e-02 -5.32 1.04e-07 0.07 FALSE
Brain Pla2g4b alternative TSS XM_039104945.1 0.02 1 0.02 5.7e-03 5.4 6.48e-08 0.05 FALSE
Brain Ankrd63 gene expression Ankrd63 0.1 98 0.05 2.5e-05 -5.4 6.67e-08 0.07 FALSE
Brain Jmjd7 gene expression Jmjd7 0.08 1503 0.1 1.3e-09 5.28 1.28e-07 0.73 FALSE
Brain Pla2g4b gene expression Pla2g4b 0.15 1 0.21 4.8e-19 5.52 3.40e-08 0.86 FALSE
Brain Vps18 gene expression Vps18 0.03 1 0.03 1.4e-03 5.29 1.20e-07 0.16 FALSE
Brain Mapkbp1 isoform ratio NM_001108589.1 0.09 1 0.11 1.0e-10 5.3 1.17e-07 0.65 FALSE
Brain Mapkbp1 isoform ratio XM_006234781.5 0.1 1 0.12 1.6e-11 -5.3 1.17e-07 0.65 FALSE
Eye C3h15orf62 isoform ratio NM_001399846.1 0.57 1 0.19 6.6e-04 5.3 1.17e-07 0.08 FALSE
Eye C3h15orf62 isoform ratio NM_001399847.1 0.59 1 0.2 4.9e-04 -5.3 1.17e-07 0.08 FALSE
IC Mga intron excision ratio chr3_127328375_127334111 0.09 1 0.05 3.9e-03 -5.26 1.42e-07 0.05 FALSE
IC Sptbn5 intron excision ratio chr3_127467945_127470706 0.12 9 0.09 1.9e-04 -5.21 1.90e-07 0.69 FALSE
IL Sptbn5 gene expression Sptbn5 0.47 1 0.19 3.3e-05 5.46 4.78e-08 0.19 FALSE
IL Itpka mRNA stability Itpka 0.13 1 0.04 4.7e-02 -5.27 1.36e-07 0.05 FALSE
Liver Rpusd2 gene expression Rpusd2 0.05 138 0 9.4e-02 -5.2 1.95e-07 0.59 FALSE
Liver C3h15orf62 isoform ratio NM_001399846.1 0.18 1 0.12 1.8e-13 5.29 1.20e-07 0.95 FALSE
Liver C3h15orf62 isoform ratio NM_001399847.1 0.2 1 0.13 4.5e-14 -5.29 1.20e-07 0.95 FALSE
NAcc Plcb2 alternative polyA XM_063284733.1 0.27 1827 0.07 1.5e-10 5.28 1.30e-07 0.02 FALSE
NAcc Mga alternative TSS XM_008762120.4 0.01 1 0 5.0e-02 -5.43 5.62e-08 0.04 FALSE
NAcc Pla2g4b gene expression Pla2g4b 0.03 1 0.03 9.7e-06 5.32 1.03e-07 0.46 FALSE
NAcc Zfp106 gene expression Zfp106 0.04 1694 0.02 1.8e-04 5.62 1.92e-08 0.82 FALSE
NAcc Plcb2 isoform ratio NM_053478.2 0.14 1827 0.02 1.2e-03 -5.27 1.36e-07 0.03 TRUE
NAcc Stard9 isoform ratio NM_001427830.1 0.03 19 0.01 2.4e-03 -5.32 1.02e-07 0.84 FALSE
NAcc Ganc intron excision ratio chr3_127812058_127812306 0.55 162 0.17 1.4e-24 6.35 2.11e-10 0 TRUE
NAcc Pla2g4b intron excision ratio chr3_127458196_127460407 0.02 1 0.02 8.6e-04 -5.32 1.03e-07 0.07 FALSE
NAcc Pla2g4b intron excision ratio chr3_127459119_127460407 0.02 1 0.01 2.3e-03 5.32 1.03e-07 0.08 FALSE
NAcc Pla2g4b mRNA stability Pla2g4b 0.03 1 0.02 3.0e-04 5.31 1.07e-07 0.42 FALSE
OFC Sptbn5 gene expression Sptbn5 0.33 1 0.14 3.7e-04 5.25 1.48e-07 0.07 FALSE
PL Mga alternative TSS XM_063284962.1 0.03 194 0.01 3.4e-02 5.96 2.49e-09 0.41 FALSE
PL Jmjd7 gene expression Jmjd7 0.03 1503 0.03 1.1e-04 5.28 1.32e-07 0.71 FALSE
PL Mga gene expression Mga 0.02 23 0.02 1.2e-03 -5.32 1.02e-07 0.63 FALSE
PL Rpap1 gene expression Rpap1 0.15 1 0.22 1.1e-23 -5.31 1.07e-07 0.67 FALSE
PL Sptbn5 gene expression Sptbn5 0.28 1462 0.35 2.3e-39 5.4 6.74e-08 0.69 FALSE
PL Mapkbp1 isoform ratio NM_001108589.1 0.02 1 0.01 2.9e-02 5.32 1.03e-07 0.05 FALSE
PL Sptbn5 isoform ratio XM_039106497.2 0.04 1 0.04 3.1e-05 5.32 1.04e-07 0.46 FALSE
PL Mapkbp1 intron excision ratio chr3_127437355_127437545 0.04 1 0.03 4.3e-04 5.31 1.07e-07 0.34 FALSE
PL Mapkbp1 intron excision ratio chr3_127437355_127437672 0.04 1 0.03 3.1e-04 -5.31 1.07e-07 0.38 FALSE
PL Sptbn5 intron excision ratio chr3_127470972_127471250 0.02 23 0.02 5.2e-03 5.41 6.21e-08 0.65 FALSE
pVTA Zfyve19 isoform ratio XM_039105682.2 0.07 5 0.04 2.0e-04 -5.27 1.33e-07 0.73 FALSE
pVTA Ganc mRNA stability Ganc 0.48 122 0.1 1.6e-08 5.87 4.49e-09 0.11 FALSE
RMTg Mga alternative TSS XM_008762120.4 0.13 14 0.1 1.2e-03 -5.34 9.10e-08 0.62 FALSE
RMTg Mga isoform ratio XM_008762120.4 0.11 120 0.06 1.4e-02 -5.32 1.02e-07 0.51 FALSE