Best TWAS P=4.646231e-08 · Best GWAS P=9.537577e-06 conditioned to 0.005667179
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NAcc | Ganc | intron excision ratio | chr3:107358295:107358543 | 0.23 | 0.05 | enet | 33 | 0.07 | 7.5e-06 | -3.6 | 5.5 | 4.6e-08 | -0.33 | 0.6 | 0.18 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.