chr1:102,553,738-104,830,034

Trait: Right kidney weight

Best TWAS P = 3.81e-08 · Best GWAS P= 6.60e-07 conditioned to 2.05e-01

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Prmt1 alternative TSS XM_006229144.5 0.62 29 0.09 2.4e-10 5.2 1.94e-07 0.58 FALSE
BLA Bcl2l12 alternative TSS XM_017589363.3 0.07 15 0.05 1.4e-03 5.26 1.42e-07 0.43 FALSE
Brain Cpt1c isoform ratio NM_001034925.2 0.06 5 0.05 2.7e-05 5.22 1.77e-07 0.57 FALSE
Brain Ctu1 intron excision ratio chr1_103252043_103254866 0.05 3350 0.02 8.0e-03 5.23 1.73e-07 0.59 FALSE
Brain Scaf1 intron excision ratio chr1_104633240_104634999 0.04 100 0.05 4.0e-05 5.23 1.67e-07 0.55 FALSE
IC Syt3 intron excision ratio chr1_104017429_104017749 0.06 2380 0.03 2.2e-02 5.23 1.70e-07 0.36 FALSE
IC Shank1 mRNA stability Shank1 0.16 14 0.14 2.2e-06 5.33 9.65e-08 0.45 FALSE
IL Josd2 mRNA stability Josd2 0.16 2173 0.04 3.7e-02 5.35 8.62e-08 0.3 FALSE
LHb Fuz alternative polyA XM_006229060.5 0.25 114 0.2 2.1e-05 5.37 7.86e-08 0.52 FALSE
LHb Med25 intron excision ratio chr1_104505814_104510610 0.18 48 0.09 4.6e-03 -5.21 1.85e-07 0.38 FALSE
Liver Bcl2l12 mRNA stability Bcl2l12 0.07 73 0.03 3.5e-04 5.31 1.09e-07 0.6 FALSE
NAcc C1h19orf81 intron excision ratio chr1_103994174_103994823 0.03 19 0.02 5.7e-04 5.34 9.23e-08 0.45 FALSE
NAcc Fcgrt mRNA stability Fcgrt 0.02 14 0.02 2.7e-04 -5.21 1.85e-07 0.46 FALSE
NAcc Lrrc4b mRNA stability Lrrc4b 0.06 2313 0.07 1.3e-10 -5.28 1.30e-07 0.45 FALSE
OFC Fuz alternative polyA NM_001399381.1 0.33 112 0.21 1.1e-05 -5.21 1.86e-07 0.52 FALSE
PL Tsks gene expression Tsks 0.04 15 0.04 9.4e-05 5.29 1.22e-07 0.55 FALSE
PL Fuz isoform ratio NM_001399381.1 0.03 16 0.02 6.0e-03 -5.27 1.38e-07 0.4 FALSE
pVTA Cpt1c alternative TSS NM_001034925.2 0.16 14 0.19 1.8e-15 5.21 1.88e-07 0.57 FALSE
pVTA Cpt1c alternative TSS NM_001034925.2 0.2 46 0.23 2.8e-18 5.28 1.31e-07 0.58 FALSE
pVTA Cpt1c alternative TSS XM_063262004.1 0.22 5 0.13 2.4e-10 -5.24 1.63e-07 0.58 FALSE
pVTA Scaf1 isoform ratio XM_063272028.1 0.06 112 0.05 3.6e-05 -5.5 3.81e-08 0.59 TRUE
pVTA Cpt1c mRNA stability Cpt1c 0.03 7 0.02 4.5e-03 -5.29 1.24e-07 0.43 FALSE
pVTA Lrrc4b mRNA stability Lrrc4b 0.06 37 0.07 1.7e-06 -5.31 1.10e-07 0.45 FALSE