Best TWAS P=2.804008e-08 · Best GWAS P=1.051368e-05 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Ivd | alternative polyA | ENSRNOT00000107497 | 0.19 | 0.1 | enet | 158 | 0.10 | 1.3e-11 | -4.2 | 5.5 | 3.4e-08 | -0.96 | 0.07 | 0.92 | FALSE |
| 2 | Adipose | Ivd | alternative polyA | ENSRNOT00000013829 | 0.19 | 0.1 | enet | 177 | 0.10 | 2.5e-11 | -4.2 | -5.4 | 5.3e-08 | 0.97 | 0.07 | 0.92 | FALSE |
| 3 | Adipose | Ivd | alternative polyA | ENSRNOT00000107497 | 0.20 | 0.1 | enet | 142 | 0.11 | 8.7e-12 | -4.2 | 5.6 | 2.8e-08 | -0.96 | 0.06 | 0.92 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.