Hub : Traits : Right kidney weight : ← →

chr12:27,006-6,860,177

Trait: Right kidney weight

Best TWAS P=2.12388e-09 · Best GWAS P=1.196178e-08 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	N4bp2l2	alternative polyA	ENSRNOT00000111844	0.14	0.12	top1	1	0.12	7.1e-13	-5.3	5.3	1.0e-07	-0.94	0.10	0.90	FALSE
2	Adipose	N4bp2l2	alternative polyA	ENSRNOT00000118063	0.14	0.12	top1	1	0.12	3.9e-13	-5.3	-5.3	1.0e-07	0.94	0.10	0.90	FALSE
3	Adipose	B3glct	alternative polyA	ENSRNOT00000083484	0.06	0.03	enet	19	0.03	2.4e-04	-1.9	5.6	1.8e-08	-0.73	0.90	0.09	FALSE
4	Adipose	B3glct	alternative polyA	ENSRNOT00000116254	0.06	0.03	enet	18	0.03	1.9e-04	-1.9	-5.9	4.7e-09	0.73	0.89	0.10	FALSE
5	Adipose	Pet100	alternative TSS	ENSRNOT00000071928	0.22	0.10	enet	116	0.13	3.4e-14	-5.5	5.1	3.0e-07	-0.98	0.23	0.77	FALSE
6	Adipose	Pet100	alternative TSS	ENSRNOT00000107172	0.22	0.10	enet	122	0.13	2.6e-14	-4.3	-5.1	2.6e-07	0.98	0.24	0.76	FALSE
7	Adipose	Hsph1	gene expression	ENSRNOG00000000902	0.56	0.22	enet	55	0.22	1.8e-24	-5.2	-5.4	6.6e-08	0.40	0.52	0.48	FALSE
8	Adipose	Xab2	gene expression	ENSRNOG00000000988	0.14	0.05	top1	1	0.05	2.2e-06	-5.1	-5.1	3.0e-07	0.88	0.43	0.46	FALSE
9	Adipose	Trappc5	gene expression	ENSRNOG00000001003	0.09	0.03	top1	1	0.03	9.9e-05	-5.5	-5.5	3.5e-08	0.58	0.08	0.40	FALSE
10	Adipose	Evi5l	gene expression	ENSRNOG00000001034	0.09	0.00	top1	1	0.00	4.2e-01	-5.6	5.6	2.4e-08	-0.74	0.06	0.07	FALSE
11	Adipose	Insr	gene expression	ENSRNOG00000029986	0.13	0.02	top1	1	0.02	4.3e-03	-5.2	5.2	1.9e-07	-0.56	0.05	0.03	FALSE
12	Adipose	N4bp2l1	gene expression	ENSRNOG00000059322	0.32	0.23	lasso	16	0.24	1.2e-26	-5.4	-5.4	7.2e-08	0.96	0.04	0.96	FALSE
13	Adipose	Pet100	isoform ratio	ENSRNOT00000071928	0.23	0.11	enet	64	0.13	1.8e-14	-5.5	5.2	2.3e-07	-0.97	0.17	0.83	FALSE
14	Adipose	Pet100	isoform ratio	ENSRNOT00000107172	0.23	0.09	enet	66	0.13	2.6e-14	-5.5	-5.2	1.8e-07	0.98	0.16	0.84	FALSE
15	Adipose	Zfp958	isoform ratio	ENSRNOT00000102786	0.03	0.00	enet	169	0.01	6.9e-03	-5.1	5.3	1.5e-07	-0.83	0.23	0.46	FALSE
16	Adipose	Zfp958	intron excision ratio	chr12:3971128:3971331	0.03	0.00	blup	1113	0.01	2.8e-02	-5.1	5.1	3.4e-07	-0.77	0.17	0.39	TRUE
17	Adipose	Fry	mRNA stability	ENSRNOG00000000894	0.08	0.05	blup	2970	0.05	2.0e-06	-4.2	-5.3	1.2e-07	0.70	0.96	0.04	FALSE
18	Adipose	Snapc2	mRNA stability	ENSRNOG00000001056	0.11	0.00	enet	19	0.01	5.0e-02	-3.1	-5.4	5.4e-08	0.71	0.42	0.13	TRUE
19	Adipose	Elavl1	mRNA stability	ENSRNOG00000001069	0.16	0.06	blup	2406	0.07	9.4e-09	-5.0	5.2	1.8e-07	-0.75	0.28	0.72	FALSE
20	BLA	Pet100	alternative TSS	ENSRNOT00000110166	0.11	0.05	top1	1	0.05	7.7e-04	-5.3	-5.3	1.4e-07	0.41	0.07	0.05	FALSE
21	BLA	Wdr95	gene expression	ENSRNOG00000000904	0.15	0.01	blup	2270	0.03	1.5e-02	-4.9	-5.2	1.7e-07	0.57	0.40	0.36	FALSE
22	BLA	Insr	gene expression	ENSRNOG00000029986	0.59	0.33	blup	1546	0.39	5.5e-22	-5.0	5.4	8.6e-08	-0.86	0.44	0.56	FALSE
23	BLA	Camsap3	isoform ratio	ENSRNOT00000101379	0.13	0.06	top1	1	0.06	4.4e-04	-5.3	5.3	1.4e-07	-0.61	0.08	0.06	FALSE
24	BLA	AABR07035218.1	intron excision ratio	chr12:5974685:5975080	0.36	0.15	blup	2412	0.18	9.1e-10	-5.4	5.2	1.5e-07	-0.31	0.20	0.80	FALSE
25	BLA	Pet100	intron excision ratio	chr12:1680794:1680963	0.36	0.12	lasso	13	0.19	1.7e-10	-5.6	-5.5	3.9e-08	0.94	0.16	0.84	FALSE
26	BLA	Pet100	intron excision ratio	chr12:1680995:1681508	0.35	0.12	lasso	11	0.20	9.8e-11	-5.6	5.4	6.2e-08	-0.91	0.17	0.83	TRUE
27	BLA	NA	intron excision ratio	chr12:3870992:3873703	0.08	0.03	blup	1116	0.04	3.3e-03	-5.1	-5.2	2.0e-07	0.84	0.24	0.64	FALSE
28	BLA	Katnal1	mRNA stability	ENSRNOG00000047618	0.21	0.05	blup	2320	0.07	1.7e-04	-1.9	-5.3	9.5e-08	0.34	0.24	0.74	FALSE
29	Brain	Rxfp2	gene expression	ENSRNOG00000000897	0.13	0.07	blup	3311	0.12	3.5e-11	-5.1	-5.9	3.0e-09	0.73	0.67	0.33	FALSE
30	Brain	Elavl1	gene expression	ENSRNOG00000001069	0.07	0.01	blup	2406	0.02	4.4e-03	-5.1	-5.1	3.2e-07	0.76	0.31	0.60	FALSE
31	Brain	Arhgef18	gene expression	ENSRNOG00000028090	0.12	0.06	enet	11	0.08	1.2e-07	-5.1	-5.6	2.7e-08	0.93	0.22	0.78	FALSE
32	Brain	N4bp2l1	gene expression	ENSRNOG00000059322	0.06	0.05	lasso	2	0.05	3.5e-05	-5.4	-5.4	8.7e-08	0.99	0.06	0.93	FALSE
33	Brain	Rxfp2	intron excision ratio	chr12:4945988:4950591	0.07	0.01	lasso	6	0.02	7.0e-03	-5.1	-6.0	2.1e-09	0.43	0.54	0.32	TRUE
34	Brain	Rxfp2	intron excision ratio	chr12:4945988:4950702	0.05	0.01	lasso	5	0.02	7.8e-03	-4.9	5.9	3.8e-09	-0.43	0.54	0.31	FALSE
35	Brain	Trappc5	intron excision ratio	chr12:1737769:1740114	0.05	0.02	enet	18	0.03	5.1e-04	-4.4	-5.8	8.6e-09	0.81	0.46	0.40	FALSE
36	Brain	NA	intron excision ratio	chr12:3870992:3873703	0.13	0.10	lasso	14	0.10	1.0e-09	-5.1	-5.1	3.1e-07	0.83	0.26	0.74	FALSE
37	Brain	Elavl1	mRNA stability	ENSRNOG00000001069	0.19	0.03	lasso	22	0.07	2.6e-07	-5.0	5.1	3.0e-07	-0.54	0.31	0.69	FALSE
38	Brain	Insr	mRNA stability	ENSRNOG00000029986	0.72	0.55	enet	150	0.60	8.8e-69	-5.5	5.1	3.0e-07	-0.97	0.12	0.88	FALSE
39	Brain	Katnal1	mRNA stability	ENSRNOG00000047618	0.33	0.31	blup	2320	0.32	2.0e-30	-5.4	-5.7	1.1e-08	0.48	0.18	0.81	FALSE
40	Eye	Fry	gene expression	ENSRNOG00000000894	0.41	0.13	blup	2972	0.18	9.6e-04	-4.4	-5.4	5.9e-08	0.68	0.50	0.11	FALSE
41	Eye	Elavl1	intron excision ratio	chr12:2667464:2684652	0.69	0.25	lasso	30	0.31	1.3e-05	-5.5	5.5	3.4e-08	-0.92	0.21	0.64	FALSE
42	IL	Katnal1	gene expression	ENSRNOG00000047618	0.47	0.04	blup	2315	0.13	5.7e-04	-4.5	6.0	2.4e-09	-0.54	0.29	0.42	FALSE
43	IL	Insr	intron excision ratio	chr12:1257822:1307450	0.73	0.50	top1	1	0.50	6.5e-14	-5.5	5.5	4.1e-08	-0.94	0.13	0.87	FALSE
44	IL	Katnal1	mRNA stability	ENSRNOG00000047618	0.13	0.09	top1	1	0.09	4.4e-03	-5.4	-5.4	7.1e-08	0.02	0.12	0.08	FALSE
45	LHb	Rxfp2	gene expression	ENSRNOG00000000897	0.27	0.17	lasso	9	0.22	4.8e-06	-4.3	-5.3	9.1e-08	0.56	0.67	0.25	FALSE
46	Liver	N4bp2l2	alternative polyA	ENSRNOT00000111844	0.10	0.04	blup	681	0.07	2.3e-08	-4.9	5.6	2.8e-08	-0.94	0.20	0.80	FALSE
47	Liver	N4bp2l2	alternative polyA	ENSRNOT00000118063	0.10	0.04	blup	681	0.07	1.5e-08	-4.9	-5.5	2.9e-08	0.94	0.20	0.80	FALSE
48	Liver	Mcoln1	gene expression	ENSRNOG00000000975	0.09	0.04	lasso	39	0.04	1.7e-05	-5.5	5.5	4.3e-08	-1.00	0.12	0.88	FALSE
49	Liver	N4bp2l1	gene expression	ENSRNOG00000059322	0.21	0.13	enet	107	0.16	2.5e-17	-5.3	-5.1	2.9e-07	0.96	0.06	0.94	FALSE
50	Liver	Stxbp2	isoform ratio	ENSRNOT00000107607	0.15	0.09	lasso	10	0.09	5.9e-10	-4.4	-5.3	1.3e-07	0.89	0.37	0.63	FALSE
51	Liver	N4bp2l1	isoform ratio	ENSRNOT00000110394	0.06	0.03	blup	587	0.04	6.9e-05	-4.9	5.3	1.2e-07	-0.86	0.16	0.83	FALSE
52	Liver	AABR07035218.1	intron excision ratio	chr12:5974685:5975080	0.13	0.11	top1	1	0.11	4.1e-12	-5.2	5.2	2.5e-07	0.01	0.44	0.56	FALSE
53	Liver	Insr	intron excision ratio	chr12:1257822:1307450	0.44	0.21	enet	94	0.21	3.2e-23	-5.5	5.2	1.6e-07	-0.98	0.11	0.89	FALSE
54	Liver	Pet100	intron excision ratio	chr12:1680794:1680963	0.21	0.04	blup	1823	0.09	1.9e-10	-4.4	-5.2	1.9e-07	0.87	0.44	0.56	FALSE
55	Liver	Zfp958	intron excision ratio	chr12:3953566:3967085	0.09	0.04	top1	1	0.04	1.5e-05	-5.1	5.1	3.1e-07	-0.81	0.16	0.45	FALSE
56	Liver	Zfp958	intron excision ratio	chr12:3971128:3971331	0.07	0.03	top1	1	0.03	7.0e-04	-5.1	5.1	2.9e-07	-0.72	0.06	0.12	FALSE
57	Liver	NA	intron excision ratio	chr12:3870992:3871195	0.09	0.04	top1	1	0.04	1.0e-05	-5.1	5.1	3.3e-07	-0.80	0.14	0.36	FALSE
58	Liver	NA	intron excision ratio	chr12:3870992:3873703	0.18	0.10	top1	1	0.10	7.7e-11	-5.2	-5.2	2.5e-07	0.81	0.21	0.79	FALSE
59	Liver	NA	intron excision ratio	chr12:3871255:3873703	0.14	0.09	top1	1	0.09	6.4e-10	-5.1	5.1	2.9e-07	-0.84	0.24	0.76	FALSE
60	Liver	Elavl1	mRNA stability	ENSRNOG00000001069	0.16	0.05	lasso	4	0.05	3.3e-06	-5.1	5.2	2.5e-07	-0.82	0.28	0.72	FALSE
61	Liver	N4bp2l2	mRNA stability	ENSRNOG00000001108	0.03	0.02	top1	1	0.02	2.0e-03	-5.4	5.4	8.6e-08	-0.97	0.03	0.13	FALSE
62	NAcc	Pet100	alternative TSS	ENSRNOT00000071928	0.08	0.03	top1	1	0.03	1.4e-03	-5.6	5.6	2.7e-08	-0.92	0.07	0.32	FALSE
63	NAcc	Rxfp2	gene expression	ENSRNOG00000000897	0.08	0.04	blup	3309	0.06	1.4e-05	-4.3	-5.5	4.5e-08	0.76	0.93	0.06	FALSE
64	NAcc	Alox5ap	gene expression	ENSRNOG00000000907	0.06	0.07	top1	1	0.06	1.3e-05	-5.1	-5.1	3.5e-07	0.07	0.25	0.18	FALSE
65	NAcc	Stxbp2	gene expression	ENSRNOG00000000994	0.10	0.07	top1	1	0.07	9.6e-06	-5.6	-5.6	2.7e-08	0.93	0.08	0.59	TRUE
66	NAcc	Arhgef18	gene expression	ENSRNOG00000028090	0.13	0.05	blup	1531	0.08	1.3e-06	-3.6	-5.1	3.4e-07	0.84	0.69	0.31	FALSE
67	NAcc	Lrrc8e	gene expression	ENSRNOG00000028460	0.31	0.06	lasso	12	0.07	1.2e-05	-5.5	-5.5	3.0e-08	0.82	0.05	0.93	FALSE
68	NAcc	Katnal1	gene expression	ENSRNOG00000047618	0.26	0.18	blup	2319	0.20	8.3e-15	-5.2	5.5	3.0e-08	-0.44	0.19	0.81	FALSE
69	NAcc	Trappc5	isoform ratio	ENSRNOT00000001327	0.11	0.04	lasso	38	0.04	2.9e-04	-5.5	-5.6	2.6e-08	0.98	0.15	0.85	FALSE
70	NAcc	Trappc5	isoform ratio	ENSRNOT00000111016	0.09	0.02	lasso	29	0.03	5.1e-03	-5.5	5.5	3.6e-08	-0.98	0.16	0.82	FALSE
71	NAcc	Snapc2	mRNA stability	ENSRNOG00000001056	0.13	0.07	top1	1	0.06	1.3e-05	-5.6	-5.6	2.0e-08	0.76	0.02	0.93	FALSE
72	NAcc	Brca2	mRNA stability	ENSRNOG00000001111	0.14	0.09	lasso	42	0.09	4.2e-07	-5.3	5.4	6.2e-08	-1.00	0.05	0.95	FALSE
73	NAcc	Insr	mRNA stability	ENSRNOG00000029986	0.37	0.23	lasso	29	0.23	1.8e-17	-5.5	5.3	1.1e-07	-0.99	0.12	0.88	FALSE
74	OFC	Stxbp2	gene expression	ENSRNOG00000000994	0.43	0.14	top1	1	0.14	2.8e-04	-5.5	-5.5	3.5e-08	0.81	0.09	0.10	FALSE
75	OFC	NA	gene expression	ENSRNOG00000069263	0.24	0.12	top1	1	0.12	1.0e-03	-5.3	-5.3	1.1e-07	0.07	0.14	0.15	FALSE
76	OFC	Insr	intron excision ratio	chr12:1257822:1307450	0.64	0.28	top1	1	0.28	2.2e-07	-5.5	5.5	4.1e-08	-0.93	0.12	0.69	FALSE
77	OFC	Insr	mRNA stability	ENSRNOG00000029986	0.82	0.37	top1	1	0.37	1.0e-09	-5.5	5.5	5.0e-08	-0.96	0.15	0.80	FALSE
78	PL	NA	gene expression	ENSRNOG00000067247	0.10	0.07	blup	2289	0.07	3.7e-06	-5.4	5.9	3.5e-09	-0.45	0.20	0.80	FALSE
79	PL	Pet100	intron excision ratio	chr12:1679962:1680708	0.08	0.03	top1	1	0.03	3.6e-03	-5.1	-5.1	3.1e-07	0.64	0.08	0.06	FALSE
80	PL	Pet100	intron excision ratio	chr12:1680794:1680963	0.49	0.13	blup	1822	0.18	2.5e-13	-4.8	-5.3	1.1e-07	0.87	0.43	0.57	FALSE
81	PL	Insr	mRNA stability	ENSRNOG00000029986	0.65	0.46	lasso	32	0.49	2.3e-42	-5.5	5.2	2.1e-07	-0.98	0.12	0.88	FALSE
82	PL	Katnal1	mRNA stability	ENSRNOG00000047618	0.09	0.08	lasso	5	0.09	5.0e-07	-5.2	-5.5	4.3e-08	0.39	0.20	0.80	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.