Hub : Traits : sol weight in grams :

chr8:102,533,918-104,393,934

Best TWAS P=1.676286e-07 · Best GWAS P=4.147343e-08 conditioned to 1

Associated models

# Tissue Gene Modality RNA phenotype h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 Adipose Cep63 intron excision ratio chr8:103163124:103164803 0.06 0.01 lasso 1 0.01 2.2e-02 5.2 -5.2 2.2e-07 -0.77 0.27 0.41 FALSE
2 BLA Rab6b mRNA stability ENSRNOG00000009198 0.07 0.04 top1 1 0.04 3.6e-03 5.1 -5.1 3.1e-07 -0.56 0.08 0.09 FALSE
3 LHb Cep63 alternative polyA ENSRNOT00000031313 0.30 0.10 top1 1 0.10 2.4e-03 5.2 5.2 2.5e-07 0.94 0.09 0.06 FALSE
4 LHb Cep63 alternative polyA ENSRNOT00000031313 0.30 0.13 top1 1 0.13 6.3e-04 5.2 5.2 2.5e-07 0.94 0.09 0.07 FALSE
5 LHb Cep63 alternative polyA ENSRNOT00000084413 0.31 0.10 top1 1 0.10 1.9e-03 5.2 -5.2 2.5e-07 -0.95 0.09 0.06 FALSE
6 LHb Amotl2 gene expression ENSRNOG00000008487 0.39 0.19 lasso 4 0.21 9.3e-06 5.1 5.2 1.7e-07 0.96 0.28 0.72 TRUE
7 Liver Slco2a1 intron excision ratio chr8:103637317:103654517 0.09 0.04 top1 1 0.04 1.2e-05 5.2 -5.2 2.2e-07 -0.70 0.10 0.52 FALSE
8 Liver Slco2a1 intron excision ratio chr8:103641675:103654517 0.08 0.03 top1 1 0.03 7.2e-04 5.2 5.2 2.2e-07 0.81 0.05 0.07 FALSE
9 NAcc2 Amotl2 gene expression ENSRNOG00000008487 0.31 0.24 enet 25 0.29 8.4e-16 5.0 5.2 1.8e-07 0.71 0.34 0.66 FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.