chr7:7,178,376-11,501,489

Trait: Soleus weight

Best TWAS P = 1.16e-07 · Best GWAS P= 2.18e-07 conditioned to 2.59e-01

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Znf431l4 alternative polyA XM_006240824.5 0.09 3 0.07 2.0e-08 -5.24 1.62e-07 0.48 FALSE
Adipose Apc2 alternative TSS XM_039078652.2 0.06 1534 0.04 1.1e-05 5.21 1.87e-07 0.42 FALSE
Adipose Apc2 alternative TSS XM_063263171.1 0.02 1534 0.01 1.4e-02 -5.22 1.81e-07 0.33 FALSE
Adipose Apc2 alternative TSS XM_039078652.2 0.06 1534 0.04 8.5e-06 5.21 1.89e-07 0.42 FALSE
Adipose Plk5 alternative TSS XM_063263420.1 0.03 1417 0.02 2.5e-03 -5.22 1.83e-07 0.42 FALSE
Adipose Znf431l4 gene expression Znf431l4 0.1 14 0.08 8.7e-09 -5.28 1.27e-07 0.47 FALSE
Adipose Ndufs7 isoform ratio XM_006240972.5 0.03 1527 0.02 3.5e-03 -5.22 1.75e-07 0.4 FALSE
Adipose Arhgap45 intron excision ratio chr7_10339856_10340526 0.02 99 0.01 1.0e-02 5.26 1.43e-07 0.36 FALSE
Adipose Arhgap45 intron excision ratio chr7_10339856_10340711 0.02 67 0.01 1.1e-02 -5.28 1.31e-07 0.36 FALSE
Adipose Zfp709l3 intron excision ratio chr7_8270159_8281158 0.12 194 0.12 5.8e-13 -5.25 1.55e-07 0.44 FALSE
Adipose Apc2 mRNA stability Apc2 0.04 1534 0.02 1.1e-03 5.21 1.86e-07 0.42 FALSE
Adipose Csnk1g2 mRNA stability Csnk1g2 0.03 1494 0.02 5.1e-03 5.22 1.76e-07 0.35 FALSE
Adipose Gpx4 mRNA stability Gpx4 0.06 1399 0.05 1.2e-06 5.21 1.85e-07 0.46 FALSE
BLA Zfp347 alternative TSS XM_063262945.1 0.27 46 0.29 5.8e-16 5.25 1.54e-07 0.46 FALSE
BLA Prtn3 gene expression Prtn3 0.05 1656 0.04 2.3e-03 -5.22 1.80e-07 0.38 FALSE
BLA Pwwp3a gene expression Pwwp3a 0.27 1525 0.34 1.2e-18 5.25 1.56e-07 0.47 FALSE
BLA Cbarp isoform ratio NM_001388507.1 0.06 1417 0.06 2.5e-04 -5.21 1.92e-07 0.47 FALSE
BLA Cbarp intron excision ratio chr7_10217596_10219275 0.06 1417 0.06 4.8e-04 -5.23 1.72e-07 0.47 FALSE
BLA Izumo4 intron excision ratio chr7_9658924_9659145 0.04 1484 0.03 1.6e-02 -5.22 1.80e-07 0.32 FALSE
Brain Plk5 alternative polyA XM_006240922.5 0.06 1417 0.04 1.1e-04 5.23 1.68e-07 0.46 FALSE
Brain Csnk1g2 gene expression Csnk1g2 0.03 1494 0.02 3.7e-03 5.21 1.86e-07 0.39 FALSE
Brain LOC134479620 gene expression LOC134479620 0.03 1495 0.02 5.0e-03 -5.22 1.81e-07 0.36 FALSE
Brain Plk5 gene expression Plk5 0.35 1417 0.35 3.1e-34 5.21 1.89e-07 0.47 FALSE
Brain Pwwp3a gene expression Pwwp3a 0.32 203 0.32 1.9e-30 -5.24 1.61e-07 0.48 FALSE
Brain Reep6 gene expression Reep6 0.1 5 0.07 5.6e-07 5.26 1.48e-07 0.46 FALSE
Brain Rexo1 isoform ratio XM_063263421.1 0.05 1457 0.04 2.0e-04 5.24 1.57e-07 0.44 FALSE
Eye Midn alternative TSS XM_008765097.4 0.26 1417 0.15 2.3e-03 -5.23 1.66e-07 0.32 FALSE
IC Grin3b gene expression Grin3b 0.13 1400 0.06 2.2e-03 -5.21 1.93e-07 0.44 FALSE
IC Pwwp3a gene expression Pwwp3a 0.22 54 0.11 2.4e-05 -5.25 1.54e-07 0.44 FALSE
IC Scamp4 mRNA stability Scamp4 0.14 1509 0.07 4.6e-04 5.22 1.77e-07 0.4 FALSE
IL LOC134479811 gene expression LOC134479811 0.16 1423 0.05 2.0e-02 -5.23 1.66e-07 0.28 FALSE
IL Znf431l4 gene expression Znf431l4 0.25 13 0.1 2.0e-03 5.28 1.29e-07 0.34 FALSE
LHb Ndufs7 intron excision ratio chr7_10106899_10107410 0.18 1527 0.12 1.1e-03 -5.23 1.74e-07 0.4 FALSE
LHb Ndufs7 intron excision ratio chr7_10106899_10107529 0.13 1527 0.09 4.7e-03 5.23 1.74e-07 0.33 FALSE
Liver Zfp77 alternative polyA XM_063264477.1 0.37 356 0.3 3.8e-34 5.28 1.29e-07 0.48 FALSE
Liver Zfp77 alternative polyA XM_063264477.1 0.36 357 0.3 7.4e-34 5.26 1.43e-07 0.47 FALSE
Liver Rps15 alternative TSS XM_063263114.1 0.03 1540 0.02 4.4e-03 5.21 1.84e-07 0.39 FALSE
Liver Rps15 alternative TSS XM_063263114.1 0.03 1540 0.02 1.7e-03 5.21 1.88e-07 0.42 FALSE
Liver Rps15 alternative TSS XM_063263115.1 0.03 1540 0.02 1.1e-03 -5.22 1.80e-07 0.42 FALSE
Liver LOC108351405 gene expression LOC108351405 0.15 1444 0.15 2.4e-16 5.23 1.73e-07 0.47 FALSE
Liver Scamp4 gene expression Scamp4 0.07 301 0.06 2.0e-07 -5.3 1.16e-07 0.44 TRUE
Liver Pcsk4 mRNA stability Pcsk4 0.07 1445 0.06 3.8e-07 -5.23 1.72e-07 0.46 FALSE
NAcc Arhgap45 alternative TSS XM_039078979.2 0.04 1379 0.05 1.5e-07 -5.22 1.76e-07 0.49 FALSE
NAcc Arhgap45 alternative TSS XM_039078979.2 0.03 1379 0.04 4.1e-06 -5.23 1.66e-07 0.47 FALSE
NAcc C7h19orf25 gene expression C7h19orf25 0.09 28 0.07 1.8e-11 -5.3 1.17e-07 0.47 FALSE
NAcc Pwwp3a gene expression Pwwp3a 0.15 1525 0.17 3.0e-25 5.23 1.70e-07 0.41 FALSE
NAcc Reep6 gene expression Reep6 0.04 1443 0.04 7.6e-07 5.21 1.87e-07 0.45 FALSE
NAcc Arhgap45 isoform ratio XM_039078978.2 0.02 1379 0.02 4.0e-04 -5.23 1.68e-07 0.47 FALSE
NAcc Cbarp isoform ratio NM_001388507.1 0.04 1417 0.04 4.0e-06 -5.24 1.63e-07 0.49 FALSE
NAcc Midn isoform ratio XM_006240912.5 0.02 1417 0.03 9.4e-05 5.22 1.80e-07 0.47 FALSE
NAcc Plk5 isoform ratio XR_355240.5 0.11 1417 0.14 1.3e-20 5.22 1.82e-07 0.46 FALSE
NAcc Scamp4 mRNA stability Scamp4 0.02 1509 0.01 2.0e-03 5.23 1.73e-07 0.43 FALSE
NAcc Sf3a2 mRNA stability Sf3a2 0.06 1484 0.05 1.4e-08 5.22 1.76e-07 0.46 FALSE
OFC Gamt gene expression Gamt 0.15 1531 0.07 1.1e-02 -5.21 1.86e-07 0.37 FALSE
OFC Spmap2 gene expression Spmap2 0.46 474 0.36 1.8e-09 5.23 1.66e-07 0.33 FALSE
OFC Mier2 isoform ratio XR_010053000.1 0.31 437 0.3 7.4e-08 5.23 1.68e-07 0.34 FALSE
OFC Plk5 isoform ratio XR_355240.5 0.13 1417 0.11 1.5e-03 5.22 1.78e-07 0.37 FALSE
OFC Izumo4 mRNA stability Izumo4 0.16 1484 0.15 2.6e-04 -5.22 1.81e-07 0.39 FALSE
PL Atp5f1d alternative TSS XM_063262989.1 0.03 1417 0.03 2.2e-04 -5.23 1.70e-07 0.47 FALSE
PL Plk5 alternative TSS XM_039079005.2 0.08 1417 0.09 5.1e-10 -5.22 1.77e-07 0.46 FALSE
PL Zfp347 isoform ratio XM_039078333.2 0.06 17 0.04 7.3e-05 -5.29 1.23e-07 0.28 FALSE
PL Pcsk4 mRNA stability Pcsk4 0.02 1445 0.01 1.3e-02 -5.22 1.79e-07 0.38 FALSE
pVTA Apc2 alternative TSS XM_063263171.1 0.03 1534 0.02 6.9e-03 -5.22 1.80e-07 0.35 FALSE
pVTA Apc2 alternative TSS XM_063263171.1 0.02 1534 0.02 1.3e-02 -5.21 1.86e-07 0.34 FALSE
pVTA Apc2 gene expression Apc2 0.21 1534 0.25 1.0e-19 5.21 1.87e-07 0.47 FALSE
pVTA Fgf22 gene expression Fgf22 0.06 75 0.04 1.6e-04 -5.23 1.73e-07 0.38 FALSE
pVTA Pwwp3a gene expression Pwwp3a 0.15 1525 0.16 9.1e-13 5.24 1.63e-07 0.47 FALSE
pVTA LOC120093775 intron excision ratio chr7_9802860_9804622 0.03 1457 0.02 9.7e-03 5.23 1.69e-07 0.34 FALSE