chr6:56,652,686-59,547,170

Trait: Soleus weight

Best TWAS P = 1.56e-08 · Best GWAS P= 7.42e-09 conditioned to 2.67e-46

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Ahr gene expression Ahr 0.11 56 0.07 6.8e-08 5.58 2.46e-08 0.1 FALSE
Liver Hdac9 alternative TSS XM_063262492.1 0.03 1 0.02 3.0e-03 -5.64 1.66e-08 0.18 FALSE
Liver Ahr mRNA stability Ahr 0.02 2918 0.01 1.4e-02 5.3 1.18e-07 0.16 FALSE
PL Hdac9 alternative polyA NM_001200045.1 0.03 2250 0.02 1.2e-03 -5.55 2.90e-08 0.27 FALSE
PL Hdac9 alternative polyA XM_063262499.1 0.05 2250 0.04 3.1e-05 5.65 1.56e-08 0.22 TRUE
PL Hdac9 alternative polyA XM_063262503.1 0.05 2250 0.04 1.9e-05 -5.59 2.26e-08 0.23 FALSE
pVTA Hdac9 gene expression Hdac9 0.09 2250 0.06 6.2e-06 5.27 1.37e-07 0.82 FALSE
pVTA Crppa isoform ratio NM_001008386.1 0.04 13 0.02 4.9e-03 5.32 1.06e-07 0.49 FALSE