chr2:45,805,476-47,511,335

Trait: Soleus weight

Best TWAS P=3.47e-09 · Best GWAS P=1.92e-08 conditioned to 2.69e-13

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Itga2 mRNA stability Itga2 0.03 1 0.03 2.1e-04 -5.22 1.79e-07 0.15 FALSE
BLA Mocs2 isoform ratio NM_001162413.1 0.16 2101 0.11 3.0e-06 5.82 5.90e-09 0.57 FALSE
BLA Mocs2 isoform ratio NM_001395669.1 0.23 2101 0.22 3.1e-12 -5.2 1.96e-07 0.33 FALSE
BLA Mocs2 intron excision ratio chr2_46507444_46511052 0.21 37 0.18 3.7e-10 5.32 1.01e-07 0.25 TRUE
Brain Pelo gene expression Pelo 0.05 2824 0.04 2.3e-04 5.89 3.87e-09 0.46 TRUE
Brain Mocs2 intron excision ratio chr2_46507411_46511052 0.2 5 0.21 1.0e-19 -5.36 8.38e-08 0.28 TRUE
Brain Mocs2 intron excision ratio chr2_46507444_46511052 0.17 20 0.18 6.4e-17 -5.89 3.91e-09 0.33 FALSE
LHb Mocs2 intron excision ratio chr2_46507444_46511052 0.3 2101 0.13 5.9e-04 5.91 3.47e-09 0.42 TRUE
Liver Mocs2 intron excision ratio chr2_46505866_46507267 0.15 23 0.16 5.0e-17 5.89 3.84e-09 0.59 FALSE
Liver Mocs2 intron excision ratio chr2_46507411_46511052 0.17 9 0.15 6.7e-16 -5.18 2.19e-07 0.46 FALSE
Liver Mocs2 mRNA stability Mocs2 0.04 1 0.05 3.3e-06 -5.39 7.13e-08 0.74 FALSE
NAcc Itga2 gene expression Itga2 0.36 39 0.44 2.5e-55 -5.19 2.06e-07 0.42 FALSE
NAcc Mocs2 isoform ratio NM_001395669.1 0.25 25 0.22 1.6e-25 5.64 1.72e-08 0.26 FALSE
NAcc Mocs2 intron excision ratio chr2_46507411_46511052 0.35 25 0.28 6.3e-32 -5.18 2.18e-07 0.2 FALSE
NAcc Mocs2 intron excision ratio chr2_46507444_46511052 0.29 12 0.22 6.2e-25 5.8 6.58e-09 0.42 TRUE
PL Itga1 gene expression Itga1 0.03 2497 0.02 1.4e-03 5.84 5.31e-09 0.35 FALSE
PL Mocs2 intron excision ratio chr2_46507444_46511052 0.2 2101 0.22 4.9e-24 5.19 2.16e-07 0.42 FALSE
RMTg Itga1 gene expression Itga1 0.14 1 0.05 1.9e-02 -5.32 1.01e-07 0.06 TRUE