Hub : Traits : Soleus weight : →

chr2:45,805,476-47,498,986

Trait: Soleus weight

Best TWAS P=1.23527e-09 · Best GWAS P=1.918992e-08 conditioned to 0.008654859

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	Liver	Mocs2	mRNA stability	ENSRNOG00000056325	0.04	0.05	top1	1	0.05	4.3e-06	5.4	5.4	7.1e-08	0.89	0.14	0.76	FALSE
7	Liver	Mocs2	intron excision ratio	chr2:46505866:46507267	0.15	0.13	enet	20	0.16	3.4e-17	4.8	-5.9	4.5e-09	-0.88	0.41	0.59	FALSE
12	PL	Mocs2	intron excision ratio	chr2:46507444:46511052	0.22	0.18	enet	115	0.22	1.1e-16	4.7	5.5	4.0e-08	0.83	0.48	0.52	FALSE
11	NAcc	Mocs2	intron excision ratio	chr2:46507444:46511052	0.30	0.23	lasso	18	0.24	9.9e-18	4.8	5.8	6.3e-09	-0.66	0.56	0.44	TRUE
3	Brain	Pelo	gene expression	ENSRNOG00000061128	0.05	0.02	blup	2797	0.04	2.6e-04	5.1	5.9	2.8e-09	0.78	0.52	0.44	FALSE
8	Liver	Mocs2	intron excision ratio	chr2:46507411:46511052	0.16	0.14	lasso	8	0.16	3.6e-17	4.9	-5.1	2.7e-07	-0.89	0.57	0.43	FALSE
1	Adipose	Itga2	mRNA stability	ENSRNOG00000058111	0.03	0.01	blup	2593	0.01	2.0e-02	5.2	5.8	6.0e-09	0.69	0.42	0.43	FALSE
6	LHb	Mocs2	intron excision ratio	chr2:46507444:46511052	0.29	0.06	enet	87	0.07	1.2e-02	5.0	6.1	1.2e-09	0.87	0.36	0.40	TRUE
9	Liver	Mocs2	intron excision ratio	chr2:46507444:46511052	0.19	0.17	lasso	8	0.18	2.0e-19	4.6	5.1	3.3e-07	0.88	0.62	0.38	FALSE
4	Brain	Mocs2	intron excision ratio	chr2:46507444:46511052	0.16	0.14	enet	36	0.16	6.3e-15	4.9	5.8	7.7e-09	0.83	0.73	0.27	TRUE
2	BLA	Mocs2	intron excision ratio	chr2:46507444:46511052	0.23	0.14	blup	2080	0.21	2.3e-11	4.6	5.2	1.8e-07	0.86	0.78	0.22	FALSE
5	LHb	Mocs2	intron excision ratio	chr2:46507411:46511052	0.24	0.11	top1	1	0.11	1.6e-03	5.2	-5.2	2.1e-07	-0.92	0.11	0.06	TRUE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.