Best TWAS P = 1.01e-07 · Best GWAS P= 4.29e-08 conditioned to 1.24e-01
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Slco2a1 | mRNA stability | Slco2a1 | 0.07 | 9 | 0.01 | 1.1e-02 | -5.23 | 1.74e-07 | 0.44 | FALSE |
| LHb | Amotl2 | gene expression | Amotl2 | 0.37 | 1786 | 0.25 | 1.3e-06 | 5.32 | 1.01e-07 | 0.72 | TRUE |