Hub : Traits : Soleus weight : ←

chr20:5,086,090-6,657,065

Trait: Soleus weight

Best TWAS P=8.332858e-08 · Best GWAS P=6.79307e-08 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Spdef	gene expression	ENSRNOG00000000491	0.11	0.05	top1	1	0.05	7.4e-06	5.3	-5.3	1.3e-07	-0.61	0.07	0.77	TRUE
2	Adipose	Ilrun	gene expression	ENSRNOG00000038883	0.72	0.42	enet	101	0.52	9.1e-68	5.3	-5.2	2.1e-07	-0.92	0.10	0.90	TRUE
3	Liver	Snrpc	gene expression	ENSRNOG00000000493	0.90	0.25	enet	147	0.48	1.8e-59	5.3	5.4	8.8e-08	0.92	0.10	0.90	FALSE
4	Liver	Taf11	gene expression	ENSRNOG00000024601	0.09	0.02	enet	58	0.03	5.0e-04	2.7	5.4	8.3e-08	0.38	0.61	0.29	TRUE
5	Liver	Ilrun	gene expression	ENSRNOG00000038883	0.87	0.40	enet	68	0.41	7.0e-49	5.3	-5.1	3.2e-07	-0.99	0.10	0.90	TRUE
6	NAcc	NA	gene expression	ENSRNOG00000058912	0.21	0.11	top1	1	0.11	2.2e-08	5.3	-5.3	1.3e-07	-0.60	0.07	0.93	TRUE
7	PL	NA	gene expression	ENSRNOG00000058912	0.37	0.16	blup	2282	0.17	1.2e-12	5.3	-5.3	1.2e-07	-0.96	0.08	0.92	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.