Hub : Traits : Soleus weight : ← : →

chr4:19,000,780-21,703,243

Trait: Soleus weight

Best TWAS P = 4.23e-12 · Best GWAS P= 2.33e-12 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	LOC134486713	gene expression	LOC134486713	0.05	2539	0.06	3.4e-07	6.85	7.41e-12	0.39	FALSE
Adipose	LOC134486713	isoform ratio	XR_010066066.1	0.02	1	0.01	2.4e-02	-6.65	2.90e-11	0.03	FALSE
Adipose	LOC134486713	isoform ratio	XR_010066067.1	0.02	1	0.01	2.7e-02	6.65	2.90e-11	0.03	FALSE
BLA	Hgf	alternative polyA	NM_017017.2	0.06	2460	0.03	6.2e-03	5.48	4.28e-08	0.08	FALSE
BLA	Hgf	alternative polyA	XM_006235979.5	0.05	2460	0.02	2.2e-02	-5.68	1.35e-08	0.1	FALSE
BLA	Hgf	gene expression	Hgf	0.05	2456	0.04	3.8e-03	-6.57	4.94e-11	0.3	FALSE
Brain	Hgf	alternative polyA	NM_017017.2	0.02	1	0.02	2.7e-03	-6.75	1.51e-11	0.03	FALSE
Brain	Hgf	alternative polyA	XM_006235979.5	0.02	1	0.02	3.0e-03	6.48	9.47e-11	0.03	FALSE
Brain	Pclo	alternative polyA	XM_039108295.2	0.24	1	0.11	2.4e-10	-6.05	1.44e-09	0.16	FALSE
Brain	Pclo	alternative polyA	XM_063286640.1	0.24	1	0.1	9.1e-10	6.05	1.44e-09	0.16	FALSE
Brain	Pclo	alternative polyA	XM_039108295.2	0.24	1	0.11	1.8e-10	-6.05	1.44e-09	0.16	FALSE
Brain	Pclo	alternative polyA	XM_063286640.1	0.26	1	0.11	5.3e-10	6.05	1.44e-09	0.16	FALSE
Brain	Cacna2d1	gene expression	Cacna2d1	0.95	1	0.34	2.1e-32	6.86	6.65e-12	0.37	FALSE
Brain	Cacna2d1	isoform ratio	NM_012919.3	0.11	9	0.06	3.1e-06	6.81	1.01e-11	0.39	FALSE
Brain	Pclo	isoform ratio	XM_063286640.1	0.22	2913	0.11	7.9e-11	-5.35	9.01e-08	0.22	FALSE
IC	Cacna2d1	gene expression	Cacna2d1	0.06	2787	0.03	1.4e-02	-6.24	4.27e-10	0.27	FALSE
IL	Cacna2d1	gene expression	Cacna2d1	0.46	2787	0.22	5.6e-06	-6.66	2.66e-11	0.39	FALSE
LHb	Pclo	alternative polyA	XM_063286640.1	0.4	27	0.05	2.9e-02	-5.27	1.34e-07	0.3	FALSE
LHb	Pclo	alternative polyA	XM_063286640.1	0.42	19	0.05	2.5e-02	-5.29	1.24e-07	0.32	FALSE
Liver	Cacna2d1	gene expression	Cacna2d1	0.16	113	0.05	1.4e-06	-5.28	1.30e-07	0	FALSE
Liver	LOC134486713	gene expression	LOC134486713	0.33	37	0.29	8.8e-33	6.93	4.23e-12	0.36	TRUE
Liver	LOC134486713	isoform ratio	XR_010066066.1	0.2	34	0.19	1.8e-20	6.79	1.12e-11	0.44	FALSE
Liver	LOC134486713	isoform ratio	XR_010066067.1	0.23	2539	0.2	9.5e-22	-6.58	4.60e-11	0.44	FALSE
NAcc	Pclo	alternative polyA	XM_063286640.1	0.07	1	0.02	7.1e-04	5.25	1.52e-07	0.02	FALSE
NAcc	Pclo	alternative polyA	XM_063286640.1	0.07	1	0.02	1.0e-03	5.25	1.52e-07	0.02	FALSE
NAcc	Cacna2d1	gene expression	Cacna2d1	0.63	2787	0.28	6.6e-42	-6.41	1.48e-10	0.43	FALSE
NAcc	LOC134486713	gene expression	LOC134486713	0.04	2539	0.03	5.8e-06	6.44	1.20e-10	0.35	FALSE
NAcc	Cacna2d1	intron excision ratio	chr4_19948697_19950353	0.01	1	0.02	4.2e-04	6.71	1.95e-11	0.03	FALSE
PL	Pclo	isoform ratio	NM_020098.2	0.11	11	0.03	1.2e-04	-5.53	3.13e-08	0.49	FALSE
PL	Hgf	mRNA stability	Hgf	0.02	2460	0.02	2.8e-03	-5.6	2.17e-08	0.09	FALSE