chr4:18,045,586-20,728,817

Trait: Soleus weight

Best TWAS P=8.13e-12 · Best GWAS P=7.40e-12 conditioned to 1.00e+00

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Brain Pclo alternative polyA ENSRNOT00000007608 0.08 6 0.04 2.3e-04 -5.91 3.42e-09 0.62 FALSE
Brain Pclo alternative polyA ENSRNOT00000008637 0.08 6 0.04 1.9e-04 5.88 4.19e-09 0.61 FALSE
Brain Cacna2d1 gene expression ENSRNOG00000033531 0.05 1 0.06 5.7e-06 -6.84 8.13e-12 0.47 TRUE
Brain Pclo isoform ratio ENSRNOT00000007608 0.05 29 0.03 1.0e-03 -5.9 3.59e-09 0.48 FALSE
Brain Pclo isoform ratio ENSRNOT00000008637 0.05 30 0.03 5.5e-04 5.82 5.78e-09 0.5 FALSE
Brain Pclo mRNA stability ENSRNOG00000005726 0.28 64 0.24 4.1e-22 5.62 1.87e-08 0.19 FALSE
IL Hgf gene expression ENSRNOG00000007027 0.45 18 0.34 6.6e-09 -5.16 2.41e-07 0 FALSE
LHb Pclo intron excision ratio chr4:19838555:19842972 0.18 6 0.05 2.9e-02 -5.46 4.87e-08 0.22 FALSE
NAcc Cacna2d1 gene expression ENSRNOG00000033531 0.81 2673 0.04 8.0e-04 -5.29 1.24e-07 0.41 FALSE