Best TWAS P=1.626301e-10 · Best GWAS P=0.0159346 conditioned to 8.613829e-11
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Liver | Stk40 | mRNA stability | ENSRNOG00000025679 | 0.26 | 0.04 | blup | 1102 | 0.13 | 2e-14 | -0.42 | -6.4 | 1.6e-10 | -0.87 | 0.04 | 0.02 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.