Best TWAS P=1.025355e-07 · Best GWAS P=4.776118e-08 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NAcc | Cpne3 | gene expression | ENSRNOG00000006298 | 0.33 | 0.08 | blup | 3113 | 0.11 | 1.6e-03 | -5.4 | 5.3 | 1.3e-07 | -0.95 | 0.50 | 0.39 | FALSE |
| 2 | NAcc2 | Atp6v0d2 | gene expression | ENSRNOG00000006926 | 0.06 | 0.02 | top1 | 1 | 0.02 | 3.3e-02 | -5.2 | 5.2 | 2.4e-07 | -0.67 | 0.10 | 0.05 | FALSE |
| 3 | NAcc2 | Cpne3 | mRNA stability | ENSRNOG00000006298 | 0.14 | 0.07 | blup | 2808 | 0.08 | 5.8e-05 | -4.5 | -5.1 | 3.2e-07 | 0.91 | 0.63 | 0.37 | FALSE |
| 4 | PL2 | Cpne3 | gene expression | ENSRNOG00000006298 | 0.06 | 0.01 | blup | 2808 | 0.03 | 1.4e-02 | -5.3 | 5.3 | 1.0e-07 | -0.93 | 0.45 | 0.37 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.