Best TWAS P = 2.15e-08 · Best GWAS P= 1.94e-08 conditioned to 4.04e-02
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Brain | Runx1t1l | gene expression | Runx1t1l | 0.04 | 1 | 0.03 | 7.9e-04 | 5.49 | 3.99e-08 | 0.08 | FALSE |
| IC | Runx1t1l | intron excision ratio | chr5_31966850_31971834 | 0.1 | 7 | 0.05 | 4.7e-03 | 5.25 | 1.52e-07 | 0.38 | FALSE |
| LHb | Runx1t1l | intron excision ratio | chr5_31966893_31971834 | 0.18 | 1 | 0.08 | 4.9e-03 | 5.47 | 4.57e-08 | 0.06 | FALSE |
| NAcc | Runx1t1l | gene expression | Runx1t1l | 0.09 | 1 | 0.09 | 8.7e-14 | 5.36 | 8.51e-08 | 0.62 | FALSE |
| NAcc | Runx1t1 | mRNA stability | Runx1t1 | 0.05 | 136 | 0.04 | 2.3e-07 | 5.6 | 2.15e-08 | 0.37 | TRUE |