Best TWAS P=1.71e-08 · Best GWAS P=1.46e-09 conditioned to 6.05e-03
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Pld1 | mRNA stability | Pld1 | 0.04 | 2200 | 0.02 | 4.4e-03 | -5.42 | 5.88e-08 | 0.48 | FALSE |
| Adipose | Tnik | mRNA stability | Tnik | 0.12 | 2389 | 0.07 | 3.2e-08 | 5.44 | 5.38e-08 | 0.59 | FALSE |
| Brain | Pld1 | gene expression | Pld1 | 0.05 | 53 | 0.02 | 2.5e-03 | 5.52 | 3.43e-08 | 0.5 | FALSE |
| LHb | Fndc3b | mRNA stability | Fndc3b | 0.23 | 2049 | 0.13 | 7.0e-04 | 5.25 | 1.49e-07 | 0.54 | FALSE |
| Liver | Slc2a2 | gene expression | Slc2a2 | 0.13 | 2313 | 0.06 | 8.3e-07 | -5.37 | 7.99e-08 | 0.35 | FALSE |
| Liver | Slc2a2 | isoform ratio | XM_039101783.1 | 0.15 | 2313 | 0.1 | 1.3e-11 | 5.18 | 2.24e-07 | 0.38 | FALSE |
| NAcc | Pld1 | gene expression | Pld1 | 0.03 | 2200 | 0.02 | 7.5e-04 | -5.23 | 1.67e-07 | 0.56 | FALSE |
| NAcc | Pld1 | intron excision ratio | chr2_110979168_110986670 | 0.05 | 13 | 0.03 | 5.6e-04 | -5.64 | 1.71e-08 | 0.48 | TRUE |