Best TWAS P=3.34e-09 · Best GWAS P=6.75e-10 conditioned to 7.84e-50
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | ENSRNOG00000067235 | mRNA stability | ENSRNOG00000067235 | 0.03 | 1 | 0.01 | 7.9e-03 | 5.26 | 1.42e-07 | 0.03 | FALSE |
| Brain | Pld1 | gene expression | ENSRNOG00000028156 | 0.07 | 19 | 0.04 | 5.1e-05 | -5.48 | 4.21e-08 | 0.66 | FALSE |
| LHb | Mecom | isoform ratio | ENSRNOT00000099354 | 0.31 | 1607 | 0.13 | 6.2e-04 | -5.51 | 3.58e-08 | 0.54 | FALSE |
| Liver | Slc2a2 | gene expression | ENSRNOG00000011875 | 0.1 | 1 | 0.04 | 1.5e-05 | -5.91 | 3.34e-09 | 0.9 | TRUE |
| NAcc | Pld1 | gene expression | ENSRNOG00000028156 | 0.05 | 74 | 0.04 | 1.2e-03 | -5.36 | 8.14e-08 | 0.5 | FALSE |
| NAcc | Pld1 | intron excision ratio | chr2:110980055:110986670 | 0.08 | 1 | 0.04 | 1.2e-03 | -5.75 | 8.83e-09 | 0.04 | FALSE |