chr2:111,268,894-114,237,500

Trait: Soleus weight

Best TWAS P = 6.00e-09 · Best GWAS P= 4.44e-10 conditioned to 1.00e+00

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Fndc3b gene expression Fndc3b 0.15 2066 0.1 6.1e-11 5.38 7.61e-08 0.66 TRUE
Adipose LOC120100791 gene expression LOC120100791 0.05 65 0.03 2.8e-04 5.34 9.28e-08 0.46 FALSE
Adipose Pld1 mRNA stability Pld1 0.05 2216 0.02 8.8e-04 -5.48 4.20e-08 0.53 FALSE
Adipose Tnik mRNA stability Tnik 0.09 2418 0.05 2.2e-06 5.47 4.53e-08 0.53 FALSE
Brain Pld1 isoform ratio NM_001399082.1 0.03 6 0.01 7.7e-02 5.77 7.83e-09 0.47 FALSE
Liver Slc2a2 gene expression Slc2a2 0.12 2329 0.06 2.8e-07 -5.43 5.55e-08 0.47 FALSE
NAcc Pld1 gene expression Pld1 0.05 2216 0.06 6.7e-09 -5.82 6.00e-09 0.62 TRUE
RMTg Ect2 alternative TSS NM_001108547.3 0.54 1 0.11 6.5e-04 5.69 1.29e-08 0.09 TRUE